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Information on EC 1.1.1.238 - 12beta-hydroxysteroid dehydrogenase

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IUBMB Comments
Acts on a number of bile acids, both in their free and conjugated forms.
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The expected taxonomic range for this enzyme is: Clostridium paraputrificum
Synonyms
12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3alpha,7alpha,12beta-trihydroxy-5beta-cholan-24-oate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oate + NADPH + H+
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