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The enzyme from the bacterium Gluconobacter oxydans acts on polyols with a D-lyxo configuration, such as D-mannitol and D-sorbitol, with preference towards the former.
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The enzyme appears in viruses and cellular organisms
polyol dehydrogenase, more
D-mannitol + a ferricytochrome c = D-fructose + a ferrocytochrome c + 2 H+
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