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EC Tree
Synonyms
Q10H2 oxidase,
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2,3-dimethylnaphthohydroquinone + O2
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menadione + O2
?
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?
menaquinol-4 + O2
menaquinone-4 + H2O
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menaquinols are oxidized at 6-12fold higher rates than ubiquinols
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?
thermoplasmaquinol + O2
thermoplasmaquinone + H2O
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likely candidate to the physiological electron donor
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?
ubiquinol-1 + O2
ubiquinone-1 + H2O
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?
ubiquinol-10 + O2
ubiquinone-10 + H2O
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menaquinols are oxidized at 6-12fold higher rates than ubiquinols. However, because of the greater tendency for autoxidation of menaquinols, ubiquinol is a more convenient substrate for the enzyme assay
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?
ubiquinol-6 + O2
ubiquinone-6 + H2O
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?
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thermoplasmaquinol + O2
thermoplasmaquinone + H2O
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likely candidate to the physiological electron donor
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?
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cytochrome
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cytochrome-o-type quinol oxidase
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2-hydroxy-3-undecyl-1,4-naphthoquinone
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0.01 mM, 20% inhibition
2n-heptyl-4-hydroxyquinoline N-oxide
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most potent inhibitor
Lipid
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addition of total lipids from Thermoplasma acidophilum decreases activity
additional information
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antimycin A, myxothiazol, methyl 3-methoxy-2-(2-styrylphenyl) propenate and stigmatellin (at concentration up to 0.030 mM) and Zn2+ at a concentration up to 1 mM, do not inhibit
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0.018
ubiquinol-10
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pH 5.4, 50°C
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0.00015
2n-heptyl-4-hydroxyquinoline N-oxide
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pH 5.4, 50°C
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brenda
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brenda
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oligomer
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12-16 * 14000, SDS-PAGE
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addition of total lipids from Thermoplasma acidophilum increases stability
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asolectin from soya beans decreases stability
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stability is lowered by the presence of detergent
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Gartner, P.
Characterization of a quinole-oxidase activity in crude extracts of Thermoplasma acidophilum and isolation of an 18-kDa cytochrome
Eur. J. Biochem.
200
215-222
1991
Thermoplasma acidophilum
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1.10.3.12 menaquinol oxidase (H+-transporting)
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