Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
The enzyme appears in viruses and cellular organisms
Synonyms
mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase, more
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(R)-mevalonate + NADP+ = mevaldate + NADPH + H+
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(R)-mevalonate:NADP+ oxidoreductase
May be identical with EC 1.1.1.2 [alcohol dehydrogenase (NADP+)].
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(3RS)-mevaldate + NADPH + H+
(R)-mevalonate + NADP+
-
Substrates: -
Products: -
r
(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH
(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+
-
Substrates: -
Products: -
ir
(S)-3-hydroxy-3-methyl-5-oxovaleric acid + NADH
(S)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NAD+
-
Substrates: -
Products: -
ir
4-cyanobenzaldehyde + NADPH
4-cyanobenzylalcohol + NADP+
-
Substrates: -
Products: -
ir
pyridine-3-carboxaldehyde + NADPH
pyridine-3-methanol + NADP+
-
Substrates: -
Products: -
ir
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(R)-3-hydroxy-3-methyl-5-oxovaleric acid + NADPH
(R)-3-hydroxy-3-methyl-5-hydroxyvaleric acid + NADP+
-
Substrates: -
Products: -
ir
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NADH
-
giving one-fifth of the rate obtained with NADPH
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Sodium aminobarbitone
-
1 mM, 48% inhibition, noncompetitive
Thiobarbituric acid
-
1 mM, 22% inhibition, noncompetitive
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.15
4-cyanobenzaldehyde
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
brenda
Highest Expressing Human Cell Lines
Cell Line Links
Gene Links
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
AK1A1_MOUSE
325
0
36587
Swiss-Prot
other Location (Reliability: 3)
AK1A1_PIG
325
0
36582
Swiss-Prot
other Location (Reliability: 3)
AK1A1_PONAB
325
0
36390
Swiss-Prot
other Location (Reliability: 3)
AK1A1_RAT
325
0
36506
Swiss-Prot
other Location (Reliability: 3)
AK1A1_BOVIN
325
0
36617
Swiss-Prot
other Location (Reliability: 3)
AK1A1_CRIGR
324
0
36510
Swiss-Prot
other Location (Reliability: 3)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-20°C, 3 months, 0% loss of activity
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ammonium sulfate precipitation, calcium phosphate gel, gel filtration
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Beedle, A.S.; Rees, H.H.; Goodwin, T.W.
Some properties and a suggested reclassification of mevaldate reductase
Biochem. J.
139
205-209
1974
Sus scrofa
brenda
html completed