Any feedback?
No. of entries
Information on EC 1.1.99.30 - 2-oxo-acid reductase
for references in articles please use BRENDA:EC1.1.99.30
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree 1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.99 With unknown physiological acceptors
1.1.99.30 2-oxo-acid reductase
IUBMB Comments
Contains [4Fe-4S] and a mononucleotide molybdenum (pyranopterin) cofactor. Has broad substrate specificity, with 2-oxo-monocarboxylates and 2-oxo-dicarboxylates acting as substrates. Branching in a substrate at the C-3 position results in loss of activity. The enzyme from Proteus sp. is inactivated by oxygen.
The enzyme appears in viruses and cellular organisms
Reaction Schemes
showSynonyms
2-oxo-acid reductase, more
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
(2R)-hydroxycarboxylate-viologen-oxidoreductase
-
-
-
-
2-oxoacid reductase
HVOR
2-oxoacid reductase
-
-
-
-
HVOR
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor
-
-
-
-
a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor
mechanism
-
a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor
Contains [4Fe-4S] and a mononucleotide molybdenum (pyranopterin) cofactor. Has broad substrate specificity, with 2-oxo-monocarboxylates and 2-oxo-dicarboxylates acting as substrates. Branching in a substrate at the C-3 position results in loss of activity. The enzyme from Proteus sp. is inactivated by oxygen
-
-
-
a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor
aldonates and aldarates with an (R)-configured alpha-carbon atom are converted to the corresponding 2-oxocarboxylates
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYSTEMATIC NAME
IUBMB Comments
(2R)-hydroxy-carboxylate:acceptor oxidoreductase
Contains [4Fe-4S] and a mononucleotide molybdenum (pyranopterin) cofactor. Has broad substrate specificity, with 2-oxo-monocarboxylates and 2-oxo-dicarboxylates acting as substrates. Branching in a substrate at the C-3 position results in loss of activity. The enzyme from Proteus sp. is inactivated by oxygen.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CAS REGISTRY NUMBER
COMMENTARY
70852-00-5
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(2R)-hydroxy-4-methylpentanoate + 2-oxo-butyrate
2-oxo-4-methylpentanoate + (2R)-hydroxybutyrate
-
Substrates: -
Products: -
Products: -
r
(2S,3R,4S)-2-hydroxy-3-halogenbutyrolactones + reduced benzyl viologen
?
-
Substrates: highly stereospecific reaction
Products: -
Products: -
r
(2S,3R,4S)-2-hydroxy-3-halogenbutyrolactones + reduced methyl viologen
?
-
Substrates: highly stereospecific reaction
Products: -
Products: -
r
(R)-lactate + oxidized anthraquinone-2,6-disulfonate
pyruvate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
?
(R,S)-2-oxo-3-methylpentanoate + reduced benzyl viologen
2-hydroxy-3-methylpentanoate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
(R,S)-2-oxo-3-methylpentanoate + reduced methyl viologen
2-hydroxy-3-methylpentanoate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
(S)-2-oxo-3-methylpentanoate + reduced benzyl viologen
2-hydroxy-3-methylpentanoate + oxidized benzyl viologen
(S)-2-oxo-3-methylpentanoate + reduced methyl viologen
2-hydroxy-3-methylpentanoate + oxidized methyl viologen
2-hydroxyglutarate + oxidized acceptor
2-oxoglutarate + reduced acceptor
-
Substrates: -
Products: -
Products: -
r
2-oxo-3,3-dimethyl-4-hydroxybutanoate + reduced benzyl viologen
3,3-dimethyl-2,4-dihydroxybutanoate + oxidized benzyl viologen
2-oxo-3,3-dimethyl-4-hydroxybutanoate + reduced methyl viologen
3,3-dimethyl-2,4-dihydroxybutanoate + oxidized methyl viologen
2-oxo-3-(3,4-dihydroxyphenyl)-propionate + H2
rosmarinic acid
-
Substrates: -
Products: -
Products: -
r
2-oxo-4-(hydroxy-methyl-phosphinyl)-butanoate + reduced benzyl viologen
2-hydroxy-4-(hydroxymethylphosphinyl)-butanoate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxo-4-(hydroxy-methyl-phosphinyl)-butanoate + reduced methyl viologen
2-hydroxy-4-(hydroxymethylphosphinyl)-butanoate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxo-4-methylpentanoate + reduced benzyl viologen
2-hydroxy-4-methylpentanoate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxo-4-methylpentanoate + reduced methyl viologen
2-hydroxy-4-methylpentanoate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxo-carboxylate + reduced benzyl viologen
(2R)-hydroxy-carboxylate + oxidized benzyl viologen
-
Substrates: stereospecific, very wide substrate specificity, reduces 2-oxo-carboxylates with diverse types of residues at position 3, such as unbranched and branched alkyl, hydroxy, one or two conjugated carbon carbon double bonds, additional CO, and -OOC(CH2)n, overview
Products: -
Products: -
r
2-oxo-carboxylate + reduced methyl viologen
(2R)-hydroxy-carboxylate + oxidized methyl viologen
-
Substrates: stereospecific, very wide substrate specificity, reduces 2-oxo-carboxylates with diverse types of residues at position 3, such as unbranched and branched alkyl, hydroxy, one or two conjugated carbon carbon double bonds, additional CO, and -OOC(CH2)n, overview
Products: -
Products: -
r
2-oxoadipate + reduced benzyl viologen
2-hydroxyadipate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxoadipate + reduced methyl viologen
2-hydroxyadipate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxononanoate + reduced benzyl viologen
2-hydroxynonanoate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxononanoate + reduced methyl viologen
2-hydroxynonanoate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
3-fluoropyruvate + reduced benzyl viologen
3-fluoro-2-hydroxypropionate + oxidized benzyl viologen
3-fluoropyruvate + reduced methyl viologen
3-fluoro-2-hydroxypropionate + oxidized methyl viologen
5-benzyloxyindolylpyruvate + reduced benzyl viologen
3-(5-benzyloxyindolyl)-2-hydroxypropionate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
5-benzyloxyindolylpyruvate + reduced methyl viologen
3-(5-benzyloxyindolyl)-2-hydroxypropionate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
6-phospho-D-gluconate + oxidized anthraquinone-2,6-disulfonate
6-phospho-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
6-phospho-D-gluconate + oxidized benzyl viologen
6-phospho-D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
6-phospho-D-gluconate + oxidized carboxamido-methyl viologen
6-phospho-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
chloropyruvic acid + reduced 1,1'-carbamoyl methyl viologen
D-(S)-chlorolactate + oxidized 1,1'-carbamoyl methyl viologen
-
Substrates: stereospecific reaction
Products: -
Products: -
?
D-galactonate + oxidized anthraquinone-2,6-disulfonate
D-lyxo-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
D-galactonate + oxidized benzyl viologen
D-lyxo-hex-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
D-galactonate + oxidized carboxamido-methyl viologen
D-lyxo-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
D-glucarate + oxidized anthraquinone-2,6-disulfonate
2-oxo-D-glucarate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
D-glucarate + oxidized benzyl viologen
2-oxo-D-glucarate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
D-glucarate + oxidized carboxamido-methyl viologen
2-oxo-D-glucarate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
D-gluconate + oxidized 1,1'-carbamoyl methyl viologen
? + reduced 1,1'-carbamoyl methyl viologen
-
Substrates: anaerobic conditions
Products: -
Products: -
r
D-gluconate + oxidized anthraquinone-2,6-disulfonate
D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
D-gluconate + oxidized benzyl viologen
D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
D-gluconate + oxidized carboxamido-methyl viologen
D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
D-glucose 6-phosphate + oxidized 1,1'-carbamoyl methyl viologen
? + reduced 1,1'-carbamoyl methyl viologen
-
Substrates: anaerobic conditions
Products: -
Products: -
r
D-gulonate + oxidized anthraquinone-2,6-disulfonate
D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
D-gulonate + oxidized benzyl viologen
D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
D-gulonate + oxidized carboxamido-methyl viologen
D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
D-lactate + oxidized 1,1'-carbamoyl methyl viologen
pyruvate + reduced 1,1'-carbamoyl methyl viologen
-
Substrates: anaerobic conditions
Products: -
Products: -
r
D-lactate + oxidized anthraquinone-2,6-disulfonate
pyruvate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
D-lactate + oxidized benzyl viologen
pyruvate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
D-lactate + oxidized carboxamido-methyl viologen
pyruvate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
D-ribonate + oxidized anthraquinone-2,6-disulfonate
D-erythro-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
D-ribonate + oxidized benzyl viologen
D-erythro-pent-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
D-ribonate + oxidized carboxamido-methyl viologen
D-erythro-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
D-xylonate + oxidized anthraquinone-2,6-disulfonate
D-threo-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
D-xylonate + oxidized benzyl viologen
D-threo-pent-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
D-xylonate + oxidized carboxamido-methyl viologen
D-threo-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
dimethylsulfoxide + oxidized antraquinone-2,6-disulfonate
dimethylsulfide + reduced antraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
galactarate + oxidized anthraquinone-2,6-disulfonate
2-oxogalactarate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
galactarate + oxidized benzyl viologen
2-oxogalactarate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
galactarate + oxidized carboxamido-methyl viologen
2-oxogalactarate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
indolylpyruvate + reduced benzyl viologen
2-hydroxy-3-indolylpropionate + oxidized benzyl viologen
indolylpyruvate + reduced methyl viologen
2-hydroxy-3-indolylpropionate + oxidized methyl viologen
L-arabinonate + oxidized anthraquinone-2,6-disulfonate
L-erythro-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
L-arabinonate + oxidized benzyl viologen
L-erythro-pent-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
L-arabinonate + oxidized carboxamido-methyl viologen
L-erythro-pent-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
L-arabinuronate + oxidized anthraquinone-2,6-disulfonate
? + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
L-arabinuronate + oxidized benzyl viologen
? + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
L-arabinuronate + oxidized carboxamido-methyl viologen
? + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
L-mannonate + oxidized anthraquinone-2,6-disulfonate
L-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
L-mannonate + oxidized benzyl viologen
L-arabino-hex-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
L-mannonate + oxidized carboxamido-methyl viologen
L-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
lactate + oxidized acceptor
pyruvate + reduced acceptor
-
Substrates: -
Products: -
Products: -
r
lactobionate + oxidized anthraquinone-2,6-disulfonate
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
-
Substrates: -
Products: -
Products: -
r
lactobionate + oxidized benzyl viologen
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced benzyl viologen
-
Substrates: -
Products: -
Products: -
r
lactobionate + oxidized carboxamido-methyl viologen
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
-
Substrates: -
Products: -
Products: -
r
mandelate + oxidized acceptor
oxo(phenyl)acetic acid + reduced acceptor
-
Substrates: -
Products: -
Products: -
r
N-acetylneuraminate + oxidized 1,1'-carbamoyl methyl viologen
? + reduced 1,1'-carbamoyl methyl viologen
-
Substrates: anaerobic conditions
Products: -
Products: -
r
pantolactone + oxidized acceptor
dehydropantolactone + reduced acceptor
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced 1,1'-carbamoyl methyl viologen
phenyllactate + oxidized 1,1'-carbamoyl methyl viologen
-
Substrates: anaerobic conditions
Products: -
Products: -
r
phenylpyruvate + reduced benzyl viologen
(2R)-phenyllactate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced benzyl viologen
2-hydroxy-3-phenylpropionate + oxidized benzyl viologen
phenylpyruvate + reduced benzyl viologen
phenyllactate + oxidized benzyl viologen
-
Substrates: anaerobic conditions
Products: -
Products: -
r
phenylpyruvate + reduced carbamoylmethyl viologen
(2R)-phenyllactate + oxidized carbamoylmethyl viologen
phenylpyruvate + reduced cobalt sepulchrate
(2R)-phenyllactate + oxidized cobalt sepulchrate
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced indigocarmine
(2R)-phenyllactate + oxidized indigocarmine
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced kresyl violet
(2R)-phenyllactate + oxidized kresyl violet
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced meldolablue
(2R)-phenyllactate + oxidized meldolablue
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced methyl viologen
2-hydroxy-3-phenylpropionate + oxidized methyl viologen
phenylpyruvate + reduced methylene blue
(2R)-phenyllactate + oxidized methylene blue
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced phenosafranine
(2R)-phenyllactate + oxidized phenosafranine
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced safranine TH
(2R)-phenyllactate + oxidized safranine TH
-
Substrates: -
Products: -
Products: -
r
(S)-2-oxo-3-methylpentanoate + reduced benzyl viologen
2-hydroxy-3-methylpentanoate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
(S)-2-oxo-3-methylpentanoate + reduced benzyl viologen
2-hydroxy-3-methylpentanoate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
(S)-2-oxo-3-methylpentanoate + reduced methyl viologen
2-hydroxy-3-methylpentanoate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
(S)-2-oxo-3-methylpentanoate + reduced methyl viologen
2-hydroxy-3-methylpentanoate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxo-3,3-dimethyl-4-hydroxybutanoate + reduced benzyl viologen
3,3-dimethyl-2,4-dihydroxybutanoate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxo-3,3-dimethyl-4-hydroxybutanoate + reduced benzyl viologen
3,3-dimethyl-2,4-dihydroxybutanoate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxo-3,3-dimethyl-4-hydroxybutanoate + reduced methyl viologen
3,3-dimethyl-2,4-dihydroxybutanoate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxo-3,3-dimethyl-4-hydroxybutanoate + reduced methyl viologen
3,3-dimethyl-2,4-dihydroxybutanoate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate + reduced benzyl viologen
2-hydroxyglutarate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate + reduced benzyl viologen
2-hydroxyglutarate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate + reduced methyl viologen
2-hydroxyglutarate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
2-oxoglutarate + reduced methyl viologen
2-hydroxyglutarate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
3-fluoropyruvate + reduced benzyl viologen
3-fluoro-2-hydroxypropionate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
3-fluoropyruvate + reduced benzyl viologen
3-fluoro-2-hydroxypropionate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
3-fluoropyruvate + reduced methyl viologen
3-fluoro-2-hydroxypropionate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
3-fluoropyruvate + reduced methyl viologen
3-fluoro-2-hydroxypropionate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
a (2R)-hydroxy-carboxylate + acceptor
a 2-oxo-carboxylate + reduced acceptor
-
Substrates: -
Products: -
Products: -
?
a (2R)-hydroxy-carboxylate + acceptor
a 2-oxo-carboxylate + reduced acceptor
-
Substrates: -
Products: -
Products: -
?
indolylpyruvate + reduced benzyl viologen
2-hydroxy-3-indolylpropionate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
indolylpyruvate + reduced benzyl viologen
2-hydroxy-3-indolylpropionate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
indolylpyruvate + reduced methyl viologen
2-hydroxy-3-indolylpropionate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
indolylpyruvate + reduced methyl viologen
2-hydroxy-3-indolylpropionate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
phenylglyoxylate + reduced benzyl viologen
(R)-mandelic acid
-
Substrates: -
Products: -
Products: -
?
phenylglyoxylate + reduced benzyl viologen
(R)-mandelic acid
-
Substrates: -
Products: -
Products: -
?
phenylglyoxylate + reduced methyl viologen
(R)-mandelic acid
-
Substrates: -
Products: -
Products: -
?
phenylglyoxylate + reduced methyl viologen
(R)-mandelic acid
-
Substrates: -
Products: -
Products: -
?
phenylpyruvate + reduced benzyl viologen
2-hydroxy-3-phenylpropionate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
phenylpyruvate + reduced benzyl viologen
2-hydroxy-3-phenylpropionate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
phenylpyruvate + reduced carbamoylmethyl viologen
(2R)-phenyllactate + oxidized carbamoylmethyl viologen
-
Substrates: -
Products: -
Products: -
?
phenylpyruvate + reduced carbamoylmethyl viologen
(2R)-phenyllactate + oxidized carbamoylmethyl viologen
-
Substrates: -
Products: -
Products: -
r
phenylpyruvate + reduced methyl viologen
2-hydroxy-3-phenylpropionate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
phenylpyruvate + reduced methyl viologen
2-hydroxy-3-phenylpropionate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
pyruvate + reduced benzyl viologen
lactate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
pyruvate + reduced benzyl viologen
lactate + oxidized benzyl viologen
-
Substrates: -
Products: -
Products: -
?
pyruvate + reduced methyl viologen
lactate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
pyruvate + reduced methyl viologen
lactate + oxidized methyl viologen
-
Substrates: -
Products: -
Products: -
?
additional information
?
-
-
Substrates: broad substrate specificity, stereochemic specificity, no activity with 3-oxoglutarate and hydroxyacetone
Products: -
Products: -
?
additional information
?
-
-
Substrates: product determination, stereochemistry and molecule conformations, products appear in pyranose, furanose or lactone form, overview
Products: -
Products: -
?
additional information
?
-
-
Substrates: 2-oxo acids with diverse substituents, e.g. carboxy, methyl, ethyl, halogen, methoxy, thiomethyl, NHCHO, unbranched and branched alkyl, OH-containing residues in 3-position, double bonds containing residues, substituents with additional CO groups, -OOC(CH2)n with n being at least 3, overview
Products: -
Products: -
?
additional information
?
-
-
Substrates: broad substrate specificity, stereochemic specificity, no activity with 3-oxoglutarate and hydroxyacetone
Products: -
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
molybdenum cofactor
-
mononucleotide, 1 enzyme molecule contains 1 molybdenum atom
additional information
-
enzyme contains iron sulfur clusters, with four iron and 4 sulfur atoms per enzyme molecule, enzyme belongs to the group of molybdoenzymes which possess no further prosthetic group than the iron sulfur clusters
-
additional information
-
neither NADH nor NADPH are cosubstrates for the enzyme, no flavin or heme cofactors
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Molybdenum
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
additional information
-
highest activity in potassium phosphate buffer compared to Tris-buffer, MOPS, Pipes or diphosphate buffer
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
additional information
-
production rates of D-(S)-chloroacetic acid by enzymatic and chemical or eletrochemical methods
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
8.5
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
25
37
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pI VALUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
additional information
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
Highest Expressing Human Cell Lines
Cell Line LinksPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
600000
80000
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
22
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-16°C, N2-atmosphere, wet packed cells, 450 days, more than 90% remaining activity
-
room temperature, freeze dried cells, 200 days, more than 80% remaining activity
-
room temperature, freeze dried cells, loss of 10% of activity within 1-2 years
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
APPLICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
biotechnology