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BRENDA support

Information on EC 1.1.1.280 - (S)-3-hydroxyacid-ester dehydrogenase

for references in articles please use BRENDA:EC1.1.1.280

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IUBMB Comments

Also acts on 4-oxo- and 5-oxo-fatty acids and their esters. cf. EC 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
  • 1.1.1.280
  • branched-chain
  • transaminase
  • glioblastoma
  • neoplasia
  • non-neoplastic
  • invasiveness
  • hypermethylation
  • synthesis

Synonyms
2-methyl-3-oxobutanoate reductase, 3-oxo ester (S)-reductase, EC 1.2.1.56, reductase, 3-oxo ester (S)-, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ethyl (S)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + NADPH + H+
show the reaction diagram
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