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EC 1.14.13.25 Details
EC number
1.14.13.25
Accepted name
methane monooxygenase (soluble)
Reaction
methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O
Other name(s)
methane hydroxylase
Systematic name
methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)
CAS registry number
51961-97-8
Comment
The enzyme is soluble, in contrast to the particulate enzyme, EC 1.14.18.3. Broad specificity; many alkanes can be hydroxylated, and alkenes are converted into the corresponding epoxides; CO is oxidized to CO2, ammonia is oxidized to hydroxylamine, and some aromatic compounds and cyclic alkanes can also be hydroxylated, but more slowly.
History
created 1984, modified 2011
EC Tree
1.14.13.45 created 1992, deleted 2003