EC 1.1.1.291: 2-hydroxymethylglutarate dehydrogenase
This is an abbreviated version!
For detailed information about 2-hydroxymethylglutarate dehydrogenase, go to the full flat file.
Reaction
Synonyms
HgD
ECTree
1.1.1.291 2-hydroxymethylglutarate dehydrogenaseAdvanced search results
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results (| Results | in table |
|---|---|
| 1 | AA Sequence |
| 1 | Cloned(Commentary) |
| 2 | Cofactor |
| 2 | KM Value [mM] |
| 1 | Molecular Weight [Da] |
| 1 | Natural Substrates/ Products (Substrates) |
| 1 | Organism |
| 1 | Oxidation Stability |
| 3 | Pathway |
| 4 | PDB ID |
| 1 | Purification (Commentary) |
| 1 | Reaction |
| 1 | Reference |
| 2 | Substrates and Products (Substrate) |
| 1 | Subunits |
| 1 | Synonyms |
| 1 | Systematic Name |
Systematic Name
Systematic Name on EC 1.1.1.291 - 2-hydroxymethylglutarate dehydrogenase
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SYSTEMATIC NAME 
IUBMB Comments
(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase
NADP+ cannot replace NAD+. Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri. Other enzymes involved in this pathway are EC 1.17.1.5 (nicotinate dehydrogenase), EC 1.3.7.1 (6-hydroxynicotinate reductase), EC 3.5.2.18 (enamidase), EC 5.4.99.4 (2-methyleneglutarate mutase), EC 5.3.3.6 (methylitaconate Delta-isomerase), EC 4.2.1.85 (dimethylmaleate hydratase) and EC 4.1.3.32 (2,3-dimethylmalate lyase).
