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EC 1.14.13.7 Details
EC number
1.14.13.7
Accepted name
phenol 2-monooxygenase (NADPH)
Reaction
phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O
Other name(s)
phenol hydroxylase, phenol o-hydroxylase
Systematic name
phenol,NADPH:oxygen oxidoreductase (2-hydroxylating)
CAS registry number
37256-84-1
Comment
A flavoprotein (FAD). The enzyme from the fungus Trichosporon cutaneum has a broad substrate specificity, and has been reported to catalyse the hydroxylation of a variety of substituted phenols, such as fluoro-, chloro-, amino- and methyl-phenols and also dihydroxybenzenes. cf. EC 1.14.14.20, phenol 2-monooxygenase (FADH2).
History
created 1972, modified 2011, modified 2016
EC Tree
1.14.13.45 created 1992, deleted 2003