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The enzyme from Corynebacterium cyclohexanicum is highly specific for the trans-4-hydroxy derivative.
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The enzyme appears in viruses and cellular organisms
trans-4-hydroxycyclohexanecarboxylate dehydrogenase, more
trans-4-hydroxycyclohexanecarboxylate + NAD+ = 4-oxocyclohexanecarboxylate + NADH + H+
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