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Information on EC 1.1.1.279 - (R)-3-hydroxyacid-ester dehydrogenase

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IUBMB Comments
Also acts on ethyl (R)-3-oxobutanoate and some other (R)-3-hydroxy acid esters. The (R)- symbol is allotted on the assumption that no substituents change the order of priority from O-3 > C-2 > C-4. A subunit of yeast fatty acid synthase EC 2.3.1.86 fatty-acyl-CoA synthase). cf. EC 1.1.1.280 (S)-3-hydroxyacid ester dehydrogenase.
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The expected taxonomic range for this enzyme is: Saccharomyces cerevisiae
Synonyms
EC 1.2.1.55, reductase, 3-oxo ester (R)-, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ethyl (R)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + NADPH + H+
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