EC 1.1.1.231: 15-hydroxyprostaglandin-I dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about 15-hydroxyprostaglandin-I dehydrogenase (NADP+), go to the full flat file.

Reaction

Show molfile — (5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate

Synonyms

dehydrogenase, prostacyclin, NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase, NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase, PG I2 dehydrogenase, prostacyclin dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)

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All data fields related to EC 1.1.1.231
Results	in table
1	CAS Registry Number
2	Cloned(Commentary)
4	Cofactor
1	General Stability
2	Inhibitors
7	KM Value [mM]
8	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
7	Organism
2	Pathway
2	pH Optimum
1	Posttranslational Modification
3	Purification (Commentary)
2	Reaction
3	Reaction Type
7	Reference
6	Source Tissue
7	Specific Activity [micromol/min/mg]
1	Storage Stability
19	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Molecular Weight

Molecular Weight on EC 1.1.1.231 - 15-hydroxyprostaglandin-I dehydrogenase (NADP+)

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28000

Oryctolagus cuniculus

2 * 28000, rabbit, SDS-PAGE

348013

31000

Macaca fascicularis

SDs-PAGE of recombinant enzyme

348015

34000

Cricetulus griseus

SDS-PAGE of recombinant forms CHCR1, CHCR2 including His-tag

348016

56000

Oryctolagus cuniculus

SDS-PAGE of amidinated enzyme

348013

62000

Oryctolagus cuniculus

gel filtration

348012

additional information

3 entries