Information on EC 1.1.1.27 - L-lactate dehydrogenase and Organism(s) Gallus gallus

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea


The taxonomic range for the selected organisms is: Gallus gallus

EC NUMBER
COMMENTARY hide
1.1.1.27
-
RECOMMENDED NAME
GeneOntology No.
L-lactate dehydrogenase
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Bifidobacterium shunt
-
-
heterolactic fermentation
-
-
pyruvate fermentation to lactate
-
-
superpathway of glucose and xylose degradation
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-
L-lactaldehyde degradation
-
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lactate fermentation
-
-
Glycolysis / Gluconeogenesis
-
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Cysteine and methionine metabolism
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Pyruvate metabolism
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Propanoate metabolism
-
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Metabolic pathways
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Biosynthesis of secondary metabolites
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Microbial metabolism in diverse environments
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Biosynthesis of antibiotics
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-
SYSTEMATIC NAME
IUBMB Comments
(S)-lactate:NAD+ oxidoreductase
Also oxidizes other (S)-2-hydroxymonocarboxylic acids. NADP+ also acts, more slowly, with the animal, but not the bacterial, enzyme.
CAS REGISTRY NUMBER
COMMENTARY hide
9001-60-9
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-fluoropyruvate + NADH
?
show the reaction diagram
-
-
-
-
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pyruvate + NADH + H+
(S)-lactate + NAD+
show the reaction diagram
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NADH
-
coenzyme
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
16
3-acetylpyridine adenine dinucleotide
-
enzyme form heart and muscle
98
Fluoropyruvate
-
-
3.3 - 60
NAD+
1.1
nicotinamide hypoxanthine dinucleotide
-
enzyme from muscle
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
PDB
SCOP
CATH
UNIPROT
ORGANISM
P00337
Gallus gallus;