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Information on EC 1.1.1.231 - 15-hydroxyprostaglandin-I dehydrogenase (NADP+)

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IUBMB Comments
Specific for prostaglandin I2.
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The enzyme appears in viruses and cellular organisms
Synonyms
dehydrogenase, prostacyclin, NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase, NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase, PG I2 dehydrogenase, prostacyclin dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-6,9alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate + NADPH + H+
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