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IUBMB CommentsNADP+ can also act, but more slowly. Involved in the biosynthesis of (+)-3-thujone and (-)-3-isothujone.
The enzyme appears in viruses and cellular organisms
Synonyms
(+)-cis-sabinol dehydrogenase, EC 1.1.1.182,
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(+)-cis-sabinol dehydrogenase
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EC 1.1.1.182
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formerly, part transferred
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(+)-cis-sabinol + NAD+ = (+)-sabinone + NADH + H+
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(+)-cis-sabinol:NAD+ oxidoreductase
NADP+ can also act, but more slowly. Involved in the biosynthesis of (+)-3-thujone and (-)-3-isothujone.
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(+)-cis-sabinol + NAD+
(+)-sabinone + NADH
(+)-cis-sabinol + NAD+
(+)-sabinone + NADH
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(+)-cis-sabinol + NAD+
(+)-sabinone + NADH
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pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
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(+)-cis-sabinol + NAD+
(+)-sabinone + NADH
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(+)-cis-sabinol + NAD+
(+)-sabinone + NADH
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pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
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?
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(+)-cis-sabinol + NAD+
(+)-sabinone + NADH
(+)-cis-sabinol + NAD+
(+)-sabinone + NADH
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pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
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(+)-cis-sabinol + NAD+
(+)-sabinone + NADH
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pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
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?
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NAD+
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NADP+
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65-85% as effective as NAD+
NADP+
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65-85% as effective as NAD+
additional information
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flavin nucleotides are ineffective
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additional information
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flavin nucleotides are ineffective
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sage
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brenda
tansy
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brenda
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oil glands
brenda
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oil glands
brenda
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stable to lyophilization
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stable to lyophilization
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-40C, lyophilized, under argon, stable for several months without deterioration
-40C, lyophilized, under argon, stable for several months without deterioration
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-40C, lyophilized, under argon, stable for several months without deterioration
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partial
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Dehal, S.S.; Croteau, R.
Metabolism of monoterpenes: Specificity of the dehydrogenases responsible for the biosynthesis of camphor, 3-thujone, and 3-isothujone
Arch. Biochem. Biophys.
258
287-291
1987
Salvia officinalis, Tanacetum vulgare
brenda
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1.1.1.228 (+)-sabinol dehydrogenase
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