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EC unknown
Synonyms
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membrane-bound quinoprotein inositol dehydrogenase
PQQ-dependent inositol dehydrogenase
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membrane-bound quinoprotein inositol dehydrogenase
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membrane-bound quinoprotein inositol dehydrogenase
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QIDH
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myo-inositol + pyrroloquinoline quinone = 2,4,6/3,5-pentahydroxycyclohexanone + pyrroloquinoline quinol
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myo-inositol:quinone 2-oxidoreductase
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allo-inositol + 2,6-dichlorophenol indophenol
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Substrates: i.e. 1,2,3,4/5,6-cyclohexanehexol
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D-sorbitol + 2,6-dichlorophenol indophenol
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Substrates: -
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muco-inositol + 2,6-dichlorophenol indophenol
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Substrates: i.e. 1,2,4,5/3,6-cyclohexanehexol
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myo-inositol + 2,6-dichlorophenol indophenol
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Substrates: -
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additional information
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Substrates: substrate specificity, overview
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pyrroloquinoline quinone
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dependent on
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additional information
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D-glucose suppresses the enzyme, D-mannitol suppresses enzyme induction by myo-inositol, overview
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additional information
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myo-inositol induces the enzyme maximally at 33 mM, but is slightly suppressing at higher concentrations, allo-inositol, muco-inositol, and D-sorbitol also induces the enzyme, D-mannitol suppresses enzyme induction by myo-inositol, overview
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0.09
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D-sorbitol induced wild-type strain, crude extract
0.6
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membrane fraction of induced wild-type cells
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strain ATCC 621H, DSM 2343, gene GOX1857
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bound
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Highest Expressing Human Cell Lines
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additional information
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construction of a GOX1857 disruption mutant strain DW1, which is inactive with myo-inositol and unable to grow with myo-inositol as the sole energy source
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gene GOX1857, DNA and amino acid sequence determination and analysis, expression of wild-type and mutant enzymes in Escherichia coli
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Hoelscher, T.; Weinert-Sepalage, D.; Goerisch, H.
Identification of membrane-bound quinoprotein inositol dehydrogenase in Gluconobacter oxydans ATCC 621H
Microbiology
153
499-506
2007
Gluconobacter oxydans
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