EC 1.1.99.B12: littorine mutase/monooxygenase
This is an abbreviated version!
For detailed information about littorine mutase/monooxygenase, go to the full flat file.
Reaction
Synonyms
CYP80F1
ECTree
1.1.99.B12 littorine mutase/monooxygenaseAdvanced search results
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results (| Results | in table |
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| 1 | AA Sequence |
| 1 | Cloned(Commentary) |
| 1 | Cofactor |
| 2 | General Information |
| 1 | Organism |
| 1 | Reaction |
| 1 | Reference |
| 1 | Source Tissue |
| 3 | Substrates and Products (Substrate) |
| 1 | Synonyms |
| 1 | Systematic Name |
Substrates Products
Substrates Products on EC 1.1.99.B12 - littorine mutase/monooxygenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY 
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(R)-littorine + acceptor
3'-hydroxylittorine + reduced acceptor
Substrates: expression in yeast confirms that CYP80F1 catalyzes the oxidation of (R)-littorine with rearrangement to form hyoscyamine aldehyde, a putative precursor to hyoscyamine, and without rearrangement to form 3'-hydroxylittorine
Products: -
Products: -
?
(R)-littorine + acceptor
hyoscyamine aldehyde + reduced acceptor
Substrates: expression in yeast confirms that CYP80F1 catalyzes the oxidation of (R)-littorine with rearrangement to form hyoscyamine aldehyde, a putative precursor to hyoscyamine, and without rearrangement to form 3'-hydroxylittorine
Products: -
Products: -
?
(S)-littorine + acceptor
(2'S,3'S)-3'-hydroxylittorine + (2'S,3'R)-3'-hydroxylittorine + ?
Substrates: products are (2'S,3'S)-3'-hydroxylittorine, and a minor amount of (2'S,3'R)-3'-hydroxylittorine
Products: -
Products: -
?
