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BRENDA support

EC 1.1.1.441: polyprenol dehydrogenase [NAD(P)H]

This is an abbreviated version!
For detailed information about polyprenol dehydrogenase [NAD(P)H], go to the full flat file.

Reaction

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a ditrans,polycis-polyprenol
+
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NAD(P)+
=
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a ditrans,polycis-polyprenal
+
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NAD(P)H
+
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H+

Synonyms

chDHRSX, DHRSX, dolichal reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.4411.1.1.441 polyprenol dehydrogenase [NAD(P)H]

Reference

Reference on EC 1.1.1.441 - polyprenol dehydrogenase [NAD(P)H]

Please use the Reference Search for a specific query.

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wilson, M.P.; Kentache, T.; Althoff, C.R.; Schulz, C.; de Bettignies, G.; Mateu Cabrera, G.; Cimbalistiene, L.; Burnyte, B.; Yoon, G.; Costain, G.; Vuillaumier-Barrot, S.; Cheillan, D.; Rymen, D.; Rychtarova, L.; Hansikova, H.; Bury, M.; Dewulf, J.P.; Caligiore, F.; Jaeken, J.; Cantagrel, V.; Va, V.a.n.
A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis
Cell
187
3585-3601.e22
2024
Homo sapiens (Q8N5I4)
Manually annotated by BRENDA team
Kentache, T.; Althoff, C.R.; Caligiore, F.; Souche, E.; Schulz, C.; Graff, J.; Pieters, E.; Stanley, P.; Contessa, J.N.; Van Schaftingen, E.; Matthijs, G.; Foulquier, F.; Bommer, G.T.; Wilson, M.P.
Absence of the dolichol synthesis gene DHRSX leads to N-glycosylation defects in Lec5 and Lec9 Chinese hamster ovary cells
J. Biol. Chem.
300
107875
2024
Cricetulus griseus
Manually annotated by BRENDA team