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Disease on EC 1.10.3.11 - ubiquinol oxidase (non-electrogenic)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Bacterial Infections
Transient transcriptional regulation of the CYS-C1 gene and cyanide accumulation upon pathogen infection in the plant immune response.
Carcinoma
The respiratory behavior of Lewis carcinoma cells--existence of a cyanide-resistant respiration.
Cytochrome-c Oxidase Deficiency
Diiron centre mutations in Ciona intestinalis alternative oxidase abolish enzymatic activity and prevent rescue of cytochrome oxidase deficiency in flies.
Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency.
Expression of the alternative oxidase complements cytochrome c oxidase deficiency in human cells.
The alternative oxidase AOX does not rescue the phenotype of tko25t mutant flies.
The alternative oxidase, a tool for compensating cytochrome c oxidase deficiency in human cells
The alternative oxidase, a tool for compensating cytochrome c oxidase deficiency in human cells.
The male sterile G cytoplasm of wild beet displays modified mitochondrial respiratory complexes.
Dehydration
Effects of water stress on development, operation and gene expression of cyanide-resistant respiratory pathway in wheat.
Effects of water stress on respiration in soybean leaves.
Implications of terminal oxidase function in regulation of salicylic acid on soybean seedling photosynthetic performance under water stress.
The response difference of mitochondria in recalcitrant Antiaris toxicaria axes and orthodox Zea mays embryos to dehydration injury.
Water stress enhances expression of genes encoding plastid terminal oxidase and key components of chlororespiration and alternative respiration in soybean seedlings.
Heart Diseases
Sea squirt alternative oxidase bypasses fatal mitochondrial heart disease.
Infections
Alternative oxidase mediates pathogen resistance in Paracoccidioides brasiliensis infection.
Alternative oxidase reduces the sensitivity of Mycosphaerella graminicola to QOI fungicides.
Disruption of the alternative oxidase gene in Magnaporthe grisea and its impact on host infection.
Enhanced expression and activation of the alternative oxidase during infection of Arabidopsis with Pseudomonas syringae pv tomato.
N-n-alkyl-3,4-dihydroxybenzamides as inhibitors of the trypanosome alternative oxidase: activity in vitro and in vivo.
The Effects of Salicylic Acid and Tobacco Mosaic Virus Infection on the Alternative Oxidase of Tobacco.
The influence of RNA-dependent RNA polymerase 1 on potato virus Y infection and on other antiviral response genes.
Toward More Drug Like Inhibitors of Trypanosome Alternative Oxidase.
Infertility, Female
Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease.
Infertility, Male
Partial male sterility in transgenic tobacco carrying an antisense gene for alternative oxidase under the control of a tapetum-specific promoter.
Malaria
Alternative oxidase inhibitors potentiate the activity of atovaquone against Plasmodium falciparum.
Mitochondrial Diseases
Alternative NAD(P)H dehydrogenase and alternative oxidase: Proposed physiological roles in animals.
Engineering the alternative oxidase gene to better understand and counteract mitochondrial defects: state of the art and perspectives.
nadh:ubiquinone reductase (h+-translocating) deficiency
Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila.
Paracoccidioidomycosis
Alternative oxidase mediates pathogen resistance in Paracoccidioides brasiliensis infection.
Phytoplasma Disease
Heterologous expression of an alternative oxidase from Moniliophthora perniciosa in Saccharomyces cerevisiae: antioxidant function and in vivo platform for the study of new drugs against witches' broom disease.
Synthesis and testing of novel alternative oxidase (AOX) inhibitors with antifungal activity against Moniliophthora perniciosa (Stahel), the causal agent of witches' broom disease of cocoa, and other phytopathogens.
Starvation
An Adaptation to Low Copper in Candida albicans Involving SOD Enzymes and the Alternative Oxidase.
Nitric oxide induces the alternative oxidase pathway in Arabidopsis seedlings deprived of inorganic phosphate.
Regulation of alternative oxidase 1 in Chlamydomonas reinhardtii during sulfur starvation.
Whole-plant respiration and its temperature sensitivity during progressive carbon starvation
Whole-plant respiration and its temperature sensitivity during progressive carbon starvation.
Trypanosomiasis
Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidase from Trypanosoma brucei brucei.
Probing the ubiquinol-binding site of recombinant Sauromatum guttatum alternative oxidase expressed in E. coli membranes through site-directed mutagenesis.
Purification and kinetic characterization of recombinant alternative oxidase from Trypanosoma brucei brucei.
The alternative oxidases: simple oxidoreductase proteins with complex functions.
Trypanosomiasis, African
African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase.
Functional expression of the ascofuranone-sensitive Trypanosoma brucei brucei alternative oxidase in the cytoplasmic membrane of Escherichia coli.
Overproduction of highly active trypanosome alternative oxidase in Escherichia coli heme-deficient mutant.
Strain-specific difference in amino acid sequences of trypanosome alternative oxidase.
Trypanosome alternative oxidase as a target of chemotherapy.
Trypanosome alternative oxidase: from molecule to function.
[Mitochondria as targets of chemotherapy].
Tuberculosis
The carboxy-terminal insert in the Q-loop is needed for functionality of Escherichia coli cytochrome bd-I.
ubiquinol oxidase (non-electrogenic) deficiency
Effects of AOX1a deficiency on plant growth, gene expression of respiratory components, and metabolic profile under low-nitrogen stress in Arabidopsis thaliana plants.
Importance of the alternative oxidase (AOX) pathway in regulating cellular redox and ROS homeostasis to optimize photosynthesis during restriction of the cytochrome oxidase pathway in Arabidopsis thaliana.
Virus Diseases
Ethylene is involved in leafy mustard systemic resistance to Turnip mosaic virus infection through the mitochondrial alternative oxidase pathway
Inhibition of Satellite RNA Associated Cucumber Mosaic Virus Infection by Essential Oil of Micromeria croatica (Pers.) Schott.
The Effects of Salicylic Acid and Tobacco Mosaic Virus Infection on the Alternative Oxidase of Tobacco.