>Q9Y9J0|hydroxymethylbilane synthase|EC 2.5.1.61|Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)|Swiss-Prot
MRVRVAARGSRLSLLQVEQALEELSRYAGVSMHWEVVRVKSAGDVWSDRPLESIGVVGVF
TREVDRAVASGAADIAVHSLKDMPTSGYGGPLKIVYIASRPSARDALISRQGPGRVEDLE
PGSTLGTSSARRRALSLHYNPRIRVENLRGNLDTRLRKLREGLYDAIIASEAGLIRLGVD
VEYTPLDPSYFPPAPGQGFVAVVARVGSNVEKMLRDLDKPPWWHVAWAERGVLEGARAGC
RTPVAAYAEPLGRSMVRVTAAALSPDGSRAYWARAEGRIEEARRIGVSLGEELSRVVEGW
HKTGGGS
>A8FFV2|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus pumilus (strain SAFR-032)|Swiss-Prot
MRTIKVGSRRSKLAITQTKWVIQKLSELNPSYSFEIKEIVTKGDQILDVTLSKVGGKGLF
VKEIEQAMLNHDIDMAVHSMKDMPAALPEGLVIGCIPEREDVRDALISKDHLHLHELPKG
AIVGTSSLRRSAQLLQERPDLNIKWIRGNIDTRLEKLKNEEYDAIILAAAGLSRMGWSKE
VVSEFLSPETCLPAVGQGALSIECRGDDEELLQLLAQFTNEYTKKTVLAERAFLKQMDGS
CQVPIAGYATMNERDEIELTGLVASADGHTIIRETVSGTDPEAIGTACAKQMADKGAKDL
IDKVKKDLSSQ
>Q62LC0|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei (strain ATCC 23344)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>Q9PK95|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia muridarum (strain MoPn / Nigg)|Swiss-Prot
MLSAYYNDPFLSDFCLGKIPLRLASRKSPLAVLQAHECLRRLQTFFPRLWGQVITETTQG
DLDQHTPLHSVENTGFFTDDIDFLVQSGKCDLAIHSAKDLPEKPKARVIAITASIDPRDI
LVFQEKYLLQPFPSRLRIGCSSDRRRALISSLYPSAVITDIRGTIQTRLALLDQQKFDAI
VMANAAVSRLGLRLPCTVVLPPPYHPFQGRLAITSCHHIASWEKLFLTCKITENINLLHF
FS
>C3PKG2|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1)|Swiss-Prot
MLKIGTRGSLLATTQSGHVQEWLQQKGYEAELHIVTTQGDVNMAPVERIGVGVFTQALRE
AVDRGECEIAVHSFKDLPTAADERFDLVVPQRQDVREALIARDGLTLKELPEGARVGTSA
PRRISQLRAMRPDLDIRPLRGNIDTRMGKVTSGELDAVLLAYAGLVRAGYAERATEVFDP
EVFMPAPAQGALAIEAVKGTEAAKAIALLADGPATAATRAERTVLSQLEAGCTAPVAATS
HWEGEQLVVRGGVFALDGSRQLIAQAQGAASEAEELGRAVSKELFAQGAADVLAAE
>B7L959|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain 55989 / EAEC)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A4IZY4|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. tularensis (strain WY96-3418)|Swiss-Prot
MKQITIASRESKLALWQTNFIKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>Q5QUS3|hydroxymethylbilane synthase|EC 2.5.1.61|Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)|Swiss-Prot
MTQRVRIATRKSKLALWQAEHIQQRLEELHPGLSVELVPMSTKGDVILDTPLAKIGGKGL
FVKELEVAMLEGRADIAVHSMKDLPVEFPPGLELHTICEREDPRDAFVSNNYKNLNELPE
GAVVGTCSLRRRCQVKEQFPHLVIKDLRGNVQTRLRKLDEGEFDAIILAASGLIRLELGD
RITSFIPVEQSLPANGQGALGIECRSDDDEMKALLAPLQCQETRTRVLAERAMNRGLDGG
CQVPIGAYAELEGDEVYLRGLVGEPDGGKVLRDEVRGPASKAEELGSELAERLLKQGAAE
ILSAVYDSESSHS
>Q8TXC8|hydroxymethylbilane synthase|EC 2.5.1.61|Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)|Swiss-Prot
MSETIRVATRSSRLAIIQTREVIELLERESPRDVEVEIVKTKSRGDVVRDRPLHKLGEKG
VFVKEVDRLVLEGKADIAVHSAKDVPSVVDYPVDVAAVPPRRDPRECLVSRHGGLKELPR
GATVGTSSPRRRAQILLERPDLKVEPMRGNVDTRVSKVRRREYDAAVLAKVGLDRLGMTS
EVSEVYDPEEFVPPAGQGALMITCRKDDDRVKRLLEVVDDEKSRVEVETEKAVVRELGVG
CSEPVGVHVRARDGDHVRLVLGLFEEDGSCGHVLKMRGSPEDVVREAVSQAREVLSDG
>Q5YP70|hydroxymethylbilane synthase|EC 2.5.1.61|Nocardia farcinica (strain IFM 10152)|Swiss-Prot
MGAAATGTPLRIGTRGSLLAMTQAGTVRDALIAAGRPAELVVVKTPGDMSSDPVQKIGVG
VFTSALRDELAAGTIDLAVHSYKDLPTAPDPRFVIAAIPPREDPRDALVARDGLVLGELP
AGAKVGTSAPRRVAQLRALGLGLDIVPLRGNLDSRLARVTDGELDAVVVARAGLSRIGRT
AVITEALEPVQMLPAPAQGALAVECRSEDAALIEALAELDDAATRAAVVAERALLAELEA
GCTAPVGALAEVVESLDDDGRIVEELSLRGCAAAVDGSEVLRASVVGDPERAAELGRALA
RELLELGARELLVEVAATEPGARSGTGAVRPPETDLSNPSPMENPQ
>B4F1X3|hydroxymethylbilane synthase|EC 2.5.1.61|Proteus mirabilis (strain HI4320)|Swiss-Prot
MSKSTIRIATRQSPLAMWQALYVKEQLQIAHPSLVVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELALLSSRADIAVHSMKDVPIDFPEGLGLVTICEREDPRDAFVSNHYDSLEQLP
AGSVVGTSSLRRQCQLKALRPDLIIRDLRGNVGTRLSKLDNGDYDAIILAVAGLKRLKLT
ERIRSSLSAEQSLPAVGQGAVGIECRLDDHDTQALLAALNHADTATCVKAERAMNTRLEG
GCQVPIGSYAIWQNGKIWLRALVGSPDGETILRGERLVSPEDAEQAGISLAEELLDKGAR
EILTAVYQGNTAI
>Q92LH7|hydroxymethylbilane synthase|EC 2.5.1.61|Rhizobium meliloti (strain 1021)|Swiss-Prot
MQTKPFRIGTRGSPLAMAQTHETRDRLAAAHGLPPEMFEIVILSTKGDRITDRSLAEIGG
KGLFTEELEQQLLSGDLDFAVHSSKDMPTKLPEGLFLSAFLPREDIRDAFVGRSAKRLVD
LPQGATVGSSSLRRQALIRRLRPDIDVITYRGQVETRLRKLAEGQVDGTLLAYAGLRRLG
MEHVPTELLDPEEFPPAPAQGAICVEARIGDDRINTLLAAIDDPRTHEAVSCERGFLATL
DGSCRTPIAGYAQSDGTHIRFAGMILTPDGTTSHQIEIDGRAADAERLGQEAGERIRAKA
GPGFFSSWS
>B8E879|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella baltica (strain OS223)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLDDLADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELP
LGATVGTSSLRRQCQIRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRINDERVKALLAPLEHLETRYRVLAERAMNTRLEG
GCQVPIGAFAEIDGDEMTLRGLVGNPDGSEIIEGVITGPKTEATQLGVALAEELLSKGAK
SILDAVYAKA
>A8Z2J1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain USA300 / TCH1516)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q9HKM5|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)|Swiss-Prot
MITIRIGTRPSRLAVRQAEIVASAIRHAGYEVEIVKYRSEGDSDLKSPLYSIGKTGVFVE
RLNSLILSGDIDAAVHSAKDIPYEIDRRLRISAVMPRGRFEDALVSENPLSKLPPGSVIG
TSSLRRRYQILYQRKDVKVSNIRGNVDTRIEKMRSEGMAGIVMALAAIDRLELNLRYWPF
DPEKFVPAPNQGIIAVVSEDGSKASEVLSSINDADTYDDMMAERSITQGLKLGCSTPVGI
LSRHTGKGMRILAQFFAMDGSDMMMFDQHVDGLDDVDGIVSYIRENLPEEYGYKL
>B2I5K8|hydroxymethylbilane synthase|EC 2.5.1.61|Xylella fastidiosa (strain M23)|Swiss-Prot
MPLLRIATRKSLLAMWQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIG
ARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQR
MTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRKCVIAERTMNRALHGSC
HVPVGAYASYEVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAEL
LAATA
>C3L6Z5|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus anthracis (strain CDC 684 / NRRL 3495)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>Q2YLM5|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella abortus (strain 2308)|Swiss-Prot
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDVLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>A0RNT3|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter fetus subsp. fetus (strain 82-40)|Swiss-Prot
MNIKIASRNSALALWQTHHIRDLLIAQGHSVEIITMKTKGDVILDTPLAKIGGKGLFTKE
LENSMLEGSADIAVHSLKDVPTTFPDGLKLACVCSREDVRDAMLSMKYKNLDELPQGAKV
GTTSLRRKMQILAHRADLDIISLRGNVNSRIAKLKNGEFDAIILAMAGINRLNLSKEVKF
TSAIDTIPAMGQGALGIEAIDKKEILDAIEFLNDEKSVVETTIERDFVHTLNGGCQAPIG
INAKLKGDKIEVEAILGLVDGSEILRDSKTYPKLAYKIAGKNFADEFIARGAKELLKRAE
EMV
>B2TPD7|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain Eklund 17B / Type B)|Swiss-Prot
MNELIIATRKSKLAQVQTEIIMGKLKSKFNIDSKKLLIVTEGDRKLDVSLNKIGGKGLFV
KDIELALLNKEAHAAVHSMKDVPFEVSSEFEITAITGREDIRDVFISNGDISFKDIKKGA
KVGTSSIRRAAQLKLLRSDLEIVPIRGNVQTRLKKMEEQNLDGIVLAAAGLKRLGDENLI
TDYFDPKEFLPAVSQGALGIECLKDGDANKYFEALIDAEATLTVEAERSFMKELQGDCHS
LIGAYSEIQGDDLYMIGIYDIGGKIVKKDILGCKTNNIELGKKLAQKILG
>C1CYD9|hydroxymethylbilane synthase|EC 2.5.1.61|Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923)|Swiss-Prot
MRTVTVGTRGSTLALAQTRWVVARLKEEWPDTDFRIQTISTKGDRNRESLEAMAQKGDKG
FWVKEIEDALLQKRIDIAVHSLKDLPTEQPEGLEVASIPKRVDARDVLIGKEGMKRLADL
PQGARVGTSSVRRKAFLRAYRPDLQVIDLRGNIDTRLAALAGDEYDAIILAAAGLIRTEM
RHRIDEFVEPDILLPAPGQGALALETRSGPENDLTIEVAYAIHDHGTDDRITAEREFLAG
LGAGCMAPVGAHASIKGGVLTLEGWVGALDGSKVIRATSIGDPAECADIGAELAGDMLGQ
GAQALIDAARE
>P40129|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia chrysanthemi|Swiss-Prot
MVDTILRIATRQSPLALWQAHFVQQRLEACHPGLRVELVPMVTRGXLLLDTPLAKVGGKG
LFVKELELALLENRADIAVHSMKDVPVEF
>B0UWZ8|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus somnus (strain 2336)|Swiss-Prot
MSINKTLKIATRQSPLALWQANYVKNRLQQRYSHLSVELVPIITKGDVILDTPLAKIGGK
GLFVKELENALLNGEADIAVHSMKDVPMQFPKGLELSVICPREDPRDAFVSNKYRTLDEL
PQGAIVGTSSLRRQCQLKNWRADLDIRSLRGNVGTRLNKLDQGDYDAIILASAGLIRLGL
TERIRSFIEIDTILPACGQGAVGIECRVDDRDVQSLLMPLADQTTTYCVLAERAMNFHLQ
GGCQVPIGAYAILENNQLYLRGLVGDVHGSQILSAEGQFELSLDFESSQSAVQKAEELGV
SIAEQLLQQGADKILQAVYQS
>Q92BF8|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria innocua serovar 6a (strain CLIP 11262)|Swiss-Prot
MKRKIIVGSRRSKLALTQSNWVIKKLKENYPEIDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEVIDFAVHSMKDVPSSLKDGLVIGAIPKRESPLDCFVFNEVSTLDDLPK
GAVIGTSSLRRAAQLLKHRPDFVVKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTSLKLEDISPELCLPAVGQGALAIECRETDLQICDMLASIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATKTGDSVHFKGLVGNADGSIILESERTGASPAEIGNQVAEELLSEGAD
TIIKELRNI
>B2HRJ2|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium marinum (strain ATCC BAA-535 / M)|Swiss-Prot
MIRIGTRGSLLATTQAATVRDALIANGHAAELVTISTLGDRSSAPIETLGVGVFTTALRE
AIEDGRVDAAVHSHKDLPTAQDPRFTIAAIPPRQDPRDAVVARDGLVLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSNGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAIECRAGDSRLATVLAELDDADTRAAVTAERALLAELEAGCSAPVGA
IAEVVESIDEEGRVFEELSLRGCVAALDGSDVIRASGIGTSGRARELGLAVAAELFELGA
RELMWGEGNSPQGS
>B4SFI2|hydroxymethylbilane synthase|EC 2.5.1.61|Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1)|Swiss-Prot
MKKQLIIGTRSSPLALWQAEFTKAELSRHFPELDITLKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKHLITKEIDLAVHSLKDVPTATPDGLIITSFTEREDTRDVIISKNGVKLKDLPQ
NAKMATSSLRRMSQLLSLRPDLDIRDIRGNLNTRFQKFDNGEFDAMMLAYAGVFRLNFSD
RISEILPHEVMLPAVGQGALGIETRVDDEQTREIVRILNHSTTEYCCRAERALLRHLQGG
CQIPIGAYASFKNGTLTLLAYVGSVDGKIGLHNNITKTGLTSPEQAEAAGIELAEELLKQ
GADAILSQIRKTR
>C3K424|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas fluorescens (strain SBW25)|Swiss-Prot
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLKVSLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTYASLDALP
LGSIVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVEDSLPAGGQGAVGIECRTADSDIHALLKPLDHHDTEVRVTAERALNKHLNG
GCQVPIACYAVLEGENLWLRGLVGDPEGGNLLTAEVRGPQCDATALGIQVAQALLDKGAG
AILQKVYGEAGPQ
>A8GSI6|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia rickettsii (strain Sheila Smith)|Swiss-Prot
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>C3MYD9|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)|Swiss-Prot
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIIDIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLERDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNENIIP
>B5FF97|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio fischeri (strain MJ11)|Swiss-Prot
MSQQLPVRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQLKEARPDLIIKELRGNVGTRLQKLDDGNYDAIILACAGLIRLGL
EDRIKSAIEPEQSLPAVGQGAVGIEARLDDDRLRALLEPLNHPETANRVLCERAMNNRLE
GGCQVPIGSYSLIDGDQIWLRALVGEPDGSVMIRGEVSGPVSDAEALGTQLADQLLNDGA
KEILERLYAEA
>A4TRA8|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis (strain Pestoides F)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>Q82E76|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)|Swiss-Prot
MSEQALRLGTRRSKLAMAQSGQVADAVRQVTGRPVELVEITTYGDTSREHLAQIGGTGVF
VTALRDALLRGEVDFAVHSLKDLPTAQPDELALAAVPVREDPRDVLVARDGLTFEELGAP
SPKGTARVGTGSPRRMAQLNAYARSHGLAVETVPIRGNVDSRIGYVRSGELDGVVLAAAG
LHRIGRIDEVTEFLPVDTVLPAPGQGALAIECAADNADLIAALAELDDPFTRAAVTAERS
LLAALEAGCSAPVGALADLLADGQIVTEMRLRGVVGTTDGSTLVQLSTTGPVPETHDQAM
ALGRELAAEMLAKGAAGLMGEREH
>B7HE96|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain B4264)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDND
VITEHLDDTLCVPAVGQGALAIECREDDKDLLQLLAHINDTITERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTNPEEVGLEAADRLIKQGAKEL
ILAANKEQQ
>Q8FYI6|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella suis biovar 1 (strain 1330)|Swiss-Prot
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>B9KGA9|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060)|Swiss-Prot
MQLIIATRKSQLALWQSEYIKNKLSQTHSDLEISLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRGDSHLAVHSLKDVPSFFPKGLVLAAISKREEVNDAFLSEYYESLNALPKGA
KVGTTSLRRRMQLLALRPDLNIISLRGNINSRLEKLKAKEFDAIILAFAGIKRLGLEKQI
KFVKKFELDEMIPAASQGALGIESIDDKQILKYLECLNDKNAFVETHIERDFIKTLEGGC
QVPIGINAKIIDEKIEIRAIVGLPDASKILKEKRMIDKQDYAKAGELLAKEMIAKGAKEI
LKEAESMI
>Q180R9|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium difficile (strain 630)|Swiss-Prot
MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDLIQNVSLDKIGDKGLFV
KEIEQQLLDGKIDIAVHSMKDMPSYLANGLKFAHTPKREDPRDVLILREGYKNLDDLPHG
AVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDENMHGIVLAASGIIRANLQDK
ISSYLPVDVVIPAPAQGALAIEIRSNDSAIEGIVNSLKDENTEIQILAERGFLDGVNGSC
HIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDGDISSPRELGLKLAKLVLKEYENYE
G
>Q24VC8|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfitobacterium hafniense (strain Y51)|Swiss-Prot
MGSVKIGTRDSQLALWQAEWVKRKLEEYYPEREFVLVPMKTKGDKILDVPLAKIGDKGLF
TKELEVGLLNGEIDCAVHSLKDLPTVLPPGLEIAAFCEREEPRDVFLSKDGTPLGSLPAG
SIIGTSSLRRKAQLQNYRSDLSFADLRGNLQTRWRKLQESDMAGIVLAAAGVKRLGWEDR
ITEYISEEIMLSAVGQGAIAVEIAAQRADVREMLDLLNHGDTERAVKAERALLYRLEGGC
QIPIGAWAVTEQQQIVLKGMVASLDGQRILKVTLSGEHPEELGRQAADLLIAQGALEILQ
EIRTPLEK
>C4L4J6|hydroxymethylbilane synthase|EC 2.5.1.61|Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)|Swiss-Prot
MRKIIVGSRRSQLAMTQTKWVIEQLKQAGATNEFEIKEIVTKGDQIVDVQLSKVGGKGLF
VKEIQQQMLDGDIDFAVHSMKDVPAELPEELYISCMPKRVDARDVLICENGYTFETLPKG
SIVGTSSLRRGAQILAARPDLEIQWIRGNIDTRLKKLDSENYNAILLAKAGLERMGWTDR
VDFEALDPDVMVPAVGQGVLAIESRKDDAEVTTVLQLLHDDVTAKAATAERTFLKAIEGS
CHVPVGGYATVNGDDVTLTGLIASVDGKEVLRVTKTSTDGVALGQAVAEELLGRGGREIL
ASVNE
>B6JKG8|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain P12)|Swiss-Prot
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGTIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFATLQKLNDEKSAFCCRLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKRGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>B9E743|hydroxymethylbilane synthase|EC 2.5.1.61|Macrococcus caseolyticus (strain JCSC5402)|Swiss-Prot
MRKIIVGSRRSKLALTQSQQFIDQLKRKHPNLEIEIKEIVTKGDQIVNVQLSKVGGKGLF
VKEIEQALYDGTIDFAIHSLKDVPSVLPEGLTLGCIPVREDARDAYIAKHHIPLHELKPG
SIVGTSSLRRGAQLLDQYPHLEIKWIRGNIDTRLAKLRDEDYDAIILAAAGLNRMGWDKS
IVTEYLNPELMLPAIGQGALGIECRSDDAEVLALLKSVHDEETELCTEAERTFLRLMDGS
CQVPIAGHATMVGESIEFTGLIMSPDGKEKYKVTHSGGNPIEIGTQVAKAMEQNGAKAII
ETLNQDI
>B2A1G7|hydroxymethylbilane synthase|EC 2.5.1.61|Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF)|Swiss-Prot
MKLRIGTRRSQLALDQTNWVVEQLKTHYPDIEIEIKKIETKGDQLLNVSLSKVGGKGLFL
KEIQNALLQGEIDLAVHSMKDIPTETTEDLEICAITKRVDPLDALISNNDITIDELPENA
KIGTSSLRRGSQLKAYRNDLQIIPIRGNINTRMNKLQELPELDAVVLAKAGLVRSGMTDS
ISQNISPEIIVPCPGQGALGLEIRHDNENLKEKLAVLDDSESRKAIGAERAFLNRLGGSC
HVPVGAYAEIISNELHLTGVVASEDGQDVIKRSVQTHLSDNNKIPSTLGNDLAEELIELG
ANKILSELKEG
>Q6AB05|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes (strain KPA171202 / DSM 16379)|Swiss-Prot
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>Q500N6|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. syringae (strain B728a)|Swiss-Prot
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDQLP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGSVLLHADARAPQTSAQALGVQVAEALLEQGAA
DILKAVYGEANNE
>B5FN93|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella dublin (strain CT_02021853)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>O34090|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain NCTC 8325)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q31PM2|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus elongatus (strain PCC 7942)|Swiss-Prot
MVSSPARPIRIGSRKSQLALVQTHWVQGELQRLYPDRQFDVQTMSTQGDIILDVALAKIG
DKGLFTKELEVAMLAGEVDFAVHSLKDLPTRLPEGLILGCVTEREDPADALVVHDRFKDH
QLETLPEGTVIGTSSLRRLAQLRHHYPHLQFKDVRGNLNTRLAKLDAGEYDALILAAAGL
QRLSMADRIHQLIPAAVSLHAVGQGALGIECRAEDPEILELLKALEHEPTSQRCLAERAF
LRELEGGCQVPIGVNTAIADGTLTLTGMVASLDGQRLLRDQVSGPTSDPEALGLALAAQL
KAQGAKEILDEIFATVRPEA
>C0R2M3|hydroxymethylbilane synthase|EC 2.5.1.61|Wolbachia sp. subsp. Drosophila simulans (strain wRi)|Swiss-Prot
MLVKIGTRGSKLAVVQALEAKQKLLDSFPNLSIEIVKIKTSGDKYANANLAEIGGKGLFI
KEIEAELLENNIDMAVHSLKDVPAFFSWGLTIPCVLERLSPCDAFISHKHNSLESLPQQA
TIATSAIRRKVQLLNFRPDLNIVPLRGNVTTRLQNQSFDGIILAEAGLIRLEKHHLITEV
LPPKVMLSAVGQGAICIQCRRNDVKIIDLLEKINNNMSFIGVKSERSFMKTVNGSCFTPL
AALAEYVSENMLYLRCMLADGKNIYFTERTSFIEDAEKMGMDAGLELKSKCL
>B6EPK1|hydroxymethylbilane synthase|EC 2.5.1.61|Aliivibrio salmonicida (strain LFI1238)|Swiss-Prot
MSQQLPVRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDIILDTPLAKIGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVEFPEGLGLVTICERGDPRDAFVSNTYNNIDEL
PQGATVGTCSLRRQCQLKEYRPDLIIKELRGNVGTRLQKLDDGNYDAIILACAGLIRLGL
EDRIKSSIEPEQSLPAVGQGAVGIETRLNDDRIRALLAPLNHPETAHRVLCERAMNNRLE
GGCQVPIGSYSLIDGDQIWLRALVGEPDGSIMVRGETTGPVSDAEELGTKLAEQLLNDGA
KDILDRLYADA
>Q1LU25|hydroxymethylbilane synthase|EC 2.5.1.61|Baumannia cicadellinicola subsp. Homalodisca coagulata|Swiss-Prot
MLNNILKIATRQSPLAIWQANYVRNQLLSFYPTLLIELVPIVTSGDLILDKPLMKAGGKR
LFIKELEQAMLERRADIAVHSMKDITISFPEGIGLAVLCAREDPRDAFISTHYASIDLLP
TGAVVGTSSMRRQCQLRERRPDLVMRDLRGNIGTRLEKLDKGEYDALILAAAGLKRLDLA
HRIRMIIDPTELLPAVGQGVIGIEYRLEDTHILSILAPLHHSATALRVSAERAMNAKLAG
GCQVPIGSYAEIEGDQIWLRALVGSPDGSLIIRSEGRAPLSQAEILGQSIANDLLYRGAE
SILCRAFQVDS
>A3N700|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei (strain 668)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMVLPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>Q9Z9C9|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia pneumoniae|Swiss-Prot
MLSVCYSDPCLSDFCQGKRPLRIASRNSNLAKAQVHECISLLRSWYPKLWFQLSTTETTG
DREKKIPLHLVENSYFFTDGVDALVHKGVCDLAIHSAKDLPETPSLPVVAITRCLHPADL
LVYADHYVHEPLPLSPRLGSSSLRRSAVLKQLFPQGQILDIRGTIEERLDQLHRGHYDAI
VLAKAASLRLHLHHAYSIELPPPYHALQGSLAITAKDHAGKWKQLFTPIHCHSS
>Q8NT90|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)|Swiss-Prot
MTLKIGTRGSKLATTQAGTIRDQLKHYGRDAELHIVTTPGDVNMSPVERIGVGVFTQALR
DVLHSGECDVAVHSMKDLPTATDPRFHLVVPTRADSREALIARDGLTLAELPEGAKVGTS
APRRISQLKAIRPDLEILPLRGNIDTRMGKVTSGELDAVMLAYAGLTRVGMQDRATEVFD
ADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAERTVLNRLEAGCTAPVAA
HATLDGYSGDTMTLTAGVYALDGSDQLVFSAEGDGARPEELGELVAQQLIDAGAANLLGD
RS
>B7M603|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O8 (strain IAI1)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B3E2H7|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)|Swiss-Prot
MAPKRLRIGTRASQLALWQANWTKSELEARYPGIQVELVKIKTMGDKILDVPLAQVGGKG
LFVKEIEEAMLRGEIDLAVHSMKDVPTEFPEGLGLVVTTKREDPRDAFISDKVTFSELRQ
GARIGTSALRRQAQLLKARPDLEMVIIRGNVETRIRKLKEDNLDAVILAAAGLNRLGFTD
VVTELLDTDFSIPAIGQGALGLECRLDDNATIEALAFLNHADTAAAVAAERALLKRCEGG
CQVPIAAHGTVSGDTLTLVGFIASVDGKQTVRDRISGSTADAVKLGTELADRLLAAGGKA
ILEDVYQREIAH
>Q6CT60|hydroxymethylbilane synthase|EC 2.5.1.61|Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)|Swiss-Prot
MESKETVRIGGRRSKLAVVQSEQVKVMIESKFSHIECPLLSVHTLGDQVQSKPLYSFGGK
AVWTKELEDLLYKDDESRIDLIVHSLKDMPTLLPDGFELGGITKRVDPTDALVMPIGSPY
SSLSELPDGSVVGTSSVRRSAQLKRKFPNLKFESIRGNIQTRLAKLDDPETPYKCIVLAS
AGLMRSGLDSRITQRFNADTMCYAVGQGALGIEIRKDDEKMKKILKEICDPSTTICCLAE
RSLLRTLEGGCSVPIGVVSNYDESTKVLTLKGIVINVEGTEWVEIEHKVTISNEREDSIN
CGKELAAKLTQNGAKEILDSINLDKIT
>C5CB88|hydroxymethylbilane synthase|EC 2.5.1.61|Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230)|Swiss-Prot
MSPLRIGTRGSALATTQTSHVAEALTARSGLAHELVVIRTEGDVTTGSLASLGGTGVFAS
ALRAAVLDGVVDAAVHSLKDLPAAQPETLEIAAVPARADLRDALCARDGLTLATLPEGAR
VGTGSPRRVAQLKALRPDLELVDIRGNVQTRLARVPGLEQHDDHAPAAVGSPRGDLDAVI
LACAGLDRLGLDHVITERIDPEVMVPAPGQGALAMEIRAEDESFLGRALLDPEAPVGRLH
AALELVDDRDTHVAVTAERALLRRLEAGCAAPIGAVARVGDGEAGAPRIEMTAMVAALDG
SRVLRRTSSVQLDPVPADVVGDPAAADEWLEDTLFVAAEALGVHVAEQFVAEGADLLPGT
VRGVDRGDGAPRPDDPA
>A5CDH4|hydroxymethylbilane synthase|EC 2.5.1.61|Orientia tsutsugamushi (strain Boryong)|Swiss-Prot
MIIRVGSRASRLALIQAQAVVQKINDLLGLNAIIIPIKTTGDLIQNKNLYDIGGKGLFLK
EIEYALLNNTIDIAVHSLKDVPAYLPDGLQLAAVLERGDVGDMLVSKIANKITDLPLGAI
VGTSSVRRRIQLLMLRPDLNIVLFRGNVDTRWNKIINNEVDATVLAAAGLQRLNYDTSRF
CNIIPQSEMLPAIGQGAIAIEARKDDKLIMPLCAKINHQLTWQLIQVERGYLKTLNADCN
VPIGGIASYIGNNSFEAKFMLGDYNMRYFFYSEVRGKLQHGYDIGVEAAKNFQKRLFI
>A2BPX7|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain AS9601)|Swiss-Prot
MTNFKLKIASRRSKLAMVQTLWVKDQLEKNIPNLEVSIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGHADIAVHSLKDLPTNLPNGLKLGCITKREDPADALVVNKKNDCYKLE
NLPEGSIVGTSSLRRLAQLRNKYPHLVFKDIRGNVITRIEKLDAGEFDCIILAAAGLKRL
GFESRIHQIIPSEVSLHAVGQGALGIECKSDDKKVLEIISILEDKPTCQRCLAERAFLRE
LEGGCQVPIGVNSKIQNEQLCLTGMVASLDGERLIKDQYIGDINDPEEVGKELAKKLKQQ
GAEEILSEIFKKFREK
>Q088L3|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella frigidimarina (strain NCIMB 400)|Swiss-Prot
MSENIIRIATRKSPLAMWQAEFVKAELERIHPGLTVELLPMSTKGDVILDTPLAKIGGKG
LFVKELEVAMLENRADIAVHSMKDLPVEFPEGLGLQVICEREDPRDAFVSNNYKSISELP
QGAVVGTSSLRRQCQIRAARPDLVIKDLRGNVGTRLAKLDSGDYDAIILAAAGLIRLKLN
ERIANFISAEESLPANGQGAVGIECRTDDARVKALLAPLEHLETRYRVLAERAMNTRLEG
GCQVPIGAFAEINGDNLTLRGLVGNPDGSQIIIGTVSGSKTDAVALGESLAEDLLSRGAK
TILDAVYAS
>Q8CNY8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis (strain ATCC 12228)|Swiss-Prot
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>Q72H57|hydroxymethylbilane synthase|EC 2.5.1.61|Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)|Swiss-Prot
MRVVVVGTRGSALALAQTRFVVERLKETWPETEFKIRTIKTRGDQGASPREEAIFVKEIQ
EALLSREIDIAVHSLKDLPTESPRGLKIASVPRRQDPRDVFLGKAAKRLKDLPPGAVVGT
SSVRRKAQILALRPDLVVRDLRGNVDTRLAALGNGEYDGIVLAAAGLIRLDLRNRIDEFL
DPGEVLPAPGQGALALEVREGDDLAEELCYALHHPPSYHRVRAERAFLRGLGAGCLAPVG
ALAHVEEDGTLRLEGVLLTPDGKSFIRAEIEGDVSEAEELGLDLARDVLEQGGREILAQI
R
>Q6C097|hydroxymethylbilane synthase|EC 2.5.1.61|Yarrowia lipolytica (strain CLIB 122 / E 150)|Swiss-Prot
MSVEERPVIFDDQSELPKVFVGGRKSKLALVQTQHVAAMLKKVHPDYSFPVLGLTTLGDQ
VQSKPLYSFDGKALWTKELETLLLEKVPGFDQQDIIVHSLKDMPTVLPDGCELGAILTRE
DPRDALVMAAGSPYKTLADLPAGSVVGTSSIRRSAQLKKSYPGLVYESVRGNVGTRLSKL
DDPETPYKCLILAAAGLKRLDLGDRITGYLQKPDMLHAVGQGALGLEIRQGDEKTKKILE
AIYDKESTLCCLAERAVMRTLEGGCSVPIGVETKYENGKLTLDAIVVSVEGTEFVECTQV
RAVEENWEAEQLGKDVAEQLVKDGAKKILDAIHLENIK
>B7JQ57|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain AH820)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>C0RFD1|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella melitensis biotype 2 (strain ATCC 23457)|Swiss-Prot
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDVLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>A7H4J7|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)|Swiss-Prot
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSTDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNEFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESIKDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGEGLAKEFITKGAKELL
KKAESII
>B1IHD1|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain Okra / Type B1)|Swiss-Prot
MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
>C6BYB7|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763)|Swiss-Prot
MRKITIATRGSKLALWQANHISDLLREEYPGIEVQLLKIKTKGDKILDVPLAKVGGKGLF
VKEIEEALLDGRADLAVHSMKDVPTELPEGLEVGIIPPREAETDTLLSVKYDSLKDLPAG
AVVGTSSLRRQSQVLALRDDLKIESLRGNLDTRVGKLLNGEFDAIVVATAGLNRLKLSAP
KSEILGPPTFLPAVAQGALGIEYRIEDTEIQDILAFLHDEMTARQVKAERGFLTGLDGGC
QVPIAAWSQLESDQVKLTGFVADIDGSSPIRMEKTGPAEDAWDIGLALAEEVLAAGAKEI
LDRVYDKC
>B7LU53|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDALMAKHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNKYASLDELP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRDALPPEVSLPAVGQGAVGIECRLDDTRTRELLAALNHPETALRVTAERAMNTRLEG
GCQVPIGSYAELIGGEIWLRALVGAPDGSQMIRGERRGSPQDAEKMGISLAEELLNNGAR
AILADVYNGDAPV
>Q9HMY5|hydroxymethylbilane synthase|EC 2.5.1.61|Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)|Swiss-Prot
MSSQQIRLATRGSDLALRQAGEVVDTLEDRRHDVELVEVETEGDRVTDALISDLGKTGAF
VRALDQEVMEGTVDAAVHSMKDVPTEVPEDLVVAAVPHRENPADVLVTPDGTDLEDLPAG
SVVGTASLRRGAQVQAHRPGLDVEPIRGNVGTRVEKLLAPALHREHERRTEAEKEAQSRD
AREQRRGDYTADIEAGVENLDTEDGEEGAADDGDDTASSSEFEQSVTEWFDSLTPLQQSA
MERDPDTEYDALVMARVGLERTGLLHHVGIEELSTGTHVPATGQGALCVTARRDSDVVDT
LRDALEHVRTRVEVTAERVVLEELGGGCIAPIGVHALVQGDTIRTAVQVFSQDGSEQVGE
TRELDAEQYATDARELAADLRDRGAADLIEDARTEA
>B8DHJ2|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 4a (strain HCC23)|Swiss-Prot
MKRKIIVGSRRSKLALTQSNWVINKLKENYPAFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDKTIDFAVHSMKDVPSSLKEGLVIGAIPKRESPLDCFVFNQVNALDELPH
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATKANEAVHFKGLVGNADGSIILEAEQTGANPSEIGNKVAEDLLSKGAD
TIIQELRNI
>P64336|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis|Swiss-Prot
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>P64336|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis|Swiss-Prot
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>B4RC21|hydroxymethylbilane synthase|EC 2.5.1.61|Phenylobacterium zucineum (strain HLK1)|Swiss-Prot
MPTQPVVRIGARGSKLSLTQSGIVQRRIAAALGVDPDNAAEVERVAPLIPITTTGDRVQD
RRLLEIGGKGLFTKEIEEALMDGRIDCAVHSMKDMPAELPEGLCIAAIPEREDPRDAFIS
RGPERLEDLTEGAILGTASLRRQAQCLHRRPDLEAKLLRGNVETRLGKLEAGEYDAILLA
YSGLRRLGLGHLPKSLIDPKEAPPAPGQGALAVETRAADRDLPWAQALRCRPTTLAVAAE
RGALIALEGSCRTPIGAHAWLEGGTCKLIVEALSPDGKLRFRHSGEAELSQMADPEASAR
DLGLSLGLAVKEEAGDAIVL
>B0KH05|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas putida (strain GB-1)|Swiss-Prot
MSTREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDAPLAKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTFDSLEALP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSTISVDDSLPAGGQGAVGIECRSADVEIHALLAPLHHADTADRVVAERALNKHLNG
GCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRTAAETLGVQVAEDLLSQGAE
AILKEVYGEAGHP
>A5UU37|hydroxymethylbilane synthase|EC 2.5.1.61|Roseiflexus sp. (strain RS-1)|Swiss-Prot
MKQTLIIGTRASKLALVQTYMVRDALQSAHPGLTVAVEHITTRGDIILDRPLNAIGDKGL
FVVEIEEAMRAGRIDLAVHSAKDLPSVLPPDMTLAACPRRADPRDALVAQPGMTLAALPS
GARVGTSSLRRACQLRALRPDLTLVDLRGNVDTRLRKLREGQYDAIVLAAAGLKRLGLDG
AISELIEPDVLIPAVGQGVIGVEARADDEEVLRLLAPLDDQAARIAITAERAFLARIGGG
CQVPVGALAHLEGDELLLRGMIGARDGRMVRGMQRGSASDPVGLGCALADELLDQGGRAL
LAG
>Q1GP41|hydroxymethylbilane synthase|EC 2.5.1.61|Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)|Swiss-Prot
MNELATPDNPLRIGTRASPLAMAQAHMAAAALIAAHGLAMAALEIVPMTATGDRIQDRAL
AEVGGKALWTRELDAALDAGTIDVAVHSLKDVETLRDARFFLGAMLERADPRDRLVVREG
IAAQKISELPHGARLGTSSPRRAAQVRRLRPDLDTVLLRGNVATRLAKLAAGEADATLLA
AAGLERLGMHDIGAVQGTELLLPAASQGAIGIECRADDAATIALLAAIDHAPTHRAVAAE
RALLAVLGGDCRSPVAAYAEWQADGVLRLDAEIFSEDGADHVAGHVIVTDAGVVAALGHR
LLAEAPPSIRRLFAT
>A6Q7Y4|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurovum sp. (strain NBC37-1)|Swiss-Prot
MEKLVIATRASNLALWQAYHIKERIETAFPEVRVELNEITSKGDKILDKPLALVGGKGHF
TKELEDEMIAGNAHLAVHSLKDVPTYIPEGLELCAITERQDQSDVFLSHTYKSLSELPEG
AVVGTTSLRRRMQLLEKRPDLKVKDLRGNVNTRLRKLKEGQYDAIILAYIGLYRLDLLKD
IPYVEKLDFFIPPMGQAALGIEIVANNDRIREIAMTLNHEPTFICTKVERDFISVIGAGC
SAPVAVNATMDKKEDDKVPTISVRAMIGYPDGTHILHKSLTVPLNEADILGDELAQAMIE
EGALDILEQAEIIAFKDEMPERL
>B7VMD9|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio splendidus (strain LGP32)|Swiss-Prot
MTNSAPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQLLEYRPDLIIKELRGNVGTRLGKLDDGQYDAIVLAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYSLLDGDNIWLRALVGEPDGSKMVRGEISGLRKDAEALGVTLANQLLDDGA
REILTKLYADQE
>Q43316|hydroxymethylbilane synthase|EC 2.5.1.61|Arabidopsis thaliana|Swiss-Prot
MDIASSSLSQAHKVVLTRQPSSRVNTCSLGSVSAIGFSLPQISSPALGKCRRKQSSSGFV
KACVAVEQKTRTAIIRIGTRGSPLALAQAYETREKLKKKHPELVEDGAIHIEIIKTTGDK
ILSQPLADIGGKGLFTKEIDEALINGHIDIAVHSMKDVPTYLPEKTILPCNLPREDVRDA
FICLTAATLAELPAGSVVGTASLRRKSQILHKYPALHVEENFRGNVQTRLSKLQGGKVQA
TLLALAGLKRLSMTENVASILSLDEMLPAVAQGAIGIACRTDDDKMATYLASLNHEETRL
AISCERAFLETLDGSCRTPIAGYASKDEEGNCIFRGLVASPDGTKVLETSRKGPYVYEDM
VKMGKDAGQELLSRAGPGFFGN
>Q7W785|hydroxymethylbilane synthase|EC 2.5.1.61|Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)|Swiss-Prot
MAAVERLTIATRASRLALWQAEHVRDLLRARYPACSVELLTLTTRGDQILDRTLSKVGGK
GLFVKELETALLDGRADLAVHSLKDVPVDLHAPFELSCVLERADPRDAFVSNDYGSLADL
PPGAAVGTSSLRRESQIRARYPHLVVKPLRGNLDTRLGKLDNGDYAAIVLAAAGLERLGL
AARIRALLEPADSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAERAVSRMLG
GSCQVPLAAYARIDGDELALRALVAAPDGRRIVRAERRGPRDQAQAIGESAARDLLADGA
DAILAELLPTSPAP
>Q2T071|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMELPAGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARYPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVEDSLPAAGQGALGIEIAAGRADVAAWLAPLHDHATALAVEAER
AVSRALGGSCEVPLAAHAVWRGDELHLTGSVSTTDGARVLAARAQSRAATAADALALGRA
VSDELERQGARAIVDALVAASAQAQKGGA
>Q7P207|hydroxymethylbilane synthase|EC 2.5.1.61|Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)|Swiss-Prot
MDKIVIASRESRLAMWQAEHIQARLQALYPHLTVEILGMTTQGDQILDKTLSKIGGKGLF
VKELEQALMDGRADLAVHSLKDVPMTLPDGFALAAVCEREDPRDAFVSNRYQHLSELPAG
SVVGTSSLRREAQLRARFPQLAVKPLRGNVQTRLKKLDDGEFDAIILAAAGLKRLGLAER
IQGELAPSESLPAAGQGALGIEIRADRADLSALLAPLNHPDTRACTAAERALAKELGGSC
QVPLGAFATLADGTLTLGGLVAHPDGSVVLTASASGPADYADALGRAVAKKLIDAGARPL
IAAVLAEPR
>A9N910|hydroxymethylbilane synthase|EC 2.5.1.61|Coxiella burnetii (strain RSA 331 / Henzerling II)|Swiss-Prot
MIKKRSILIVTRKSPLALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGK
DLFVKDLQKALLNRDADIAVHSIKDMSACDGPELMVGAFIRREDPRDVLIVKGELSTLPP
HAVIGTSSPRRQCQLKKFQPGCKIKEIRGNVGTRLAKLDAGHYEAIVLAAAGLKRLGLEN
RIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAERAVNEKLGGD
CFTPIAAHAIIKNDQFSLFAMLGKIDGRVIIRATEIGNSEEAKRIGFKVASQLLEQGGDS
LLRELKQ
>P06983|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain K12)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C6DYY8|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter sp. (strain M21)|Swiss-Prot
MALKELRIGTRASQLALWQANWVKSELEKRYPDMTVTLTKIKTIGDKILDVPLAQVGGKG
LFVKEIEEAMLRGEIDIAVHSMKDVPTEFPEGLGLYCITEREDPRDAVISNNVKFADLPQ
GARIGTSALRRQAQLLKVRPDLEMVIIRGNVQTRMDKLKTEGLDAVILAAAGLNRLGFAD
QITELLPTDLSLPAIGQGALGIECNLSNQDVKDAISFFNHPDTSRAVRAERALLWRCEGG
CQVPIAAFGEVTGDELKLTGFIASVDGKVSVKGVVTGPADDCEKLGVKLAEQLLSEGGHA
ILAEVYQREVSREKEIPV
>C1D679|hydroxymethylbilane synthase|EC 2.5.1.61|Laribacter hongkongensis (strain HLHK9)|Swiss-Prot
MKQVVIASRESPLAMWQAEHIRARLQALYPGLEVSILGITTQGDRILDKTLNKIGGKGLF
VKELELAMQEGQADLAVHSIKDVPMDLPEGFALAAICEREDPRDAFVSSRYASLSELPAG
AVVGTASLRRESQIRARYPHLLVKPLRGNLQTRLRKLDEGQYDAIILAASGLKRMGLAER
IRMELSTADSLPAVGQGALGIEIRADRTDLMALLAPLNHPATYACVTAERAMGRALGASC
QIPVGGYAEQHEHMLVMRGFVATPDGTTLLHAEATAPAEYADALGRTIAKKLLDQGADDV
IDAVKAAG
>B1MHI5|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)|Swiss-Prot
MIRIGTRGSLLATTQAGGIRDALRAKGHEAELVIVTTAGDQSAAPVEQIGVGVFTAALRE
AIADDVVDVAVHSYKDLPTAADPRFVIPAIPPREDYRDALVARDGLVLGELPAGSVIGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLSRVSNGDLDGVVVARAGLARIGRLDHITETLE
PVQVLPAPAQGALAVECRSEATDLVAVLAELDHADTRAAVTAERALLAELEAGCTAPVGA
IAEVVESIDEEGRVFDELSLRGCAAALDGSDVIRASGIGTPDRAAELGLAVARELLDLGA
RALIGR
>A1B853|hydroxymethylbilane synthase|EC 2.5.1.61|Paracoccus denitrificans (strain Pd 1222)|Swiss-Prot
MTQMPDPQNPIRIGTRGSALALAQAHETRDRLMAAHGLAADAFRIVVIKTTGDRVLDRPL
KEIGGKGLFTREIEDALLAHEIDIAVHSMKDMPTIQPEGLVIDCYLPREDVRDAFVSAQF
AAISELPQGAVVGSSSLRRRAQLAARRPDLKLVEFRGNVQTRLKKLEDGVAVATFLAMAG
LTRLGMLHVARGAVEPDEMLPAVAQGCIGVERRADDARTASLLAAISDRDSALRVTAERA
FLARLDGSCQTPIAGLAELQGDRLRLRGEILRPDGSEVIAAERVGPAADGAAMGTDLAEE
LRGRAPADFFDWS
>A6VE37|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa (strain PA7)|Swiss-Prot
MSSREIRIATRQSALALWQAEYVKARLEQAHPDLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLDQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSISVDDSLPAGGQGAVGIECRTADADLHALLAPLHHADTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGSQLLRAEGRAPLAQAEALGVQVADDLLAQGAE
AILAAVYGEAGHP
>Q92HR5|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia conorii (strain ATCC VR-613 / Malish 7)|Swiss-Prot
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRMPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVLEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKVSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>A4YBG2|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAILEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNIYKTISELP
LGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
GRIASFISAEQSLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEG
GCQVPIGAFAEINGDEMTLRGLVGNPDGSEIIEGIITGPKTEATQLGVALAEELLSKGAK
SILDAVYAKA
>B2FI06|hydroxymethylbilane synthase|EC 2.5.1.61|Stenotrophomonas maltophilia (strain K279a)|Swiss-Prot
METVRIATRKSPLALWQSEHVADRLRQAHPGLHVELVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDPPFALPAMLTRHDPADGFVSNLYASLDALPIG
ARVGTSSLRRQAQLRALRPDLELLDLRGNVNTRLAKLDNGGYDAIVLAVAGLERLGLGER
IVARLQPPQWLPAPAQGAVAVECDGGNARLMALFAPLDDAATRACVEAERAMNRALHGSC
HVPVAAIAQWQGDDLHLQGLVGSASDGRAVRAEAVGPANDPEGLGQRVAKLLLDDGAGEL
LNV
>Q3SFT5|hydroxymethylbilane synthase|EC 2.5.1.61|Thiobacillus denitrificans (strain ATCC 25259)|Swiss-Prot
MHTLTIASRESALAMWQAEHIRDRLRELHPECKVNILGMTTRGDQILDVTLSKIGGKGLF
VKELEVALAAGEADLAVHSMKDVPMELPPGFELAVIGEREDPRDAFVSNRYARLSDLPPG
SVVGTSSLRREAQLRARYPHLTVKPLRGNVGTRLKKLDEGQFDAILLAAAGLKRLGLGAR
IKSLLSVEESIPAAGQGALGIEIRSGNTAVAAMLAPLNDPVTAACVRAERQVSRVLGGSC
QVPLGAHASYKDGRLLLEGFVAKPDGSRFLVDRAEGDASDPEAVGQALADKLLAQGARAV
LDALPA
>A7FD67|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>Q75DY0|hydroxymethylbilane synthase|EC 2.5.1.61|Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)|Swiss-Prot
MGEETLRIAGRRSKLAVIQSESVKEIVQREFPNYTCTVLAKQTLGDQVQSKPLYAFGGKA
LWTKELEDLLYEEDLDQRIDMIVHSLKDMPTQLPEGFELGAITKRVDPSDCLVMAAGSPY
KTLGDLPNGSVVGTSSIRRSAQLRRRYPHLVFASVRGNIQTRLKKLDDPENECKCIILAT
AGLVRLGLESRITQRFDSTIMLHAVGQGALGIETRTGDERLQAILAKVADRNSTICCLAE
RSLMRTLEGGCSVPIGVYSTFDEETSMLTLDGLVVSVDGADAAEATVSYKIKSDKEDAIA
CGQLLAAKLLEAGAKKILDAIHLPEA
>Q2KIN5|hydroxymethylbilane synthase|EC 2.5.1.61|Bos taurus|Swiss-Prot
MSGNGNAAAIAEEDTPKMRVIRVGTRKSQLARIQTDSVVATLKALYPGLQFEIIAMSTTG
DKILDTALSKIGEKSLFTKELEHALERNEVDLVVHSLKDLPTVLPPGFTIGAVCKRESPY
DAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFKSIRGNLNTRLRKLDEL
QEFSAIILATAGLQRMGWQNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHD
PETLLRCIAERSFLRHLEGGCSVPVAVHTAIKDGQLYLTGGVWSLNGAETMQDTMQTTIH
VPVQHEDGPEDDPQLVGITARNIPRQPQLAAENLGISLATLLLNKGAKNILDVARQLNEA
H
>A4XK06|hydroxymethylbilane synthase|EC 2.5.1.61|Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903)|Swiss-Prot
MKKLRIGARDSKLSRIQVDIVARKIKQTLGIECEFVPIKTKGDIDKTKSLKDFKSPGVFV
KEIELALLSREIDLAVHSLKDLPCEMDSNFEIVAVVEREDPRDVLVSKDGVGFYQLKPNA
KIGTSSLRREVHLKNLRQDIQVVNIRGNIETRLSKIESEGLDGVVLAYAALKRLNLDSHV
SYIFDVNEITPCPGQGAICIECLKDSPYKNILSKINDADAYIQTQFERLVLKFLGGGCHS
SIGVFCKTDQDKIYAFASILSGDKLIKASIEGDKDDFLSLANKLSNMLKS
>C3L2Z3|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain 657 / Type Ba4)|Swiss-Prot
MNFIIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLREGAK
IGTSSRRRAAQLKLLRSDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
>Q11XT5|hydroxymethylbilane synthase|EC 2.5.1.61|Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)|Swiss-Prot
MNKTVRIGTRGSKLALWQAEHVAACLQTKGLEPQIVIIDTTGDKILDQSLSKIGSKGLFT
EELEEQLHAGTIDIAVHSAKDLQTHLKGGMYILAITERELVNDVLVSHKPIDTLKNNPDL
IIGTSSTRRRALLRKFYPQAKMVDMRGNLQTRIRKMEEGACDAMLLAYAGMHRMGYDSLI
KEKLSLEEFIPAAGQGTLAIEAASTLDKEKAAVIRAVLNDAATETAVSAERAFLRTLEGG
CSIPVFALAVERDTDYLLTGGIVSLDGTKYLRKEIRFTAADAEQRGVELATVLLKDGADE
ILAEIKKGLSKS
>Q3YSA8|hydroxymethylbilane synthase|EC 2.5.1.61|Ehrlichia canis (strain Jake)|Swiss-Prot
MNIRIGTRGSVLALAQTLEVTNLLNRYFPEINIQVVKIKTSGDINNKVPINTIGGKGLFI
KEIEEALLIGKVDLAVHSVKDIPAFYCDGLIIPCVLKRSSPYDVFVSSKYQSIKSLPINA
TVGTSSIRRKVQLNYLRPDLQVIPVRGNIDTRILKSDIGEFDGIVLAEAGLIRINKCNVI
KEVLDSKIMLSAVGQGAICVQCRADDYNIINKIKVLNCHKSYVCVIAERSFLKTINGSCD
TPLAALAQYVDSDTIYMSCMLSNEKEMVFSDCYFKECNAEESGIDMGKKLINELYGSC
>A5GCW2|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter uraniireducens (strain Rf4)|Swiss-Prot
MALKTLRIGTRASQLALWQANWVKSELEKRYPGLEVSLLKIKTIGDKILDVPLAQVGGKG
LFVKEIEEAMLRGDIDIAVHSMKDVPTEFPEGLGLHCITEREDPRDAVISRGIKFADLPK
GAKIGTSALRRQAQLLKIRPDMEMVIIRGNVETRINKLEAENLDAVILAAAGLKRLGFTD
KVAEYLPTDLSIPAIGQGALGIECRLDNEEVKSAIDFFNHPATAYAVRAERALLWRCEGG
CQVPIAAFGEVEGDQLKLTGFIASVDGKTSVKGSVSGPAEECEKLGITLAEQLLKDGGHE
ILAEVYQREVSREKEIPV
>Q5ZRY6|hydroxymethylbilane synthase|EC 2.5.1.61|Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)|Swiss-Prot
MSAKIIRIATRQSPLALWQANHVREMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKG
LFVKELEEALLDKRADLAVHSTKDMPAQLPDGLLLTAICKRDNPFDALISPQFKSLAALP
KNAIIGTSSLRRQSQLLAYNPNLQIKTLRGNIHTRLSKLESGEYQAIILAAAGLERMGLA
HHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELVHGLNDPISALCVHTERRVNAKLGG
NCHIPFAVYCTITEEKLLLLRAKVLNMDGSQMIDDEQQGKIAEAEVIADRCTESLMTKGA
MSLLSTIPS
>C1AKJ0|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)|Swiss-Prot
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>C6DHC2|hydroxymethylbilane synthase|EC 2.5.1.61|Pectobacterium carotovorum subsp. carotovorum (strain PC1)|Swiss-Prot
MLANIIRIATRQSPLALWQARYVQQCLNHLYPDLHVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPVEFPDGLGLTTICERDDPRDAFVSNRYDSLEQLP
EGSCVGTSSLRRQCQLRARRPDLVIRDLRGNVGTRLAKLDNGEYDAIILAVAGLKRLGLE
ERIRCALSPEESLPAVGQGAIGIECRLNDDRIRQLLAPLNHPATAARVQAERAMNVRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIVGERRGNVSDAEQIGIALAEELLAKGAS
AILQAVYHESSSS
>Q60169|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)|Swiss-Prot
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAE
AILEAVYGEAGHP
>Q9ZD77|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia prowazekii (strain Madrid E)|Swiss-Prot
MINSIRIGTRNSTLALIQTNLVIEQIKQIFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGKIPVELVIAAVLEREDPRDVLVCLNYQSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDAIILSYAGLKRLNVFN
QKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPERAFLEYLDA
NCSTPIAAYAQYLDAYNIQIDFMLGNLDCTKIIFQTEITNIKTSKICGIKAAKMMLAQQ
>Q0HN99|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella sp. (strain MR-4)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERVHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELP
LGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEG
GCQVPIGAFAEIHGDEMTLRGLVGNPDGSEIIEGVITGPKTEATKLGVALAEELLSKGAK
SILDAVYAKA
>C3MZR8|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain M.16.27)|Swiss-Prot
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIIDIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLERDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNENIIP
>A5CW34|hydroxymethylbilane synthase|EC 2.5.1.61|Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)|Swiss-Prot
MNKTLKIATRQSPLALWQAQHVKSRLEKIYPNLTVILVKITTKGDQILNSSLSKIGGKGL
FIKELEISIMKGMSDIAVHSMKDVPYEIPQEFELGAILKCENPFDAFVSNHFSSIDDLPK
NAKVGTCSMRRILQLKVIRPDLQIIDLRGNVNTRLKKLDDGEFDAIILACAGLIRLGFGN
RIKQQIPENQNLPAVGQGAIGIEIRENDKEILDLIKPLIDIETSYRIIAERAMNTQLEGG
CSVPVAGFATINNKQITLTGLVGNIDTGVILKEKIFGHVSQAEILGIELANKLILLGAKD
ILKD
>P46355|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>B7IIX5|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain G9842)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDDE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDAITERTVAAERVFLHKLEGG
CQVPIAGYATLKENDTIELTALVGSMDGSVLLKETVVGTNPEEVGLEAAGRLIKQGAKEL
ILAANKEQQ
>A5VSL5|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)|Swiss-Prot
MKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPLSEVGGKGLFT
EEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSARRFMDLPQGA
TVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAGLRRLGLADVI
TDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERAFLGALDGSCR
TPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANRVRAMAGPHFF
DGWQ
>A1VYQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)|Swiss-Prot
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>B1KY15|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain Loch Maree / Type A3)|Swiss-Prot
MNFIIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLREGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIVKKEITGTKDQYEKLGIALAEHILKD
>Q30Y29|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio desulfuricans (strain G20)|Swiss-Prot
MKKIVIATRGSKLALWQAEHIKERIMQQYPDSFEVELLVLKTKGDIILDVPLAKVGGKGL
FVKEIEEALLDGRADIAVHSMKDVPMELPQGLTLGAIPEREVPTDSLLSARYDGLDALPQ
GAVVGTSSLRRQSQILAMRPDLEVKWLRGNVQTRIRKLMDGEYDAIIMATSGLKRLGETA
PFHSELGPPLFMPAVGQGALGLEYRSDRQDLAEMLAFLDHRPSRICVEAERGFLFGLQGG
CQVPIAGYAVMTGDNSFELTGLVAELDGTAVIRRTAAGTEADARDTGLTLAAQVKAAGAD
AILQRVYENGHASPQA
>P13446|hydroxymethylbilane synthase|EC 2.5.1.61|Euglena gracilis|Swiss-Prot
MYCGRYETIGETRGNSLNVFIGAAAGFVAAVALINSGLATSFYSTPVRAVPQVIVPSSLA
ASSQLPVVPKETNIQVNSAQILYPDSTVKGQERTITILGVCSFLSASLFYIWKQFGMKAR
TTKPADLQEVSGGRIWSLASTTGSNIGAGKTVRVATRKSPLAMWQAEFIQSELERLWPGI
TVELQPMSTRGDKILDSPLAKVGGKGLFVKELETALLENRSDIAVHSTKDVPMELPEGLV
LGVICKRHDPCDAIVFPKGSNLKSLEDLPHGARVGTSSLRRQCQLLLKRPDLKFLELRGN
VNTRLAKLDSGDYDAIILAAAGLKRLGFSDRVLPGETNIIDPNVMCPAAGQGALSIELRT
NDPEIAALLEPLHHIPDAVTVACERAMNRRLNGGCQVPISGFAQLKDGQLRMEARVGSVT
GKGPLIIQSKTFRLPWSGRTWPQLQKESEALGVEVADMLLADGAQAYLDEAYASRTLGWA
>Q17W61|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter acinonychis (strain Sheeba)|Swiss-Prot
MGKLVIGSRGSELALWQANYIKERLKKECFIESEIQIVKTTGDKILDAPLNKIGGKGLFT
KELEELLLKGTIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSTKFPDLMSLPKGA
KVGTTSLRRSMQLKCKRKDLDTESLRGNVQTRLKKLESGEFDAIILAEAGLCRLNIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFTALQKLNDEESAFCCHLEREFIKGLNGGCQ
IPVGVHASLMGEKVKIQAILGLPNGEEVIAKEKQGDKNKAFDSVQELLEAFLQSGAREIL
EKVQLF
>A0AJ05|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)|Swiss-Prot
MKRKIIVGSRRSKLALTQSNWVINKLKEQYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSNSTIDFAVHSMKDVPSSLEEGLVIGAIPKRESPLDCFVFNQVSSLDDLPK
GAIVGTSSLRRAAQLLKHRPDFNIRPIRGNIDTRLQKLHVENFDAIILAKAGLARMGWLE
NTTLKLEDIAPEVCLPAVGQGALAIECRESDQLIRDMLATIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATKIGEQIHFKGLVGNADGSKILESKEIGENPGQIGNKVAEVLLSEGAE
TIIEELRNK
>A1T3D3|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)|Swiss-Prot
MIRIGTRGSLLATTQAGTVRDALIAAGHDAELVIVSTEGDQRADAPIAEIGVGVFTAALR
EAIADGLVDAAVHSYKDLPTAPDPRFMIAATPVREDARDALVARDGLVLGELPAGSVIGT
SSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGELDAIVVARAGLARIGRLDAVTEAL
EPVQMLPAPAQGALAVECRAGDTALAQVLSQLDDADTRAAITAERTLLAELEAGCSAPVG
AIAEVVESIDEDGRVFEELSLRGCVATLDGSDVIRATGIGTPDRARELGLSVAEELFELG
ARDLLDEGGRDR
>Q6L2G8|hydroxymethylbilane synthase|EC 2.5.1.61|Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)|Swiss-Prot
MHIRIGTRSSKLAMIQAMMVKDRLDSLGIETEVKGFTSKGDINLDSPLYSIGGTGVFVDD
LNRMILKNEIDIAVHSAKDIPSFIDDSLEISAVLKRDDPRDVLISQHSLNDLEASSVIGT
SSLRRIKELKTLRNDILIKDLRGNIDTRLKKLDNGDYDGIIMAKAAYDRMRINRRHFILN
YDDFVPAPNQGIIAIISKKDSEINDVLKKINDDETYNDMKAERLILSGLNLGCSKPVGIY
AHKNRIFMRFYSLKNDDYKDIVMDYNNIDLEFIRSEIHDYGY
>B1J1V2|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas putida (strain W619)|Swiss-Prot
MSTREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDAPLAKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNRFSSLDALP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
ERITASISVDDSLPAGGQGAVGIECRSADSEIHALLAPLHHTDTADRVVAERALNKHLNG
GCQVPIACYAVLEGEQLWLRGLVGQPSGGTLLMADARAPRASAETLGVQVAEDLLGQGAA
AILKEVYGEAGHP
>A1AX51|hydroxymethylbilane synthase|EC 2.5.1.61|Ruthia magnifica subsp. Calyptogena magnifica|Swiss-Prot
MNKTLKIATRQSPLALWQAQNVKIRLEKHHPDLTVILVEMTTKGDQILNSPLSKIGGKGL
FIKELEVSMMKGITDIAVHSMKDVPYEIPQGFKLGAILKRENPFDAFVSNDFSSIDDLPQ
NAKVGTCSIRRIVQLKAIRPDLKILDLRGNVNTRLKKLDKGGFDGIILACAGLIRLGFES
RIKQQISDQQSLPAVGQGVVGIEIRENDTEILDLIKPLIDVETTYMVSAERAMNARLEGG
CSVPIAGFALIDNEQIMLTGLVGNVDTGVILKEQILSHVSQAEALGVELANKLISLGAKD
ILKN
>A6U2D8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain JH1)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q976H1|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)|Swiss-Prot
MRIRIAARGSKLSRIQVMMVENYLHKLGIETEFIEIKTKADLFQNEPLSKLGKGVFEKEV
NQAVLDNKADVAVHSMKDILTEISENLEIYAVLPRDPPFDILISRKNLFNLEPNSIIGTS
SIRRKNFLTFYRNDLNIKDLRGNIDTRLKKYFEGQYDGIIIAEASIYRLKEQVQYYRLDP
HLFTPEANQGIIVVIGRKKDETIKKIFNEINDKDTLEIAIAERKALSIVGGGCHSPIGVY
FEKYDKDFHGIISSSFGRKKITIEEYFHNMTPYEAGELLGKRFLEEIKNEGIIP
>Q7MQC7|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio vulnificus (strain YJ016)|Swiss-Prot
MTHSTPIRIATRKSPLALWQAYYVKDALQKAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYHHVDEL
PQGAVVGTCSLRRQCQLKAYRPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRTNDERILKLLEPLNHADTADRVKCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEIRGPRAQAEQLGVQLANQLLDEGA
REILTKLYQDHE
>A6VL87|hydroxymethylbilane synthase|EC 2.5.1.61|Actinobacillus succinogenes (strain ATCC 55618 / 130Z)|Swiss-Prot
MQQEILKIATRQSPLALWQANFVKDRLTEIYPDLTVELVPMVTKGDVILDTPLAKIGGKG
LFVKELENALLNGDADIAVHSMKDVPMEFPAGLGLSVICKREDPRDAFVSNRYRTLDDLP
PGAIVGTSSLRRQCQLKKRRPDLNIRSLRGNVGTRLSKLDQGDYDAIILASAGLIRLALP
ERIASFIETEISLPAAGQGAVGIECRINDQRVQKLLAPLADTETTACVLAERAMNNRLQG
GCQVPIGGYAVLNGNELHLRALVGALDGSKIIRAEGKSAVENAEVLGIQIAESLLAQGAD
KILAEVYNG
>Q65GK1|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus licheniformis (strain DSM 13 / ATCC 14580)|Swiss-Prot
MRNIIVGSRRSKLAMTQTKWVIKKLEELNPDFTFEIKEIVTKGDRILDVTLSKVGGKGLF
VKEIEQAMLSGEIDMAVHSMKDMPSVLPEGLMVGCIPKREDARDVLISKGRQKLADLKQG
AVVGTSSLRRSAQLLQMRPDLEIKWIRGNIDTRLKKLETEDYDAIILAAAGLSRMGWKDD
VVTEFLDPESCLPAVGQGALAIECRGSDEELLSLFSRLNDRYTQLTVTAERAFLHAMEGG
CQVPIAGFAKMDEDGVIELTGLVASPDGKTVYRETVKGKDPEAVGRECAAVMSEKGAKAL
IDRVKQELEDHEA
>A2SAH5|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei (strain NCTC 10229)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>B3EIN1|hydroxymethylbilane synthase|EC 2.5.1.61|Chlorobium limicola (strain DSM 245 / NBRC 103803)|Swiss-Prot
MKKQLIIGTRSSPLALWQAEFTKAELSRHFPELDITLKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKHLIAKEIDLAVHSLKDVPTSTPEGLIITSFTEREDTRDVIISKGGAKLADLPL
NAKVATSSLRRMSQLKSLRPDFEICDIRGNLNTRFKKFDEGEFDAMMLAYAGVFRLNFSD
RISEILPHEIMLPAVGQGALGIETRVDDEQTREIVRILNHSNTEYCCKAERALLRHLQGG
CQIPIGAYASFKNGTLKLLAFVGSVDGTVGINNEITRSGLTSPDQAEEAGIALAEELLKQ
GADKILSEIRKTR
>Q48AW8|hydroxymethylbilane synthase|EC 2.5.1.61|Colwellia psychrerythraea (strain 34H / ATCC BAA-681)|Swiss-Prot
MNNTTVRIATRKSALALWQAEYVKAQLEHFHDGINVELVPMTTKGDIILDTPLAKVGGKG
LFVKELEVAMLEDRADIAVHSMKDVPVDFPEGLGLEVICPREDPRDAFVSNTIKSLSDLP
QGSIVGTSSLRRQCQLKASRPDLDIRDLRGNVNTRLRKLDEGQYDAIILAAAGLIRLEMS
ERIAQFIEPEEMLPANGQGAVGIECRNDDATIKALLAPLECATTRIRVLAERAMNRALQG
GCQVPIGSYGVISADGKNIHLRGLVGSVDGSEMIESEITGPVEEGEALGNKLAQELLSRG
ADKILQQVYSENDIKNS
>B7MH66|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O45:K1 (strain S88 / ExPEC)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q5NI31|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)|Swiss-Prot
MKQITIASRESKLALWQTNFVKNRIQLELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>Q0BX92|hydroxymethylbilane synthase|EC 2.5.1.61|Hyphomonas neptunium (strain ATCC 15444)|Swiss-Prot
MTQIDPPKGGKRLRLGTRGSPLALAQAHQIADGIRAASAGAYDCEIVAFTTTGDKLTTER
LINSGGKGLFTRELDDALSRGELDLAVHSLKDVPSVLPPGQIFAAFPKREDPRDGFLSHG
AKSIQDLPEGATLGTASLRREAQALALRPDLKVVTFRGNVATRMRKLEEGLADATFLAMA
GLTRLGLSEVATPIPLEDMLPAAGQGIIGVVTRDDVDTELLEILGQLSHEPSRVAAIAER
AFLEKLDGSCRTPIAAHLFDRGDEWQLIGEVLSPGGTTRWRGDGVCRKDATDAQLVLLGR
AVAQEIIFAAKEALPVFGDER
>Q57989|hydroxymethylbilane synthase|EC 2.5.1.61|Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)|Swiss-Prot
MIRIGTRGSKLALYQANKVAELLKNLGYKVEIKIIKTTGDRVLDKKLSDIGIGVFTKELD
LAMLNNEIDIAVHSLKDIPTIWNENLMVGAVLERDSYHDLLIWNKDIDFNEDSKIVIGTS
SMRRRAFLKFIYPNAKFELLRGNVDTRLRKLKEGLYDAIVLSEAGIIRLGVSLEDFNYKR
LDILPAPAQGIIAVACKRDDEEMKSILKEINHERTYLESLCERTALNEFGGGCSVPFGAL
AVYDEKNELLKLKAAVVTNDELKNASGEVKCKIDEIDKAVELGKKIGLKLKN
>Q3SVF3|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391)|Swiss-Prot
MQSSDETDILATIGTRGSPLALAQAHEVRDRLARAHQVAPERIAIKTIRTSGDAIQDRPL
FDVGGKGLFTKEIEEALLAGTIDFAVHSSKDVPTFLPDATWLPAFLPREDVRDVFISPHA
GSLNDLPAGATVGTASLRRQAMVLKLRPDLKVNSLRGNVETRLRKISVGEADATLLALAG
LNRLGLQDKATRILETDEFLPAVGQGAIAIESRRDDDRINAFVKAIGDPETEVALSAERS
FLALLDGSCRTPIGGHCRVNGDRIDFRGLIISPDGTEFYETTREGARADAAALGADAAHE
LRERAGEKFFTLFAGA
>Q7VD89|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)|Swiss-Prot
MALDQVRIASRRSQLAMVQTNWVKEELEKACPSIDISIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLIGRADIAVHSLKDLPTNLPEGLMLGCITKREDPADALVVNKKYKNYQLN
DLPEGSVVGTSSLRRLAQLRHHYPGLIFKDVRGNVITRLEKLDSGEYDCLILAAAGLTRL
GFGNRIHQLIPSEISLHAVGQGALGIECVKDKEEILQIIKVLEHKESSLRCLAERAFLKE
LEGGCQVPIGVNSKIQGQELILTGMVASLDGKQLIRDTKTGSSMHPETIGIELANTLKSQ
GAMEILEVIFKEARA
>Q98EI7|hydroxymethylbilane synthase|EC 2.5.1.61|Rhizobium loti (strain MAFF303099)|Swiss-Prot
MQTTLKIGTRGSPLALAQAHETQARLMAAHGLPAEAFEVVVISTSGDRIQDRPLSEAGGK
GLFTKEIEEALLAGAIDIAVHSSKDMPTQLPDGLELSAFLPREDARDAFVGKAAKTIADL
LRGAKVGSSSLRRQALIRRMRPDLDVVMFRGNVQTRLRKLDEGVAAGTILAYAGLKRLGL
EHVATDLMPLDIFPPAPGQGAIGIETRIGDRAVEKMLVAIHDVPTGQALACERAFLAALD
GSCRTPIAGHATIETGNLSFAGLIISPDGTQSHTVELQGPAQDAARIGDEAARTVRAKAG
EKFFDGWV
>A8G848|hydroxymethylbilane synthase|EC 2.5.1.61|Serratia proteamaculans (strain 568)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQQRLMANHPGLQVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPVDFPAGLGLVTICERDDPRDAFVSNRFTSLDQLP
QGSVVGTSSLRRQCQLRERRPDLIVRDLRGNVGTRLSKLDNGDYDAIILAVAGLKRLGLE
QRIRSPLSPEECLPAVGQGAVGIECRLDDETTRALLAPLNHAVTETRVRAERAMNTRLEG
GCQVPIGSYAELDGDSLWLRALVGSPDGSQMVRGERRGPAALAEQMGIELAEELLAQGAR
EILQDVYQGNPPA
>Q6G8Q5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain MSSA476)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>P73660|hydroxymethylbilane synthase|EC 2.5.1.61|Synechocystis sp. (strain PCC 6803 / Kazusa)|Swiss-Prot
MTVSTSAPTVRIGSRKSQLALVQTYWVQEELQKHFPDRQFDVETMETQGDKILDVALAKI
GDKGLFTQELEDGMLGKRTDLAVHSLKDLPTNLPAGLMLGCVTKRVNPADALVLNAKHQG
KDLASLPEGAVIGTSSLRRLAQLRYHFPHLTFKDVRGNVNTRLAKLDSNEYDAIILAAAG
LERLDMANRIDQLIPPEISLHAVGQGALGIECREGDQEILSLLKVLEDENSRDRCLAERA
FLRQLEGGCQVPIGVNTHLDGDNLTLTGMVASLDGQRLIKDTLSAPRKEAEKLGQDLALK
LREQGAGEILAEILAEAGRG
>Q5GVL2|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)|Swiss-Prot
MTTLRIATRKSPLALWQSEHVAAALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGDKGLF
LKELELAMLRGDADCAVHSFKDVPMELDDPFVLPAILERGDPADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLDER
ISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAALARWEGEGLFLQGMVGSASDGRLIHADAHGSADDTQDLGRRVAQGLFDKGAAQL
LAAL
>B7JBH8|hydroxymethylbilane synthase|EC 2.5.1.61|Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB 8455)|Swiss-Prot
MPHSLRIGTRASPLAVWQAEHVRAALLRLHPGMAVEIITMTTSGDVLLDAPLHALGGKGL
FVKEIEDALQQRRVDVAVHSMKDVPALQPDGLEIVAIMAREDVRDAFVSNTFLHPDALPE
GARVGSSSLRRRAQLLERYPHLRVEDLRGNVATRLRRLDEGHYDAIILAAAGLKRLGLPD
RITHLLDIDRSLPAVGQGAIGIEARSDDRRTRELLAPLADADTQNCVLAERSMNQVLGGD
CRLPVAALARWQGPQMLLRGLVATPDGRRVLHAEAKGSDPVALGMAVAAALVAQGAAEII
EDVRNA
>Q9K8G0|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)|Swiss-Prot
MRKIIIGSRRSQLALTQTEWVISKLKEAGAPFDFEIKKIITKGDQILDVTLSKVGGKGLF
VKEIEQAMANKEIDIAVHSMKDVPSVLQEGFALGATTTRVDPRDALISNEGYTLAELPAG
SIVGTSSLRRSAQILAKRPDLEVKWIRGNIETRLRKLKEEDFDAIILAAAGLERMGWSNE
IVTEYLDPDLCVPAVGQGALGIECRADDDEVLEMLKTINDDTTAKTVLAERTFLHRMEGG
CQVPIAGYATLTDEGEIELTALVGTPDGEQIFKEILRGKDPVQLGETMAQALMDQGAKEV
LEQVKKGLESQ
>Q0BCU9|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)|Swiss-Prot
MNSETISAQAPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELENALADGRADLAVHSLKDVPMALPDGFALTAIMEREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARYPHLDVLPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLEARIRTLIDVEDSPPAAGQGALGIEIATHRTDVAAWLAPLHDPRTALAVEAER
MVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGQRVLTAEECGAVMTVADALALGRA
VSDELEAQGALDIVNALLAASQAGKGDA
>Q0ST16|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium perfringens (strain SM101 / Type A)|Swiss-Prot
MELIIATRKSKLAQVQTEKVMELLKKKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVK
EIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGAR
IGTSSIRRAEQLKLFRDDLEIVPIRGNVQTRIKKITEENLDGIILAAAGLKRLGMEDVIS
DYFDPKVFLPAIGQGALGIECLKDGEFNDYFKALDSKEVRTTVEAERSFMKVLNGGCHSL
IGAYSEVKDNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILGEV
>Q54P93|hydroxymethylbilane synthase|EC 2.5.1.61|Dictyostelium discoideum|Swiss-Prot
MSSITKRDKVIIGSRKSQLAMLQTEWVRDRIQELNPGIIVEIKTMDTTGDKVLDVSLSKI
GDKGLFTKELEDMMLNGTIDLAVHSLKDIPTKLPDGLKLGAITKRYNTSDAFIANAKKHG
KNCKLSELPQGAMIGSSSLRRVAQLKKAYPHLQFKDIRGNLNTRFKKLEDDSNGYDGMIL
AVAGLERMELTDHISEIIPDSISLYAVGQGSLGIECKDGDDFIQSILNPLIHRESMYCCE
AERSMLRDLEGGCHVPIGVVTKLHNQSQPDETLEINAIVLNLDGSKYIESKIIGPSIQYY
QLGKSIAQDLINKGSKDILSEFIKK
>A0Q481|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. novicida (strain U112)|Swiss-Prot
MKQITIASRESKLALWQTNFVKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEIAMLNNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
IVGTSSLRRKAQLLHYRDDLEIRDLRGNVQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>P08397|hydroxymethylbilane synthase|EC 2.5.1.61|Homo sapiens|Swiss-Prot
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTG
DKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPH
DAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHD
PETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIH
VPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDVARQLNDA
H
>Q602K3|hydroxymethylbilane synthase|EC 2.5.1.61|Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)|Swiss-Prot
MRGSSFPGFPSTVASHTLRIATRKSPLALWQAEYVASRLRAAHPDLRVELVGMTTRGDKL
LDAPLAKVGGKGLFVKELEQGLLEGRADIAVHSMKDVPVEFPEGLHLAAILEREDPRDAL
VSHRYRSFAELPADARIGTSSLRRQCQIKCRLPGCSLYDLRGNVNTRLAKLDAGEFDAIV
LASAGLKRLGFQERIAETLTPEQCLPAIGQGAIGVECRSTDTRTNALLVPLHHPPTAWCV
LAERAMNRRLDGGCQVPIAGFAQLEGDTLSLRGLVGNPDGSGIIRAEAVGHPSTFEALGK
RVAEHLLDQGADEILRRVYATP
>A9A1A1|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrosopumilus maritimus (strain SCM1)|Swiss-Prot
MKYIVGARGSQLSVAQTNLVIAELKKAHPDTEYEIKTITTKGDTDSRPLFTIDQKGIFEK
EIDRAVAQKEVDFAVHSLKDVPSELDDNLVLACIPKRETVNDVFISPDGSTLDSIKPGSV
IGTSSLRRAVQVSRKRPDVTVKPIRGNIETRIKKASGENYDAIVLAKAGISRLGVDVKYT
ELSTDDFSPSPGQGAIAIVARADDSKTIEMLKKIEDPDSRLEIEAERALSDFVDSGCRFP
VGAYAKSNGSEMTLTVTAFSVDGKQFLHVSKTGDKNNPKSLGQSAGEELREKGVNDLALN
WREKVEEWNKT
>A2BVF7|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain MIT 9515)|Swiss-Prot
MTKLKLKIASRRSKLAMVQTLWVKEQLEKNIPNLEVSIESMATQGDKILDVALAKIGDKG
LFTKELEAQMLIGKADIAVHSLKDLPTNLPDGLKLGCITKREDPSDALVVNKKNEIYQLE
SLPAGSIVGTSSLRRLAQLRYKFPYLNFKDIRGNVITRIEKLDSGEFDCIILAAAGLKRL
GFESRIHQIIPNEISLHAVGQGALGIECKSEDKEVLKIISVLEDKASSQKCLAERSFLRE
LEGGCQVPIGVNSSIQNDEICLKGMVASIDGKKLIKDESSGNVKYPEEVGKKLAEKLKLQ
GADKILSEIFEQFRDK
>Q8XWW3|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia solanacearum (strain GMI1000)|Swiss-Prot
MSSNARPTSVESPLAAQAPTKLVIASRESRLAMWQAEYVRAALQKYYPACDVSILGMTTR
GDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMELPPGFVLSAILEREDP
RDAFVSNDYADLAALPAGAVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLSKLDRGDY
AAIILAAAGLKRLGLSERIRAVIAPETSLPAAGQGALGIESRVDRHDVQAWLAPLHHAPT
ALAVTAERAVSRQLGGSCQVPLAAFAQWTDAGALRLRAFVASPDGRRKLAAEAEATPATP
AEAEALGARVAQQMLDGGAHDILATLGADAPPAT
>P0A1Q8|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>P64341|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain N315)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q3ALS9|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain CC9605)|Swiss-Prot
MALTELRIASRRSQLAMVQTNWVKAELEKAHPGLKITVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVDRADIAVHSLKDLPTNLPEGLMLGCITEREDPADALVVNAKNQAYKLE
TLPEGSVVGTSSLRRLAQLRHHYPHLIFKDVRGNVITRLEKLDSGDYDCLILAAAGLGRL
GFSDRIHQLIPGEISLHAVGQGALGIECVEGKPEVLEAIKVLEHTPTSQRCLAERAFLRE
LEGGCQVPIGVNTRFEGDQLILTGMVASLDGKRLIRDQTSGEASEAEAIGIALANTLKGQ
GAGEILKEIFETVRPEA
>Q2NYU4|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas oryzae pv. oryzae (strain MAFF 311018)|Swiss-Prot
MTTLRIATRKSPLALWQSEHVAAALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSFKDVPMELDDPFVLPAILERGDPADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLDER
ISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAALARWEGEGLFLQGMVGSASDGRLIHADAHGSADDTEDLGRRVAQGLFDKGAAQL
LAAL
>Q6FFA9|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter sp. (strain ADP1)|Swiss-Prot
MISILMQTLKIATRQSPLALWQAEHIRDRLQALYPELKVELVKFVTQGDKILDTPLAKIG
GKGLFVKELEAALLDGRADLAVHSMKDVPMHLPEGLSLAVICEREDPLDAFVSNHVMSFD
QLPLGARVGTSSLRRKCQILKQRPDLEIIDLRGNVGTRLAKLDDGQYDAIVLASAGLKRL
GLISRIRHSINAEISLPAVGQGALGLECRANDKKILDLIAPLAHQPTSACVRAERAFNAY
LEGGCQVPIAGFATLTQECLTLEGRVGSVDGKTLLKDHVEGHADQAEVLGVQLAKQLLAQ
GAGELLRDLYQ
>Q817R0|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain ATCC 14579 / DSM 31)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDND
VITEHLDDTLCVPAVGQGALAIECREDDKDLLQLLAHINDTITERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTNPEEVGLEAADRLIKQGAKEL
ILAANKEQQ
>B1JWR0|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia cenocepacia (strain MC0-3)|Swiss-Prot
MNSETPAAGPQQAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQ
ILDRTLSKVGGKGLFVKELEAALADGRADLAVHSLKDVPMALPDGFSLAAIMEREDPRDA
FVSNDYASLDALPAGAVVGTSSLRREAMLRSRYPHLEVLPLRGNLDTRLAKLDRGDYAAI
ILAAAGLKRLGLEARIRALLDVEASPPAAGQGALGIEIAAHRDDVAAWLAPLHDPQTALA
VEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGKRVLTAEECGAVVTVADAL
ALGRAVSDELEAQGALDIVQALLAGSQAAGKGDA
>B8GXG1|hydroxymethylbilane synthase|EC 2.5.1.61|Caulobacter crescentus (strain NA1000 / CB15N)|Swiss-Prot
MSRQPPIRIGARGSKLSLAQSGLMQARIAHALGVPAGASKDEIEAAAPLIPIVTSGDRIQ
DRRLMEIGGKGLFTKEIEEALLDGRIDCAVHSLKDMPAELPPGLVLAATPEREDPRDAFI
SHVCERLEDLPKGARLGTASLRRQAQALHVRPDLEIVMLRGNVDTRLAKLERGEADAILL
AQSGLNRLGLGHLTRSWLDPDACPPAPGQGALVIETRAEDIGAPWLEAVRCRQTTIAVAA
ERGALLALEGSCRTAIGARAILDGARLSMIVEALTPDGAQRFRREGDITLTGADDIAEAR
AFGLTLGAEVRAAGGDAIILPE
>Q0TQG4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)|Swiss-Prot
MELIIATRKSKLAQVQTEKVMELLKEKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVK
EIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGAR
IGTSSIRRAEQLKLFRDDLEIVPIRGNVQTRIKKITEENLDGIILAAAGLKRLGMEDVIS
DYFDPKVFLPAIGQGALGIECLKGGEFNDYFKALDSKEVRTTVEAERSFMKVLNGGCHSL
IGAYSEVKDNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILGEV
>B8DKW2|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)|Swiss-Prot
MKKLVIATRGSKLALWQAEHVKSCIEGQHPGVSVELLVLKTRGDIILDVPLAKVGGKGLF
VKEIEEALLDGRADLAVHSMKDVPMELPEGLVLGIIPEREEPSDTFLSVHHDSLAALPHG
ATVGTSSLRRQSQLLALRPDLNVVSLRGNVDTRLRKLSEGQFDAIIMATAGMKRLGLSAP
RSEVLGPPAFLPAVGQGALGIEFRADRADLHELLAFMEHTPTRIRVEAERGFLAGLQGGC
QVPIAGHAVMTGDGTFALEGLVADLTGARVIRRTMNGVSAPDGAQARQIGLDLAAQLVAD
GAGEILAEVYGSGEAVN
>Q2A5R3|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. holarctica (strain LVS)|Swiss-Prot
MKQITIASRESKLALWQTNFVKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>B2US69|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain Shi470)|Swiss-Prot
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLERAFVKGLNGGCQ
IPIGVHASLMGDRVKIRAVLGLPNGKEVIAKERQGDKTKAFDLVQELLEAFLQSGAKEIL
EKAQLF
>Q46CH0|hydroxymethylbilane synthase|EC 2.5.1.61|Methanosarcina barkeri (strain Fusaro / DSM 804)|Swiss-Prot
MIIGTRGSQLALAQAETVARLLKAKGVETSLKIIKTSGDRFTDRPLHAVSSGVGAFVREL
DEVMLEGKIDIAVHSMKDMPTIRPPTLPTVAVLKRDTPFDLLLTYDGTPLDELSEQSIIG
TSSLRRAAQIKRYRPDLVTQDLRGNIDTRLRKLKEGKYDGILLAKAGLERMGWELEGEIL
SPDFFCPSPNQGTIAVVTRAETEAEAAVSRLDHTDSRIATEIERILISELGGGCTTPIGS
YAEIMPDRKKLHVRAEVLSLDGEETVGINEFIPMAGGIEKARELGSSLVHMGGKKLADEA
LMQLSRDSCDSNDLHE
>Q82WS2|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298)|Swiss-Prot
MSSPKKIVIASRESQLALWQANFIRGRLLELYPQTDITILGMTTKGDQILDVSLSKIGGK
GLFIKELELALEDGRADIAVHSMKDVPMIVPSGFTLAAITEREDPRDAFVSNDFSSLEEL
PAGSVVGTSSLRRESQLRARFPHLQVRPLRGNVQTRLRKLDEGEYSAIILAAAGLKRLEL
GYRISMLLPPELSLPAVGQGALGIECRDNDPDMVEWMKPLHHAATACCVEAERAMSRMLG
GSCQVPLGGFAEIFEDVLTLRGFVATPDGSRMIADKLCGKPESGEQVGQQLAQNLKAHGA
EEILAALA
>A2C7L8|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain MIT 9303)|Swiss-Prot
MVLTQLRIASRRSQLAMVQTNWVQAELEQAHPGLSISVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLIGRADIAVHSLKDLPTNLPEGLMLGCVTEREDPADALVVNQKNAEHQLD
TLPEGAIVGTSSLRRLAQLRHHYPHLVFKDVRGNVITRLEKLDAGNYDCLILAAAGLTRL
GFGDRIHQLIPSEISLHAVGQGALGIECVEGHPEVLEVIKALEHKPTAQRCLAERALLRE
LEGGCQVPIGVNSRIEANELLLTGMVASLDGKRLIRDQQRGPIDRCEAIGKELAETLKSQ
GAGEILAEIFAAVRPEA
>A3MWV7|hydroxymethylbilane synthase|EC 2.5.1.61|Pyrobaculum calidifontis (strain JCM 11548 / VA1)|Swiss-Prot
MKIRVATRGSKLSLLQTQELLDQVKAVEPKVEFELVVVKTTGDVVQDRPLYQIGVKGIFE
KEVNLAVLRGEADVAVHSLKDLPSELTPGLVIAGFSRRAPPYDVVASREGYSLYTLPKGA
VVGTSSVRRAEFLRAVRPDVEVRPLRGNVDTRVGKILSGQYDAAIMAMAGLVRLYGWEAP
VKLSPIRPEEIPPPPGQGIVVAVVKEGEAWLIDILRRASDRRAAVEATAEREFLMHVGAG
CHVAVGGLARYEDGGMSFVAGYASGGRRYVIKLWGEDPREVGRRAAEEIRKIREGD
>B4TNV3|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella schwarzengrund (strain CVM19633)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>A6QHK4|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain Newman)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q0I8I3|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain CC9311)|Swiss-Prot
MALEHLRIASRRSQLAMVQTNWVKAELEKAHPGLAISVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGRAEIAVHSLKDLPTNLPEGLMLGCITEREDPADALVVNSKNAEYTLE
TLPEGSIVGTSSLRRLAQLRYHYPHLQFKDVRGNVITRLEKLDSGNYDCLILAAAGLSRL
GFGDRIHQSIPGNISLHAVGQGALGIECVCDRPEVMELIQVLNHAPTSARCLAERAFLRV
LEGGCQVPIGVNTQIEGDTIQLTGMVASLDGKRLIRDEQAGPLADPEAVGRDLAHKLKDQ
GAGEILQEIFEMERGQ
>B0RNI9|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas campestris pv. campestris (strain B100)|Swiss-Prot
MTTLRIATRKSPLALWQSEHVATALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDAPFVLPAILERGDPADALVSNLYATLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEAR
ITARLDAPEWLPAPAQGAVAVECRGDDARIHDLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAAFARWEGEDLFLQGMVGSASDGRLIHAEAHGSPDATEDLGRRVADGLFEKGAAQL
LAEL
>Q9WX16|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)|Swiss-Prot
MTEKALRLGTRRSKLAMAQSGQVADAVSQVTGRPVELVEITTYGDTSREHLAQIGGTGVF
VAALRDALLRGEVDFAVHSLKDLPTAQHEGLVVAAIPEREDPRDVVVARDARKLTDLPRG
ARVGTGAPRRMAQLNAYARTHGMEIETVPIRGNVDTRIGYVRSGELDAVVLAAAGLNRVG
RIDEVTDFLSVDTVLPAPGQGALAVECAADNASLIAALAELDDPFTRAAVTAERSLLAAL
EAGCSAPVGALADLLADGQTVKEMRLRGVVGTTDGSTLVQLSTTGPVPETHEAALALGGE
LAAEMLAQGAAGLMGERAQ
>B7HQM4|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain AH187)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKEKVVGTDPEKVGLEAADRLINQGAKEL
ILAANKEQQ
>B8D8F3|hydroxymethylbilane synthase|EC 2.5.1.61|Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)|Swiss-Prot
MYNKTLRIATRKSPLALKQTKYVQKKILSLYPDLNIKLVPIVTHGDNILNKSLSKIGGKG
LFIKELELALLENKADIAIHSMKDLPVKITKELCLVSICKRGNALDSLVSNNYQSINQLP
KGAIVGTSSLRRQCQLITYRPDLIISPLRGNIETRIAKLDQGKYDAIILATEGLNRLRLK
NRITQIIPAELSLPSCGQGAIGIQSRLHDKKVLFFLSRLNHINTFIEINAERAFCRKLES
GCQIPIGSYAILKKNKIWLRGLVGSPNGKIILKGERIGCYNTGEKMGYSLADELLKNGAK
NILNNLHIKQSYCI
>O94048|hydroxymethylbilane synthase|EC 2.5.1.61|Candida albicans (strain SC5314 / ATCC MYA-2876)|Swiss-Prot
MPHHIMSINDSNHVQIGGRKSKLAVVQSEIVKKVIEDTFPNLSCSILALSTLGDKVQTQP
LYTFGGKSLWTKELEILLLDSVDEFPKLDLIVHSLKDMPTNLPEEFELGCIFQREDPRDA
IVMKQGSSYKSLKDLPAGAIVGTSSIRRSSQLIKNYPHLRFESVRGNIQTRLNKLDQPNN
EYCCLILASAGLIRLGLGHRITSYLDDMYYAVGQGALGIEIRKGDDNIKSILKKIEDPIA
TICCLAERSLMRYLEGGCSVPLGVHSDYNESKQELTLKGIIVSPDGTVSIEDEVIKRITC
DEDCEQVGIELGDKLKAKGAKEILDKIDMTRNINARPTEV
>Q59293|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium josui|Swiss-Prot
MKKIRIGSRDSKLAIIQSELIMSAIRKYDPDIELELITMKTTGDKILDKTLDKIEGKGLF
VKELDNALYNNEVDITVHSYKDMPLEENPELPVVALSKREDPRDAFILPQNGENGEPIGS
SSLRRQLQLKELFPGCKTAPIRGNVQTRLKKLDSGEFSAIVLAAAGIKRLGLESRIGRYF
SVDEILPAASQGIIAVQGRVGENFDFLKLFHSEESLCISLAERTFVREMNGGCSTPIAAY
ATIQGSEIILKGLYCNETTGELRKECVSGNRNNPVELGYELVKKMKSSKSI
>A8ZWG5|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfococcus oleovorans (strain DSM 6200 / Hxd3)|Swiss-Prot
MEIRIGSRKSSLAMWQTCYVEDKLKQSGITTSILPIDTRGDQVLNVAIAKIGSKGVFTEE
LEAKLADGDIDIAVHSAKDMPSVLPDGFELIAFTDREEPADVLVSHKKDLDISDSSRPVT
IGTSSVRRQALLGRFYPHVRTVDIRGNVQTRVLKMKEGLCDAILMAYAGIHRMGMDDLIV
HTFSPDTFIPPVGQGCIAVEASSRLAAEKKEAIRACINHPASETCLLAERAFLKRLEGGC
SIPAFALARLNGDRLTLSGGLMSLDGKKFIFNTRAGAGSQATAIGTDLGNHVLENGGAAL
LAEIRKQQTT
>B0TW04|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella philomiragia subsp. philomiragia (strain ATCC 25017)|Swiss-Prot
MKQIVIASRESKLALWQTNYVKDRIQQELNIRCQINTMKTQGDIILDKPLNKIGGKALFM
KELEIAMLNNKADIAVHSLKDVPYQLPQGFCLSSFMPREDPRDAFVSNKYSSIDDLPRGA
IVGTSSLRRKAQLLHYRYDLEIRDLRGNVQTRLSKLDNGDYDAIILASAGLIRLELNERI
TQFIPVEISLPAVGQGIVVIEALDKSSEILQKLQKLNCSDSFCVATAERAFNQELKGGCH
VAIGAYAELHDNQITLTAMVASSDGKNILKRKLTGDDPMRLGKLLAQEMIELGAYKILEK
>B5ZA04|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain G27)|Swiss-Prot
MGNLVIGSRGSELALWQANHIKERLKKECFIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCHLEREFVKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKRGDKTKAFDLVQDLLEEFLQSGAKEIL
EKAQLF
>Q65VX7|hydroxymethylbilane synthase|EC 2.5.1.61|Mannheimia succiniciproducens (strain MBEL55E)|Swiss-Prot
MNNKNHLKIATRQSPLALWQANYVKDRLTALYPDLQVELVTMVTKGDVILDTPLAKIGGK
GLFVKELEHALLNHEADIAVHSMKDVPMEFPQGLGLSVICKREDPRDAFVSNKYRSLAEL
PQGAIVGTSSLRRQCQLKSLRPDLDIRSLRGNVGTRLSKLDNGDYDAIILASAGLIRLGM
AERIASFIETDISLPAAGQGAVGIECRVDDELVQSLLAPLAHQETTICVLAERAMNNRLQ
GGCQVPIGGFAQVKNGEVFLRALVGATDGSQIIRAEGKSAVENAEVLGVQIAEDLLQQGA
DKILKSVYQD
>Q9JVS4|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)|Swiss-Prot
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>A3PBM0|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain MIT 9301)|Swiss-Prot
MTNFKLKIASRRSKLAMVQTLWVKDQLERNIPNLEVSIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGHADIAVHSLKDLPTNLPNGLKLGCITKREDPADALVVNKKNDCYKLE
TLPEGSIVGTSSLRRLAQLRNKYPHLIFKDIRGNVITRIEKLDAGEFDCIILAAAGLKRL
GFESRIHQIIPSEISLHAVGQGALGIECKSDDKKVLEIINILEDKPTSQRCLAERAFLRE
LEGGCQVPIGVNSNIQNEKLCLTGMVASLDGERLIKDQHIGNINDPEEIGKELAKKLKQQ
GAEEILSEIFEKFREK
>A1T0R0|hydroxymethylbilane synthase|EC 2.5.1.61|Psychromonas ingrahamii (strain 37)|Swiss-Prot
MTAQKIRIATRHSPLAMWQANFIKSELLKYHPNLIVELLPMKTKGDIILDTPLAKVGGKG
LFVKELEVAILEGRADIAVHSIKDVPVDFPEGLGLTTICKREDPHDAFVSNHYKQLDELP
EGAIVGTCSLRRQCQILALRPDIIIKNLRGNVNTRLRKLDEGEYDAIILAAAGLMRLEMQ
HRITSLIAPEVSLPAVGQGAVGIECRLDDEQTITLLKPLEDPETRIRITAERAMNLKLQG
GCQVPIGSFAILENEQLFLRGLVGSVDGKQIIRKEITGHQNDAQQLGITLAEQLLACGAE
EILAEVYKNQ
>Q5PKL7|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella paratyphi A (strain ATCC 9150 / SARB42)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>A5ITJ5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain JH9)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>A0LN73|hydroxymethylbilane synthase|EC 2.5.1.61|Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)|Swiss-Prot
MTDRVIRIGTRGSMLALKQSGNVKAAMEALWPGLRVELQVVRTTGDKILDVPLAKVGGKG
LFVKEIEDALLARTVDLAVHSMKDVPAILPEGLEIGAIPKREDPRDVIVTRTGKGIADLP
MGGRVGTSSLRRASQIRKLRPDIEIANLRGNIETRLRKLTEGAFDAIILAAAGLHRMGWQ
NRVTSYLDPADFLPAIGQGAIGIELRCDDGEVRELLAPLHDPDTHVAVEAERSLLRTLEG
GCQVPIGGHAHLVDGTLTLSGMVASIDGEELFRASRAGSPAQARKIGRDVGMELLDSGAR
RILEEIYRA
>Q8PPR3|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas axonopodis pv. citri (strain 306)|Swiss-Prot
MTTLRIATRKSPLALWQSEHVADALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDEPFVLPAILERGDPADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEAR
ISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRVCVEAERAMNRALHGSC
HVPVAAFARWEGQDLFLQGMVGSASDGRLIHADAHGSADDTEALGRRVAQGLFDKGAAQL
LAEL
>C1ETR0|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain 03BB102)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>B0CID9|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella suis (strain ATCC 23445 / NCTC 10510)|Swiss-Prot
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>B8I0Q8|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)|Swiss-Prot
MKKIRIGSRDSKLAIIQSEMVMAAIREFDPDIELELITMKTTGDKILDKTLDKIGGKGLF
VKELDYALYNNEVDITVHSYKDMPLEDNPKLPVVALSKREDPRDAFVLPQGEIAENNEPI
GSSSQRRQLQLKALFPNRKTAPIRGNVQTRLKKLDSGEFSAIVLAAAGIKRLGLESRISR
YFSVDEILPAASQGIIAVQGRAGENFDFLKLFHSEESLCISQAERTFVREMNGGCSTPIA
AYATIVESEIILKGLYHNEATGESKKECVSGSRQNPVELGYELVKKMESCRRI
>B8G2M2|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfitobacterium hafniense (strain DCB-2 / DSM 10664)|Swiss-Prot
MGSVKIGTRDSQLALWQAEWVKRKLEEYYPEREFVLVPMKTKGDKILDVPLAKIGDKGLF
TKELEVGLLNGEIDCAVHSLKDLPTVLPPGLEIAAFCEREEPRDVFLSKDGTPLGSLPAG
SIIGTSSLRRKAQLQNYRSDLSFADLRGNLQTRWRKLQESDMAGIVLAAAGVKRLGWEDR
ITEYISEEIMLSAVGQGAIAVEIAAQRADVREMLDLLNHGDTERAVKAERALLYRLEGGC
QIPIGAWAVTEQQQIVLKGMVASLDGQRILKVTLSGEHPEELGRQAADLLIAQGALEILQ
EIRTPLEK
>B1YJV1|hydroxymethylbilane synthase|EC 2.5.1.61|Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15)|Swiss-Prot
MRKIIVGSRSSKLAMTQTKWVIEQLKQAGAPYEFEIKNIITKGDRILDVTLSKVGGKGLF
VKEIEQQMIDEDIDFAVHSMKDLPSELPTGLIIGATPSRVDARDALITTTGGGLDSLPEG
AIVGTSSLRRGSQLLKLRPDLKIESIRGNIDTRLEKLKTGPFDGILLAAAGLQRMGWSED
IVSEYISTDDMIPAVGQGILAIECRANDQEVRDLLNLIHDQMTEKVAFAERSFLAAIEGS
CHVPVGGFATINEDLSTTLVGFLGSVDGQQILLERETSLDPMQLGQTVATRLLDAGGREI
LASLPDDL
>Q7VFE9|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter hepaticus (strain ATCC 51449 / 3B1)|Swiss-Prot
MAKQSGADRELVIGSRGSILALWQAEYIKSCLKAQCGLQSRIQIIKTRGDKILDVPLAKI
GGKGLFTKELEEMLLSKDIDLAVHSLKDVPVEFVPELDLAAITQRESANDCFLSVNYPNL
NALPQGAKVGTTSLRRSMQIKKYRSDLDTLSLRGNVQTRLEKLHNGAFDAIILAQAGVNR
LKINTQDVRYIVPLDFMIPAMGQGALGIEMRKDSIFFDRIAVLNDKQSALCVSAERAFVR
TLEGGCQVPIGVYAQFSNNKLTLQAIVGLPDGSEVLQDSVEDSINIDDINASENLGIAFA
QKFIDKGAKELLERAAKIAFA
>B1HVD6|hydroxymethylbilane synthase|EC 2.5.1.61|Lysinibacillus sphaericus (strain C3-41)|Swiss-Prot
MRKIIVGSRRSKLALTQTNWFINELKAAGAPFEFEVKEIVTKGDQILDVQLSKVGGKGLF
VKEIEQALYEKEIDFAVHSMKDMPAVLPEGLVIGCIPPREDARDAFISKGHVKFSELPAG
AVVGTSSLRRSAQLLTVRPDLEIKWIRGNVDTRLAKLETEEYDAIILAAAGLKRLGWSED
VVTEFLSVEDCLPAVAQGSLGIECREDDTELLDELAKLTDQLTWQEAHAERAFLAAMDGG
CQVPIAGYATSNGEEITLTGLVAAPDASVVYKETVVGSDAQKIGEELATILTKQGAFDLI
QRVKAEQDAK
>Q1D8Z8|hydroxymethylbilane synthase|EC 2.5.1.61|Myxococcus xanthus (strain DK 1622)|Swiss-Prot
MMTHVRIATRQSPLALWQARHVGALLTSRHPGLEVTLVEMTTEGDRFLSAPLSAVGGKGL
FVKEIEQALLDGRADIAVHSLKDMTSVFPEGLILAAVPEREDPRDVFCGLGGLTLDTLPQ
GARVGTSSLRRSCILRSRRPDVDIVSVRGNVQTRLARTREQGLAGALLAYAGLKRLGLED
VITQVLPPEVSLPAVGQGVLAIQCRTDDARVRALLVPLEHATTRIAVTAERALLAKLEGG
CTVPLAGYATVSGDTVFLRGLVGRPDGTHVVRGEVRGPVSQAHALGESLADDLLSRGAAD
ILRDFARRFEARES
>B4S922|hydroxymethylbilane synthase|EC 2.5.1.61|Prosthecochloris aestuarii (strain DSM 271 / SK 413)|Swiss-Prot
MKQQLIIGTRSSPLALWQAEFTKAELSKNFPELDIQLKLIKTTGDVLLDSPLSKIGDMGL
FTKDIEKHLLAKEIDLAVHSLKDVPTETPEGLILSAFTEREDTRDVIISKNGDNLKQLKP
NAKIATSSLRRTSQLLGIRPDFEMGDIRGNLNTRFKRFDESDFDAMILAYAGVHRLNFGD
RISEILPHDVLLPAVGQGALGIETRIDDEQTRQIVKVMNNQNSEYCTKAERALLRHLQGG
CQIPIGAYATYKNGTLHLSAFVGSVDGKRAIRNEITKENVTAPELAEKTGIELAEELMKQ
GANEILAEIRKI
>Q88B91|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. tomato (strain DC3000)|Swiss-Prot
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFESLDALP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYNAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGRVLLHADARAPQTSAQALGVQVAEALLAQGAA
EILKAVYGEANNE
>A9MJ10|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)|Swiss-Prot
MLDNVLKIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNQYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLA
SRIRTALPPEVSLPAVGQGAIGIECRLDDARTHALLAPLNHPQTALRVTAERAMNTRLEG
GCQVPIGSYAEIFNGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTAVYNGEAPA
>Q2FG66|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain USA300)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q2LQU2|hydroxymethylbilane synthase|EC 2.5.1.61|Syntrophus aciditrophicus (strain SB)|Swiss-Prot
MKIGTRGSALALTQTRQIAARLQGQYPEMHLEIVVIKTSGDIQKDVPLAKIGGKGLFIKE
IEEALLAGTVDLAVHSMKDLPAELPEGLQIAAVPRREDPRDVLISGICREFDNLPAGARI
GTGSLRRSVQLRDWRPDLEIVPLRGNLDTRIRKVAQAALDGVVVAAAGIRRMGWAEKVTQ
FIPTEKMLPAVGQGVLCLETREEDEDLKAGLAFLEDKRTRREVTAERAFLRRLGGGCTLP
VAAFAEQRGDVLTIRGMVGSLNERTMIRQEIYGSVEQAVDLGTELAERLLDGGGRILLEH
LEDGQP
>Q7M8L2|hydroxymethylbilane synthase|EC 2.5.1.61|Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)|Swiss-Prot
MNKIIIGTRGSVLALWQAEYVKAELERAHEGLSVELKIVKTKGDKILDVPLAKVGGKGLF
TKELEEMMLQGEIDLAVHSLKDVPVELIEGLTLSAITEREDVRDCFLSDKYASLETLPLG
AKVGTTSLRRSMQIKSMRSDLDTESLRGNVQTRIKRLKEGDFDAIILATAGVNRLDLWKE
VNYVIPIDTEMMIPAMGQAALGIECKEGSEAFRLTQILEDKKARIETTAEREFVRVLEGG
CQVPIGANAYLEGETLHLKVAVGLPDGSEILMDRLSAPKGEAVRLGRELAARLIAKGARE
LLRRAEEMAFQ
>Q82P95|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)|Swiss-Prot
MSGMSALELIRIVSRDSPMALAQVARVRAELAALHPRTRTEVVAVKTTGDKWMGDLSKVD
GKGAFTKEVDAALLAGEADLAVHCVKDVPADRPLPAGTMFAAFLKRDDIRDALVHPGGLT
LDELPPGTRIGTSSVRRVAQLAAAYPHLECVPFRGNANRRLEKLAAGEADALLLAVSGLE
RIGREDVITEVLEPETMMPPIGAGILALQCREGDTGLIETISELGDPGTHREATAERMFL
HVLQGHCNSPIAGYARTERNGELSLRASVFTLDGKTVLNAHEWAGRLDPATLGTSVAVAL
LRQGARELIDDIPH
>A7GTE5|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus subsp. cytotoxis (strain NVH 391-98)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLQALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPAGLTIGCIPKRVDPRDAFISKNGKSFKELAKG
ATLGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLQEENYDAIILATAGLKRMGWDND
VITEHLDESLCVPAVGQGALAIECREDDKDLLQLLAHMNDAATERTVAAERVFLHKLEGG
CQVPIAGYATLQENGKIKLHALVGSTDGSVLLKETVVGTNPETVGLEAAERLIHQGAKEL
ISAANKEQQ
>P57651|hydroxymethylbilane synthase|EC 2.5.1.61|Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)|Swiss-Prot
MYNKTLRIATRKSPLALKQTKYVQKKILSLYPDLNIKLVPIVTHGDNILNKSLSKIGGKG
LFIKELELALLENKADIAIHSMKDLPVKITKELCLVSICKRGNALDSLVSNNYQSINQLP
KGAIVGTSSLRRQCQLITYRPDLIISPLRGNIETRIAKLDQGKYDAIILATEGLNRLRLK
NRITQIIPAELSLPSCGQGAIGIQSRLHDKKVLFFLSRLNHINTFIEINAERAFCRKLES
GCQIPIGSYAILKKNKIWLRGLVGSPNGKIILKGERIGCYNTGEKMGYSLADELLKNGAK
NILNNLHIKQSYCI
>Q6FNR4|hydroxymethylbilane synthase|EC 2.5.1.61|Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)|Swiss-Prot
MTRESINIGGRRSKLAVVQSNHVRDLVQAKFPQYDCTVFTLQTLGDQIQFKPLYSFGGKA
LWTKELEDYLYCEDQEKRLDLIVHSLKDMPTLLPDGFELGCVTKRVDPTDCIVMPRGSPH
RCLADLPEGAVVGTSSVRRSAQLKRKFPHLKYQSVRGNIHTRLEKLDDPEGPFQCLVLAS
AGLVRMGLEDRITQRLHSDIMYHAVGQGALGIEIRQGDKKILQILDEIADLESTVCCLAE
RSLMRTLEGGCSVPIGVESSYDHKTKKLLLKGIVVNVEGTMAIEDQQEVVVNDIREDSIK
CGVLLAHKMIKDGAKKILDEINLERVIQQ
>B9DZL6|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium kluyveri (strain NBRC 12016)|Swiss-Prot
MSFRIATRKSKLALVQTDYVIDLLALKFKMQCEKVLIRTEGDRKLDVSLDKIGGKGVFVK
DIEKALIEKRAQAAVHSMKDMPNELLDLFEIIAMPVREDVRDVFISPEGIKFLDLPKGAV
IGTSSIRRAVQIKNLRHDIEIVPIRGNIETRVRKMKEEKLDGIVLAAAGVKRLGMSEIIT
EYFNPFEFIPAVGQGAIGVEILKNSEYASTLGKIDNEDIRMGVEAERSFLKKLQGDCHTP
VGAYSVIEGEILNITGIFQVGNKLIKKDVCGDKWDYIALGESLGEKIISG
>A4J6H7|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfotomaculum reducens (strain MI-1)|Swiss-Prot
MKHKITVGSRDSALALWQTRWVVEQLEKQNPDVTFEITTMKTKGDKMLDVALAKIGDKGL
FTKELEVAMLQKEIDFAVHSLKDMPTALPEGLIIGAVCKRDNPGDALISKDGRKLDELPK
GARIGTSSLRRCAQLLNYRPDFQLEALRGNLNTRMKKLVSEQLDGIILAAAGITRMGWED
MIAEIIPFQVCLPAVGQGAISVECREDDPEILNLLKGIEHTETKAATEAERSLLRYLEGG
CQVPIGAHSEVKNNRLMLTAVVATLDGTKVIRAQGENEVNKAVELGIEVAEKLMAMGGKK
ILEEVRAGE
>Q14JI3|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. tularensis (strain FSC 198)|Swiss-Prot
MKQITIASRESKLALWQTNFVKNRIQLELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>Q1CUR5|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain HPAG1)|Swiss-Prot
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFITLQKLNDEKSAFCCRLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>A1TXW9|hydroxymethylbilane synthase|EC 2.5.1.61|Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)|Swiss-Prot
MSKRTLRIATRSSALALWQAEFIKAELERLHDNVDVELIKIKTQGDKILDVPLAKIGGKG
LFVKELEEAMLDGRADLAVHSMKDVPMEFPEGLGLVAICEREDPTDAFVSNQYEHIDQLP
EGAVVGTASLRREAQLRANRPDLQIKVLRGNVNTRLAKLDAGEYDAIVLASSGLKRLGFH
DRIRYCLPDTFSLPAVGQGALGIECRVGDTELLELIDPLNHTDTWDRVSAERALNRRLEG
GCQVPIAAYALLEDDNTLWLRGLVGAVDGTQIFRVEGRAPRAEGERLGRELAEQLLSMGA
DKVLAEIYGHTPR
>Q9K0P6|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup B (strain MC58)|Swiss-Prot
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>A2C0V4|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain NATL1A)|Swiss-Prot
MTLDQLRIASRRSQLAMVQTNWVRDELQRAHPDLAITIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLLGHAEIAVHSLKDLPTNLPEGLILGCITEREDPSDALVVNEKNQIHKLE
TLPEGSVVGTSSLRRLAQLRYHYPHLVFKDVRGNVITRLEKLDSGEYDCLILAAAGLQRL
GFANRIHQLIPTDISLHAVGQGALGIECVSGQQKVLDILKTLEHESTSKRCLAERSFLRE
LEGGCQVPIGVRTEINNNELILEGMVASLDGKRLIRDIKKGSVSSAEEIGIDLANELKGR
GAGEILEEIFKSARA
>Q8ZYW7|hydroxymethylbilane synthase|EC 2.5.1.61|Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)|Swiss-Prot
MRLKVATRGSRLSLLQTEEFLAQIKAVEPRVDFEIKIVKTTGDLVQDKPLFQIGVKGIFE
KEVNLAVLKGEADIAIHSLKDLPSEISPGLVLAGFSKRTLPYDAVVSAVGYDLESLPKGA
LVGTSSVRRAEFIKSLRPDVRIEPLRGNVDTRVQKILQGKYDAAVMAAAGILRLYGESPP
VKLSLLRPELLPPPPGQGIVAAVVREGEGWLIDLLKKASDPRATVEALAEREFLKNVGAG
CHVAVGGTAFSRNGYIEFIAGYAASGKRFVVKLFGEDPVEVGRRAAEEIKRVAASVR
>C0Q3B3|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella paratyphi C (strain RKS4594)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>Q2YTB9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain bovine RF122 / ET3-1)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDIDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>Q7U5C2|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain WH8102)|Swiss-Prot
MALTELRIASRRSQLAMVQTNWVKAELEKAHPGLTITVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGRAEIAVHSLKDLPTNLPEGLMLGCITEREDPADALVVNAKNANHKLD
TLPEGAVVGTSSLRRLAQLRHHYPHLSFKDVRGNVITRLEKLDSGDYDCLILAAAGLERL
GFGNRIHQIIPGDISLHAVGQGALGIECVEDKPEVLEIIKVLEHTTTSRRCLAERAFLRE
LEGGCQVPIGVNSQINNEELTLTGMVASLDGKRLIRDEASGSAADPESIGIELAGKLKHQ
GAGAILKEIFDEVRPEA
>Q3BXV3|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas campestris pv. vesicatoria (strain 85-10)|Swiss-Prot
MTTLRIATRKSPLALWQSEHVAAALRQHHPGLEVVLVPMSTRGDEMLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDAPFVLPAILERGDPADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEAR
ISARLDAPEWLPAPAQGAVAVECRGDDARIYSLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAAFARWEGQGLFLQGMVGSASDGRLIHADAHGSAEDTEALGRRVAQGLFDKGAAQL
LAEL
>A8ERI4|hydroxymethylbilane synthase|EC 2.5.1.61|Arcobacter butzleri (strain RM4018)|Swiss-Prot
MEKLVIATRRSQLALWQSEYVKSRLLEHYPNMQIELQEFVTKGDKILDVPLAKIGGKGLF
TKELEVAMLEGSAHLAVHSLKDVPTQFEDGLMLAAVTKRFDPRDAFLSNKYTSLEELPKG
AIVGTTSLRRRMALKILRPDIELKDLRGNINTRIAKLNAGEYDAIILAATGIQKLGIENE
VKYFSPISTDIMIPSMGQATLGIETTNDPKVLEILKVLNDNNAHIESTVERSFVDTLQGG
CQVPIGVKATILDENSIRVQAIVGMPDGSEYISEDITADIEDYETIGQNLAQIFIDQGAK
ELLEKAEKVAFK
>A9IKF3|hydroxymethylbilane synthase|EC 2.5.1.61|Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)|Swiss-Prot
MSVPQRLVIATRASRLALWQAEHVRDRLRALYPACAVELLTLTTRGDQILDRTLSKVGGK
GLFVKELETALLDGRADLAVHSLKDVPVDLQAPFELCAILERADPRDAFVSNQYTTLADL
PAGAVVGTSSLRRESQIRQRYPHLSVKPLRGNLDTRLSKLDRGDYAAIVLAAAGLQRLGM
GERIRSLLEPEDSLPAAGQGALGIEIRNDRNDLREWLAPLACSRTTACVVAERAVSRALG
GSCQVPLAAYAELNGNSLALRALVASPDGTRVIRSQHAGPAEQAQAIGQAAAQELLSNGA
DAILAELQDPPAS
>A4JGV4|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia vietnamiensis (strain G4 / LMG 22486)|Swiss-Prot
MNSETFSAGPKSAPAPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQ
ILDRTLSKVGGKGLFVKELENALADGRADLAVHSLKDVPMALPDGFALAAIMAREDARDA
FVSNDYASLDALPAGAVVGTSSLRREAMLRARYPHLNVLPLRGNLDTRLAKLDRGDYAAI
ILAAAGLKRLGLEARIRALIDVEDSLPAAGQGALGIEIAAHRSDVAQWLAPLHDPHTALA
VEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGRRVLSAQACGAVMTAADAL
ALGRAVSDELDAQGARDIVNALLAGSQVGKGDA
>Q97MU4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)|Swiss-Prot
MKLTIATRKSKLAQVQTELIINVLKDKYGISSEKLLMETLGDKILDKSLADIGGKGLFIK
DIERILLEDKADAAVHSMKDVPFEVPDMFEIAAVTLRVDVRDVFVSRDGTHFKDLKNGAV
IGTSSNRRAAQLKMLRDDIKVVPIRGNVQTRIRKMGEEKLDGIILAAAGLKRLNMENIIT
DYFSVEEMIPAVGQGALGVEIKKENKNRDLFRKLDNKNSRMCVEAERSFMRTLNGDCHST
IGAYAEIVNGQMNVLGFYEIDGRRVKKDVSGNIEDYMSLGKTLAEKILEDK
>Q83A37|hydroxymethylbilane synthase|EC 2.5.1.61|Coxiella burnetii (strain RSA 493 / Nine Mile phase I)|Swiss-Prot
MIKKRSILIVTRKSPLALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGK
DLFVKDLQKALLNRDADIAVHSIKDMSACDGPELMVGAFIRREDPRDVLIVKGELSTLPP
HAVIGTSSPRRQCQLKKFQPGCKIKEIRGNVGTRLAKLDAGHYEAIVLAAAGLKRLGLEN
RIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAERAVNEKLGGD
CFTPIAAHAIIKNDQLSLFAMLGKIDGRVIIRATEIGNSEEAKRIGFKVASQLLEQGGDS
LLRELKQ
>B7NFA7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C5D5K7|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus sp. (strain WCH70)|Swiss-Prot
MRKIIVGSRRSKLALTQTNWVIERLRQLGAPFEFEVKEIVTKGDKIIDVTLSKVGGKGLF
VKEIEHAMLNGEIDMAVHSMKDMPAVLPDGLIIGCVPPREDHHDVLISKNKETFANLPSG
AIVGTSSLRRSAQILAKRPDLKIKWIRGNIDTRLAKLQNEDYDAIILAAAGLVRMGWARD
VITEYLSTDVCLPAVGQGALAVECRENDEELREWLQKLNDVHTERAVLAERVFLQQMEGG
CQVPIAGYAYIDDREDIVLTALVASPDGKEIYKETVSGSNPEEVGTNAAKMLIERGAKAL
IDRIKEEMNRQ
>Q1MPL2|hydroxymethylbilane synthase|EC 2.5.1.61|Lawsonia intracellularis (strain PHE/MN1-00)|Swiss-Prot
MKKITIATRGSKLAFWQANYIKDQLQKMYSYLEVDLMVIKTKGDHILDVPLAKVGGKGLF
VKEIEEALLSGEADCAVHSMKDVPMELPFELCLAAITEREDPTDMFLSIKYSGVKSLPEN
ALVGTSSLRRQAQLLALRPDLQIIPLRGNIDTRLRKLMAEEFDAIIMATAGIKRLGLIAP
YMSSLPCSVMLPAVGQGALGIEVQKERQDVLELFSFLNHKETYHCIQAERDFLAGLDGGC
QVPIAGYATICKQETICLEGLVAKSDGSVMIRNRLERSVSDAYDIGMTLSKILLAEGADD
ILASMHTIL
>P64337|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)|Swiss-Prot
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>Q9CK24|hydroxymethylbilane synthase|EC 2.5.1.61|Pasteurella multocida (strain Pm70)|Swiss-Prot
MMTRKSLRIATRQSPLALWQANYVKACLEKIHAGLVVELVPMVTKGDVILDTPLAKIGGK
GLFVKELEQALLKGEADIAVHSMKDVPMQFPAGLMLSTICQREDPRDAFVSNSYRTLMEL
PAGAVVGTSSLRRQCQLKQLRPDLHIHSLRGNVGTRLAKLDNGDYDAIILAAAGLIRLGQ
QQRITSLIDVTQCLPAVGQGAVGIECRQEAEIELLLAPLADPETTACVLAERAMNRHLQG
GCQVPIAGYAIIEEGQLFLRALVGEVDGSSILRAEGRSAVADAETLGIQVAEKLLQQGAD
KILQTLYSN
>B7V5F0|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa (strain LESB58)|Swiss-Prot
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAE
AILEAVYGEAGHP
>Q4ULA5|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)|Swiss-Prot
MTNSIRIGTRKSPLALIQTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEELVIAAILEREDPRDVFVCLNYKSIEELPQ
NAVIGSSAVRRKAFIQKIRSDLKVTVFRGNIDSRIKKLMTAEVDATILAYAGLKRLRAFN
PEYCHLIEYSQMLPCIGQGVIAVEIRQDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSKYLDADNIQTDFMLGNLDCSKIIFHTEVTDINTSKEAGIKAAKMMLNQLD
K
>A0KS60|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella sp. (strain ANA-3)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERVHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELP
LGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEG
GCQVPIGAFAEIHGDEMTLRGLVGNPDGSEIIEGVITGPKTEATKLGVALAEELLSKGAK
SILDAVYAKA
>A3CL78|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis (strain SK36)|Swiss-Prot
MKVIKVGTRKSKLAMTQTQQLVDQLKALHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEINMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPK
GSLIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELLSLLAAVQDEKTAAEVAVERAVLAQM
NADCTFPIAAFAQKNGQGYQLEAMLAKEDGQCIFVSLQGQDGQQLAEQAVRQLADKGAVG
MPWLKK
>B8GSU8|hydroxymethylbilane synthase|EC 2.5.1.61|Thioalkalivibrio sp. (strain HL-EbGR7)|Swiss-Prot
MPLDTLRIATRKSPLAVWQAEHVAALVKARHPGVRVELVGMTTQGDRILDTPLAKVGGKG
LFVKELETGLLEGRADIAVHSMKDVPMELPEGLCLPVILDREDPRDAFVSNTFKSLDELP
RDARVGTSSLRRQCQLRHDHPHFQILDLRGNVNTRLAKLDAGEFDAIILAAAGLKRLGFE
VRIASEITPEQSLPAIGQGAIGIECRENDPEVMALIGSLDDPDTHVRVAAERAMNARLNG
GCQVPIAGYAELTDADTLRLRGLVGEPDGSLILRAELSGPRAEAEALGRAVADLLLHEGA
GPILAELGLGPDADRS
>Q1CBN1|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis bv. Antiqua (strain Antiqua)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>C3P9E9|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus anthracis (strain A0248)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>B2S842|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella abortus (strain S19)|Swiss-Prot
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDVLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>A7GYU4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter curvus (strain 525.92)|Swiss-Prot
MKILKIATRKSALALWQSEHIKARLMAQHAGLQVELVGMKTKGDVILDTPLAKIGGKGLF
TKELEDSMLSGQTHIAVHSLKDVPVAFLDGLVLAAICSREDVRDAMISQRYVKFDDLPQS
AKVGTTSLRRKMQLLRMRPDLNIISLRGNVQTRLRKLKEGEFDAIILAMAGINRLNLADE
VAHIYPFDIAQMTPAMGQGALGVEAVDDAQILEKIKFLNDERSVIETRVERDFVTLLEGG
CQVPIGINARLASEEIEINAIVGLPDGSEVITENLTAKKSEFESVGKELAREFIARGAKE
LLKRAEEMANL
>B2UXC4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain Alaska E43 / Type E3)|Swiss-Prot
MNELIIATRKSKLAQVQTEIIMSELKSKFNIDSKKLLIVTEGDRKLDVSLNKIGGKGLFV
KDIELALLNKEAHAAVHSMKDVPFEVSSEFEITAITGREDIRDVFISNGDISFKDIKKGA
KVGTSSIRRAAQLKLLRSDLEIVPIRGNVQTRLKKMEEQNLDGIVLAAAGLKRLGDENLI
TDYFDPKEFLPAVSQGALGIECLKDGDANKYFEALIDAEATLTVEAERSFMKELQGDCHS
LIGAYSEIQGDDLYMIGIYDIGGKIVKKDILGCKTNNIELGKKLAQKILG
>Q479S8|hydroxymethylbilane synthase|EC 2.5.1.61|Dechloromonas aromatica (strain RCB)|Swiss-Prot
MSRPSKIVIASRESRLAMWQAVHVRDRLSSLNPGAEVVILGMTTKGDQILDRPLAEIGGK
GLFIKELEVAMQEGKAHLAVHSMKDVPMVMPEGFVLAAISARENPRDAFVSNKYNGLDDL
PAGAIVGTSSLRRESILRAKYPQLVIKSLRGNLDTRLKKLDAGEYDAIILAAAGLIRLGM
ENRIKSVLTAEQSLPAPGQGALGIELIDGAADMADVVAPLNDPETAHCVKAERAFSRALG
GSCQVPLGGYAIIDNGQLWLRGFVATADGQEVVSAELRGNPADDEALGLQLAAELRAKGA
DAILEKLAHCK
>A4WG12|hydroxymethylbilane synthase|EC 2.5.1.61|Enterobacter sp. (strain 638)|Swiss-Prot
MLDNVLRIATRQSPLALWQAQYVKQRLEACHQGLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLENRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNRYASLDDLP
KGSVVGTSSLRRQCQLAERRPDLVIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRVAMPPELCLPAVGQGAVGIECRLDDDRTRALLSPLNHDETAIRVQAERAMNMRLEG
GCQVPIGSYAELINGELWLRALVGAPDGSQMVRGERRGLPQDAEMLGISLADELLNNGAR
AILADVYNGEPPA
>Q0I178|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus somnus (strain 129Pt)|Swiss-Prot
MSINKTLKIATRQSPLALWQANYVKNRLQQRYSHLSVELVPIITKGDVILDTPLAKIGGK
GLFVKELENALLNGEADIAVHSMKDVPMQFPKGLELSVICPREDPRDAFVSNKYRTLDEL
PQGAIVGTSSLRRQCQLKNWRADLDIRSLRGNVGTRLNKLDQGDYDAIILASAGLIRLGL
TERIRSFIEIDTILPACGQGAVGIECRVDDRDVQSLLMPLADQTTTYCVLAERAMNFHLQ
GGCQVPIGAYAILENNQLYLRGLVGDVHGSQILSAEGQFELSLDFESSQSAVQKAEELGV
SIAEQLLQQGADKILQAVYQS
>Q6AHF1|hydroxymethylbilane synthase|EC 2.5.1.61|Leifsonia xyli subsp. xyli (strain CTCB07)|Swiss-Prot
MIVSDGPAERRQGALRVGTRGSPLAVAQTQAVSAAVARATGFDIELVTVTTHGDTSRESL
SELGGTGVFATALRDALRNGECDLVVHSLKDLPTAPAPGLVLGAVPKRADARDTLCARDG
LRFGELPEGASVGTGSPRRAAQLRAQRPGLDIVDIRGNVDTRLSRVSAGDLDAVVLAAAG
LGRLGRLDAATDFFSLSTMPTAPGQGALALEVREGDERGRGPIARALAAVDHATTCAATT
AERAVLAGLEAGCAAPVGATAMIDDGLLFLTATVYRPDGAAQLTASHAATPDSFGAAHLD
EAARDVGERVVAELLASGAADLAPLKGLR
>Q49808|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium leprae (strain TN)|Swiss-Prot
MIRIGTRGSLLATTQAALVRDALIANGHPAELVIVNTAGDQSSASIDSLGVGVFTTALRA
AIEEGCVDAAVHSYKDLPTADDPRFTVAAIPPRNDPRDAVVTRDELVLAELPAGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDEVTETLD
PVQMVPAPAQGAIAVECRAGDSRLVAVLAALDDADTRAAVTAERVLLAELEAGCSAPVGA
IAQVVESIDGEGRVFEELSLRGCVAALDGSDVIRASGISTSGRASELGLAVAVELFELGA
RELMWGARSDRARGS
>Q3B2Z5|hydroxymethylbilane synthase|EC 2.5.1.61|Pelodictyon luteolum (strain DSM 273)|Swiss-Prot
MKKQLIIGTRSSPLALWQAEFTKAELSRHFPDLEITLKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKFLIAKEIDLAVHSLKDVPTATPEGLIISAFTEREDTRDVIISKTGAKLLDLPK
NAKVATSSLRRMSQLKSLRPDFEICDIRGNLNTRFKKFDEGEFDAMMLAYAGVYRLNFSD
RISEILPHEIMLPAVGQGALGIETRVDDEQTREIVKVMNHSTTEYCCKAERALLRHLQGG
CQIPIGAYASFKNGTLHLLAFVGSTDGTIGIRDEITKTGLTSPSQAEEAGIELAKELLKQ
GAEKILSEIRKSC
>Q4K3X3|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)|Swiss-Prot
MSSREIRIATRKSALALWQAEYVKARLQEAHPGLVVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENQADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTYASLDELP
EGSVVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRISSSISVDDSLPAGGQGAVGIECRSADIEIHALLAPLHHADTASRVTAERALNKHLNG
GCQVPIACYAVLEGEQIWLRGLVGEPSGGLLLSAEARGPRASAAELGVQVADALLAQGAD
DILRAVYGEAGEE
>B0BY00|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia rickettsii (strain Iowa)|Swiss-Prot
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>A1RPD7|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella sp. (strain W3-18-1)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAILEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNIYKTISELP
LGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
GRIASFISAEQSLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEG
GCQVPIGAFAEINGDEMTLRGLVGNPDGSEIIEGIITGPKTEATQLGVALAEELLSKGAK
SILDAVYAKA
>C3MJ21|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)|Swiss-Prot
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIIDIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLERDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNEDIIP
>Q5E8T5|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio fischeri (strain ATCC 700601 / ES114)|Swiss-Prot
MSQQLPVRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQLKEARPDLIIKELRGNVGTRLQKLDDGNYDAIILACAGLIRLGL
EDRIKSAIEPEQSLPAVGQGAVGIEARLDDDRLRALLEPLNHPETANRVLCERAMNNRLE
GGCQVPIGSYSLIDGDQIWLRALVGEPDGSVMIRGEVSGPVSDAEALGTQLADQLLNDGA
KEILERLYAEA
>Q1CNI3|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis bv. Antiqua (strain Nepal516)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>A8MGE4|hydroxymethylbilane synthase|EC 2.5.1.61|Alkaliphilus oremlandii (strain OhILAs)|Swiss-Prot
MKIRVGSRESKLAVKQSEIVIEAIRKYDPNIEIELVTMKTTGDIKLDQTLDKIGGKGLFI
KELDQALYDDRVDITVHSFKDMPMAIDEYLPIVAVSKREDPRDVLVLPKTVKEPDFSKPI
GCSSFRRKIQLQEIYPHCSVEPIRGNVLTRLEKLDRGEFSAITLALAGLKRLGLEERISR
IFEVTEILPAACQGVIVVQARKGFDVSFLSDFHDKEAWDISMAERSFVRTLNGGCSSPVA
AYGEIKDNYLTLTGLYVDSSNSVHKKTITGARKQGEEMGFNLALQMKGEDEVHGKD
>Q491Z6|hydroxymethylbilane synthase|EC 2.5.1.61|Blochmannia pennsylvanicus (strain BPEN)|Swiss-Prot
MKNKILKIATRKSQLAICQAQYVHNELKHYHPTLSIELMPIVTTGDKFLNIDAKNKIKKG
AFIKELEHALINFRADIAVHSMKDITVPLPDELTLPVLCKRNDPRDAFVSLKYPNIDTLP
IGSVIGTSSLRRQCQIRAHRPDLVVSNLRGNIDTRLKKLQYGQYDAIVLAVAGLQRLQLH
EYIRVHIDPSDLLPAMGQGVIAIECRSNDADILSLLSPLYHQETSFRVRAERAVTTYLES
YCHLPIASYAEIEEDQIWLRALIGLPDGSKIIRTEGRAPLDQAEKLGFILAEDLLIKFKR
>B2T1D1|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia phytofirmans (strain DSM 17436 / PsJN)|Swiss-Prot
MNTETFSTPPHTLVIASRESRLAMWQAEHVRCALHKLYPSCDVKILGMTTRGDQILDRTL
SKVGGKGLFVKELEAALADGRADLAVHSLKDVPMELPAGFALSTIMEREDPRDALVSNDY
DSLAALPAGAVVGTSSLRREAMLRMRYPHLEVRPLRGNLDTRLSKLDRGDYAAIILAAAG
LKRLGLGERIRALLDPEDSLPAAGQGALGIEIRADRADLAAWLAPLHHDHTAAAVEAERM
VSRALGGSCEVPLAAYATWRDGALHLRGIVATPDGQRVLSAQASAPAPSVERAVALGQEV
ASALEQQGAMDIVRALSAASGPAAAKQGAAEDGAADSAATGE
>Q8KCJ4|hydroxymethylbilane synthase|EC 2.5.1.61|Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)|Swiss-Prot
MKKELIIGTRSSPLALWQAEFTKAELSRHFPELNITLKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKHLLAKEIDLAVHSLKDVPTGTPEGLVISSFTKREDTRDVIISKSGKGLKDLPP
NARMATSSLRRMSQLLSMRPDLQILDIRGNLNTRFKKFDDGEFDAMMLAYAGVYRLEFSD
RISEILPHDVMLPAVGQGALGIETRTDDAETIEIVRVMNDSNTEICCRAERALLRHLQGG
CQIPIGCYGSYISGTLKLLAFVGSVDGKTALRNELTKPVNTPEEAEAVGIELAEVLLSMG
AEKILADIRKTR
>B6J3T6|hydroxymethylbilane synthase|EC 2.5.1.61|Coxiella burnetii (strain CbuG_Q212)|Swiss-Prot
MIKKRSILIVTRKSPLALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGK
DLFVKDLQKALLNRDADIAVHSIKDMSACDGPELMVGAFIRREDPRDVLIVKGELSTLPP
HAVIGTSSPRRQCQLKKFQPGCKIKEIRGNVGTRLAKLDAGHYEAIVLAAAGLKRLGLEN
RIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAERAVNEKLGGD
CFTPIAAHAIIKNDQLSLFAMLGKIDGRVIIRATEIGNSEEAKRIGFKVASQLLEQGGDS
LLRELKQ
>B1XAH2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain K12 / DH10B)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B9M416|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter sp. (strain FRC-32)|Swiss-Prot
MALKQLRIGTRASQLALWQANWVKSELEQRYPGMEVSLVKIKTIGDKILDVPLAQVGGKG
LFVKEIEEAMLRGDIDIAVHSMKDVPTEFPEGLGLHCITEREDPRDAVISRGTKFADLPQ
GAKIGTSALRRQAQLLKVRPDMEMVIIRGNVETRINKLETEKLDAVILAAAGLKRLGFTE
KVAEYLPTDLSIPAIGQGALGIECRLDNEEVKQTIDFFNHPATAYAVRAERALLWRCEGG
CQVPIAAFGEVTGSDLKLVGFIASVDGKTSVRGTITGPAADCEKLGIKLAEQLLADGGHA
ILAEVYQREVSREKEIPV
>A5VM67|hydroxymethylbilane synthase|EC 2.5.1.61|Lactobacillus reuteri (strain DSM 20016)|Swiss-Prot
MTNKVIVGSRKSKLAMAQTELVIASLEKIFPDIKFEIKNVITEGDRNRHVSLAKIGGKGV
FVKEIEDELKDGTIDFAVHSLKDVMPILPEELVLGAFPKRVSPYDCLVSRKNLSSLNDLP
KGARIGTNSLRRQGQLLSIRPDLKIIPIRGNIDTRLRKIDTEALDGIILAEAGLTRLNID
LSSYHVLDLQNYIMPAVGQGCLAIECRKNDTRIRKMLDQINDEESAYCVQVEREFMRELG
GSCNFPIGGHAYAKNGQILFDGLIASPNGEHVIKETKIPANNSGVGKKVADQLLAKDKFG
IIEGE
>P22907|hydroxymethylbilane synthase|EC 2.5.1.61|Mus musculus|Swiss-Prot
MSGNGGAATTAEENGSKMRVIRVGTRKSQLARIQTDTVVAMLKALYPGIQFEIIAMSTTG
DKILDTALSKIGEKSLFTKELENALEKNEVDLVVHSLKDVPTILPPGFTIGAICKRENPC
DAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDEL
QEFSAIVLAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVSVLHD
PETLLRCIAERAFLRHLEGGCSVPVAVHTVMKDGQLYLTGGVWSLDGSDSMQETMQATIQ
VPVQQEDGPEDDPQLVGITARNIPRGAQLAAENLGISLASLLLNKGAKNILDVARQLNDV
R
>Q6H6D2|hydroxymethylbilane synthase|EC 2.5.1.61|Oryza sativa subsp. japonica|Swiss-Prot
MPPPPRCAATTAHHSLLGSPTCLARPRRRCCPVRAAVAVQAEAQAKVSLIRIGTRGSPLA
LAQAHETRDKLKAAHSELAEEGAVEIVIIKTTGDMILDKPLADIGGKGLFTKEIDDALLQ
GRIDIAVHSMKDVPTYLPEGTILPCNLPREDVRDAFICLTASSLAELPAGSVVGSASLRR
QSQILYKYPSLKVVNFRGNVQTRLRKLKEGDVHATLLALAGLKRLNMAETATSVLSVDEM
LPAVAQGAIGIACRSSDDTMMNYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIAAYASR
DKDGNCSFRGLLASPDGSTVYETSRTGPYDFDIMVEMGKDAGHELKAKAGPGFFDSLQ
>A4SFJ8|hydroxymethylbilane synthase|EC 2.5.1.61|Prosthecochloris vibrioformis (strain DSM 265)|Swiss-Prot
MKKQLIIGTRSSPLALWQAEYTKAELSRHFPDLDITLKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKFLIAKEIDLAVHSLKDVPTATPEGLIISAFTEREDTRDVIISKNGVKMLDLPK
NAKVATSSLRRMSQLKSLRPDFDIKDIRGNLNTRFQKFDEGEFDAMMLAYAGVYRLNFSD
RISEILPHEIMLPAVGQGALGIETRVDDEQTREIVKVMNHSNTEYCCKAERSLLRHLQGG
CQIPIGSYASFKNGTLHLLAFVGSVDGTKGIRNEITKTGLTSPAQAEAAGIELAEELLKQ
GAEEILSEIRKTC
>Q1RJN7|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia bellii (strain RML369-C)|Swiss-Prot
MINSIRIGTRKSKLALTQTNLVIEQIKQHFPNINCEIVEITTSGDLIQNKPLYDIGGKAL
FLKEIEQALLNKKVDLAVHSLKDVPGIIPKDLSIEAVLEREDSRDVFVCLTHKSIEELPK
NAVIGTSSVRRKLCVQRMRPDLEIIVFRGNVDSRINKLINKEVDATILAYAGLKRLNAFN
PEYCHLIEHSQMLPCIGQGVIAIEIRKDDHDMIEICKQINHLPTFELIKPERALLEYLDA
NCRTPIGAYSKYLDNGDIQTDFMLGNLDGSKIAFHTEISNPKTSKESGIKAAKVMLLSLS
>Q8E9H0|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella oneidensis (strain MR-1)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNIYKSISELP
LGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEG
GCQVPIGAFAEIDGDEMTLRGLVGNPDGSEIIEGVITGPKTEATQLGVALAEELLSKGAK
SILDAVYAKA
>Q49YA2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)|Swiss-Prot
MRKLVVGSRRSKLALTQSRQFIDKLKAIDPSLEIEIKEIVTKGDLIVDKQLSKVGGKGLF
VKEIQNELFNHGIDMAIHSLKDVPSVIPDGLTLGCIPDRENPYDAYIAKNHVPLNELPDN
SIVGTSSLRRGAQILAKYPKLQIKWIRGNIDTRLNKLETEDYDAIILAAAGLKRMGWSDD
IVTSYLDKETLIPAIGQGALGIECRSDDETLLSLLSKVHNQDVADCVTAERTFLTRMNGS
CQVPIGGYATKEADGTIEFTGLIMSPDGKERYQHTVRGTDPVALGEEVTKVLNEQGAYEI
IKALNEEQ
>Q97B26|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)|Swiss-Prot
MKIKIGTRPSNLAVAQANMVASSLEAIGIDTEIVKHRSAGDIDTKNPIYSIGKTGVFVQD
LNNMILRGEIDVAVHSAKDIPSEIENRLTIAATLKRGSFNDALVSKYDLRSLPISAKVGT
SSIRRIFQLKYARQDLKFENIRGNIETRIAKMSELGLDAIVMAEAAIQRLGLNVEYSKLD
ENKFVPAPNQGIIAVVSKKEGTVRKILEEINDENTFEEMQIERSVVQQLKLGCSTPVGIL
SRPSGKGHKIIAQFFSMQGDDVSVFEQYLNDLSDVDSLVSYIRENIPREYGYIASEE
>A1JI86|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPIAFPEGLGLVTICERDDPRDAFVSINYAHLDELP
AGSIVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDKGEYHAIILAVAGLKRLGLE
TRIRYAMPAEESLPAVGQGAVGIECRLDDNFTRQLLAPLNHRETELRVCAERAMNTRLEG
GCQVPIGSYAELDGDTLWLRALVGAPDGSEIIRGERRGPAENAEQMGVELADELLSRGAR
EILAEVYQDNPPL
>Q0A577|hydroxymethylbilane synthase|EC 2.5.1.61|Alkalilimnicola ehrlichei (strain MLHE-1)|Swiss-Prot
MPQDKLRIATRRSPLAMWQAEHVAAELRRHHPGLEVELVPMVTRGDRILDQALSRIGGKG
LFIKELEQGMEEGRADLAVHSMKDVPWRMPDGFALPVILERHEPTDAFVSNHYRRLDDLP
EGGHLGTASLRRQCQAKARRPDLRVSTLRGNVNTRLAKLDAGEFDAIILAASGLSRLGFD
ERIARRLPPEESLPAVGQGALGIECLAEDRRVQELVAPLDHGPTHTLLKAERAMNARLQG
SCQVPIAGYACYQGEEIWLRGLVGSPDGQEIVRGEVRGPIAQAAELGDRLGGELLERGAA
RILADLAD
>A9VIT8|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus weihenstephanensis (strain KBAB4)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPDGLTIGCTPKRVDPRDAFISKNGESFKDLAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKDEDYDAIILATAGLQRMGWDGE
VITEHLDETLCVPAVGQGALAIECREDDTDLLQLLAHINDAVTERTVAAERVFLHKLEGG
CQVPIAGYATLKENDAIELTALVGSMDGSVLLKEIVVGIDPKQVGLEAADRLIKQGAKEL
ILAANKEQQ
>Q3JUW3|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei (strain 1710b)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>A1BHD6|hydroxymethylbilane synthase|EC 2.5.1.61|Chlorobium phaeobacteroides (strain DSM 266)|Swiss-Prot
MKKQLIIGTRSSPLALWQAEFTKAELSRHYPELDITLKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKHLIAKEIDLAVHSLKDVPTSTPEGLIITSFTEREDTRDVIISRSGETLLNLPQ
NARIATSSLRRMSQLLSMRPDFEICDIRGNLNTRFKKFDEGEFDAMMLAYAGVFRLKFSD
RISEILPHDVMLPAVGQGALGIETRVDDEQTREIVRILNHSNTEYCCRAERALLRHLQGG
CQIPIGAYASFKNGTLKLLAFVGSVNGKIGLRNEITKTGLVSPEQAEEAGIELAKELLKQ
GADEILSEIRKTR
>A4QB59|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glutamicum (strain R)|Swiss-Prot
MTLKIGTRGSKLATTQAGTIRDQLKYFGRDAELHIVTTPGDVNMSPVERIGVGVFTQALR
DVLHAGECDVAVHSMKDLPTAADPRFHLVVPTRADSREALIARDGLTLAELPEGAKVGTS
APRRISQLKAIRPDLEILPLRGNIDTRMGKVTSGELDAVMLAYAGLTRVGMQDRATEVFD
ADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAERTVLNRLEAGCTAPVAA
HATLDGYSGDTMTLTAGVYALDGSDQLVFSAEGDGARPEELGELVAQQLIDAGAANLLGD
RS
>B7N295|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O81 (strain ED1a)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q5KWK6|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus kaustophilus (strain HTA426)|Swiss-Prot
MRNIVVGSRRSKLALTQTKWVINELKQLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLF
VKEIEHELLAGGIDMAVHSMKDMPAVLPEGLVIGAVSRREDARDVLVSKGNRMLSDLPPG
SVIGTSSLRRSAQLLAYRPDLTIKWIRGNIDTRLAKLESEEYDAIVLAAAGLARMGWGDD
VISDYLPFDVCVPAVGQGALAVECREDDDELRQWLSRLNDEQTERAVRAERAFLQQMEGG
CQVPIAGYAEVKEGTVRLTALVASPDGKEMYKEIVTGADPEAVGRQAAAILSEQGAKALI
ERVKKELGD
>A6TGI8|hydroxymethylbilane synthase|EC 2.5.1.61|Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)|Swiss-Prot
MLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLKVELVPMVTRGDVILDTPLAKVGGKG
LFVKELELAMLEGRADIAVHSMKDVPVEFPEGLGLVTICERDDPRDAFVSNRYASIDELP
AGSVVGTSSLRRQCQLAATRPDLAIRSLRGNVGTRLSKLDNGEYDAIILAAAGLKRLQLE
ARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTRGLLAPLNHTETAVRVRAERAMNTRLEG
GCQVPIGSYAELKDGELWLRALVGAPDGSQLVRGERRGPAEQAEALGISLAEELLDNGAR
EILAAVYDGEAPR
>O26960|hydroxymethylbilane synthase|EC 2.5.1.61|Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)|Swiss-Prot
MIAGTRGSRLALVQTNHVIEMLSEVCKEKIEKKIIKTKGDRIRDSQLYSMDSRGLFTREL
DMAVLNEEVDLAVHSLKDVPSDLDPDLAIAAVPPRESPAEVLVSRLDWEDLPQGSKLGTS
SLRREAFCNHHQKNFKMEPLRGNIDTRIRKVMDGEVHATIMAEAGLKRLGLEEHIKRRFP
VEYFTPAAGQGALAVITRADSELISSIGRITHHPSLQEVTAEKTLLRELGAGCQCPLGVI
GRATGNQLTLYAVLLTREGEMLRKVTVRGPLAEAEDIGKKAAKEMEDYI
>A6WXJ2|hydroxymethylbilane synthase|EC 2.5.1.61|Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)|Swiss-Prot
MQTASLKNGTLKIGTRGSKLALAQAYETRRRLMEAHGLPEEAIEIIPMSTAGDRIQDRAL
SEIGGKGLFTEEIEQALTDGRIDLAVHSTKDMPTVLPDGLHLSVFLEREDPRDAFIGRTA
SRLLDLPQGATVGSSSLRRQALIRRLRPDIQVVIFRGNVDTRLRKLEAGEVDGTFLACAG
LRRLGLGDVITDLADPESFPPAPGQGAIGIETRIGDTRIDTLLAPLAHRETGIALACERA
FLAALDGSCRTPIAGLATVNGDTVSFHGMILKPDGSEAHEIKTEGPASNAAAIGTEAAEH
LRAKAGPQFFEGWE
>Q7V2I1|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4)|Swiss-Prot
MTKFKLKIASRRSKLAMVQTLWVKEQLEKNIPDLEVSIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGHADIAVHSLKDLPTNLPDGLTLGCITKREDPSDALVVNKKNKIYQLE
SLPPGSIVGTSSLRRLAQLRYKFPHLDFKDIRGNVITRIEKLDSGEFDCIILAAAGLKRL
GFESRVHQIIPNEISLHAVGQGALGIECKSDDKEVLKIISVLEDKVSSQRCLAERSFLRE
LEGGCQVPIGVNSSIQNDEIALIGMVASIDGKRLIKNESIGNIKYPEEVGKKLAEKLKLQ
GADKILSEIFEQFRDK
>C3PNS9|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia africae (strain ESF-5)|Swiss-Prot
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDVSTGLTYKLPLEV
EFGKVSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>A9L5G0|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella baltica (strain OS195)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLDDLADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELP
LGATVGTSSLRRQCQIRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRINDERVKALLAPLEHLETRYRVLAERAMNTRLEG
GCQVPIGAFAEIDGDEMTLRGLVGNPDGSEIIEGVITGPKTDATQLGVALAEELLSKGAK
SILDAVYAKA
>Q5HNN3|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis (strain ATCC 35984 / RP62A)|Swiss-Prot
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>B1YDP0|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoproteus neutrophilus (strain DSM 2338 / JCM 9278 / V24Sta)|Swiss-Prot
MKIRVATRGSKLSLIQTEELLAQIKAVEPDIRFEIVVVKTTGDLIQDKPLFQIGVKGVFE
KEVNLAVLRGEADMAVHSLKDLPSDLTPGLALAGYSRRAPPNDALVSPRGYTLETLPRGA
VVGTSSVRRAEFLKAARPDLEIKPLRGNVDTRVAKILSGQYDAAVMAAAGLQRLYGGAPP
IPAVPLAVEDLPPPPGQGIVAAVAREEDTWLTDLLRRASDRKAAAEAAAERAFLAEVGAG
CHVAVGGIARQTPAGIEFTAGYAQGGRKHLVKVYGEDPTEVGRRAARLVAQAMKKT
>Q87CC9|hydroxymethylbilane synthase|EC 2.5.1.61|Xylella fastidiosa (strain Temecula1 / ATCC 700964)|Swiss-Prot
MPLLRIATRKSLLAMWQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIG
ARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQR
MTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRKCVIAERTMNRALHGSC
HVPVGAYASYEVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAEL
LAATA
>Q0VM28|hydroxymethylbilane synthase|EC 2.5.1.61|Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)|Swiss-Prot
MSREILRIATRSSPLAIWQAEYVQQRLESLHEGLRVELVRIKTQGDKILDTPLAKIGGKG
LFVKELEEAMMDGRADIAVHSMKDVPMELPPGFALPVICEREDPRDAFVSNTFDGLSSLP
HGACVGTSSLRRQAQVKANRPDLVVNSLRGNVQTRLGKLDAGNFDAIILAAAGLKRLEMH
DRIRYEMPPEESLPAVGQGAVGIECREGDESTIELLSPLSDVDTWDRVVAERAMNRRLEG
GCQVPIAGFALLEDGQLWLRGLVAEEDGSRVLRAEGTAPRGQGAELGIDIAEQLLAQGAD
EILKALYARQ
>P16616|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus subtilis (strain 168)|Swiss-Prot
MMRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGL
FVKEIEQALLNEEIDMAVHSMKDMPAVLPEGLVIGCIPEREDPRDALISKNRVKLSEMKK
GAVIGTSSLRRSAQLLIERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKQ
DVVTEFLEPERCLPAVGQGALAIECRESDEELLALFSQFTDEYTKRTVLAERAFLNAMEG
GCQVPIAGYSVLNGQDEIEMTGLVASPDGKIIFKETVTGNDPEEVGKRCAALMADKGAKD
LIDRVKRELDEDGK
>A3NSN6|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei (strain 1106a)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>B3EPK0|hydroxymethylbilane synthase|EC 2.5.1.61|Chlorobium phaeobacteroides (strain BS1)|Swiss-Prot
MKKKLIIGTRSSPLALWQADFTQAELSKHFPDLEIELKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKHLISGEIDLAVHSLKDVPTETPEGLMLSAFTEREDTRDVIISKNGESLKTLKQ
DAKIATSSLRRTSQLLSMRPDFQMGDIRGNLNTRFKKFDESDFDAMMLAYAGVHRLNFGD
RISEILPHEVMLPAVGQGALGIETRVDDEATKEIVSVMNNVNTEFCTKAERALLRHLQGG
CQIPIGSYASLKNGNLHLLAYVGSVDGKRTIRNEITKENCTLPEQAEQAGIELAEELLKQ
GANEILAEIRKTC
>Q8FSF7|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)|Swiss-Prot
MTLRIGTRGSKLATTQAGHMRDRLKHFGRDAELTIVTTPGDVNMSPVERIGVGVFTQALR
DALVADEIDVAVHSFKDLPTAPDPRFHLVVPTRADARDALIARDGLTLEELPEGAKVGTS
APRRISQLKALRPDLEILPLRGNIDTRMGKVTSGELDAVVLAFAGLSRVGMQDRATQVFD
PDMLMPAPAQGALAIECRVEDEDIITGLNMLMHADTYVTAVAERTVLNRLEAGCTAPVAA
HATLDGYAGDTMTLTAGVFALDGSEQLVFSAQGAGERPEELAEQVAAQLIEQGAATLLG
>B7NTE0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O7:K1 (strain IAI39 / ExPEC)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDNLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B5EBG8|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622)|Swiss-Prot
MALKELRIGTRASQLALWQANWVKSELEKRYPDMTVTLTKIKTIGDKILDVPLAQVGGKG
LFVKEIEEAMLRGEIDIAVHSMKDVPTEFPEGLGLYCITEREDPRDAVISNGVKFADLPQ
GARIGTSALRRQAQLLKVRPDLEMVIIRGNVQTRMDKLKTEGLDAVILAAAGLNRLGFAD
QITEMLPTDLSLPAIGQGALGIECNLSNQDVKDAISFFNSPDTSRAVRAERALLWRCEGG
CQVPIAAFGEVTGDQLKLTGFIASVDGKVSVKGVVTGPADDCEKLGVKLAEQLLSEGGHA
ILAEVYQREVSREKEIPV
>B5XYL1|hydroxymethylbilane synthase|EC 2.5.1.61|Klebsiella pneumoniae (strain 342)|Swiss-Prot
MLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLNVELVPMVTRGDVILDTPLAKVGGKG
LFVKELELAMLEGRADIAVHSMKDVPVEFPEGLGLVTICERDDPRDAFVSNHYASIDELP
AGSVVGTSSLRRQCQLAATRPDLVIRSLRGNVGTRLSKLDNGEYDAIILAAAGLKRLKLE
ARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTQALLAPLNHAETAVRVRAERAMNTRLEG
GCQVPIGSYAELVNGELWLRALVGAPDGSQMVRGERRGPAEQAEALGISLAEELLDNGAR
DILAAVYDGEAPR
>A4YD92|hydroxymethylbilane synthase|EC 2.5.1.61|Metallosphaera sedula (strain ATCC 51363 / DSM 5348)|Swiss-Prot
MKIRIAARGSKLSLKQVEIVTTYLQAKGYETEFIEIKTKADLFGNKPLHEIGKGVFEKEV
NEAVLQGRADIAVHSMKDMSSELPPGLELLATPKRENPVDVLVSELNLEELPEKSRIGTG
SLRRANFLKVVRPDLVVENIRGNVDTRLRKYRDHEYDGIILAEAGLRRLGVEVKRFPLDV
ESFTPEPNQGIIAVVGSPKFLGLFQELNDTGTMKEALAEKETVKVVGGGCHSPLGVLFRL
EDDVLHGIASYSNGVKRVTVKLSTRESPQIAGNQLGKALVKAMKDEGLIP
>Q8CXC0|hydroxymethylbilane synthase|EC 2.5.1.61|Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)|Swiss-Prot
MRKIIVGTRKSNLALTQTEWVIDQLKKAGVKNEFEIKKIVTKGDQILDVTLSKVGGKGLF
VKEIEKAMFDKEIDLAVHSMKDMPAVIPEGLTISSIPEREDHRDAYLAKDNILLQDLPEG
AIVGTSSLRRGAQILAERPDLTIKWIRGNIETRIRKLQEEDYDAIILAVSGLKRVGLSEE
LITEYLEPEVCVPAVGQGALAIESREDDEELTNIVKKIHDAYTAKTVSAERTFLHLLEGG
CQVPIGGYAYLDGDEVVLTALVGDPDGTTILKETVRGTEPTEVGKEAAELLISQGAKEIV
DRVKEEMDQ
>Q7V697|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain MIT 9313)|Swiss-Prot
MVLTQLRIASRRSQLAMVQTNWVQAELEQAHPGLSISVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGRADIAVHSLKDLPTNLPEGLMLGCVTEREDPADALVVNQKNAEHQLD
TLPEGAIVGTSSLRRLAQLRHHYPHLVFKDVRGNVITRLEKLDAGNYDCLILAAAGLTRL
GFGDRIHQLIPSEISLHAVGQGALGIECVEGHPEVLEAIKALEHKPTAQRCLAERALLRE
LEGGCQVPIGVNSRIEANELLLTGMVASLDGKRLIRDQQRGPIDRCEAIGKELAETLKSQ
GAGEILAEIFAAVRPEA
>Q21XQ9|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)|Swiss-Prot
MSTLTIATRESRLALWQAEYVQDLLTRRGHQVGLLGMTTLGDQILDRALSKVGGKGLFVK
ELEVALEDGRADLAVHSLKDVPMELPDGFALACVMEREDPRDAFVSNQYANLASLPQGAV
VGTSSLRRMALLRALRPDLKIEPLRGNLDTRLRKLDDGMYAAIVLAAAGLKRLGLSQRIR
ATFEPTDMLPAAGQGALGIEVRSQRQDVIDALAPLAHHTTWLAVSAERAVSRAMGGSCSM
PLAAYATLAADILTIDAAWGDPDGKLALVHVRASAAVSDLASATALGARVAADLRAAVLA
NGGTLLVADAPQGQA
>A6WTG0|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella baltica (strain OS185)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLDDLADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELP
LGATVGTSSLRRQCQIRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRINDERVKALLAPLEHLETRYRVLAERAMNTRLEG
GCQVPIGAFAEIDGDEMTLRGLVGNPDGSEIIEGVITGPKTEATQLGVALAEELLSKGAK
TILDAVYAKA
>B9DNE1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus carnosus (strain TM300)|Swiss-Prot
MRKLVVGSRRSKLALTQSRQFIERLKKVEPDLDIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQQELFDHEIDMAIHSLKDVPSELPDGLTLGCIPDREIPLDAFISKNHVQLADLPDG
SIVGTSSLRRGAQILAKYPNLEIKWIRGNIDTRLSKLETEDYDAIILAAAGLRRMGWSDD
IVTEYLDPELLVPAIGQGALGIECRSDDTELLDLLSKVHNQEVAECVTAERTFLKEMNGS
CQVPIGGYATIDDNGRLTFTGLIMSPDGKQRFEQTATGNDPVELGKEVSDILKEQGAKEI
IDALNEES
>Q47LA7|hydroxymethylbilane synthase|EC 2.5.1.61|Thermobifida fusca (strain YX)|Swiss-Prot
MSTTPARLGTRRSTMATNQSRRVAEILTARTGVPVELVLITSFGDITRAHLTQLGGTGVF
VSALRDALLAGEVEFAVHSLKDLPTAPTEGIVLAAVTERDDPRDALCARDGLKFADLPPG
ATVGTGSPRRVAQLAALRPDLRYVPIRGNAETRLGKVASGELDAVVLAYAGLHRVGRLDD
VTDVFDVDQVLPAPGQGALAVECRTADFTGPLRYLTAVDHLPTRAAVTAERVILAELEAG
CAAPVGAYAEFVAEDRLRLRAAVVATDGSQAVRAEQTVTVTEFPDAVQAATALGRQLAHD
MIEQGADQIVADAAAGRGES
>B0U2W8|hydroxymethylbilane synthase|EC 2.5.1.61|Xylella fastidiosa (strain M12)|Swiss-Prot
MPLLRIATRKSLLAMRQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIG
ARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQR
MTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRQCVVAERTMNRALHGSC
HVPVGAYASYGVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAEL
LAATA
>Q8UC46|hydroxymethylbilane synthase|EC 2.5.1.61|Agrobacterium tumefaciens (strain C58 / ATCC 33970)|Swiss-Prot
MQTKPFRIGTRGSPLALAQAYETRSRLMAAHGLPEEMFEIVVLSTKGDRITDRALSEIGG
KGLFTEELENQLLSGELDIAVHSSKDMPTVLPEGLHLSAFLPREDMRDAFIGRTAPKLLE
LPQGAVVGSASLRRQALIRRLRPDLNVIVFRGLVDTRLRKLEEGQADATLLAFAGLKRLG
KDNVPTEILDPKEFPPAPAQGAIGVESRIGDARMDKLLAPINDRPTYDAVTCERAFLAAL
DGSCRTPIAGYATCEGDNLHFSGLILTPDGQTSHGVEISGNRRDALILGKKAGEEVRAKA
GSNFFEGWS
>Q5WEP5|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus clausii (strain KSM-K16)|Swiss-Prot
MRKIVIGTRRSKLALTQTNWVIDQLKQLGVPYEFEVKEIVTKGDRILDVTLSKVGGKGLF
VKEIEAALRSGEIDVAVHSMKDVPSELLEEFTLAAITEREDPRDVLVSENGHTLDELPAG
AIVGTSSLRRSAQILHRRPDVQVKWIRGNVETRLRKLKEEDFSAIVLAAAGLKRLGYGED
VITEYLDKDVCLPAIGQGALGLECRVDDVETTELLAKLHHEETGKAVLAERAFLKEMNGG
CQVPIGGYATVLEDGAVFLTGLVGSPDGKTILKEGKCGMVADELGKEVSSLLTAQGAGAI
LEKVRSELEGS
>A1V5U0|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei (strain SAVP1)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>P28464|hydroxymethylbilane synthase|EC 2.5.1.61|Chlorobaculum parvum (strain NCIB 8327)|Swiss-Prot
MKKEIIIGTRSSPLALWQAEFTKAELSKRFPDMNITLKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKHLLAGEIDLAVHSLKDVPTGTPEGLVITSFTEREDTRDVIISKSGKGLMDLPQ
NAKMATSSLRRMSQLLSLRPDLEIMDIRGNLNTRFKKFDEGDFDAMMLAYAGVYRLEFSD
RITEILPHETMLPAVGQGALGIETRTDDAETREIVRVLNDDNTEMCCRAERALLRHLQGG
CQIPIGSFGSYIDGTLKLLAFVGSVDGKTGLRNEVTKAVKTPEEAEAVGIELAEILLSMG
AEKILADIRKTC
>Q6NJK0|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)|Swiss-Prot
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>Q8XAP3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q8RFP5|hydroxymethylbilane synthase|EC 2.5.1.61|Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)|Swiss-Prot
MKKNIIIGSRGSILALAQANLVKDRLQGNYPNLSFEIKEIVTSGDKDLKSNWENSDISLK
SFFTKEIEQELLDGEIDIAVHSMKDMPAVSAKSLICGAIPDREDPRDVLVSKNGLLVTLP
QGAKVGTSSLRRAMNLKTVRPDFEIKHLRGNIHTRLKKLETEDYDAIVLAAAGLKRTGLA
DKITEYLNGEVFPPAPAQGVLYIQCRENDEEIKEILKSIHNEAIAKIVEIEREFSKIFDG
GCHTPMGCYSQVNGDKIKFTAVYLDEGKQIRAVVEDDLAKGKEIAYMAAEEIKNKIVK
>A8AAB4|hydroxymethylbilane synthase|EC 2.5.1.61|Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)|Swiss-Prot
MKIKIAARGSKLSLKQVSMFTSYLLKFFPDLEYEVITVKTTGDKANAPFEELAKRGLTGL
FEKEVNKAVLEGKADVAVHSLKDLPTELDPRLEIAAFLPRDPPYDVLISRAGNYDIFDLP
KGSVVGTSSARRKALIKNLRPDLVVKDLRGNVDTRLEKLRRGEYDAIVLAEAGVSRLGLN
VDYVRLDWRLFPPSPGQGIIVAVTRKGSEISDLLKSISDVKSEKLATAERTVLKEFGGGC
FVALGAIAFEEGSLIRLRATVLSPSGRERVDVELIGKGPEEVGMRAAERLKALNPMKTTV
GSEE
>Q8PW57|hydroxymethylbilane synthase|EC 2.5.1.61|Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)|Swiss-Prot
MIIGTRGSQLALAQTENVARLLKEKGVETSIKIIKTSGDRFTDRPLHAVSGGVGAFVREL
DDVMLAGEIDIAVHSMKDMPTIRPKAIPTVAVLKRDTPFDILLTYDGTPLDELPEQSIIG
TSSLRRTAQIRRYRPDIITQNLRGNIDTRLRKLREGQYDGIMLAKAGLERMGWEIEGEIF
SPDFFCPSPNQGTVAVVTREGTEAEAAVSMLDHTESRIVTEIERILIAELGGGCTTPVGS
YAEITPDRQEIHVRAEVLSLDGREAIRIDEFIPLRGGIEKARELGHRLVEMGGRRLAEEA
LLQISRGADSENSCDY
>Q8YVU6|hydroxymethylbilane synthase|EC 2.5.1.61|Nostoc sp. (strain PCC 7120 / UTEX 2576)|Swiss-Prot
MTSVVSSARRTIRIGSRKSQLALVQTYWVREQLQNSFPDINFEVHTMSTQGDKILDVALA
KIGDKGLFTKELEVGMINEEIDFAVHSLKDLPTNLPEGLALAAITERENPADALVVHENF
KDKQIDTLPAGAVIGTSSLRRLAQLRNQFPHLTFKDVRGNLNTRLAKLDAGEYDGLILAA
AGLQRLGMGDRVHQILPKEISLHAVGQGALGIECRADDAELITVLKAIEHPETRDRCLAE
RSFLRSLEGGCQVPIGVNTEINGNELILTGVVASVDGQNLVKDTVSGNASDAEAIGIRLA
ELLREQGAQEILNTIFAEIQRGS
>Q59684|hydroxymethylbilane synthase|EC 2.5.1.61|Proteus mirabilis|Swiss-Prot
MPKSTIRIATRQSPLAMWQALYVKEQLQIAHPSLVVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELALLSSRADIAVHSMKDVPIDFPEGLGLVTICEREDPRDAFVSNHYDSLEQLP
AGSVVGTSSLRRQCQLKALRPDLIIRDLRGNVGTRLSKLDNGDYDAIILAVAGLKRLKLT
ERIRSSLSAEQSLPAVGQGAVGIECRLDDHDTQALLAALNHADTATCVKAERAMNTRLEG
GCQVPIGSYAIWQNDKIWLRALVGAPDGKTILRGERLVSPEDAEQAGISLAEELLDKGAR
EILTAVYQGNTAI
>Q7UPN0|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodopirellula baltica (strain SH1)|Swiss-Prot
MAPTPPSDTTRLRIATRESPLAMWQAEHVAKLLKKHGFQTEIVPLVSKGDTDMRPIDGTR
QVGLFTKRIQQALVDDEADVAVHSLKDLPTEPDSRFVLAAVPPRESVLDALVFADNSPHL
ESQTGAESPLDYLPQGARVGTGSTRRLAQLKQLRPDLEVLPIRGNVQTRLAKLNAGEFDA
IVLAHAGILRLEMTDLPHRLFPLDEMIPAPGQGALGIEVRSDDAGAMDAIANLNDAAARL
AATAERKVLSELHGGCLAPIACHAKLETSNHGTELCLRAIVMSADGEQRLQEDARITVQP
NDADLHVAEAHELGTLVAKRLRDKGADKLISTVRENH
>A3D9Q4|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella baltica (strain OS155 / ATCC BAA-1091)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLDDLADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELP
LGATVGTSSLRRQCQIRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRINDERVKALLAPLEHLETRYRVLAERAMNTRLEG
GCQVPIGAFAEIDGDEMTLRGLVGNPDGSEIIEGVITGPKTEATQLGVALAEELLSKGAK
TILDAVYAKA
>Q8NW74|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain MW2)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q8DIE4|hydroxymethylbilane synthase|EC 2.5.1.61|Thermosynechococcus elongatus (strain BP-1)|Swiss-Prot
MIATSSRPVRIGSRKSQLALVQTEWVQAQLQTHHRDRAFEVVTMTTQGDNILDVALAKIG
DKGLFTKELELSMLRGETDLAVHSLKDLPTQLPDGLVLAAITEREDPADALVLGAKWTGH
TIDTLPEGTVIGTSSLRRLAQLRHYYPHLTFKDVRGNLNTRLAKLDAGEYDALILAVAGL
RRLGFGDRISQVLPATVSLYAVGQGALGIECRAEDADILALVKTLEHPETTARCLAERAF
LRQLEGGCQVPIGVHTVIENGQLTLTGLVASLDGQRLVKDSLTGDVATAEELGTRLALKL
REQGASEILEEIFATVRPER
>Q9PCX7|hydroxymethylbilane synthase|EC 2.5.1.61|Xylella fastidiosa (strain 9a5c)|Swiss-Prot
MPLLRIATRKSLLAMWQSEYVAARLRMLRPDLDVVLVPMSTRGDEILDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIG
ARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQR
MTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRQCVVAERTMNRALHGSC
HVPVGAYASYEVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAEL
LAATA
>B9IZ39|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain Q1)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKEKVVGTDPEKVGLEAADRLINQGAKEL
ILAANKEQQ
>B8D8B0|hydroxymethylbilane synthase|EC 2.5.1.61|Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)|Swiss-Prot
MYNKTLRIATRKSPLALKQTKYVQKKILSLYPDLNIKLVPIVTHGDNILNKSLSKIGGKG
LFIKELELALLENKADIAIHSMKDLPVKITKELCLVSICKRGNALDSLVSNNYQSINQLP
KGAIVGTSSLRRQCQLITYRPDLIISPLRGNIETRIAKLDQGKYDAIILATEGLNRLRLK
NRITQIIPAELSLPSCGQGAIGIQSRLHDKKVLFFLSRLNHINTFIEINAERAFCRKLES
GCQIPIGSYAILKKNKIWLRGLVGSPNGKIILKGERIGCYNTGEKMGYSLADELLKNGAK
NILNNLHIKQSYCI
>Q3ACT3|hydroxymethylbilane synthase|EC 2.5.1.61|Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)|Swiss-Prot
MKKEVIVGSRDSALALWQTNWVVERLSKIHPEINFKIVTMKTKGDKILDVALAKIGDKGL
FTKELEHALLNKTIDMAVHSMKDLPTVLPEGLKIGAFCEREYPGDVFISPKGFKFLELPQ
GARIGTSSLRRIAQILAVRPDLQAIPLRGNLPTRFRKMEEMDLDGIILAYAGVKRLGYED
KITEMLSFDLCLPAVGQGSIGVEIRADDTFIEELLKPIDHFATNRAIRAERAFLKRLEGG
CQIPIGAYSEVKENRLHLKGVVASLDGKLVIKGEKEGSIEEPEKVGISLAEELLTKGAQK
ILEEIRRDANE
>A0Q2B1|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium novyi (strain NT)|Swiss-Prot
MKIVVGSRGSKLALTQTNWVIDKIKQKYPQIQFEVKIISTKGDRIQHIALDKIGDKGLFV
KEIEEQLISGDIDMAVHSMKDMSTEMPEELKFSYVPKREDYRDVLILNKKYNSIDELPMN
AKIGTGSKRRKYQLLQYRDDLNIVPIRGNVETRINKIEMENLHGVVLASAGIKRLNIQEK
LDYNIFYLNEDIMLPSPAQGILALEIRKDREDLEEILKSIEDKNSSIQAVAERAFLKGVN
GGCHVPIGAICNINKDNVELTGLLGKEDGSKIIRKSLGGKIEDAEKIGYELAEIVLKEIN
>Q72AV0|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)|Swiss-Prot
MKHLVIATRGSKLALWQAEHIKSLIETEHAGKVDVSLKIIKTKGDIILDVPLAKVGGKGL
FVKEIEEALLDGSADLAVHSMKDVPMELPEGLFLGCIPEREEPSDTLLSVRYASLDALPH
GARVGTSSLRRQSQLLALRPDLDIISLRGNVDTRLRKLMDGEFDAIVMATAGLKRLGLAA
PHHEVLAPPRFLPAVGQGALGIEFREDRADLRDMLAFLDHRPTRIRVEAERGFLAGLEGG
CQVPIAGHAVMTGDDNFRIEGLVADLKGERVIRRTLEGTGANARNRGLELASQVLADGAA
EILDEVYASGAADRQ
>A7N9H6|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)|Swiss-Prot
MKQITIASRESKLALWQTNFVKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>Q9ZMJ7|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain J99)|Swiss-Prot
MEKLVIGSRGSELALWQANHIKERLKKECSMESEIRIVKTTGDKILDAPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKFKRKDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLNVQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFITLQKLNNEESAFCCHLEREFIKGLNGGCQ
IPIGVHANLMGDEVKIRAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>Q8TT56|hydroxymethylbilane synthase|EC 2.5.1.61|Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)|Swiss-Prot
MIIGTRGSQLALAQTENVARLLKERGVETSIKIIKTSGDRFTDRPLHAVSGGVGAFVREL
DDVMLAGEIDIAVHSMKDMPTIRPEGLPTVAVLKRDTPFDILLTYDGTTLDELPEQAIIG
TSSLRRTAQIRRYRPDLITQELRGNIDTRLRKLKEGQYDGILLAKAGLERMGWEIDGEIL
SPDFFCPSPNQGTVAVVTRADPEIEAAVSGLDHTESRIVTEIERILISELGGGCTTPIGS
YAELTSDKQEIHIRAEVLSLDGKEDVRIDEFIPMLGGLEKARELGHRLVEMGGKRLAEEA
LLQISRNACGTENSFDY
>Q6MW51|hydroxymethylbilane synthase|EC 2.5.1.61|Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)|Swiss-Prot
MSEQKETVHIGTRRSALALRQVDLVIAALQPHHPNVHFQVHALATLGDKNQTASLPSLGK
GLWTNELEAKLFNKEVDFIVHCLKDMPTTLPEGGKIGVVTEREDPRDVVVMKKKWAEQGK
YKSLADLPEGAIVGTSSVRRAAQLRRRYPGLVFKDVRGNIETRMRKCDEEDYDCIILAAA
GLLRMGYDERIAQWLDSTTEGGGMLHAVGQGALAMEIREGDEKTLEIIKPLCHEKTMVAT
FAERAVMRTLEGGCSVPIGVETKWVGEDQLQLKVTVVSLDGKESVDGQSVEVIKTIEEAE
AMGQKLAEDLAKRGAQKILDFVNQGRASGGALKIGDL
>A8G3L1|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain MIT 9215)|Swiss-Prot
MTNFKLKIASRRSKLAMVQTLWVKDQLERNIPNLDVSIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGHADIAVHSLKDLPTNLPNGLKLGCITKREDPADALVVSKKNDYYKLE
TLPEGSIVGTSSLRRLAQLRNKYPHLVFKDIRGNVITRIEKLDAGEFDCIILAAAGLKRL
GFESRIHQIIPSEISLHAVGQGALGIECKSDDKKVLEIINVLEDKPTSQRCLAERAFLRE
LEGGCQVPIGVNSNIDNGQLYLTGMVASLDGKKLIKDQVIGNINNPELVGIELAKRLKLQ
GADKILSEIFEEFRENKN
>A4WN24|hydroxymethylbilane synthase|EC 2.5.1.61|Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)|Swiss-Prot
MRLVVATRGSKLSMLQTEELLAQIKAVEPSIEFEIKIVKTTGDEVQDKPLYQIGVKGIFE
KEVNLAVLRGEADVAVHSLKDLPSELSPGLVLAGFSKRAPPFDAVVSTAGYVLETLPRGA
LVGTSSVRRAEFVKAIRPDVRVEPLRGNVDTRINKILQGKYDAAIMAVAGIYRLYGASPP
IKLAVLRPEVLPPPPGQGIVAAVVREADSWLIDLLKKASDPKASLEAIAEREFLKAVGAG
CHVAIGGVAFARNDTVEFIAGYASGGRKYIVRVVGDDPVEVGRRAAEEIRKFKDGDV
>Q5HFA2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain COL)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>A5GSE0|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain RCC307)|Swiss-Prot
MTASSLRIASRRSQLAMVQTEWVRDELANAHPGLEISIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVNRADIAVHSLKDLPTNLPEGLMLGCITEREDPADALVMHAKNKDLTLA
TLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVITRLEKLDSGQFDCLILAAAGLGRL
GLGDRIHELIDPSISLHAVGQGALGIECRDGDAAVLEQIKVLEHRPTSLRCLAERAFLRT
LEGGCQVPIGVNTRFEGDELVLTGMVASLDGKQLIRDELRAPQDQAEDLGNRLAELLRSQ
GAGEILAKIFAEARPEA
>Q4UYZ4|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas campestris pv. campestris (strain 8004)|Swiss-Prot
MTTLRIATRKSPLALWQSEHVATALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDAPFVLPAILERGDPADALVSNLYATLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEAR
ITARLDAPEWLPAPAQGAVAVECRGDDARIHDLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAAFARWEGEDLFLQGMVGSASDGRLIHAEAHGSPDATEDLGRLVADGLFEKGAAQL
LAEL
>A7Z7A5|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus amyloliquefaciens (strain FZB42)|Swiss-Prot
MRTIKVGSRRSKLAMTQTKWVINKLKELNPSYNFEIREIVTKGDRILDVTLSKVGGKGLF
VKEIEQALLHQEIDMAVHSMKDMPAVLPEGLVIGCIPKREDPRDALISKGHQKLDGIKEG
GIIGTSSLRRSAQILAERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKDD
VVSEFLEPDRCLPAVGQGALAIECRESDEELLKLFAQFTDEYTQRTVAAERAFLHAMEGG
CQVPIAGYASVNDRDEVELVGLVASPDGKTIYKETAAGHDPEEIGKRCAAMMSEKGAKAL
IDSVKQELDQDGK
>C0ZAH1|hydroxymethylbilane synthase|EC 2.5.1.61|Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)|Swiss-Prot
MGKWKVGTRRSKLALTQTNWVVDKLKGFAPEADFELHEIVTKGDRILDVTLSKVGGKGLF
VKEIEQSLFDKETDFAVHSLKDMPAELPDGLVIGAIPKRVDPRDVLLSKDGKTLDELPQG
ALVGTSSLRRSSQILAYRPDIQIESLRGNIDTRMRKLAEGNFDAIILAAAGLERVNFEGE
ISQFLPVEISLPAVGQGALAIECRADDEETLALLKQFDDAPTRLAVSAERSFLHKLQGGC
QVPIGAYATVGENNEITLTGMVGSPDGKQMFKNTATGQDPLALGIQVAEALLAQGAGDVL
AEVLRENEQ
>A7ZD37|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter concisus (strain 13826)|Swiss-Prot
MKEIKIATRKSILALWQSEHIKARIEAQHKGMKVVLEGMKTKGDVILDTPLAKIGGKGLF
TKELEDSMLKGETDIAVHSLKDVPVVFPEGLRLAAICSREDTRDAMISEKFAKFSDLPHG
AKVGTTSLRRKMQLLIMRPDLEIISLRGNVQTRLRKLKEGEFDAIILAMAGINRLNIKAE
VAHIYTFGFDEMIPAMGQGALGIEARDEKQILDETSFLNDENAVIETTIERDFVSVLEGG
CQVPIGISARLKGDEISIDAIVGLPDGSEYIKDSLKTSKDKFQSVGKELAHKFIEKGARE
LLKRAEEMA
>A6LSY5|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)|Swiss-Prot
MNKLTIATRKSKLAQTQTEIIMKSLKDKFNIDSEKMLIVTEGDRKLDVSLAKIGGKGLFV
KDIEIALLEKRADGAVHSMKDVPYELSHEFEIAAITEREDIRDVLISKDNIPFKELRKGA
IIGTSSIRRACQLKLMRNDLDIVPIRGNVQTRLEKMKEQNLDGIILASAGLKRLNEEDII
TEYFDPKVFIPAVAQGALGIECLKTSSAKKYFEKMEDSNAKLTVEAERSFMRMLNGDCHS
LIGAYSEIQGNDLYMIGIYDIGGRIVKKDILGDKNDHIELGRKLANKILEI
>Q6BM23|hydroxymethylbilane synthase|EC 2.5.1.61|Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)|Swiss-Prot
MPHNTKSMDNTLNIKDNHVQIGGRKSKLAVVQSEIVKECIVEKFPELSCSVLALSTLGDK
VQSKPLYSFGGKALWTKELEILLLEQVEEYPRLDLIVHSLKDIPTNLPEEFELGCILNRE
DARDALVMKSGSSYKSLADLPDGSLVGTSSVRRSSQLLKNHPKLRFDSVRGNLQTRLNKL
DDENSPFECLLLASAGLIRIGLGDRITAHLDAPEMYYAVGQGALGIEIRKGDEKMLQLLK
TIEDLPTTYCCLAERSLMRHLEGGCSVPIGVQSHYNESTNELSLKAIIVSPDGIHFVEDE
YKGVVNNKDDADAIGIKVGDLLSAKGGREILNSINFERINLPPSSNTPTPQPITPITTNN
S
>Q2GGC7|hydroxymethylbilane synthase|EC 2.5.1.61|Ehrlichia chaffeensis (strain Arkansas)|Swiss-Prot
MNIRIGTRGSILAIAQTLEIKNLLNRYFPEISVQIVKIKTSGDINNQVPLSAIGGKSLFI
KEIEEALLMGKVDLAVHSVKDIPAFYCEGLIIPCVLKRNSPYDVFISSKHKDIKSLPLNA
TIGTSSVRRKVQLNYLRPDLQVVPVRGNIDTRILKANVGEFDGIVLAEAGLIRINRCDVI
KEILSPKIMLSAVGQGAIGIQCRVDDHSIINKIKVLNCHQSYVCVMAERSFLKTINGSCD
TPLAALAQYVNNDTIHMSCMLANEKNMVFASCCFNECDAEKSGINMGKKLMDELSQYY
>Q7NGF7|hydroxymethylbilane synthase|EC 2.5.1.61|Gloeobacter violaceus (strain PCC 7421)|Swiss-Prot
MSRTVIIGSRDSQLALVQTHWVRDELQRAHPDIRFEIVEMKTQGDKILDVALAKIGDKGL
FTKELESAMLEKRTDLAVHSLKDLPTALPPGLILGAITEREDPSDAVIVRRGLEAAGLAD
LPEGAVVGTSSLRRLAQLKHHYGERLRFQDIRGNLNTRLRKLDEGRYDAIVLAVAGMRRL
GWSERISEVLSPDISLHAVGQGALGIECREADGEILDLLTVLNHPPTARRCRAERAMLRA
LEGGCQVPIGVYTELDDSGRLTLQGIVASLDGRNMARACRSGPGDAPEALGRAVAEDLKA
AGAQAILDQIFVLVRSPGVIAPGAAPAS
>Q5WT65|hydroxymethylbilane synthase|EC 2.5.1.61|Legionella pneumophila (strain Lens)|Swiss-Prot
MSAKIIRIATRQSPLALWQANHVREMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKG
LFVKELEEALLDKRADLAVHSTKDMPAQLPDGLSLAAICKRDNPFDALISPQFKSLDALP
KNAIIGTSSLRRQSQLLAYNPNLQVKTLRGNIHTRLSKLESGEYQAIILAAAGLERMGLA
HHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIYGLNDPISALCVHTERRVNAKLGG
NCHIPFAVYCTITAENLLLLRAKVLNLDGSQMIDDEQQGKIEEAEIIADRCTESLMTKGA
MTLLSTIPS
>A4T340|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium gilvum (strain PYR-GCK)|Swiss-Prot
MIRIGTRGSLLATTQAGTIRDALIAAGHDAELVIISTEGDRRADEPIADIGVGVFTAALR
EAIADNVVDAAVHSYKDLPTAVDPRFMIAATPVREDARDALVARDGMVLGELPAGSVIGT
SSPRRVAQLKALGLGLEIRPLRGNLDTRLNRVSSGELDAIVVAKAGLSRIGRLEVVTETL
EPVQMLPAPAQGALAIECRAGDTALAQLLAELDDADTRAAVTAERTLLAELEAGCSAPVG
AIAEVVESIDEDGRVFEELSLRGCVATLDGSDVIRASGIGSPDRARELGLSVAAELFDLG
ARDLLDERGRDT
>Q3A009|hydroxymethylbilane synthase|EC 2.5.1.61|Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)|Swiss-Prot
MSSSALRIGTRASRLALWQAEWVQQQLETLHPGLSVVLVPITTKGDKILDVPLAKVGGKG
LFVKEIEEALYDGSIDLAVHSMKDVPSVLPPGLILPCIPPREDPRDALVTPDGRSFAQLP
QGARIGTSALRRQAQLLHRRPDLDIVSLRGNVETRLRKMEEEDMDGIVLAAAGLKRLELA
ERIAEYLSVDVSLPAIGQGALGLECREGDDRTLELIAPLHDADTAVAVRAERAFLRRLNG
GCQVPLAAHATVAEQTLTMVGLVAEVDGGSLIKETLAAPVAQAEAVGCQLAETLLARGAD
RILAALDITPTPLVP
>Q1I316|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas entomophila (strain L48)|Swiss-Prot
MSTREIRIATRKSALALWQAEYVKARLEQAHPGLQVSLVPMVSRGDKLLDAPLAKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTFKSLEALP
AGSVVGTSSLRRQAQLLARRPDLEIRFLRGNVNTRLAKLDAGEYDAIILAAAGLVRLGFE
DRITSTISVDDSLPAGGQGAVGIECRSADSEIHALLAPLHHIDTADRVVAERALNKRLNG
GCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRASAEALGVQVAEDLLSQGAE
AILKEVYGEAGHP
>C4K265|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia peacockii (strain Rustic)|Swiss-Prot
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMYNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>Q0HQI7|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella sp. (strain MR-7)|Swiss-Prot
MSENRIRIATRKSPLAMWQAEFVKAELERVHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELP
LGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEG
GCQVPIGAFAEIHGDEMTLRGLVGNPDGSEIIEGVITGPKTEATKLGVALAEELLSKGAK
SILDAVYAKA
>C4KIZ9|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)|Swiss-Prot
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIIDIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLERDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNEDIIP
>Q9KVM1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)|Swiss-Prot
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>A9R8K0|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis bv. Antiqua (strain Angola)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSLGAR
EILAAVYLDNPAR
>A0RJ81|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus thuringiensis (strain Al Hakam)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>Q57B08|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella abortus biovar 1 (strain 9-941)|Swiss-Prot
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDVLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>A7I1S0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A)|Swiss-Prot
MNKLRIATRGSALALWQSKYIQNLIENNTEVEVELQSMKTKGDVILDTPLAKIGGKGLFT
KELEESMLRGESDLAVHSLKDVPVVFPKGLILTAISEREDVRDSFVSEKFASFNELPKGA
KVGTTSLRRKMQLLIKRPDLKIISLRGNINTRLRKLKENEFDAIILASAGLKRLNLMENI
KYFVPFSLDEMIPAMGQGALGIECVDKSEVIEILKFINNENSVIATTIERDFVAKLNGGC
QVPIGVNAEISGDIIKVRAIVGLPDGSEFIKDKREISKADFKNFGTKLADEFISRGAIEL
LKRAEEMA
>A5I0B2|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)|Swiss-Prot
MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGVILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGISLAEHILKD
>Q1J288|hydroxymethylbilane synthase|EC 2.5.1.61|Deinococcus geothermalis (strain DSM 11300)|Swiss-Prot
MRTVTVGTRGSALALAQTRWVVARLKEEWPDTDFRIQTISTKGDRDRAALQSLAQKGDKG
FWVKEIEDALLAGRIDIAVHSLKDLPTEQPEGLEIASIPKRVDARDVLIGKDGMKRLEDL
PSGARVGTSSVRRKAFLRAYRPDLQILDLRGNIDTRLAALGTPDYDAIVLAAAGLIRTEM
RHRIDEFIDPDLLLPAPGQGALALETRADDDLSIEVVYAIHDHATDDRVTAEREFLAGLG
AGCMAPVGAHATLKDGVLTLEGWVGALDGSQVIRATTSGDPAECADLGAELAADMLGQGA
QQLIEAAHR
>Q6CZG3|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia carotovora subsp. atroseptica (strain SCRI 1043 / ATCC BAA-672)|Swiss-Prot
MLANIIRIATRQSPLALWQARYVQQCLNHFYPDLHVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPVEFPDGLGLTTICERDDPRDAFVSNRYDSLEQLP
EGSCVGTSSLRRQCQLRARRPDLVIRDLRGNVGTRLAKLDNGEYDAIILAVAGLKRLGLE
ERIRCALSPEESLPAVGQGAIGIECRLDDDRIRQLLAPLNHTDTAARVLAERAMNVRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIVGERKGSVSDAEKIGVALAEELLAKGAS
AILQAVYQGQSSS
>Q2SQ70|hydroxymethylbilane synthase|EC 2.5.1.61|Hahella chejuensis (strain KCTC 2396)|Swiss-Prot
MPKQHLVIATRQSALALWQAEHVKQRLEALHPGLTVELLGLTTKGDIILDTPLAKVGGKG
LFVKELETAMLEGRADIAVHSMKDVPMEFPPGLGLGAILERETPMDAFVSNQYASLDELP
EGAVVGTSSLRRQCQLSERRPDLKILSLRGNVNTRLAKLDAGDFDAIILAASGLKRLGFS
GRIREELTPEVSLPAVGQGALGIECRLDDPEAMALIAQLQDAETTARVSAERAMNHRLQG
GCQVPIAGYAEITGDQMRLRGLVGSPDGAQVLRDEVEGPVAAAEALGTELAERLLQQGAG
KILEAVYGNHS
>C1KVK3|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 4b (strain CLIP80459)|Swiss-Prot
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEVIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNRVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEVVHFKGLVGNADGSIILASEQAGANPSEIGNKVAEDLLSEGAD
TIIKELRNI
>Q73SS0|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)|Swiss-Prot
MIRIGTRGSLLATTQAGGVRDALIARGHPAELVTITTAGDRSSGPIESLGVGVFTTALRE
AIEEGRVDAAVHSHKDLPTADDPRFAVAAIPARNDPRDAVVARDGLVLAELPPGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLGDVTETLE
PVQMLPAPAQGALAVECRAGDSRLAAVLAELDDADTRASVTAERALLAELEAGCSAPVGA
IAEVVESIDEDGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFELGA
RELMSGARHDPARGN
>A1AUE7|hydroxymethylbilane synthase|EC 2.5.1.61|Pelobacter propionicus (strain DSM 2379)|Swiss-Prot
MPPRQLRIGTRASQLALWQANWVKSELEKRYPAMEVTLTKIKTMGDRILDVPLAQVGGKG
LFVKEIEEAMLRGEIDIAVHSMKDVPTEFPEGLGLYCITEREDPRDAVVSRAARFSHLPP
GARVGTSALRRQAQLLHARPDLEMVTIRGNVETRIRKLDEENLDAVILAAAGLKRLGLTQ
RVAEYLDVEFSIPAIGQGALGIECRLSDPVVTEAIAFFNHPDTSHAVRAERALLRRCQGG
CQVPIAAHGTIRGGELRLVGLIAAVDGREFVRDEISGPVDQCEHLGEELADRLLSRGGRA
ILEEVYQREI
>A5VWX3|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas putida (strain F1 / ATCC 700007)|Swiss-Prot
MSTREIRIATRKSALALWQAEYVKARLEQAHTGLQVTLVPMVSRGDKLLDAPLAKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTFDSLETLP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSTISVDDSLPAGGQGAVGIECRSADVEIHALLAPLHHVDTADRVIAERALNKRLNG
GCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRAAAEALGVQVAEDLLGQGAE
AILKEVYGEAGHP
>Q68WR3|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia typhi (strain ATCC VR-144 / Wilmington)|Swiss-Prot
MINSIRIGTRNSTLALIQTNLVIAQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGRIPVDLVIAAVLEREDPRDVLVCLNYKSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDATILSYAGLKRLNAFN
KKYCHLIEYSQILPCVGQGVIAVEIRKDDNAMFNICNQINHIPTFELIKPERAFLEHLDA
NCSTPIGAYSQYLDAYNIQTDFMLGKLDCNKIIFQTEITNINTSRECGIKAAKMMLAQQ
>Q83PH4|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>C3NF70|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)|Swiss-Prot
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIIDIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLKRDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNEDIIP
>A7MXU9|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio harveyi (strain ATCC BAA-1116 / BB120)|Swiss-Prot
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQLKEYRPDLVIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHQDTADRVRCERAMNLTLE
GGCQVPIGSYSLLDGDNIWLRALVGEPDGSLIVRGEIRGHRNDAEALGVQLANELLENGA
RDILTKLYADHE
>Q66G00|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pseudotuberculosis serotype I (strain IP32953)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVAICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
TRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>Q72ZW2|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain ATCC 10987)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>Q8YJB0|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)|Swiss-Prot
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDVLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>Q9PHW9|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)|Swiss-Prot
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>A7GBW3|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)|Swiss-Prot
MNFIIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPKREDVRDAFISLDNIKFKDLRKGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLEHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
>B1I4L8|hydroxymethylbilane synthase|EC 2.5.1.61|Desulforudis audaxviator (strain MP104C)|Swiss-Prot
MRREVVVGTRGSRLALAQADWVIDHLRARYPRVSFVRKEIRTTGDNILEVALAKIGDKGL
FTKELEQALLHREIDLAVHSMKDLPTGLPEGLVIGAVSVREYPGDVFISRGGERLEELPA
GAVLGTSSLRRTAQLLAYRPDLQVIPVRGNVQTRLRKLDEGVVDALVLAWAGLFRLGLTE
RVTHRIPVAMCLPAVGQGALGIEARADDAEILEMLRTIDHAPTRAAVQAERTLLRRLEGG
CQVPVGALGRFRDGRLVLEAVVASLDGTELVRAQESGPADRPEALGNSLAVRLLEMGAGE
ILARVRAGA
>C4Z552|hydroxymethylbilane synthase|EC 2.5.1.61|Eubacterium eligens (strain ATCC 27750 / VPI C15-48)|Swiss-Prot
MHYRIGTRGSKLALVQSEYVKRRMEEAYPEDTFELVIIKTTGDKVTDKPLAAIGTKGFFV
KEIEEALLSGSIDMAVHSMKDMPAECAAGLTFAKAWKREDCRDVLILKTAGSFSELPSGA
VIGTGSLRRACQLAMLRPDIQFTAIRGNVDTRINKLMDDSYGLDGIVLAAAGLNRLGRSS
EITEYLDPEVVIPAPAQGVLAIETAEVNTELLDKINALSDDNSDREAVAERTFLRLTGGG
CHAPVGAHCVTKDNGDLRMVVLFGNDDCSRILRIEVTGTDSEAVGHEAARMLGLE
>C4K4E3|hydroxymethylbilane synthase|EC 2.5.1.61|Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)|Swiss-Prot
MSNNMIRLATRQSPLALWQAHYVKTGLEFFHPDLKVILLPMVTQGDNILGTALSKTGGKG
LFVKELERAVLDNRADIAVHSIKDMPLYFPEGLGLVAVCEREDPRDAFLSLRYHDVAQLP
EGSVVGTSSLRRQCQLYKNYPGIVVRDLRGNVGARLKKLDQGDYDAIVLAVAGLKRLGLE
NRMTQILRPETSLPAAGQGAIGIECRLDDTVTLQRVATLNHRPSQLKISCERALLKRLEG
GCQTPIGSYAEIENDELWLRAFVGAPDGQLIIDGERRGNFDSAEKIGFELANELLSRGAE
AILAQLNRQ
>Q8Y6X5|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)|Swiss-Prot
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEAIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNQVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPEVCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEFVQFKGLVGNADGSIILESEQVGANPSEIGNKVAEDLLSEGAD
TIIKELRNV
>A0PW29|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium ulcerans (strain Agy99)|Swiss-Prot
MIRIGTRGSLLATTQAAIVRDALIANGHAAELVTISTLGDRSSAPIETLGVGVFTTALRE
AIEDGRVDAAVHSHKDLPTAQDPRFTIAAIPPRQDPRDAVVARDGLVLGELPVGSLVGTS
SPRRAAQFRALGLGLEIRPLRGNLDTRLNRVSNGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAIECRAGDSRLATVLAELDDADTRAAVTAERALLAELEAGCSAPVGA
IAEVVESIDEEGRVFEELSLRGCVAALDGSDVIRASGIGTSGRARELGLAVAAELFELGA
RELMWGEGNSPQGS
>Q7MYN1|hydroxymethylbilane synthase|EC 2.5.1.61|Photorhabdus luminescens subsp. laumondii (strain TT01)|Swiss-Prot
MSTKTIRIATRQSPLAMWQALYVQQKLQQCHPDLEVQLVPMVTQGDVILDTPLAKIGGKG
LFVKELELALLEGRADIAVHSMKDVPISFPEGLGLVTICERDDPRDAFVSVKYHSLDELP
TGSIVGTSSLRRQCQLRELRPDLIVRDLRGNVGTRLNKLDNGHYDAIILAVAGLKRLKLH
ERIRTPLTAEQSLPAVGQGAVGIECRLDDQQTQTLLAPLNHYDTEVCVLAERAMNTRLEG
GCQVPIGSYAIWQDGKIWLRALVGAPDGSVIIRGERTALPKDACQAGVELAEELLERGAR
EILTQVYRGNPST
>Q88RE5|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas putida (strain KT2440)|Swiss-Prot
MSTREIRIATRKSALALWQAEYVKARLEQAHTGLQVTLVPMVSRGDKLLDAPLAKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTFDSLEALP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSTISVDDSLPAGGQGAVGIECRSADVEIHALLAPLHHVDTADRVIAERALNKRLNG
GCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRAAAEALGVQVAEDLLGQGAE
AILKEVYGEAGHP
>Q1AUK3|hydroxymethylbilane synthase|EC 2.5.1.61|Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)|Swiss-Prot
MAGRLVLGTRGSPLALAQAEACAAGLRAAGFAVELRRIRTTSDRRPDDPLSVIDQRDVFT
RQLDEALLAGEVDLAVHSMKDVPTEVPEGIVLAAVAGRADPSDALVSEGGWGVDGLPEGA
RVATSSLRRRAQLLHRRPDLRVVEIRGNVDTRIRKMRAGAAEAVVLARAGLVRLGLEVPH
AVIPHDVLLPAVGQGALAVAVRRGDPRLEEIRRALNDPAAEREVAAERALLRALEGGCRV
PVGARAVAGGRGVLLRGVVVSPDGAALCGGEERGEEPEEVGRRLAARLLERGAAGILGFV
RGVKP
>A7X391|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain Mu3 / ATCC 700698)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q980U4|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)|Swiss-Prot
MKILIAARGSKLSRVQVDMVGEKLRKIGIEYDVIDIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADVAVHSMKDILSEINPELEIFAVIERDPPYDILIAEKNLHKLDPNTTIGTS
SIRRKNFIKYIRPEINTKDIRGNVDTRIRKYLSKEYDGLILAEASIKRLNISISYHRLNV
YDFTPEANQGIIVVLGRKKDEKVKEVFKEITHKDTLDEALAERATISVVGGGCHSPIGVL
FRKEGKEFYGIASYSDGKKKITVSISKAGDPYTIGSELGLLLKKEMKNEGIIP
>Q8DD85|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio vulnificus (strain CMCP6)|Swiss-Prot
MTHSTPIRIATRKSPLALWQAYYVKDALQKAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYHHVDEL
PQGAVVGTCSLRRQCQLKAYRPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRTNDERILKLLEPLNHADTADRVKCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEIRGPRAQAEQLGVQLANQLLDEGA
REILTKLYQDHE
>B5ERN6|hydroxymethylbilane synthase|EC 2.5.1.61|Acidithiobacillus ferrooxidans (strain ATCC 53993)|Swiss-Prot
MPHSLRIGTRASPLAVWQAEHVRAALLRLHPGMAVEIITMTTSGDVLLDAPLHALGGKGL
FVKEIEDALQQRRVDVAVHSMKDVPALQPDGLEIVAIMAREDVRDAFVSNTFLHPDALPE
GARVGSSSLRRRAQLLERYPHLRVEDLRGNVATRLRRLDEGHYDAIILAAAGLKRLGLPD
RITHLLDIDRSLPAVGQGAIGIEARSDDRRTRELLAPLADADTQNCVLAERSMNQVLGGD
CRLPVAALARWQGPQMLLRGLVATPDGRRVLHAEAKGSDPVALGMAVAAALVAQGAAEII
EDVRNA
>Q6HD62|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus thuringiensis subsp. konkukian (strain 97-27)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDDE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSILLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>A3MLK5|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei (strain NCTC 10247)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>Q3AQF5|hydroxymethylbilane synthase|EC 2.5.1.61|Chlorobium chlorochromatii (strain CaD3)|Swiss-Prot
MKKQLIIGTRSSPLALWQAEFTKAELSKHYPDMEITLKLVKTTGDVLLDSPLSKIGDMGL
FTKDIEKHLLAREIDLAVHSLKDVPTSTPEGLIITSFTEREDTRDVIISKGGVKLKDLPP
NARMATSSLRRMSQLLSVRPDLDIRDIRGNLNTRFQKFDDGEFDAMMLAYAGVYRLNFSD
RISEILPHDMMLPAVGQGALGIETRVDDEQTREIVRILNHSTTEYCCRAERALLRHLQGG
CQIPIGAYATFSNGTLKLLAFVGSVDGKTALRNEITKTGLTSPEQAEEAGIALAEELLKQ
GADAILSQIRKTC
>A3DIF0|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium thermocellum (strain ATCC 27405 / DSM 1237)|Swiss-Prot
MKIRVGSRESKLAVRQAQIVIDSIKKYNPDIEIELVTMKTTGDKILDKTIDKIGGKGLFV
KELDRALLDGKVDITVHSFKDMPMDIDDRLPIVAVSKREDPRDVLVLPKGKNEIDFNGPI
GCSSSRRKIQIEKIYPGCTVEPIRGNVLTRLEKLDKGEYSAIALAYAGLKRLGLEERIWR
VFSTDEIVPAACQGIIAVQARKDFDASILANFHDKDSWDVSVAERSFIKALNGGCSSPSA
AYGVIQGEKIVLTGFYVDKNGKIYKMTKTGDRNQGEALGYSLAMEMLKGADA
>A5EW83|hydroxymethylbilane synthase|EC 2.5.1.61|Dichelobacter nodosus (strain VCS1703A)|Swiss-Prot
MSTLRIATRKSPLALWQAEHVAQQLKQHYPELTVELVPIVTQGDILAHTPLSKIGGKNLF
IKELEIAMQQNAADIAVHSMKDVGVTLPEGFVLAAILPRENPFDALVSNHYAHLNELPNG
ARVGTCSLRRKMQLAHYRPDLKLIDIRGNVHTRLQKLDSGAFDALILACAGLIRLQQNAR
IRQILPAEISLPAIGQGAIGVECRADSPFLAHIQTLNHFETAVCVQTERVVNQRLQGDCQ
VPIAVFATLSGKTMTLQSRIGTIDGQRMLAHQEICALEDAEKAGARCAEALIQQGAQDIL
HEYRK
>Q0BP15|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. holarctica (strain OSU18)|Swiss-Prot
MKQITIASRESKLALWQTNFVKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAILSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>A2BL26|hydroxymethylbilane synthase|EC 2.5.1.61|Hyperthermus butylicus (strain DSM 5456 / JCM 9403)|Swiss-Prot
MKLRVATRGSKLSIAQTMIALEAIKRVEPSLEYELVIVKTRGDIHQDKPFTAIGGKGLFE
KEVNLAVLEGRADIAVHSLKDVPSAISPGLVLAMTPPRDPPYDVLVVRGGKEKTIWDLPS
GAIVGTSSARRVAMLKHVRRDLVFKVLRGNVDTRLRKLEQGQYDAIVLAEAGLKRLGVDI
EYWRIPPDILPPAPGQGIIGVYTLSSRSDILPILEKASDQKAMAEARAERAFLAYAGGGC
HTPLGAYAELRGNTLYFHAALASPDGSRRVEVRVEGDPDKPTQVGLEAAFELRRLAAREG
ISL
>Q1GXA1|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)|Swiss-Prot
MNAPKTLVIASRESALAMWQAQYIQGRLQTLYPETEVTILGMTTTGDQILDSPLARIGGK
GLFVKELEQALADGRADLAVHSMKDVPMHLPPGFALAAISERDDPRDAFVSNDYPNLASL
PAGSIVGTSSLRRQSQLQARFPGLKVESLRGNLQTRLRKLDEGQYAAIILAAAGLKRLGL
ASRIRESIDPDNSIPAVGQGALGIEINAERLDLLKVLAPLNHPETAACVEAERGMSRALA
GSCQVPLGAFAQQHGDTLQMTGFVASIDGKEFLRESVQGPAEQPEALGQALAAKLVALGA
DRILAALPHE
>A6Q3S1|hydroxymethylbilane synthase|EC 2.5.1.61|Nitratiruptor sp. (strain SB155-2)|Swiss-Prot
MKLTIATRGSKLALWQSNHIKAQLESFGYEVELKIFKTKGDKILDTPLALIGGKGLFTKE
LEDAMLRGEADLAVHSLKDVPTELPEGLVLGAITKREMTNDSLLSEQYETLADLPPNAVV
GTTSLRRRMQLLHLRPDICIKDLRGNVDTRINKLKNGEFDAIILAYAGLKRLGILESVRY
VHPIDENTMIPAMGQAALGIECRPDVVDVVKKLNDEKSAIETFIERDFIDRLQGGCQVPI
GVRASLLENNDIIVKAVIGLPDGSELLKDKIFGSKENYHELGKELAESMIDNGAKELLQR
AEAMAFKEHK
>Q31C38|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain MIT 9312)|Swiss-Prot
MTNFKLKIASRRSKLAMVQTLWVKDQLEKNIPNLEVSIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGQADIAVHSLKDLPTNLPSGLKLGCITKREDPADALVVSKKNDCYKLE
TLPAGSIVGTSSLRRLAQLRNKYPHLNFKDIRGNVITRIEKLDAGEFDCIILAAAGLKRL
GFESRIHQIIPNEISLHAVGQGALGIECKSDDKKVLEIISVLEDKPTSQRCLAERAFLRE
LEGGCQVPIGVNSSIQNEQLYLTGMVASLDGERLIKDQYIGNIDDPEQVGKELAKKLKLQ
GADKILSEIFEQFREN
>P19356|hydroxymethylbilane synthase|EC 2.5.1.61|Rattus norvegicus|Swiss-Prot
MSGNGGAATTAEENGSMMRVIRVGTRKSQLARIQTDTVVAMLKTLYPGIQFEIIAMSTTG
DKILDTALSKIGEKSLFTKELENALEKNEVDLVVHSLKDVPTILPPGFTIGAICKRENPC
DAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDEQ
LEFSAIILAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVGVLHD
PETLLRCIAERAFLRHLEGGCSVPVAVHTVMKDGQLYLTGGVWSLDGSDSMQETMQATIQ
VPVQQEDGPEDDPQLVGITARNIPRGAQLAAENLGISLASLLLNKGAKNILDVARQLNDV
R
>Q09899|hydroxymethylbilane synthase|EC 2.5.1.61|Schizosaccharomyces pombe (strain 972 / ATCC 24843)|Swiss-Prot
MPSCTSFPIGTRKSKLAVIQSEIIREELEKHYPHLEFPIISRDTIGDEILSKALFEFKRQ
LAKSLWTRELEALLVTNQCRILVHSLKDLPSEMPDGMVIACIPKRSCPLDAIVFKAGSHY
KTVADLPPGSVVGTSSIRRRALLARNFPHLRFVDIRGNVGTRLAKLDAPDSQFDCLVLAA
AGLFRLGLKDRIAQMLTAPFVYYAVGQGALAVEVRADDKEMIEMLKPLQHQETLYACLAE
RALMKRLQGGCAIPIGVQTDVLAISNSSYRISLLGTVLSADGLRAAFGNAEAVVSSEEEA
EELGITVALALLKNGAGPILEEHQRSSDSEESLKNY
>Q6GG35|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain MRSA252)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>Q0AZ43|hydroxymethylbilane synthase|EC 2.5.1.61|Syntrophomonas wolfei subsp. wolfei (strain Goettingen)|Swiss-Prot
MRNLRLGTRGSQLALWQARHVASLLESSIPDLKVEIKTIKTTGDKILDVALSKIGDKGLF
TKEIEKELLDGEIDIAVHSMKDLPSELPPGLCIAAVLEREDPRDVLLSHKNYSLADLPQA
ALIGTSSLRRIAQLKAWRPDLQLVDMRGNVETRIRKMKEQDLDGIILACAGVKRLGLEEM
ISDYLPAHLVLPAVGQGMIAVEARSDEQDVLKLLSRINHQDSFLAGQAERGFLHELGGGC
QVPVASLAELQGGQLHIRGLIASLDGKEKYSGSSDCSPPEAEEAGRELARSLLQQGGAAI
LCETRK
>B2SMV3|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas oryzae pv. oryzae (strain PXO99A)|Swiss-Prot
MTTLRIATRKSPLALWQSEHVAAALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSFKDVPMELDDPFVLPAILERGDPADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLDER
ISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAALARWEGEGLFLQGMVGSASDGRLIHADAHGSADDTEDLGRRVAQGLFDKGAAQL
LAAL
>A6TJD5|hydroxymethylbilane synthase|EC 2.5.1.61|Alkaliphilus metalliredigens (strain QYMF)|Swiss-Prot
MRTIKIGSRASQLALVQAEIIINMLKEKFPQYTYEIIKITTLGDRILDKTLDKIGGKGLF
VKEIQKALAEEKIDLAIHSMKDMPGETPEELVLGAITKREDPRDVLITRENKSLEELPKG
AVIGSSSLRRQAQVMALRGDIKVVPIRGNVGTRLGKIETESLDGVILAAAGLNRLGLKEK
ISSYLEIEDFTPAVGQGALGCEARRKDIEMLEMLLAINHEETYRCVMAERAFLKLLEGGC
HVPIGAYGQQQGQELHMTGMVASSDGRRVIKEQVMGDIADFQALGIQLGETLIEKGAKEI
LETVNTDNRIVNTEGS
>Q7VRM4|hydroxymethylbilane synthase|EC 2.5.1.61|Blochmannia floridanus|Swiss-Prot
MQAKILRIATRKSPLAICQACYVCNKLKHYHPHIQTELIPIITTGDTSLHTVSKTNKIKK
GAFIKELEYALIEHRADIAVHSMKDVTVLLPKELIIPVLCKRHDPRDAFVSIQYPNIHSL
PTGSIIGTSSLRRQCQIRAQRSDLILHDLRGNINTRIKKLHQGQYNAIILAVAGLTRLKL
TKYIQTYIDPSELLPAMGQGVIAIECRINDINTISLLSPLYHKETSLCIKSERAVTTYLE
SYCRLPIASYAEIQNNQIWLRALIGLPDGSIIIRTEGIASLDKAEELGLNLAKDLLIQFK
KNTHFDINSIK
>B2JEN9|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia phymatum (strain DSM 17167 / STM815)|Swiss-Prot
MNSETLAPTPPATLVIASRESRLAMWQAEHVRCALHKLYPSCDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELENALADGRADLAVHSLKDVPMELPEGFVLSTIMEREDPRDAFVSNQ
YDSLAALPAGSVVGTSSLRREAMLRARYPELVVKPLRGNLDTRLGKLDRGDYAAIILAAA
GLKRLGLGERIRSLLDPADSLPAAGQGALGIEIRAGRDDLAAWLAPLHHEHTAAAVEAER
MVSRTLGGSCEVPLAAYATWHDGALHLRGIVATPDGERVLSAQASAPAATTDAALELGRE
VASQLEAQGALDIVRALSTASGPAASA
>B3QWI1|hydroxymethylbilane synthase|EC 2.5.1.61|Chloroherpeton thalassium (strain ATCC 35110 / GB-78)|Swiss-Prot
MKKALIIGTRSSPLALWQAEFIKAELSKHYPSLDISLRHIKTTGDKILDAPLAKIGDKGL
FTREIEHVMLRNEIDLAVHSLKDLPTETPEGLVITAITEREDNRDVLISKGKYTLKTLPQ
GAIVATSSLRRRSQLLHLRPDLEVIDMRGNLNTRFKRFEEGDAEAMLLAFAGVHRLEFSE
HIAEIISFDDILPAVGQGALGIETRIDDEETRELLKVLNHAETELCTKCERSLLRTLEGG
CQIPIGAHARIENGTFHFATYVGSIDGKRAIKKSLSRENVTTVEEAEQIGIEVADAARAA
GANEILCEIRTDNA
>B6J6K0|hydroxymethylbilane synthase|EC 2.5.1.61|Coxiella burnetii (strain CbuK_Q154)|Swiss-Prot
MIKKRSILIVTRKSPLALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGK
DLFVKDLQKALLNRDADIAVHSIKDMSACDGPELMVGAFIRREDPRDVLIVKGELSTLPP
HAVIGTSSPRRQCQLKKFQPGCKIKEIRGNVGTRLAKLDAGHYEAIVLAAAGLKRLGLEN
RIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAERAVNEKLGGD
CFTPIAAHAIIKNDQLSLFAMLGKIDGRVIIRATEIGNSEEAQRIGFKVASQLLEQGGDS
LLRELKQ
>C4ZZ69|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain K12 / MC4100 / BW2952)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q39QM7|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)|Swiss-Prot
MAPKQLRIGTRASQLALWQANWVKGELEKRYPGMAVELVKIKTMGDKILDVPLAQVGGKG
LFVKEIEEAMLRGEIDIAVHSMKDVPTEFPEGLGLYCITEREDPRDAVISRGVKFADLPQ
GARIGTSALRRQAQILKVRPDLQMVVIRGNVETRIRKLTDENLDAVILAAAGLNRLGFAD
QVSEYLPVELSLPAIGQGALGIECRLDDETIKDTIAFFNHPDTAHAVRAERALLWRCEGG
CQVPIAAHGQVSGDTLTLTGFVASVDGTRSVKDTISGPVTECEKLGIALAEKLLADGAHE
ILAEVYQREVAREKEIPV
>Q1INI6|hydroxymethylbilane synthase|EC 2.5.1.61|Koribacter versatilis (strain Ellin345)|Swiss-Prot
MATLRIGSRGSQLALWQANHISALLRERGHEVELEIIKTTGDKILDVALAKVGTKGMFTK
EIEEALAAGKVDVAVHSLKDLPTELPQGFELAAVTKRENPRDVFLSVKYDSISGLPQGAK
VGTSSLRRQAQIKAIRPDLEIFPLRGNVDTRVRKLEQGEYDAIILAFAGLNRLGKTQLVK
EIISEDVMCPAAGQGALGIEIRLGDTRMREILSFLNDYDARATTTAERALLNQLGGGCQV
PIGAFAEVKDGQVHLTAICARPDGSEILRESKSGADPAHLGEEVGKTLLARGATKILEDV
YSQNIAAPAQP
>Q2RJ26|hydroxymethylbilane synthase|EC 2.5.1.61|Moorella thermoacetica (strain ATCC 39073)|Swiss-Prot
MIEIKVGSRESELARWQARWVIQALEKAWPGLSCRLVTLKTKGDKILDVALARIGDKGLF
TKELELALLDGAIDLAVHSMKDMPTTLPEGLVIGAIGPREDPADVLVSPEGYTLATLPIK
ARVGTSSLRRKAQLAYARPDLELVDLRGNVPTRLAKMERDGLTAIVLAAAGLKRLNHGQV
LGEPIPYHICLPAVGQGAIGVEIRAGDRRVAELVAAINHPPTAAAVRAERAYLRALEGGC
QVPIAALATVEDTALVLQGMVASLDGREMLRDIASGSTRDPEAAGRELARKLLARGAGEI
LQEVKAQSGKYQG
>B3CUP9|hydroxymethylbilane synthase|EC 2.5.1.61|Orientia tsutsugamushi (strain Ikeda)|Swiss-Prot
MIIRVGSRASRLALIQAQAVVQKINDLLGLNAIIIPIKTTGDLIQNKNLYDIGGKGLFLK
EIEYALLNNTIDIAVHSLKDVPAYLPDGLQLAAVLERGNVGDMLVSKIANKITDLPLGAR
VGTSSVRRRIQLLRLRPDLNIVLFRGNVDTRWNKIFNNEVDATVLAAAGLQRLNYDTSRF
CNIISQDEMLPAIGQGVIAIEARKDDKLIMPLCAKINHQLTWQLIQVERGYLKTLNADCN
VPIGGLANYIGNNNFEAKFMLGDYNMRYFFYSEVCGKLQHGYDIGVEAAKNFQKKLFV
>Q46GS7|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain NATL2A)|Swiss-Prot
MTLDQLRIASRRSQLAMVQTNWVRDELQREHPDLVITIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLLGHAEIAVHSLKDLPTNLPDGLILGCITKREDPSDALVVNEKNQIHKLE
TLPEGSVVGTSSLRRLAQLRYHYPHLVFKDVRGNVITRLEKLDSGEYDCLILAAAGLQRL
GFANRIHQLIPTDISLHAVGQGALGIECVSGQQKVLDILKTLEHESTSKRCLAERSFLRE
LEGGCQVPIGVRTEINNNELILEGMVASLDGKRLIRDIKKGSVSSAEEIGIDLANELKGR
GAGEILEEIFKSARA
>A8GXC8|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia bellii (strain OSU 85-389)|Swiss-Prot
MINSIRIGTRKSKLALTQTNLVIEQIKQHFPNINCEIVEITTSGDLIQNKPLYDIGGKAL
FLKEIEQALLNKKVDLAVHSLKDVPGIIPKDLSIEAVLEREDSRDVFVCLTHKSIEELPK
NAVIGTSSVRRKLCVQRMRPDLEIIVFRGNVDSRINKLINKEVDATILAYAGLKRLNAFN
PEYCHLIEHSQMLPCIGQGVIAIEIRKDDHDMIEICKQINHLPTFELIKPERALLEYLDA
NCRTPIGAYSKYLDNGDIQTDFMLGNLDGSKIAFHTEISNPKTSKESGIKAAKVMLLSLS
>B0TJ54|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella halifaxensis (strain HAW-EB4)|Swiss-Prot
MSQNLIRIATRKSPLAMWQAEFVKAELEKIHEGLTVELLPMSTKGDIILDTPLAKVGGKG
LFVKELEVAMLEGKADIAVHSMKDVPVEFPEGLGLEVICEREDPRDAFVSNTYKTIEDLP
QGAVVGTSSLRRQCQIRAARPDLVIKDLRGNVGTRLAKLDAGNYDAIILAAAGLKRLKLE
ERIASFISAEQSLPANGQGAVGIECRTDDARVKALLAPLEHAETRMRVTAERAMNTRLEG
GCQVPIGAYAEIDGDTLSLRGLVGNPDGSQIITAASSGNKADAEKLGVALAEELLAKGAK
TILDAVYANA
>Q4L709|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus haemolyticus (strain JCSC1435)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFIDKLKAVDPTLEIEIKEIVTKGDRIVNKQLSKVGGKGLF
VKEIQQELFDKEIDMAIHSLKDVPSIIPEGLTLGCIPDREVPFDAYISKNHIPLNELPDG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLKKLEIEDYDAIILAAAGLRRMGWSDD
IVTTYLDKDILLPAIGQGALGIECRSDDVELLELLSKVHNQAVANCVTAERTFLSAMDGS
CQVPIGGYATNKENGEIEFTGLIMTPDGTKRYEHTEVGKNPVDLGEAVSRVLKEQGAYEI
IKKLNEEQAH
>Q5SLE8|hydroxymethylbilane synthase|EC 2.5.1.61|Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)|Swiss-Prot
MRVVVVGTRGSALALAQTRFVVERLKETWPETEFKIRTIKTRGDQGASPREEAIFVKEIQ
EALLSREIDIAVHSLKDLPTESPRGLKIASVPRRQDPRDVFLGKAAKRLKDLPPGAVVGT
SSVRRKAQILALRPDLVVRDLRGNVDTRLAALGNGEYDGIVLAAAGLIRLDLRNRIDEFL
DPGEVLPAPGQGALALEVREGDDLAEELCYALHHPPSYHRVRAERAFLRGLGAGCLAPVG
ALAHVEEDGTLRLEGVLLTPDGKSFIRAEIEGDVSEAEELGLDLARDVLEQGGREILAQI
R
>P28789|hydroxymethylbilane synthase|EC 2.5.1.61|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)|Swiss-Prot
MGPETLHIGGRKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTLGDQIQFKPLYSFGGKA
LWTKELEDHLYHDDPSKKLDLIVHSLKDMPTLLPEGFELGGITKRVDPTDCLVMPFYSAY
KSLDDLPDGGIVGTSSVRRSAQLKRKYPHLKFESVRGNIQTRLQKLDDPKSPYQCIILAS
AGLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGDTKMMKILDEICDLNATICCLSE
RALMRTLEGGCSVPIGVESKYNEETKKLLLKAIVVDVEGTEAVEDEIEMLIENVKEDSMA
CGKILAERMIADGAKKILDEINLDRIK
>A0LRF1|hydroxymethylbilane synthase|EC 2.5.1.61|Acidothermus cellulolyticus (strain ATCC 43068 / 11B)|Swiss-Prot
MTTAAALSVLRLGTRRSTLARAQTEEIAGALRAAGCRVEIVGIQSTGDRHADVPLHEFAG
SGVFVAELRAALLRGEVDVVVHSMKDLPTAEIPELAIAAIPRRADPRDALVTGAGCRLAE
LPTGAIVGTGSPRRAAQLRLLRPDLEIRPIRGNLDTRLGKLHAGGYAALIVAAAGLARLH
RSEEAAEFFDPTVMLPAPGQGALAVECRRADIADGGRLAGILAGLDDPATRAAVTAERAL
LAAVGAGCSAPVGALGVVTADTLQLDAVVVDPSGTTAFRRSLTGTPDDASDLGRRLAADL
IRAGADQLLQAPKQTGEPHDPDRHDKGTGRP
>Q633Y0|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus (strain ZK / E33L)|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDDE
VITEHLDETLCVPAVGQGALAIECREDDTDLLQLLAHINDAVTERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>B4E8C4|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia cepacia (strain J2315 / LMG 16656)|Swiss-Prot
MNSETPAAGPQQAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQ
ILDRTLSKVGGKGLFVKELEAALADGRADLAVHSLKDVPMALPDGFALAAIMEREDPRDA
FVSNDYASLDALPAGAVVGTSSLRREAMLRSRYPHLEVLPLRGNLDTRLAKLDRGDYAAI
ILAAAGLKRLGLEARIRALLDVEASPPAAGQGALGIEIAAHRDDVAAWLAPLHDPRTALA
VEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGKRVLTAEECGAVMTVADAL
ALGRAVSDELEAQGALDIVQALLAGSQAAGKGDA
>Q9ABZ8|hydroxymethylbilane synthase|EC 2.5.1.61|Caulobacter crescentus (strain ATCC 19089 / CB15)|Swiss-Prot
MSRQPPIRIGARGSKLSLAQSGLMQARIAHALGVPAGASKDEIEAAAPLIPIVTSGDRIQ
DRRLMEIGGKGLFTKEIEEALLDGRIDCAVHSLKDMPAELPPGLVLAATPEREDPRDAFI
SHVCERLEDLPKGARLGTASLRRQAQALHVRPDLEIVMLRGNVDTRLAKLERGEADAILL
AQSGLNRLGLGHLTRSWLDPDACPPAPGQGALVIETRAEDIGAPWLEAVRCRQTTIAVAA
ERGALLALEGSCRTAIGARAILDGARLSMIVEALTPDGAQRFRREGDITLTGADDIAEAR
AFGLTLGAEVRAAGGDAIILPE
>Q8XKG4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium perfringens (strain 13 / Type A)|Swiss-Prot
MELIIATRKSKLAQVQTEKVMELLKGKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVK
EIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGAR
IGTSSIRRAEQLKLFRDDLEIVPIRGNVQTRIKKITEENLDGIILAAAGLKRLGMEDVIS
DYFDPKVFLPAIGQGALGIECLKGGEFNDYFKALDSKEVRTTVEAERSFMKVLNGGCHSL
IGAYSEVKDNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILEEV
>A1VCX6|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio vulgaris subsp. vulgaris (strain DP4)|Swiss-Prot
MKHLVIATRGSKLALWQAEHIKSLIETEHAGKVDVSLKIIKTKGDIILDVPLAKVGGKGL
FVKEIEEALLDGSADLAVHSMKDVPMELPEGLFLGCIPEREEPSDTLLSVRYASLDALPH
GARVGTSSLRRQSQLLALRPDLDIISLRGNVDTRLRKLMDGEFDAIVMATAGLKRLGLSA
PHHEVLAPPRFLPAVGQGALGIEFREDRADLRDMLAFLDHRPTRIRVEAERGFLAGLEGG
CQVPIAGHAVMTGDDDFRIEGLVADLKGERVIRRTLEGTGANARNRGLELASQVLADGAA
EILDEVYASGAADRQ
>B2SE34|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. mediasiatica (strain FSC147)|Swiss-Prot
MKQITIASRESKLALWQTNFVKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>P56140|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain ATCC 700392 / 26695)|Swiss-Prot
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEKSAFCCRLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKQGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>Q12WM8|hydroxymethylbilane synthase|EC 2.5.1.61|Methanococcoides burtonii (strain DSM 6242)|Swiss-Prot
MILGTRGSALAIAQADLVTKMLEEKGHELTRNVIKTSGDVFTDRPLHEVAGVGVFVRELD
DRMIEGEVDIAVHSMKDLPTVRPPELAIAAVLKRDSPYDVLLTADGSTLDELPDGAIIGT
TSMRRRAQLLRYRPDLNVEDLRGNINTRIQKLKAGQYDGILLAEAGLQRMGWDMDVQRLP
AEAFCPSANQGTIVVVTRADDEAERACSVLNHERSRMETEVERLLITDVEGGCIVPIGSF
AQMNEDGDEIHVLVEVLAVDGTREIRIEDDIPVKNYREHALSIGRMLVEMGGKELVQEAV
CEMSGCDDE
>Q1QQP5|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrobacter hamburgensis (strain X14 / DSM 10229)|Swiss-Prot
MQSSGETDILATIGTRGSALALAQANEVRDRLARAHQVAPERIVIKTIRTSGDAIQDRPL
FDVGGKGLFTKEIEEALLAGSIDFAVHSSKDVPTFLPDATWLPAFLPREDVRDAFISPRA
ASLNDLPAGSIVGTASLRRQAMVLRLRPDLKVSVIRGNVETRLRKLVAGEADATLLALAG
LNRLGLQDRATRILETDEFLPAVGQGAIAIESRRDDDRINAFVKAIGDSETEVALSAERS
FLALLDGSCRTPIGGHCRVNGDRIHFRGLIISPDGTQSYETTREGARADAAALGADAARE
LRERAGEKFFTLFAGA
>A9BEB6|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus (strain MIT 9211)|Swiss-Prot
MVLDQLRIATRRSKLAMVQTHWVKEQLEKAHPGINISIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLIGRADIAVHSLKDLPTNLPEGLMLGCVTEREDPADALVVNKSLKDKQLH
ELPPGTILGTSSLRRLAQLRHHYPHLIFKDVRGNLITRLEKLDAGAYDCLILAAAGLTRL
GFGDRVHQLIPCEISLHAVGQGALGIECVENKPEVLEIIKSLEHEETSQRCLSERSFLRE
LEGGCQVPIGVNSQISGQDLILTGMVASLDGKKLIKDSKRGDKSNPELIGKELANELKSQ
GAMEILQEIFDSVRKD
>A1RQK2|hydroxymethylbilane synthase|EC 2.5.1.61|Pyrobaculum islandicum (strain DSM 4184 / JCM 9189)|Swiss-Prot
MKIRVATRGSKLSLIQTEELLAQIKAVEPDVQFEIVVVKTTGDLIQDKPLFQIGVKGIFE
KEVNLAVLRGEADMAVHSLKDLPSELTPGLVLAGFSKRAPPHDVLISRGGYTLETLPKGA
VVGTSSVRRAEFLKAVRPDVEVKPLRGNVDTRVGKVLSGQYDAAVMAAAGLQRLYGSSPP
VSIVPLRVEEVPPPPGQGIVVAVVKEEDSWLIDLLKKASDKTAAIEATAERAFLAGVGAG
CHVAIGGVAKLTPQGSLEFTAGYAAGGAKYVVKVFGEDPVEVGKRAAQLIAEVRQKFKQR
D
>P0A1Q9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella typhi|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>P64340|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain Mu50 / ATCC 700699)|Swiss-Prot
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q3AWQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain CC9902)|Swiss-Prot
MALTELRIASRRSQLAMVQTNWVKAELEKAHPGLTITVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGRADIAVHSLKDLPTNLPEGLMLGCITEREDPADALVLHAKNKHLNLA
TLPEGAVVGTSSLRRLAQLRHHYPHLEFKDVRGNVITRLEKLDSGAYDCLILAAAGLGRL
GFADRIDQSIPGDISLHAVGQGALGIECVENQPDVMEIIKVLEHGPTSQRCLAERAFLRE
LEGGCQVPIGVNTRFEGDQLILTGMVASLDGKRLIREQASGPSTDPESIGLELAATLKGL
GAGEILKEIFDAVRPEA
>Q8P536|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas campestris pv. campestris (strain ATCC 33913 / NCPPB 528 / LMG 568)|Swiss-Prot
MTTLRIATRKSPLALWQSEHVATALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDAPFVLPAILERGDPADALVSNLYATLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEAR
ITARLDAPEWLPAPAQGAVAVECRGDDARIHDLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAAFARWEGEDLFLQGMVGSASDGRLIHAEAHGSPDATEDLGRLVADGLFEKGAAQL
LAEL
>O29026|hydroxymethylbilane synthase|EC 2.5.1.61|Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)|Swiss-Prot
MKLIVGTRGSKLALAQTNKVAERLKERYEVEIRIVKTAGDIMKDKPLYEFKGMGAFVRAL
DTALAEGKVDVAVHSFKDVPSQRVEGTVVAAVIERDSPCDVLISRDGSTLEELDEGAVVG
TSSLRRRAQLSRLRGDLRFENLRGNLDTRLRKLREGNYDAIVVAEAGLKRLGLDREVEYQ
PFPPEVIVPPANQGIIAIATRKGEEDLVAFLNDEKTWLEAMVERAVIKELGVGCAVPVGV
YAEAQSRVRLICEILDKKYLRVEEKLSKDTAVEEAAEIGKDLRKEIYGG
>Q7VVU9|hydroxymethylbilane synthase|EC 2.5.1.61|Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)|Swiss-Prot
MAAVERLTIATRASRLALWQAEHVRDLLRARYPACSVELLTLTTRGDQILDRTLSKVGGK
GLFVKELETALLDGRADLAVHSLKDVPVDLHAPFELSCVLERADPRDAFVSNDYGSLADL
PPGAAVGTSSLRRESQIRARYPHLVVKPLRGNLDTRLGKLDNGDYAAIVLAAAGLERLGL
AARIRALLEPDDSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAERAVSRMLG
GSCQVPLAAYARIDGDELALRALVAAPDGRRIVRAERRGPRDQAQAIGESAARDLLADGA
DAILAELLPTSPAP
>A8MDU3|hydroxymethylbilane synthase|EC 2.5.1.61|Caldivirga maquilingensis (strain ATCC 700844 / DSMZ 13496 / JCM 10307 / IC-167)|Swiss-Prot
MIIRIATRGSALSLKQTKIVMDRILEFNKDVEFKLIIVKTTGDVDLSKPLYEIGVKGIFE
REVNQAVLRGEADVAVHSLKDMPAQISNDLTLVMTPPRDNPRDALVSLRQYTVDTLPLNS
IVGTSSLRRRGFLLSLRRDVTVKPIRGNVDTRIRKLNNGEYDALIMAAAGLERLSINANV
SEISPELMPPAPGQGIIGVVARRDRDDLIKVLRRSSDEETFKEAAAERAFLSRIGAGCHV
PLGGLALLDDGYFDFTYGVVDPDGVEKFINSTRIDARNPEEAGRVAAEDLLRNARGLVAR
LLKYS
>A7FSG8|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain ATCC 19397 / Type A)|Swiss-Prot
MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGVILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGISLAEHILKD
>A7MQJ1|hydroxymethylbilane synthase|EC 2.5.1.61|Cronobacter sakazakii (strain ATCC BAA-894)|Swiss-Prot
MLDNVLRIATRQSPLALWQAQYVKQRLEACHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELELAMLDGRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNQYKSLDEMP
AGSIVGTSSLRRQCQIAARRPDLIIRSLRGNVGTRLSKLDNGDYDAIILAVAGLKRLQLD
ARITSPLAPEISLPAVGQGAVGIECRLDDTRTRELLAPLNHEETAVRVRAERAMNTRLEG
GCQVPIGSYAELRDGELWLRALVGAPDGSRIVRGERRGAPEDARQLGISLAEELLNHGAR
EILADVYQGDGPA
>B6I4E0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain SE11)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A4IRG5|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus thermodenitrificans (strain NG80-2)|Swiss-Prot
MRNIVVGSRRSKLALTQTNWVINELKRLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLF
VKEIEHEMLTGGIDMAVHSMKDMPAVLPSGLVIGSVPRREDVRDVLVSKGNLSLSDLPSG
AVIGTSSLRRSAQLLAYRPDVTIKWIRGNIDTRLAKLKNEDYDAIVLAAAGLARMGWSDD
VISEYLSPDVCVPAVGQGALAVECREDDVELREWLSRLNDEQTERAVRAERAFLQQMEGG
CQVPIAGYAEVKEGMVHLTALVASPDGKEKYKEIVIGADPEEVGRQAAALLSEQGAKELI
ERVKKELGN
>Q5X1F2|hydroxymethylbilane synthase|EC 2.5.1.61|Legionella pneumophila (strain Paris)|Swiss-Prot
MSAKIIRIATRQSPLALWQANHVREMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKG
LFVKELEEALLDKRADLAVHSTKDMPAQLPDGLSLAAICKRDNPFDALISPRFKSLDALP
KNAIIGTSSLRRQSQLLAYNPNLQIKTLRGNIHTRLSKLESGEYQAIILAAAGLERMGLA
HHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIHGLNDPISALCVHTERRVNAKLGG
NCHIPFAVYCTITAEKLLLLRAKVLNLDGSQMIDDEQQGKIEEAEIIADRCTESLMTKGA
MSLLSTIPS
>A1KFY6|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium bovis (strain BCG / Pasteur 1173P2)|Swiss-Prot
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>Q43082|hydroxymethylbilane synthase|EC 2.5.1.61|Pisum sativum|Swiss-Prot
MEMTLYSSSSFSLPSAPSNPSLSLFTSSFRFSSFKTSPFSKCRIRASLAVEQQTQQNKTA
LIRIGTRGSPLALAQAHETRDKLMASHTELAEEGAIQIVIIKTTGDKILSQPLADIGGKG
LFTKEIDEALINGDIDIAVHSMKDVPTYLPEETILPCNLPREDVRDAFISLSAASLADLP
AGSVIGTASLRRKSQILHRYPSLTVQDNFRGNVQTRLRKLSEGVVKATLLALAGLKRLNM
TENVTSTLSIDDMLPAVAQGAIGIACRSNDDKMAEYLASLNHEETRLAISCERAFLTTLD
GSCRTPIAGYASRDKDGNCLFRGLVASPDGTRVLETSRIGSYTYEDMMKIGKDAGEELLS
RAGPGFFNS
>Q02EA3|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa (strain UCBPP-PA14)|Swiss-Prot
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHSDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAE
AILEAVYGEAGHP
>A8F1Y8|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia massiliae (strain Mtu5)|Swiss-Prot
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCKIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEAFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLKICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDADPRHLSKLAYRKAFEGNTEALATAAYKSDRTDASTGLTYKLPLEV
EFGKMSNIQTDFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>A8G0W4|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella sediminis (strain HAW-EB3)|Swiss-Prot
MSQNVIRIATRKSPLALWQAEFVKAELEKFHEGLTVELLPMSTKGDIILDTPLAKVGGKG
LFVKELEVAMLEDRADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNNYKNISELP
QGAVVGTSSLRRQCQIRASRPDLVIRDLRGNVGTRLGKLDAGNYDAIILAAAGLKRLKLE
ERITSFISAEESLPANGQGAVGIECRINDERVKALLAPLEHTETRHRVIAERAMNTHLEG
GCQVPIGAYAEIQDDTLTLRGLVGNPDGSHIIEATKVGSKTDAQAIGVALAEELLSKGAK
AILDAVYIK
>Q30S90|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251)|Swiss-Prot
MKKLVIATRGSQLALWQSNHIKAILQEQNPGLEVELNVIVTTGDRIQDKALSKIGGKGLF
LKELEEAMLQGEAQIAVHSLKDVPTVMPDGLILAAITEREDSRDALLSEKYANIDALPKN
AVVGTSSLRRRMQIQKLRPDLIIKDLRGNVDTRIRKLKEGEFDAIILAAAGINRLSLLDA
VKHVYPISLEEMVPSMGQGALGIEAVNDAEVLRIVAGLEDEYSRIETTIERSFVDELEGG
CQVPIGVNASVLDDGTISIRAVLGLPNGEEMLSDSKITSKKDYENIGREIAAEFIEKGAK
ELLSRAEAMMENK
>Q0W5T2|hydroxymethylbilane synthase|EC 2.5.1.61|Uncultured methanogenic archaeon RC-I|Swiss-Prot
MRIGTRGSKLALAQAEKVRRLLKEQGVEATITVIKTSGDVQKDSPLYMMKGYGAFVREID
DLLLKNEVDLAVHSLKDIPTVRPENLVTAAVLKRESALDVAVIRNAERLADLPEGAVVGT
SSTRRAAMIYRHYPGLVTKDIRGNVDTRLRKLRDGEYDAILLAEAGLIRLGLDLKVERLD
PYNFVPAANQGVIAIVARQGTPEAEVVKELNDETTWIETRVERIIAAGLDGGCVVPMGVY
ATRVGDEIDVIGEVLSLDGRQQVRVRETIPVAGCEEHAKQVSEKLVLAGGLKLAEEARKE
LDR
>Q0W5T2|hydroxymethylbilane synthase|EC 2.5.1.61|Uncultured methanogenic archaeon RC-I|Swiss-Prot
MRIGTRGSKLALAQAEKVRRLLKEQGVEATITVIKTSGDVQKDSPLYMMKGYGAFVREID
DLLLKNEVDLAVHSLKDIPTVRPENLVTAAVLKRESALDVAVIRNAERLADLPEGAVVGT
SSTRRAAMIYRHYPGLVTKDIRGNVDTRLRKLRDGEYDAILLAEAGLIRLGLDLKVERLD
PYNFVPAANQGVIAIVARQGTPEAEVVKELNDETTWIETRVERIIAAGLDGGCVVPMGVY
ATRVGDEIDVIGEVLSLDGRQQVRVRETIPVAGCEEHAKQVSEKLVLAGGLKLAEEARKE
LDR
>B2K065|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pseudotuberculosis serotype IB (strain PB1/+)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVAICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
TRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>O66621|hydroxymethylbilane synthase|EC 2.5.1.61|Aquifex aeolicus (strain VF5)|Swiss-Prot
MKIRIGTRKSKLALWQANYVKDFLEKHWGVEVELVKITTTGDKITDVPLAKIGGKGLFVK
EIEKALLEGSIDLAVHSLKDVPMVIPKGLKLGAITKRENPYDVLISRSGKKLYELPSGSV
IGTSSLRRQVQIKKRRRDLKVEVLRGNVDTRMRKLKEGLYDAVILAYAGVKRMGYESEIT
EVLEDFIPAVGQGSLAIEIREGDKRIEELIKPLNNEESFLCAIAERTFLRRLEGGCQVPV
GAFAKIENGTLKMKAFISDIEAERYIEGYREGNPEEAEKLGLSLAEELLKKGGEEILKEI
YSSQ
>Q7WKM1|hydroxymethylbilane synthase|EC 2.5.1.61|Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)|Swiss-Prot
MAAVERLTIATRASRLALWQAEHVRDLLRARYPACSVELLTLTTRGDQILDRTLSKVGGK
GLFVKELETALLDGRADLAVHSLKDVPVDLHAPFELSCVLERADPRDAFVSNDYGSLADL
PPGAAVGTSSLRRESQIRARYPHLVVKPLRGNLDTRLGKLDNGDYAAIVLAAAGLERLGL
AARIRALLEPADSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAERAVSRMLG
GSCQVPLAAYARIDGDELALRALVAAPDGRRIVRAERRGPRDQAQAIGESAARDLLADGA
DAILAELLPTSPAP
>Q63W73|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei (strain K96243)|Swiss-Prot
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>O84301|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis (strain D/UW-3/Cx)|Swiss-Prot
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>A9KDC4|hydroxymethylbilane synthase|EC 2.5.1.61|Coxiella burnetii (strain Dugway 5J108-111)|Swiss-Prot
MIKKRSILIVTRKSPLALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGK
DLFVKDLQKALLNRDADIAVHSIKDMSACDGPELMVGAFIRREDPRDVLIVKGELSTLPP
HAVIGTSSPRRQCQLKKFQPGCKIKEIRGNVGTRLAKLDAGHYEAIVLAAAGLKRLGLEN
RIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAERAVNEKLGGD
CFTPIAAHAIIKNDQLSLFAMLGKIDGRVIIRATEIGNSEEAQRIGFKVASQLLEQGGDS
LLRELKQ
>Q8FBP1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)|Swiss-Prot
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q747I1|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)|Swiss-Prot
MALNRLRIGTRASQLALWQANWVKSELEKRYPGMEVELVKIKTIGDKILDVPLAQVGGKG
LFVKEIEEAMLRGEIDIAVHSMKDVPTEFPEGLGLVCITEREDPRDAFISNGVTFANLPQ
GAKIGTSALRRQAQLLKVRPDLEMVIIRGNVETRIRKLTEDKLDAVILAAAGLKRLGFTD
VVTEYLPVDLSLPAIGQGALGLECRLDDQAVRETIDFFNHPDTAHAVRAERALLWRCEGG
CQVPIAAHGQVSGDSLTLTGFIASVDGTRSVKESISGPVTDCEKLGIALAEKLLADGGHE
ILAEVYQREVSREKEIPV
>B2G9H4|hydroxymethylbilane synthase|EC 2.5.1.61|Lactobacillus reuteri (strain JCM 1112)|Swiss-Prot
MTNKVIVGSRKSKLAMAQTELVIASLEKIFPDIKFEIKNVITEGDRNRHVSLAKIGGKGV
FVKEIEDELKDGTIDFAVHSLKDVMPILPEELVLGAFPKRVSPYDCLVSRKNLSSLNDLP
KGARIGTNSLRRQGQLLSIRPDLKIIPIRGNIDTRLRKIDTEALDGIILAEAGLTRLNID
LSSYHVLDLQNYIMPAVGQGCLAIECRKNDTRIRKMLDQINDEESAYCVQVEREFMRELG
GSCNFPIGGHAYAKNGQILFDGLIASPNGEHVIKETKIPANNSGVGKKVADQLLAKDKFG
IIEGE
>A0QLI0|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium avium (strain 104)|Swiss-Prot
MIRIGTRGSLLATTQAGGVRDALIARGHPAELVTITTAGDRSSGPIESLGVGVFTTALRE
AIEEGRVDAAVHSHKDLPTADDPRFAVAAIPARNDPRDAVVARDGLVLGELPPGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLGDVTETLE
PVQMLPAPAQGALAVECRAGDSRLAAVLAELDDADTRASVTAERALLAELEAGCSAPVGA
IAEVVESIDEDGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFELGA
RELMSGARHDPARGN
>O69110|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus macerans|Swiss-Prot
MTKRTIVVGTRQSQLALTQTEQVIGDLKELCRAHGLPFEFEIKKIVTKGDRILDVTLSKI
GGKGLFVKEIEQAMLDGEIDMAVHSMKDMPSVLPEGLINGGVPLRKDPRDALISRSGLHL
HELPQGARVGTSTLRRSSQLLAYRPDLVLEPVRGNIDSRLRKLEEEGFDAIILAAAGLQR
MGWENRVTAYLSADVCLPAVGQGALGIECRENDAELRDVLSLYNDPDTALTVAAERRFLA
VLNGGCQVPIAAYANLERAGGQAPEEGGRAAASQAPAALRIRLTGMVGSADGRGYFEGEC
RREDPVAFGERIAGLLLAQGGRVT
>Q15Z15|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)|Swiss-Prot
MSDRVIRIATRKSALAMWQAEYVQAKLLEAHPQLKVELVPMSTQGDRILDTPLAKIGGKG
LFIKELEVAMSEGRADIAVHSMKDVPVDFPAGFGLHCICERENPYDAFVSNTYASIEELP
QGAIVGTSSLRRQCQIRSARPDLTIRDLRGNVNTRLAKLDDGQYDAIILAAAGLIRLEMQ
DRIKTYIEPTVSLPAVGQGAVGIECRNDDAELIELLKPLNHSDTESRVKAERAMNAKLNG
GCQVPIGSYAVLNGDELYLRGLVGSPDGSVLLQAEKRGNVNDALSIGVDVAEQLLEKGAG
DILQALYKD
>A8EYJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia canadensis (strain McKiel)|Swiss-Prot
MTHSIRIGTRKSPLALIQTNLVIQQIKQFVPDINYKIVPITTSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEDLIIAAVLEREDPRDVFVCLKYKSIEELPQ
NAIIGSSAVRRKTFIEKIRSDLKVTVFRGNVDSRIKKLMNGEVDATILAYAGLKRLNAFN
PQYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLETCNQINHLTTFELIKPERAFLEYLDA
NCRTPIAAYSKYLDKDNIETDFMLGNLESSKITFHTETTNIKTSKEAGIKAAKIMLSELE
R
>A8GZG4|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)|Swiss-Prot
MSQNLIRIATRKSPLAMWQAEFVKAELEKIHEGLTVELLPMSTKGDIILDTPLAKVGGKG
LFVKELEVAMLEGLADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNTYKTIEDLP
QGAVVGTSSLRRQCQIRAARPDLVIKDLRGNVGTRLAKLDAGNYDAIILAAAGLKRLKLE
ERIASFISAEQSLPANGQGAVGIECRTDDARVKALLAPLEHAETRMRVTAERAMNTRLEG
GCQVPIGAYAEIDGDTLSLRGLVGNPDGSQIITASSSGSTADAEKLGVALAEELLSKGAK
TILDAVYANA
>B4SJT8|hydroxymethylbilane synthase|EC 2.5.1.61|Stenotrophomonas maltophilia (strain R551-3)|Swiss-Prot
METVRIATRKSPLALWQSEHVADRLRQAHPGLHVELVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDEPFALPAMLTRHDPADGFVSNLYASLDALPIG
ARVGTSSLRRQAQLRALRPDLQLLDLRGNVNTRLAKLDNGGYDAIVLAVAGLERLGLGER
IVARLQPPQWLPAPAQGAVAVECDGSNARLMALFAGLDDAATRACVEAERAMNRALHGSC
HVPVAAIAQWQGQDLHLQGLVGSASDGRAVRAEAVGPASDPEVLGQRVAKMLLDAGAGEL
LNV
>Q31JG5|hydroxymethylbilane synthase|EC 2.5.1.61|Thiomicrospira crunogena (strain XCL-2)|Swiss-Prot
MKKTLRIATRKSPLAMWQAEFVKAELEKHHEGLTVELLPMSTKGDKILDVPLAKIGGKGL
FTKELEDRMLAGEADIAVHSMKDVPMVLPEGFALGAILERHEPTDAFVSNDYAHFEELPQ
GAVLGTSSLRRKAQLMAARPDLVVKDLRGNVGTRLGKLDAGDYDAIVLATSGLKRLELDE
RIRHELSPETCLPAVSQGTLGIEYFEKDPEVLELIQVLNHRDTEIRTLAERAMNHRLEGG
CQVPIGVYAELEDDQIYLRGLVGALDGSEILRSEARGSQKDPETLGVYVAEQLLEQGAGE
ILKEVYDQA
>P30527|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia intermedia|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPVAFPEGLGLVTICEPDDPRDAFVSPHFAHIDDLP
AGSIVGNSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYHAIILAVAGLNRLGLA
SRI
>Q81LC7|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus anthracis|Swiss-Prot
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>A9M8M2|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella canis (strain ATCC 23365 / NCTC 10854)|Swiss-Prot
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>A8FKW8|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828)|Swiss-Prot
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPRGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>C1FVB9|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain Kyoto / Type A2)|Swiss-Prot
MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGISLAEHILKD
>Q9RRY0|hydroxymethylbilane synthase|EC 2.5.1.61|Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)|Swiss-Prot
MRTVTVGTRGSTLALAQTRWVVARLKEEWPETDFRIQTISTKGDRNRESLEQLAQKGDKG
FWVKEIEEALLAKKIDIAVHSLKDLPTEQPEGLEISSIPKRVDGRDALIGREGMKKLAEL
PEGARIGTSSVRRKAFLRAYRPDLIVKDLRGNIDTRLAALGSGEYDAIILAAAGLIRTEQ
RHRIDEFVDPDILLPAPGQGALALETRTEDDLTIEVAYAIHDHATDDRITAEREFLAGLG
AGCMAPVGAHAVIKNGLLTLEGWVGALDGTQVIRATSQGDVAECADIGAELAADMLERGA
AELIEAVRE
>B2VG55|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia tasmaniensis (strain DSM 17950 / Et1/99)|Swiss-Prot
MSDKILRIATRRSPLALWQAEYVQRRLIACHPGLRVELLPMVTRGDVILDTPLAKVGGKG
LFVKELEQAMLSGSADIAVHSMKDVPVAFPPGLGLVAICEREDPHDAFVSHHYTSVDSLP
QGAIVGTSSLRRQCQLSARRPDLVIRSLRGNVGTRLGKLDAGEYDAIILAVAGLKRLGLG
DRIRQVMPAEESLPAVGQGAVGIECRLDDIQTIALLAALNHSETACRVSAERAMNTRLEG
GCQVPIGSYALLEDDQLWLRGLVGSPDGNEMVRGERRGPRADAEKMGISLAEELLENGAR
DILAAVYQGNPPA
>A1WVT9|hydroxymethylbilane synthase|EC 2.5.1.61|Halorhodospira halophila (strain DSM 244 / SL1)|Swiss-Prot
MAAESLRIATRRSQLAMWQAEHIAAELQRLHPGLEVELVPMSTRGDEILDQPLARIGGKG
LFMKELEDGMLRGEADLAVHSMKDIPWRLPEGFDLAAVSDRADPRDAFVSNHYSDLDELP
HGARVGTASLRRQCQIMDRRPDLQIEVLRGNVQTRLRKLDDGVYDAIILAASGLDRLELT
HRIAGRLTPEQSLPAVGQGALGIECREGDERVMKLVEGLNHEATRIRINAERGMNARLEG
SCQVPIGGYAELDGDEVHLRGLVGAIDGSEVIRGEIRGPAAEAENLGRQLGDDLLARGAD
RILKAVAEQQ
>Q71ZB2|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 4b (strain F2365)|Swiss-Prot
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEVIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNRVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEVVHFKGLVGNADGSIILASEQAGANPSEIGNKVAEDLLSEGAD
TIIKELRNI
>A5TZP0|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)|Swiss-Prot
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>A5D3L5|hydroxymethylbilane synthase|EC 2.5.1.61|Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)|Swiss-Prot
MKREIAVGTRVSKLAMWQARWVVDRLKELCPGCSFRIVGIRTLGDRILDAALVKIGDKGL
FTKELEAAMLRGEIDMAVHSMKDLPTELPEGLVIGAVCKREHPADVLVSRRGKKLDELPG
GALVGTSSLRRCAQLLWYRDDLRMVNLRGNINTRLRKLEEENLDAAVLAYAGLFRMGRQD
AITQVIPFDICLPAVGQGSIGVEVRSDDGEVLELVKKIDHRESRLAVFAERAFLRRLEGG
CQVPVGALGTVENDRLRLEGVVATPDGKQLVRSFVEGNGGDAAAIGLRLAEKLLELGAGE
ILKRARQEERRE
>Q3K4T0|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas fluorescens (strain Pf0-1)|Swiss-Prot
MSSREIRIATRKSALALWQAEYVKARLEAAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTYSSLDALP
AGSIVGTSSLRRQAQLLTRRPDLEIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSADTEIHALLAPLHHADTADRVTAERALNKHLNG
GCQVPIACYAVLEGDQLWLRGLVGEPSGGKLLNAQARAPRAAAETLGVQVAEDLLSQGAD
DILKAVYGEAGHE
>A7NKU8|hydroxymethylbilane synthase|EC 2.5.1.61|Roseiflexus castenholzii (strain DSM 13941 / HLO8)|Swiss-Prot
MRNSLTIGTRASKLALVQTHMIRDALQAAHPGLTVAVERITTRGDIILDRPLNAIGDKGL
FVVEIEEAMRAGRVDLAVHSAKDLPSTLPPDMTLAVCPRRADPRDALVAQPGMTLASLPH
GARVGTSSLRRACQLRALRPDLTLLDLRGNVDTRLRKLREGQYDAIVLAAAGLKRLGLEE
VITELLEPDVLIPAVGQGIIGVEARAGDDEVLRLLAPLDDPAARAAITAERAFLARIGGG
CRVPVGALALLEGDELLLYGMIGALDGRMVRGMRSGSASDPAGLGSALAEELLDAGGQAL
LAG
>A9FDP9|hydroxymethylbilane synthase|EC 2.5.1.61|Sorangium cellulosum (strain So ce56)|Swiss-Prot
MPTELTLATRRSALALAQSRAFARSLEAAVPDLSLRELEVVTSGDKTQDRSLQDIGGKGL
FIKELEEALLDRRADFAVHSIKDVPAEIAPALCLACIPAREDPRDALVTRSGALLAELPA
GARVGTSSLRRAVALREARPDLVIEPVRGNVDTRLRKVFDGVFDAVVLALAGLKRLGLEA
RATEVLSPEVSLPAIGQGALGIECRTADDSVRDVLGTLADAETTICVSAERAVMAAVEGS
CRTPVAAYAVRDGGALWLRALLAEPDGSRLRRAERRLSWPGNTREAERLGADLGAELKKG
>C3N841|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)|Swiss-Prot
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIIDIKTKADLFSTDPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLERDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNEDIIP
>Q87KI9|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)|Swiss-Prot
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSNINEL
PQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EDRIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEVRGHRKDGEALGIQLANELLDSGA
RDILTKLYADHD
>B1JPE6|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pseudotuberculosis serotype O:3 (strain YPIII)|Swiss-Prot
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYTHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDGHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>D1JID7|hydroxymethylbilane synthase|EC 2.5.1.61|uncultured archaeon|TrEMBL
MIVGTRGSNLALVQTKKVCERLSELGVECEIKTVQSLGDVMTDRGLYEMPTIGVFVKKLD
MMLLDAKIDIAVHSMKDMPSEREEELDTSAVLPRDSPYDALVSRYRLDDMPEGAVIGTSS
VRRRYQFLNYVGERGVKVTIKDIRGNVDTRIAKFRRGEYDSVILAEAGFERLKLDIEYER
LDRDPFVPSPRQGIIAVVARRGSKESEILKQIDDSETRIEAEVEEEVLKVIGGGCSLPVG
VHATAKGGSVELAVYVAASDVRYKLEKVVLGKDYYMEETRELAQKFKSYL
>D0YU32|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus mulieris 28-1|TrEMBL
MHMIGSAQRPLVIGTRGSKLALTQTRMVAADLEQRGLAVRIETFVTEGDTNRASLSSLGG
VGVFAAALRVALLEGRCDLVVHSLKDLPTVEVPGLVVAAIPARVDPADVLVARDGLRLAD
LPAAARVGTGSPRRARQLAAARPDLSLVDIRGNVPTRIGRVRGLGTRAEQIGLDQGRAKE
DLDAVVLARAGLRRLGVEDVATDDLSETILPAGGQGALALETVADGLAAEEGRILAQTLR
IVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGQLTWENNATELLAGVLELRARVVGDNG
ESVEVSGETTVLLGTDADQRDFALAAAEQLGVDLATELLANGAGEMANLQATKESGTTQS
>D0YU32|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus mulieris 28-1|TrEMBL
MHMIGSAQRPLVIGTRGSKLALTQTRMVAADLEQRGLAVRIETFVTEGDTNRASLSSLGG
VGVFAAALRVALLEGRCDLVVHSLKDLPTVEVPGLVVAAIPARVDPADVLVARDGLRLAD
LPAAARVGTGSPRRARQLAAARPDLSLVDIRGNVPTRIGRVRGLGTRAEQIGLDQGRAKE
DLDAVVLARAGLRRLGVEDVATDDLSETILPAGGQGALALETVADGLAAEEGRILAQTLR
IVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGQLTWENNATELLAGVLELRARVVGDNG
ESVEVSGETTVLLGTDADQRDFALAAAEQLGVDLATELLANGAGEMANLQATKESGTTQS
>D1U0N2|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis KIM D27|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>C7MH04|hydroxymethylbilane synthase|EC 2.5.1.61|Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860)|TrEMBL
MTGASLRIGTRASDLALTQSGHVGAALVDGTGHEVELVHVSTRGDRDRTSPLAQIGGTGV
FVTAVRQALLDGTVDVVVHSCKDLPTAPLEEITLACYPPREDPRDALCARDGLTLAQLPA
GSRVGTGSPRRAAQLLRARPDLEVTGIRGNVETRLKRALGPEADLDAVVLAASGLRRVGR
EAVISELLPVEVMLPAPAQGALAVEATTAALAQEPWFAERLTAVDDPATRAAVTAERMLL
RTLEAGCSAPVAAYAEIEAPGAATAEGEPAGGGVLRLRALAIRTDGSHVVEGEARMALDL
AADALSGPESVPAALGAELAADLLSRGAGDILAEARS
>G0QW27|hydroxymethylbilane synthase|EC 2.5.1.61|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MEKMKGITFDIRRKLWPIFCQQQDIYSKSFNILRAYAQYDKEVGYIQGMSFIVKAILMHL
HPENDKEFPDIYFLDSTYERIAFWIFYYIMYEKQWRVLFLDGQPGLYEILNKFKKKMEQN
LSKIHEHIIGFEVLDMLLTIKELNLKKENFQLVQVSNAEGDYNLKDPLYQIGGVGLFTKQ
VENELINNNADIAVHSLKDLPTIIDEKLYIGAVPHLKKRSDIVIISEKNSEKTLQTLPEG
SIIGTSSLRRVNSLKYRFPHLKFENIRGNLNTRLNKLKTGQYNAIILAYAGVERLGWTDK
ITQVLDEKEYFYAPGQAALGIQCRKDDILSIKMLQYINNREAQIRVEAERQFLNSLEGGC
KLPIAVYSELNGEKLLLKGQVWDNNATYTIKDGFFYLNLFYFVFFKRNRRKYQ
>C4IK26|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium butyricum E4 str. BoNT E BL5262|TrEMBL
MDKLILATRKSRLAQVQTEIVMDSLKNKINKESEKLLIVTEGDRKLDVSLNKIGGKGLFV
KDIECALLEGSADAAVHSMKDVPYELSNEFEITAIIEREDIRDVLISKDGISFSKLRYGA
KIGTSSIRRAAQLKLLRSDIEVVPIRGNVQTRLAKMESENLDGIILAAAGIHRLKLDSII
TEYFDPKEFIPAVSQGAIGIECVKNSENSKYFKMLDNSEARITVEAERSFMRELKGDCHS
LIGAYSEVTGDELYMIGIYDLNGVIVRKDIKGKKSNHLEVGRKLAEKILNEK
>H7WEG7|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli H8|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKILKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>A8CBH8|hydroxymethylbilane synthase|EC 2.5.1.61|Plasmodium falciparum|TrEMBL
MHLLSFLSFIIWFIHCTAKRHEYSIKKYFLNSHNFCKIKPDPFRKDTLKKRLYSSDGIKD
EIIIGTRDSPLALKQSEKVRKKIMSYFKKMNKNINVTFKYIKTTGDNILDSKSVGLYGGK
GIFTKELDEQLINGNVDLCVHSLKDVPILLPNNIELSCFLKRDTINDAFLSIKYKSINDM
NTVKSVSKTEDIHHINKKDSDHNNDTLCTIGTSSLRRRSQIKNRYKNIYVNNIRGNINTR
IEKLYNGEVDALIIAMCGIERLIKKANLKHLLKNKEQKNICQPFLLKCNNKKCIDLCHVN
IQKLNKNLIYPALGQGIIAVTSHKKNYFISSLLKNINNKKSEMMAQIERSFLYHIDGNCM
MPIGGYTNMRNEDIYLHVIINDIHGYNKYQVTQKDTLYNYKEIGPNAAIKMKEIIGTEQF
NKIKAEAELHLLNNK
>B0K2L4|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoanaerobacter sp. (strain X514)|TrEMBL
MKKVIKVGTRSSELALKQTAMVINEIKKFRQDFEFEIVKITTQGDALIDKPVSEIGGKGV
FVKEIESALLKGEIDMAVHSMKDMPYEIPKGLKLMAVLKREDPKDVFVSGDGTQFMDLKE
GAKIGTSSLRRQVQLKALKPDIQIVPIRGNVRTRLKKMEELNLDGIVLSAAGLHRLGLEN
IITEYFPPDVVVPAPCQGILAVEIAESFDNIFQEFYPYIVDRKTFFEASVERELLKAFGV
NCRQPFGAYAQYRKEEDEEKINIKVAYQKENKLLKSEVTGLIEETDKMIEKLIEEFGGI
>H6PPE1|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia rickettsii str. Arizona|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>F8CEM1|hydroxymethylbilane synthase|EC 2.5.1.61|Myxococcus fulvus (strain ATCC BAA-855 / HW-1)|TrEMBL
MPHVRIATRQSPLALWQARHVGALLTSRHPGLEVSLVELTTEGDRFLSAPLSAVGGKGLF
VKEIEQALLDGRADLAVHSLKDMTSVFPEGLMLAAVPEREDPRDAFCGLGGLTLDTLPQG
ARVGTSSLRRSCILRSRRPDVDIVSVRGNVQTRLARTREQGLAGALLAYAGLKRLGLEDV
ITQVLPPEVSLPAVGQGVLAIQCRTEDARVRELLAPLEHATTRIAVTAERALLAKLEGGC
TVPLAGHATVSGDSVWLRGLVGRPDGTHVVRGEVRGPVSQAHALGEALADDLLSRGAADI
LRDFARRAEARES
>D2PE26|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain L.D.8.5 / Lassen #2)|TrEMBL
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIIDIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLERDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNEDIIP
>D6YPQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar E (strain E/11023)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVISITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>D3RZK1|hydroxymethylbilane synthase|EC 2.5.1.61|Ferroglobus placidus (strain DSM 10642 / AEDII12DO)|TrEMBL
MSERVVIGSRGSKLALAQAEKVKKLLEERDFEVEVKVIKTHGDIMKDKPLHEFKGMGAFV
RAIDEALKRGEIDLAVHSYKDVPSQRVEGTVIAAVLERESACDAFISREGLKFEEMPVAS
KIGTSSLRRRAFVKKLRKDLEVENLRGNLDTRLRKLREGFYDGIIVAEAGLIRLGLDKEI
EYERLNPEVFVPSANQGVIAVASRENEAELFSFLNHEKTRLETDVERAVLRELGIGCAIP
AGIYAKAEGKVRLIVEILSEEGEKSVRVDEKLSKENAVEEAVEIAKNLKSFI
>F0AII5|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis M0579|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVILQADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>B9S2Z0|hydroxymethylbilane synthase|EC 2.5.1.61|Ricinus communis|TrEMBL
MDTLSSISTMQGLMVPRPAAVSVSVLGSSLPQFKSPNCIKKQSLRITRASVAVEQQTQDP
KVALIRIGTRGSPLALAQAHETRDKLMAKHSELAEEGAIQIVIIKTTGDKILTQPLADIG
GKGLFTKEIDEALINGEIDIAVHSMKDVPTYLPEKTILPCNLPREDVRDAFISLSASSLA
ELPSGSVIGTASLRRKSQILHRYPSLSVLENFRGNVQTRLRKLNEGVVQATLLALAGLKR
LNMTENVTSVLSIDDMLPAVAQGAIGIACRSNDDKMANYLASLNHEETRLAVACERAFLE
TLDGSCRTPIAGYASKDENGDCIFKGLVASPDGTRVLETSRKGPYALDDMIMMGKDAGKE
LLLQAGPGFFDS
>H4DTA7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIGC348|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>B0BPU9|hydroxymethylbilane synthase|EC 2.5.1.61|Actinobacillus pleuropneumoniae serotype 3 (strain JL03)|TrEMBL
MMNLPMKDTLRIATRQSPLALWQANFVKDELEKRFPELSVELVTMVTKGDVILDTPLAKI
GGKGLFVKELELALLENRADIAVHSMKDVPMTFPEGLGLAVICEREDPRDAFVSNKYQNL
DELPAGAVVGTSSLRRQCQLMAKYPHLEVKSLRGNVGTRLSKLDNGEYDAIILASAGLIR
LGMPERIRSFISVEQSLPAAGQGAVGIETRVDDERVLNYLATLNHNPTACCVIAERAMNT
RLQGGCQVPIGGFATLNGNEITLNALVGALDGSNIIRASGVADRENAEQLGISVAEQLLA
QGADKILAEVYKDE
>E8UXJ8|hydroxymethylbilane synthase|EC 2.5.1.61|Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4)|TrEMBL
MHLRLGSRGSQLALWQANHIAASLRGAGHTTKITIIRTTGDRMQDPAYVKENPVTPEMDA
KGIFIKEIEEALLRGEIDLAVHSLKDLPTVMDPRFTLAAIPTRADARDALLSPEWVQLHT
LPDGARVGTTSPRRKAQMLAHRPDLQFVEIRGNIDTRLRKLAAGQCDALVLACAGIDRLG
ARLLHPVDLDPAHPEHGRAPHVECVTHADHDHLEEHPTEHEPAGQVDWIRERFAADTMCP
APGQGALGVETLSDAPEVIAAVSALDDAETRYAVEAERWMLHALGGGCSLPVGAWCVDKR
LTANVTAADGDEMLSSEISANEGESARSLGERVAADLVARGARELLQAYA
>I3XE03|hydroxymethylbilane synthase|EC 2.5.1.61|Sinorhizobium fredii USDA 257|TrEMBL
MVLSLNRFRFKERCSNNGWPGMQTKPFRIGTRGSPLALAQTHETRDRLAAAHGLPPEMFE
VVVLSTKGDRITDRPLAEIGGKGLFTEELEQQLLSGDLDFAVHSSKDMPTKLPDGLFLSA
FLPREDIRDAFIGGTAPRLVQLPEGATVGSSSLRRQALIRRLRPDINVITYRGQVETRLR
KLAEGQVDGTLLAYAGLRRLGMTDVPTELLDPKEFPPAPAQGAICIESRVGDNRVNALLA
AIDDPRTHEAVACERGFLATLDGSCRTPIAGYAQSDGTHIRFSGMILTPDGTTCHRIEID
GKAADATELGRRAGEEIRAKAGPGFFSSWA
>B1ERF1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia albertii TW07627|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMTSHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRTALPPEVSLPAVGQGAVGIECRLNDTRTRELLAALNHNETALRVTAERAMNTRLEG
GCQVPIGSYAELVDGEIWLRALVGAPDGSQIIRGERRGSPQDAEQMGISLAEELLNNGAR
EILAEVYNGDVPA
>C6SGN9|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis alpha275|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>H2BT09|hydroxymethylbilane synthase|EC 2.5.1.61|Gillisia limnaea DSM 15749|TrEMBL
MNKTIRIGTRDSELALWQAKTVQSALETLGHKTNLVPVKSTGDLNLDQPLYEMGITGIFT
KTLDIAMLTDKIDIAVHSMKDVPTALPKGIVEAAILKRANSKDILVHKGLDFLESKGTIA
TGSLRRKAQWLNKYPQHAVVDLRGNVNTRMKKLEENSWDGAIFAAAGLERINLTPENYLT
LDWMIPAPAQGAMLVVAKEKDEFCRKTLSALNHKESEICVHTEREFLKTLEGGCTAPIGA
LAEIRDGILYFKGGLYSLDGTQKFEIERVVSANQTQGFGKKCAEEILKNGGSELMKKIRE
VLK
>Q4MS69|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus G9241|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGITEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLINQGAKEL
ILAANKGQQ
>H5CU27|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC9D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C8WDJ7|hydroxymethylbilane synthase|EC 2.5.1.61|Zymomonas mobilis subsp. mobilis (strain NCIB 11163)|TrEMBL
MQLPFRLGSRGSPLALIQARSVASALCAAHSWSEDAVVIVPIRTSGDKNRHQALADIGGK
ALWTKELDIALTTGQIDAAVHSMKDVETFRPSHISIAAMLPREDVHDRLIGIPSLEVLPY
SGCVGTASPRRAAQIRRIRPDIEIKLLRGNIDTRLEKLANKQFDATLLAAAGLIRLGRND
VGYDVPLDQMLPAAGQGAIGIEALADSAAWEKVSIIDHYPTHLAVQSERQLLLRLNADCH
SPIAVFAEILEKNIRLRACLYTENGKFSASIDKEISQPSDAFEVGSLLLNQSPPEVQALF
LPRVLSER
>B8J0B3|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)|TrEMBL
MRNTLTIATRGSRLALWQAEHVKSCLQAIRPGLEIRLNVIKTKGDIILDVPLAKVGGKGL
FVKEIEEALLNGEADLAVHSMKDVPMELPEGLILGCVPPREDPTDCLLSHKYDSVAALPP
NACVGTSSLRRQSQLLAQRPDLRIESLRGNVDTRLRKLQEGMYDAIILASAGLKRLGLSA
PHMHALDPHTFLPAVGQGALGIECRENDYELFTLLAEMEDSATRVCVEAERGFLAGLEGG
CQVPIAGHARLLDDDTLRLEGLVAEVDGSRILRCSKDGHTSQARRWGLELAGEILEQGGK
GILEKLYRQS
>F9TUN3|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio nigripulchritudo ATCC 27043|TrEMBL
MSERAPIRIATRKSPLALWQANFVKDALQAAHPGLNVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYANIDAL
PQGAIVGTCSLRRQCQLKEYRPDLQIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIQSFIEPEQSLPAVGQGAVGIECRLDDEELIKLLEPLNHKATADRVSAERAMNLTLE
GGCQVPIGSYSLIEDGKIWLRALVGEPDGSKIVRGEIKGPVDKASELGVTLAHQLLDDGA
KEILERLYQDHE
>H0CEG8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21331|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDDELLSLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVEIGKTVSNKLKEQGAYEI
IKRLNEQH
>H8N9I1|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia prowazekii str. BuV67-CWPP|TrEMBL
MINSIRIGTRNSTLALIQTNLVIEQIKQIFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGKIPVELVIAAVLEREDPRDVLVCLNYQSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDAIILSYAGLKRLNVFN
QKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPERAFLEYLDA
NCSTPIAAYAQYLDAYNIQIDFMLGNLDCTKIIFQTEITNIKTSKICGIKAAKMMLAQQ
>H8L266|hydroxymethylbilane synthase|EC 2.5.1.61|Frateuria aurantia (strain ATCC 33424 / DSM 6220 / NBRC 3245 / NCIMB 13370)|TrEMBL
MRDNTAATASTIQADPARSLSSLKDIMTIPKLLRIATRKSLLALWQAEHVAALLRERYPQ
TQVELVPLSTRGDEILDRSLAAIGGKGLFLKELEVAMLEGRADLAVHSLKDMPVELDPGF
ALAAVLPRADAADAFVSFHHASLQALPQGARVGTSSLRRQALLRSLRPDLQINDLRGNVI
TRLAKLEEGQYDAIILACAGLERLELGQHIRQRLHAPDWLPAPGQAAIGIEALSAADDVL
AGLAALDDAPTRRQVTAERAMNQALGGSCSVPVGAWCEQIDADWLVLSGLVGDIAGGQLI
QASQHGEAAQPEVLGRAVAEQLLAQGAAAFLS
>H4HGW5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1096|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E6JMS1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis FRI909|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSIIPDGLTLGCIPDREIPFDAYIAKNHIPLEELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDVLLPAIGQGALGIECRSDDKELLDLLTKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIVQDNQIEFTGLIMSPDGKERYEHTTLGSDPVQLGIEVSQVLKKQGAYDI
IKKLNEAE
>H4UAA3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC5E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F0EQK4|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus parainfluenzae ATCC 33392|TrEMBL
MAVLKTLKIATRQSPLALWQANFVKDQLEKFHPTLSVELVPMVTKGDVILDSPLAKIGGK
GLFVKELENALLEKRADIAVHSMKDVPMEFPEGLGLSVICKREDPRDAFVSNTYRSLDDL
PQGAIVGTSSLRRQCQLKQLRPDLDIRSLRGNVGTRLSKLDNGEYDAIILASAGLIRLGL
AERIASFIEVEQSLPAAGQGAVGIECRVDDEEVKALLAPLSDATTTTCVLAERAMNTRLQ
GGCQVPIGGYAIEQNGEIFLRALVGETDGSAIIRAEGKSAVENAEALGVSIAEQLLAQGA
DKILAKIYSA
>F4HFE1|hydroxymethylbilane synthase|EC 2.5.1.61|Gallibacterium anatis (strain UMN179)|TrEMBL
MQKDVLRIATRQSPLALWQANYIKHKLQVLYPQLTVELVTMVTKGDVLLDTPLAKIGGKG
LFVKELELALLEGRADIAVHSMKDVPMQFPQGLHLSVICEREDPRDAFVSNRYASLDELP
QNAVVGTSSLRRQCQLKALRPDIELKTLRGNVGTRLRKLDEGEYDAIILASAGLIRLGEQ
QRIRSFIAPEVSLPAVGQGAVGVECRQDDEWVNQLLKPLLHQDTWDRVIAERAMNNRLQG
GCQVPIAGYAILDGEQLFLRALVGAVDGSKVLRAEATAVRSQAEQLGIQVAEMLLAQGAQ
DLLSQVMKS
>E4ND90|hydroxymethylbilane synthase|EC 2.5.1.61|Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)|TrEMBL
MTPLRLGTRRSALAMAQSGMVAEAVAGITGRRVELVEITTYGDVSRESLARIGGTGVFVS
ALRDALLEGRIDLAVHSLKDLPTAAPAGLLLAAVPEREDARDALVARDGLTLAELVGKST
GRAVRVGTGSPRRMAQLNAWARARGAELETVAIRGNVDTRIGFVASGELDAVVLATAGLN
RLGRAAEITEHLDTELMLPAPGQGALAVECVDPTLAAVLARLDHRPTRAAVVAERALLAT
LEAGCSAPVAALATWAGTELRLDGVVGSTDGTELIKMSANGPLVPDGTAEEQAAALGRAL
AARLLDTGAADLMGERAR
>A1SE02|hydroxymethylbilane synthase|EC 2.5.1.61|Nocardioides sp. (strain BAA-499 / JS614)|TrEMBL
MSAPLRVGTRASVLATTQSGLVADQLREALGREVELVTVSTEGDRTQAAGIPLQGGSATG
VFVAALRDALLRGEVDVAVHSLKDLPTYPTEGITLAAVPVREDPRDVVVARDGLTLGELP
VGSRVGTGSPRRVAQLHALGLGLEVVGIRGNVDTRIGKVRSGECDAVILARAGLARIGRL
EAVTEVLDPLQMLPAPGQGALAVECRTDDPLAAQVAAALDDPRVRAAVTAERAVLATLEG
GCSAPIGALAEIVEGEDGDELWVRSVALSPDGALSVRRSASGSPSDAAGVGTRLGEQMLA
DGADRLGDPAEVQQ
>D0HAX8|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio mimicus VM223|TrEMBL
MVTRGDVILDTPLAKVGGKGLFVKELEVAMLEGRADLAVHSMKDVPVDFPQGLGLVTICE
REDPRDAFVSNTYAKIDDLPSGAVVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLD
AGEYDAIILAAAGLKRLELESRIRSFIEPEQSLPAVGQGAVGIECRLDDQRVRELLAPLN
HTDTADRVRCERAMNLTLQGGCQVPIGSYALLDGDEIWLRALVGEPDGSQIVRGEIRGPR
SEAEQLGITLAEQLLGQGAKEILERLYCEHE
>H1TLD2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21283|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E3J4N1|hydroxymethylbilane synthase|EC 2.5.1.61|Frankia sp. (strain EuI1c)|TrEMBL
MTSSSSTSLYPLGPAGRRPAAAARQAPASAGEAGGLPSRLRLGTRRSALALAQSGMVADE
LRTRLGIEVDLVHVVTEGDRNRAEISQLGSTGVWVSALREALLSGEVDLAVHSLKDLPTA
PPEGITLAAIPPREDVRDVLVSPTGRTLAQLGPGARIGTGAPRRAAQLRALGLGLDVVPI
RGNVDTRIKKAIDGEVDAVVLARAGLARLDRLDAITELLEPEVMLPAPGQGALAIECVAT
TLAPLTLLTVGTPEDQGAVTGMSCPVAPGSGVEIPLERLLRFVLDDAPSSVAVRAERAFL
AAIEAGCTAPVGALAQVLPARGQAPASEGEVRLRAVVASLDGTTVLRRELGGSTADPEAL
GRRLADDLLSAGAHTLMGIR
>Q5UY52|hydroxymethylbilane synthase|EC 2.5.1.61|Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)|TrEMBL
MTTRGETLQLATRGSDLALRQAATVRDSLSSRRLAVELVEVETTGDQIRDELIHRLGKTG
AFVRSLDEKVLDGELDAAVHSMKDMPTERPERLVVAAVPERAAAEDVLVTPDGRSLEELP
EGATVGTSSLRRKAQLLAERDDLTVEPLRGNVDTRLAKLLAPSLQQEHQERHEAEQEHEG
DAGDGDDADPDTDEEEEHPYDRTVEEWFDDLTEFERRAMERDPDVEYDAIVLAKAGLHRA
GLTRYVGMSDLDPDQFVPAPGQGALAVTAVDGDLALDIKDRLDDPQTRIETTVERTILEE
LGGGCVAPIGVHAQLEGGVVHTRVRVLSQDGTEEVSVGRDVPAEYHIESAQDLAAELAEQ
GADDLIAEAKRDSTEADDDASTAREEDEE
>F9QJQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium colombiense CECT 3035|TrEMBL
MIALGHPAELVTITTAGDRSSEPIESLGVGVFTTALREAMEEGRVDAAVHSHKDLPTADD
PRFAVAAIPLRNDPRDAVVARDGLVLAELPAGSLVGTSSPRRAAQLRALGLGLEIRPLRG
NLDTRLNRVSSGDLDAIVVARAGLARIGRLDDVTETLEPVQMLPAPAQGALAVECRAGDT
RLAAVLAELDDADTRASVTAERALLAELEAGCSAPVGAIAEVVESIDEEGRIFEELSLRG
CVAALDGSDVIRASGIGSPDRARELGLSVAAELFELGARELMSEARQDPARGN
>F9QJQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium colombiense CECT 3035|TrEMBL
MIALGHPAELVTITTAGDRSSEPIESLGVGVFTTALREAMEEGRVDAAVHSHKDLPTADD
PRFAVAAIPLRNDPRDAVVARDGLVLAELPAGSLVGTSSPRRAAQLRALGLGLEIRPLRG
NLDTRLNRVSSGDLDAIVVARAGLARIGRLDDVTETLEPVQMLPAPAQGALAVECRAGDT
RLAAVLAELDDADTRASVTAERALLAELEAGCSAPVGAIAEVVESIDEEGRIFEELSLRG
CVAALDGSDVIRASGIGSPDRARELGLSVAAELFELGARELMSEARQDPARGN
>Q4HT06|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter upsaliensis RM3195|TrEMBL
MKKLIIATRKSPLALWQSEFVADILRKTHGIEVHLEGFSTKGDILLDSPLAKIGGKGLFT
KELENAMLENKAHLAVHSLKDVPSFLPQGLVLAALSVREDDTDALLSELYKDLNALPQNA
KVGTTSLRRKMQLLSLRPDLHIINLRGNVNSRLKRLKGGEFDAIILASAGVKRLGLESEV
KFIYRFSKDELVPAATQGILGIQSPDKNEILTLLQCLNDEKSLIESTVERDFIRTLEGGC
QVPIGINAELMGEQITVRSILGLPDGSEILRDKRIILKKNYQGFGERLALEFIKRGAKEL
LKRAEAML
>G7HL04|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia cenocepacia H111|TrEMBL
MWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELEAALADGRAD
LAVHSLKDVPMALPDGFALAAIMEREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAML
RSRYPHLEVLPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLEARIRALLDVEASPPAA
GQGALGIEIAAHRDDVAAWLAPLHDPRTALAVEAERMVSRALGGSCEVPLAAHAVWRAGE
LYLTGRVSTTDGKRVLTAEECGAVVTVADALALGRAVSDELEAQGALDIVQALLAGSQAA
GKGDA
>I5GJB1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA9|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>E3PNZ2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O78:H11 (strain H10407 / ETEC)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A0K9J8|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia cenocepacia (strain HI2424)|TrEMBL
MGFLGKARVKRNCGNCGNCGQATSYVRHIRTTAPRPARKQAGRRLRARAGRGVRATIVRS
SIPSFDVPAMNSETPAAGPQQAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKI
LGMTTRGDQILDRTLSKVGGKGLFVKELEAALADGRADLAVHSLKDVPMALPDGFSLAAI
MEREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRSRYPHLEVLPLRGNLDTRLAK
LDRGDYAAIILAAAGLKRLGLEARIRALLDVEASPPAAGQGALGIEIAAHRDDVAAWLAP
LHDPQTALAVEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGKRVLTAEECG
AVVTVADALALGRAVSDELEAQGALDIVQALLASSQAAGKGDA
>D3PCG5|hydroxymethylbilane synthase|EC 2.5.1.61|Deferribacter desulfuricans (strain DSM 14783 / JCM 11476 / NBRC 101012 / SSM1)|TrEMBL
MNKLVIGTRGSKLALWQANHIKSLIESTHHIDVELKIIKTTGDKILDTPLAKIGGKGLFV
KEIEEELLNKNVDIAVHSMKDVPVELPDGLEVGVFPVREEPYDAFLSVKYNSLDELPDGA
VIGTSSLRRKIQLMRKYPHLVIKDLRGNVDTRIRKLTEGQYDAIILAKAGLKRLGLLEHV
KQTIDDTLMIPAVCQGTLGIEYREDDQDVQKVIGFLNHEETVFRTKAERAFLKRLEGGCQ
VPLGCIANLVGDRLILKGFLANLDGSKYIYEEIEGDKTDAVKLGLKLAKNILGQGGKEII
KEIYE
>B6R6Q2|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudovibrio sp. JE062|TrEMBL
MQTKPIRIGTRGSALALAQAHETRARLAKAHGLTDDDFEIVVIKTTGDQIQDRPLSEAGG
KGLFTKEIEEALLDKSIDLAVHSSKDMPTVLPDGLGMTAYLPREDVRDAFISPKVEKLTD
LPQGAVVGSSSLRRQAQIKRLRPDLDVVMYRGNLQTRLRKLDEGVVDATFLAYAGLRRLG
QGDLVTSLMDLEHFLPAVGQGAIGIEARLGDEETARILAPIHHAETESRLLLERAYLAEM
DGSCRTPIAGLSHVEGDRIKFRGEVIKPDGSQTHTVEGEGPVSDAEEIGRELGKELKAKS
GPNFLEL
>E7BEU3|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup A (strain WUE 2594)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>H4Y8T8|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC7D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C7DFQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Thalassiobium sp. R2A62|TrEMBL
MTYDLPVPTKPLKIGTRGSPLALAQAHETRERLAAAFDLPHEAFAIQVIQTTGDRIIDRP
LKEIGGKGLFTREIEQAMLDGSIDIAVHSMKDMPTLQPDGLLLDTYLPREDVRDAFIALD
GGTLADLPDGGVVGTSSLRRQAQLRLRRPDLQVVEFRGNLQTRLRKLGDKVADATFLAMA
GLNRLKMDDVTRTPIEVEEMLPAVAQGAIGIERRANDLRAADMLAAIHDRLTGQRLSAER
AFLQALDGSCETPIAALAELDGTSMRLRGEVLRPDGSEAIGDDVTILIEDGAAAGQAMAA
RLLANAGEGFFDWRVS
>Q21EF7|hydroxymethylbilane synthase|EC 2.5.1.61|Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)|TrEMBL
MKKIRIATRKSELALWQANDVKAKLEALYPSLEVELFPLVSRGDKILDVPLAKVGGKGLF
VKELEHALLADEADIAVHSMKDVPMEFPEGLELAVILEREDPRDAWVSAGYENLDALPAG
GVVGTSSLRRQSQILARRPDITVKFLRGNVNTRLAKLDAGEYDAIILAAAGLKRLKFGDR
IRSYLSPEESLPAGGQGAVGIECRSADSETLKLLQALHHTITAEQVLAERAMNRRLEGGC
QVPIGCFAVHQNNQLWLRGLVADPDGSKVIYDEMTGAAADGEKMGVELAEKLLAAGADKI
LKAVYDNQ
>I0IM65|hydroxymethylbilane synthase|EC 2.5.1.61|Leptospirillum ferrooxidans (strain C2-3)|TrEMBL
MTQILKIGTRGSELALWQARHVAALIEKTSGVKSELTIIKTSGDMILDRPLSDVGGKGLF
VKEIEEALLSRQVDLAVHSMKDVPAEMPEGLILGVTMEREDPRDVFVSIHYPSLRKLPTG
AKLGTSSLRRVSQVRRIRPDLVIVPVRGNVGTRLRKLEEGQVDALLLAGAGMKRLGLEHK
ITEWLLVSDLLPAIGQGALGLEYRESDTITSSIASRLFHSDTHIAVSAERGVLKSLAGGC
QLPVAAYATVKRSGWVQLEARVMSLSGDRMLTEKVTGPSEEAMELGLAIGQTLLEKGGKE
ILDEIRLGS
>D8JY37|hydroxymethylbilane synthase|EC 2.5.1.61|Hyphomicrobium denitrificans (strain ATCC 51888 / DSM 1869 / NCIB 11706 / TK 0415)|TrEMBL
MQAARIRIGTRGSPLALAQAHEVRDRLAKAHGLSEDAISITIIKTTGDRVTDRPLSDIGG
KGLFTKEIEDALFAREIDIAVHSMKDMQTELPDGLALGAVLPREDPRDAFISLKHANISA
LPTGAIVGTSSLRRKSQVLSIRPDLSVIDFRGNVETRLRKLKDGIAEATFLAVAGLNRLG
LSDRITAIVPSADMLPAAAQGAIGLEIRTGDKEAEAFVAPLNDVNSQRAVTAERAFLARL
EGSCRTPIAAHATIDGEQLSFRGQVLSLDGQQKYDVSRSGAANASRDIGLAAADEVLSKA
DPALLVRSSA
>F9T682|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio tubiashii ATCC 19109|TrEMBL
MTQQTPIRIATRKSPLALWQAHYVKDALMAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQIKESRPDLVIKELRGNLGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIKSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHKETADRVLCERAMNLTLE
GGCQVPIGSYSLIDGDNIWLRALVGEPDGSKIVRGEIRGSRTDAEALGIELANQLLDQGA
KEILTKLYAEHE
>H8NA96|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia prowazekii str. Dachau|TrEMBL
MINSIRIGTRNSTLALIQTNLVIEQIKQIFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGKIPVELVIAAVLEREDPRDVLVCLNYQSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDAIILSYAGLKRLNVFN
QKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPERAFLEYLDA
NCSTPIAAYAQYLDAYNIQIDFMLGNLDCTKIIFQTEITNIKTSKICGIKAAKMMLAQQ
>D6SKM8|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfonatronospira thiodismutans ASO3-1|TrEMBL
MKKVVIATRGSKLALWQAEHISSRLRERYSGLEVELLKVKTTGDKILDVPLAKVGGKGLF
VKEIEEALMDGRADIAVHSMKDMPAELPRGLKLGIIPERESRFDVLLSTSYPDISSLPTG
ATVGTSSLRRQAQILHMRPDLEIQMLRGNLDTRLRKLKEGIYDAIIVAAAGMSRLNMHAD
YVTELSPPYFLPAVGQGALGIEYLQDRQELDELLGFMDDFSTRYCIECERAFLAELEGGC
QVPIACYCRHEGNNIQATGLVCDLKGERMIRKSVSGKPKDARSLGVDMARQVLEAGGREI
LAELYACQDDNQD
>G8V6U2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 11819-97|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E0T565|hydroxymethylbilane synthase|EC 2.5.1.61|Edwardsiella tarda (strain FL6-60)|TrEMBL
MQSMTTATQPTLRIATRQSPLALWQAHYVRDQLLTHWPQLTIELVPMVTRGDVLLDTPLA
KVGGKGLFVKELELALLEGRADIAVHSMKDVPVAFPDGLGLVTICQREDPRDAFVSPRFA
SLEQLPPGSVVGTSSLRRQCQLRAARPDLQIRDLRGNVGTRLAKLDAGDYDAIILAAAGL
KRLQLDDRIRTPLTPEQSLPAVGQGAVGIECRLADDATRRLLAPLNHADTALRVCAERAM
NTRLEGGCQVPIGSYAEIDGDQLWLRALVGAPDGSRIIRGERRGPLTQAEAMGTALADEL
LARGARTILDAVYCQKA
>B3ALL9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC4486|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>A8ACV3|hydroxymethylbilane synthase|EC 2.5.1.61|Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALIAQHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLEKRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNQYNN
LDELPAGSIVGTSSLRRQCQLAERRPDLVIRSLRGNVGTRLSKLDNGDYDAIILAVAGLK
RLGLTSRIRTALPPEISLPAVGQGAVGIECRLDDARTQALLAPLNHEETALRVKAERAMN
TRLEGGCQVPIGSYAEIIDGEVWLRALVGAPDGSQMIRGERRGLPQDAAQMGISLAEELL
ANGARAILTEVYNGEAPA
>B1Q731|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum NCTC 2916|TrEMBL
MNFIIATRRSNLAQVQTEIIIDLLNKKHDIKCEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEIMEEHPKKDLFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
>I0MGF8|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Heidelberg str. 41563|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>E0URL4|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurimonas autotrophica (strain ATCC BAA-671 / DSM 16294 / JCM 11897 / OK10)|TrEMBL
MKKLTIATRVSDLALWQAYHIKERVEVNYPEIEVVLNKIVSNGDKVLDKPLALIGGKGHF
TKELEDEMLAGNAELAVHSLKDVPTYIPDGLELVAVTQRQDQSDVFLSHTYATLDDLPKG
AVVGTTSLRRRMQLLQKRPDLKVKDLRGNVNTRLRKLKEGQYDAIILAWIGLNRLDLLKD
IPYTQKLSLDMMIPPMGQAALGIEIISDNEKVREIAKSLNDEDTFTCTQIERDFISKIGA
GCSAPVACNAVIDGDNVVFRTMIGFPDGTNIMQKKVVKSKNESENLGKELAQKMINNGAL
KLLKNAEKIAFKDEMPQRL
>A4XNY8|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas mendocina (strain ymp)|TrEMBL
MPREIRIATRKSALALWQAEYVKARLEQAHPGLLVSLVPMVSRGDKLLDAPLAKIGGKGL
FVKELETALLENEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTYDSLDALPA
GSVVGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFQD
RIRSSISAEDSLPAGGQGAVGIECRSADAEIHALLAPLHHRETALRVTAERALNKRLNGG
CQVPIACYALLENDQLWLRGLVGQPDGGLLLRAEHRAASSDAEALGVRVAEALLAQGAEA
ILKAVYGEAGHP
>E4PK73|hydroxymethylbilane synthase|EC 2.5.1.61|Marinobacter adhaerens (strain HP15)|TrEMBL
MSKRTLRIATRSSALALWQAEFIKAELERLHDNITVELVKIKTQGDKILDVPLAKIGGKG
LFVKELEEAMLDGRADLAVHSMKDVPMEFPEGLGLVAICEREDPTDAFVSNHYDNVDALP
HGAVVGTASLRREAQLRAYRPDLEIRVLRGNVNTRLAKLDAGEYEAIVLASSGLKRLGFH
ERIRYCLPDTLSLPAVGQGALGIECRVDDQDLLAMLEPLKHKDTWDRVTAERALNRRLEG
GCQVPIAAYALLEDDDTIWLRGLVGAVDGTQIFRVEGRAPRAEGERLGRELAEDLLALGA
DKVLAEIYGHTPT
>A0Y0E4|hydroxymethylbilane synthase|EC 2.5.1.61|Alteromonadales bacterium TW-7|TrEMBL
MTEKTKLVRIATRKSALALWQAEFVKAQLEHFHDDVRVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLDGRADIAVHSMKDVPVEFPEGLALHTICEREDPRDAFVSNHFANLNE
LPEGAVVGTSSLRRQCQIRALRPDLEIRDLRGNVNTRLAKLDAGQYDAIILAAAGLIRLE
MGERIADYIEPEVSLPANGQGAVGIECRIEDEVTKALLAPLEHTHTRIRVNAERAMNRRL
EGGCQVPIGAYALVDSEQVHLRGLVGAIDGSEILRDEVAGHINDAEKLGIELAEKLLAQG
ADKILADVYRDA
>D5H9G8|hydroxymethylbilane synthase|EC 2.5.1.61|Salinibacter ruber (strain M8)|TrEMBL
MSISDPLVLGTRGSELALRQANVVRSRLEAAGHRVELETITTRGDEATDTPISEIGDEAV
FTKELDRALLQGGVDLAVHSLKDIPSTVPSGLALAAIGEREDPRDAFVAHPSFDGHLHDL
PEGATVATASLRRTAQLLTWRSDLEVVPVRGNVDTRLEKLSESDWTGMVLAVAGLVRLGL
SLHIRDRIDPSLIVPAVGQGALGIACREDQDALRDLLRETLHHAPSGHAANAERAFLKKV
GGGCQVPLGAWAHIDDGTLVLDACIAALDGSEHYRDERRCAPEDGAAVGRELAADLLAMG
GDHILDDVLGESREGTSNSPFRP
>G6WUC7|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glutamicum ATCC 14067|TrEMBL
MTLKIGTRGSKLATTQAGTIRDQLKHYGRDAELHIVTTPGDVNMSPVERIGVGVFTQALR
DVLHSGECDVAVHSMKDLPTAADPRFHLVVPTRADSREALIARDGLTLAELPEGAKVGTS
APRRISQLKAIRPDLEILPLRGNIDTRMGKVTSGELDAVMLAYAGLTRVGMQDRATEVFD
ADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAERTVLNRLEAGCTAPVAA
HATLDGYSGDTMTLTAGVYALDGSDQLVFSAEGDGARPEELGELVAQQLIDAGAANLLGD
RS
>G6WUC7|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glutamicum ATCC 14067|TrEMBL
MTLKIGTRGSKLATTQAGTIRDQLKHYGRDAELHIVTTPGDVNMSPVERIGVGVFTQALR
DVLHSGECDVAVHSMKDLPTAADPRFHLVVPTRADSREALIARDGLTLAELPEGAKVGTS
APRRISQLKAIRPDLEILPLRGNIDTRMGKVTSGELDAVMLAYAGLTRVGMQDRATEVFD
ADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAERTVLNRLEAGCTAPVAA
HATLDGYSGDTMTLTAGVYALDGSDQLVFSAEGDGARPEELGELVAQQLIDAGAANLLGD
RS
>F8AYY4|hydroxymethylbilane synthase|EC 2.5.1.61|Frankia symbiont subsp. Datisca glomerata|TrEMBL
MAMSASRLIRIGTRSSPMALAQAERVRAELTALNPDLTAEIVPITTSGDRWTGPLSTLGG
KGAFTKEVDEALLAGRADLAVHCMKDVPGDRPVPAGTVFAAYLPRDDIRDALIHPGGRTL
DQLPAGTRVGTSAVRRIAQLAQSHPHLETVPIRGNANTRLARLDDGAADALLLAVSGLER
IGQAGRITEILSAETMCPPIGAGVLGLQCREDDTDTAQLVAGMDDIDARRQVTAERMLLH
VLQGHCNSPIAGHAHTEPDGRLSLRAKVFSPDGKTVLDAHEWGPGTDPTTLGASVAVALL
RQGAQDLLNAIPH
>E8KRB9|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis VMC66|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKAIHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLANLPE
GALIGTSSIRRQVQLQAQRPDLTFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQTLETSLCLPAISQGALAVECREEDEELRSLLAAVQDEKTAAEVAVERAVLAQM
NADCTFPIAAFAQKNGQGYQLEAMLAKEDGQCIFVSLQGQDGQELAEQAVRQLADKGAVG
MPWLKK
>F5W6D1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21305|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E7PGP8|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. glycinea str. race 4|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDELP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
NRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPAGSVLLHAEARAPQTSAQALGVQVAEALLAQGAA
DILKAVYGEANNE
>A3WRC8|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrobacter sp. Nb-311A|TrEMBL
MQSSDETEILATIGTRGSPLALAQAHEVRDRLARAHQVAPERIAIKTIRTSGDAIQDRPL
FDVGGKGLFTKEIEEALLAGAIDFAVHSSKDVPTFLPDATWLPAFLPREDVRDVFISPRA
ASLHDLPAGSIVGTASLRRQAMVLRLRPDLKVNALRGNVETRLRKIDAGEADATLLALAG
LNRLGLQDKATRILETEEFLPAVGQGAIAIESRRDDDRINAFVKAIGDSETEVALSAERS
FLALLDGSCRTPIGGHCRVNGDRIHFRGLIISPDGTESYETTREGARADAAALGADAAHE
LRERAGEKFFTLFAGA
>F0IPQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK150|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKALHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLTFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRQLLATVQDEKTAAEVAVERAVLAQM
NADCTFPIAAFAQKNGQDYQLEAMLAKEDGQCVFVSFQGQDGQELAEQAVRQLADKGAVG
MPWLKK
>G2MN47|hydroxymethylbilane synthase|EC 2.5.1.61|halophilic archaeon DL31|TrEMBL
MSTDRTLRLATRGSDLAMRQAASVQERVGTRRRPVELVKVETDGDRIQDELISNLGRIGA
FVHALDQEVVNGDCDAAVHSMKDMPTEFADGIVVAAVPERAPAGDLLITEDGRELDELRE
GAVVGTASLRRTAQLLNARPDLDVRPLRGNIDSRIEKLLAPKLQREHERRLGDEEDDEST
EMREYNIDPEGVLDEENEGLEALENEEDEFDISVEDWFDSLTELERNALGQEFDHEFDAI
VLAEAGLQRSGLDHQIGTTRLPEDRFVPAPAQGAIAVTAVDEEVVTRLRTKLDHPPTRVA
TTVERTVLAELGGGCVAPLGVHAKVQGQHVNVRAQVLSTDGTEVITDSRDLPVENHAYAA
EQFADDLADRGAATLVEAAKEV
>H2IWQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 / CIP 78.65)|TrEMBL
MVDKIIRIATRQSPLALWQAQYVQSRLMACHPGLQVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELAMLDGRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNQYTRLTDLP
HGSIVGTSSLRRQCQLRQKRPDLVIRDLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
NRITCALTPEECLPAVGQGAVGIECRLDDQTTRDLLAPLAHRETTVRVQAERAMNMRLEG
GCQVPIGSYAELEGDELWLRALVGAPDGSQMVCGERRGPSANAHHMGIDLAEELLANGAR
EILHEVYQGNAPK
>H7SY28|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 1098|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>D5QQ40|hydroxymethylbilane synthase|EC 2.5.1.61|Methylosinus trichosporium OB3b|TrEMBL
MTTAILTIGTRGSPLALAQTHEVRRLLAAALGAPEEALPIEIIRTTGDMIQDRPLAESGG
KGLFTRELDIALAEGRIDLAVHSSKDLPTHLPPEIAIAGFLPREDVRDAWIGRGGASLAD
LPQGAVVGTASLRRGAQVKRLRPDVSVTLLRGNVETRLHKVESGEVDGTLLALAGLKRLG
LADKATAILPLEDFLPAAGQGAIAITKRAGDARTRDALAPILDAATGAALAAERAFLTVL
DGSCRTPIAAHARVDGDAMEFHGLALRADGSEIYEARRRGAAIDAARLGDDAANEILLRL
PHGVAGLS
>C9R7U0|hydroxymethylbilane synthase|EC 2.5.1.61|Ammonifex degensii (strain DSM 10501 / KC4)|TrEMBL
MRKSKRCLRIGTRGSDLALAQTEQVLQILRERWPHYTYEIVKIKTTGDKVRNLALPRIGG
KGLFTKELEVALLEEKIDLAVHSLKDLPTELPEELCVGAVLPREHPGDVLISLTGAGLED
LPEGARIGTSSLRRQAQLKAARPDLNFVPLRGNVPTRLRKLEKGECEAVVLAWAGLRRLR
LDLTGRMTLLPYQVCLPAVAQGAIGVEMRKEDRELRKMVEVLDDPTTRLEVTAERAFLRW
LGGGCHVPIAALARVAGAEILLEGLVADPEGKRIVRGQESGSTAYPEEVGIRLAERLLRE
GAEELLRG
>G7G274|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas sp. BSi20495|TrEMBL
MTEKTKLVRIATRKSALALWQAEFVKAELERFHADVCVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLDGRADIAVHSMKDVPVEFPEGLELHTICEREDPRDAFVSNNFANLGE
LPQGAIVGTSSLRRQCQIKALRPDLDIRDLRGNVNTRLGKLDDGQYDAIILAAAGLIRLE
MESRIADYIEPEVSLPANGQGAVGIECRIDDEVTKALLAPLEHTQTRIRVNAERSMNRYL
EGGCQVPIGAYALVDGEQVHLRGLVGAVDGSEILRDEVTGHVNDAEKLGIELAKKLLAQG
ADKILAEVYRDA
>F9AKI1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HE39|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSKIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>I2T217|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 96.0497|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>I4SK72|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli KD2|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A9CX67|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella benthica KT99|TrEMBL
MSQNVIRIATRKSPLALWQAEFVKAELEKFHPGLTVELLPMSTKGDIILDTPLAKVGGKG
LFVKELEVAILEDRADIAVHSIKDVPVDFPDGLGLEVICEREDPRDAFVSNDYKSIGDLP
QGAVVGTSSLRRQCQIRGMRPDLKIIDLRGNVGTRLGKLDAGNYDAIILAAAGLKRLKLE
ERITSFISTEDSLPANGQGAVGIECRTDNERVKALLAPLEHAETRFRVTAERAMNTHLEG
GCQVPIGAFAEIQGDTLTLRGLVGNPDGSKIITGTCVGPKTDAKAIGIALAEELLGKGAK
EILDAVYIK
>D6Z0L2|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2)|TrEMBL
MWKTIRIGTRASMLALAQSNWIKGRIEAQYPGCSVELVKIVTKGDKIVDVPLAKVGGKGL
FVKEIEEALLRREVDIAVHSMKDVPAELPEGLHIGIITEREKPFDAFITNNYKTLAEVPQ
GATIGTSSLRRKAQLARLRPDLKIEDLRGNLDTRLRKLDEGVYDAIILAAAGLNRLDLFH
RATFCFQPDEMLPAVAQGAVGIELRRADEDLLQMLSFMDHRETTLAVHAERSYLKRLEGG
CQVPLAGFATLAGQTLTINGLIASVDGGKMVKAKHSGPAAQAKTLGLELAEELLAMGGRE
ILEEVYGASLK
>F7X0G1|hydroxymethylbilane synthase|EC 2.5.1.61|Sinorhizobium meliloti (strain SM11)|TrEMBL
MQTKPFRIGTRGSPLAMAQTHETRDRLAAAHGLPPEMFEIVILSTKGDRITDRSLAEIGG
KGLFTEELEQQLLSGDLDFAVHSSKDMPTKLPEGLFLSAFLPREDIRDAFVGRSAKRLVD
LPQGATVGSSSLRRQALIRRLRPDIDVITYRGQVETRLRKLAEGQVDGTLLAYAGLRRLG
MEHVPTELLDPEEFPPAPAQGAICVEARIGDDRINTLLAAIDDPRTHEAVSCERGFLATL
DGSCRTPIAGYAQSDGTHIRFAGMILTPDGTTSHQIEIDGRAADAERLGQEAGERIRAKA
GPGFFSSWS
>I0EGF9|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori PeCan18|TrEMBL
MGKLVIGSRGSELALWQANHIKERLKKECSMESEIQIVKTTGDKILDAPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLQRLNVQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDEVKIQAVLGLPNGKEVITKEKQGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>D8IZS3|hydroxymethylbilane synthase|EC 2.5.1.61|Herbaspirillum seropedicae (strain SmR1)|TrEMBL
MKEFPPSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVG
GKGLFVKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALD
ELPDGAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRL
GLKARIRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRI
FGASCQIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKAR
GADDILAACKAQADAASA
>E6WHF7|hydroxymethylbilane synthase|EC 2.5.1.61|Pantoea sp. (strain At-9b)|TrEMBL
MLDKIFRIATRQSPLALWQAQYVQQRLMAAHPGLQVELVPMVTKGDVILDTPLAKVGGKG
LFVKELELAMLENRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNHYDSIDALP
QGAVVGTSSLRRQCQLSARRPDLVIRSLRGNVGTRLGKLDAGEYDAIILAAAGLKRLGLE
DRIRFALPAEISLPAVGQGAVGIECRLDDAELITLLQALNDGDTAVCVRAERAMNTRLEG
GCQVPIGSFAVLEGDQLWLRGLVGSPDGSQMITGERRGPRDQAEQMGISLAEELLDNGAS
EILRDVYQGQPPA
>H4B9I3|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1524|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSELPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>E8J8F4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. LSU-61|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>I5QXT9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW09109|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F3TH07|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21193|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E2N6H5|hydroxymethylbilane synthase|EC 2.5.1.61|Capnocytophaga sputigena ATCC 33612|TrEMBL
MKTIRIGTRDSELALWQAKTVQHQLEALGYSTEIVSTKSHGDIELSKPLYEMGVIGIFTK
ALDIALLNGEIDIAVHSMKDVPTALPDGIVVGAVLKRGNPHDVLVYKGDLSFLDVEIATI
ATSSLRRKAQWLHRYPHHNIENLRGNVNTRLQKLADNPWNGAIFAAAGLERINKLPENHL
RLDWMFPAPAQGAIMVTLHEDNVPLQGVLLRIHDGNTYVATQVERAFLRALEGGCTAPIG
AFAQYDGQQKVYFKGGLWSEDGKKAAVIEEILTQINEHTGEQLAEKVKSKFEN
>F0KKN2|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter calcoaceticus (strain PHEA-2)|TrEMBL
MLEFMKTLKIATRQSPLALWQAEHIRARLEELHPDLTVELVKFVTQGDKILDTPLAKIGG
KGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNRFETFAD
LPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDEGQYDAIILASAGLKRLG
LSERIRHCLTPDISLPAVGQGALGLECRAVDQDVLALIQPLLHEETDVCVRAERAFNAYL
EGGCQVPIAGYATLQNGQIHIEGRVGSPDGQTLLRAELTDEANNAQQLGENLARNLLDQG
AGELLKALY
>F4BII4|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella cf. novicida (strain 3523)|TrEMBL
MKQITIASRESKLALWQTNFVKKYIQKELNIPCEITTMKTQGDIILDKPLNKVGGKALFM
KELEIAMQNGKANIAVHSLKDVPYQLPQGFCLASFMPREDPRDAFVSNKYSSIDDLPKGA
IVGTSSLRRKAQLLHYRDDLVIKDLRGNVQTRLSKLDSGEYDAIILASAGLIRLELNERI
TQFIPVEISLPAVGQGIVVIEALDRDVELLEKLQKLNCSTSFRMATAERAFNQELKGGCH
VAIGAYAELNNNQITLTAMVASSDGKKILKRKMIGDDPTKVGKLLAREMIELGAYKILES
>C7LWF7|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfomicrobium baculatum (strain DSM 4028 / VKM B-1378)|TrEMBL
MNTIRIATRGSKLALWQAHHISGLLRAQYPGMTVELNIIKTKGDKILDVPLAKIGGKGLF
VKEIEEALLADEADIAVHSMKDVPAQLPEGLKLGIIPEREQPTDSFLSVNYPDIASLPAG
ARVGTSSLRRQTQLMGLRRDLCILSLRGNLDTRVGKLMAGEFDAIIVATAGMNRLELSAP
HMQELAPPMFYPAVAQGALGIEYRADRPQLDELLAFLDHAPSKICVEAERSFLFGLDGGC
QVPIAGYATLSGTEITLTGLVADLCGERVIRRQATALSHAAVELGAQVAKAVLADGGKEI
LDEVYRSGAAV
>B9JU77|hydroxymethylbilane synthase|EC 2.5.1.61|Agrobacterium vitis (strain S4 / ATCC BAA-846)|TrEMBL
MQTKPFRIGTRGSPLALAQAHETRERLATAHGLSPDMFEIVVLSTTGDRITDRSLAEIGG
KGLFTLELEQQLLSGGLDFAVHSSKDMPTALPDGLEISAYLPREDMRDAFIGRTAPKLLE
LAEGAVIGSASLRRQALIRRLRPDLQVITYRGAVETRLRKLAAGEVDATLLAVAGLKRLD
KETVITQYLDLESFPPAPAQGAICIEARVDDRRIQDLLAPINHRPTFDAVSCERAFLAAL
DGSCRTPIAGYAISDGEMIRLTGTILTPDGQVSHSVEAEGRCADGLALGWSAGEKVRDKA
GPGFFEGWT
>G1YX43|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli STEC_C165-02|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H3S811|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1605|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>A1ZNC8|hydroxymethylbilane synthase|EC 2.5.1.61|Microscilla marina ATCC 23134|TrEMBL
MHIRIGTRGSKLALWQANYVADLLQKGGATTELVMVETKGDKILNKALSKIGSKGVFTEE
LEEHLRQKEVDIAVHSAKDVQSTLPDDLELIAFSEREEVHDVLISFNTDARLDTFNSSYI
IGTSSTRRVAQLKHYYPKIRTADVRGNLQTRMKKLEKGNYDALILAYAGVHRMGFSKYIV
EDLSPNKFIPAVGQGCVAIEAAKDLNNDKVAMIRQCVNDKKTEQCLRAERSFLKTLEGGC
SIPVFGLARIKKNQIELKGGIISLNGQDLVKQQAKGVLDDGVSIGKQLAERILQDGGEEI
LSEIKANL
>G2EKQ7|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glutamicum S9114|TrEMBL
MTLKIGTRGSKLATTQAGTIRDQLKYFGRDAELHIVTTPGDVNMSPVERIGVGVFTQALR
DVLHAGECDVAVHSMKDLPTAADPRFHLVVPTRADSREALIARDGLTLAELPEGAKVGTS
APRRISQLKAIRPDLEILPLRGNIDTRMGKVTSGELDAVMLAYAGLTRVGMQDRATEVFD
ADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAERTVLNRLEAGCTAPVAA
HATLDGYSGDTMTLTAGVYALDGSDQLVFSAEGDGARPEELGELVAQQLIDAGAANLLGD
RS
>G2EKQ7|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glutamicum S9114|TrEMBL
MTLKIGTRGSKLATTQAGTIRDQLKYFGRDAELHIVTTPGDVNMSPVERIGVGVFTQALR
DVLHAGECDVAVHSMKDLPTAADPRFHLVVPTRADSREALIARDGLTLAELPEGAKVGTS
APRRISQLKAIRPDLEILPLRGNIDTRMGKVTSGELDAVMLAYAGLTRVGMQDRATEVFD
ADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAERTVLNRLEAGCTAPVAA
HATLDGYSGDTMTLTAGVYALDGSDQLVFSAEGDGARPEELGELVAQQLIDAGAANLLGD
RS
>F8BNN5|hydroxymethylbilane synthase|EC 2.5.1.61|Oligotropha carboxidovorans (strain OM4)|TrEMBL
MRIGTRKSVMALAQTSEIARQLTAADPALDVEIVKFETTGDQDQTGKLLDLGGKGGAFVA
QIRDAVREGRLEAAMHSLKDMPGNEDTPGLVIGATLTRDPPTDALVVRHGVTLADLRRTG
GKGFKIGTNAVRRAAYVRRLFPECEIIHFRGAADTRIRKLDNGEKQRLPEGGEVGPADAL
VMAQAGLERVGCADRIAHCFSPDEILPAVGQGIVAVECAASDWCTLARLAQIDDPVSRCC
AAAEREVLWVLNGHCNSPIAGYAIVEGDDVLLKAAVLDEANDHFIEVTRRGPASRPRELG
RAVAFELLAKGAADVIARTRPVSAH
>D4ZCR7|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella violacea (strain JCM 10179 / CIP 106290 / LMG 19151 / DSS12)|TrEMBL
MSQNVIRIATRKSPLALWQAEFVKAELEKFHPGLTVELLPMSTKGDIILDTPLAKVGGKG
LFVKELEIAMLDGRADIAVHSIKDVPVDFPDGLGLEVICEREDPRDAFVSNDYKSIDDLP
KGAVVGTSSLRRQCQIRAMRPDLKITDLRGNVGTRLGKLDAGNYDAIILAAAGLKRLKLE
ERISSFISAEESLPANGQGAVGIECRTDDERVKALLAPLEHTETRYRVTAERAMNTHLQG
GCQVPIGAFAEIQGDTLTLRGLVGNPDGSKIITGTSVGPKTDAKAIGITLAKELLSKGAK
EILDAVYIK
>H7QUI0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 111-3|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>I2VFH9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 96.154|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>E6Q6F7|hydroxymethylbilane synthase|EC 2.5.1.61|mine drainage metagenome|TrEMBL
MSLPLSLRLAGRLVVLLGAGSVAARKARTFVEAGAKLSVVAPSVGEAMEALLAAHPDVRC
ERRAYREEDLADAFLCVAATDSPVVNEGAMRAARARGILTIDSTEPARGDATMPAVVRVG
ELTFSIDSGASTPAFSKRIAREIALHFDARYDAAARTLAIARSYVRETLSPSQRAVVMRA
LSELPLDELAAMDRNRIEDAVEATAATVLADGAAPSTSSAICATRGSALALWQSRHVAAR
LAQNGIATTMLALSTVGDRDRSSALAAMGEQAIFVKELERALADGRADYAVHSAKDLPSA
LPAGMQLSAISLREDPRDVYCSERYATFAELPAGARVGTSSPRRRAQLYSLRSDLAYVEI
RGNVDTRLRKLREGEYDAIVLAAAGLRRLALRATHTVPFPIEQLLPAAGQGALAVETLLD
APLAGALRAALNDEPTERAVIAERAALRELGAGCTAPVGIHGAYEGGGLLLRGRVSSTDG
APAIAAELRAPAADSAAAEELGCSLARALLARGAASLLPRSGPLAGRRILLPRSVERTSR
IAARLRALGAEVTELRAGEEPDGAPDLLAIPSSGAAAVAAPWLSLWGEHGVRPLVVAMGP
ESASAIERAGLPPDGIAPIPEIDAFTACIVGLLASP
>D1AFK5|hydroxymethylbilane synthase|EC 2.5.1.61|Sebaldella termitidis (strain ATCC 33386 / NCTC 11300)|TrEMBL
MRKIVMGTRGSVLAVAQAETVKKMLIEKIPGLTVEIKKIVTSGDRDQTTNWGGDSSLKSM
FVKEIERELLEGTIDFAVHSMKDMPQISPEGLINACFPIREDNRDVLVSKNNTVFSEMPS
GSVIGTSSLRRKSAVTELYPEMEIKPIRGNIHTRLGKLDSGEYDGIILAAAGLIRTGLES
RISEYIDPEKMPPAPAQGILCVQCRENNMEILEILKEIDDRETRIICEAEREFSRIFDGG
CHTPMGCFAVIKEEEIFLKGMFCSGEKMYFGEAGGSIEKPKEAAQKLAEIIRRQINE
>F7QKS2|hydroxymethylbilane synthase|EC 2.5.1.61|Bradyrhizobiaceae bacterium SG-6C|TrEMBL
MAAISLRIGTRKSKMALAQTEEIARRLEAAAPDLKVEIVKFETRGDTDQTGLLLPHGGKG
GAFVAEIREAVIAGKLHAAMHSLKDMPGNEDTPGLVIGATLSRDPPTDALVLRAGVTFED
LKHAKGKGFKIGTNAVRRAAYVRRLFPEIEVIHFRGAADTRVRKLDNGEMQKLADGGEVG
PADALIMARSGLERVGLADRIGHEFAALEMLPAAGQGIVAVECAAHDWQTRQYLALIDDP
VAHLCADAEREVLWVLNGHCNSPIAGYSTIDGREMTLTASVLDLEGDRLLEATRRGPADK
PRELGRAVAFDLLAQGAAAIIETSRPE
>D3RH92|hydroxymethylbilane synthase|EC 2.5.1.61|Klebsiella variicola (strain At-22)|TrEMBL
MTVTSMLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLNVELVPMVTRGDVILDTPLAK
VGGKGLFVKELELAMLEGRADIAVHSMKDVPVEFPEGLGLVTICERDDPRDAFVSNHYAS
IDELPAGSVVGTSSLRRQCQLAATRPDLVIRSLRGNVGTRLSKLDNGEYDAIILAAAGLK
RLKLEARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTQALLAPLNHAETAVRVRAERAMN
TRLEGGCQVPIGSYAELVNGELWLRALVGAPDGSQMVRGERRGPAEQAEALGISLAEELL
DNGARDILAAVYDGEAPR
>A4X1U2|hydroxymethylbilane synthase|EC 2.5.1.61|Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)|TrEMBL
MKVPLRLGTRGSALAMAQSGQVAEALTAATGTPVELVEVVTTGDRSTAPVHQLGVGVFVS
ALRDALAAGAIDFAVHSYKDLPTAAAPGLYVAAVPPRQDPRDALVATGGRTLAELPPGAR
VGTGALRRIAQLHALGLQLEVQPIRGNVGTRLARVLGPEADLDAVVLARAGLARLDRTDT
ITETLDPMLMLPAPAQGALAVECRSDDSALVELLAVLDHAPSRATVVAERALLATLEAGC
SAPVAAYAELAEGDVGEEIYLRGAVISPDGTRDLRLSRTGTPADAVEIGKALATDLLDLG
ADSILGQQRNLGPGTQQFGSTV
>G8PLW5|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudovibrio sp. (strain FO-BEG1)|TrEMBL
MQTKPIRIGTRGSALALAQAHETRARLAKAHGFTDDDFEIVVIKTTGDQIQDRPLSEAGG
KGLFTKEIEEALLDKSIDLAVHSSKDMPTVLPDGLGMTAYLPREDVRDAFISPKVEKLTD
LPQGAVVGSSSLRRQAQIKRLRPDLDVVMYRGNLQTRLRKLDEGVVDATFLAYAGLRRLG
QGDLVTSLMDLEHFLPAVGQGAIGIEARLGDEETARVLAPIHHAETESRLLLERAYLAEM
DGSCRTPIAGLSHVEGDRIKFRGEVIKPDGSQTHTVEGEGPVSDAEEIGRELGKELKAKS
GPNFLEL
>H0MT50|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035327|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I0E376|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori Shi417|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIRAVLGLPNGKEVIAKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKAQLF
>F5YLI6|hydroxymethylbilane synthase|EC 2.5.1.61|Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2)|TrEMBL
MIREIRIGSRESVLAIAQTRLIMDPIMRAHPELSLRLVTMKSEGDLNPDLPLGFTGKALF
TGTLERALVAGELDLCVHSLKDMAETQPEDLPILAIPKRGNPWDMLIPPQDFFQGKDEKD
IFTALEKALPIGCSSLRRRIQLQALAPELHSAPIRGNVPTRLSKLDSGQYGALILAAAGL
ERLGITRQGGRLFSLQEMIPAAGQGTLAIQGRRGEDYPFLELLRDPISEEEALAERALIR
TLGCGCSSPAAAYAKISGNEIFITGMYTPLETEGIGLANVTNIDEIPFAREEISGDRRHA
LQLAEELARRLIQAASRDPGRTPQRDAPEGGRR
>E8DBK4|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. MB110209-0055|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>B3R611|hydroxymethylbilane synthase|EC 2.5.1.61|Cupriavidus taiwanensis (strain R1 / LMG 19424)|TrEMBL
MSSATPSSATAVVSRNLPQKLVIASRESRLALWQAEHVRAALQQYYPACDVSILGMTTRG
DQILDRTLSKVGGKGLFVKELEFAMDEGRADLAVHSLKDVPMELPPGFTLAAVMEREDPR
DALVSSAYASLDEMPPGTVVGTSSLRREAALRSRYPHLVVKPLRGNLDTRLGKLDRGEYG
AIILAAAGLKRLGLGDRIRALIPLEASLPAAGQGALGIETLSTRPELAEWLAPLNHQPTA
LAVTAERAVSRRLGGSCQVPLAAHARWDGDQLRLEAFVALPDGSRAIRAAAAGPAADLAA
AEALGQACAGDLLAQGAESILAALADSGDAASPSPA
>B9LRV4|hydroxymethylbilane synthase|EC 2.5.1.61|Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)|TrEMBL
MTDTLRLATRGSDLALRQAGTVRDALSSRRRDVELRRVETRGDQIPDEMIHRLGKTGAFV
RALDEEVLGGDADLAVHSLKDVPTEGMDDMVIAGVPERAPSGDVLVHPDGLGIEDLPSGS
VVGTGSLRRTAQIKAARPDLVVEPLRGNVDTRVEKLLAPDLQAEHERRLIASGEASAATA
EGSDDDDADDESADADEIDEEFDRTVEEWFDSLSDLERSAMERKVETEYDAIVLAEAGLR
RSELFYEVPTTRLPREEFVPAAGQGAIAVTATDPDVIEDVRSAVDHPRTRVAVTVERTIL
GELNGGCVAPIGVSALVQGEHVHTRVRVLSTDGTEEVADTRDLPIRSHAKAAEEFAADLA
DRGAAELIEAAREETRADEEADTDE
>E8S8Z5|hydroxymethylbilane synthase|EC 2.5.1.61|Micromonospora sp. (strain L5)|TrEMBL
MTAPLRLGTRGSALAMAQSGHVAEALTAATGRPVELVEVVTAGDRSTAPVQRLGVGVFVS
ALRDALTAGEIDFAVHSYKDLPTAAAPGLHVAAVPPRQDPRDALVATNGRTLAELPPGAR
VGTGALRRIAQLHALGMQLEVSPIRGNVDTRLGRVLGPDADLDAVVLARAGLNRIGRADV
ITETLDPMLMLPAPAQGALAVECRADDQDVIELLALLDHAPSRAAITAERALLATLEAGC
SAPVAAYAVLAEGEPTDEGDVNQEIYLRGAVISPDGTRDLRLSRTGTPADAAEIGKALAA
ELLELGADSILGQDAQAGPGTQQLGSTE
>H7XZ84|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 23264|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIVSLRGNVNSRIEKLKNNKFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILKLLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>G2URY4|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis NCGM2209|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>G2URY4|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis NCGM2209|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>H8AEM2|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1997-4|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>I0QQG7|hydroxymethylbilane synthase|EC 2.5.1.61|Serratia sp. M24T3|TrEMBL
MLDKTIRIATRQSPLALWQAQFVQSQLKAFHPDLQVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPVDFPKGLGLVTICEREDPRDAFVSNHFASLDDLP
QGSVVGTSSLRRQCQLRQQRPDLQIRDLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLD
SRVRAALTPEECLPAVGQGAVGIECRLDDVRTRELLAPLAHVETTLRVAAERAMNMRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMVRGERRGPTSEAESMGISLAEELLNAGAR
EILQEVYQGNAPK
>B1YUR6|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia ambifaria (strain MC40-6)|TrEMBL
MWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELENALADGRAD
LAVHSLKDVPMALPDGFALTAIMEREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAML
RARYPHLDVLPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLEARIRTLIDVEDSPPAA
GQGALGIEIAAHRTDVAAWLAPLHDPKTALAVEAERMVSRALGGSCEVPLAAHAVWRAGE
LYLTGRVSTTDGQRVLTAEECGAVMTIADALALGRAVSDELEAQGALDIVNALLAASQAG
KGDA
>I0C522|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 71193|TrEMBL
MNMRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKG
LFVKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLP
EGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWS
DDIVTSYLDRDTLLPAIGQGALGIECRSDDDELLSLLSKVHNDEVAKCVTAERTFLAEMD
GSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAY
EIIKRLNEQH
>Q1BE86|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium sp. (strain MCS)|TrEMBL
MSNADTPIRIGTRASLLATTQAGTIRDALIARGHAAELVLISTEGDRNQGPIADIGVGVF
TAALREAIHDGRVDAAVHSYKDLPTAADERFTIPAIPRREDPRDALVARDGLVLGELPAG
STVGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVGNGELDGIVVARAGLARIGRLGD
VTETLEPVQMLPAPAQGALAVECRAGDTGLIALLAELDDADTRAAVTAERVLLAELEAGC
SAPVGAIAEVVESIDEDGRVFEEVSLRGCVAALDGSDVIRASGIGTPGRAADLGVSVAAE
LFELGARELIADHH
>I2WCR2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 9.0111|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>E8AAR2|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 413180|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I0ETH4|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter cetorum (strain ATCC BAA-540 / MIT 99-5656)|TrEMBL
MEKLLIGSRGSELALWQANYIKQRLKTECSIESEIKIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLSGEIDLAVHSLKDVPVVFENELDLACITKRADVRDTFLSVKYPNLLSLPKGA
KVGTTSLRRSMQLKFKRKDLDTESLRGNVQTRLKKLELGVFDAIILAEAGLQRLEIKGAN
YRKAFSVNEMIPSMGQGALGVEMLKSHKHFSTLQKLNDEKTAFCCHLEREFVKALNGGCQ
IPIGVHASLIDDEVKIQAILGLPNGEQVISKEKQGDKAKAFMLVKELLEEFIASGAREIL
DKAQLF
>H8KEA8|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia parkeri (strain Portsmouth)|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKVSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>Q0RS16|hydroxymethylbilane synthase|EC 2.5.1.61|Frankia alni (strain ACN14a)|TrEMBL
MTAMEPTSTETDPTALGATLRARFAGRRLRLGTRRSALALTQSGMIAAQLRERVGCAVDL
VPIVTAGDRSPAEISQIGGTGVFVSALRDALLAGEIDLAVHSLKDLPTATPPGLVLAAVP
TREDTRDVLVSPSGRGLAALGPGARVATGAPRRAAQLRALGLGFDVVAIRGNVDTRLKKA
IDGEVDAVVLAYAGLARLDRLDAVTEILDPEVMLPAPGQGALAVECAAEAGLRLAGPARA
LVAAGAGDHADGDRPGAEAGRDGRGRGPDVGRNSGQTRSDHGQPLDGGLAELLRFVLDDA
SSSVAIRAERAFLAGIEAGCTAPVGALAVAEPAPAAAVGTVAPAGDASPAGRLRLRAVVA
APDGSTVLRRDVTGSAVDPEALGQRLADDLLSAGAHSLMGIR
>C5VPC7|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum D str. 1873|TrEMBL
MRIVVGSRGSKLALTQTNWVIDKIKQNNPQLNFEIKIISTKGDRIQHMLLDKIGGKGLFV
QEIEEQLISGQIDLAVHSMKDMSTDIPEELKFSYVPIREDYRDVLILNKKYKSIDELPKG
AKIGTGSKRRKYQLLDYRTDLKVVPIRGNVDTRIKKIETENLDGIVLASAGIKRLGLEDK
IDYNIFYLEKDIMLPSPAQGILALEIKRGRKDLENILKSIEHKASTIQAEAERAFLKGVN
GGCHVPIGALCNINKNTIEVTGLLGKEDGSKIIRKTLVGSIDEAEYVGYELAKIILKEIN
>H4CMF8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIGC345D|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>C7DBP9|hydroxymethylbilane synthase|EC 2.5.1.61|Thalassiobium sp. R2A62|TrEMBL
MSDFSDRTKHVVMTLTLPTPQSPLNIGTRGSPLALAQAYETRARLSAAFDLPSEAFTIVV
IKTTGDRIIDRPLKEIGGKGLFTREIEDAMLQGDIDIAVHSMKDMPVLQPDGLLIDTYLP
REDNRDAFIALDGSGLKDLAEGATVGTSSLRRHAQLMNRRPDLNIVEFRGNLQTRLKKLG
DGVAEATFLAMAGLNRLKMDDVPRTAIETDDMLPAVAQGAIGIERRADDSRMAEMLEAIH
DGPTGQRLAAERAFLKALDGSCETPIAGLAELNGGILYLRGEVLRVDGSDTVYDAASGPI
EDGAEMGRVMAAKLLAEAGEGFFDWR
>Q83FJ3|hydroxymethylbilane synthase|EC 2.5.1.61|Tropheryma whipplei (strain Twist)|TrEMBL
MYPLRIGTRSSLLATAQTAQVQKTMRDVFLLDTQQVLIQTGSVRRRDGSFVAALRTALLE
GECDLAVHSLKDIPIAPHEGTLITAVLPREDPCDVLCARKDLTLTTLPSGAKVGTASARR
RAQILNFRPDLDVVSLRGNIDKRLIHLDTLDAIVLSAAGLKRIDREDAITESFDIHDWPT
AAGQGSLAIEVCRAQLDDPQNRVAVTYRLDNPMARVTTTAERGVLSLLQADCFSPIAVHA
VYTANDKSLGLHAKVFSRDGKIFCESIRFARLVKQLTDTNQNHTKNSGSDDIGNALEVAM
TLAKTVVDELLSKNAREILKQ
>I4FLT2|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 9717|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGILDRSIDLAVHSLKDLPTKLPEGLILGCVTERVNPADALVVNSENQD
YQLDTLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDADPEVLEVLKVLEHAPSRDRCYAERA
FLRELEGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VREAGAGEILAQIFTEVGR
>C2M5U4|hydroxymethylbilane synthase|EC 2.5.1.61|Capnocytophaga gingivalis ATCC 33624|TrEMBL
MAVIRKKMKKTLRIGTRDSELALWQAKKVQTLLENFGYTTSLVPVKSQGDLSLDIPLYEM
GITGVFTKVLDVAMLQGSIDIAVHSMKDVPTSLPKGIVKGAVLTRANVQDVLVYKDGLDF
LSQEQATIATGSLRRKAQWLRRYPTHQVENLRGNIATRLHKLHEHSWHGAIFAAAALERL
AQDHLQRLSLEWMTPAPAQGAILAVAMDSDPYTLEALSLINDPKADTETQIERRFLKRLE
GGCTAPIGAKATLEGDTLSFVGNLFSLDGKQAVEVRKSIPTHSIGSFPEDCAQELLHSGG
EGIMQEIRKVMNIQK
>C2LYB8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus hominis SK119|TrEMBL
MRKLVVGSRRSKLALTQSKQFIDKLKAIDPSLEIEIKEIVTKGDRIVNQQLSKVGGKGLF
VKEIQNELFNNDIDMAIHSLKDVPSIIPEGLTLGCIPDREIPFDAYIAKNHVPLEELPKN
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLNKLETEDYDAIILAAAGLKRMGWSDD
VVTTYLDKDTLLPAIGQGALGIECRSNDIELLELLQKVHNNEVANCVTAERTFLASMDGS
CQVPIGGYANYNNNNEIEFTGLIMTPDGKERYEHTEVGTDPVKLGNRVSEILKEQGAYEI
IRKLNEEASH
>B4BQC9|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus sp. G11MC16|TrEMBL
MRNIVVGSRRSKLALTQTNWVINELKRLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLF
VKEIEHEMLTGGIDMAVHSMKDMPAVLPSGLVIGSVPRREDVRDVLVSKGNLSLSDLPSG
AVIGTSSLRRSAQLLAYRPDVTIKWIRGNIDTRLAKLKNEDYDAIVLAAAGLARMGWSDD
VISEYLSPDVCVPAVGQGALAVECREDDVELREWLSRLNDEQTERAVRAERAFLQQMEGG
CQVPIAGYAEVKEGMVHLTALVASPDGKEKYKEIVIGADPEEVGRQAAALLSEQGAKELI
ERVKKELGN
>E2PRH9|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella sp. BO2|TrEMBL
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDALLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>G3A0H6|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia syzygii R24|TrEMBL
MSSNARPTSVESPLAAQAPTQLVIASRESRLAMWQAEYVRAALQKYYPACDVSILGMTTR
GDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMELPAGFALPTILEREDP
RDAFVSNHYADLAALPAGAVVGTSSLRREASLRARFPHLVIRPLRGNLDTRLSKLDRGDY
AAIILAAAGLKRLGLSERIRAVIAPEASLPAAGQGALGIEIRADRPDVQAWLAPLHHPPT
ALAVTAERAVSRRLGGSCQVPLAAFAQWTDAGALRLRAFVASPDGRRKLAAESETAPATL
AEADALGASVAQQMLDGGAHDILATLGADAPPAT
>I6GGN7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EPEC C342-62|TrEMBL
MVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICE
REDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALN
HHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAP
QNAEQMGISLAEELLNNGAREILAEVYNGDAPA
>H0HDI4|hydroxymethylbilane synthase|EC 2.5.1.61|Agrobacterium tumefaciens 5A|TrEMBL
MQTKPFRIGTRGSPLALAQAYETRNRLMSAHGLPEDMFEIVVLSTKGDRITDRALSEIGG
KGLFTEELESQLLSGELDIAVHSSKDMPTVLPKGLYLSAFLPREDMRDAFIGRTAPKLLE
LPQGAVVGSASLRRQALIRRLRPDLSVIIFRGQVETRLRKLEEGQADATLLAFAGLKRLG
MENVPTDILDPKEFPPAPAQGAICVESRIGDTRMDELLSPINDIPTYDAVTCERAFLAAL
DGSCRTPIAGFATCHGEELHFSGLILTPDGQTSHSVEISGARKDAEDLGRRAGEDVRARA
GSNFFDGWS
>H8N3L1|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia prowazekii str. Chernikova|TrEMBL
MINSIRIGTRNSTLALIQTNLVIEQIKQIFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGKIPVELVIAAVLEREDPRDVLVCLNYQSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDAIILSYAGLKRLNVFN
QKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPERAFLEYLDA
NCSTPIAAYAQYLDAYNIQIDFMLGNLDCTKIIFQTEITNIKTSKICGIKAAKMMLAQQ
>I0LCL7|hydroxymethylbilane synthase|EC 2.5.1.61|Micromonospora lupini str. Lupac 08|TrEMBL
MTAPLRLGTRGSTLAMAQSGQVAEALTAATGRPVELVEVVTAGDRSNAPVHRLGVGVFVS
ALRDALTARTIDFAVHSYKDLPTAGAPGLHIAAVPARQDPRDALIAQGGRTLAELPPGAT
VGTGALRRIAQLHALGLQLEVTPVRGNIDTRLARVLGPDADLDAVVLARAGLARIGRTDV
ITETLDPMLMLPAPAQGALAVECRADDQDLVELLGTLDHAPSRYTVTAERALLATLEAGC
TAPVAAYAELAEGDAGDEIYLRGAVISPDGTRDLRLSRTGTPADAAEIGKALAAELLELG
ADSILGHQGHTGPGTQQFGSTE
>I0LCL7|hydroxymethylbilane synthase|EC 2.5.1.61|Micromonospora lupini str. Lupac 08|TrEMBL
MTAPLRLGTRGSTLAMAQSGQVAEALTAATGRPVELVEVVTAGDRSNAPVHRLGVGVFVS
ALRDALTARTIDFAVHSYKDLPTAGAPGLHIAAVPARQDPRDALIAQGGRTLAELPPGAT
VGTGALRRIAQLHALGLQLEVTPVRGNIDTRLARVLGPDADLDAVVLARAGLARIGRTDV
ITETLDPMLMLPAPAQGALAVECRADDQDLVELLGTLDHAPSRYTVTAERALLATLEAGC
TAPVAAYAELAEGDAGDEIYLRGAVISPDGTRDLRLSRTGTPADAAEIGKALAAELLELG
ADSILGHQGHTGPGTQQFGSTE
>H5BHA5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC9A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D1C4S0|hydroxymethylbilane synthase|EC 2.5.1.61|Sphaerobacter thermophilus (strain DSM 20745 / S 6022)|TrEMBL
MTIVPSPQLQVRLGTRGSALAREQTRRVMAALAALRPDLELIETIVSTAGDRDKRTPLTV
IGGQGVFARELQTALLAGTVDVAVHSAKDLPTEPVPGLVIGAFFSREDARDVLVSRDGRS
LADLPPGARVGTSSRRRLVALRRLRPDLEAVDLRGNLDTRLRKVREGEVDAAILAAAGLL
RMGWQEHITEFLSLDDFVPAPGQGALAIECRADDPAVNEMLAALNDPAAALAARTERSFL
RALGGGCRSPIGAHATVSGDTVTLRVMLGDEAMTRVRLSTWTLPAAEAETRAGALAVEVQ
RSLAGADPLPV
>B2J470|hydroxymethylbilane synthase|EC 2.5.1.61|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MRVNLSPCLIYCFMTSVVSSPPRTIRIGSRKSQLALVQTYWVQEQLQKSFPDITFEVHTM
STQGDKILDVALAKIGDKGLFTKELEVGMLNQEIDFAVHSLKDLPTNLPEGLTLAAITER
ENPADALVVHEKHKDKQIDTLPEGAVIGTSSLRRLAQLRHHFPHFTFKDVRGNLITRLAK
LDAGEYDALILAAAGLERLGMSDRVHQIIPKEISLHAVGQGALGIECRADDSELLTLLKA
IEHPATRDRCLAERSFLRSLEGGCQVPIGVNTEISGENLTLTGIVASIDGQKLVKDTVTG
IANNAEALGTELAELLRQQGAQEILSEIFAVIQRGS
>E6B0T2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 3431|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C8XF53|hydroxymethylbilane synthase|EC 2.5.1.61|Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104)|TrEMBL
MSSRVLRVGTRGSALALAQSGMIADRVARLAGATVELVRIRTEGDVNTGPLATIGGTGVF
VTGVREALLDGRADIVVHSYKDLPTAPTEGITVAAVPERESPFDALCARDGLRLDDLPRG
STVGTGSPRRAAQLLARRPDLAVVPIRGNVDTRLRQVSEGHLDAVVLAAAGLNRLGRADA
ITDVLDADRMLPAPAQGALAVECRSGADTWFTEATRTLDDAPTRAAVVAERVLLRDLEAG
CSAPVGAFAQVQGDALTLRAVVVAVDGSSEFRVHRAGSPAAAADLGARAAADLIGQGAAG
LLGAR
>E3I377|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodomicrobium vannielii (strain ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299)|TrEMBL
MKNHSDARQIRIGTRGSALALAQATEVQNRLAAIYGDEVKFERVVIKTTGDKILDKALSL
VGGKGLFTKELEEALFADQIDIAVHSMKDVQAFLPDGLEIACNLPREDVRDAFISMKAKS
LADMPEGAVIGTASVRREAFIKNKRPDLKTVLFRGNVQSRLKKLEDGVADATLLASAGLN
RLGLSDRITQHIPVEDMLPAPAQGAIGIEIRSNDQVTRELIMALHDEATGYAIDAERAFL
SELDGSCRTPIAALARYDGHGRVSFKGAILTPDGARIYETTREGSANDAAAMGKDAAQEL
YARGGKDVFPPAA
>C5N694|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus USA300_TCH959|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>A3XCC0|hydroxymethylbilane synthase|EC 2.5.1.61|Roseobacter sp. MED193|TrEMBL
MTQNLPSPASPLKIGTRGSPLALAQAYETRRRLAEAFDLPHEAFEIVVIKTSGDNQALIA
ADKPLKELGGKGLFTKEIEEDLLSGAIDIAVHSMKDMPVAQPEGLLLDCYLPREDVRDAF
VSPKFSRLQDLEPGAVVGTSSLRRRAQLMNRRPDLKVVEFRGNVQTRLKKLNEGVAECTF
LAMAGLNRLAMADVPATAIETNDMLPAVAQGAIGIERRGDDSRTAAMLEAIHDVTTGKRL
AAERAFLAALDGSCETPIAGLAELDGGTLRLRGEVLRPDGSEALAEDQSCAIEDGGELGR
EMAAKLLATAGPGFFDWRA
>C6TVP4|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei 1710a|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>C2JI53|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae BX 330286|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>I3DF33|hydroxymethylbilane synthase|EC 2.5.1.61|Fusobacterium necrophorum subsp. funduliforme ATCC 51357|TrEMBL
MLKHHIILGSRGSILALAQTNWVKKQLQRHYPQLTFSIQVIETQGDKDLTSHFGNSELSL
KSFFTKEIEKSLLDGEIDIAVHSMKDVPSSSPVGLICGAIPVREDVRDVLVSTSGKTLAD
LPKGSILGTSSLRRIQNIKQLRPDLEIKALRGNIHTRLKKLEEGHYDAIVLAAAGLKRVG
LEEKITEYLNPTVFSPAPAQGALYIQCREKDEETRNILQSIHDENLAKILEIEREFSRIF
DGGCHTPMGCYSKVEGKKIFFHAMYSHKEKSYQTIITESITKGKEIAIMAAQEIQKMMKE
K
>D0B3D9|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)|TrEMBL
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDVLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>I4D534|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfosporosinus acidiphilus SJ4|TrEMBL
MKKIRIGTRDSQLAMWQAEWVKHRLEQLHPHLSFELVPMKTKGDKILDVPLAKIGDKGLF
TKELEHGLLNNQLDMAIHSLKDLPTMLPEGLEICTFCEREEPRDVFLSKKGILLEELPEG
ALVGTSSLRRKSQLKHYRPDLCFTDLRGNLQTRWRKLQESEMDGIVLAAAGVKRLGWEER
ITQILSEDLVLSAVGQGSIAVEIAQQRDDIRGLLAPVNHPETELAVRAERMLMRKLEGGC
QVPIGALGQVTDGKIFLKGMVSSLDGNRLLKAEGRGTDPESVGIEVADQLLSLGAAEILA
EIR
>G9TMP5|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. ATCC BAA710|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I5GAB6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA5|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>H8IA26|hydroxymethylbilane synthase|EC 2.5.1.61|Methanocella conradii (strain DSM 24694 / JCM 17849 / CGMCC 1.5162 / HZ254)|TrEMBL
MRIGTRGSRLAMAQADKVCRMLRERGIDAEPVVIKTSGDIHTSEPLHVIKGGVGAFVREI
DEFLLNGEVDAAVHSLKDVPTKRPPGLATAAVLRRESALDVAISRSGERLSELKEGAVVG
TSSTRRAALIKRHYPGLVTKNIRGNVDTRLRKLRDGEYDAILLAEAGLIRLGISLPVERL
DPYEFVPSANQGVIAVVARPGTAAFEAASALNDFDTWLETRVERLITSALDGGCVVPMGA
YARRAGDDLDVVCEVLSLDGRRQARVRERIPVDGYEAHAMRLAESLAANGGKELVEEAKR
ELKG
>H8AC30|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 2008-831|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>A8PKX6|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsiella grylli|TrEMBL
MSKKKFLRIATRKSPLAYWQATSIKNQLEKIFPFLKITLLPFVTEGDRPSHSLNQWGGKG
LFVKELEAALLHGQADIAVHSLKDLPMTLEKGLVLGAICKRCDPRDVLISRSDRLFTQLP
PGSYVGTSSLRRQSQLLALRPDLKIGVLRGNIGTRLNKLAAGEFDAIILAAAGLIRLKKT
ECISEYFEIDHFLPAPGQGALGIECHENDEESLTYISALIHPITHSCVLAERALSRELGG
GCQVPLAAYAASLGQDFIRLQAFVGSSDGTTQIKVEKQGPRVEAEKIGFLAAQDLRALGV
EEILNKFKRIK
>H3V1I3|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU117|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>D4LSL4|hydroxymethylbilane synthase|EC 2.5.1.61|Ruminococcus obeum A2-162|TrEMBL
MVKTEVQNKVIIGSRESRLAVLQSEMVRDYIKTQHPELDVEILTMKTTGDKILDRTLDKV
GGKGLFVKELDKALLEGRTMLSVHSLKDMPMEVPGELPLLAFSKREDPRDVLVLPEGVSE
LDLTKPLGCSSLRRTLQLKELYPEMEVKSIRGNLQTRLRKLDNGEYSGLILAAAGLKRLG
LENRICRYFSEDEILPAAGQGILAVQGRQDLTYDYLEGYRDEKAWFAGSAERAFVKYLNG
GCSSPVAAYGVVEGDELFLRGLYYRECDGRYFKDSIRGPKSEAEKLGRDLAKRMQDMYEN
DKTGGTSL
>E6L8G0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter upsaliensis JV21|TrEMBL
MKKLIIATRKSPLALWQSEFVADILRKTHHIEVDLEGFSTKGDILLDSPLAKIGGKGLFT
KELENAMLENKAHLAVHSLKDVPSFLPQGLVLAALSVREDDTDALLSELYKDLNALPQNA
KVGTTSLRRKMQLLSLRPDLHIINLRGNVNSRLKRLKDGEFDAIILASAGVKRLGLESEV
KFIYRFSKDELVPAATQGILGIQSPNKSEILTLLQCLNDEKSLIESTVERDFIRTLEGGC
QVPIGINAELIGEQITVRSILGLPDGSEILRDKRIILKKNYQGFGERLALEFIKRGAKEL
LKRAEAML
>I6DJL2|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella boydii 4444-74|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDARTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>D1AUH9|hydroxymethylbilane synthase|EC 2.5.1.61|Anaplasma centrale (strain Israel)|TrEMBL
MYAPVVRLGTRGSTLALIQAEEVKAAIAAHFPEVRVDVTKIKTSGDVKVDRPLCDIGGKG
LFIKEIEEALLANKIDIAVHSAKDVPGFYSENLDMPCVLKRRSPMDVFISVKYKSLNSLP
AGAKIGTSSIRRKVQLLAFRPDLEITPMRGNVDTRIAKVQSGECDGIVLAEAGVDRISAR
AKITEVLHPDVMLGAVGQGAICVQCRKSDEGIVRMLAKLNDHESFTAVLAERSFMKAVNG
SCHTPLAAMARYVDSGLMSMKCMLAHDSRTMVSAERTFPERDAESVGFEMGVMLKDELRL
RGV
>I4L8Q0|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas synxantha BG33R|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLKVSLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTYASLDDLP
LGSIVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVEDSLPAGGQGAVGIECRTVDSEIHALLKPLDHADTEVRVTAERALNKHLNG
GCQVPIACYAVLEGESLWLRGLVGDPDGGTLLTAQVRGPQRDATALGIQVAEELLDKGAG
AILQKVYGEAGPQ
>F0NQ41|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain HVE10/4)|TrEMBL
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIINIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLERDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNEDIIP
>H4NW42|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC3E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E8UE86|hydroxymethylbilane synthase|EC 2.5.1.61|Taylorella equigenitalis (strain MCE9)|TrEMBL
MVLSIKNLRIATRESRLAVWQAEFVQKKLKSIFPHLNVELHKMTTKGDQILDKTLSKIGG
KGLFIKELESSLLSGVTDLAVHSLKDVPVELNDEFEIACILERENPMDAFVSNEYKTFKD
LPEGAIVGTSSLRRESQIRAKFPHLVVKPLRGNLDTRLKKLDDGQYSAIILAAAGLKRLN
MMDRIKSFVSIDDSLPAVGQGALAIEILKDKFALKEMLSYLHHEETFKCVSAERIVSQYL
GGSCQVPLAAHACVINDLFQVRALVASPDGSRILRAESFGSPDEYESVATTVALNLIDQG
AREIINASLGIDE
>D7FFC6|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain B8)|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECFIESEIQIVKTTGDKILDAPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADARDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLNVQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPVGVHANLMGDEVKIQAVLGLPNGKEVITKEKQGDKNKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>D5AX59|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia prowazekii (strain Rp22)|TrEMBL
MINSIRIGTRNSTLALIQTNLVIEQIKQIFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGKIPVELVIAAVLEREDPRDVLVCLNYQSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDAIILSYAGLKRLNVFN
QKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPERAFLEYLDA
NCSTPIAAYAQYLDAYNIQIDFMLGNLDCTKIIFQTEITNIKTSKICGIKAAKMMLAQQ
>I4SR20|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli KD1|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGIALAEE
LLNNGAREILAEVYNGDAPA
>G6Y5Q3|hydroxymethylbilane synthase|EC 2.5.1.61|Mesorhizobium amorphae CCNWGS0123|TrEMBL
MAIVVAGTAERLIKAVEPRIEVEICPFVSEGDLIKGDLKLYGGKGTFIKDLERRLLANEI
DCAIHALKDIPGDVQMHEELMLIAFLSREDPRDALVLRSGLSEEEFLAKQRVRIGTSAPR
RRAAALRLFPDCAVELSRGNVNTRLKNLDSGLHDALILSGSGLDRVGFHSRIARLFSYDE
VLPAAGQGILVLQIRREDLNRCSYLRIVNNEESENAAAAEREVLAQLNGNCHSAIAAHCW
AVESGGHKLTAAVFDSATGNCLEAAMELPLNSKDFTELGAKVAEQLIKDGCRKFLTPVGA
>I5WL84|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4436|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I5TTD6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW14301|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C6R3Y0|hydroxymethylbilane synthase|EC 2.5.1.61|Rothia mucilaginosa ATCC 25296|TrEMBL
MSHHEYTLGTRGSALALTQSRIAAETVTSLYTEHQAHHGAENPEAVSFELRTVKTEGDVL
TGPLATLGGTGVFAAALRQRLLDGENASEENRVDMAVHSLKDLPSAPCPGLVVAATLKRE
DPRDALVARDGLTVDTLPEGSRVGTGSPRRAAQLRALRPDLEIVDVRGNVGTRIGRVKGL
EEHAGKQVVLRQNAETSERADHGVGTERSGDCDAVVLAVSGLKRLGKEELITEYLDPTRM
LPAPGQGALALEVRESEFENPDSAVLADPEVARPVRALGRALLAANHHETRLAVSAERAL
LRRLEAGCAAPIGAYAHVVEGDLVLNVVVASPDGTDMLRHTSATAELDVPGAERLGVRVA
EDLLQMGAAALAGLDLK
>C6R3Y0|hydroxymethylbilane synthase|EC 2.5.1.61|Rothia mucilaginosa ATCC 25296|TrEMBL
MSHHEYTLGTRGSALALTQSRIAAETVTSLYTEHQAHHGAENPEAVSFELRTVKTEGDVL
TGPLATLGGTGVFAAALRQRLLDGENASEENRVDMAVHSLKDLPSAPCPGLVVAATLKRE
DPRDALVARDGLTVDTLPEGSRVGTGSPRRAAQLRALRPDLEIVDVRGNVGTRIGRVKGL
EEHAGKQVVLRQNAETSERADHGVGTERSGDCDAVVLAVSGLKRLGKEELITEYLDPTRM
LPAPGQGALALEVRESEFENPDSAVLADPEVARPVRALGRALLAANHHETRLAVSAERAL
LRRLEAGCAAPIGAYAHVVEGDLVLNVVVASPDGTDMLRHTSATAELDVPGAERLGVRVA
EDLLQMGAAALAGLDLK
>D0KC07|hydroxymethylbilane synthase|EC 2.5.1.61|Pectobacterium wasabiae (strain WPP163)|TrEMBL
MLANIIRIATRQSPLALWQARYVQQRLNHLYPDLSVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPVEFPDGLGLTTICERDDPRDAFVSNHYDSLDQLP
QGSCVGTSSLRRQCQLRARRPDLVIRDLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
ERIRCALSPEESLPAVGQGAIGIECRLDDDRIRQLLAPLNHTDTAARVLAERAMNVRLEG
GCQVPIGSYAELEGNTLWLRALVGAPDGSQMIVGERKGSVVDAEKIGIALAEELLAKGAS
AILQAVYQGSSSS
>D1WMW6|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis SK135|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>A9BYX7|hydroxymethylbilane synthase|EC 2.5.1.61|Delftia acidovorans (strain DSM 14801 / SPH-1)|TrEMBL
MNTKPLLPHSIVIATRESQLALWQAEHVQALLRARGHEVELLGMTTKGDQILDRTLSKVG
GKGLFVKELEVALEEGRAHIAVHSLKDVPMELPEGFVLACVMEREDPRDAFVSNRYATLA
ELPQGAVVGTSSLRRQALLQALRPDLKIEPLRGNVNTRLRKLDEGHYDAIVLAAAGLMRL
GLADRIRARFEPTGMLPAAGQGALGIEVRADRQDLIDALAPLAHQTTWLTVTAERAVSRC
MGGSCSMPLAAHGTFDGRQLRLDAAWGDPQGRLPLVQVHADATVTDFASADALGQHVAAL
LQAAGAQPAPKL
>H5NGP2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC14B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B3ZNQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus 03BB108|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>F4DYQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas mendocina (strain NK-01)|TrEMBL
MSREIRIATRKSALALWQAEYVKARLEQAHPGLKVSLVPMVSRGDKLLDAPLAKIGGKGL
FVKELETALLENEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTYDSLDALPA
GSVVGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFAD
RIRSSISAEDSLPAGGQGAVGIECRSADSDVHALLAPLHHRETALRVTAERALNKHLNGG
CQVPIACYALLEDDQLWLRGLVGQPDGGLLLRAEERAASGDAEALGVRVAEALLAQGADA
ILKAVYGEAGHP
>D7E031|hydroxymethylbilane synthase|EC 2.5.1.61|Nostoc azollae (strain 0708)|TrEMBL
MTSVFSPPRPIRIGSRKSQLALVQTYWVQEQLQKSFPNITFEVHTMSTQGDKILDVALAK
IGDKGLFTKELELRMINKEIDFAVHSLKDLPTNLPEGLTLAAITERENPADAVVLHKKHK
DQQIETLPAGAVIGTSSLRRLAQLRYKFPHFTFKDVRGNLITRIGKLDAGEYDALILAVA
GLERLDMSHRIDQILPPDISLHAVGQGALGIECRSDDTEVISLLKAIEHSQTRDRCLAER
SFLRVLEGGCQVPIGVDTQINSKELTLKGLVASVDGQKLVKDTVTGTAADAEKLGAQLAR
ILRQKGATEILEQIFTEIQRGS
>F3GJA0|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. pisi str. 1704B|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDQLP
AGSIVGTSSLRRQAQLLARRDASFARSQKHYYQAPPQIERGWRNHLIDMQGRSYLDMLNN
VAVLGHGHPRM
>A1TNP5|hydroxymethylbilane synthase|EC 2.5.1.61|Acidovorax citrulli (strain AAC00-1)|TrEMBL
MHPSPPPTTSAASGLPPIVIATRESRLALWQAEHVQALLRARGHAVELLGMTTQGDRILD
RTLSKVGGKGLFVKELEVALEEGRAHVAVHSLKDVPMELPEGFELACVMEREDPRDAFVS
PRHACLADLPQGAVVGTSSLRRQVLLQALRPDLVIQPLRGNLDTRLRKLDEGQYDAIVLA
AAGLKRLGLEGRIRALFEPDEMLPAAGQGALGLEVRSERHDLLQAVAPLAHQATWLCVAA
ERAVSRALGGSCSVPLAAHGRWTDAGTLRLDGAWGDPEGIRPLVRVQISAPVASLPEAEA
LGSAVAARLRADGAQIPA
>H4T0F0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC5B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H4LMC2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC3A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q5LMB4|hydroxymethylbilane synthase|EC 2.5.1.61|Silicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)|TrEMBL
MKIALPSPASPLKIGTRGSPLALAQAYETRHRLGAAFDLPEDAFEIVVISTTGDNRAMIE
ADRPLKEIGNKGLFTKEIEEAMLRGDIDIAVHSTKDMPVEQPAGLVLDTFLPREDVRDAF
ISPGHSAIRDLPLGAVVGTSSLRRKAQLLNRRPDLKVVEFRGNVQTRLRKLSEGVAECTF
LAMAGIRRLNMAEVPATAISPDDMLPAIAQGAIGIERRMDDTRAAEMLTAIHHGETGQRL
AAERALLAALDGSCETPIAGLAELDGTTLRLRGEVLRPDGSEAITLDRSGDVADGPALGT
EMARELLAQAGPGFFDWRG
>A4CRY6|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain WH7805)|TrEMBL
MALEHLRIASRRSQLAMVQTNWVKAELESAHPGMAISVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGRAEIAVHSLKDLPTNLPEGLMLGCITEREDPADALVVNSKNADHTLE
TLPEGSVVGTSSLRRLAQLRHHFPHLQFKDVRGNVITRLEKLDAGQYDCLILAAAGLSRL
GFGDRIHQIIPGHISLHAVGQGALGIECVCDRPEVLKIIQVLEHAPTAGRCLAERAFLRE
LEGGCQVPIGVNSRIDGQELILTGMVASLDGLRLIRDERRGSLTDPEAIGRALAADLKSR
GAGEILQEIFEAVRPEA
>E1UGR4|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 4a (strain L99)|TrEMBL
MKRKIIVGSRRSKLALTQSNWVINKLKENYPAFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDKTIDFAVHSMKDVPSSLKEGLVIGAIPKRESPLDCFVFNQVNALDELPH
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATKANEAVHFKGLVGNADGSIILEAEQTGANPSEIGNKVAEDLLSKGAD
TIIQELRNI
>H0DS47|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU071|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKLIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLQTEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTVLGTDPVKLGKEVSQVLKKQGAYDI
IKKLNEAE
>H7U6F5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 1957|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>G4GIS0|hydroxymethylbilane synthase|EC 2.5.1.61|Natrinema pellirubrum DSM 15624|TrEMBL
MRTRGTLRLATRGSALARRQASLVKEALEERRYEVELVTVETTGDQIRDELIHRLGKTGA
FVRELDERVLEGDLDGAIHSMKDMPTEQPEALVTAGIPERGLPGDVLITPDGSTLEELPA
GATVGTSSLRRRAQLLSERDDLEVEPLRGNVDTRLEKLLAPSLQAEHQERSEADKERKGN
TGDDDFEAEYDRTTDEWFDDLSELERQALGREVETEYDAIVLAQAGLERSGLAHYVEYQE
LPTDTFVPAPGQGALAVTAPDGETAREIKSAIDHPRSRVETTVERTILAELGGGCIAPVG
IYAILQGEHVHATVTVFDQDGDESVTGSRDLPVDSHAEAAREFARDLADRGAAELIEGAR
EDAEGDDEGVSEEDKPEGK
>A5TVZ0|hydroxymethylbilane synthase|EC 2.5.1.61|Fusobacterium nucleatum subsp. polymorphum ATCC 10953|TrEMBL
MKKNIIIGSRGSILALAQANLVKEKLELNYPNLTFEIKEIVTSGDKDLKSNWENSDISLK
SFFTKEIEQELLDGDIDIAVHSMKDMPAISPKGLICGAIPDREDPRDVLVSKNGFLVTLP
QGAKVGTSSLRRAMNLKAVRPDFEIKHLRGNIHTRLKKLETEDYDAIVLAAAGLKRTGLA
DKITEYLNGEVFPPAPAQGVLYIQCRENDEEIKEILKSIHNEAIAKIVEIEREFSKIFDG
GCHTPMGCYSQINGDKIKFTAVYSDEGKQIKAVVEDYLVKGKEIAHMAAEEIKNKIAKNT
L
>I0A375|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Heidelberg str. B182|TrEMBL
MATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVHSMKDVPV
AFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRL
DDARTQALLAPLNHSQTALRVTAERAMNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPD
GSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA
>E9A8P2|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Weltevreden str. 2007-60-3289-1|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHS
LDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELL
ENGARAILTEVYNGETPA
>H6QDF5|hydroxymethylbilane synthase|EC 2.5.1.61|Pyrobaculum oguniense (strain DSM 13380 / JCM 10595 / TE7)|TrEMBL
MRLVVATRGSKLSLLQTEELLAQIKAVEPNIEFEIKIVKTTGDEIQDKPLYQIGVKGIFE
KEVNLAVLRGEADIAVHSLKDLPSELSPGLVVAGFSKRAPPFDALVSTAGYVLETLPRGA
LVGTSSVRRAEFIKAIRPDVRVEPLRGNVDTRINKILQGKYDAAIMAVAGIYRLYGASPP
IKLAVLRPEVLPPPPGQGIVAAVVKEADSWLIDLLKKASDPKAALEAIAEREFLKAVGAG
CHVAVGGVAFARNGTVEFIAGYASGGRKYIVRVVGDDPVEVGRRAAEEIRKFKDGGV
>H7RBH5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 2548|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>H6R3C8|hydroxymethylbilane synthase|EC 2.5.1.61|Nocardia cyriacigeorgica (strain GUH-2)|TrEMBL
MNASMTATTRSASDVRTPLRIGTRGSLLALTQAGTVRDALIAAGRPAELIVVKTPGDLSS
DPVEKIGVGVFTSALRDELAAGTVDIAVHSYKDLPTAPDERFTIAAIPQREDPRDALVAR
DGLVLGELPVGSVVGTSAPRRGAQLRALGLGLEIVPLRGNLDSRLRKVSEGELDAIVVAR
AGLSRIGRLDAVTEALEPVQMLPAPAQGALAVECRSDDTDLIELLTQLDDAATRAAVIAE
RALLAELEAGCTAPVGAIAEVVESLDDDGRIVEELSLRGCAAAIDGSDVLRASVVGAPAD
AAELGRALARELLELGARELLAAEPAPVAAAPTDVTDPSPMENNR
>A3THP4|hydroxymethylbilane synthase|EC 2.5.1.61|Janibacter sp. HTCC2649|TrEMBL
MTLRLGTRRSALATTQSGWVADQLRALGHDVELVEITTDGDRDRTTPLATMGGTGVFVSA
LRDALRAGTVDLAVHSLKDLPTTPEDDLAVAAIPPREDPRDALVARDGLTLGELPSGSTV
GTGSPRRRAQLEALGLGLDIRELRGNVDTRLGRVTSGDLDAVVLAQAGLARLGRTSVVTE
VIDPIQMLPAPGQGALAVEVRADDAATRDAVAALDDADTRACVDAERAVLSELEVGCSAP
VGALAEIVLGDDGDELSLRAVVASPDGTGDIRRSATGSPTDADGIGRRLARLLLEDGAAD
LAPVPSLSNGTTGTTVNTASTVHTERPGA
>A3THP4|hydroxymethylbilane synthase|EC 2.5.1.61|Janibacter sp. HTCC2649|TrEMBL
MTLRLGTRRSALATTQSGWVADQLRALGHDVELVEITTDGDRDRTTPLATMGGTGVFVSA
LRDALRAGTVDLAVHSLKDLPTTPEDDLAVAAIPPREDPRDALVARDGLTLGELPSGSTV
GTGSPRRRAQLEALGLGLDIRELRGNVDTRLGRVTSGDLDAVVLAQAGLARLGRTSVVTE
VIDPIQMLPAPGQGALAVEVRADDAATRDAVAALDDADTRACVDAERAVLSELEVGCSAP
VGALAEIVLGDDGDELSLRAVVASPDGTGDIRRSATGSPTDADGIGRRLARLLLEDGAAD
LAPVPSLSNGTTGTTVNTASTVHTERPGA
>F9BHI3|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-02A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDAILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDHIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>B8L8P2|hydroxymethylbilane synthase|EC 2.5.1.61|Stenotrophomonas sp. SKA14|TrEMBL
METVRIATRKSPLALWQSEHVADRLRQAHPGLHVELVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDAPFALPAMLTRHDPADGFVSNLYASLEALPIG
ARVGTSSLRRQAQLRALRPDLELLDLRGNVNTRLAKLDNGGYDAIVLAVAGLERLGLGQR
IVARLQPPQWLPAPAQGAVAVECDGGNARLMALFAGLDDASTRACVEAERAMNRALHGSC
HVPVAAIAQWQGDDLHLQGLVGSASDGRAVRAEAVGPASDPDALGQRVATMLLDAGAGEL
LNV
>I1YJA8|hydroxymethylbilane synthase|EC 2.5.1.61|Methylophaga sp. (strain JAM7)|TrEMBL
MKDALVRIATRRSPLAVWQAEFVRDALLAMHPHLTIELVKIKTKGDKILDTPLAKVGGKG
LFVKELEVAMQEGEADIAVHSMKDVPVAFPDGLHLPVICARHDPFDAFVSNHYANVDDLP
EGAVVGTSSLRRECQLRHYRPDLQIKPLRGNVNTRLAKLDAGEFDAIVLAKAGLERLEFH
DRIRCALTAEQSLPAIGQGALGIETRIDDAELNALIAPLACPDTTITVKAERALNRRLQG
GCQVPIGGYAVLEDGQIWLRGLVGRPDGSEMLFDDIQGAADQAEALGLTLADSLLAQGAD
AILSDVYDR
>D5DT75|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus megaterium (strain ATCC 12872 / QMB1551)|TrEMBL
MRKIIVGSRRSKLALTQTKWVIEQLKKQGLPFEFEIKEMVTKGDQILNVTLSKVGGKGLF
VKEIEQAMLDKEIDMAVHSMKDMPAVLPEGLTIGCIPLREDHRDALISKNGERFEELPSG
AVIGTSSLRRGAQLLSMRSDIEIKWIRGNIDTRLEKLKNEDYDAIILAAAGLSRMGWSKD
TVTQYLEPEISVPAVGQGALAIECRENDHELLSLLQALNHDETARAVRAERVFLKEMEGG
CQVPIAGYGRILDGGNIELTSLVASPDGKTIYKEHITGKNPVAIGSEAAERLTSQGAKLL
IDRVKEELDK
>B8IR20|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacterium nodulans (strain ORS2060 / LMG 21967)|TrEMBL
MVLRRQDMVHRPLRIGTRGSPMALAQTGMVRDRIAAAHPHLAEPGAMELVVVNTVADKVL
DRPLSAIGGKGLFTKELEQALFAGEIDLAVHSMKDVETWLPDGLVIASILERDDPRDAFL
SLKARSLAELPAGSRVGTSSLRRGAQVLMRRPDLQIVPLRGNANTRIRRLEEGACDATLL
AIAGLERLGLAHLAQEVMGTDTMLPAVAQGALGIECRAADQELIDLLQAVACPRTTTALA
AERGLLAELDGSCRTPIAALAEIEGDRLTLNGLLFLPDGSAHWATTRSGPAAEAAAIGKE
AGADLKAQAGETYRKHLQ
>I1ABF1|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa PADK2_CF510|TrEMBL
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSINVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAE
AILEAVYGEAGHP
>I6IP16|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis PY-36|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>D8GX75|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus var. anthracis (strain CI)|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGVPFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDDE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGIDPKEVGLEAADRLIKQGAKEL
ILAANKGQQ
>B1RPR0|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium perfringens NCTC 8239|TrEMBL
MELIIATRKSKLAQVQTEKVMELLKGKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVK
EIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGAR
IGTSSIRRAEQLKLFRDDLEIVPIRGNVQTRIKKITEENLDGIILAAAGLKRLGMEDVIS
DYFDPKVFLPAIGQGALGIECLKGGEFNDYFKALDSKEVRTTVEAERSFMKVLNGGCHSL
IGAYSEVKDNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILEEV
>G7EZN8|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas sp. BSi20429|TrEMBL
MTEKTKLVRIATRKSALALWQAEFVKAELERFHADVRVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLDGRADIAVHSMKDVPVEFPDGLELYTICEREDPRDAFVSNNFANLNE
LPQGAIVGTSSLRRQCQIKALRPDLDIRDLRGNVNTRLGKLDDGQYDAIILAAAGLIRLK
MSKRIADYIEPEVSLPANGQGAVGIECRIDDEVTKALLAPLEHTQTRIRVNAERSMNRYL
EGGCQVPIGAYALVDGEQVHLRGLVGAVDGSEILRDEVTGHVNDAEELGIELAKKLLAQG
ADKILAEVYRDA
>H3T0A8|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa MPAO1/P1|TrEMBL
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAE
AILEAVYGEAGHP
>F3UVA5|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK49|TrEMBL
MKVIKVGTRKSKLAITQTQQLVDQLKELHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISRREDVRDCLIFRQAGQTLADLPK
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRSLLAAVQDEKTAAEVAVERAVLAQM
NADCTFPIAAFAQKNGQDYQLEAMLAKEDGQCVFVSLQGQDGQELAEQAVRQLADKGAVG
MPWLKK
>E8HMY2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H- str. 493-89|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E1LBH6|hydroxymethylbilane synthase|EC 2.5.1.61|Veillonella atypica ACS-134-V-Col7a|TrEMBL
MRNHIRIGTRKSALALWQSEYVKSELQRLYPGITVELVHFNTKGDRILDKPLAEVGGKGL
FTAELEAAMHAGDIDIAVHSLKDMPTELPDGLTLGAISKREVPFDALVSPKYKTLDQLPE
GARIGTSSLRRQAQLLHRRPDLQIEVIRGNVQTRLGKIETEGLDGVVLAQAGLKRLGLDD
RITQVFTADEMIPAVGQGALAIECRSDDTEMLEILSKIDDEPTRLAVEGERSFLNQLNGG
CQVPMGVYGTVEKGQLILKALIASLDGKTVYEGELSGPAKKGVMLGKNLAKALYEEGGKH
IVEALVKEGIIK
>A2PX60|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae MZO-3|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVDDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGNTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>I3IFA9|hydroxymethylbilane synthase|EC 2.5.1.61|Cellvibrio sp. BR|TrEMBL
MSYSSSRPLRIATRKSLLALWQAEYVKAELEKHHPGLVVELVPLTSRGDKILDVPLAKVG
GKGLFVKELETALLEGDADIAVHSMKDVPMEFPAGLGLAVICPREDARDAFVSHRFASLD
ELPQGAVVGTSSLRRQCQLLAARPDLQIKFLRGNVQTRLQKLDDGEYDAIILAAAGLIRL
ELKDRIRAYIEPELSLPAGGQGAVGIECRMDDLAAIELLKPLHHSSTAEQVSAERAMNRH
LQGGCQVPIACYALHRNGQLWLRGLVGAPDGSQMLFDEITGPVAEAEQMGIALADRLLAA
GADKILAAVYADAE
>I4VJN3|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodanobacter fulvus Jip2|TrEMBL
MTTTLRIATRKSALALWQAEHVAALLRVAHPTVDVVLVPMTTRGDEILDKPLATIGGKGL
FLKELEVAMLEGHADLAVHSLKDVPADLEPGFTLPAILPRADAADAFVSNDYADLAALPQ
GARVGTSSLRRQTQLRALRPDLQLLDLRGNVGTRLGKLDTGSYDAIVLACAGLERLGLAS
RIRSRLAAPDWLPAPGQAAIAIEARDDHPRVLQLLAALDDPDTRVTVSAERAMNRALGGS
CTVPVGAWCVLGEHGLHLRGMVGDVERGRLLHAEAHATSDQAQALGEQVAEALLQQGAGA
LLGL
>Q0PIF2|hydroxymethylbilane synthase|EC 2.5.1.61|Heliobacillus mobilis|TrEMBL
MSVLQRPVVIGTRDSALALWQTNWVMARLKELFPEQAFEVKAIKTKGDKILDVALAKIGD
KGLFTKELEVSMLEGEIDMAVHSLKDLPTVLPEGLTIGAMCVREDCRDILISRHGGLDAL
PQGARVGTASLRRKAQIWQVRPDLELLDIRGNLQTRLRKMEEQNLDGLILAAAGVIRLGW
AEKISQY
>C7HGX4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium thermocellum DSM 2360|TrEMBL
MKIRVGSRESKLAVRQAQIVIDSIKKYNPDIEIELVTMKTTGDKILDKTIDKIGGKGLFV
KELDRALLDGKVDITVHSFKDMPMDIDDRLPIVAVSKREDPRDVLVLPKGKNEIDFNGPI
GCSSSRRKIQIEKIYPGCTVEPIRGNVLTRLEKLDKGEYSAIALAYAGLKRLGLEERIWR
VFSTDEIVPAACQGIIAVQARKDFDASILANFHDKDSWDVSVAERSFIKALNGGCSSPSA
AYGVIQGEKIVLTGFYVDKNGKIYKMTKTGDRNQGEALGYSLAMEMLKGADA
>I4N737|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas sp. M47T1|TrEMBL
MPTREIRIATRKSALALWQADYVKARLEQAHPGLTVTLVPMASRGDKLLDSPLSKIGGKG
LFVKELENALLDNEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTFNSLDALP
AGSVVGTSSLRRQTQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITDSISIEHSLPAGGQGAVGIECRTADTEIHALLAPLHHADTAARVSAERALNKHLNG
GCQVPIACYAVLEGDQLWLRGLVGEPDGARLLTADARAPRSAAEQLGIDVAEALLRQGAD
QILKAVYGEEGHP
>D5W4Q6|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia sp. (strain CCGE1002)|TrEMBL
MNTETFSTPPHTLVIASRESRLAMWQAEHVRCALHKLYPSCDVKILGMTTRGDQILDRTL
SKVGGKGLFVKELEAALADGRADLAVHSLKDVPMELPAGFALSTIMEREDPRDALVSNQY
DSLAALPAGAVVGTSSLRREAMLRMRYPHLDVRPLRGNLDTRLAKLDRGDYAAIILAAAG
LKRLGLADRIRALLDPEDSLPAAGQGALGIEIRADRADLAAWLAPLHHQHTAAAVEAERM
VSRALGGSCEVPLAAYATWGDGALHLRGIVATPDGQRVLSAQASAPAPTVERALALGEEV
AQSLAQQGALEIVRALSTASGPAAAPGAAASE
>E3D223|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup B (strain alpha710)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>H6CMR0|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus sp. Aloe-11|TrEMBL
MRTIVVGSRQSALALTQTGHVIEDLKSLCAEHGLALQFVVKKILTKGDRILDVTLSKVGG
KGLFVKEIEQAMLAGEIDMAVHSMKDMPSELPEGLVNGAVPRREDPRDCLITLGAKSLED
LPQGAKVGTSSLRRASQIKAMRPDLQLEPVRGNIDSRLKKLETEGFDAIILAAAGLHRMG
WKERITSYIPEEACLPAVGQGALGIECRADDEELLSLLRLYNDRDTSATVAAERTFLGVL
NGGCQVPIGAHAVWAGQEIRLTGMVGSPDGEVILKETLQGDDPQKLGEAVASSLIAKGAE
QILAQVRG
>C6UZU3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 (strain TW14359 / EHEC)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B8ZT70|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium leprae (strain Br4923)|TrEMBL
MAHVIRIGTRGSLLATTQAALVRDALIANGHPAELVIVNTAGDQSSASIDSLGVGVFTTA
LRAAIEEGCVDAAVHSYKDLPTADDPRFTVAAIPPRNDPRDAVVTRDELVLAELPAGSLV
GTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDEVTE
TLDPVQMVPAPAQGAIAVECRAGDSRLVAVLAALDDADTRAAVTAERVLLAELEAGCSAP
VGAIAQVVESIDGEGRVFEELSLRGCVAALDGSDVIRASGISTSGRASELGLAVAVELFE
LGARELMWGARSDRARGS
>H6RPM2|hydroxymethylbilane synthase|EC 2.5.1.61|Blastococcus saxobsidens (strain DD2)|TrEMBL
MTATDLQTTTAAAAGSSAPLRLGTRASVLARTQSQAVADALTAATGVPVELVLISTEGDR
SSASIAQLGATGVFVAAIRRALLDGEVDLAVHSYKDLPTAPEPGISLAAVPAREDPRDAL
VARDGLTLGELPPGSRIGTGAPRRVAQLRALGLGLEIVPIRGNVDTRLGRVAGSAGGPGD
LDAVVLARAGLSRIDRAHLITETLDPIQVLPAPAQGALAVECRSSDARTRELLGRLEDTA
VRACVVAERATLATLEAGCSAPVAAYAEIAEGETGPELFLRASVTALDGSDAVRGSLTRP
LADAAALGRALAADLLDRGAASLMAVGR
>H7ZPM0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 2008-872|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>H3YV38|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-111|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>F8JWK0|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057)|TrEMBL
MTATRSAQALRLGTRRSKLAMAQSGMVADQVARVTGRPVELVEITTYGDTSREALAQIGG
TGVFVSALREALLAGEIDFAVHSLKDLPTAAPKGLLLAAVPVREDPRDALVARDGLTFAG
LPEGARVGTGSPRRMAQLNAWARALGRRIETVPIRGNVDTRIGYVTSGELDAVVLAAAGL
SRLGRLDVVTEYLATDEVLPAPGQGALAVECAAGDAGLAALLGELDDPVTRAAVTAERSL
LAALEAGCSAPVGALAEPGVPGDGDDESVTELRLRGVVGTTDGSELVQMSATGTLSASLD
EAAALGRWLAEDMLAKGASGLMGERAR
>F8YMT2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O104:H4 str. LB226692|TrEMBL
MVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLG
LVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGT
RLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRE
LLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRG
ERRGAPQNAEQMGISLAEELLNNGAREILAEVYNGDAPA
>A3UXP9|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio splendidus 12B01|TrEMBL
MTNSAPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPKGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAAVGTCSLRRQCQLLEYRPDLIIKELRGNVGTRLGKLDDGQYDAIVLAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYSLLDGDNIWLRALVGEPDGSKMVRGEISGLRKDAEALGVTLANQLLDDGA
REILTKLYADQE
>H3RZ65|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1114|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H6L499|hydroxymethylbilane synthase|EC 2.5.1.61|Saprospira grandis (strain Lewin)|TrEMBL
MRKLIIGTRGSKLALWQAYYTQEQLKALGFESELKIIKTQGDRIQHLSFDKMEGKGFFTK
EIEAALLEGEIDLAVHSMKDMPTTQPKGLKLSAVSYRDKVADLLLIRKEVLAEKEPLGLP
PNAIVGTSSARRKAQILDFRPDLEIKDIRGNVPTRLNKLREGQFDAILLAAAGVNRLEIP
LDEFEVFEFDPREFVPAPAQGVLVWQCRSEDLQTQRIVAKLHKKEVVACTNVERRLLQLF
DGGCQMPLGAYCYRENGSYHAYAAVAESWNSPVKRVQLSASTHTKLAERLYALLQEEA
>F8ZZQ0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HCUF01|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>E7ZSM5|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 414877|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>F7NJ62|hydroxymethylbilane synthase|EC 2.5.1.61|Acetonema longum DSM 6540|TrEMBL
MEKQRLIIGTRASKLALWQAHYIAGRLEERYPDSQIEIRHITTTGDKILDVPLAKIGGKG
LFTKEIESAMLSGEIDLAVHSLKDMPTELPAGLTLAAVTERLDPGDAFVSNRYQSLDELP
QGAKVGTSSLRRRAQLLACRPDLVISDLRGNVDTRLRKLEDEKLDAIVLAVAGLKRLDLG
DRIRQVLPRSICLPAVGQGALAIETRADDRHTVDMISCLEDAPTRLAVTAERSFLRMVEG
GCQVPVGVYADWQEDILRLTAVILSLDGQRIVRDWLWGMQPDQAVAEEMGRELADKMLAA
GGRTILSELDCREGGEH
>B9QSU5|hydroxymethylbilane synthase|EC 2.5.1.61|Labrenzia alexandrii DFL-11|TrEMBL
MQSNPLRIGTRGSALALAQAHETRARLMAAHDLPEDAFEIVVIKTSGDQIQDRPLSEVGG
KGLFTKEIEEAMLDGRIDLAVHSSKDMPTVLPDGLALTAFLPREDVRDAFLSPKAKTLMD
LPHGAVVGSSSLRRQAMIKRLRPDIEVVMYRGNLQTRLRKLAEGEVDATLLAYAGLRRLG
LEEEVTSLLETEDFLPAVGQGAICIESREGDERTLEMLQAIHDRETQIRLDAERAFLAVL
DGSCRTPIGGLALLNGDELTLKGTVLKPDGSEVHDEVRSGGAVDAVQIGQAAGEALKAKM
GPGFLSSH
>H8DFB1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli SCI-07|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A6D6U6|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio shilonii AK1|TrEMBL
MLGLWHDQKQRNAYENDMTQTQPIRIATRKSPLALWQAHYVKDALIAAHPGLEVELVTMV
TKGDIILDTPLAKVGGKGLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICERE
DPRDAFVSNTYTNISELPQGAVVGTCSLRRQCQLKEQRPDLVIKELRGNVGTRLGKLDNG
EYDAIILAAAGLKRLELESRIRSFIEPEESLPAVGQGAVGIECRLDDERLIKLLEPLNHT
NTADRVLCERAMNLTLEGGCQVPIGSYSLIDGDEIWLRALVGEPDGSKIVRGEIRGKRAD
AEALGVQLANQLLNDGAKEILEKLYQEHE
>E8AMP0|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 446600|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>B0GKN2|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis biovar Antiqua str. UG05-0454|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>Q83H95|hydroxymethylbilane synthase|EC 2.5.1.61|Tropheryma whipplei (strain TW08/27)|TrEMBL
MYPLRIGTRSSLLATAQTAQVQKTMRDVFLLDTQQVLIQTGSVRRRDGSFVAALRTALLE
GECDLAVHSLKDIPIAPHEGTLITAVLPREDPCDVLCARKDLTLTTLPSGAKVGTASARR
RAQILNFRPDLDVVSLRGNIDKRLIHLDTLDAIVLSAAGLKRIDREDAITESFDIHDWPT
AAGQGSLAIEVCRAQLDDPQNRVAVTYRLDNPMARVTTTAERGVLSLLQADCFSPIAVHA
VYTANDKSLRLHAKVFSRDGKIFCESIRFARLVKQLTDTNQNHTKNSGSDDIGNALEVAM
TLAKTVVDELLSKNAREILKQ
>H2JSJ7|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces hygroscopicus subsp. jinggangensis (strain 5008)|TrEMBL
MPVPELIRIVSRDSPMALAQVERVRAELAVLHPGVRTAVVPVKTTGDKWLGDLSQVEGKG
AFTKEVDAALLAGEADLAVHCVKDVPADRPLPAGTVFAAFLKRDDIRDALVHPDGLTLDE
LPAGTRIGTSAVRRIAQLAATHPHLECVPFRGNANRRLEKLAAGEADALLLAVSGLERIG
RTDVISEVLSPETMMPPIGAGILALQCREDDSELIDAVSGLSDPATHREATAERMFLHVL
QGHCNSPIAGYARVDRSGELSLRACVFTPDGKTRLNAHEWAGRLDPATLGTSVAVALLRQ
GAREIIDGIPH
>E5TSZ6|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CGS03|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>D4E031|hydroxymethylbilane synthase|EC 2.5.1.61|Serratia odorifera DSM 4582|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQQRLMASHPDLQVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPVEFPAGLGLVTICERDDPRDAFVSNRFASLDQLP
QGSVVGTSSLRRQCQLRQRRPDLLVRDLRGNVGTRLAKLDNGDYDAIILAVAGLKRLGLE
QRIRSPMSPEESLPAVGQGAVGIECRLDDAVTRALLAPLNHELTATRVRAERAMNTRLEG
GCQVPIGSYAELDGDTLWLRALVGAPDGSLMVRGERRGPAAQAEHMGIELAEELLAKGAR
DILRDVYQGNPPA
>D4GYS3|hydroxymethylbilane synthase|EC 2.5.1.61|Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)|TrEMBL
MTTTLRLATRGSALARAQAASVQGALAGRRLDVELVEVETTGDRIQDELIHRLGKTGAFV
RALDERVLDGEVDAAVHSMKDMPTEKPADLVVAGVPERAPAGDVLVTAEGHDIDDLPEGA
VVGTSSLRRQAQLLNYRDDLEVEPLRGNVDTRIEKLLATHLQREHEARVENDKERQGKKG
KTDHDEAFDETADEWFEGLTELERQALGRQVETEYDAIVLAEAGLKRSGLTEKVNYERLP
RTTFVPAPGQGAIAVTAADSVVIELIRDKLDHPRTRVETTVERTILAELGGGCIAPVGVH
ALLQGEHVHVDVQVLATDGSESIKTSRDLPVGNHANAAREFAAALCDRGAGQLVDAAREE
AEE
>C0YYX1|hydroxymethylbilane synthase|EC 2.5.1.61|Lactobacillus reuteri MM2-3|TrEMBL
MTNKVIVGSRKSKLAMAQTELVIASLEKIFPDIKFEIKNVITEGDRNRHVSLAKIGGKGV
FVKEIEDELKDGTIDFAVHSLKDVMPILPEELVLGAFPKRVSPYDCLVSRKNLSSLNDLP
KGARIGTNSLRRQGQLLSIRPDLKIIPIRGNIDTRLRKIDTEALDGIILAEAGLTRLNID
LSSYHVLDLQNYIMPAVGQGCLAIECRKNDTRIRKMLDQINDEESAYCVQVEREFMRELG
GSCNFPIGGHAYAKNGQILFDGLIASPNGEHVIKETKIPANNSGVGKKVADQLLAKDKFG
IIEGE
>I4ZWE1|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter sp. HA|TrEMBL
MKTLKIATRQSPLALWQAEHIRARLQELHADLQVELVTFVTQGDKILDTPLAKIGGKGLF
VKELEAALLDGRADLAVHSMKDVPMALPEGLSLAVICEREDPLDAFVSNTYASFDELPQG
AKVGTSSLRRKSQILKARPDLEIIDLRGNVGTRLSKLDAGNYDAIILASAGLKRLGLADR
IRHTLKPAVSLPAVGQGALGLECRDRDQAVLDLILPLLHAETDACVRAERAFNAYLEGGC
QVPIAGYATLQDGKIAIEGRVGSVDGATLLKAELQGDVNQAEQLGVALAQNLLAQGAGDL
LKALYS
>D4JKD1|hydroxymethylbilane synthase|EC 2.5.1.61|Eubacterium rectale M104/1|TrEMBL
MKYLIGTRGSKLALVQTDYVIDKLKRAYPDDDFKAVIIKTTGDLEQKKALDKIGSKGIFV
KEIEDELLSGKIHMAVHSMKDMPDEPAAGLTFAKAWKREDPRDVLVLKNAASLDELPHGA
VIGTGSKRRKYQLLKLRPDLKVVGIRGNIDTRLRKLYDGEIIYEEIADNTVNNNEIANEK
QNKYNEYRLDGIVLAAAGIKRIGRDSEITQYFSEDDMIPAPAQGTLALELRADNAELMAK
LDALSDEKTNLCAGIEREFLKRIGGNCHLPVAAYCDIVSEKDCGNDSDKNNRLKLLAMFG
SEDGKKLARTEQVWDMTSDRNNIVERAVHDIRYKLEID
>F6FZA8|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia solanacearum (strain Po82)|TrEMBL
MSSNARPTSVESPLAAQAPTRLVIASRESRLAMWQAEYVRAALQKYYPACDVSILGMTTR
GDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMELPPGFALPAILEREDP
RDAFVSNQYADLAALPAGAVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLAKLDRGDY
AAIILAAAGLKRLGLSERIRAVIASDVSLPAAGQGALGIETRADRTDVQAWLAPLHHLPT
ALAVTAERAVSRRLGGSCQVPLAAFAHWTDAGALRLRAFVASQDGRRKLAAEGEATPTTL
AEADALGARVAQQMLDGGARDILATLGADAPPAT
>I0KT39|hydroxymethylbilane synthase|EC 2.5.1.61|Stenotrophomonas maltophilia D457|TrEMBL
METVRIATRKSPLALWQSEHVANRLRQAHPGLHVELVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDEPFALPAMLTRHDPADGFVSNLYASLDALPIG
ARVGTSSLRRQAQLRALRPDLELLDLRGNVNTRLAKLDNGGYDAIVLAVAGLERLGLGGR
IVARLQPPQWLPAPAQGAVAVECDGGNTRLMALFATLDDAATRACVEAERAMNRALHGSC
HVPVAAIAQWQGDDLHLQGLVGSASDGRAVRAEAVGPARDPEALGQRVAKMLLEAGAGEL
LNV
>D3F2Z8|hydroxymethylbilane synthase|EC 2.5.1.61|Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577)|TrEMBL
MSVLRIGTRASALALVQAEHVASLLRDGGAQVEVIPITTSGDRGRLLGDKSRWVKELEAA
LLADEVDVAVHSAKDVPAELPDGFVLAGVPARADARDALCGAASLEQLPDGAVVGTSSLR
RAAELRALRPDLGVVALRGNVDTRLRKLADGQAAAIVLAVAGLERLDRGAAIGAVLDQLV
PAPGQGALALETRADDDRARAAAAAITDADAAACLAAERALVRRLGATCHTPLGAHAVRT
ADGGLRLRSFVGLPDGSAWLRDELSAAAGIDPETFGVAAGTRLLAAGAAELLARAEQAGA
GSPPPASTPEGVPL
>F0Q7J2|hydroxymethylbilane synthase|EC 2.5.1.61|Acidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)|TrEMBL
MHPTSPSTTSAASVLPPIVIATRESRLALWQAEHVQALLRARGHAVELLGMTTKGDQILD
RTLSKVGGKGLFVKELEVALEEGRAHVAVHSLKDVPMELPEGFELACVMEREDPRDAFVS
PRHACLADLPQGAVVGTSSLRRQVLLQALRPDLDIQPLRGNLDTRLRKLDEGQYDAIVLA
AAGLKRLGMEDRIRALFEPDEMLPAAGQGALGLEVRSERHDLLQAVAPLAHQATWLCVAA
ERAVSRALGGSCSVPLAAHGRWTDAGTLRLDGAWGDPEGIRPLVRVQVSAPVASLPEAEA
LGSAVAARLRADGAQIPA
>D5V9D9|hydroxymethylbilane synthase|EC 2.5.1.61|Moraxella catarrhalis (strain RH4)|TrEMBL
MTIRTLTIATRQSPLALWQANFIKAKLEQLYPSLSVELLEMVTKGDKILDTPLAKIGGKG
LFVKELEQALYDKRADIAVHSLKDVPMVLPEGLMLGAYCERHAPTDAFVSNRFEHLDDLP
TGAVLGTSSLRRECQLRQARPDLDIKSLRGNVGTRLGKLDAGEYDAIILATSGLERLGLH
ERIRHELDDELSLPAVGQGALAIECRSDDEAIKLLLSPLNHPKTRLCVLAERAMNRALEG
GCQVPIAGFAVIEDGMLTLRGRVGSVDGKTLLKAQQSRKLMGEIQLDEQAAEQLGIDVAH
ELLMQGADDILKQVYQNALNS
>B6JII8|hydroxymethylbilane synthase|EC 2.5.1.61|Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)|TrEMBL
MAQKTGDGVTDKAMRIGTRKSVMALAQTSEIARQLTAADPALDVEIVKFETTGDQDQTGK
LLDLGGKGGAFVAQIRDAVREGRLEAAMHSLKDMPGNEDTPGLVIGATLTRDPPTDALVV
RHGVTLADLRRTGGKGFKIGTNAVRRAAYVRRLFPECEIIHFRGAADTRIRKLDNGEKQR
LPEGGEVGPADALVMAQAGLERVGCADRIAHCFSPDEILPAVGQGIVAVECAASDWCTLA
RLAQIDDPVSRCCAAAEREVLWVLNGHCNSPIAGYAIVEGDDVLLKAAVLDEANDHFIEV
TRRGPASRPRELGRAVAFELLAKGAADVIARTRPVSAH
>G9VTJ6|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 507440-20|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>F0P3N4|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus pseudintermedius (strain ED99)|TrEMBL
MRKLIVGSRRSQLALTQSQQFIDRLKEVDPTLDIEIKEIVTKGDQIVDRQLSKVGGKGLF
VKEIQNELFSRDIDMAIHSLKDVPSELPEGLTLGCIPDRENPFDAFISKNHIPLDELPDG
SIIGTSSLRRGAQILAKYPNLEIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDD
IVTTYLDEDLLVPAIGQGALGIECRADDDELLALLAKVHNEDVSACVTAERTFLKEMNGS
CQVPIGGYATRKNDTEIQFTGLIMSPDGKQRFEYTFSGQDPIQVGSEVSRVLKSQGADKI
IQALNEKEV
>D7WB53|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium genitalium ATCC 33030|TrEMBL
MTETLRVATRGSKLATTQAGHIRDALISAGHSAELTIVTTAGDMSQAPVERIGVGVFTTA
IRQALFDGEADVAVHSFKDLPTAHEPRTHLIIPVREDRREALIARDGLKLADLPSGARVG
TSAPRRIAQLRAKRPDLDIHPLRGNIESRMGRVTSGELDAVVLAYAGMSRVGLGERATEV
FAPEDFMPAPAQGALAVECRAEDAQAVAAIDTLVDDFATRCALTERFVLATLEAGCTAPV
AASAVLDGDEITVRGGVFALDGSAQLVREASGTDPREVGQACAQQLFDAGAAQFL
>D7WB53|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium genitalium ATCC 33030|TrEMBL
MTETLRVATRGSKLATTQAGHIRDALISAGHSAELTIVTTAGDMSQAPVERIGVGVFTTA
IRQALFDGEADVAVHSFKDLPTAHEPRTHLIIPVREDRREALIARDGLKLADLPSGARVG
TSAPRRIAQLRAKRPDLDIHPLRGNIESRMGRVTSGELDAVVLAYAGMSRVGLGERATEV
FAPEDFMPAPAQGALAVECRAEDAQAVAAIDTLVDDFATRCALTERFVLATLEAGCTAPV
AASAVLDGDEITVRGGVFALDGSAQLVREASGTDPREVGQACAQQLFDAGAAQFL
>D4J1N8|hydroxymethylbilane synthase|EC 2.5.1.61|Butyrivibrio fibrisolvens|TrEMBL
MLIKVGTRGSKLALVQTNYVIEQLKKAFPENEYEVVVIKTTGDIDQSRPLDQIGSKGLFV
DEIERALVADEIQLAVHSMKDMPSKPAKGCVFAKSWTREDARDVIIFREVDSIEELPKNA
KIATGSKRRSYQLLSLRPDLELCPIRGNIDTRLRKLVEGNSDGTILDGIVLAAAGLNRLK
ISLDHYQILEVDEMIPSPAQGTLAIELNEKIKSFLIWSIHYQMKRQIISHIWREVFLKG
>F0QLT4|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii (strain TCDC-AB0715)|TrEMBL
MLEFMKTLKIATRQSPLALWQAEHIRARLQELHPDLTVELVKFVTQGDKILDTPLAKIGG
KGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQFEKFAD
LPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAGLKRLG
LAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLTLIQPLLHPETDVCVRAERAFNAYL
EGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARNLLDQG
AGDLLKALY
>C7R6S3|hydroxymethylbilane synthase|EC 2.5.1.61|Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125)|TrEMBL
MSISTLRIATRQSPLAMWQAEYVQSRLQQLHPDLTVELVPMTTQGDKILGTPLTKIGGKG
LFVKELEQAMLEGRADIAVHSMKDVPYQFPEGLELKVICEREDPTDAFVSNKYHNLDDLP
CGANVGTSSLRRKIQLLRARPDLKITDLRGNVGTRLSKLDDGNYDAIVLASAGLKRLGLE
ERIRSQFEPELMLPAPGQGAVGIEARTNDPDLDAILQPLQDETTSLRVLAERTITKTLQA
SCQVPVAAFATINDDTLSLRALVGGVDQQIIEASAEGPAQDALAIGHKVSQELLELGARE
LIQELAATVDH
>B2TUW0|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMTSHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>Q4JAM6|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)|TrEMBL
MRIRIAARGSLLSRIQVKMVEDKLRNLGIETELIVVKTKADLFQDKPLNSLGKGVFEKEV
NEAVINGEADIAVHSMKDMLSDMDEKLVLYGVLPRDSPYDSLVAEKDLFNIESGKVIGTS
SIRRRSMISFYRRDLVVKDLRGNIDTRLKKYQSKEYDGIVIAEAAIKRLNSVVRYYKIDP
KIITPEANQGIIAIVGRVNEKLKTLFRELNDERTLKEALVERTVVKLLGGGCHSPIGILA
SMISENEFNVISTYVISDKKKITIEGIYRGDPTTVGEKVVKDMVKVLKHENSSVTT
>A6A4G5|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae MZO-2|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGALGIECRVDDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDHIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>F7WMG5|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis (strain CCDC5079)|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>G8NIR2|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella suis VBI22|TrEMBL
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>E0TD20|hydroxymethylbilane synthase|EC 2.5.1.61|Parvularcula bermudensis (strain ATCC BAA-594 / HTCC2503 / KCTC 12087)|TrEMBL
MSFKPLRIASRRSPLAVAQALWVRDRLAEALGIDEVDRDAAFPHETFVTTGDRMLNPTLA
DIGGKGLFTKEIEIALLDGQADIAVHSMKDMPAQMPPGLVLAAVPVREDPRDAFVTLDGR
PLDQMPAGARIGTSSTRRRAQLARLRPDLALVPMRGNVGTRLQKLAAGEAEGTFLAEAGL
RRLGMTDVKREALSPARMLPALGQGALCVQARSGDHETLSACAHINNRPTALAAAAERAL
ISGLDGSCKTPIGGLARQTGDSLILEGQILTPDGRRVLRGERTVAIGGMTWEAVLDSARA
AGADLAAYMRAEAGADLAAMLGDQ
>F9ABR1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HE-09|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDAILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDNIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>H7V8Z9|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli LMG 23336|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>H8EWH1|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)|TrEMBL
MLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALREAMEAGLVDA
AVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTSSPRRAAQLR
ALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLEPVQMLPAPA
QGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGAIAEVVESID
EDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGARELMWGVRH
>G8AEB0|hydroxymethylbilane synthase|EC 2.5.1.61|Azospirillum brasilense Sp245|TrEMBL
MTQPLRIGTRGSPLALAQAHETRDRLIAAHPHLAAPGAIEIVVFKTTGDRILDRTLAEAG
GKGLFTKELEDALLDGRADLAVHSMKDVPTWMPDGLEISTLLPREDTRDAFFSRGGHTVD
TLPAGSVVGTAGLRRQAQILERRPDLTVVPFRGNVQSRLAKLEAGEVDATLLALAGLRRL
GLTDRITAVLEHEEMLPAVAQGAIGIEIRSADDSTRALLAPLNCAATTARVTAERALLAM
LDGSCRTPIAGLATLDGDRLHLKAKVLSNDGRQVFRAERSGSASDAAAIGADAGAEIKAV
LPPDFFKS
>F0EYP1|hydroxymethylbilane synthase|EC 2.5.1.61|Kingella denitrificans ATCC 33394|TrEMBL
MNIPQKLTIASRESALAMWQAEHIQAKLQALYPSCTVDILGMTTQGDQILDKTLSKIGGK
GLFIKELETALQENRADLAVHSLKDVPMDLPEGFVLVAVGERANPFDALVSNRFERLEEL
PEGAVVGTSSLRREAQLRARFPHLQVKPLRGNVQTRLAKLDNGDYDAIILAAAGLERLQL
HGRIRNLLPPSDSLPAAGQGALGIEIAAHRTDLVDILLPLNHAQTAACVTAERALARALG
GSCQVPLGAYCTADEYGLLTLHGLVAHPDGSVVMTANAQAPAPYADALGRAVAKKLSDDG
AREVIAAVLSETH
>G7C032|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-61A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>F3IWJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. aptata str. DSM 50252|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLIVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDQLP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGSVLLHADARAPQTSAQALGVQVAEALLEQGAA
DILKAVYGEANNE
>H3WTZ7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU129|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSIIPDGLTLGCIPDREIPFDAYIAKNHIPLEELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDVLLPAIGQGALGIECRSDDKELLDLLAKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIVHDNQIEFTGLIMSPDGKERYEHTTLGSDPVQLGIEVSQVLKKQGAYDI
IKKLNEAE
>D0ZYP5|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydophila pneumoniae (strain LPCoLN)|TrEMBL
MLSVCYSDPFLSDFCQGKRPLRIASRNSNLAKAQVHECISLLRSWYPKLWFQLSTTETTG
DRDKKIPLHLVENSYFFTDGVDALVHKGVCDLAIHSAKDLPETPSLPVVAITRCLHPADL
LVYADHYVHEPLPLRPRLGSSSLRRSAVLKQLFPQGQILDIRGTIEERLDQLHRGHYDAI
VLAKAASLRLHLHHAYSIELPPPYHALQGSLAITAKDHAGKWKQLFTPIHCHSS
>F8DU68|hydroxymethylbilane synthase|EC 2.5.1.61|Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1)|TrEMBL
MQLPFRLGSRGSPLALIQARSVASALCAAHSWSEDAVVIVPIRTSGDKNRHQALADIGGK
ALWTKELDIALTTGQIDAAVHSMKDVETFRPSHISIAAMLPREDVHDRLIGIPSLEVLPY
SGCVGTASPRRAAQIRCIRPDIEIKLLRGNIDTRLEKLANKQFDATLLAAAGLIRLGRND
VGYDVPLDQMLPAAGQGAIGIEALADSAAWEKVSIIDHYPTHLAVQSERQLLLRLNADCH
SPIAVFAEILEKNIRLRACLYTENGKFSASIDKEISQPSDAFEVGSLLLNQSPPEVQALF
LPRVLSER
>I1XF51|hydroxymethylbilane synthase|EC 2.5.1.61|Methylophaga sp. (strain JAM1)|TrEMBL
MSQRTVRIATRRSPLAIWQAEFVRDSLLALDPHLNIELVRIKTQGDIILDTPLAKVGGKG
LFVKELEQSMLAGEADIAVHSMKDVPVEFPEGLHLPVICERHDPHDAFVSNHFENVDDLP
EGAVVGTSSLRRECQLRHYRPDLKIVPLRGNVNTRLAKLDAGNFDAIILAKAGLERLGFD
QRIRSALTPEQSLPAIGQGALGIETRINDDEMNALIALLNCELTSITVKAERALNRRLKG
GCQVPIGGYAILNGDDLWVRGLVGRPDGTEMLQQEIRGKASESEQLGLTLGEMLLNQGAD
KILADVYDA
>G2Z9Q4|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria ivanovii (strain ATCC BAA-678 / PAM 55)|TrEMBL
MKRKIIVGSRRSKLALTQSGWVIARLKANYPSIDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDGLIDFAVHSMKDIPSSLKKGLTIGAIPKRESALDCFVFNTVATFKDLPK
GAVIGTSSLRRAAQILRHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPELCLPAVGQGALAIECRESDQQICDMLASIHHEETGVCVEAERVFLKKL
NGGCEVPIAGFATKTDGIVHFKGLVGNSDGTTILSAEQSGENPATIGNQVAESLLSEGAA
SIINELRNS
>F8C344|hydroxymethylbilane synthase|EC 2.5.1.61|Thermodesulfobacterium sp. (strain OPB45)|TrEMBL
MVIKVGTRGSKLALAQTDWVISQLKSFFPKINFEKIIIKTTGDKILDSPLSKIGGKGLFV
KEIEEALLRGEIDFAIHSMKDVPSLIPEGLEIACIPQRESPFDVWISNYKDILELPSYSK
IGTSSLRRLSQLKKLRKDLEILPLRGNVDTRLRKWKEGQFDGIILAEAGLKRLGIEISYK
RLTIEEMVPAVGQGALGIEIRKDDKKLKEMLSKIHSETTAICIKVERTFLKTLEGGCQVP
IGAYCWIENSKLFVIGFISDLEGERFYKLRDEGSISEAEKLGERLAKKLLKAGGEEILKE
IYKRE
>G8VG95|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes TypeIA2 P.acn17|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>G8VG95|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes TypeIA2 P.acn17|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>I5G1C6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA3|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D6XSZ7|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10)|TrEMBL
MTRTITLGSRRSNLAMTQTRWVISELEKLGLPFQFEIKEITTRGDEILDVTLSKVGGKGL
FVKEIEQAMHNGEIDMAVHSMKDVPSTRSEGLVLASVPKRYDPRDALISNSGKTLMELPA
GSIVGTSSLRRGSQVLAKRPDLEIQWIRGNIDTRLRKCREENFDAIILAAAGLERVGWTE
DIVTEFLDPDLCLPAVGQGALGLECREDDYELRELLAHINHEQTAITVAAERAFLRTVEG
GCQVPIGAYATLDEQNQIHLTALVASTDGKQVFKESIIGEDPEYIGTEVAERILRQGAKG
VLDQVKEDLENS
>I5ZBJ7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC1863|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>D0GL80|hydroxymethylbilane synthase|EC 2.5.1.61|Leptotrichia goodfellowii F0264|TrEMBL
MKSNKIIIGTRGSILALAQAEKVKEMLIAKYDELRKKEDFKGISDFNKNESLTIELKIIV
TTGDKDLRDFDKIKGTTQKELFVKEIEKEMLENKIDFAVHSLKDMPQQTPEGLLNACFPL
REDNRDVIVSKSGKKLNELREKSVIGTGSIRRETELLNLRKDIIIKPIRGNIHTRLKKLD
NGEYDAIILAAAGLKRTGLSDRITEYFEDEVFMPAPGQGILCIQCRENDDRIRELLEIIN
DKEVGIMCETEREFSRIFDGGCHTPIGCSSTIEGNTLKLKGVYNKDGKRIFSEIEGDKNN
PKEIAQKLAKEIKNNE
>Q0TAS2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O6:K15:H31 (strain 536 / UPEC)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F0MUN2|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup B (strain M01-240355)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVILQADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>E3JIN6|hydroxymethylbilane synthase|EC 2.5.1.61|Buchnera aphidicola subsp. Acyrthosiphon pisum (strain JF99)|TrEMBL
MYNKTLRIATRKSPLALKQTKYVQKKILSLYPDLNIKLVPIVTHGDNILNKSLSKIGGKG
LFIKELELALLENKADIAIHSMKDLPVKITKELCLVSICKRGNALDSLVSNNYQSINQLP
KGAIVGTSSLRRQCQLITYRPDLIISPLRGNIETRIAKLDQGKYDAIILATEGLNRLRLK
NRITQIIPAELSLPSCGQGAIGIQSRLHDKKVLFFLSRLNHINTFIEINAERAFCRKLES
GCQIPIGSYAILKKNKIWLRGLVGSPNGKIILKGERIGCYNTGEKMGYSLADELLKNGAK
NILNNLHIKQSYCI
>F9U3V9|hydroxymethylbilane synthase|EC 2.5.1.61|Marichromatium purpuratum 984|TrEMBL
MSNCIRIATRKSPLAMWQAEHTAALLKSLHPGLEVEIVGMTTKGDQLLDSPLSKVGGKGL
FVKELEQGMLEGTADIAVHSMKDVPVEFPEGLHLAVIMERENPYDAFVSNNYEGLADLPE
GAVVGTSSLRRECQLADRRPDLQIEPLRGNVNTRLAKLDGGQYDAIILAAAGLIRLGFES
RIRSCIDPVDSLPAIGQGAIGIECRIDDQRVHDLIAPLAHRDTTDRVLAERAMNARLNGG
CQVPIGGHAVLDGDQLTIKGLVGTTDGKRILRAEATGPRAEAEAIGLRVAEDLLGQGAGE
ILAALHESH
>A0QR18|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)|TrEMBL
MANNRDSVIRLGTRGSLLATTQAGTVRDALLAAGHPCELVIISTEGDRNQGPIADIGIGV
FTAALREAIHDGRVDMAVHSYKDLPTASDERFCIPAIPRREDPRDALVARDGLVLGELPT
GSVIGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVTSGELDGIVVARAGLARIGRLN
VVTETLEPVQMLPAPAQGALAVECRAGDTELIAILSELDDADTRAAVTAERVLLAELEAG
CSAPVGAIAEVVESIDEDGNVFEELSLRGCAATLDGSDVIRASGIGTPDRAAELGVSVAA
ELFDLGARELLEERGSEK
>Q5FPS5|hydroxymethylbilane synthase|EC 2.5.1.61|Gluconobacter oxydans (strain 621H)|TrEMBL
MNGLKLPFMNAPVLPSEALQRVAAEAVRRSHAAEPPTGRKLPLRVGSRASPLALVQTRNF
LTRLTRFCPVLRDMGAFQEYQISTEGDRNLVQRLAEIGGKGLFAKEIHEALAAGRIDFAV
HSLKDLETNLPPGLVLACTLKREDARDALILRDRDVKVDPQRPYDCLPEGALIGCASVRR
QAQMLHVRPDLRFCLLRGNVQTRLDKLRAGACEATLLALAGLRRLGMEDRVDVVLEPDQM
LPASGQGIVGVTVRESDLELRELLSAIEDPEARAVSTAERALLAELDGSCRTPIGGYARI
ENGVLKLSGMIASEDGTFLLRREIEGAPLEAARLGTELADELRRDTPAHIFDEMRRP
>I4JQN7|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas stutzeri TS44|TrEMBL
MSREIRIATRKSALALWQAEYVKARLEASHPGLTVSLVPMVSRGDKLLDAPLAKIGGKGL
FVKELETALLENEADIAVHSMKDVPMEFPAGLGLYCICEREDPRDAFASNTYDSLDALPA
GSVVGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFGE
RIRSSIGVDESLPAGGQGAVGIECRSADSEVHQLLACLNDPATATRVSAERALNKRLNGG
CQVPIACYAVLEGEQLWLRGLVGQPDGSLLLRAEGRAPAAEAEALGVRVAEDLLAQGAER
ILQAVYGEAGDA
>I4JQN7|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas stutzeri TS44|TrEMBL
MSREIRIATRKSALALWQAEYVKARLEASHPGLTVSLVPMVSRGDKLLDAPLAKIGGKGL
FVKELETALLENEADIAVHSMKDVPMEFPAGLGLYCICEREDPRDAFASNTYDSLDALPA
GSVVGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFGE
RIRSSIGVDESLPAGGQGAVGIECRSADSEVHQLLACLNDPATATRVSAERALNKRLNGG
CQVPIACYAVLEGEQLWLRGLVGQPDGSLLLRAEGRAPAAEAEALGVRVAEDLLAQGAER
ILQAVYGEAGDA
>E4MNS0|hydroxymethylbilane synthase|EC 2.5.1.61|Capnocytophaga ochracea F0287|TrEMBL
MNTIRIGTRDSELALWQAKTVQNQLKTLGYATEIVSTKSHGDIELSKPLYEMGVTGIFTK
ALDIALLNSEIDIAVHSMKDVPTALPEGIVVGAVLKRGNPHDVLVYKGDLSFLEAEIVTI
ATSSLRRKAQWLHRYPHHNIESLRGNVNTRLQKLTDNPWNGAIFAAAGLERINKLPEKHL
VLDWMLPAPAQGAIVVVVREANVALQKKLLPLHDDYTYIATQLERDFLRALEGGCTAPIG
AFAEFKDDKLYFKGGLWSEDGKESSVIDEVLTQIDEYTGEKLATMVRS
>E7I8E3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli LT-68|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQNAEQMGISLAEELLNNGAREILAEVYNGDAPA
>B6BRQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Candidatus Pelagibacter sp. HTCC7211|TrEMBL
MNKKITIGSRGSKLALIYAQKAKDKIIQNTNIKDEDIIIKEITTKGDQVQDMRLSEVGGK
GLFSTNIEKELQDKKIDIAVHALKDMPAIETVGLRTNTFLKRNDPREILIAQSGKKLNEL
KINSIIGTSSYRREFQIKKIRSDINCKLIRGNVDTRIKKLNDGLYDAIILSYAGIKSLEI
EDKITEIFSIEEIIPSAGQGIIALQCRNNDIEIISVLDEINDKETSSMAHAERNVLKVLE
GDCETAIGTHAIIEEDKIILQAELFSLDGKQRFFEKKSSKINDARELGKELGEILKTKSN
NSYKR
>D9RHV7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain JKD6159)|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTLNGTNPVELGKKVSNKLKKQGAYEI
IKRLNEQH
>C6AQ25|hydroxymethylbilane synthase|EC 2.5.1.61|Aggregatibacter aphrophilus (strain NJ8700)|TrEMBL
MLEKTLKIATRQSPLALWQANYVKDCLQQLYPDLIVELVPMVTKGDVILDSPLAKIGGKG
LFVKELENALLNKEADIAVHSMKDVPMQFPEGLGLAVICKREDPRDAFVSNSYRTFDELP
QSAVVGTSSLRRQCQLKALRPDLDIRSLRGNVGTRLSKLDNGDYDAIILASAGLIRLGLA
DRIASFIEVEQSLPAAGQGAVGIECRTDDVQVKQLLAPLADAETTCCVLAERAMNNHLQG
GCQVPIGGYAVLQQGQLYLRALVGNVDGSQIIRAEGKSAVKNADVLGVQIAEQLLAQGAD
KILQSIYS
>E8P9D6|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii (strain 1656-2)|TrEMBL
MLEFMKTLKIATRQSPLALWQAEHIRARLQELHPDLTVELVKFVTQGDKILDTPLAKIGG
KGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQFEKFAD
LPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAGLKRLG
LAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLTLIQPLLHPETDVCVRAERAFNAYL
EGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARNLLDQG
AGDLLKALY
>A3YRH7|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 260.94|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLECLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>I1DHF0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio tubiashii NCIMB 1337 = ATCC 19106|TrEMBL
MTQQTPIRIATRKSPLALWQAHYVKDALMAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQIKESRPDLVIKELRGNLGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIKSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHKETADRVLCERAMNLTLE
GGCQVPIGSYSLIDGDNIWLRALVGEPDGSKIVRGEIRGSRTDAEALGIELANQLLDQGA
KEILTKLYAEHE
>I1DHF0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio tubiashii NCIMB 1337 = ATCC 19106|TrEMBL
MTQQTPIRIATRKSPLALWQAHYVKDALMAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQIKESRPDLVIKELRGNLGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIKSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHKETADRVLCERAMNLTLE
GGCQVPIGSYSLIDGDNIWLRALVGEPDGSKIVRGEIRGSRTDAEALGIELANQLLDQGA
KEILTKLYAEHE
>C7N5L0|hydroxymethylbilane synthase|EC 2.5.1.61|Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1)|TrEMBL
MPERFVIGTRGSKLALWQTETVGRAIMRAFPEIEVEIRVRNTTGDINLASPLAEIGDKGL
FTRELETDLLLGEVDMCVHSLKDLETEQPEGCVVAGVLPRADARDVLVCGPRIQAASLAE
VPEGSRIGTGSRRRVAQLKANFPNMVPEGIRGNVDTRVAKAEGDDYEGAILAAAGMKRMG
YEDHIAAYLPIEDMIPAPGQGAIAMEVLKKNERAYQIARALNDPVTKACTDAERFVLFSL
EGGCSAPIGAHCRLEDGKYIFDACVLSLGGTKAARCHLEADADSADPMDMAWEVVSELIG
EGARAILRDIKNGKDTGQ
>H0JRT4|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus pyridinivorans AK37|TrEMBL
MSTEAASVSRDDVARQDRPLRIGTRGSVLATTQAGTVRDALIAAGRPAELVIITTKGDVT
PGPVQRIGVGVFTAELREALLAGEVDVAVHSYKDLPTFQDPRLVVAAVPEREDPRDALVA
RDGLVLGELPPGSKVGTSAPRRRAQLAALGLGLQIEPLRGNIDTRIGKVDSGELDAIVIA
RAGLSRIGRLDRVTESLEPVQMLPAPSQGALAVECRSDDPEMIELLAGLDHAPSRAAVVA
ERSLLAELEAGCTAPVGAIAEVVESLDDDGRVIEELSVRGCAAAMDGSDVLRASAVGAPE
KAEELGRRVARELLDLGARELMVEHGVLPETRPADD
>H0JRT4|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus pyridinivorans AK37|TrEMBL
MSTEAASVSRDDVARQDRPLRIGTRGSVLATTQAGTVRDALIAAGRPAELVIITTKGDVT
PGPVQRIGVGVFTAELREALLAGEVDVAVHSYKDLPTFQDPRLVVAAVPEREDPRDALVA
RDGLVLGELPPGSKVGTSAPRRRAQLAALGLGLQIEPLRGNIDTRIGKVDSGELDAIVIA
RAGLSRIGRLDRVTESLEPVQMLPAPSQGALAVECRSDDPEMIELLAGLDHAPSRAAVVA
ERSLLAELEAGCTAPVGAIAEVVESLDDDGRVIEELSVRGCAAAMDGSDVLRASAVGAPE
KAEELGRRVARELLDLGARELMVEHGVLPETRPADD
>I0PJT1|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium abscessus M93|TrEMBL
MIRIGTRGSLLATTQAGGIRDALRAKGHEAELVIVTTAGDQSAAPVEQIGVGVFTAALRE
AIADDVVDVAVHSYKDLPTAADPRFVIPAIPPREDYRDALVARDGLVLGELPAGSVIGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLSRVSNGDLDGVVVARAGLARIGRLDHITETLE
PVQVLPAPAQGALAVECRSEATDLVAVLAELDHADTRAAVTAERALLAELEAGCTAPVGA
IAEVVESIDEEGRVFDELSLRGCAAALDGSDVIRASGIGTPDRAAELGLAVARELLDLGA
RALIGR
>I0PJT1|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium abscessus M93|TrEMBL
MIRIGTRGSLLATTQAGGIRDALRAKGHEAELVIVTTAGDQSAAPVEQIGVGVFTAALRE
AIADDVVDVAVHSYKDLPTAADPRFVIPAIPPREDYRDALVARDGLVLGELPAGSVIGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLSRVSNGDLDGVVVARAGLARIGRLDHITETLE
PVQVLPAPAQGALAVECRSEATDLVAVLAELDHADTRAAVTAERALLAELEAGCTAPVGA
IAEVVESIDEEGRVFDELSLRGCAAALDGSDVIRASGIGTPDRAAELGLAVARELLDLGA
RALIGR
>H4EY24|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIGC128|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E7UW54|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Typhimurium str. TN061786|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>Q31UI3|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella boydii serotype 4 (strain Sb227)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>I6FUY7|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri 1235-66|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>E1PLQ5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni serotype HS21 (strain M1 / 99/308)|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPRGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>I0TYI9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-M|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>D8KA12|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrosococcus watsoni (strain C-113)|TrEMBL
MVFIMSAKTCLRIATRKSLLALWQAEYVANTLRHHYPDLSVELVRMSTQGDKILDTPLAK
IGGKGLFIKELEQGLFSGEADIAVHSMKDVPVDLPENLHIAVICQRGDPRDAFVSNHWQD
LDSLPEGARLGTSSLRRQSQVRERRPDFQVLDLRGNVNTRLAKLDNNEFDGIILATAGLK
RLELTHRIRESLAPEVSLPAIGQGAIGIECRKGDTATEELIKVLEHPPTRITLQAERALN
ARLAGGCQVPIAGYAELEDERLRLRALVGQPDGGRVIRGETWGMPGDAESLGASLGEDLL
RRGADKILAEVYSG
>Q5N4K4|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)|TrEMBL
MQTHWVQGELQRLYPDRQFDVQTMSTQGDIILDVALAKIGDKGLFTKELEVAMLAGEVDF
AVHSLKDLPTRLPEGLILGCVTEREDPADALVVHDRFKDHQLETLPEGTVIGTSSLRRLA
QLRHHYPHLQFKDVRGNLNTRLAKLDAGEYDALILAAAGLQRLSMADRIHQLIPAAVSLH
AVGQGALGIECRAEDPEILELLKALEHEPTSQRCLAERAFLRELEGGCQVPIGVNTAIAD
GTLTLTGMVASLDGQRLLRDQVSGPTSDPEALGLALAAQLKAQGAKEILDEIFATVRPEA
>B0TFU3|hydroxymethylbilane synthase|EC 2.5.1.61|Heliobacterium modesticaldum (strain ATCC 51547 / Ice1)|TrEMBL
MSALQRPVVIGTRDSALALWQTHWVLERLKELYPEQAFEVKHIKTKGDKILDVALAKIGD
KGLFTKELEVAMLNGEIDMAVHSMKDLPTLLPEGCAIGAICVREDCRDILISRNGGGLEE
LPRGAKVGTASLRRKAQIWKVRPDLELVDIRGNLQTRMRKMEEQNLDGLILAAAGVKRLG
WAEKITEYIPVDMCLPAVGQGSVGIEIREGDEAIGRLVAALNHAESALCVRAERALLRTL
EGGCQVPIGSLGRLSGGKLIVDGVVASLDGRTICRDRVEGDPADPEEAGVRLAKKLLQQG
AREILIQVRQETDLR
>G2MD90|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori SNT49|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLQRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCRLEREFIKGLNGGCQ
IPIGVHASLVGDRVKIQAVLGLPNGKEVITKEKQGDKTKAFDLVQELLEAFLQSGAKEIL
EKAQLF
>D4XLS6|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter haemolyticus ATCC 19194|TrEMBL
MKTLKIATRQSPLALWQAEHIRSRLNALYPDLTVELVKFVTQGDKILDTPLAKIGGKGLF
VKELEAALLDGRADLAVHSMKDVPMHLPDGLTLAVICEREDPLDAFVSNQYARFEDLPQG
AKVGTSSLRRKCQILQQRPDLEIVDLRGNVGTRLSKLDDGLYDAIILASAGLKRLGLADR
IRHCLAPVLSLPAVGQGALGLECRADDEKLLALIQPLQHEETSICVRAERALNAYLEGGC
QVPIAGYATIVNHQLQIEGRVGSVDGKTLLKKQLIGSTDQAEQLGEQLAQDLLDQGAGEL
LKALY
>F4QI49|hydroxymethylbilane synthase|EC 2.5.1.61|Asticcacaulis biprosthecum C19|TrEMBL
MTVLKIGTRGSKLALTQCGWVQRRIVAALGEDVARADEVAPLTVITTQGDRIQDRRLIEA
GGKALFTKEIEDALLRGDIDVAVHSLKDMPAADVPGLSLCAIPVREDPRDAFLSPNYETL
ADLPQGARLGTASMRRQAQALAQRPDLQVIMTRGNVDTRLAKLQAGACDALLLAAAGLNR
LGLSHHIRSHIDPDLFASAPGQGALAIQCRTEDLGAGWMAKVHDVTTFLRIQAERGALEA
LEASCRTAVGAYATLENDQLALFVEALSADGSKRWQRRESLSAPTAQSARDLGLKLGHEI
KTEAGPELIVS
>H5LU41|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC13C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q08TP1|hydroxymethylbilane synthase|EC 2.5.1.61|Stigmatella aurantiaca (strain DW4/3-1)|TrEMBL
MSRLVRIATRQSPLALWQARHVGALLTAQHPGLSVSLVEMTTEGDRFLSAPLSSVGGKGL
FVKEIEQALLDGRADIAVHSLKDMTSVLPEGLMLAAVPVREDPRDAFCSPTGLTLDRLPQ
GARVGTSSLRRSCILRSWRKDLEIVSLRGNVQTRLQKTRDLGLAGTVLAHAGLKRLGLER
EISEVLSPSVSLPAVGQGVLAIQCRTEDAEVRALLGPLEDAVTRVAVTAERALLAKLEGG
CKVPLAGHATVEQGRVHLRGFVGRPDGTQVVAGEVRGTAKEAQALGEALAEDLLSRGAGE
ILRDFGHAGRGPKP
>H0KFW2|hydroxymethylbilane synthase|EC 2.5.1.61|Aggregatibacter actinomycetemcomitans RhAA1|TrEMBL
MTQKNLKIATRQSPLALWQANYVKDRLQQLYPDLNVELVPMVTKGDVILDSPLAKIGGKG
LFVKELENALLNKEADIAVHSMKDVPMQFPQGLGLAVICKREDPRDAFVSNSYRTLAELP
QGAVVGTSSLRRQCQLKKLRPDLDIRSLRGNVGTRLSKLDNGDYDAIILASAGLIRLGLA
ARIASFIDVEQSLPAAGQGAVGIECRTDDVAVQQLLAPLADAETTSCVLAERAMNNRLQG
GCQVPIGGYAVLRDGELYLRALVGSVDGSTIIRAEGKSAVENADVLGMQIAEQLLAQGAD
KILQDIYA
>F7MNZ4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum C str. Stockholm|TrEMBL
MRIVVGSRGSKLALTQTNWVIDKIKQNNPQLNFEIKIISTKGDRIQHMPLDKIGGKGLFV
QEIEEQLISGQIDLAVHSMKDMSTDIPEELKFSYVPIREDYRDVLILNKKYKSIDELPKG
AKIGTGSKRRKYQLLDYRTDLKVVPIRGNVDTRIKKIETENLDGIVLASAGIKRLGLEDK
IDYNIFYLEKDIMLPSPAQGILALEIKRGRKDLENILKSIEHKASTIQAEAERAFLKGVN
GGCHVPIGALCNINKNTIEVTGLLGKEDGSKIIRKTLVGSIDEAEYVGYELAKIILKEIN
>C6SFD5|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis alpha153|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALQDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAIVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
ERIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>D5PBT7|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium parascrofulaceum ATCC BAA-614|TrEMBL
MANVIRIGTRGSLLATTQAGVVRDALIANGHPAELVIITTAGDRSSAPIETLGVGAFTTA
LREAINDGRVDAAVHSHKDLPTADDPRFTIAAIPPRNDPRDVVVARDGLVLGELPPGSLV
GTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTE
TLEPVQMLPAPAQGALAVECRAGDGLAAVLAELDDADTRASVTAERALLAELEAGCSAPV
GAIAEVVESLDEEGRVFEELSLRGCVAALDGSDVIRASGIGTADRARELGVSVAAELFEL
GARELMAEARQDPARGN
>D5PBT7|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium parascrofulaceum ATCC BAA-614|TrEMBL
MANVIRIGTRGSLLATTQAGVVRDALIANGHPAELVIITTAGDRSSAPIETLGVGAFTTA
LREAINDGRVDAAVHSHKDLPTADDPRFTIAAIPPRNDPRDVVVARDGLVLGELPPGSLV
GTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTE
TLEPVQMLPAPAQGALAVECRAGDGLAAVLAELDDADTRASVTAERALLAELEAGCSAPV
GAIAEVVESLDEEGRVFEELSLRGCVAALDGSDVIRASGIGTADRARELGVSVAAELFEL
GARELMAEARQDPARGN
>H8BCF4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 110-21|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>B5ILG5|hydroxymethylbilane synthase|EC 2.5.1.61|Cyanobium sp. PCC 7001|TrEMBL
MAGSTLRIASRRSQLAMVQTHWVRDELAKAHDDLTITIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVDRADIAVHSLKDLPTNLPEGLMLGCITEREDPADALVVHAKHRDKTLA
TLPEGSVVGTSSLRRLAQLRHHFPHLTFKDVRGNVITRLEKLDSGEFDCLILAAAGLGRL
GLGDRIHELIDPSISLHAVGQGALGIECREGDEPVLEQIKVLEHLPTARRCLAERAFLRE
LEGGCQVPIGVNTRFDGAGESGELVLTGMVASLDGQRLIRDEARGPQDDPEAIGIALARS
LRNQGAGEILEEIFASVRPEA
>B3X3X4|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella dysenteriae 1012|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>C2GGB5|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glucuronolyticum ATCC 51866|TrEMBL
MTLRIGTRGSKLATTQAGHVRDALIRAGYDAELTIITTPGDKNLSPVQKIGVGVFTQALR
EAMDRDEIDIAVHSCKDLPTGQPEGLATIYPVRETPCEALIARDGLTLDQLPEGAKVGTG
APRRISQLKALRPDLDIRPLRGNVDTRMGKVTSGELDAVILAHAGLTRIGRGDEATQVFD
PTYLMPAPAQGILAVESRTHVDAISTLIDDHATLSAQAERAVLSTLQAGCTAPLAAYSTV
SGDEITLTAGAFALDGSKQIVETATGTDPVALGTSVAEKLRACGAEEIIR
>C2GGB5|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glucuronolyticum ATCC 51866|TrEMBL
MTLRIGTRGSKLATTQAGHVRDALIRAGYDAELTIITTPGDKNLSPVQKIGVGVFTQALR
EAMDRDEIDIAVHSCKDLPTGQPEGLATIYPVRETPCEALIARDGLTLDQLPEGAKVGTG
APRRISQLKALRPDLDIRPLRGNVDTRMGKVTSGELDAVILAHAGLTRIGRGDEATQVFD
PTYLMPAPAQGILAVESRTHVDAISTLIDDHATLSAQAERAVLSTLQAGCTAPLAAYSTV
SGDEITLTAGAFALDGSKQIVETATGTDPVALGTSVAEKLRACGAEEIIR
>F9C317|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-38A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>H3XJD0|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-55|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>D0L4A1|hydroxymethylbilane synthase|EC 2.5.1.61|Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667)|TrEMBL
MSGATPGPIRIGTRGSLLATTQAQTIADALTEAGHPAELVIIRTAGDDSAAPVAEIGVGV
FTTAIRIALHNREVDVAVHSYKDLPTADEPGLYIAAVPPREDPRDALVSRDNMVLGELPP
GSTIGTSAPRRVAQLRALGLGLEIRPLRGNLDSRLGKVASGELDAVVVARAGLVRIGRAD
EVTESFDPVVLLPAPAQGALAVECRSDDAQLVRILAELDDESTRAAIDAERAVLAALEAG
CTAPIGAIAEVVESIDDDGRIFAELSLRAAVAAEDGSDVIRASVVGPVDRAAQLGADLAA
ELLELGAGDLVTP
>C2IX98|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae TMA 21|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVDDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>D6DP62|hydroxymethylbilane synthase|EC 2.5.1.61|Enterobacter cloacae|TrEMBL
MVTRGDVILDTPLAKVGGKGLFVKELELALLENRADIAVHSMKDVPVEFPEGLGLVTICE
REDPRDAFVSNRYDSLDALPAGSVVGTSSLRRQCQLAERRPDLVIRSLRGNVGTRLGKLD
NGDYDAIILAVAGLKRLGLEERIRVALPPELSLPAVGQGAVGIECRLVDARTQALLAPLN
HDDTAVRVKAERAMNTRLEGGCQVPIGSYAELTDGELWLRALVGAPDGSQMVRGERRGKP
QDAEALGVSLAEELLNNGAREILAEVYNGEPPA
>B1VT95|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)|TrEMBL
MTDNSSPGARNSAPLRLGTRRSKLAMAQSGLVAEAVREVTGRAVELVEITTYGDTSREHL
AQIGGTGVFVAALREALVRGEVDFAVHSLKDLPTFQPDDLVLAAVPQREDPRDALIARDG
LTFGQLPEGARVGTGSPRRMAQLNAYARSHGLRIETVPIRGNVDTRIGFVRDGELDAVVL
AAAGLSRLGRSGEVTEFLPVDTVLPAPGQGALAIECAASSADLAAALAELDDPYTRAAVT
AERALLAALEAGCSAPVGALADLLVDGQVVNELRLRGVVGTTDGSSLVQLSTTGPVPTSH
DDAAAIGRELAAEMLAKGAAGLMGERAL
>C6WNG2|hydroxymethylbilane synthase|EC 2.5.1.61|Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)|TrEMBL
MNRTLRIGTRGSALALAQTGTVAEALRAAGAQVEIVTVSTPGDRSHAPIAEIGIGVFTSA
LRDALAHGEVDVAVHSYKDLPTAPDTRLSLAAIPQREDPRDALVARDGLTLGELPPGSKV
GTGSPRRATQLAALGLGLEILPIRGNIDSRMARVFDGELDAVVLARAGISRLGRVENITE
VLDPIQMLPAPAQGALAIECRVDDVDTEHLLRSTLDDSASRAAVTAERAMLAALEAGCSA
PVGALADVVEDLDDEGAAVLRISLRGVVAAEDGDLLRASATGDLTAAEELGRALAAELLD
LSGHAAARSAGRS
>I4VUI0|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodanobacter spathiphylli B39|TrEMBL
MNPSTLRIATRKSALALWQAEHVAALLRVAHPGLLVELVPMSTRGDEILDKPLATIGGKG
LFLKELEVAMLEGRADLAVHSLKDVPAELEPGFVLPAILPRADAADAFVSNDHAELASLP
QGARVGTSSLRRQAQLRALRPDLRLLDLRGNVGTRLGKLDAGDYDAIVLACAGLERLGLA
ARIRSRLAAPDWLPAPGQAAIAIEARADQPAVLALLAALDDADTRLTVTAERAMNHALGG
SCTVPVGAWCMLGEHGLHLRGLVGDANSGRLLHAEAASPGEQAEALGRQVAEALLAQGAG
ELLG
>C7P203|hydroxymethylbilane synthase|EC 2.5.1.61|Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541)|TrEMBL
MTTATTVRLATRGSDLALRQAATVTETLEARGYTVEIVEVETTGDQIRDELIHRLGKTGA
FVRSLDEQVVDGEVDAAVHSMKDVPTEQPEELVVAGVPQRESPDDVLVTPDGATVDELPD
GATVGTSSLRRKAQLLAERPDLDVQPLRGNVDTRIEKLLAPTLQSEHEERSEAEKEQKEK
VDDEEYEFPYEQDVETWFDGLTEIERQALGREVETAYDAVVLARAGLERAGLLHHVEYQS
LPTGTFVPAPGQGALAVTATDDEFARELNDALDHPRSRAETTVERTVLDELGGGCVAPLG
VHAILQGSVIRTTVRVLDQAGEREVAATRDLSADRHVDDARAFAADLAEQGGADLIEQAK
RAGEGGDAATAQGAGDE
>H3X3V6|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-3|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>Q7P7E7|hydroxymethylbilane synthase|EC 2.5.1.61|Fusobacterium nucleatum subsp. vincentii ATCC 49256|TrEMBL
MKKNIIIGSRGSILALAQANLIKDKLQINYPNLTFTIKEIVTSGDKDLKSNWENSDISLK
SFFTKEIEQELLDGDIDIAVHSMKDMPAISPKGLICGAIPDREDARDVLVSKNGFLVTLP
QGAKVGTSSLRRAMNLKAIRPDFEIKHLRGNIHTRLKKLETEDYDAIVLAAAGLKRTGLA
DKITEYLNGEVFPPAPAQGVLYIQCRENDEEIKKILKSIHNKAVAKIVEIEREFSKIFDG
GCHTPMGCYSQINGDKIKFTAVYLDEGKQIKAVVEDDLAKGKEIAYMAAEEIKNKINKGT
IQ
>E3G3Y1|hydroxymethylbilane synthase|EC 2.5.1.61|Enterobacter cloacae (strain SCF1)|TrEMBL
MTVTSMLDKVLRIATRQSPLALWQAHYVKDRLTACHPGLQVELVPMVTRGDVILDTPLAK
VGGKGLFVKELELALLEHRADIAVHSMKDVPVEFPQGLGLTTICEREDPRDAFVSNQYAS
LDALPAGSIVGTSSLRRQCQLAAQRPDLVIRSLRGNVGTRLSKLDNGDYDAIILAVAGLK
RLGLESRIRQALSPEQSLPAVGQGAVGIECRLDDDATRALLAPLNHPETAVRVGAERAMN
TRLEGGCQVPIGSYAELQGGELWLRALVGAPDGSRMVRGERRGTPEEAERLGVSLAEELL
DNGAREILAEVYNGEAPQ
>F5MTW1|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri K-218|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>Q4HHN9|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli RM2228|TrEMBL
MKELVIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEQILEFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSEFKGFGESLAKEFIAKGAKEI
LKKAESMI
>E2MUZ8|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium amycolatum SK46|TrEMBL
MPDPATIRIGTRGSELATTQAGHVRDALIELGQPAELVIVKTAGDHNRHDPVEKIGIGVF
TQALRHALREGVCDIIVHSFKDLPTVPEDDMMVAAVPERVDPREALISRDATPLMDLPEG
ARVGTSAPRRVSQLRALRSDLELVPLRGNIETRMGRVSEDLDAVILARAGLERTGRLGEI
AESLDVDVLMPAPAQGALALECRTADREIVDILRKIDHPVSHARAVAERAVLNKLEAGCT
APVAAYATVSDSGELTLQAGVFALDGSRQLLETATANVDKADELGRKVAAALLERGAHEV
MGDTLRESQK
>E2MUZ8|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium amycolatum SK46|TrEMBL
MPDPATIRIGTRGSELATTQAGHVRDALIELGQPAELVIVKTAGDHNRHDPVEKIGIGVF
TQALRHALREGVCDIIVHSFKDLPTVPEDDMMVAAVPERVDPREALISRDATPLMDLPEG
ARVGTSAPRRVSQLRALRSDLELVPLRGNIETRMGRVSEDLDAVILARAGLERTGRLGEI
AESLDVDVLMPAPAQGALALECRTADREIVDILRKIDHPVSHARAVAERAVLNKLEAGCT
APVAAYATVSDSGELTLQAGVFALDGSRQLLETATANVDKADELGRKVAAALLERGAHEV
MGDTLRESQK
>G7QV48|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium bovis BCG str. Mexico|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>G7QV48|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium bovis BCG str. Mexico|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>B1XVG8|hydroxymethylbilane synthase|EC 2.5.1.61|Polynucleobacter necessarius subsp. necessarius (strain STIR1)|TrEMBL
MSQTLNSSPQSAPKRLVIASRESRLAMWQAEHVQDCLKKLYPDCDVQILGMTTRGDQILD
RALSKVGGKGLFVKELETALEDGRADLAVHSLKDVPMVMPEGFDLACVMAREDARDAFVS
NDYASLEDLPIGAIVGTSSLRRESVLRAKFPHLVIQPLRGNLDTRMGKLDKGEYQAIILA
AAGLKRLGLESRIRAFLPYDPYTPAAGQGALGIETLSKHPNIKQWLAPLNDLPTLFAVSA
ERMVSRQLGGSCEVPLAAHAVRDQNQMQIRSFVASTDGKAICLAHGSALVESVEDAEALG
LAVAQDLLSQGAADLIPALPK
>D8DTU9|hydroxymethylbilane synthase|EC 2.5.1.61|Prevotella bryantii B14|TrEMBL
MPQNKELAPIRVIARRSKLSQLQVAEVFNRLKDIPYTIVFTDTFGDKRLDLSLLNGEAPD
DMFTRELDWALLHDDADIAIHSAKDLPEHLHPDLEVIALYEAFDKTDALVSRDHIKLMDL
PAGSTVGTSSPLRKKGLSELRPDLKIVGIRGCIEDRVAQVRDGKLDCAIVATCALKRLGM
EDEITEILPFPTHPMQGRLAITAKRGEAAENLKKWFAPGNILNETI
>H5KLG2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC12E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F2BD17|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria bacilliformis ATCC BAA-1200|TrEMBL
MNAPDKLTIASRQSALAMWQAEHIKARLHALYPACDIRILGLTTRGDQILDRTLSKIGGK
GLFIKELEQALHDGRADLAVHSIKDVPMELPEGFLLAAIGERASPFDAFVSNRHNTLAAL
PAGAVVGTSSLRREAQIRARHPHLTVKPLRGNVQTRLAKLDNGEYDAIILAAAGLQRLGL
NGRIREILSPDECLPAAGQGALGIEIAEHRSDLLPLLAPLNHAETAACVTAERTLAQALG
GSCQIPLAAYCTSDEGLLTLRGLVGHPDGSVLIEAAAQAPAAYARTLGRAVAKRLADQDA
EALIDAVLAGQNTAPHG
>A5L4B1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrionales bacterium SWAT-3|TrEMBL
MVGLGYYRTYIGNTMTNSAPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKG
DIILDTPLAKVGGKGLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPR
DAFVSNTYNNIDELPQGAVVGTCSLRRQCQLLEYRPDLIIKELRGNVGTRLGKLDDGQYD
AIVLAAAGLKRLELEERIRSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHQDTA
DRVLCERAMNLTLEGGCQVPIGSYSLLDGDNIWLRALVGEPDGSKMVRGEISGPRKDAEA
LGVTLANQLLDDGAREILTKLYADQE
>B1RIF2|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium perfringens CPE str. F4969|TrEMBL
MELIIATRKSKLAQVQTEKVMELLKEKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVK
EIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGAR
IGTSSIRRAEQLKLFRDDLEIVPIRGNIQTRIKKITEENLDGIILAAAGLKRLGMEEVIS
DYFDPKVFLPAIGQGALGIECLKGGEFNDYFKALDSKEVRTTVEAERSFMKVLNGGCHSL
IGAYSEVKDNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILGEV
>B1BE63|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum C str. Eklund|TrEMBL
MKIVVGSRGSKLALTQTNWIINEIKQNYPQIQFEVKIISTKGDRIQHIALDKIGDKGLFV
KEIEEQLISGEIDMAVHSMKDMSTDIPEELKFSYVPKREDYRDVLILNKKYNSIDELPMN
ARIGTGSKRRRYQLLQYRDDLNIVPIRGNVETRINKIETENLHGVVLAVAGIKRLNIEEK
LDYNIFYLNENIMLPSPAQGILALEIKKHREDLEKILKSIEDRNSTIQAIAERAFLKGVN
GGCHVPIGAICNINKDNIEVTGLLGKEDGSKIIRKSLGGKIEDAEKIGYELAEIVLKEIN
>Q3YVG2|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella sonnei (strain Ss046)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAKQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F7TLI1|hydroxymethylbilane synthase|EC 2.5.1.61|Pasteurella multocida subsp. multocida str. Anand1_goat|TrEMBL
MRIATRQSPLALWQANYVKACLEKIHAGLVVELVPMVTKGDVILDTPLAKIGGKGLFVKE
LEQALLKGEADIAVHSMKDVPMQFPAGLMLSTICQREDPRDAFVSNSYRTLMELPAGAVV
GTSSLRRQCQLKQLRPDLHIHSLRGNVGTRLAKLDNGDYDAIILAAAGLIRLGQQQRITS
LIDVTQCLPAAGQGAVGIECRQEAEIELLLAPLADPETTACVLAERAMNRHLQGGCQVPI
AGYAIIEEGQLFLRALVGEVDGSSILRAEGRSAVADAETLGIQVAEKLLQQGADKILQTL
YSN
>F0PZ09|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus thuringiensis subsp. finitimus (strain YBT-020)|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLINQGAKEL
ILAANKGQQ
>H7Z0L1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 9081|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>H7S6N4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 2698|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>E4RQ21|hydroxymethylbilane synthase|EC 2.5.1.61|Leadbetterella byssophila (strain DSM 17132 / KACC 11308 / 4M15)|TrEMBL
MKIRIGTRVSLLAMWQANYIKSRLEAAGAETEIVGMETKGDKVLDVALSKIGSKGVFTEE
LEEKLLNGEIHIAVHSAKDMQSSLAEDFELIAFTEREYPGDVLVADRALDLSAPITIGTS
SVRRIAFFKKHYPHIKLVNMRGNLQTRIQKMRSGQCDGLALAYAGVHRMEYDELIVHRFP
LDQFIPPVGQGTVTVEIAKNLDENIKTFVKNTCNDENTYKCLQAERAFLKEMNGGCSIPV
FGHATLEGEEILFKGGITNLEGTEEVSMEFRGTDPILLGQHAAEQVLQNGGAEILKQIRA
>H0SEK6|hydroxymethylbilane synthase|EC 2.5.1.61|Bradyrhizobium sp. ORS 375|TrEMBL
MALAQTEEIGRRLQAAIPSLDIEIVKFETTGDSDQTSKLLTHGGKGGAFVAEIRRAMLDG
RLHAAMHSLKDMPGNEETPGLVIAALLSRDPPGDVLVLRKGLALEDFRKDGGRGFKIGTN
AVRRAAYARRLFPHAELIHFRGAADTRIRKLDNGELQRLPDGGAVGPADALIMARSGLER
VGLADRASYEFPVADMLPAAGQGIVAVECPAADFETRRILSTIDDAAARACADAEREVLW
VLNGHCNSPIAGFSTIEGGEMILTASVLDEDGGRFIEAQRAGPADRPRELGRAVGLELLG
NGAAALIERSRPR
>I2YG48|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 3.2303|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>H5QLL3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC15C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHKTALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H5M856|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC13D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H2AAM8|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus amyloliquefaciens subsp. plantarum CAU B946|TrEMBL
MRTIKVGSRRSKLAMTQTKWVINKLKELNPSYDFEIREIVTKGDRILDVTLSKVGGKGLF
VKEIEQALLHQEIDMAVHSMKDMPAVLPEGLVIGCIPKREDPRDALISKGHQKLDGIKEG
GIIGTSSLRRSAQILAERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKDD
VVSEFLEPDRCLPAVGQGALAIECRESDEELLKLFAQFTDEYTQRTVAAERAFLHAMEGG
CQVPIAGYASVNDRDEVELVGLVASPDGKTIYKETAAGHDPEEIGKRCAAMMSEKGAKAL
IDSVKQELEQDGK
>H5GZ80|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC11B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H3WBW1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU127|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>E7SHC8|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella dysenteriae CDC 74-1112|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>I3ZHV2|hydroxymethylbilane synthase|EC 2.5.1.61|Terriglobus roseus DSM 18391|TrEMBL
MQPALRQRGCESRLGIPRRAQYDGRMHLRIGSRGSRLALWQSNHIAAHLRALGHTAEVTI
IRTTGDRLQDPAFAATVLGPDGRIPANIDGKGIFIKEIEEALEAGTIDLAVHSLKDLPTQ
LDARFTLAAIPERADPRDVLLVPEWLQIHTLPANARIGTTSPRRIAQLRALNPEFQFVAI
RGNIDTRIRKLGRGDCDALVLAAAGLDRLGPRLLKPVELDPQHPEYGRTPHIECITHPEH
DHLGEHFDAKGHEHGEELPGQADWIRQRFDPEMMCPAPGQGALAIETRANDAATIAAIQP
LDNAETRYAVEAERWLLHALGGGCALPVGALCTHADGGATLLATVVSPDGDAMANVMLFA
TPGESAENFGTRAANDLIAQGARELLAGEFATADAE
>H8NEF7|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia prowazekii str. GvV257|TrEMBL
MINSIRIGTRNSTLALIQTNLVIEQIKQIFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGKIPVELVIAAVLEREDPRDVLVCLNYQSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDAIILSYAGLKRLNVFN
QKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPERAFLEYLDA
NCSTPIAAYAQYLDAYNIQIDFMLGNLDCTKIIFQTEITNIKTSKICGIKAAKMMLAQQ
>I5YJ52|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC1734|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B3A0Y5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC4401|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>H4JFM3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC1D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C9X131|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup C (strain 8013)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>A2SK66|hydroxymethylbilane synthase|EC 2.5.1.61|Methylibium petroleiphilum (strain PM1)|TrEMBL
MEASTQAWVIATRESRLALWQAEHVRALLGSRLVEPVELLGMTTRGDQILDRTLSKVGGK
GLFVKELETALEAGDAHLAVHSLKDVPMDLPAGFVLAAVLEREDPRDAWVSPRYADLAAL
PAGAVVGTSSLRRLSQLRARRPDLRIEPLRGNLDTRLRKLDEGQYDAIVLAAAGLKRLGL
AERIRSVFEADAMIPAAGQGALGIELRADAPERHPALWAALRALTHEPSWLAVHAERAVS
RALGGSCSMPLAAHAQWQADGRLVLRAALGSVAEAAPALVHAEAGAAVADTAAAEALGLA
VAQQLRQRGGDALLAAL
>G0LUR2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus LGA251|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAVHSLKDVPSVIPKGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>F2BK83|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK1|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKKLHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRQLLATVQDEKTAAEVAVERVVLAQM
NADCTFPIAAFAQKNGQDYQLEAMLAKEDGQCVFVSLKGQDGQQLAEQAVRQLADKGAVG
MPWLKK
>F4H671|hydroxymethylbilane synthase|EC 2.5.1.61|Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)|TrEMBL
MPQQVRIGTRASTLALTQTGHVADALAAHGGLAIETVRVRTDGDRLTGSLASLGGAGVFV
TALRDALLDGRCDVAVHSLKDLPTADAPGLVLAAVPPREDPRDALCARDGLTLADLPRGA
RVGTGSPRRAAQLLAARPDLDVVDIRGNVDTRLGRVAGSPTGPGDLDAVVLARAGLARIG
RLEAVTELFGPDVMLPAPGQGALAVETRAAGLTTDLAGPLHAALAALDDRPTRLAVLAER
ALLARLEAGCAAPVGTLATLDADGTLTLDAVVVRTDGTASLRRRARTALPGTAAQDVVAA
RALGTDLADALLADGAADLADLGASR
>F5N8P7|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri VA-6|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>A3K9C2|hydroxymethylbilane synthase|EC 2.5.1.61|Sagittula stellata E-37|TrEMBL
MTMPTPNSPLKIGTRGSPLALAQAFETRERLMAAFSLPEDAFEICIIKTTGDDRAMIAAD
RPLKEIGNKGLFTKEIEEALVAGRIDIAVHSMKDMPTEQPEGLILDCYLPREDPRDAFIC
HDHGSIHDLPVGAVVGSSSLRRRAQLLHRRPDLDVVEFRGNLQTRLKKLSDGVATATFLA
CAGLNRMKIPGVPMFPIAEVDMLPAIAQGAIGIERRIDDATTQEMLAAIHDHDTGLRLAA
ERAFLARLDGSCETPIAGLAELDGATLHLRGEILRPDGSISHAGEISGAATEGAALGRTL
ADDLLSRAGEGFFDWH
>F3K3Z6|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. tabaci str. ATCC 11528|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDELP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
NRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPAGSVLLHAEARAPQTSAQALGVQVAEALLAQGAA
DILKAVYGEANIE
>I1E2B8|hydroxymethylbilane synthase|EC 2.5.1.61|Rheinheimera nanhaiensis E407-8|TrEMBL
MTTVRIATRKSALALWQAEYVKAELLRHHPQLQVELVPMSTQGDKILDTPLAKIGGKGLF
VKELEQAMLDGRADIAVHSMKDVPVEFPPGLMLHTICPRENPLDAFVSNQFKSLDELPKG
AVVGTSSLRRQCQLKALRPDLTVRDLRGNVNTRLAKLDNGEFAAIILAAAGLIRLGFAQR
IASLLPVELSLPANGQGAVGIECRSDDKAVQQLLAPLEHAGTRACVLAERAMNRKLQGGC
QVPIGAFAVLEGDTLWLRGLVGAVDGSEIIRDEIRGPVQDAEQLGTELAAKLLAHGAGRI
LQAVYQAAP
>Q1GDK5|hydroxymethylbilane synthase|EC 2.5.1.61|Silicibacter sp. (strain TM1040)|TrEMBL
MTLTLPSPASPLKIGTRGSPLALAQAYETRDRLARAFELEPTAFDIVVIKTTGDNRAMID
ADRPLKEIGNKGLFTKEIEEALLSGGIDIAVHSMKDMPTLQPEGLTLDCYLPREDVRDAF
VSPGIHSIADLPEGAVVGTSSLRRRAQLLHRRPDLQVVEFRGNVQTRLQKLENGVASATF
LAMAGLRRLDMAEAVPATPISVDDMLPAVAQGAIGIERRSSDITTAAMLEAIHHAETSLR
LAAERAFLAALDGSCETPIAALADLSGGTIQLRGQILRPDGSEALSDEQDGAIEDGAELG
RQMGETLRARAGAGFFAH
>H4FV99|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-157|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>G0GYF5|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia heilongjiangensis (strain ATCC VR-1524 / 054)|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQITQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMIGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGIIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDADPRHLSKLTYREAFAENTEALATATHKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>B5YY51|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 (strain EC4115 / EHEC)|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>A7ZU07|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O139:H28 (strain E24377A / ETEC)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F6CRK6|hydroxymethylbilane synthase|EC 2.5.1.61|Marinomonas posidonica (strain CECT 7376 / NCIMB 14433 / IVIA-Po-181)|TrEMBL
MKDKIVIATRESQLALWQANNVKAQLESLYPDLTVELLGMTTKGDQILDSPLSKIGGKGL
FVKELEAALLDRRADIAVHSMKDVPMAFPEGLGLAVICEREDPSDAFVSNQYSSLDDLPA
GAVVGTSSLRRSCQLKMHRPDLIIKDLRGNVNTRLRKMDEGEYDAIILATAGLLRLEMRD
RIRQKIPAEMSLPAGGQGAMGIECRADDRPTLELLVPLQHEETTYRVTAERALNERLNGG
CQAPIACFAILQQDEIWLRGLVGSPDGKTMIQSDIRGHKDNAKQLGVTLAEELLSRGANT
ILDAIYQ
>H7SNZ2|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 86119|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>A3YZH7|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. WH 5701|TrEMBL
MAGTTLRIASRRSQLAMVQTHWVRDELTRAHPDLEISIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVDRADIAVHSLKDLPTNLPDGLMLGCITEREDPADALVLHERHRGCSLE
TLPEGSVVGTSSLRRLAQLRHHFPHFQFKDVRGNVITRLEKLDSGDYDCLILAAAGLGRL
GLGHRIDALIDPSISLHAVGQGALGIECRHGDSAVLEQIKVLEHLPTARRCLAERAFLRQ
LEGGCQVPIGVNSRFEGEELVLTGMVASLDGLRLIRDEARGPQQDPEAVGTSLAQLLRSQ
GAGEILEEIFAEVRPEA
>E9SYT6|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus equi ATCC 33707|TrEMBL
MSTDAAASPATDLNVGPDSRTLRIGTRGSLLATTQAGHVRDALIAAGHPAELVIIKTKGD
VTAGPVQRIGVGVFVAELREALVAGEVDVAVHSYKDLPTAQPDDLTIAAVPTREDPRDAL
VARDGLVLGELPPGSRIGTSAPRRRAQLRAMGLGLEIEPLRGNIDTRLGKVASGELDAIV
IARAGLSRIGRTERITETLEPVQMLPAPSQGALAVECRSDNPDLIAILGELDDHATRAAV
VAERALLAELEAGCTAPVGAIAEVVESLDDDGRVFEELSIRGCAAAIDGSDVIRASLVGS
PERADELGRAVARELLDLGARDLMTIAEDGDADA
>E9SYT6|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus equi ATCC 33707|TrEMBL
MSTDAAASPATDLNVGPDSRTLRIGTRGSLLATTQAGHVRDALIAAGHPAELVIIKTKGD
VTAGPVQRIGVGVFVAELREALVAGEVDVAVHSYKDLPTAQPDDLTIAAVPTREDPRDAL
VARDGLVLGELPPGSRIGTSAPRRRAQLRAMGLGLEIEPLRGNIDTRLGKVASGELDAIV
IARAGLSRIGRTERITETLEPVQMLPAPSQGALAVECRSDNPDLIAILGELDDHATRAAV
VAERALLAELEAGCTAPVGAIAEVVESLDDDGRVFEELSIRGCAAAIDGSDVIRASLVGS
PERADELGRAVARELLDLGARDLMTIAEDGDADA
>F9R6N8|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio sp. N418|TrEMBL
MTHSSPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGSVVGTCSLRRQCQIKERRPDIIIKDLRGNVGTRLGKLDAGEYDAIVLAAAGLKRLKL
EERIRSFMEAEESLPAVGQGAVGIECRLDDERLIKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYSLLDGDQIWLRALVGEPDGSQIIRGEIQGPREQAEELGITLANQLLDQGA
RDILTRLYAEHE
>I5MDA2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA39|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>F7YQ91|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio anguillarum (strain ATCC 68554 / 775)|TrEMBL
MTNLCYLFINPSQRRSSSKPFIAGMIGLNHPLPTLGIIMTHATPIRIATRKSPLALWQAY
YVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGKGLFVKELEVAMLEGRADLAVHS
MKDVPVDFPQGLGLVTICEREDPRDAFVSNTYQSIEQLPQGAIVGTCSLRRQCQLKAYRP
DLVIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKLEDRIRSIIEPEQSLPAVGQGAV
GIECRLDDERLRALLAPLNHSDTADRVKCERAMNLTLEGGCQVPIGSYALLDGDHIWLRA
LVGEPDGSKIVQGEIRGHRSDAEQLGITLAHQLLNDGARDILSKLYCEHE
>H7CWG7|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium perfringens F262|TrEMBL
MELIIATRKSKLAQVQTEKVMELLKEKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVK
EIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGAR
IGTSSIRRAEQLKLFRDDLEIVPIRGNVQTRIKKITEENLDGIILAAAGLKRLGMEDVIS
DYFDPKVFLPAIGQGALGIECLKGGEFNDYFKALDSKEVRNTVEAERSFMKVLNGGCHSL
IGAYSEVKGNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILGEV
>I2SQU4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 1.2264|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>I0XQ71|hydroxymethylbilane synthase|EC 2.5.1.61|Leptospira licerasiae serovar Varillal str. VAR 010|TrEMBL
MSDVLRIGSRKSSLAKLQTCLVQDQLRKLYPELELQLFFKESSGDQDLTTPLWKMGSRGV
FTQDLTKELVKGNVDIVVHSFKDLDLEGHDGTEILMVLPRADQRDVLLFKRSSYENPPKE
IKIHSSSPRREYNLSAFLPSALPSRLQNLPISFHPVRGNVQTRLHKWKSDPEVSGIVVAK
AALDRLLSENFSFSSTEEYSEVRKEIRSAIANELFMVLPLSKNPNAPAQGALAAEIRKGD
EKTKRLLLPLLNGKEEAAVLEERKILSYFGGGCHQKIGVSVILGGPADFLFVRGKTDSGS
ELDAFDRWNGEELPLPSSLDLIFPKPKQGFRMKRSPLQTSLPKEKFWFVSRADSLPKDWE
LPGPETIFIVAGAKTWEKLASRDVWVNGSTDGLGEEDAKTIVSFYESNPDFIKLTHEESD
IIEGVWKRFVTYKVDFDSEQPDLSGYSHFFWMSASQFDRAYKKNPEIGSRIHSCGTGATY
KYIRKILGDSAKIFAFPNFESWERACRGEVQDFFAKRGAV
>F4LUU2|hydroxymethylbilane synthase|EC 2.5.1.61|Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1)|TrEMBL
MKKIVKVGSRQSQLALVQTELVISQLKEHFPQWDFKLITVKTTGDKFLNSNMYELGKGAF
VKEIEEALLSGAIDMAVHSLKDVPHELPEGLAISAITRREDPRDVFISADDRRFSELDTG
AKIGTSSMRRMCELNKLRQDIECVPIRGNINTRIKKIKTCGLDGIVLAAAGVKRLGMENL
ITDYFSPDEIVPAVGQGALAVETRADDEMSLFVKYINDDETTCATGAERAFMKVVGGSCK
QPMGAYAEIFDDALKLIGMIERDGVVKWGKLEGRKSEAEQIGIRLAEELGGKL
>G0CM98|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium ulcerans 809|TrEMBL
MTFTIGTRGSLLATTQSGHVRDALAAHGYSAELSIVTTPGDVNMAPVERIGVGIFTQALR
EVLVEGGCDIAVHSFKDLPTQRDPRFHLIVPERADARDCLVARDGLTLEKLPQGARIGTG
APRRISQVKALRPDVECVPLRGNIDTRMGKVFSGELDAVVLAYAGLSRVGRGDEATEVFN
PDRFLPAPAQGALAIECRIDDAAAIAAINSIRDVDDETCALAERVVLNRLEAGCTAPVAA
HSVISGQELHVTGAVVSLNGRKVLRTTMTGAVTEAVAIGEAVAAKLIRDGAAEVLS
>G0CM98|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium ulcerans 809|TrEMBL
MTFTIGTRGSLLATTQSGHVRDALAAHGYSAELSIVTTPGDVNMAPVERIGVGIFTQALR
EVLVEGGCDIAVHSFKDLPTQRDPRFHLIVPERADARDCLVARDGLTLEKLPQGARIGTG
APRRISQVKALRPDVECVPLRGNIDTRMGKVFSGELDAVVLAYAGLSRVGRGDEATEVFN
PDRFLPAPAQGALAIECRIDDAAAIAAINSIRDVDDETCALAERVVLNRLEAGCTAPVAA
HSVISGQELHVTGAVVSLNGRKVLRTTMTGAVTEAVAIGEAVAAKLIRDGAAEVLS
>E0VQB4|hydroxymethylbilane synthase|EC 2.5.1.61|Pediculus humanus subsp. corporis|TrEMBL
MTDSNLLKVGSRKSQLALSQTQIIVNQLKENFPDLKFDIVTMLTTGDKILDKPLPKIGEK
SLFTKELEAALEKNEVDFVVHSLKDLPTSLPPNLTIGAILKREDPRDALVVNKNLNFKNV
SSLPESSVIGTSSLRRCAQLCRNYPNLKVENIRGNLNTRLKKLDEGDKYTGIVLAAAGLK
RLKYDDRITQILEPNEMLYAVGQGALAVECNKNNEKVLDILEVLNDHSTILRVIAERSFL
KTLGGGCSAPVAVSTKLEEKELYLTGAVWSLNGEKHIQKTKSVTISSDEPLRKKSRVMGE
SHAEITARNISNNDLNLSENLGILLAQDLIKLGALNIISEAKSINEIPNESPKEKK
>E3E9X9|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus polymyxa (strain SC2)|TrEMBL
MRTIVVGSRQSALALTQTGHVIEDLNALCAEHGLDLQFVIKKILTKGDRILDVTLSKVGG
KGLFVKEIEQAMLAGEIDMAVHSMKDMPSELPEGLVNGAVPRREDPRDCLITLGAKSLED
LPSGAKVGTSSLRRASQIKSMRPDLQLEPVRGNIDSRLKKLETEGFDAIILAAAGLHRMG
WKDRITSYIPEEACLPAVGQGALGIECRASDEELLALLRLYNHQDTSATVEAERTFLGVL
NGGCQVPIGAHAVWAGQEISLTGMVGSPDGEVILKETLQGNDPQKLGEAVAASLIAKGAE
QILAQVRG
>D6U6V2|hydroxymethylbilane synthase|EC 2.5.1.61|Ktedonobacter racemifer DSM 44963|TrEMBL
MIIMKRITIGTRASKLAMIQTQWIIERIHQQWPGLEIAIEQIRTTGDRVTSVPLSRIGGD
GVFVTEIESALQERRIDIAVHSLKDLPTAQPEGLCVLTPGPREDVRDVLVSKGDLHISAR
GTLEGITPGRAPRIGTCSLRRTAQIRHLCPDAEILSLRGNVDTRLRKLEAGEYDAIILAA
AGLHRLDLQGTLEGKLSYFPVAQMLPAPGQGALGLEIRDEPAFRELLAPLQDRNVQAATS
AERMFMRRLGAGCYLPVAAHAHIIDERLVLRGLVTSLDGQRRILVQQETGWNAYAFLENA
ERLGIELAEIALAQGAHDIIAELDGSRVQEQQHV
>A6UN91|hydroxymethylbilane synthase|EC 2.5.1.61|Methanococcus vannielii (strain SB / ATCC 35089 / DSM 1224)|TrEMBL
MKLRIGTRGSKLAMIQTKYIASLLNELGVETEIIIIKTTGDKDQNKKLADLGIGVFTKEL
DNKMLENEIDIAVHSLKDVPTLWSDELQITATPKRESPDDLILWNKNSNFNIEYDELIVG
TSSIRRTAFLELSNPNLKVKLLRGNVATRIDKLRNNEYDGIIMAKAGLIRQGIDLSDFNY
EKLEILPAPAQGVIGVASRKKDYEINEILEKINDKKTYLEAVAERWSLKEYGGGCQAPFG
AFAFYDFDEGILTLKCDLVKEIHGKKISISKEGFVYCNVNDVELSKDLGKRVGLSFKESD
IFEI
>H7RL70|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 2680|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKILKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>G2CBJ8|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli STEC_MHI813|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H7Z8T0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 9217|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>B4AS27|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella novicida FTE|TrEMBL
MKQITIASRESKLALWQTNFVKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEIAMLNNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
IVGTSSLRRKAQLLHYRDDLEIRDLRGNVQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>F8M1X0|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium africanum (strain GM041182)|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>Q4EQ64|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 1/2a str. F6854|TrEMBL
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEAIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNQVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPEVCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEFVQFKGLVGNADGSIILESEQVGANPSEIGNKVAEDLLSEGAD
TIIKELRNV
>H6PU46|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia philipii (strain 364D)|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDVNCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>H4JUL1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC1E|TrEMBL
MVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICE
REDPRDAFVSNTYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALN
HHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAP
QDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>G8PEN0|hydroxymethylbilane synthase|EC 2.5.1.61|Pediococcus claussenii (strain ATCC BAA-344 / DSM 14800 / JCM 18046 / KCTC 3811 / P06)|TrEMBL
MKKIIRVGTRKSILAVRQTNLVIEQLKENSPGVDFEIVNITTLGDRDYTTNIKMIYGKGI
FVTEIEDALRTGKIDLAVHSLKDLLPETPQDLSLSSIPTRESPYDCLLTKTKIQSIQDLP
EHARIGTSSIRRISELKHIRSDIEVVPIRGNLDTRIRKIDEMNLEGIVVAEAGLNRLNPE
LKQVYRSPAILELIPSAGQGALAIETRKDDDFVCSIVKKIHDLRTFDEVKAERELLASFG
GTCNFPVGSFAIQNDKTIQLFGSISSYDGTDWIDTVIERNIKQSQNIASEVYQKLLAMGA
DRILKEIKENENE
>H8BWC2|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1213|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>O69104|hydroxymethylbilane synthase|EC 2.5.1.61|Brevibacillus brevis|TrEMBL
MGKWKVGTRRSKLALTQTNWVVDKLKGFAPEADFELHEIVTKGDRILDVTLSKVGGKGLF
VKEIEQSLFDKETDFAVHSLKDMPAELPEGLVIGAIPKRVDPRDVLLSKDGKTLDELPQG
ALVGTSTLRRSAQILAHRPDIQIESLRGNID
>H8B1U6|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1997-14|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESILRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>F2JGZ9|hydroxymethylbilane synthase|EC 2.5.1.61|Cellulosilyticum lentocellum (strain ATCC 49066 / DSM 5427 / NCIMB 11756 / RHM5)|TrEMBL
MKVVIGTRGSRLALTQTKWVIDELEKHYPELACEMKIIKTKGDLIQDKPLDKIGDKGIFT
KEIEAELLKGNIDMAVHSMKDMPSELPLGLRFTRTLKREDARDVLILKEGYASIEDLPIG
ATIATGSKRRKYQLLAYRSDLNIVPIRGNVDTRLCKLEEEKLEGIVLAAAGLHRLGLADK
ITCYLPMEIMLPAPAQGALAIEIRQEDTKAYDLVKVLEDPVSSIQVEAERAFMDAINGGC
HMPIGAYCEVIGTKLRMRGLLGDELGKKLVIKELCAPIGSEKQLGEELASVLRKEFEKND
W
>B5UN31|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus AH1134|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDDE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAITERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEEVGLEAADRLIKQGAKEL
ILAANKEQQ
>G4KJ75|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia enterocolitica subsp. palearctica PhRBD_Ye1|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPIAFPEGLGLVTICERDDPRDAFVSINYAHLDELP
AGSIVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDKGEYHAIILAVAGLKRLGLE
TRIRYAMPAEESLPAVGQGAVGIECRLDDNFTRQLLAPLNHRETELRVCAERAMNTRLEG
GCQVPIGSYAELDGDTLWLRALVGAPDGSEIIRGERRGPAENAEQMGVELADELLSRGAR
EILAEVYQDNPPL
>G4QF18|hydroxymethylbilane synthase|EC 2.5.1.61|Glaciecola nitratireducens (strain JCM 12485 / KCTC 12276 / FR1064)|TrEMBL
MSTTKPAQRVIRIATRKSDLAMWQAKYVQAELLKHHPDLSVELLPMSTQGDRILDTPLAK
IGGKGLFIKELEIAMQNGEADIAVHSMKDIPVAFPDGFGLHAICERENPFDAFVSNSFES
IEALPQGAVVGTSSLRRQCQLRAFRDDLVIKDLRGNVNTRLAKLDAGQYDAIILAAAGLI
RLGMRDRIKQEVSADLSLPAVGQGAVGIECRNDDAELIELVAALNHTATATRVKAERAMN
AKLEGGCQVPIGSYAVINGNLLLLRGLVGTPDGKTMLKSQVEGPLIDAEKIGQAVANELL
TKGAREILDSLGND
>F0HZK4|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK72|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKELHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCVLGAISQREDVRDCLIFRQAGQTLANLPQ
GALIGTSSIRRQVQLQAQRPDLTFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWMD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRQLLATVQDEKTAAEVSVERAVLAQM
NADCSFPIAALARKNDQDYQLEAMLAKEDGQCIFVSLQGQDGQELAEQAVRQLADKGAVG
MPWLKK
>I6HK39|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis PY-12|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>I5HDB5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA10|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C9D046|hydroxymethylbilane synthase|EC 2.5.1.61|Silicibacter sp. TrichCH4B|TrEMBL
MTLTLPSPASPLKIGTRGSPLALAQAYETRDRLARAFELEPTAFDIVVIKTTGDNRAMID
ADRPLKEIGNKGLFTKEIEEALTSGGIDLAVHSMKDMPTEQPEGLMLDCYLPREDVRDAF
VSPQIRAIADLPEGAVVGTSSLRRRAQLLHRRPDLQVVEFRGNVQTRLQKLQDGVASATF
LAMAGLRRLNMAEEVPATPIAPEDMLPAVAQGAIGIERRSDDTTAAAMLEAIHHAETSLR
LAAERAFLAALDGSCETPIAALADLSGGTLQLRGQILRPDGSEALADQQSCAIEDGAELG
RRMGEALRARAGEGFFSH
>E7XYS0|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. OH_2009072675|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>C5TAS0|hydroxymethylbilane synthase|EC 2.5.1.61|Acidovorax delafieldii 2AN|TrEMBL
MSPTSLPPLVIATRESRLALWQAEHVQALLRARGHTVSLLGMTTQGDQILDRSLSKVGGK
GLFVKELEVALEEGRAHIAVHSLKDVPMELPEGFALACVMEREDPRDAFVSPRYASLEAL
PQGAVVGTSSLRRQVLLQALRPDLRIEPLRGNLDTRLRKLDEGQYDAIVLAAAGLKRLGL
QERIRTEFATTAMLPAAGQGALGIEIRSDRQDLIEALAPLAHQETWLTVTAERAVSRAMG
GSCS
>E6PSM7|hydroxymethylbilane synthase|EC 2.5.1.61|mine drainage metagenome|TrEMBL
MHSATLPAQLSPVPARLVIATRESRLALWQAEHVQALLRGLHPGCAVALSGMTTRGDQIL
DKTLSKVGGKGLFVKELETAMEAGEADLAVHSLKDVPMVLPEGFALPVIMQREDPRDAWV
SSKAAHFTALPQGAVVGTSSLRREMQIRALRPDLKVVPLRGNLDTRLRKLDEGQYDGIVL
AAAGLKRLGLESRIRALIDTTEMLPAVGQAALGIEIRADRADVAAALGPLDHVPTHLCAA
AERAVARALGGSCSTPLGAHATWSGSTLQLRALLGLPDGSRMLRADIAAEVSTLQAAEAL
GREAALALQAQGAQAMLEQLQAV
>F3BL86|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas haloplanktis ANT/505|TrEMBL
MTEKTKLVRIATRKSALALWQAEFVKAELERFHADVRVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLDGRADIAVHSMKDVPVEFPQGLALHTICEREDPRDAFVSNNFANLSA
LPQGAIVGTSSLRRQCQIKALRPDLDIRDLRGNVNTRLGKLDDGQYDAIILAAAGLIRLE
MESRIADYIEPEVSLPANGQGAVGIECRIDDEVTKALLAPLEHTQTRIRVNAERSMNRYL
EGGCQVPIGAYALVDGEQVHLRGLVGAVDGSEILRDEVTGHVNDAEKIGIELAKKLLAQG
ADKILAEVYRDA
>Q3RFM2|hydroxymethylbilane synthase|EC 2.5.1.61|Xylella fastidiosa Dixon|TrEMBL
MPLLRIATRKSLLAMRQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIG
ARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQR
MTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRQCVVAERTMNRALHGSC
HVPVGAYASYGVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAEL
LAATA
>D3D314|hydroxymethylbilane synthase|EC 2.5.1.61|Frankia sp. EUN1f|TrEMBL
MTDTREPDARSHARSFAWLTRRPLRLGTRRSALALAQSGHVAEALRARLGCQVELVPIVT
DGDRSQGAISQIGGTGVFVSALREALLSGEIDLAVHSLKDLPTATPDGLVLAAVPPRVDT
RDVLVSPSGRGLVKLGPNARIGTGAPRRAAQLRAMGLGFDVVPIRGNVDTRIKKAIDGEV
DAVILAHAGLARLDRLDAVTEIIPSEVILPAPGQGALAIECVRTAGTAVAPLAGSALTGG
GSAGGRPAGGGSAGGGSAGGGLAESGQSYVRSGPDLSQAIDGGLAELLRFVLDDAPSSVA
VRAERAFLAGIEAGCTAPVGALGRVLPSTGSSPTTGGDGAPAVGDLRLRAVVAAPDGSRV
LRCELTGSAVDPEALGQRLADEMLSAGAQTLMGTS
>D3D314|hydroxymethylbilane synthase|EC 2.5.1.61|Frankia sp. EUN1f|TrEMBL
MTDTREPDARSHARSFAWLTRRPLRLGTRRSALALAQSGHVAEALRARLGCQVELVPIVT
DGDRSQGAISQIGGTGVFVSALREALLSGEIDLAVHSLKDLPTATPDGLVLAAVPPRVDT
RDVLVSPSGRGLVKLGPNARIGTGAPRRAAQLRAMGLGFDVVPIRGNVDTRIKKAIDGEV
DAVILAHAGLARLDRLDAVTEIIPSEVILPAPGQGALAIECVRTAGTAVAPLAGSALTGG
GSAGGRPAGGGSAGGGSAGGGLAESGQSYVRSGPDLSQAIDGGLAELLRFVLDDAPSSVA
VRAERAFLAGIEAGCTAPVGALGRVLPSTGSSPTTGGDGAPAVGDLRLRAVVAAPDGSRV
LRCELTGSAVDPEALGQRLADEMLSAGAQTLMGTS
>F9EMK5|hydroxymethylbilane synthase|EC 2.5.1.61|Fusobacterium nucleatum subsp. animalis ATCC 51191|TrEMBL
KNIIIGSRGSILALAQANLIKDKLQINYPNLIFTIKEIVTSGDKDLKSNWENSDVSLKSF
FTKEIEQELLDGDIDIAVHSMKDMPAISPKGLICGAIPNREDSRDVLVSKNGFLVTLPQG
AKIGTSSLRRAMNLKAVRPDFEIKHLRGNIHTRLKKLETENYDAIVLAAAGLKRTGMVDK
ITEYLSGEVFPPAPAQGILYIQCRENDEEIKEILKSIHNENVAKIVEIEREFSKIFDGGC
HTPMGCYSQINGDKIKFTAVYSDEGKQIRAIIEDDLAKGKEIAYMAAEEIKNKINKGTIQ
>H4DBF9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIGC340D|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E8I1X0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H- str. H 2687|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q1MZM5|hydroxymethylbilane synthase|EC 2.5.1.61|Bermanella marisrubri|TrEMBL
MTVLKIATRSSKLALWQAEFVKSELEKFHSDLQVELVKIKTQGDKILDTPLAKIGGKGLF
VKELETAMLNGDADIAVHSMKDVPMEFPEGLGLSVICEREMPTDAFVSNHYQRFLDLPQG
AHVGTSSLRRQCQVLAARPDLKVSSLRGNVQTRLGKLDAGEFDAIILASAGLLRLELEER
VAEHMSDEISLPAGGQGAVGIECRMDDEVTQKLLAPLHHSDTASRVYAERALNKRLQGGC
QVPIACYATLNDGELHLRGLVGSEDGSRIIRTEIRGPESQAEQLGIQAAEDLLAQGAGEI
LSEVYGFDVK
>A5GJC0|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain WH7803)|TrEMBL
MSMALEHLRIASRRSQLAMVQTNWVKAELEKAHPGLAISVEAMATQGDKILDVALAKIGD
KGLFTKELEAQMLVGRAEIAVHSLKDLPTNLPEGLMLGCITEREDPADALVVNSKNAEHT
LETLPEGSVVGTSSLRRLAQLRHHFPHLQFKDVRGNVITRLEKLDAGQYDCLILAAAGLS
RLGFGDRIHQIIPGHISLHAVGQGALGIECVCDRPEVLKIIQVLEHAPTAGRCLAERAFL
RELEGGCQVPIGVNSRIDGTELILTGMVASLDGQRLIRDERRGSLTDPEAIGRALAADLK
SRGAGEILQEIFAEMRPEA
>G8LU06|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium clariflavum (strain DSM 19732 / NBRC 101661 / EBR45)|TrEMBL
MKIIRVGSRDSKLAIIQAKLVMDAIERYDKNIKTELITMKTTGDKILNKSLDKIGGKGLF
VKELDNALLNDKVDITVHSYKDIPMEINPDLPIVAVSEREDERDVLILPKGKIDKTKPIG
CSSKRRTIQLLQLGYENIAPVRGNVISRLNKLDEGQFSALVLAAAGIKRLGLEERIYRYF
STEEIMPAACQGIIAVQARKGENVDFLKGFHCEKSKYIADAERAFVAALEGGCSSPVAAH
AQIQGDKLILNGLYVDEKMGILKKGSMSGSVEDAQNIGKSLARKLKEEVWKWGRGL
>A3JRA2|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacteraceae bacterium HTCC2150|TrEMBL
MKKFTPQSPLKIGTRGSPLALAQAHETRDRLSKAHNLAPEAFEIVVIKTTGDIVQDRPLK
EIGGKGLFTKEIEEAMLSGDIDIAVHSMKDMPVEQPDGLAITCYLPREDVRDAFVSLSAD
SFDDLRQGATVGSSSLRRRAQLAHRRPDLNLVEFRGNVQTRMRKLGDGVADATFLAMAGL
IRLGMSDVARLPLETDVFLPAVAQGAIGIEQRIGDSVISEMLTAIHDQHTGDLLAAERAF
LARVEGSCQTPIAGLAEIIDGKLHFRAEILRPDGSEAITGAASGEIADGAAIGRQVADDL
LARAPTGFFEWMK
>H4MZ12|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC3C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A0YIV0|hydroxymethylbilane synthase|EC 2.5.1.61|Lyngbya sp. (strain PCC 8106)|TrEMBL
MLGEELEKILLSFFLIPHFSLLILIKQFTPKALMQKALMQKVLMQK
>H3KW98|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC2B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D2P5C2|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 1/2a (strain 08-5923)|TrEMBL
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEAIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNQVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPEVCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEFVQFKGLVGNADGSIILESEQVGANPSEIGNKVAEDLLSEGAD
TIIKELRNV
>D3EQA4|hydroxymethylbilane synthase|EC 2.5.1.61|cyanobacterium UCYN-A|TrEMBL
MVVSNRLIRIGSRKSQLALVQTYWIQEQLQKHYPNYEFQIETMSTQGDNILDVALAKIGD
KGLFTKELEVAMLQNRIDFAVHSLKDLPTNLPEGLMLGCITERENPADALVVNEKYKNNK
LDTLPEGSIIGTSSLRRLAQLRHHYPYLIFKDVRGNVNTRLAKLDAGEYDAIILAAAGLK
RLNMDNRIHQIIPEDISLHAVGQGALGIECRAADSRILELLEVLKHSETHYRCMGERSFL
RALEGGCQVPIGVTTKIECNILTLTGIVASLDGKTMLKNTVSGHMEQAENLGYELSVCLR
DAGATEILDKIFSETRIQ
>G2A6K8|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli STEC_94C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F2ZQ05|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. oryzae str. 1_6|TrEMBL
MSTREIRIATRQSALALWQAEYVKSRLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDRADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFDSLQALP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVEDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAILEGDDVWLRGLVGDPSGSVLLHAEARAPQTSAQALGVEVAEALLAQGAA
KILKAVYGEANNE
>H4IZJ5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC1C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C5ZB50|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei 1106b|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>E7WWG9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 515920-2|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>F6BSK5|hydroxymethylbilane synthase|EC 2.5.1.61|Sinorhizobium meliloti (strain BL225C)|TrEMBL
MQTKPFRIGTRGSPLAMAQTHETRDRLAAAHGLPPEMFEIVILSTKGDRITDRSLAEIGG
KGLFTEELEQQLLSGDLDFAVHSSKDMPTKLPEGLFLSAFLPREDIRDAFVGRSAKRLVD
LPQGATVGSSSLRRQALIRRLRPDIDVITYRGQVETRLRKLAEGQVDGTLLAYAGLRRLG
MEHVPTELLDPEEFPPAPAQGAICVEARIGDDRINTLLAAIDDPRTHEAVSCERGFLATL
DGSCRTPIAGYAQSDGTHIRFAGMILTPDGTTSHQIEIDGRAADAERLGQEAGERIRAKA
GPGFFSSWS
>B3PQA5|hydroxymethylbilane synthase|EC 2.5.1.61|Rhizobium etli (strain CIAT 652)|TrEMBL
MQTKPFRIGTRGSPLALAQAHEARDRLMAAHHLPEEMFEIVVLSTKGDRITDRSLAEIGG
KGLFTEELEQKLVSGELDFAVHSAKDMPTHLPDGLHLSAYLPREDIRDAVIGRTAPKLID
LPHGATVGSSSLRRQALIRRMRPDINVIIFRGSVETRLRKLEEGQVDATLLALAGLKRLG
KVEVLTDILDPDTFPPAPAQGAICIESRIGDSRIDDLLAAVNDAATFDTVSCERAFLAAL
DGSCRTPIGGYAVCEGDLIRFSGLIITPDGRSQHAVTTDGHRRDAAALGTRAGQDVRARA
GSAFFDDWH
>I2TR13|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 3.2608|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>H0JF83|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas psychrotolerans L19|TrEMBL
MLREIRIATRQSALALWQADYVKARLEAAHPGLRVTLLPMTSRGDKLLDAPLAKIGGKGL
FVKELENALLDGSADIAVHSMKDVPMEFPAGLGLYAICEREDPRDAFVSNRYQGLAELPQ
GSVVGTSSLRRQAQLLALRPDLEIRFLRGNVNTRLAKLDADDYDAIILAAAGLIRLGFAE
RIREYLTVEDSLPAGGQGAVGIECRTDDAEVHTLLEPLHHFDTERRVAAERALNRRLNGG
CQVPIACYAVQEGELLWLRGLVGQPDGGLLLRAEARGPLNDPAGLGVTVAEDLLAQGAQG
ILDAVYGASGAS
>I4BBV2|hydroxymethylbilane synthase|EC 2.5.1.61|Turneriella parva DSM 21527|TrEMBL
MALLAGETFTLASRDSLLALAQSIEAALLLQSHGAEVKILTLKTSGDIKLDAPLYDVAAA
AAPKEGRAFFTRELDDALQNGKADIAVHSFKDLPTEPVAGVSDPIFFSEQTGADILVTLK
HAAQARQIIGTSSLRRIHQLQHALPEATTVTLRGNIVTRLRKLRQGEAGMNAILIAGAGI
FRVRNFAKLAPEAYANLLESSIAEKVARELGEFTEYLDDGVTIQELDEAVFPTAPGQGVL
ALQMSAACEQTLGQKLRALFESHAHIAKRVGLERQLMTALGTGCHAPLGVSALRAGNGLQ
VTVCYSRKSQTSPPAFFDSVFLRRNTREDAGPLVAEAKHGFERFFWWGLSEPPAAHSEKW
TFVRALKQNLLHPHFDETAQYGHIFVSSKTAADWLKASPIRGKVNLWAAGEETAKYVALA
FAGSRVESCAEKGFGAAYSRMRGENKERVLWLGSASGLGRAQAIAAIDSEIDFLCVYENL
PAEPETLAADYTALGQAVAQNTALHCLTSRASAEAFIRFAKLASAPTANISCFGKSAAEC
VETAGYRIYHKSNAASFTEYLREIEGDTALMRIEEENTK
>D6YKJ3|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar G (strain G/11074)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>H2HV63|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain HC04)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>B6BVM5|hydroxymethylbilane synthase|EC 2.5.1.61|beta proteobacterium KB13|TrEMBL
MWQANYIADRIREKYPDTEVNVLSFKTQGDIILDQPLAEIGGKGLFIKELEHALLNDDAD
LAVHSMKDVPMDLPEPFEICAISERENPSDAFISNKYASLDDLPQDAVIGTSSLRRQSLI
KHTRPDLIIESLRGNLQTRLKKLDSGIYDAIILASAGLIRLNLENRIKSTLDVKQYIPSV
GQGALGIEILKNKSEVKEFLDFLNDEQTQIQVEAERKISKTLAGSCTVPMGAHASIKNNL
LTIQAFVSSPDGIKMIRATDTGPCSEHLSLANNVAQSLIDQGAKNILGLEHG
>A8CBG6|hydroxymethylbilane synthase|EC 2.5.1.61|Toxoplasma gondii|TrEMBL
MTLLREQRSAGAALRLSWVAFLFGFLVLLRDSLFKESYETPAVLLFAAARLLAPPLTPRA
GQGGASSASSSSRLSPSARFPAASWSSSAALVSLLSPPASSRASPSRRNADVPSPSFAVT
ARPLARSSRESRLSPLAFLPVSASQNAVQTTPPFSGASEKTPLRVGSRASPLALAQARQF
VYRLALRFPDAFPQAHEIIQASLAKLSNPLPSSSSSDSSSSSSASPSSSSSASSSSSSSP
ANSHLASSAFSSVLASLLRVDSRLEYGELRIVPMQTTGDKELHLPLAQVGGKGLFTKELD
LALLHGQVDVVVHSLKDVPTELPEGTEIGAYLPREDPRDALIFSRKPRRGLSRACKAQVP
GGVAETARRSATQQRVSAAASGAPSVGSSASASLLPYLPDALFASGGLPEETEEAGRAAR
ASHTEDDAGGVEGEARKGDEGRPRIGTCSLRRQALLYALLPPSSFQLMGLRGNVQTRMSR
IEKGTLDATLLAAAGLKRLNLLSAMLAPSPSATPSPCPAPSPNETSRGTEPGGCVEAVLL
PADVFVPAVCQGIIGVQCRSADTGILSLLRELNSPSSRGQALCERAFLRALDGSCRTPIA
GIAEWRAVPAQGEAPRPQSQNGSDEPGVEREGEEGCAGSSVKGREGRSEEGWGGHPDCFT
EKTELRFCGVLATPDGKQLLRFCGVLATPDGKQLFREERTVRGVRTPEEAEALGRAVAEE
IKKAAGADRLAQIKKHVTEGWKNLKTL
>D0HVE8|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae CT 5369-93|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>I5XXJ0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC1738|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>G3IQZ3|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacter tundripaludum SV96|TrEMBL
MNGVLLTEKIIRIATRRSPLALWQAEHVAERLERTFPGCRTELVKMTTQGDKILDAPLAK
IGGKGLFVKELEQGMLEGLADIAVHSMKDVPVEFPEGLHLAAILIREDPTDAFVSNHYAT
LHDLPANARIGTSSLRRQCQIKELYPEAEILSLRGNVNTRLSKLDSGEYDAIILASAGLK
RLGMAERITQCLDTSVSLPAIGQGAIGIECRIALLVAGAGAFYIADYASWKVAYFVMATA
MSVGLVTTLCLKEPDHKHFDGRLSEDVAVKRQNIWRRLSISFVDAVLHPFVEFFGRNGKV
GLLILMLIAVYKMSDITMGVMANPFYLDLGFSKKDIADISKVFGFFMTIAGAAMGGVLVV
RYGIMRSLLLGAVMVAATNLLFAVLAVSDPNLLLLAGVISADNLSGGIATSVFIAYLSGL
TSTAHTATQYALFSSLMTLPAQLLGGFSGVVVDSYGYTVFFIYASTVGLPAIVLVLLLMR
YQSRSKAYNYNP
>D4XA02|hydroxymethylbilane synthase|EC 2.5.1.61|Achromobacter piechaudii ATCC 43553|TrEMBL
MSLPQRLVIATRASRLALWQAEHVRDRLRTLYPACAVELLTLTTRGDQILDRTLSKVGGK
GLFVKELENALLDGRADLAVHSLKDVPVDLQAPFELCAILDRADPRDAFVSNRYAGLADL
PAGAVVGTSSLRRESQIRARFPTLVVKPLRGNLDTRLGKLDKGEYDAIVLAAAGLQRLGL
ESRIRSLLDPADSLPAAGQGALGIEIRNDRDDMRAWLAPLISAATTSCVQAERAVSRKLG
GSCQVPLAAFAEISGDTLSLRALVASPDGVRMVHTRRSGPVADAQALGEAAAQELLDAGA
AAILQELLQADPRPD
>C3NUA0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae serotype O1 (strain MJ-1236)|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>G6F0X2|hydroxymethylbilane synthase|EC 2.5.1.61|Commensalibacter intestini A911|TrEMBL
MSTDTLLHISSNSALQEVAKKAAHKGLQDHHDAYQRRGLPLRVGTRGSPLALVQTRNFLT
RLTQFCPLLRELGAFQEFQISTSGDKIQDRRLAEIGGKGLFSKEIHEQLSAGNIDFAVHS
LKDLETTLPDGLVLACTLKRQDARDALIVNSKYRPVDADYPFDCLPQGAKIGTSSVRRQA
QLLHIRPDLEIALLRGNVQSRLDQVTANKYDATFLAAAGLQRLGMEDRIDVLLDPSIMVP
AAGQGIVGVTVREADVELREMLAAIEDQEAKAVATAERALLAELDGSCRTPIGGYAQLLP
VVAGGAPELHLVGLVAREDGSFLLKKEISGSAEDAEALGHELGQQLRKDSPADIFNE
>C0Q9U2|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2)|TrEMBL
MQWMYCNQLLLMHQRIGPMKKTIKIGTRGSKLALWQANHVKDRIEDQFPETEVEIMTIKT
TGDMIVDRPLSMVGGKGLFVKEIEKALLESTIDMAVHSMKDMPGELPPGLVIGAVPAREN
PFDVLISNNNLSLADLPKGARIGTSSLRRASQIKHARPDIETASIRGNLDTRLKKLAAGE
FDATLLAAAGLIRLGMKTVITQYFDETIMIPAVGQGALCIESRQEDLDIAPVLAFLNHGE
THTVVSGERAFLRRLDGSCHIPVACFGRLEDHRVILTGLVASEDGRTILKETVAGTPEDP
QKAGIALAETLLSKGADKILENLNS
>H4K9Y1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC2A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>G2Z3B7|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacterium branchiophilum (strain FL-15)|TrEMBL
MLPSGARGPIRIGTRDSELALWQAKTVEKQLNDLGYKTEIIAVKSEGDIVLDKPLYELGI
TGIFTKTLDIAMISGQVDIAVHSMKDVPTSLPNGIVQAAVLERASVFDILVYKDNLDFLS
QENSTIASSSLRRKASWLHKYPTHTIEDIRGNVNTRMQKVAESNTWSGAIFAEAGLERIN
LKPEKAIVLDWMIPAPAQGAMVVVCNAEDFFSFDAVSQLNHIETEICTHIERQFLKTLEG
GCTAPIGALAKYDEDKDTIEFHGVLFSVDGKQKFEIEKSVDISEWKKLGFHAAQEILNNG
GAELMMEIKTQLKK
>H8NEV3|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia prowazekii str. RpGvF24|TrEMBL
MINSIRIGTRNSTLALIQTNLVIEQIKQIFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGKIPVELVIAAVLEREDPRDVLVCLNYQSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDAIILSYAGLKRLNVFN
QKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPERAFLEYLDA
NCSTPIAAYAQYLDAYNIQIDFMLGNLDCTKIIFQTEITNIKTSKICGIKAAKMMLAQQ
>E8P6D0|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis bv. Medievalis (strain Harbin 35)|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>E6RVT0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni (strain S3)|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>D7HTC6|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas savastanoi pv. savastanoi NCPPB 3335|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDELP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
NRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPAGSVLLHAEARAPQTSAQALGVQVAEALLAQGAA
DILKAVYGEANNE
>F0APE3|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis ES14902|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLQADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>Q1BUI9|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia cenocepacia (strain AU 1054)|TrEMBL
MGFLGKARVKRNCGNCGNCGQATSYVRHIRTTAPRPARKQAGRRLRARAGRGVRATIVRS
SIPSFDVPAMNSETPAAGPQQAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKI
LGMTTRGDQILDRTLSKVGGKGLFVKELEAALADGRADLAVHSLKDVPMALPDGFSLAAI
MEREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRSRYPHLEVLPLRGNLDTRLAK
LDRGDYAAIILAAAGLKRLGLEARIRALLDVEASPPAAGQGALGIEIAAHRDDVAAWLAP
LHDPQTALAVEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGKRVLTAEECG
AVVTVADALALGRAVSDELEAQGALDIVQALLASSQAAGKGDA
>A9CUB8|hydroxymethylbilane synthase|EC 2.5.1.61|Hoeflea phototrophica DFL-43|TrEMBL
MDVSQMKPYRIGTRGSPLALAQAHETRERLMAAHDLPESAFEIVVLSTKGDRITDRPLAE
IGGKGLFTEELEEQLSDGRLDLAVHSSKDMPTALPEGLGIVTYLEREDPRDAYISSAAPR
LEDLPQKAVVGSSSLRRQALIRRLRPDISVITFRGLVDTRLRKLADGEVHATMLAFAGLK
RLGKSEVVTNLMDPESFPPAPGQGAICIEARLDDERIAELLAPIDHADTHAALNCERGFL
GALDGSCRTPIAGHATLENGQVSFYGMILTPDGTTFHDIRVQGPAADAAQLGADAGAEVR
ARAGSKFFESWS
>H5GJ98|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC11A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H8KJV1|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia rhipicephali (strain 3-7-female6-CWPP)|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEAFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLKICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDADPRHLSKLAYRDREAFEGNTEALATAAYKSDRTDASTELTYKFPL
EVEFGKMSNIQTDFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>B5P8G9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Heidelberg str. SL486|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKY
HSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAG
LKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEE
LLENGARAILTEVYNGETPA
>F9JDC8|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii ABNIH4|TrEMBL
MLEFMKTLKIATRQSPLALWQAEHIRARLQELHPDLTVELVKFVTQGDKILDTPLAKIGG
KGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQFEKFAD
LPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAGLKRLG
LAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLTLIQPLLHPETDVCVRAERAFNAYL
EGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARNLLDQG
AGDLLKALY
>H2HN50|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain HC03)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>H7S1S8|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 2692|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>B5NVT9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Kentucky str. CDC 191|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDVLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>D7GFS7|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / CIP 103027 / CIRM-BIA1)|TrEMBL
MSQTPQGASGDRRVLKIGTRGSRLARSQSAMTAALIEQVTGLPTELVIVHTDGDDLSIPL
SAPPRPGAFVARLRDVLLDGEVDIAVHSFKDLPFAPMPGLSVVAVPQRAAALDALVSRDA
LGLDELPAGSKVGTSSPRRASALLRYRDDLEIVPIRGNVDTRIRKVREGRVDAAVLAAAG
LERLGLHDEITELIDPKVIVPAPAQGALAVEMRTDDPLAATVAQINDHDTRIQVAAERQV
LTGVQATCTTAIGAHSVLQGYSLTLMADLTDHMGVAHAHVARTIGLRRGDPTDDARALGE
SVAEQLLERP
>A8LIJ6|hydroxymethylbilane synthase|EC 2.5.1.61|Dinoroseobacter shibae (strain DFL 12)|TrEMBL
MGILRSRRDVSLMAQNGLSSQVDTYRDATMTITLPTPDSPLKIGTRGSLLALAQAHETRA
RLSAAFDLPEEAFEIVVIKTTGDRIQDRSLSEIGGKGLFTREIEDAMLDGSIDIAVHSMK
DMPVDTPAGLALDTYLPREDVRDAFVTLDGGTLADLPEGAVVGSSSLRRRAQLAHRRPDL
QLVEFRGNVQTRMKKLGDGVAHATFLAMAGLNRLGMDEVPRSAIAPEDMLPAVAQGCIGI
ERRADDPRAAEMLAAIHDGPSGHRLACERAYLSALDGSCQTPIAGLAELDGGSIHLRAEI
LRPDGSEVLSDSETAPVEDAAKMGREVAERLRARAPDGFFSWLTAHA
>A9WPH6|hydroxymethylbilane synthase|EC 2.5.1.61|Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235)|TrEMBL
MARTQSQLIADQLSAIGGFEVELVQIRTDGDVLTGPLSQMGGTGVFVTALREAVLNGSVD
FAVHSLKDLPTAAAPGMKIAAIPARAEVRDALCSRSNRSLAELATGAKVGTGSPRRAAQL
RAARADIEVIDIRGNVDTRLARLENDLDAVVLAAAGLGRIGRSAAISELFDDAVMLPAPG
QGALAVETALDVPTELAAALAAIDDADSRLAVTAERALLARLEAGCSAPVGAFAQRKGSM
LRLEACICSLDGSRVIRQAKATDGLAEVAATLLGIELAESMLADGAADLL
>C6RTZ7|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae CIRS101|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>A9W9H7|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacterium extorquens (strain PA1)|TrEMBL
MSLSRALRIGTRGSPMALAQTGMVRDRIVAANPGLETEIVVVSTVADRVLDRPLSEIGGK
GLFTKELEQALFADEIDVAVHSMKDVETWLPDGLAIACILERDDPRDAFLSANGANGLAD
LPPGARVGTSSLRRGAQVLMHRPDLTIVPLRGNANTRMRKLEAGECDATLLALAGLQRLG
MADVARSVLSVEEMLPAVAQGALGIECRAGDDAIRALLAPVACATTTTALDAERGLLAEL
DGSCRTPIAALAQVKGDRISLDGLLFLPDGSRHWAVHREGLAADADTIGRDAGAELKRAA
GDVYFAHLK
>H7ZK35|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 2008-894|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>D5CFU6|hydroxymethylbilane synthase|EC 2.5.1.61|Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKQRLEACHSGLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELELALLENRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNQFDSLDALP
KGSVVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRVALPPELSLPAVGQGAVGIECRLDDRRTRELLAPLNHDETAIRVKAERAMNTRLEG
GCQVPIGSYAELINGELWLRALVGAPDGSQMVRGERRGKPQDAEQLGISLAEELLDNGAR
EILAVVYDGEPPA
>C9P0R6|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio metschnikovii CIP 69.14|TrEMBL
MTSTPPIRIATRQSPLALWQAHFVKDALQAAHPHLAVELVTMVTRGDVLLDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYHSLEAL
PHGAIVGTCSLRRQCQIKAARPDIIIKELRGNVGTRLAKLDAGEFDAIVLAAAGLKRLKL
EQRIASFISPEQSLPAVGQGAVGIECRLDDQRLLTLLEPLNHADTYDRVICERAMNLTLQ
GGCQVPIGSYTELDGEQIWLRALVGEPDGSRIIRGEIRGPRQQAERLGVELAQQLLDQGA
RDILNKLYADHE
>F3RK59|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes J1-220|TrEMBL
MINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGLFVSEVEQALSDEVIDFAVHSM
KDVPSSLKEGLIIGAIPKRESPLDCFVFNRVNSLDELPQGSVIGTSSLRRAAQLLKHRPD
FVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLENTTLKLEDIPPELCLPAVGQG
ALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKLNGGCEIPIAGFATRANEVVHF
KGLVGNADGSIILASEQAGANPSEIGNKVAEDLLSEGADTIIKELRNI
>D8PGR3|hydroxymethylbilane synthase|EC 2.5.1.61|Candidatus Nitrospira defluvii|TrEMBL
MNRSTLILGTRGSKLAVHQSQWVQARLQELAPGLTISLQRIQTSGDKILDVPLAKIGGKG
LFVKEIEDALLSKEIDLAVHSMKDVPTALPEGLDILCVPPREDPRDALITRDGCRLDQLK
PGAKIGTSSLRRQAQLLHYRPDFTIEMLRGNLDTRLRKLREGQFDAIVLAAAGLRRLAWD
AEITEYLPVHLSLPAIAQGALGIEARSDDTFVRELLSRFEHRPTRITVTAERALLHRLEG
GCQVPIAAHAALEGDRLTVDGLVASVDGRRVIRHQIQGPASEAQALGTKLAERLLADGGD
VILKEIYGQA
>D8PGR3|hydroxymethylbilane synthase|EC 2.5.1.61|Candidatus Nitrospira defluvii|TrEMBL
MNRSTLILGTRGSKLAVHQSQWVQARLQELAPGLTISLQRIQTSGDKILDVPLAKIGGKG
LFVKEIEDALLSKEIDLAVHSMKDVPTALPEGLDILCVPPREDPRDALITRDGCRLDQLK
PGAKIGTSSLRRQAQLLHYRPDFTIEMLRGNLDTRLRKLREGQFDAIVLAAAGLRRLAWD
AEITEYLPVHLSLPAIAQGALGIEARSDDTFVRELLSRFEHRPTRITVTAERALLHRLEG
GCQVPIAAHAALEGDRLTVDGLVASVDGRRVIRHQIQGPASEAQALGTKLAERLLADGGD
VILKEIYGQA
>Q329Y0|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella dysenteriae serotype 1 (strain Sd197)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLVALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>I4U3D3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 541-1|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I5BBX2|hydroxymethylbilane synthase|EC 2.5.1.61|Sphingobium indicum B90A|TrEMBL
MTVAALRARHGWDEGAVEIVVVQTSGDRIQDRALADIGGKALWTKELDRALASGEIDFAV
HSMKDVETIRPAEIRIAAMLPRADVRDRLVGADGFAALPERPVVGTSSPRRAAQVRRLRP
DAQVVLFRGNVATRLARLDRGEAHATLLAAAGLDRLGQGDVGVAIPVDVMLPAPSQGAVG
IETLSGDEAMLDLLAAISDADTFDCVMAERAVLAGLGGTCHSPIAAFARLEDGQVRLRAE
IISPDGQETVGETARIERGDAAAAEAMGRGLLDRASPALRLLFEA
>H8A5I2|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 2008-979|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNAHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>G8S657|hydroxymethylbilane synthase|EC 2.5.1.61|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MTSVKPLRLGTRGSKLALTQSQMVADELTLATGRAVELVRIVTPGDTSSAPVAQLGVGVF
VSALRDALVAGEIDFAVHSYKDLPTAEHPRLTIPAIPRREDPHDVLVARDGRGLADLPPG
SLVGTGAVRRIAQLRALGLELQVTPIRGNIDTRIARVLGPDADLDAVILARAGIARIGRT
ADITQTLDPMLMLPAPAQGALAVECRSGDADLVELLATLDHAPTRAAVVAERALLATLEA
GCAAPVAAYARLVRGRHAGSAPEDGRGEEMIHLRGAVISPDGVRAIRLSRTGTPAGAAEI
GKALAADLLDAGADTLMGSTE
>E1JXL6|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio fructosovorans JJ|TrEMBL
MRDKLVIATRGSKLALWQANHVAARLKEAHPGLAVDLLPIKTKGDRILDVPLAKVGGKGL
FVKEIEEALLDGRADLAVHSMKDVPAEQPAGLVVGITPKREDPCDMLLSVAYDGLDALPE
GAKVGTSSLRRKAQLTALRPDLAIVDLRGNLDTRVGKLTDGLFDAIVVARAGLNRLGLSA
PKSERLCPPRFLPAAAQGALGIEYRFDDRETAAMLAFFDHPESRDAVAAERAFLGRLEGG
CQVPIAAHAVIDGNLISIDGLVADPDTGRTFRDVATGKRDDAVELGKKLADSVLAMGARA
ILDAVYKNVP
>F2GT72|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella melitensis (strain M5-90)|TrEMBL
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDVLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>F9B6N1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HFU-02|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>C7BY25|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain B38)|TrEMBL
MEKLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLNIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDGVKIQAVLGLPNGKEVITKEKRGDKTKAFDLIQELLEEFLQSGAKEIL
EKAQLF
>H7EWQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas stutzeri ATCC 14405 = CCUG 16156|TrEMBL
MSREIRIATRKSALALWQAEYVKARLEASHPGLKVSLVPMVSRGDKLLDAPLAKIGGKGL
FVKELETALMESDADIAVHSMKDVPMEFPEGLGLYCICEREDPRDAFVSNHFDDLDALPP
GSVVGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFGE
RIRSSIGVDESLPAGGQGAVGIECRTTDSELHALLECLNHAPTATRVVAERALNKRLNGG
CQVPIACYAVLEGEQLWLRGLVGQPDGTVLLRAEGRAPATEAETLGVQVAEALLDQGAEQ
ILQAVYGEAGHE
>H0TTI9|hydroxymethylbilane synthase|EC 2.5.1.61|Bradyrhizobium sp. STM 3843|TrEMBL
MTRFRIGTRKSTMALAQTEEIARRLTAAIPSLDVEIVKFETTGDADQTSKLLTHGGKGGA
FVAEIRRAMLAGQLHAAMHSLKDMPGNEETPGLVVAALLSRDPPGDVLVLRQGLSLEDFR
CDGGTGFKIGTNAVRRAAYARRLFPNAQVIHFRGAADTRIRKLDHRELQRLPDGGAVGPA
DALIMARSGLERVGLADRASYEFPVADMLPAVGQGIVAVECVGTDWETRRILSTIDDPAA
RACADAEREVLWVLNGHCNSPIAGFATIDGAQMTLTASVLDEAGDRFIEAQRTGPADRPR
ELGRAIGLELLANGAAELIERSRPR
>Q5NL83|hydroxymethylbilane synthase|EC 2.5.1.61|Zymomonas mobilis (strain ATCC 31821 / ZM4 / CP4)|TrEMBL
MQLPFRLGSRGSPLALIQARSVASALCAAHSWSEDAVVIVPIRTSGDKNRHQALADIGGK
ALWTKELDIALTTGQIDAAVHSMKDVETFRPSHISIAAMLPREDVHDRLIGIPSLEVLPY
SGCVGTASPRRAAQIRRIRPDIEIKLLRGNIDTRLEKLANKQFDATLLAAAGLIRLGRND
VGYDVPLDQMLPAAGQGAIGIEALADSAAWEKVSIIDHYPTHLAVQSERQLLLRLNADCH
SPIAVFAEILEKNIRLRACLYTENGKFSASIDKEISQPSDAFEVGSLLLNQSPPEVQALF
LPRVLSER
>A1FB19|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae 2740-80|TrEMBL
MRSASGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKR
LELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNL
TLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLS
QGAKEILERLYCDHE
>E8NBZ9|hydroxymethylbilane synthase|EC 2.5.1.61|Microbacterium testaceum (strain StLB037)|TrEMBL
MSAPLRLGTRRSALALAQSQMVADAVAAASGREVELVPIVSEGDVNRASLSQLGGRGVFA
NGLREALAAGRCDFLVHSLKDLPTAQPEGLVIAATPPREDARDVVITRDGTPLHALEAGA
RVGTGSPRRIAQALRHNPRLDIRDIRGNVDSRLARVRDGELDAVILAAAGLSRLGGELGG
LQSEPLGLAEWPTAPGQGSLAVETRTDIDADILAALSALDDEVTRAAITAERTVLSVLDA
GCHAPVGTHASIVDGDLRLRAVVYALDGAHRIGIDRTVRVEPLRGEPERVRPVPGVPEPW
VPEPGVPEREVPGYVEPGRAEQGYARETGSGNGAGAADDGGLIARAARIGREAARRLLER
GAADLVPRESTT
>F7YZ86|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus coagulans (strain 2-6)|TrEMBL
MRTIVVGSRRSKLALTQTKWVVAKLEQLGLPFRFEIKEITTKGDKVLDVTLSKVGGKGLF
VKEIEDAMLHHEIDMAVHSMKDVPAVLPDGLVIGCIPEREDVRDALISKNGTPFSGLKEG
AVVGTSSLRRGAQLLAVRSDIRIKSVRGNIDTRLEKLKNGDYDAIVLAAAGLKRMGWSAD
TVTEFFDPDICLPAIGQGALAVECRADDGELLDALRELESAETAETVRAERVFLDKMEGG
CQVPIAGLAKKTAEGISLTALVASPDGKTVYKETVVSRNPVTAGEKAADILSRQGAKALI
EQVKAELGQP
>E1UMG2|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / BCRC 11601 / NBRC 15535 / NRRL B-14393)|TrEMBL
MRTIKVGSRRSKLAMTQTKWVINKLKELNPSYNFEIQEIVTKGDRILDVTLSKVGGKGLF
VKEIEQALLHQEIDMAVHSMKDMPAVLPEGLVIGCIPKREDPRDALISKGHQKLDDIKEG
GIIGTSSLRRSAQILAERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKDD
VVSEFLEPDRCLPAVGQGALAIECRESDEELLKLFAQFTDEYTKRTVAAERAFLHAMEGG
CQVPIAGYASVNDRDEVELVGLVASPDGKTIYKETAAGHDPEEIGKRCAAMMSEKGAKAL
IDSVKQELDQDGK
>H3ZV57|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-125|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>G4CQF7|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria wadsworthii 9715|TrEMBL
MNIPKKLVIASRESRLAIWQAEHIQARLQALYPECEVSILGMTTRGDQILDKTLSKIGGK
GLFIKELEQALLDGRADLAVHSLKDVPMELPQGFALAAITERASPFDAFVSNQYERLEDL
PKGAVVGTASLRREAQLRARFPHLNVRPLRGNLQTRLEKLDKGEYDAIILAEAGLQRLGL
ADRIRTVLSPADSLPAAGQGVLGIEIAANRYDLFEILNPLNHPLSNACVTAERALSRALG
GSCQIPLAAYCTQEDGLLTLRGMVGHPDGSVMLEAYAQAPLAYADALGRAVAKKLADDGA
EDLIAAVLGEQNTNS
>I1VNV4|hydroxymethylbilane synthase|EC 2.5.1.61|Pasteurella multocida subsp. multocida str. 3480|TrEMBL
MVVMMTRKSLRIATRQSPLALWQANYVKACLEKIHAGLVVELVPMVTKGDVILDTPLAKI
GGKGLFVKELEQALLKGEADIAVHSMKDVPMQFPAGLMLSTICQREDPRDAFVSNSYRTL
MELPAGAVVGTSSLRRQCQLKQLRPDLHIHSLRGNVGTRLAKLDNGDYDAIILAAAGLIR
LGQQQRITSLIDVTQCLPAAGQGAVGIECRQEAEIELLLAPLADPETTACVLAERAMNRH
LQGGCQVPIAGYAIIEEGQLFLRALVGEVDGSSILRAEGRSAVADAETLGIQVAEKLLQQ
GADKILQTLYSN
>C0XZV5|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei Pakistan 9|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>H2GV57|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain ATCC 27012 / C7 (beta))|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>A9M205|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup C (strain 053442)|TrEMBL
MNALNMNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSK
VGGKGLFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALATIGERANPFDAFVSNQYTR
LEEMPEGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQ
RLKLDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALA
RALGGSCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLA
DDGAQELIGAVLNTEN
>Q05YJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. BL107|TrEMBL
MALTELRIASRRSQLAMVQTNWVKAELEKAHPGLTITVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLIGRADIAVHSLKDLPTNLPEGLMLGCITEREDPADALVLHAKNKHLNLA
TLPEGAVVGTSSLRRLAQLRHHYPHLEFKDVRGNVITRLEKLDSGAYDCLILAAAGLGRL
GFADRIDQSIPGDISLHAVGQGALGIECVENKPEVMDIIKVLEHGPTSQRCLAERAFLRE
LEGGCQVPIGVNTRFEGDQLILTGMVASLDGKRLIREKASGPSTDPESIGLALATTLKGL
GAGEILKEIFDAVRPEA
>G4PB80|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus subtilis subsp. subtilis str. RO-NN-1|TrEMBL
MRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGLF
VKEIEQALLNEEIDMAVHSMKDMPAVLPEGLVIGCIPEREDPRDALISKNRVKLSEMKEG
AVIGTSSLRRSAQLLIERPDLTIKWIRGNIDTRLQKLETEGYDAIILAAAGLSRMGWKQD
VVTEFLEPERCLPAVGQGALAIECRESDEELLAMFSQFTDEYTKRTVLAERAFLNAMEGG
CQVPIAGYSVLNGQDEIEMTGLVASPDGKIIFKETVTGNDPEEVGKRCAALMADKGAKDL
IDRVKRELDEDGK
>G7BEF5|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-43A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>H4LJN0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC2E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H7TR91|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 1909|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>D2R3S6|hydroxymethylbilane synthase|EC 2.5.1.61|Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128)|TrEMBL
MSDAPKLRLGTRASPLARWQADWVRDQLIAAGIDVEMILITTEGDQQTSQPLGQIGGQGL
FTKEIQRRLLAGDIDLAVHSLKDLPTLPIDGLSLAAVPEREDTADILIGPAGTSLATLPS
GAKIGTGSLRRKAQLLHARADLEILDIRGNVDTRLRKLDEGQYHAIILAAAGLKRLKLDD
RMTERLEAPLMLPAVGQGALGIESRSDDPTTRKLLAPLSHAPTLQAVIAERSLLAALRAG
CLAPVGAHAQVVDGQLTLAAVVLSIDGQSRLFASLTSAPADAAQLGEEVAELLRQQGATE
LLASSRGNRLD
>F2F2G0|hydroxymethylbilane synthase|EC 2.5.1.61|Solibacillus silvestris (strain StLB046)|TrEMBL
MRKIIVGSRKSKLALTQTNWFINELKEAGVPFDFEVKEIVTKGDRILDVQLSKVGGKGLF
VKEIEQALYDKEIDFAVHSMKDMPAVLPEGLIIGCIPPREDARDAFISNGHVKFADLPKG
AIVGTSSLRRSAQLLQARPDLEIKWIRGNVDTRLKKLETEDFDAIILAAAGLKRLGWSDE
VVTEYLDTDICLPAVAQGSLGIECRADDTELLEQLTKLTDATTWATAHAERSFLAAMDGG
CQVPIAGYATVEGDTITLTGLVAAPDASVTYKETLTGTDADAVGKAVAAKLTEQGAFDLI
QKVKAELDAE
>H4EQ95|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1750|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>C5QT48|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis M23864:W1|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDELKEIEPDLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKDIDMAIHSLKDVPSIIPEGLTLGCIPDREVPFDAYISKNHTPLSELPEG
SIVGTSSLRRGAQILSKYPHLEIKWIRGNIDTRLNKLETEDYDAIILAAAGLRRMGWSDD
IVTTYLDKDILLPAIGQGALGIECRSDDEELLDLLKKVHNHEVAQCVTAERTFLSEMDGS
CQVPIGGYATIDGNSQIEFTGLIMTPDGKERYEHTARGHNPVELGQEVSRVLKEQGAYEI
IRKLNEEN
>E9ZW49|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis N1568|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>F9BV35|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae BJG-01|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDHIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>H2CHC5|hydroxymethylbilane synthase|EC 2.5.1.61|Leptonema illini DSM 21528|TrEMBL
MFRIATRGSDLALAQTEYIQARLESLGYKTEQLIVKTTGDVNLAPFALASGDERKGLFTK
EIEDALLAGEADIAVHSYKDLPSVSVPELMIAAIPQRLDSRDYFIFKKKDQVSDTFPYIR
ADARIGTSSVRRRSQLLHLLPALQVMELRGNVPTRVRRLFEEGGPEGILLSGAGVQRLIE
QKRFVEEHLLEQLAIMPVDVETLVPAPAQGTLAVQCRVADSAARDALAKLHDSSLAEILS
VERGVLAALEGGCHLPLGIQAHARDGFVEASVYLGKEFLKTRYPYTVQFTRRHAEPAVLR
EFLIAELKDASTPLYVFGKKDRMQSLSDSYKEARCIGVIETRPLLERLPELPDQTVIGCF
SADAVRLIEQLDARWFKNLTFVWGVPGEKTAEMLLQRGVRSQQIVIGDDGTGAGLARSLL
AARESRLVGRRIVGLSAAAGREEFYDIISAGGFQPERVEAYATEAIEIPASTIASIQDDA
FLVFGSPSSFHAFAASLDRVKRDWSKGWRICSIGKTTSEAIRLYSQERGVAHLSEPYMTA
VEPDYDRIIKQILGR
>C0XUE8|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium lipophiloflavum DSM 44291|TrEMBL
MLHIGTRGSHLATTQAGHVRDDIIAAGHDAELTIVTTPGDLSQAPVERIGVGVFTSALRD
ALFRGEVEIAVHSFKDLPTADEPRAHIVVPAREDNREALIARDGMQLADLPQGARVGTSA
PRRISQLKALRPDLDIRPLRGNIESRMGRVTSGELDAIVLAYAGLLRAGYGDRATQLFDA
SEFLPAPAQGALAVECRSDDAETRAVLDPLMDAATALQVSAERHVLATLEAGCTAPVAAH
AFYDGGELSLRAGVFALDGSHQLVESGSVTVADTLDREAARGLGRELASRLLDAGAAELM
A
>C0XUE8|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium lipophiloflavum DSM 44291|TrEMBL
MLHIGTRGSHLATTQAGHVRDDIIAAGHDAELTIVTTPGDLSQAPVERIGVGVFTSALRD
ALFRGEVEIAVHSFKDLPTADEPRAHIVVPAREDNREALIARDGMQLADLPQGARVGTSA
PRRISQLKALRPDLDIRPLRGNIESRMGRVTSGELDAIVLAYAGLLRAGYGDRATQLFDA
SEFLPAPAQGALAVECRSDDAETRAVLDPLMDAATALQVSAERHVLATLEAGCTAPVAAH
AFYDGGELSLRAGVFALDGSHQLVESGSVTVADTLDREAARGLGRELASRLLDAGAAELM
A
>A3SRQ1|hydroxymethylbilane synthase|EC 2.5.1.61|Roseovarius nubinhibens ISM|TrEMBL
MKIGTRGSPLALAQAYETRDRLVAAFDLPETAFEIVIITTTGDRVIDRPLKEIGGKGLFT
REIEDALLTGDIDLAVHSMKDMPVLQPEGLIIDCYLPREDVRDAFICPTGRNLSEMAPGT
KVGSSSLRRRAQVLVAHPQLEVVEFRGNVQTRLRKLDEGVAACTFLAMAGLNRLKRTEVI
TRALEPEEMLPAVAQGAIGIERRRDDSGAAMMLEAIHHGPTGQRLAAERAFLAALDGSCE
TPIAGLAELQGGTLRLRGEILRPDGSERLCDDRSAPVEDGAELGRAMAVDLLAQAGPDFF
DWRG
>G9AQZ7|hydroxymethylbilane synthase|EC 2.5.1.61|Pantoea ananatis LMG 5342|TrEMBL
MVTKGDIILDTPLAKVGGKGLFVKELEQAMLENRADLAVHSMKDVPVAFPEGLGLVTICQ
RDDPRDAFVSNHYASIDELPQGAVIGTSSLRRQCQISARRPDLVIRSLRGNVGTRLSKLD
AGEYDAIILAAAGLNRLGLADRIRQPLPADISLPAVGQGAVGIECRLDDSTLIALLQALN
HDDTAVCVKAERAMNTRLEGGCQVPIGSFAVLEGDELWLRGLVGAPDGSVMVSGERRGPR
DQAEQMGISLADELLNGGAREILRDVYQGQPPV
>F4BFE4|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella cf. novicida (strain Fx1)|TrEMBL
MKQITIASRESKLALWQTNFVKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNVQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELYNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>Q132J6|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodopseudomonas palustris (strain BisB5)|TrEMBL
MEHVVKIPVRIGTRKSVMALAQTEDIAKQLRAAASELDVEIVKFETVGDSDQISKLLPHG
GKGGAFVAEIRAAVIAGQLQAAMHSLKDMPGNEDTPGLVIGATLARDPATDALVLREGLT
LEELKKSRGKGYTIGTNAVRRAAYAKRLFPEVNVIHFRGAADTRIRKLDAREKQRLPDGG
EVGPADALIMARAGLERVGFVDRIVHDFTPQEMLPSAGQGIVAVECAVDDWQTRRYLAMI
DDPKSRLCCDAEREVLWVLNGHCNSPMAAHSTVNGAEMTLHASVLDEEGGLFIETTRSGP
ANRPRELGRAVGLDLLDKGAAAVIEKTRPE
>C5NJU1|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei PRL-20|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>E6J9T0|hydroxymethylbilane synthase|EC 2.5.1.61|Dietzia cinnamea P4|TrEMBL
MSSRTLKVGTRGSTLATTQAGHVRDALIAAGYPAELVIVRTRGDVVMAPVERIGVGVFTL
ELRAALERGDCDIAVHSYKDLPTARDDRFAPIAVPPRVDPSDVLIARDGLTMETLPQGAR
VGTSAPRRRSQLAALRPDLDLHPLRGNIDTRMGYVTSGDLDAVVLAAAGLDRTGAGERAT
HRFGIDEMLPAPAQGALAVEARADDTEAIAALAVVDHLPSRVRIAAERTLLRDLEAGCTA
PVGARAELSGTDSARSDFAGTDPGADAPAADAVLTLHAVVAAHDGTTVLRTSGTTVPAEH
PDGPVAAAEELGRRLAAELLDRGASDLMSAESPEQRPPLVPRESTTAPPTVTDP
>E6J9T0|hydroxymethylbilane synthase|EC 2.5.1.61|Dietzia cinnamea P4|TrEMBL
MSSRTLKVGTRGSTLATTQAGHVRDALIAAGYPAELVIVRTRGDVVMAPVERIGVGVFTL
ELRAALERGDCDIAVHSYKDLPTARDDRFAPIAVPPRVDPSDVLIARDGLTMETLPQGAR
VGTSAPRRRSQLAALRPDLDLHPLRGNIDTRMGYVTSGDLDAVVLAAAGLDRTGAGERAT
HRFGIDEMLPAPAQGALAVEARADDTEAIAALAVVDHLPSRVRIAAERTLLRDLEAGCTA
PVGARAELSGTDSARSDFAGTDPGADAPAADAVLTLHAVVAAHDGTTVLRTSGTTVPAEH
PDGPVAAAEELGRRLAAELLDRGASDLMSAESPEQRPPLVPRESTTAPPTVTDP
>F5R4R6|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri 2930-71|TrEMBL
MVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICE
REDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALN
HHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAP
QDAEQMGISLAEELLNNGAREILAEVYNGEAPA
>A1W9V6|hydroxymethylbilane synthase|EC 2.5.1.61|Acidovorax sp. (strain JS42)|TrEMBL
MPAGAETDAAMTTPSPSLPSIVIATRESQLALWQAEHVQSLLRARGHAVALLGMTTRGDQ
ILDRTLSKVGGKGLFVKELEVALEEGRADIAVHSLKDVPMELPQGFALACVMEREDPRDA
FVSPGYASLDELPHGAVVGTSSLRRQALLQALRPDLQIEPLRGNVQTRLRKLDEGQYAAI
VLAAAGLKRLGLHERIRAVFTPEQMLPAAGQGALGIEIRGDRHDLREALAPLAHERTWLT
VTAERAVSRAMGGSCSMPLAAHGQWDGDTLSLRAAWGDVAARVPLVRAEGAAPVHTLEQA
DALGLAVAAQLRTAGAVGAL
>H5RQU8|hydroxymethylbilane synthase|EC 2.5.1.61|Nocardia brasiliensis ATCC 700358|TrEMBL
MTLVQEEDTVTAANMRSPWRIGTRGSLLALTQAGTIRDELVAAGHPAELVVIKTAGDLSA
EPVQQIGVGVFTSALRDELVAGTIDIAVHSYKDLPTAQDERFTIAAIPAREDPRDALVAR
DGLVLGELPPGAKVGTSAPRRASQLRALGLGLDIVALRGNLDTRLRKVSEGQLDAVVVAK
AGLARIGRLDAVTEALEPVQMLPAPGQGALAIECRSDAAELIEALAAFDDAATRAAITAE
RALLAELEAGCSAPVGALAEVVESIDDDGRIFDELSLRGCAAAVDGSDVLRASVVGAPEN
AEQLGRALARELLELGARELLSVPEPDAGSSTSAVSAPATDFTQPSPMENSQ
>H5RQU8|hydroxymethylbilane synthase|EC 2.5.1.61|Nocardia brasiliensis ATCC 700358|TrEMBL
MTLVQEEDTVTAANMRSPWRIGTRGSLLALTQAGTIRDELVAAGHPAELVVIKTAGDLSA
EPVQQIGVGVFTSALRDELVAGTIDIAVHSYKDLPTAQDERFTIAAIPAREDPRDALVAR
DGLVLGELPPGAKVGTSAPRRASQLRALGLGLDIVALRGNLDTRLRKVSEGQLDAVVVAK
AGLARIGRLDAVTEALEPVQMLPAPGQGALAIECRSDAAELIEALAAFDDAATRAAITAE
RALLAELEAGCSAPVGALAEVVESIDDDGRIFDELSLRGCAAAVDGSDVLRASVVGAPEN
AEQLGRALARELLELGARELLSVPEPDAGSSTSAVSAPATDFTQPSPMENSQ
>H5T7N7|hydroxymethylbilane synthase|EC 2.5.1.61|Glaciecola punicea DSM 14233 = ACAM 611|TrEMBL
MQKTSMQTTKSVIRIATRKSDLAMWQAHYVQDQLLKHFPNLTIELVPMSTQGDRILDSPL
AKIGGKGLFIKELEVAMQDGLADLAVHSMKDIPVAFPDEFGLHCICERENPFDAFVSNAF
ARFDDLPQGAVVGTSSLRRQAQLKAVRPDLTIKDLRGNVNTRLHKLDKGEYDAIILAAAG
LIRLDMKARIKHELDPLMCLPAVGQGAVGIECRNDDEALIAMLQKLNHSETALRVSAERA
MNAKLLGGCQVPIGSFAQFSYGDKKGIGELSMSALVASPDGTKILKTSAKINCAVDDIAA
AKKVGVSLADALLSQGARAILDAL
>E0MV77|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium accolens ATCC 49726|TrEMBL
MFQIGTRGSKLATTQAGHVRDWLIDAGFDSELHIVTTAGDTNMAPVERIGVGVFTQALRE
ALCRGECDIAVHSFKDLPTAEDDRFRLVI
>E0MV77|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium accolens ATCC 49726|TrEMBL
MFQIGTRGSKLATTQAGHVRDWLIDAGFDSELHIVTTAGDTNMAPVERIGVGVFTQALRE
ALCRGECDIAVHSFKDLPTAEDDRFRLVI
>H5MML6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC13E|TrEMBL
MVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICE
REDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALN
HHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAP
QNAEQMGISLAEELLNNGAREILAEVYNGDAPA
>I4AAX1|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfitobacterium dehalogenans ATCC 51507|TrEMBL
MQPVIILTKVKGEHMRSIKIGTRDSQLALWQAEWVKGKLEEHYPEGEFVLVPMKTKGDKI
LDVPLAKIGDKGLFTKELEVGLLNGEIDCAVHSLKDLPTVLPQGLEIAAFCEREEPRDVF
LSKDGTPLAELPAGSVIGTSSLRRKAQLQNYRSDLVFADLRGNLQTRWRKLQESNMAGIV
LAAAGVKRLGWEERITEYISEEIMLSAVGQGAIAVEIASHRAEVREMLDLLNHQDTERAV
KAERTLLYRLEGGCQIPIGAWAVTEGQQIVLKGMVASLDGQRILKVSLSGDNPEELGRKA
ADKLIAQGAMEILQEIRTTFDNTQHQG
>H7X6J5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 51494|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESILRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>F3SZU4|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU144|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRIGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>E5ANG7|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454)|TrEMBL
MRSAPRAPICTRGWRRCATCARRWPWKPSGPCRAHSVAAARCRSPRMRSGRVMCCNCGRR
LPRPTAAAYWPRRAARRRRIRPVRWRLACTWYSSCRRRVRCKSCSNCLTRRATEPRDGGR
PIVTQASLPPTSQSAAAGDAGAPVAARPTVVITRPAGQSAELLTALAATGLDGFEFPLID
ITDATDNAPLVDGLLDLERYALAVFVSPNAVDRAFAALAAARPKASPESASPVDVPPADA
LSADASSADTPSAHASAATVPPPAFSWPTTVPVAGVGPGTVRALARHGVQPHTHRIIAPG
DAVRVALQAPVYDGGAGVSYAGEPPRRDDTPAVQVSSDSYASGDAPRYDSEALIDALATA
FAPHGLTALQGRHVLLVRGDGGRELLAETLRAHGAIVQALGAYQRRLPEPSFDAWQRVHA
LLAGQPHAWVLTSSEGVRNLEELAREHLNRDEIVALKRAPIVTPHPRIGDTARKAGFDTI
TVSGAGDQAIVGALRTVFSPITQAASFSKTQSQSAQLSMTDSKDSQPAPGGAPQAAQPAR
PAAANVPPAAPFPPYESKRRRRSVSTALAWIGAVLVLAGAGAGGYVLERKVERLQQQLIV
RQQASDAQSRDTRLKADEAASAVRQLDSQLAQLAGRVGDVQTQHQALQASLQDLAKDRDD
WTLAEVEQTISSASQQLQLTGNVGLALLALQSADTRLAASTGAQVIAVRKAIAQDIDKLK
AAPSVDLAGLAIKLDDVIAQVDALPLAGEAPAVPLKSRTGTPADVAQVAAANGEPRWKVW
WHTFAADVMAQLTGLVQVRRIDNADAMLVAPDQGYLLRENVKLRLLCARVALLSRDEKLM
KADLQAAQQALARYFDPSAQATHNARERLDQVQKGAAHIELPNLEASLNAIHQNKGRG
>A8TB88|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio sp. AND4|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALQSAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPIDFPDGLGLVTICEREDPRDAFVSNTYNNIDDL
PQGAVVGTCSLRRQCQLKEYRPDLVIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRIDDERLRKLLEPLNHRDTADRVRCERAMNLTLE
GGCQVPIGSYSLLDGDNIWLRALVGEPDGSLIVRGEIHGHRNDAEALGVQLANELLANGA
RDILTKLYTDHE
>B4TB32|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella heidelberg (strain SL476)|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHS
LDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELL
ENGARAILTEVYNGETPA
>E7TS07|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC1212|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>I0ENR3|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter cetorum (strain ATCC BAA-429 / MIT 00-7128)|TrEMBL
MEKLLIGSRGSELALWQANYIKQRLKTECSIESEIKIIKTKGDKILDTPLNKIGGKGLFT
KELEELLLSGEIDLAVHSLKDVPVVFENELDLACITKRADVRDTFLSIKYSDLMSLPKGA
KVGTTSLRRSMQLKFKRKDLDTESLRGNVQTRLKKLELGAFDAIILAEAGLQRLEIKGAK
YRKAFSVDEMIPSMGQGALGVEMLKSHKHFSTLQKLNDEESAFCCNLEREFVKALDGGCQ
IPIGVHASIINDEVKIQAILGLPNGEQVISKEKQGKKVRAFLLVEELLEEFIASGAREIL
DKAQLF
>E8IU59|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O55:H7 str. USDA 5905|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F3EY24|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. mori str. 301020|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDELP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
NRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDPAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPAGSVLLHAEARAPQTSAQALGVQVAEALLAQGGA
DILKAVYGEANNE
>F0ITI4|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK160|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKALHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQKLADLPE
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRQLLATVQDDKTAAEVAVERAVLAQM
NADCTFPIAAFAQKKGQAYQLEAMLAKEDGQCVFVSLQGQDGQELAEQAVRQLADKGAVG
MPWLKK
>E8VQH0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio vulnificus (strain MO6-24/O)|TrEMBL
MTHSTPIRIATRKSPLALWQAYYVKDALQKAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYHHVDEL
PQGAVVGTCSLRRQCQLKAYRPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRTNDERILKLLEPLNHTDTADRVKCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEIRGPRAQAEQLGVQLANQLLDEGA
REILTKLYQDHE
>F2G2T7|hydroxymethylbilane synthase|EC 2.5.1.61|Alteromonas macleodii (strain DSM 17117 / Deep ecotype)|TrEMBL
MSHLNTTRTVRIATRKSALALWQAEYVKAKLLEHYPSMTVELVPMSTQGDKILDTPLAKI
GGKGLFIKELEIAMLEGRADIAVHSMKDVPVEFPEGFGLHAICERENPFDAFVSNNHDSL
DALPEGAIVGTSSLRRQCQIRKYRPDLIIKDLRGNVNTRLAKLDAGEYDAIILASAGLIR
LKMQSRIRMALPADISLPAVGQGAVGIECRNDDEELIALLQALNHADTHTRVTAERAMNE
RLEGGCQVPIGSFATLDNDVLTLTGMVGKPDGSELLFASATASREKAKDMGIEVAEALLE
QGAGEILKALYS
>D1Q3H5|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis biovar Orientalis str. India 195|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>B0VDE1|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii (strain AYE)|TrEMBL
MFDQPMLEFMKTLKIATRQSPLALWQAEHIRARLQERHPDLTVELVKFVTQGDKILDTPL
AKIGGKGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQF
EKFADLPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAG
LKRLGLAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLALIQPLLHPETDVCVRAERA
FNAYLEGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARN
LLDQGAGDLLKALY
>D7DDC0|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar D (strain D-EC)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>F0S2Y2|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfurobacterium thermolithotrophum (strain DSM 11699 / BSA)|TrEMBL
MKIRIGTRKSKLALWQSEWVKEQIEKKFPEVEVELIKITTKGDKILDVPLAKIGDKGLFT
KEIEDAMLKGEVDIAVHSLKDVPSKLPEGLKLIAFSDREDPRDALLSCGKYTLDTLPEGA
VVGTSSLRRKAQLRILRPDLEIRDLRGNVDTRIRKLKEEQYDAIILAAAGVKRLGWENEI
DEILSSDKMIPSVSQGILGIEGREDDPEIERIVKEAINSRESEIAATVERAFLRTVEGGC
QVPLGCYAVVVENRVHVRAFISDLNGRFYYKEEGVFKVENLEEADMVGTGVAERLLSAGG
KKILDELMKCQ
>H4XT53|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC7C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C4XJU4|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)|TrEMBL
MREKLVIATRGSKLALWQANHVADRLRQTHPGLAVDLLPIKTKGDIILDVPLAKVGGKGL
FVKEIEEALLDGRADLAVHSMKDVPAEQPAGLVVGIVPEREDPCDRLLSVAYDSLAALPQ
GATVGTSSLRRKAQLLALRPDLAIVDLRGNLDTRVKKLLDGQFDAIIVAAAGLNRLELSA
PKAVRLGPPEFLPAAAQGALGIEYRLDDPETAAMLAFFDHPESHDAVAAERGFLGHLEGG
CQVPIAAHAVIDGDMIHLEGLVADPETGQTFREAASGPRSQATALGVAVAEAVLARGAKA
VLDAVYKAGAS
>Q07S27|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodopseudomonas palustris (strain BisA53)|TrEMBL
MAIPVRIGTRKSVMALAQTEDIARRLSAAASELDVEIVKFETVGDSDQVSKLLPHGGKGG
AFVAEIRAAVIAGKLEACMHSLKDMPGNEDTPGLIIGATLSRDPATDALVLRKGLTLDEL
KKSRGKGYTIGTNAVRRAAYAKRLFPEVNIIHFRGAADTRIRKLDNGEMQRLPGGGEVGP
ADALIMARSGLERVGFVDRIVHDFTPQEMLPSAGQGIVAVECAINDWQIRKYLAMIDDPV
ARLSCDAEREVLWVLNGHCNSPMAAFSTINGSDMTLSASVLDETGGLFIEASRSGPANRP
RELGRAVALDLLNKGAAAIIERTRPE
>A4FPY3|hydroxymethylbilane synthase|EC 2.5.1.61|Saccharopolyspora erythraea (strain NRRL 23338)|TrEMBL
MNKTLRIGTRGSALAMAQTSWVAEALEKAGYRTELVTVSTPGDRSMAPIAEIGVGVFTSA
LRDALADGEVDVAVHSYKDLPTAPDPRLSLAAVPVREDPRDALVARDGLTLGELPPGSVV
GTGSPRRAGQLKALGLGLEVRDIRGNVDTRMRKVTDGELDAVVLARAGLARVGRLAGITE
TLDPLQMLPAPAQGALAVECRVDDVDTEHLLQSVLDDQASRVAVAAERAMLAALEAGCSA
PVGALAEVVEDLDADGRVAQRLFVRGVVAVDDASGRVDLLRASVTGETTAAEQLGRELAA
QLLDARAALLSGPGQ
>D4ICI7|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia amylovora (strain ATCC 49946 / CCPPB 0273 / Ea273 / 27-3)|TrEMBL
MSDKILRIATRKSPLALWQAKYVQQRLIDCHPRLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELENAMLSGHADIAVHSMKDVPVAFPQGLGLVAICERDDPHDAFVSNHYASVDSLP
AGAIVGTSSLRRQCQLSARRPDLVIHSLRGNVGTRLGKLDAGEYDAIILAVAGLKRLGLS
GRIRQVMPAEESLPAVGQGAVGIECRLDDMRTIGLLAALNHDDTACRVSAERAMNTRLEG
GCQVPIGSYALLEGDRLWLRGLVGSPDGSQMVRGERRGSRADAEKMGISLAEELLDNGAR
DILAAVYQGNPPA
>E8VGC9|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus subtilis (strain BSn5)|TrEMBL
MRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGLF
VKEIEQALLNEEIDMAVHSMKDMPAVLPEGLVIGCIPEREDPRDALISKNRVKLSEMKEG
AVIGTSSLRRSAQLLIERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKQD
VVTEFLEPERCLPAVGQGALAIECRESDEELLALFSQFTDEYTKRTVLAERAFLNAMEGG
CQVPIAGYSVLNGQDEIEMTALVASPDGKIIFKETVTGNDPEEVGKRCAALMADKGAKDL
IDRVKRELDEDGK
>H0BRP8|hydroxymethylbilane synthase|EC 2.5.1.61|Acidovorax sp. NO-1|TrEMBL
MSNSSSPLHIVIATRESRLALWQAEHVKALLQARGHTVELLGMTTKGDQILDRSLSKVGG
KGLFVKELEVALEEGRAHIAVHSLKDVPMELPEGFALACVMEREDPRDAFVSPRYENIDA
LPQGAVVGTSSLRRQVLLQALRPDLKIEPLRGNLDTRLRKLDEGQYDAIVLAAAGLKRLG
LESRIRATFAPTAMLPAAGQGALGIEVRSDRQDLIAALAPLAHQSTWLTVAAERAVSRAM
GGSCSMPLAAHGTFSNGVLQLDAAWGDVQAQAPLVRATASAAVTTLDQAEALGDAIAQQL
RAGGARGADFTQN
>H7VHA6|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli LMG 23342|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAIAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKILKFFKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>E2X510|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella dysenteriae 1617|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDARTRELLVALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>Q0K7M5|hydroxymethylbilane synthase|EC 2.5.1.61|Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)|TrEMBL
MSSATLSSSTAVVSRNLPQKLVIASRESRLALWQAEHVRAALQQYYPACDVSILGMTTRG
DQILDRTLSKVGGKGLFVKELEFAMDEGRADLAVHSLKDVPMELPEGFALTAVMEREDPR
DALVSSAYASLDEMPAGTVVGTSSLRREAALRSRYPQLVIKPLRGNLDTRLGKLDRGEYG
AIILAAAGLKRLGLGERIRALIPIDVSLPAAGQGALGIEILANRPELAQWLAPLNHQPTA
LAVSAERAVSRMLGGSCQVPLAAHARWEGDQLKLDAFVALPDGTRAIRAAASGPAVDLAA
AEALGQACARDLLAQGAEAILAALADSGDPAGSQAPA
>H3YDH1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-99|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H8IG29|hydroxymethylbilane synthase|EC 2.5.1.61|Pasteurella multocida (strain HN06)|TrEMBL
MTRKSLRIATRQSPLALWQANYVKACLEKIHAGLVVELVPMVTKGDVILDTPLAKIGGKG
LFVKELEQALLKGEADIAVHSMKDVPMQFPAGLMLSTICQREDPRDAFVSNSYRTLMELP
AGAVVGTSSLRRQCQLKQLRPDLHIHSLRGNVGTRLAKLDNGDYDAIILAAAGLIRLGQQ
QRITSLIDVTQCLPAAGQGAVGIECRQEAEIELLLAPLADPETTACVLAERAMNRHLQGG
CQVPIAGYAIIEEGQLFLRALVGEVDGSSILRAEGRSAVADAETLGIQVAEKLLQQGADK
ILQTLYSN
>A6E465|hydroxymethylbilane synthase|EC 2.5.1.61|Roseovarius sp. TM1035|TrEMBL
MTRDLPTPSHPLKIGTRGSPLALAQAFETRARLGAAFDLPEEAFEIVVIKTTGDQIIDRP
LKEIGGKGLFTREIEQAMLTGDIDIAVHSMKDMPVLQPEGLLLDTYLPREDVRDAFVSPT
VASLADLPAGSLVGTSSLRRKAQVLVAYPHLEVVEFRGNVQTRLKKLEDGVAACTFLAMA
GLNRLGRSEVATCAIDADVMLPAVAQGAIGIERRADDTRAAEMLAAIHHKETGQRLVSER
AFLAALDGSCETPIAGLAELNGSTLRLRGEILRPDGSESLTDDQSAPIEDGAELGRAMAA
KLLAQAGPGFFDWRS
>D5N165|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus subtilis subsp. spizizenii ATCC 6633|TrEMBL
MRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGLF
VKEIEQALLNEDIDMAVHSMKDMPAVLPEGLVIGCIPEREDPRDALISKNHVKLSEMKEG
AVIGTSSLRRSAQLLIERPDITIKWIRGNIDTRLKKLETEDYDAIILAAAGLSRMGWKQD
VVTEFLEPDRCLPAVGQGALAIECRESDEELLALFSQFTDEYTKRTVLAERAYLNAMEGG
CQVPIAGYSVLNEQDEIELTGLVTSPDGKIIFKETVTGNDPEEVGKRCAALMADKGAKEL
IDRVKRELDEDGK
>C5BLH6|hydroxymethylbilane synthase|EC 2.5.1.61|Teredinibacter turnerae (strain ATCC 39867 / T7901)|TrEMBL
MIAARFKNHQGPSVKHTLRIATRKSALALWQAEFVKSELCRHHPELAVELVPLTSRGDKI
LDVPLAKVGGKGLFVKELEQAIIAGEADIAVHSMKDVPMEFPQGLGLAVICEREDPRDAL
VSNKYSNLDAIPAGAVIGTSSLRRQSQLLAMRPDLEVTFLRGNVNTRLAKLDAGEYDAII
LASAGLKRLQMVDRIAEFIAPEVMLPAGGQGAVGIECRTDDQETLALLQPLHHGVTEQAV
LAERAMNRKLEGGCQVPIGGFAIHQDNQLWVRGLVADPDGSEVLYDQVIGDPADAETLGV
VLAEKLLAAGADAILKRVYGDASA
>F9S533|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio ichthyoenteri ATCC 700023|TrEMBL
MTHSSPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNSIDEL
PQGAVVGTCSLRRQCQIKERRPDIIIKDLRGNVGTRLGKLDAGEFDAIVLAAAGLKRLEL
EERIRSFMEAEESLPAVGQGAVGIECRLDDERLIKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYSLLDGDQIWLRALVGEPDGSQIIRGEIHGPRTQAEELGITLANQLLDQGA
RDILTRLYADHE
>G7BS55|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-48B2|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>I3XXJ8|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurospirillum barnesii SES-3|TrEMBL
MKKLIIATRGSKLALWQSEFVKAELEKAHPGLEVELSVMMTKGDKILDTPLAKIGGKGLF
TKELEEAMLRGEAHIAVHSLKDVPMEFPKGLKLGVITKREDVRDAMLSEKYGCLEELPQG
AVVGTTSLRRRMQLLSLRPDLVIKNLRGNVNTRIRKLKEGEFDAIILATAGINRLGLASE
VRYFSPISKEHIIPASGQAALGIEIVDDAEVEDLVSVLNDADAIVETMVERDFVTLLEGG
CQVPIGVNAQVFGDFLHVKAIIGLPDGSEMISEAMSGTRADFVTLGKALAQKVIDKGAKE
LLERAEKIALSEIF
>A3VER8|hydroxymethylbilane synthase|EC 2.5.1.61|Maritimibacter alkaliphilus HTCC2654|TrEMBL
MFRTILCALAVASFAGAVRADEAGTLTLDIAGETHSFTLWTDQSDWSGSETYASVNIYAR
PETDATREAYGILTLGFEVAGGSANAPEASLTRIDGDERVKLYSTDDAGGLSITPDTASV
SGEELTISGSFAGEMGISENYGRDIDLNDPLAVSGTFDVVLGPVE
>F2C7Q9|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK330|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKELHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLTFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSHLHIQPLETSLCLPAISQGALAVECREEDKELLQLLATVQDEKTAAEVAVERAVLAQM
NADCTFPIAAFAQKKGQDYQLEAMLAKEDGQCVFVSLKGQDGQELAEQAVRQLADKGAVG
MPWLKK
>I0UBJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus thermoglucosidans TNO-09.020|TrEMBL
MRKIIVGSRRSKLALTQTNWVIEQLRQLGAPFEFEVKEIVTKGDKILDVTLSKVGGKGLF
VKEIEHAMLNNEIDMAVHSMKDMPAVLPDGLIIGCVPPREDHRDVLISKNKETFADLPSG
AVVGTSSLRRSAQLLAKRPDLTIKWIRGNIDTRLAKLQTEDYDAIVLAAAGLVRMGWASD
VITEYLATDVCLPAVGQGALAVECRESDEELREWLQKLNDIDTERAVYAERAFLRQLEGG
CQVPIAGYAHVNNQNDIVLTALVASPDGKELYKETVSGPDPENVGTTAADLLIKRGAKAL
IDRAKEEMNR
>H7UY44|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 37/05|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>E7X686|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 531954|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I2Z2J2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 3003|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>A8EFJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei 406e|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>A3GPW4|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae NCTC 8457|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>F6BF35|hydroxymethylbilane synthase|EC 2.5.1.61|Methanotorris igneus (strain DSM 5666 / JCM 11834 / Kol 5)|TrEMBL
MKVIIGTRGSKLALAQTYQVADLLKSEGVETEIKIIKTVGDKVQNKTLSELGIGVFTKEL
DLAMLNNEIDIAVHSLKDVPTVWNENLIIAATPKRESYHDLIIWNKDNEKVEEFLNGKCK
AVVGTSSIRRKEFLKIMYPNIEIKLLRGNVDTRLNKLRNKEYDAIILAEAGINRLKINLN
EEFNFKRLDILPSPAQGAIGIAARKDDGEIIDILKKINDKKTFLEVTAERFALREYGGGC
QAPFGALAKYDEKLGKLELECAIVENGKIKRERREICCGVDDIECAKKLGMEVGRLLKQ
>F9LTG8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU109|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>C9Q2T0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio sp. RC341|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYAKIDDLP
SGAVVGTCSLRRQCQLKSARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLGLE
SRIRNFIEPEQSLPAVGQGAVGIECRLDDQRVRELLAPLNHTDTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDHIWLRALVGEPDGSQIVRGEIRGPRSEAEQLGITLAEQLLEQGAK
EILDRLYCEHE
>F3DX07|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. morsprunorum str. M302280|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFESLDALP
AGSIVGTSSLRRQAQLLARRPDLEIRFLRGNVNTRLAKLDGGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGRVLLHADARAPQTSAQALGVQVAEALLAQGAA
EILKAVYGEANNE
>G8TMG3|hydroxymethylbilane synthase|EC 2.5.1.61|Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10)|TrEMBL
MNKVIRIGTRESQLAVWQATQVQNLLAQHGFAAELVYIKSEGDIDLKTPLYEMGVQGIFT
RSLDIALLNDRIDIAVHSMKDVPTQLPKGIITASVLKRASYKDLLVYKIDAEAGNRQSAT
GNLKNSDFPFTTDDSRLTIATSSIRRKAQWLNRYPHHTIDNLRGNVNTRLKKLAESPWNG
AIFAAAGLERIGLRPEQSVELDWMLPAPAQGAIVVACRENSPYVFEACQLFNDEPTALCT
AIERDFLRALLGGCSTPISALANIVNGQVHFEGNILSLDGKEKATIEKTTAINNSNNLGT
IAAKELLANGGQAIADQIRNGK
>B3HYA4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli F11|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>Q2FTK7|hydroxymethylbilane synthase|EC 2.5.1.61|Methanospirillum hungatei (strain JF-1 / DSM 864)|TrEMBL
MPLRVGTRASELAKAQAVKVCTMLEDLGVDTELVFISTAGDEQTGVPLHEIGGQGVFVRA
LDDALVQNKIDLAVHSMKDIPAERPYGLVTSAILARDSPCDYIVTDHELDEITTLGTSST
RRTAQCRRNLPWADIRPLRGNVNTRLSKLQSGEYDAIMLAKAGLERLSMTLDGYQLDPRV
HVPSPNQGTIAVVSRTDPDVTDIISKIDDPKTRMDTLLERRVMEMIGGGCFTPLGIYCKD
RLMIAEVLSLEGDRHFRLERLVSDIDDADRFGLEVRERAGDLIREAYERLGITHG
>I5DDP1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli FDA517|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>A3UIQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Oceanicaulis sp. HTCC2633|TrEMBL
MSASDRSRVLVTRAEPGATRSCAALAERGFDAINAATAVLKAHEVALNLKGVSLIAVTSP
FGASCLATATSERRLPVIAVGDVTASRLREAGFEKVNSASGDARDLLAMIRERAPEGEVL
HVRGVDQTGDLSAELNARGIRARSEILYAAEPVSALPGAVWASLAAGATVLIHSAKGAER
FNDLANAADQVEALLAARIVAISTAAAEPLKSLGVARLKIARRPDEDALFDALENRPSAR
A
>F9RVI5|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio scophthalmi LMG 19158|TrEMBL
MTHSSPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGSVVGTCSLRRQCQIKERRPDIIIKDLRGNVGTRLSKLDAGEYDAIVLAAAGLKRLKL
EERIRSFMEAEESLPAVGQGAVGIECRLDDERLIKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYSLLDGDQIWLRALVGEPDGSQIIRGEIQGPREQAEELGITLANQLLDQGA
RDILTRLYAEHE
>E8T5K3|hydroxymethylbilane synthase|EC 2.5.1.61|Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1)|TrEMBL
MKIRIGTRKSKLALWQSEWVKAQIEKKFPDVEVELVKITTKGDKILDVPLAKIGDKGLFT
KEIEEAMLRGEVDIAVHSLKDVPSKLPKGLKLIAFSDREDPRDALLSCGRYTLETLPEGA
VVGTSSLRRKAQLRILRPDLQIKDLRGNVDTRIRKLKEGQYDAIILAAAGVKRLGWEEEI
DEILSPERMIPSVCQGILGIEGREGDSEVERIVREAVNSYESEVAATVERAFLRTVEGGC
QVPLGCYAVVNEDRILVRAFISDLNGRFYHKEEGVFRFKDLREADSIGVAVAERLLSAGG
KTILEELLKCQ
>F3RFT5|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes J1816|TrEMBL
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEVIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNRVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEVVHFKGLVGNADGSIILASEQAGANPSEIGNKVAEDLLSEGAD
TIIKELRNI
>I4GZA5|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 9806|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSQNQD
YQLDTLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDGDAEVLQVLKVLEHAPSRDRCYAERA
FLRELQGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VRDAGAGEILAQIFAEVGR
>A3S8F8|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfitobacter sp. EE-36|TrEMBL
MTVNLPTPENPMRIGTRGSPLAMAQAYETRARLAAAFEIPQAAFEIVVIKVTGDVIQDRP
LKDIGGKGLFTREIEEDLLAGKIDIAVHSMKDMPTIQPGGLLLDTYLPREDPRDAFVAPT
LSALDQLAEGAVVGTSSLRRRAQLLHQRPDLQVVEFRGNVQTRLKKLADGVAECTFLAVA
GLNRLGMQHVPATPIDDTLMLPAVAQGAIGIERRAGDLDTEAMLAAIHDTPTGQRLAAER
AFLLTLDGSCETPIAGLATLDGDTLHLRGQVLRPDGSEAIAGDRSGPIAQGGQMGVDLAQ
DLLAQAGPGFFDWHVKG
>D6ZK01|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125)|TrEMBL
MQTIGSTERPLVIGTRASALALTQTRAVASDLEQRGLHVQVQTFTTEGDINRASLASLGG
VGVFAAALRVALLEGHCDLVVHSLKDLPTVPVDGLVVAATPTREDPGDVLVARDSLSLAD
LPAGSRLGTGSPRRARQIAVARPDIELVDIRGNVPTRVGRVKGLAAVAEQAGLPSGKAAE
DLDGVVLARAGLRRLGMDDAITDSLEGTVIPAGGQGALALETRSELLDSDEGRNFAQILK
FVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGVVTWDKHTEAPSGRLELTARVIGNQGE
VLEVNGETTVLLGAEAAQRDFALAAAEQLGVDLAGELLEAGAATIADLKAAKSASTQTDA
NQTICNEKELWGE
>D7CY07|hydroxymethylbilane synthase|EC 2.5.1.61|Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24)|TrEMBL
MSRSFSPLADLPRARYTGVVRIATRKSALALWQATWVRERLAALGVATELVPLDTQGDRT
QEAGTPFRLMPGQGFFTKAVQDAVLEGRADVAVHSHKDLPSARLAGLELAAVTEREDPRD
VLLVRPGAARPESAALPLVEGAVVGTSAARRQAQLRHLRPDVRVAELRGNVPTRVRALRE
GRYDAVVLAAAGLARLALDLSDLTVYPLDPKRFVPAPAQGALALEIRRGDAELAALLTEL
HAPDAYQTVAAERGLMGMLQGGCQLALGAYAALQGGELELTAWYEGERVTVKHRSAEGAA
YLAFDALGRPAPARAAAKEP
>E7JJP0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli RN587/1|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNTYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>H2H2I3|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain CDCE 8392)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRANDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>A3ZDR6|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni HB93-13|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>F0IGF9|hydroxymethylbilane synthase|EC 2.5.1.61|Capnocytophaga sp. oral taxon 338 str. F0234|TrEMBL
MKKTLRIGTRDSELALWQARKVQSLLEALGYPTTLVPVKSQGDLTLDIPLYTMGITGVFT
KVLDVAMLQGVIDIAVHSMKDVPTTLPKGIIKGAILKRANVQDVLVYKENLDFLSHTHAT
IATGSLRRKAQWLRRFPTHLVENLRGNINTRLEKLHKSPWQGAIFAAAALERLDKKEVNA
FPLDWMTPAPAQGAIMVVSKAEDTYTKEALALINDQPTDIETNIERRFLKRLEGGCTAPI
GAKATLDGKTISFVGNLFSLDGKHAIEVKKTISLDDIENFPEACADEILLKGGADLMQEI
RKVMNIQK
>A9ZZP9|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis biovar Orientalis str. F1991016|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>H9Y896|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F3JF36|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. aceris str. M302273|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDQLP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGSVLLHADARAPQTSAQALGVQVAEALLEQGAA
DILKAVYGEANNE
>H6PEN6|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia canadensis str. CA410|TrEMBL
MTHSIRIGTRKSPLALIQTNLVIQQIKQFVPDINYKIVPITTSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEDLIIAAVLEREDPRDVFVCLKYKSIEELPQ
NAIIGSSAVRRKAFIEKIRSDLKVTVFRGNVDSRIKKLMNGEVDATILAYAGLKRLNAFN
PQYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLETCNQINHLTTFELIKPERAFLEYLDA
NCRTPIAAYSKYLDKDNIETDFMLGNLESSKITFHTETTNIKTSKEAGIKAAKIMLSELE
R
>A5XND0|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei JHU|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>E3IN27|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio vulgaris (strain RCH1)|TrEMBL
MKHLVIATRGSKLALWQAEHIKSLIETEHAGKVDVSLKIIKTKGDIILDVPLAKVGGKGL
FVKEIEEALLDGSADLAVHSMKDVPMELPEGLFLGCIPEREEPSDTLLSVRYASLDALPH
GARVGTSSLRRQSQLLALRPDLDIISLRGNVDTRLRKLMDGEFDAIVMATAGLKRLGLAA
PHHEVLAPPRFLPAVGQGALGIEFREDRADLRDMLAFLDHRPTRIRVEAERGFLAGLEGG
CQVPIAGHAVMTGDDNFRIEGLVADLKGERVIRRTLEGTGANARNRGLELASQVLADGAA
EILDEVYASGAADRQ
>B0RBL6|hydroxymethylbilane synthase|EC 2.5.1.61|Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667)|TrEMBL
MTDGPTTSAPTTTLRIGTRGSALALAQTRAIAAEITGASGLEVELVPVTTHGDTSRESLS
SLGGTGVFASALRESLLRGECDLVVHSLKDLPTAPYAGLTVASVPVREDPRDVLCARDGL
TLATLPRGARVGTGSPRRRAQILAERPDLDVVDIRGNIDTRLSRVTAGDLDAVVLAAAGL
ERIDRIGAATEHLELDRWPTAPGQGALALEIRTEDAETHSVVGRAVEAVDDPFTHAAVLA
ERGVLAALEAGCAAPIGAWATVTSARLALTAVVYRPDGTQRMAASHELDTAGLDLAQLGA
SASALSGPVSRELLDAGAADLAPLGGTR
>D3SVH6|hydroxymethylbilane synthase|EC 2.5.1.61|Natrialba magadii (strain ATCC 43099 / DSM 3394 / NCIMB 2190 / MS3)|TrEMBL
MRTRGTLRLATRGSTLARRQATLVKEALENRRYEVELVTVETTGDQIRDELIHRLGKTGA
FVRELDERVLEGDLDGAIHSMKDMPTEQPDDLVTAAVPERGRPGDYLITPEGATLEELPQ
GATVGTSSLRRRAQLLSERPDLTVEPLRGNVDTRLEKLLAPSLQAEHEERSEADKERKGN
TGEEDFEPEFDQTVDEWFDGLSELEKQALGREVETEYDAIVLAQAGLVRSGLDHYVDAQE
LPTGTFVPAPGQGALAVTATDGETATEIQSAIDHPRSRVETTVERTVLAELGGGCIAPIG
IYAIVQGEYVHATVSVFNRDGEESVAATRDLPVENHATAAREFAQDLADRGAAELIENAR
KETESESEPSQEDQPEGK
>B3C0S9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC508|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E8QWA7|hydroxymethylbilane synthase|EC 2.5.1.61|Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B)|TrEMBL
MLSPTTACSSSPLPSHRRVRIGTRGSPLARWQAEWVAARLRDAWPGLTVELVEIKTLGDR
DRNSPLASIGGAGLFTKEIQRALLDCRVEIAVHSLKDLPTQPVEGLILGAVPPREEPRDA
LIAPAHGLLEHLPAAARVGTGSLRRRAQLLWMRPDLEVVGVRGNVETRLNHALEGRLDAV
LLAVAGLRRLGLDSAITQTLGPPDFLPAVGQGALGIECRGDDPDTLALLAPLDDPASRAS
VLAERALLADLEAGCMVPLGAWGRSEADGLLALDAAVLDPAGRQRLAAHASGPANDPQTL
GLAVAAELRRQGAEALLRPCGEEPAKEPSSSH
>I0I3W2|hydroxymethylbilane synthase|EC 2.5.1.61|Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1)|TrEMBL
MSERIDAVRLGTRGSMLARWQTDYVAGLLAKAWPHLHIHVEVLHTQGDRVLDRPLPVIGG
KGLFTAELEEALHSGAIDLAVHSLKDLPIELASGLTIGAIPTRGAVHDVVISRSGHPLAQ
LPAGATVGTSSRRRSAQLLRACPHLRTIDIRGNVDTRIRKTLDPAGPYDAIVLAAAGIER
LGRPDAVTEALSLEIMLPAPGQGALAVQCRDDAAILRLLVPLEDPVTRVAVTAERAFLRH
VGGGCAVPVAAYAQITAGRLHLRGRVLSPDGRRCIEVEGDSHPDEPEMLGAKLAAQALAQ
GAASLLAEETS
>B1VEJ6|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109)|TrEMBL
MTNNRRLLVGTRGSTLATTQAGHVRQGMIDAGYDAELHIVHTPGDASQASQIPVAKVGVG
VFTETLRTALDERECDVAVHSFKDLPTAPDARFRAVVPKRVDSREVLISVDNKKLMELPE
GAKVGTSAPRRVSQLRALRPDLQILPLRGNIGTRMGRVGDDLDAVILARAGLERVGWLDK
AAESIDPELILPAPAQGALCVEVRADDEEAWNSVADQNHTPSYACVVSERTVLSTLEAGC
SAPVAAHATLNEQQNQLTVTGGVFAIDGSRKLLETRTVDIDLAGDWRAAAAGVGAEIGRI
LLDAGAAELVAEARES
>I2U0P2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 93.0624|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>D6YFA2|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar G (strain G/9768)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>A4FXQ7|hydroxymethylbilane synthase|EC 2.5.1.61|Methanococcus maripaludis (strain C5 / ATCC BAA-1333)|TrEMBL
MKLRIGTRGSTLAMIQTEYIAGLLNDLGVETEIIIVKTTGDKDQNKKLADLGLGVFTKEL
DNKMLENEIDIAVHSLKDVPTLWSEELQITATPKRESPDDIIIWRKDSDFDIEHDELNIG
TSSIRRTSFLQFTHPNLTPKLLRGNVATRINKLRTGEYDTIIMAKAGLIRQGIDLSEFNY
KKPEILPAPAQGVIGVASRKADTKINEILDKICDKKTYIEAAAERWALKEYGGGCQAPFG
AFAIYDTEDGILNLRCELVDEQGTIKRVKSNEGFIICTTDDVELAKELGARVGALFKEIE
TFTY
>F5LJQ7|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus sp. HGF7|TrEMBL
MRTIVVGTRQSALALTQTNQVIDELKELSRQSGIECEFELRKIVTKGDRILDVTLSKVGG
KGLFVKEIEQAMMDKEIDIAVHSMKDMPFELPEGLMVGAVPKRQDPRDVLITKGEKSLDE
LPQGALVGTSSLRRSSQLQHSRPDLRIQPVRGNIDSRLRKLESEGFDAIVLAAAGMHRIG
WQDRISAYVPPEVCVPAVGQGALCIECRADDEVVLNLLSKIQDDDTALAVRAERSFLGRL
NGGCQVPLGAYATVERTGGGTELSLTAMVGSPNGAELLKETLRGSDPEALGREAAEKLIA
RGADRILAEAYESGRIE
>H4SIM2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC5A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A4SSF7|hydroxymethylbilane synthase|EC 2.5.1.61|Aeromonas salmonicida (strain A449)|TrEMBL
MKQLIDMAARTLKIATRKSPLALWQANFVKDRLEALYPELQVELVPMSTQGDKILDTPLA
KVGGKGLFVKELETAMLEGRADIAVHSMKDVPVEFPEGLGLHTICEREDPRDAFVSNRFS
QIEALPQGAVVGTSSLRRQCQLRAARPDLVIRDLRGNVNTRLAKLDAGEYDAIILAAAGL
KRLEMAHRITAFIEPEQSLPANGQGAVGIECRLDDHELHTLLAPLEHAETRIRVLTERAM
NRALQGGCQVPIGAYALVQGDEVWLRGLVGSPDGSQVIHDEIRGPLADGEALGHTLAQRL
LAAGADVILAEVYRA
>F5WG36|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21310|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>D4HAK7|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes (strain SK137)|TrEMBL
MPLWCRRPAELSVNLSDCRLESASVLSATIGNMSAIRLGTRASTLATTQSEMVAGLLRSE
GLDVNLTTITTHGDTSTASLAAMGGIGVFASAIRAALLEGEADIAVHSFKDLPTGRPLGL
AIGAVPARADPRDALVARDGLTLHDLPQEASVGTGSPRRAAQLLAVRPDLTIVDIRGNVD
TRLGRVKGLGRYAKNGGKEDLDAVVLAASGLARLGHSGAVTEFLDPSVVLPAPAQGALAV
ECRTADSRHGKLAKALARIDDRRTRLAATAERAVLSHLEAGCAAPIGALAQLKPVSGKSL
QVLTLDVVVAAVDGSRTVREQVSVELPAEVEPALAAAHTLGVTAAEELLDDGAADVADLK
ASGSTR
>D3EX68|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain 04-02981)|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>B2ULP1|hydroxymethylbilane synthase|EC 2.5.1.61|Akkermansia muciniphila (strain ATCC BAA-835)|TrEMBL
MTSKNTLIIGTRGSALALAQADMVRAALSLRYPELDVRCEIIHTIGDRRTDVPLADVARV
SGMVDKGIFIKELETALRDGRIDVAVHSLKDVPSELAAGFTLAAVLPRAAVEDVLITKEP
DWNGSGTLATGSVRRRLMARTYWGSGLRFENLRGNVPTRLGKLVEHPGWDAVILARAGLE
RLGLYAPETLVEGRKLYMRPLPVEVFIPAVGQGIVGMECRSSDRETAEMLEGINDPESFA
CALAERAFLVRLGANCSTPVGVYAHPDGEELVLRAAYYVPGREEPFAVVIRGDRKAPEAL
GLRAFEELGLSGWRKTSSCSGCGEK
>I0JPF4|hydroxymethylbilane synthase|EC 2.5.1.61|Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / NBRC 102448/ NCIMB 2269)|TrEMBL
MKKIVIGSRKSKLAITQTEWVIEQLKNIDPSYEFEIKRISTKGDKILDVTLSKVGGKGLF
IKEIEQAMYDGEIDMAVHSMKDMPSEVASGLTVASVPIREDHRDAFVSNGNVALKDLHEG
AIVGTSSLRRSAQIKAVRPDVEVKWIRGNIDTRLRKLKEEDFDAIVLAAAGLKRMGWDDN
LVTEYLEPDVCVPAVGQGALAIQCRENDSSLRDFLMQINHEYTATTVSAERKFLHDLNGG
CQVPIGGYAYRKGSEIVLSALVGTPDGKTILHETVSGEDPLAVGKEAADRLKAQGAQEIV
DQAKEEYDQ
>E8RK43|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3)|TrEMBL
MRTLLRIGTRASLLAVTQSTWVKTQIEQAHPGTRVELVKITTKGDRILDVPLAKVGGKGL
FVKEIEDALLAGEVDLAVHSMKDVPTELPEGLHIGVIPVRETPYDAFLSKTCTTLADLPQ
GATIGTSSLRRKSQLMALRPDLDIVDLRGNIDTRLRKLDEGVYDAIILAGAGLRRLHLEH
RITALLEPTQMLPAISQGALGIELRQDDTELADGLRFLHHGETAVAVEAERAFLLRLEGG
CQVPIAAHATLDSGSVTLTGLIASVDGRQILKEATTGPAEQAARLGAQLAQTLLDRGGKA
ILDAVYCSASTSPHSPLSA
>I5SQ73|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4196|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F5XF75|hydroxymethylbilane synthase|EC 2.5.1.61|Microlunatus phosphovorus (strain ATCC 700054 / DSM 10555 / JCM 9379 / NBRC 101784 / NCIMB 13414 / VKM Ac-1990 / NM-1)|TrEMBL
MNVEQVNAEPVTTEQTITGETVRIGARTSPLARAQADQVAALLQARGFATEFVGITTTGD
VDLRSLTQIGGTGVFVSAVREALYERRIDVAVHSLKDLPTAPAAGLEVVATPPREDPRDV
LVGRTLDTLRDGDRIGTGAPRRAIQLAELGARLGIRLEAVEIRGNVDTRIGRAAAGEVDA
VILAAAGLRRLGRLEAPELSECDKCANDGLTVVKGLPAQILSVDDLIPAPGQAVLALEIH
ESLSHAKKAAMRTLDDLAARAESLAERAFLATLEAGCTAPVGARAVLEGVHGTSLDLTLR
VVIGRTVLNNLSESIKTAPPLRRRLSGTTTDASQFGAEAAKAILDELRTPQRPRQP
>G6Z1T4|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-06A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>E7B761|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia enterocolitica subsp. palearctica serotype O:3 (strain DSM 13030 / CIP 106945 / Y11)|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPIAFPEGLGLVTICERDDPRDAFVSINYAHLDELP
AGSIVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDKGEYHAIILAVAGLKRLGLE
TRIRYAMPAEESLPAVGQGAVGIECRLDDNFTRQLLAPLNHRETELRVCAERAMNTRLEG
GCQVPIGSYAELDGDTLWLRALVGAPDGSEIIRGERRGPAENAEQMGVELADELLSRGAR
EILAEVYQDNPPL
>A6GVP0|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)|TrEMBL
MAKKTIKIGTRDSELALWQAHHVEKMLNDLGHKTKIIAVKSQGDIILDKPLYELGITGIF
TKTLDIAMVNGDIDIAVHSMKDVPTALPQGIVQAAVLERANEKDILVYNNNLDFLNTQAT
IATGSLRRQAQWLHKYPNHKVVDLRGNVNTRMQKLQDNNWNGAVFAAAGLERINIKPENY
INLDWMIPAPAQGAMMVVAMGNDTYCLDALAELNHIETEITTYIERQFLRTLEGGCTAPI
GAYARFNEKDETIHFQGVLFSLDGSQKIEIKKIVEIQEWKQLGYHAGQEIFENGGVQLMK
TIKEKLKK
>F9ECK9|hydroxymethylbilane synthase|EC 2.5.1.61|Actinomyces sp. oral taxon 448 str. F0400|TrEMBL
MTRTVRLGTRGSALAVTQAGLVAHLIARRAADLGLDLAVKIVEIRTRGDVDPSALARLGG
VGVFAAALREALIDGDCDLAVHSFKDLPTGPVPGLRIAAVPQREDPRDALCTAGGASGRR
LDDLAPTARIGTGSPRRAAQLLAVRPDLRIVPVRGNVPTRLSRVLGKGVREDGPMGAARE
PDLDGVVLALAGLRRLELDGHVSEILSADSRTGAPVMVPAAAQGALAVETRDSLDREDPQ
LAQVLADLDDPATRAAATAERAVLARLGAGCAAPVGALARLTVEGGDALRLEAVVAALDG
RTVLRESAVGPLSEAQVLGTRVAQALLTAGATRVADLRAGSVSRKDLR
>F9ECK9|hydroxymethylbilane synthase|EC 2.5.1.61|Actinomyces sp. oral taxon 448 str. F0400|TrEMBL
MTRTVRLGTRGSALAVTQAGLVAHLIARRAADLGLDLAVKIVEIRTRGDVDPSALARLGG
VGVFAAALREALIDGDCDLAVHSFKDLPTGPVPGLRIAAVPQREDPRDALCTAGGASGRR
LDDLAPTARIGTGSPRRAAQLLAVRPDLRIVPVRGNVPTRLSRVLGKGVREDGPMGAARE
PDLDGVVLALAGLRRLELDGHVSEILSADSRTGAPVMVPAAAQGALAVETRDSLDREDPQ
LAQVLADLDDPATRAAATAERAVLARLGAGCAAPVGALARLTVEGGDALRLEAVVAALDG
RTVLRESAVGPLSEAQVLGTRVAQALLTAGATRVADLRAGSVSRKDLR
>F4D430|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori 83|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSMKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEVGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLEREFVKGLNGGCQ
IPIGVHASLMGDRVKIRAVLGLPNGKEVIAKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKVQLF
>C1F251|hydroxymethylbilane synthase|EC 2.5.1.61|Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)|TrEMBL
MMRIGSRGSQLALWQANHIAARLRTLGHEVTIEIIRTTGDALQHVTFAKVSTELGGKGIF
TKEIEEALREGRIDLAVHSLKDLPTDLDPAFTLAAIPERVDPRDALLSARYTSLASLPHG
ACVGTSSERRRAQLLVHRSDLRFQEFRGNVDTRIRKMVEGQADAIILASAGLERLGLTEY
RRECLAPEILCPAAGQGALAIETRADDAETLAILASLDHSATRYAVTAERTALASLGGGC
QVPIGIHCAPVPGADGAYAIQGVVAGAAAKAASSAAHPVIRVAFEHQQGLSPQALGRQLA
EELLRQGAQPFA
>A6AGW3|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae 623-39|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGNTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>Q4BZM7|hydroxymethylbilane synthase|EC 2.5.1.61|Crocosphaera watsonii WH 8501|TrEMBL
MVVSSRAIRIGSRKSQLALVQTYWIQEQLQKHYPDRQFDVETMSTQGDKILDVALAKIGD
KGLFTKELETAMLQNQVDFAVHSLKDLPTNLPEGLMLGCVTERVNPADALVVHEKHRDKQ
LDTLPEGSVIGTSSLRRLAQLRHHYPHLTFKDVRGNVNTRLGKLDSGEYDAIILAVAGLQ
RLDMSDRIHQVIPDDISLHAVGQGALGIECRTGDPEILELLKVLEDTETRDRCYAERAFL
RQLEGGCQVPIGVNTKIENNVLTLIGMVASLDGKTLIKDTIEGEPSQAESLGQTLATRLR
DAGATEILAEIFAQIQRS
>H7YX04|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni ATCC 33560|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIVSLRGNVNSRIEKLKNNKFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILKLLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>A3Y2X0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio sp. MED222|TrEMBL
MTNSAPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQLLEYRPDLIIKELRGNVGTRLGKLDDGQYDAIVLAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYSLLDGDNIWLRALVGEPDGSKMVRGEISGLRKDAEALGVTLANQLLDDGA
REILTKLYADQE
>G6ZNU4|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-21A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>E8SIS5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus pseudintermedius (strain HKU10-03)|TrEMBL
MRKLIVGSRRSQLALTQSQQFIDRLKEVDPTLDIEIKEIVTKGDQIVDRQLSKVGGKGLF
VKEIQNELFNRDIDMAIHSLKDVPSELPEGLTLGCIPDRENPFDAFISKNHIPLDELPDG
SIIGTSSLRRGAQILAKYPNLEIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDD
IVTTYLDEDLLVPAIGQGALGIECRADDDELLALLAKVHNEDVSACVTAERTFLKEMNGS
CQVPIGGYATRKNDTEIQFTGLIMSPDGKQRFEYTFSGQDPIQVGSEVSRVLKSQGADKI
IQALNEKEV
>C3LPW2|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae serotype O1 (strain M66-2)|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>E2KP84|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC4042|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>G7ENY5|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas sp. BSi20311|TrEMBL
MTEKTKLVRIATRKSALALWQAEFVKAQLEHFHDDVRVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLDGRADIAVHSMKDVPVEFPDDLELHVICEREDPRDAFVSNNFANIDA
LPQGAIVGTSSLRRQCQIRALRPDLEIRDLRGNVNTRLAKLDSGQYDAIILAAAGLIRLE
MGERIRDFIEPEVSLPANGQGAVGIECRIDDTVTKALLAPLEHSETRIRVNAERAMNRHL
EGGCQVPIGAYALVDGEQVHLRGLVGAIDGSEILRDEISGHVDDAEKLGIELAKKLLAQG
ADKILADVYRDA
>I5UY42|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4422|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>Q1LJQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)|TrEMBL
MQAPANPSSSSAAVSSSMPHKLVIASRESRLAMWQAEHVRAALQQYYPSCDVSILGMTTR
GDQILDRTLSKVGGKGLFVKELEVAMSEGRADLAVHSLKDVPMELPEGFTLTAVMEREDP
RDALVSAQFASLEEMPAGTVVGTSSLRREAALRSRFPHLVIKPLRGNLDTRLGKLDRGEY
GAIILAAAGLKRLGLGDRIRALIAPESSLPAAGQGALGIEIRADRPELAEWLAPLNHLPT
LLAVSAERAVSRRLGGSCQVPLAAHARWRDASLQLDAFVALPDGSRQVRAHATGPVATVA
DAEALGTAVAGDLLAQGADGVLAALSTDSAAGPA
>H4QQB9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC4C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E5Z959|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni DFVF1099|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>E4ZEX0|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria lactamica (strain 020-06)|TrEMBL
MIDSTPFPILVAHKDMNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRG
DRILDRTLSKVGGKGLFVKELEQALQDGRADLAVHSIKDVPMDLPEGFALAAIGERANPF
DAFVSNRYARLEEMPKGAVVGTSSLRREAQLRARYPHLAIKPLRGNVQTRLSKLDNGEYD
AIILAAAGLQRLELDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTN
ACVTAERALARALGGSCQVPLAAYCTEENGLLTLRGLVGHPDGSIVLQADAQAPAEYADA
LGRAVAKKLADDGARELIGAVLQEQV
>E8FMG0|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008282|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>F9CQ74|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O104:H4 str. 01-09591|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F6D2Z8|hydroxymethylbilane synthase|EC 2.5.1.61|Methanobacterium sp. (strain SWAN-1)|TrEMBL
MNVGTRGSSLARAQTKNIINELSKITDEEINVEIIKTTGDKIQDSQLYKIDAKGIFTKEL
DRAVLDGDVDFAVHSFKDLPTELAEGLEIVAVPQRESPLEVLVSKYSWDELPEGTSVGTS
SLRREAFCRYHKKKINIKPIRGNIDTRIKKVLSGDYDATIMAEAGLKRLGLTEHIQEIFS
REYFTPAAGQGALAVVARHDSDKKEILRRLNHTPSEQEVIAEKTVLQELGVGCQWPLGVS
ARTHGNSLDLYSILLSKEGELLSKVNLQGSVDEARKLGLKAAKLMMEDYI
>E1VBI2|hydroxymethylbilane synthase|EC 2.5.1.61|Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)|TrEMBL
MPRSRWLTCRKCTRVRGTGEGQAASLLAGGGDFPCSLRYFMMMENHVITTGSGRGAAAMR
EPVRGNQVQAMQTLRIATRKSQLAMWQAEHVRDRLMEVHPELTVELVALSTRGDQILDTP
LAKVGGKGLFVKELEEAMLDGRADIAVHSMKDVPMQFPESLGLSVILAGAEPTDAFVSNQ
YASLDELPEGARIGTSSLRRGLQMRERRPDLEVLNLRGNVQTRLGKLDNGEFDAILLATA
GLKRLGLEERITQELPPEICLPACGQGALGIECRMHDAELIGLLAPLDDPDTATRVRAER
AMNTRLEGGCQVPIAGHAVFENDGQTLWLRALVGNPEGTEVLRAEGRGSIHEPEALGIRV
AEELLDQGAGDILAEVYGAN
>A6CN69|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus sp. SG-1|TrEMBL
MRKIIVGSRRSKLALTQTNWVISQLKELDSSFEFEVKEIVTKGDQILDVTLSKVGGKGLF
VKEIEQAMLDKEIDMAVHSMKDMPAELPEGLCIGCIPEREDHRDAFISKDHVKLADLPAG
AIIGTSSLRRGAQILAQRPDLEIKWIRGNIDTRLGKLETEDYDAIILAAAGLSRMGWTSN
VVTEFLDPEVCVPAVGQGALSIECREDDEELLGLLGKFASDQVTKTVTAERTFLHKMEGG
CQVPIAGYAELLQEEDVKLTVLVASPDGKDIYKETVTGSDPVQVGEEAAALLTERGAKAL
IDKVKEELDQ
>E3DP06|hydroxymethylbilane synthase|EC 2.5.1.61|Halanaerobium praevalens (strain ATCC 33744 / DSM 2228 / GSL)|TrEMBL
MKKEYIIGTRNSSLALKQCEILKAKLSSKFPELEFKIKEISTTGDRERDKKFSEINVEGI
FIREIEYALLAEEIDLAVHSFKDLPTKLPAELEVAAVVDRANRYDVLAGAENKLAELAKG
ARLGTGSLRRKSQLLAYRPDLEIVPIRGNIETRLKKIKTHNLDGVILAAAGLERLGYKEQ
ITEYLAPEICLPAARQGAVAVEIRKEDSKLKEILKTIETEKNNLEVWTEHSFLAEMEAGC
HAPVAAEAIIENKTLTLTAAVGEIDGSRIIKKVAKTKKLDLDSVRSLAQKLAVKVKQAGA
AEIIKNLKSN
>D7VHB0|hydroxymethylbilane synthase|EC 2.5.1.61|Sphingobacterium spiritivorum ATCC 33861|TrEMBL
MNRKLIIGTRGSQLAMWQANHIKDRLAAAGIDSELKVIKTQGDIIQHLRLDKLEGKGFFT
KELEEELLSSTIDLAVHSHKDLPTVNPPGLIIAAVSERESPAELLIVLKDCVDIKKRLSL
KHNATVGTSSNRRKAQLLSLRPDLEFDDLRGNLQTRIQKLRDENYDAIILAKAGVERIDM
DLSEFYVEEIPPVELIPAPAQGVLAIQIRESDQELYEALQVIHNKEVAEVIAVERKVLNL
FDAGCHAPLGCYCRKSEGKYEAWTSVADTSDEFPDRLYIQRDSTEGMAEEIFAKFAKDRK
LPSSIFISRDIDENTYFARAMAKHNIQLDARSLIRIYPIINKLDPFILKHVDWVFFASRN
GIDHFFSLDPQLRKHTRIGVVGRGSEEALRKYDRVADFSGDDFGIHTDEIGLEFAKIANG
QTVLFPRAKDSLETIQKAMSADTKIIDMPVYETVLDENVASTTAEVLIFTSPSNVEAYFI
DNLIEPGQQIISIGKSTGAKIAEMGLPYVTPYSPDEIGLTEAVFGLKY
>H5ECC6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC10C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I5DAK6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli FRIK1996|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>H6SMI6|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodospirillum photometricum DSM 122|TrEMBL
MNPKPKLTIGTRGSPLALAQTHQVRDLLAAAHPELSEPGAIAIEVIKTTGDAILDRPLAE
IGGKGLFTKEIDEAMLSGRIDIAVHSMKDVPTYLPDGIVLPCMLEREDVRDAVIGRDHPS
IDALPLGAVVGTASLRRGAQILAKRPDLKVVSFRGNVQTRLAKLARGEVDATLLAKAGLN
RLGMADKITSLLEVDQMLPAVAQGAVGVTCRADDEAAHRWLAPLNHAETFLCVTVERAFL
AKLDGSCRTPIGGLARVSDFGTDQARVFFRGMIISPDGKVIHQTTREGSVAEAVALGDDA
GAELLAKAGPNFFTGAHA
>C6RSH2|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter radioresistens SK82|TrEMBL
MMMTLKIATRKSPLALWQAEHIRACLQELHPGLTVELVTFVTQGDKILDTPLAKIGGKGL
FVKELEAALLDGRADLAVHSMKDVPMHLPTGLSLPVICEREDPCDAFVSNRFEGFEQLPK
GATVGTSSLRRKTQILKARPDLNILDLRGNVGTRLSKLDAGEYDAIILASAGLKRLGLSE
RIKHTLSPELSLPAVGQGALGLECRTDDQAILDLISPLQHEQTSICVRAERAFNSHLEGG
CQVPIAAYATLENGQLQLEGRVGSVDGLILLSSQVSGQPEHAEQLGIELAENLLSQGAGE
LLKALYK
>F8IDJ7|hydroxymethylbilane synthase|EC 2.5.1.61|Alicyclobacillus acidocaldarius (strain Tc-4-1)|TrEMBL
MELRTLRVATRRSALALTQTNYVVDLLRRVAPGVEFELVPIRTRGDEIVDRALSEVGGKG
LFVADIEEALATGQADLAVHSLKDVPFELREGLTIGAVPPREDPRDALISRTGQGLFDLP
SGARVGTSSLRRQAALRRLRPDLCVDTLRGNVDTRLRRLEEGQFDAIVLAASGLHRLGLA
GKITEYLPVDRFVPAVGQGALAVECRTEDDEVMRHLAAISDPDATRAVEAERTFLARLEG
SCQVPIGAYAESVGRGLRLIAFVADPSGNHHLQLERTGDDAGALGVAVAEEMLRQGAEAW
LRPA
>F8IBM6|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfobacillus acidophilus (strain TPY)|TrEMBL
MANLSIGTRGSELAVRQTDLIVSRLESQEHHVTVVRVETHGDRVLDRALNQLGNQGVFTT
ELEQRLVAGTIDLAVHSLKDLPTQLAPGLAIGAYALPEDRRDVLLAGDYTLATLPPGARV
GTSSLRRTAFLRSLRPDLEVVPVRGNLQTRLRKWQELGLDGLLLAAAGVHRLGWQDKISE
YLDPFAMVPAPGQGILAVEMVADRQDIAKILAPLDDPAARVLAQAERGVLARLGGGCQMP
LGAYATWDGETVYLLGQAADPAGTRLARAEARGTASDTDRLAEEVADELRRQGALAWIQP
>Q5L6E5|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydophila abortus (strain S26/3)|TrEMBL
MLSDCYNNPFLSDFCLGKRPLRIASRKSILAQAQVHECVRLLRSWFPKLWIQIHTISTRG
DKDKTTPIRLVENSQFFTDTVDKLVIRGNCHLAVHSAKDLPDPPATPVVAITKGLDPSDL
LVYAERYLWQRFPKVPRLGSSSSRRGETLKMLFPTGRILDIRGTIEERLEQLENGKYDAI
VVAKAAVLRLHLQLPYTKVLPPPYHPLQGRLAITAGKDIEAWKTFLLPLNTATTNQETLL
SSNLICYDD
>C8T0I7|hydroxymethylbilane synthase|EC 2.5.1.61|Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884|TrEMBL
MTVTSMLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLKVELVPMVTRGDVILDTPLAK
VGGKGLFVKELELAMLEGRADIAVHSMKDVPVEFPECLGLVTICERDDPRDAFVSNRYAS
IDELPAGSVVGTSSLRRQCQLAATRPDLAIRSLRGNVGTRLSKLDNGEYDAIILAAAGLK
RLQLEARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTRGLLAPLNHTETAVRVRAERAMN
TRLEGGCQVPIGSYAELKDGELWLRALVGAPDGSQLVRGERRGPAEQAEALGISLAEELL
DNGAREILAAVYDGEAPR
>E8MDR8|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio sinaloensis DSM 21326|TrEMBL
MTQSSPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPSGLGLVTICEREDPRDAFVSNTYNSIDEL
PQGAVVGTCSLRRQCQLKEYRPDLIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHQDTADRVLCERAMNLTLE
GGCQVPIGSYALLEGDDIWLRALVGEPDGSQIVRGEIKGPRSESEALGIKLANQLLDEGA
REILTKLYADHE
>G8LAX5|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia slovaca (strain 13-B)|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>I5MVR4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA42|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D1BNZ5|hydroxymethylbilane synthase|EC 2.5.1.61|Veillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3)|TrEMBL
MRDHIRIGTRKSALALWQAEHISAELQRLYPNITVELVHFNTKGDRILEKPLAQVGGKGL
FTAELEEAMHAGDIDIAVHSLKDMPTELPEGLTLGAISAREVPYDALVSPVYKTLDKLPQ
GARVGTSSLRRQAQLLHVRPDLKVEVIRGNVQTRLSKIETEKLDGVILAQAGLKRLGLED
QITQVFKADEMIPAVGQGALAIECRADDTEMLDMLDPINDEATRYAVEGERSFLRQLNGG
CQVPMGVHGTINKGQLTLKAMIASLDGKTVYEGEISGPAKKGEILGKNLAKALYEEGGKR
IVDALIEEGIIK
>C7MKX4|hydroxymethylbilane synthase|EC 2.5.1.61|Cryptobacterium curtum (strain ATCC 700683 / DSM 15641 / 12-3)|TrEMBL
MTDKTITIGTRGSKLALWQAEKVRALIQATFPEVHCAVKVIRTKGDKILDVALSKIGDKG
LFTKELERCLLEGEVDVCVHSMKDMPTVLPKGLFIAGVTERAYPNDVIVASAKGLTLSDL
PAGARVATGSLRRVAQLARLRPDVTACEIRGNIDTRIGRVLAGEFDAAILAAAGLYRLGL
EEQISSLIPTEEMIPAVGQGAIALEARADDREVAHLCTAISHQPTLRAVEAERYIMRALE
GGCQVPMGAYATESEDEQGRRMIHIDAFVATLDGTRFLRAQASTPVDQAIEAAGKIVDDL
VSQGATEILEALR
>Q5HBG1|hydroxymethylbilane synthase|EC 2.5.1.61|Ehrlichia ruminantium (strain Welgevonden)|TrEMBL
MNSMNVYVGTRGSILAIAQAMEVKKLLYNYFPDINVQIVHIVTSGDINDKISLSEIGGKG
LFLKELEEALLTGTIDLAVHSMKDVPAFYCDSLVIPCILKRSSPYDVFISSKYQSLRSLP
DNAVIGTSSIRRKVQLMRLLSSVQVVPIRGNVDTRILKLEAGQYDGIILAKAGLMRINKT
HVIKEVLDPQVMLSAVGQGAIGIQCRANDYKMIDMIKILNCKKSYISVAAERSFMKTVNG
SCDTPLAALAKYVNSDTLYMSCMLSNEEKTVFSDCYFNECDAEISGINMGNDLMDQLNN
>F9L462|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus capitis VCU116|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKKVDPDLDIEIKEIVTKGDQIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSIIPEGLTLGCIPDREVPFDAYISKNHTPLSELTEG
SIVGTSSLRRGAQILSKYPHLEIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDD
IVTTYLDKDVLLPAIGQGALGIECRSDDKELLELLKKVHNQDVAQCVTAERTFLSEMDGS
CQVPIGGYATIDGDKQIEFTGLIMTPDGKERYEHTAKGLDPVELGQEVSRVLKEQGAYEI
IRKLNEENN
>H1SPE3|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21252|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSELPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>B1QT88|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium butyricum 5521|TrEMBL
MDKLILATRKSRLAQVQTEIVMDSLKNKINKESEKLLIVTEGDRKLDVSLNKIGGKGLFV
KDIECALLEGSADAAVHSMKDVPYELSNEFEITAIIEREDIRDVLISKDGISFSKLRYGA
KIGTSSIRRAAQLKLLRSDIEVVPIRGNVQTRLAKMESENLDGIILAAAGIHRLKLDSII
TEYFDPKEFIPAVSQGAIGIECVKNSENSKYFKMLDNSEARITVEAERSFMRELKGDCHS
LIGAYSEVTGDELYMIGIYDLNGVIVRKDIKGKKSNHLEVGRKLAEKILNEK
>H4Q8V6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC4B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D5VSM4|hydroxymethylbilane synthase|EC 2.5.1.61|Methanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME)|TrEMBL
MIIGSRGSKLALYQANLVLKKLKSLGIDGEVKIIKTRGDQIKDRALHSIGIGVFTKELDL
SLLNHEIDIAVHSLKDIPTVWNSRLSYVVLERDYPNDLLIANKEDIKVIGTSSLRRRAFL
KELYRDAEFKLLRGNVDTRLRKLKDNEYDAIVLSEAGVRRLNIDLSEFLVYKLPILPAPG
QGVIAVAYRKEDEKIKNILEKINDKKTFLETTAERKALNELGCGCHVPFGAFAKYEGKRL
MLKVAVANKDRVIKKESSICCEVDEIEKAEKLGESLGRELRRCIREL
>H8N5A4|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia prowazekii str. Katsinyian|TrEMBL
MINSIRIGTRNSTLALIQTNLVIEQIKQIFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGKIPVELVIAAVLEREDPRDVLVCLNYQSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDAIILSYAGLKRLNVFN
QKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPERAFLEYLDA
NCSTPIAAYAQYLDAYNIQIDFMLGNLDCTKIIFQTEITNIKTSKICGIKAAKMMLAQQ
>E8F012|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. IA_2009159199|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I2ZK73|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli B41|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>E1L4F0|hydroxymethylbilane synthase|EC 2.5.1.61|Veillonella atypica ACS-049-V-Sch6|TrEMBL
MRNHIRIGTRKSALALWQSEYVKSELQRLYPGVTVELVHFNTKGDRILNKPLAEVGGKGL
FTAELEAAMHAGDIDIAVHSLKDMPTELPDGLTLGAISKREVPFDALVSPKYKTLDQLPE
GARIGTSSLRRQAQLLHRRPDLQIEVIRGNVQTRLGKIETEGLDGVVLAQAGLKRLGLDD
RITQVFTADEMIPAVGQGALAIECRSDDTEMLEILSKIDDEPTRLAVEGERSFLNQLNGG
CQVPMGVYGTVEKGQLNLKALIASLDGKTVYEGELSGPAKKGVMLGKNLAKALYEEGGKH
IVEALVKEGIIK
>D8MKT4|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia billingiae (strain Eb661)|TrEMBL
MLDKILRIATRQSPLALWQAHYVQQRLMACHPGLRVELVPMVTKGDVILDTPLAKVGGKG
LFVKELEQAMLEDRADIAVHSMKDVPIAFPEGLGLVTICEREDPLDAFVSNQYDSVDALP
QGAVVGTSSLRRQCQLSARRPDLIIRSLRGNVGTRLGKLDAGEYDAIILAVAGLKRLGLG
DRIRYAMPAEESLPAVGQGAVGIECRLDDAQAIALLSALNDDDTAIRVKAERAMNTRLEG
GCQVPIGSFALLQGDELWLRGLVGSPDGTAMIRGERRGPRADAEKMGISLAEELLNNGAR
EILAEVYQGNPPA
>I3AA88|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 900105|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>D6CUE3|hydroxymethylbilane synthase|EC 2.5.1.61|Thiomonas sp. (strain 3As)|TrEMBL
MTSTFTPPPSLVIATRESRLALWQAEHVRDLLKGLYPQCDVRIFGMTTQGDQILDKSLAK
IGGKGLFVKELEVAMEQGHADLAVHSLKDVPMVLPTGFALTAVMEREDPRDAWVSPHYAN
LADLPAGAVVGTSSLRRESQLRARYPHLKVQALRGNLDTRLRKLDEGQYAGILLAAAGLK
RLGLGERVRAVIEPEDMLPAVGQAALGIEIRADRPDLAQALAALNHPPTALCTHAERAVS
RGLGGSCTTPMGAYATLEGEAMHLRAVLGLPDGSQALHAQQRGRVTDLAQAEALGQQVAR
QLREQGADALLAQLGSH
>A9KSC4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg)|TrEMBL
MKKQKIVVGSRDSKLAVMQTELIMHEINRNNPEIELELVTLKTTGDLILDQSLDKIGGKG
LFVKELDLALLDGRIDIAVHSLKDMPMEENKELPIVALPKRGDARDVLVLPKGCEFIEYE
DMNLYYQNIGSSSARRKLQIQKLLPSAGTSGVRGNVITRLDKLDRGEYTSLILAAAGLQR
VGLPHRISHYFSVEEMIPAAGQGILSIQARRDLNVDFLENIKDANTTYASLAERSFVRTL
DGGCSSPIAAYAAVEGEELKLVGLYYNEKTTEHRVATVVDHKERAERVGEQLALRLRGEI
G
>D7WQ85|hydroxymethylbilane synthase|EC 2.5.1.61|Lysinibacillus fusiformis ZC1|TrEMBL
MRKIIVGSRRSKLALTQTNWFINELKAAGVPFEFEVKEIVTKGDQILDVQLSKVGGKGLF
VKEIEQALYDKEIDFAVHSMKDMPAVLPDGLVIGCIPPREDARDAFISKGHVKFADLPAG
AVVGTSSLRRSAQLLTVRPDIEIKWIRGNVDTRLAKLETEEYDAIILAAAGLKRLGWSDD
VVTEFLPVEQCLPAVAQGSLGIECRADDAELLAELGKLTDSFTWQEAHAERAFLAAMDGG
CQVPIAGYATSIGEEITLTGLVAAPDASVVFKETVVGTDAQKIGEELAAILTEQGAFDLI
QRVKAEQDAE
>I6DWN4|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella sonnei 3226-85|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAKQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D0KRN2|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus solfataricus (strain 98/2)|TrEMBL
MKILIAARGSKLSRVQVDMVGEKLRKIGIEYDVIDIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADVAVHSMKDILSEINPELEIFAVIERDPPYDILIAEKNLHKLDPNTTIGTS
SIRRKNFIKYIRPEINTKDIRGNVDTRIRKYLSKEYDGLILAEASIKRLNISISYHRLNV
YDFTPEANQGIIVVLGRKKDEKVKEVFKEITHKDTLDEALAERATISVVGGGCHSPIGVL
FRKEGKEFYGIASYSDGKKKITVSISKAGDPYTIGSELGLLLKKEMKNEGIIP
>C2GS24|hydroxymethylbilane synthase|EC 2.5.1.61|Lactobacillus reuteri CF48-3A|TrEMBL
MTDKVIVGSRKSKLAMAQTKLVIASLKELFPTTQFEIKNVITEGDRNQQASLAKIGGKGV
FVKEIEEELKNCTIDFAVHSLKDVMPVLPDELTLGAFPKRVSPFDCLVSRQEFTSLDALP
HGARIGTNSLRRQGQLLNVRPDLKIIPIRGNIDTRLKKIDTENLAGVVLAEAGLDRLSID
LSSYHQLSLKDIIVPAVGQGCLAIECRKADERVRKMLDQINDPQSAKCIHIEREFMRELG
GSCNFPIGGHAYLQDQQIVFDGLIASPNGEHLIKEVAVPANKPGVGKVVADQLLAKDNFG
IIEGD
>A9EI54|hydroxymethylbilane synthase|EC 2.5.1.61|Phaeobacter gallaeciensis 2.10|TrEMBL
MTQIDLPSPASPLKIGTRGSPLALAQAHETRARLVAAFDLPQDAFEIVVIKTSGDNQALI
AADKPLKELGGKGLFTKEIEEDLLSGAIDIAVHSMKDMPVAQPAGLLLDTYLPREDVRDA
FVSPDVTAITDLRAGAVVGTSSLRRRAQLLHRRPDLQVVEFRGNVQTRLTKLRDGVAECT
FLAMAGLNRLGADQVPATPIPPEDMLPAVAQGAIGIERRADDSRTGDMLAALHDRETGER
LAAERAFLAALDGSCETPIAGLATLEGRTLRLRGEVLRPDGSEAISDEQTCPVEDGAELG
REMATKLLAQAGAGFFDWKR
>H4URI6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC6A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A0RXB2|hydroxymethylbilane synthase|EC 2.5.1.61|Cenarchaeum symbiosum (strain A)|TrEMBL
MTVYTVGTRGSRLSLAQTGHVLDALKEANPEDEYKVRRIKTQGDTDDRPLFAIDQKGIFE
KEIDRAVSEGGADFAVHSLKDVPTELAPGLVLACVPRRAAANDVLVSPGGSGLGSLPRGA
TVGTSSLRRAVQVGRSRSDLHVKPVRGNIETRIAKVGAGYDAVVLAEAGISRLGLDVKYA
ALPEESFAPSPGQGSLALVARSGDAGTISMLNRIEDAASRAEAEAERALSERIGSGCRFP
VGALARSAGELLTIRAEAFSVDGSRSVSVQASGPRGSPRKVGESAGNEMLERGAGDLALN
WREKVDEWNRS
>C6X7P1|hydroxymethylbilane synthase|EC 2.5.1.61|Methylovorus sp. (strain SIP3-4)|TrEMBL
MTSTSPISIPEKLVIASRESALAMWQARHIQARLQALYPSTQVEILGMTTTGDQILDSPL
ARIGGKGLFVKELEQALADGRADLAVHSMKDVPMHLPEGFAMAAIGEREDPRDAFVSNDY
PSLEALPAGSIVGTSSLRRQSQLQARFPHLVIESLRGNLQTRLRKLDEGQYAAIILAAAG
LIRLGLGNRIAQTIAPEDSIPAVGQGALGIEINAARTDLLTVLAPLNHADTAACVEAERG
MSRALAGSCTVPLGAYATKQGENITIHGFVASVDGKQMLRAEATGNAAQPELLGQQLAQS
LIARGADKILQALAEQSAHG
>B5EZ60|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella agona (strain SL483)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKY
HSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAG
LKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEE
LLENGARAILTEVYNGETPA
>I3ECS8|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus methanolicus MGA3|TrEMBL
MRKIIVGSRRSKLALTQTNWVIEQLKKLDPSFDFEVKEIVTKGDRILDVTLSKVGGKGLF
VKEIEQAMLNKEIDMAVHSMKDMPAILPEGLMIGCIPEREDHRDALISKNHIPLKELKPG
ARIGTSSLRRGAQLLAKRPDLEIKWIRGNIDTRLAKLETEEYDAIILAAAGLSRMGWTSD
FVTEFLDTDVCLPAVGQGALAIECRSDDHELLKLFEKFTSEKTSRAVRAERAFLQKMEGG
CQVPIAGYAFINDNDEIVLTGLVASPDGKEIYKEQAAGRNAEELGISVADKLINKGAKDL
IEKVKQEQDRT
>Q3R7S7|hydroxymethylbilane synthase|EC 2.5.1.61|Xylella fastidiosa subsp. sandyi Ann-1|TrEMBL
MPLLRIATRKSLLAMWQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIG
ARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQR
MTARLAPPEWLPAPGQGAIAVESLTEDARIATLLAGLDDLPTRQCVVAERTMNRALHGSC
HVPVGAYASYEVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAEL
LAATA
>E2SF03|hydroxymethylbilane synthase|EC 2.5.1.61|Aeromicrobium marinum DSM 15272|TrEMBL
MTVQLPALRLGTRASVLARTQSGHVADRITEVSGRAVELVTISTEGDRSTGPLAEMGGQG
VFVAALREAVAAGHVDLAVHSLKDLPTAPDPRLALAAVPPREDVRDVVVARDGLTLGELP
QGARIGTGSPRREAQINALGLGVEIVPIRGNVDTRIGKVASGEVDAVVLARAGLLRLGRA
DEATEVLDPIQVLPAPGQGALAVECRAGDDELIGLLAALDDADTRAAVTAERSLLAALEA
GCSAPVGALAEVAWGDDGDELWIRAVVADPSGSPTIRLSATGLPAEAAAVGERLAAEMLA
DGADRIMAPVP
>E2SF03|hydroxymethylbilane synthase|EC 2.5.1.61|Aeromicrobium marinum DSM 15272|TrEMBL
MTVQLPALRLGTRASVLARTQSGHVADRITEVSGRAVELVTISTEGDRSTGPLAEMGGQG
VFVAALREAVAAGHVDLAVHSLKDLPTAPDPRLALAAVPPREDVRDVVVARDGLTLGELP
QGARIGTGSPRREAQINALGLGVEIVPIRGNVDTRIGKVASGEVDAVVLARAGLLRLGRA
DEATEVLDPIQVLPAPGQGALAVECRAGDDELIGLLAALDDADTRAAVTAERSLLAALEA
GCSAPVGALAEVAWGDDGDELWIRAVVADPSGSPTIRLSATGLPAEAAAVGERLAAEMLA
DGADRIMAPVP
>E8GKY8|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008285|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H0G358|hydroxymethylbilane synthase|EC 2.5.1.61|Sinorhizobium meliloti CCNWSX0020|TrEMBL
MQTKPFRIGTRGSPLAMAQTHETRDRLAAAHGLPPEMFEIVILSTKGDRITDRSLAEIGG
KGLFTEELEQQLLSGDLDFAVHSSKDMPTKLPEGLFLSAFLPREDIRDAFVGRSAKRLVD
LPQGATVGSSSLRRQALIRRLRPDIDVITYRGQVETRLRKLAEGQVDGTLLAYAGLKRLG
MEHVPTELLDPEEFPPAPAQGAICVEARIGDDRINTLLAAIDDPRTHEAVSCERGFLATL
DGSCRTPIAGYAQSDGTHIRFAGMILTPDGATSHQIEIDGRAADAERLGQEAGERIRTKA
GPGFFSSWS
>F8Z5D3|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-48A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>D2N801|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain MRSA ST398 / isolate S0385)|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDDELLSLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>C8WIZ2|hydroxymethylbilane synthase|EC 2.5.1.61|Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255)|TrEMBL
MHRMRIGTRGSKLALWQAHHVADLLRAASPGMDVSVEVVKTKGDRILGVALSKIGDKGLF
TKELEQALFDGRVDVCVHSMKDVPTALPEGLALAGCLIRADARDVLVAASGTTFAGLPAG
SRVGTGALRRLSQLRAVRDDLDYVEVRGNLDTRIAKVRDGALDAVVLAAAGIERMGWSAE
VAEAFSVDTVVPAVGQGAIGLEVRADDERTARACAQVRCAATDACVAAERHVMRALDGGC
QVPIGAYARYEEGLLVLDAFVGSLDGSHVLRSRLSAASQPPNDTDAVEAAVREARALAQR
AVEEFEAQGARAVLDAVRAAGDERPLA
>I4U5I5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 75|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F0T109|hydroxymethylbilane synthase|EC 2.5.1.61|Syntrophobotulus glycolicus (strain DSM 8271 / FlGlyR)|TrEMBL
MKTIRIGTRESKLAIWQAEWVKDSLTSIYPGIDCVLVPKKTKGDKIPDIPLPKIGDKGFF
TEELEQALLTGEIDLAVHSLKDLPVELPQGLSIAAYGERHDPRDVFFGKEGLPLAELPAG
SMIGTSSLRRQCQLKYQRADLNFCDLRGNLDTRWDKLQNSRDMAGIVLAAAGALRLGWQD
RITEFLAEDVVLPAVGQGIIAIETASHRTEIRQILQPLNHRPSELAGRAERSFLRSLGGG
CQTPIAALAKVQEDRIQVTGMVAGMDGKNILKVTAEGFDPEQTGADAAAQIKCLGANNLL
KEIQG
>C6C7C7|hydroxymethylbilane synthase|EC 2.5.1.61|Dickeya dadantii (strain Ech703)|TrEMBL
MVDNILRIATRQSPLALWQAHYVQQRLQACHPGLRVELVPMVTRGDVLLDTPLAKVGGKG
LFVKELELALLEDRADIAVHSMKDVPVEFPAQLGLVTICERDDPRDAFVSNRYANLDALP
PGAVVGTSSLRRQCQLRARRPDLVIRDLRGNVGTRLGKLDNGDYDAIILAVAGLNRLGLE
GRIRAALSPEQSLPAVGQGAVGVECRLDDTRTRALLAPLNHDDTAARVLAERAMNTRLEG
GCQVPIGSYAELQGDAIWLRALVGSPDGSRIIRGERTGRRQDAEQLGISLADELLAAGAR
EILQAVYYGGANS
>E6LWK0|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus curtisii ATCC 51333|TrEMBL
MQTIGSTERPLVIGTRASALALTQTRAVASDLEQRGLHVQVQTFTTEGDINRASLASLGG
VGVFAAALRVALLEGHCDLVVHSLKDLPTVPVDGLVVAATPTREDPGDVLVARDSLSLAD
LPAGSRLGTGSPRRARQIAVARPDIELVDIRGNVPTRVGRVKGLAAVAEHAGLPSGKAAE
DLDGVVLARAGLRRLGMDDAITDSLEGTVIPAGGQGALALETRSELLDSDEGRNFAQILK
FVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGIVTWDKHTEAPSGRLELTARVIGNQGE
VLEVNGETTVLLGAEAAQRDFALAAAEQLGVDLAGELLEAGAATIADLKVAKSASTQTDA
NQTICNEKELWGE
>E6LWK0|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus curtisii ATCC 51333|TrEMBL
MQTIGSTERPLVIGTRASALALTQTRAVASDLEQRGLHVQVQTFTTEGDINRASLASLGG
VGVFAAALRVALLEGHCDLVVHSLKDLPTVPVDGLVVAATPTREDPGDVLVARDSLSLAD
LPAGSRLGTGSPRRARQIAVARPDIELVDIRGNVPTRVGRVKGLAAVAEHAGLPSGKAAE
DLDGVVLARAGLRRLGMDDAITDSLEGTVIPAGGQGALALETRSELLDSDEGRNFAQILK
FVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGIVTWDKHTEAPSGRLELTARVIGNQGE
VLEVNGETTVLLGAEAAQRDFALAAAEQLGVDLAGELLEAGAATIADLKVAKSASTQTDA
NQTICNEKELWGE
>I3DHN1|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus parahaemolyticus HK385|TrEMBL
MKDTLRIATRQSPLALWQANFVKAELEKHFPELSVELVTMVTKGDIILDTPLAKIGGKGL
FVKELELALLENRADIAVHSMKDVPMSFPEGLGLAVICEREDPRDAFVSNHYANLDELPA
GAVVGTSSLRRQCQLMAKYPHLTVKSLRGNVGTRLSKLDNGEYDAIILASAGLIRLGMPE
RIKSFISVEQSLPAAGQGAVGIETRINDERILNYLAKLNHETTACCVKAERAMNTRLQGG
CQVPIGGFATIKNGEITLNALVGALDGSSIIRATGKAPVSEAELLGVKIAEQLLAQGADK
ILAEIYAE
>C7M2H5|hydroxymethylbilane synthase|EC 2.5.1.61|Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)|TrEMBL
MAPVRIATRRSALARWQASLVGERLGRYELVEVHTAGDRDQASSLAEIGGQGVFVKEVQA
AVVRGEADIAVHSAKDLPTAAGPLLLAAVLERADARDAIVGARLEELAIGARVGTSAPRR
AAQLRLLRPDLEVVSIRGNIATRLGRVGELDAIVMAVAALERLGLEEPPWWPLPEEVLCP
QAGQGAIAVECAPDADGLIERLRSLDDDRSRREIEAERAVLAAFGTGCALPLGARAHADG
SSLRLRAVAVDPDGTRQLEVEREGVDPATLGATVAEVLRRLGADALVGARP
>F0FRJ5|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK678|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKKLHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRQLLATVQDEKTAAEVAVERVVLAQM
NADCTFPIAAFAQKNGQDYQLEAMLAKEDGQCVFVSLKGQDGQQLAEQAVRQLADKGAVG
MPWLKK
>C8W5F1|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM B-1644)|TrEMBL
MREIVVGTRDSQLALWQANWVVDRLRERNPGYSFRIQGIKTHGDNILDVALAKIGDKGLF
TKELEVALLSDEIDLAVHSMKDLPTDLPGGLAVGAVCEREYPGDVLVSSQGYVLDKLPEG
AVIGTSSLRRTAQLLHYRQDLRIVNIRGNLNTRLRKMDEEKLDGVVLAYAGIQRLGLKDR
ITERIPMEICLPAVGQGSIGIEIRHLDEEIMDIVETIEHRPSRIAVSAERNFLKRLEGGC
QVPIGAYGLVIGNEIKFEGLIASLDGKHLVRDVIAGPVNEAAKIGVKLAESLLKKGGREI
LRAVRQENC
>I5JCM4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA25|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F9AVM6|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HE48|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDHIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>G8XBB3|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacterium columnare (strain ATCC 49512 / CIP 103533 / TG 44/87)|TrEMBL
MKEKKIKIGTRDSELALWQAHTVKKQLNDLGYQTEIIAVKSQGDIILDKPLYELGITGIF
TKTLDAAMISGQVDIAVHSMKDVPTALPQGIVQAAVLERANSVDILVHKGTTDFLNTTTT
IATGSLRRQAQWLHKYPQHKTVDLRGNVNTRLQKLKDNDWGGAIFASAGLERLNLKPETT
LSLDWMIPAPAQGAMMVVAMAEDTFALEALSELNHIETEICTYIERQFLRTLEGGCTAPI
GALATYNEKTDQIHFKGALFSIDGQQKIAIERSFEVSEWKKLGLNCAKELLENGGTELMS
VIKEQLKK
>I6CD16|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri K-315|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDARTRERLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>D5UT18|hydroxymethylbilane synthase|EC 2.5.1.61|Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040)|TrEMBL
MSDSDSTADTLPVPLRIGTRGSLLATTQAGTVRDALIAAGHPAELVIVTTPGDLSSDPVE
KIGVGVFTSALRDALANGEVDVAVHSYKDLPTAPDDRLVLAAVPPREDSRDALVARDGMV
LGELPAGSVVGTSSPRRATQLTALGLGLEIRPLRGNLDSRLRKVADGELDAIVVALAGLK
RIGRHDEVTEALDPVQMLPAPAQGALAVECRRGDADLQSVLSELDDHWTRAAVTAERALL
AELEAGCTAPVGAIAEVVESLDDDGRIFEELSLRGIALAADGSDSVKASAVGPVGEAGAL
GTALARELLDLGARDLLA
>H2HFS4|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain HC02)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>B1M3A7|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831)|TrEMBL
MLNRPLRIGTRGSPMALAQTGMVRDRIVAANPGLETELVVVTTVADKILDRPLSEIGGKG
LFTKELEQALFAGEVDVAVHSMKDVETWLPDGLTIACILERDDPRDAFLSPHADGLAGLA
AGARVGTSSLRRGAQVLMRRPDLRVVPLRGNANTRMRKLEAGECDATLLALAGLQRLGLE
SMARSVLSVEEMLPAVAQGALGIECRADDAVIRDLLAPIACERTTVAVSAERALLAELDG
SCRTPIAALAQIDGDSLRIDGLLFLPDGSRHWAASRQGLVAEAERIGREAGAALKAAAGD
TYTRHLQ
>I6KDJ4|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis PY-101|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>H4R959|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC4E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A8IJ75|hydroxymethylbilane synthase|EC 2.5.1.61|Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)|TrEMBL
MPDPNAPFAPRLAIGTRGSPLALWQAHAVRDALAAALARPVESISITVIRTSGDSIQDRA
LSEAGGKGLFTKEIEEQLLDGRIDLAVHSAKDMATALPDGLFLSGFLPRADVRDALILRE
GKSLADLPAGARIGTASLRREAQLRRLRPDLDVSLLRGNVHTRLAKVREGTFDGTLLALA
GLTRLGLAHEASAVLDTDAFLPAVGQGAVAIESRVGDEATNGAIAAIACRATGIALAAER
ALLTALDGSCRTPIGGLATVEGDMVRLRGLILSPDGRDAAEADETAPVSDAARLGADMGA
RLRATAPARALGL
>H1XLP0|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas axonopodis pv. punicae str. LMG 859|TrEMBL
MTTLRIATRKSPLALWQSEHVADALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDEPFVLPAILERGDPADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEAR
ISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAAFARWEGQDLFLQGMVGSASDGRLIHADAHGSADDTEALGRRVAQGLFDKGAAQL
LAEL
>I5TMS3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW14313|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B5S1K9|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia solanacearum MolK2|TrEMBL
MWQAEYVRAALQKYYPACDVSILGMTTRGDQILDRSLAKVGGKGLFVKELEVALAEGRAD
LAVHSLKDVPMELPPGFALPAILEREDPRDAFVSNQYADLAALPAGAVVGTSSLRREASL
RARFPHLVIQPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLSERIRAVIASDVSLPAA
GQGALGIETRADRTDVQAWLAPLHHLPTALAVTAERAVSRRLGGSCQVPLAAFAHWTDAG
ALRLRAFVASQDGRRKLAAEGEATPATLAEAEALGARVAQQMLDGGAWDILATLGADAPP
AT
>H8BG01|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 87330|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>E6UPR0|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium thermocellum (strain DSM 1313 / LMG 6656 / LQ8)|TrEMBL
MKIRVGSRESKLAVRQAQIVIDSIKKYNPDIEIELVTMKTTGDKILDKTIDKIGGKGLFV
KELDRALLDGKVDITVHSFKDMPMDIDDRLPIVAVSKREDPRDVLVLPKGKNEIDFNGPI
GCSSSRRKIQIEKIYPGCTVEPIRGNVLTRLEKLDKGEYSAIALAYAGLKRLGLEERIWR
VFSTDEIVPAACQGIIAVQARKDFDASILANFHDKDSWDVSVAERSFIKALNGGCSSPSA
AYGVIQGEKIVLTGFYVDKNGKIYKMTKTGDRNQGEALGYSLAMEMLKGADA
>A3STB9|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfitobacter sp. NAS-14.1|TrEMBL
MTVNLPTPENPMRIGTRGSPLAMAQAYETRARLAAAFEIPQAAFEIVVIKVTGDVIQDRP
LKDIGGKGLFTREIEEDLLAGKIDIAVHSMKDMPTIQPGGLLLDTYLPREDPRDAFVAPT
LSALDQLAESAVVGTSSLRRRAQLLHQRPDLQVVEFRGNVQTRLKKLADGVAECTFLAVA
GLNRLGMQHVPATPIDDTLMLPAVAQGAIGIERRAGDLDTEAMLAAIHDTPTGQRLAAER
AFLLTLDGSCETPIAGLATLDGDTLHLRGQVLRPDGSEAIAGDRSGPIAQGGQMGVDLAQ
DLLAQAGPGFFDWHVKG
>F5NMQ5|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri K-272|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>O69107|hydroxymethylbilane synthase|EC 2.5.1.61|Lysinibacillus sphaericus|TrEMBL
MLRKIIVGSRRSKLALTQTNWFINELKAAGVPFEFEVKEIVTKGDQILDVQLSKVGGKGL
FVKEIEQALFDKEIDFAVHSMKDMPAVLPEGLVIGCIPPREDARDAFIS
>E8QKH5|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain Gambia94/24)|TrEMBL
MGKLVIGSRGSELALWQANHIKERLKKECSMESEIQIVKTTGDKILDAPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKFKRKDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLNVQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDEVKIRAVLGLPNGKEVITKEKQGDKTKAFDLIQELLEEFLQSGAKEIL
EKAQLF
>Q1NU29|hydroxymethylbilane synthase|EC 2.5.1.61|delta proteobacterium MLMS-1|TrEMBL
MWNNIRIGTRASMLALAQANWIKGRIEAQHPQCRVELVKIITKGDKIVDVPLAKVGGKGL
FVKEIEEAMLRGEVDIAVHSMKDVPAELPQGLHIGIITQRENPFDAFVSNLYQNIEALPT
GARVGTSSLRRKSQLAALRPDLTIEDLRGNLDTRLRKLDEGQYDGIILAAAGLNRLDLAH
RATFYFQAEQMLPAVAQGAVGIELRRADADLLEMLSFMDHRATTLAVKAERAYLKRLEGG
CQVPLAGFATLDGDRLQLDTLVAAIDGSRLLKVSKSGPAEEAEEIGLAAAEELLAAGGRE
ILEEVYGTSLS
>E5B0K2|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia amylovora ATCC BAA-2158|TrEMBL
MSDKILRIATRKSPLALWQAKYVQQRLIDCHPRLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELENAMLSGHADIAVHSMKDVPVAFPQGLGLVAICERDDPHDAFVSNHYASVDSLP
AGAIVGTSSLRRQCQLSARRPDLVIHSLRGNVGTRLGKLDAGEYDAIILAVAGLKRLGLS
GRIRQVMPAEESLPAVGQGAVGIECRLDDMRTIGLLAALNHDDTACRVSAERAMNTRLEG
GCQVPIGSYALLEGDRLWLRGLVGSPDGSQMVRGERRGSRADAEKMGISLAEELLDNGAR
DILAAVYQGNPPA
>B1ZBS8|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)|TrEMBL
MSLSRPLRIGTRGSPMALAQTGMVRDRIVAANPGLETEIVVVSTVADRVLDRPLSEIGGK
GLFTKELEQALFADTIDVAVHSMKDVETWLPDGLAIACILERDDPRDAFLSAGTANGLAD
LPSGARVGTSSLRRGAQVLMHRPDLMIVPLRGNANTRMRKLEAGECDATLLALAGLQRLG
MEDVARSVLPVEEMLPAVAQGALGIECRAGDDAIRALLAPVACATTTTALDAERGLLAEL
DGSCRTPIAALAQVNGDRIALDGLLFLPDGSRHWAVHREGPAAEADAIGRDAGAELKRSA
GDVYFAHLK
>Q897K7|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium tetani (strain Massachusetts / E88)|TrEMBL
MAVHSMKDVPYEVPSMFYIGAIPRREDVRDAFVSRDGTKFMELPSGSKIGTSSRRRSSQI
KILRPDVEVVPIRGNVQTRLRKIEEMNLAGTILAVAGLKRLNMEEVITDYFSPEEMVPAI
GQGALGIEIKKYEDVIDYIKGIDHEETRICVEGERSFMEALKGDCHSTIGAHAIVENDLM
YMTGIFEVNGKIVKKDIEGKKENYKQLGKTLADRIMKA
>A0ZFQ3|hydroxymethylbilane synthase|EC 2.5.1.61|Nodularia spumigena CCY9414|TrEMBL
MTSVISSPTRTIRIGSRKSQLALVQTYWVRDQLQKSFPDISFEVHTMSTQGDNILDVALA
KIGDKGLFTKELEVGMLNQEIDFAVHSLKDLPTNLPSGLTLAVITERENPADALVVHDKY
KDKQIETLPAGAVIGTSSLRRLAQLRNKFPHFTFKDVRGNLNTRLKKLDSGEYDALILAA
AGLERLGMSDRIHQILPKEISLHAVGQGALGIECRADDKEIINILKAIEHSETRDRCLAE
RAFLRILEGGCQVPIGVNTVIDGDNLTLTGIVASVDGQKLVKDTVTGAAKDAEKLGAELA
ALLREQGAQEILEEIFTEIQRGS
>D7AWZ0|hydroxymethylbilane synthase|EC 2.5.1.61|Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)|TrEMBL
MTGTPSHGTTADGAPDHGAPARLGTRRSTMATSQSRMVADAITARTGRVIELELITSFGD
VTKAHLTQLGGTGVFVNALRDELHAGTVDFAVHSLKDLPTTPAEGLVLAAIPERDDPRDA
LCARDGLKFADLPAGARIGTGSPRRVAQLAALRPDLVYVPIRGNAETRLGKVASGELDAV
VLAYAGLGRVGRTEDVTEVFEPEQMLPAPGQGALAVECSVERLDGDLAYLASVDHPATRA
EVVAERTVLSELEAGCAAPVGAYAQYDAETGRLRLRAAVVATDGAEAVRRERAADLASPG
DLAAATALGRDLARQMIAEGADRIVAEAFAERDTP
>D3QC97|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus lugdunensis (strain HKU09-01)|TrEMBL
MRKLVVGSRRSKLALTQSKQFIDKLKEINPDLEIEIKEIVTKGDQILDKQLSKVGGKGLF
VKEIQHELFNKEIDFAIHSLKDVPSILPEGLTLGCIPDRENPFDAYIAKNHTPLDQLPDG
SIIGTSSLRRGAQILAKYPNLEIKWIRGNIDTRLHKLETENYDAIILAAAGLKRMGWSDD
IVTTYLDKDVLLPAIGQGALGIECRSDDVELLALLKQVHNQQVADCVTAERTFLAAMDGS
CQVPIGGYAMNKPNGDIEFTGLIMTPDGKERYEHTESGNNPIELGNKVSDVLIEQGAYEI
IRKLNDQQLH
>F8VJA3|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella bongori (strain ATCC 43975 / DSM 13772 / NCTC 12419)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLIVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHPQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGEAPA
>Q2K3D6|hydroxymethylbilane synthase|EC 2.5.1.61|Rhizobium etli (strain CFN 42 / ATCC 51251)|TrEMBL
MQTKPFRIGTRGSPLALAQAHEARDRLMAAHNLSEEMFEIVVLTTKGDRITDRPLAEIGG
KGLFTEELEQKLVSGELDFAVHSAKDMPTHLPDGLHLSAYLPREDIRDAVVGRTAPKLID
LPHGATVGSSSLRRQALIRRMRPDINVITFRGSVETRLRKLDEGQVDATLLALAGLKRLG
KVEVITDVLDPDTFPPAPAQGAICIESRVGDTKIDDLLAAVNDATTFDSVSCERAFLAAL
DGSCRTPIGGYAVCEGDLIRFSGLIITPDGRSQHAVTTDGHRRDAAALGTRAGQDVRARA
GSAFFDDWH
>H5LDL8|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC13B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E1TBJ6|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia sp. (strain CCGE1003)|TrEMBL
MWQAEHVQCALHKLYPSCEVKILGMTTRGDQILDRTLSKVGGKGLFVKELEAALADGRAD
LAVHSLKDVPMELPPGFALSTIMEREDPRDALVSNHYDSLAALPAGAVVGTSSLRREAML
RMRYPHLEVRPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLGDRIRALLDPQDSLPAA
GQGALGIEIRADRADLAAWLTPLHHEHTAAAVEAERMVSRALGGSCEVPLAAYAEWHDGA
LHLRGVVATPDGRRVLSAQASAPAPTVERAVALGREVANALEQQGAMEIVRALSTASGPA
NSPVSGD
>I4VGI6|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus aerophilus KACC 16563|TrEMBL
MRTIKVGSRRSKLAITQTKWVIQKLSELNPSYSFEIKEIVTKGDQILDVTLSKVGGKGLF
VKEIEQAMLNHDIDMAVHSMKDMPASLPEGLVIGCIPEREDVRDALISKDHLRLHELPKG
AIVGTSSLRRSAQLLQERPDLEIKWIRGNIDTRLEKLKNEEYDAIILAAAGLSRMGWSQE
VVSEFLSPDTCLPAVGQGALSIECRGDDEELLQLLAQFTNEYTKKTVLAERAFLKQMDGS
CQVPIAGYATMNERDEIELTGLVASADGHTIIRETVTGTDPEAIGTACAKHMADKGAKDL
IDKVKKDLSSQ
>E6WPD3|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoxanthomonas suwonensis (strain 11-1)|TrEMBL
MDTLRIATRKSPLALWQSEHVAARLRAAHPGLEVVLVPLSTRGDEVLDRSLAAIGGKGLF
LKELEIAMERGEADCAVHSLKDVPMELEPGFVLPAVLERADPADAFVSNDFADLDALPQG
AVVGTSSLRRQAQLRARRPDLQLRDLRGNVNTRLAKLDAGEYHAIILACAGLQRLGLDAR
IRARLVPPQWLPAPAQAVVACECRAGDERTIGLLSLLEHAPTRAVIEAERALNRGLHGSC
HVPVAAYAELHDRTLRLQALVGSAADGRAVRAEGEGPAADPQTLGSRLAAELLERGAGEF
L
>C8UJI4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O111:H- (strain 11128 / EHEC)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E1VFU1|hydroxymethylbilane synthase|EC 2.5.1.61|gamma proteobacterium HdN1|TrEMBL
MSNHRIRIATRESALALWQAEHVRACLLAAHPGLDVEIIGMTTKGDKILDTPLAKIGGKG
LFVKELEVAMLEGIADIAVHSMKDVPVDFPEGLGLSVILEREDPRDAFVSNQYDTLDQLP
LGARVGTCSLRRQTQLRARRPDIEILELRGNVNSRLAKLDAGQFDAILLAAAGLKRLGFH
ERIRATLDPAASLPAVGQGAIGIECRTDDARTLALLAPLNHPDTHTCVSAERAMNHRLQG
GCQVPIAGYAELHGDQLYMRGLVGEPDGSRILRAEIRGARADAAALGAALADDLLAQGAK
EILARLYQSGH
>I4V128|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli HM605|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F0KD49|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium acetobutylicum (strain EA 2018)|TrEMBL
MKLTIATRKSKLAQVQTELIINVLKDKYGISSEKLLMETLGDKILDKSLADIGGKGLFIK
DIERILLEDKADAAVHSMKDVPFEVPDMFEIAAVTLRVDVRDVFVSRDGTHFKDLKNGAV
IGTSSNRRAAQLKMLRDDIKVVPIRGNVQTRIRKMGEEKLDGIILAAAGLKRLNMENIIT
DYFSVEEMIPAVGQGALGVEIKKENKNRDLFRKLDNKNSRMCVEAERSFMRTLNGDCHST
IGAYAEIVNGQMNVLGFYEIDGRRVKKDVSGNIEDYMSLGKTLAEKILEDK
>I5MML6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA41|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>G0BF09|hydroxymethylbilane synthase|EC 2.5.1.61|Serratia plymuthica (strain AS9)|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQQRLMASHPGLQVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPIDFPAGLGLVTICERDDPRDAFVSNRFASFDQLP
QGSVVGTSSLRRQSQLRERRPDLIVRDLRGNVGTRLAKLDNGDYDAIILAVAGLKRLGLE
QRIRSPLSPEECLPAVGQGAVGIECRLDDDATRALLAPLNHTATDIRVRAERAMNTRLEG
GCQVPIGSYAELEGDSLWLRALVGSPDGSQMVRGERRGPAALAEQMGVELAEELLARGAR
EILHDVYQGNPSA
>E7XIC6|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. NC_MB110209-0054|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>C7QWZ0|hydroxymethylbilane synthase|EC 2.5.1.61|Cyanothece sp. (strain PCC 8802)|TrEMBL
MAVSSPTRSIRIGSRKSQLALVQTYWVQKELQRHHPQHQFDVETMSTQGDKILDVALAKI
GDKGLFTKELEVAMEQNQVDLAVHSLKDLPTNLPTGLILGCVTERVDPADALVVNQKHLD
KQLDTLPEGAVIGTSSLRRLAQLRHHFPHLTFKDVRGNVNTRLKKLDEGEYDAIILAVAG
LQRLDMSDRIHQVIPSEISLHAVGQGALGIECREGDEEVLALLKVLEHEPTRDRCYAERA
FLRELEGGCQVPIGVNTEIEGDTLTLTGMVASLDGQTLLKDTISGPRESAEQLGRDLANR
LREAGAGEVLAAIFAQIERG
>F0NA47|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup B (strain NZ-05/33)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVILQADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>D7ASI0|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoanaerobacter mathranii (strain DSM 11426 / CIP 108742 / A3)|TrEMBL
MKKVIKVGTRSSELALVQTQMVINEIKKFRQDFEFEIVKITTQGDALIDKPVSEIGGKGV
FVKEIESALLKGEIDMAVHSMKDMPYEIPKGLKLMAVLKREDPKDVFVSRDGTQFMDLKE
GAKIGTSSLRRQVQLKALKPDIQIVPIRGNVRTRLKKMEELNLDGIVLSAAGLHRLGLES
IITEYFPPDVVVPAPCQGILAVEIAESFDNIFQEFYPYIVDRRTFFEASVERELLKVFGV
NCRQPFGAYAQYRKERDEEKINIKVVYQKEDKLLKSEVTGLIEETDKMIEKLIEEFGGI
>B7S2A8|hydroxymethylbilane synthase|EC 2.5.1.61|marine gamma proteobacterium HTCC2148|TrEMBL
MPTRTLTIATRESPLALWQAEYVRDALMSAHPRLEVNLLGMTSRGDQLLDVPLAKVGGKG
LFVKELETALLDGSADIAVHSMKDVPMSFPEGLTLGVICEREDPTDAFVSNNFESLAQLP
AGSVVGTSSLRRECQLRARRPDLQVKFLRGNVNTRLRKLDEGQYDAIILASAGLIRLGFG
ERIADSISVDDSLPAGGQGAVGIELREGDGDVLELLQTVHHPLTAQRVIAERAMNQRLNG
GCQVPIACFAEYLDNGHLRLRGLVGRPDGSEVLRAEAISSPEDAENLGISVANELLVQGA
AAILAEVYGD
>B5PM60|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Weltevreden str. HI_N05-537|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>G1ZR50|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 3030-1|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHKTALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q0EWI8|hydroxymethylbilane synthase|EC 2.5.1.61|Mariprofundus ferrooxydans PV-1|TrEMBL
MLQVFTSEGQKGTFRILNQEENSVPHIRIATRRSPLALWQAEYIAAELEKMSPDVTTELV
KIVTRGDKILDVPLAKVGGKGLFTKEIDEALFDGRADVAVHSMKDVPTQLPEGTSIRALP
ERADPRDAAATITGGGLDTLPEGATIGTSSLRRVAQLQARFPTFKFVSVRGNIQTRLSKM
GQEVDAIILAAAGIRRMGMEDQMHEFIDTEMLLPAVAQGTLGIQTRNDDDVVNALVDRLN
HADTVDRTRAERAFLARLEGGCQVPIAAFATLDGDQLTLKGLVGSVDGKIVIRREIVGLR
RDGAAMGIALADEILDAGARPILEALYAEGSHG
>F0KQ91|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia enterocolitica subsp. palearctica serotype O:9 / biotype 3 (strain 105.5R(r))|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPIAFPEGLGLVTICERDDPRDAFVSINYAHLDELP
AGSIVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDKGEYHAIILAVAGLKRLGLE
TRIRYAMPAEESLPAVGQGAVGIECRLDDNFTRQLLAPLNHRETELRVCAERAMNTRLEG
GCQVPIGSYAELDGDTLWLRALVGAPDGSEIIRGERRGPAENAEQMGVELADELLSRGAR
EILAEVYQDNPPL
>E8EDG3|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 2009085258|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H4B2R2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1150|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>B4VVK8|hydroxymethylbilane synthase|EC 2.5.1.61|Microcoleus chthonoplastes PCC 7420|TrEMBL
MSSTVTSPARTIRIGSRKSQLALVQTYWVQEQLHKHYPDRDFEVQTMSTHGDKILDVALS
KIGDKGLFTKELEVGMLNQEIDLAVHSLKDLPTALPEGLVLGCVTERENPADALVLHAKH
QGKQLDTLPEGAVIGTSSLRRLAQLRYHFPHFTFKDIRGNLNTRLGKLDAGEFDALILAA
AGLKRLDMSDRIHQVIPSEISLHAVGQGALGIECRGDDPEILDVLKAIEHSPTAQRCYAE
RAFLRELEGGCQVPIGVNTEIKGNNLILTGMVARLDGTSLIKDTVTGEATEAEALGVELA
QLLRQQGAQEILDEIFAQIQR
>B4VVK8|hydroxymethylbilane synthase|EC 2.5.1.61|Microcoleus chthonoplastes PCC 7420|TrEMBL
MSSTVTSPARTIRIGSRKSQLALVQTYWVQEQLHKHYPDRDFEVQTMSTHGDKILDVALS
KIGDKGLFTKELEVGMLNQEIDLAVHSLKDLPTALPEGLVLGCVTERENPADALVLHAKH
QGKQLDTLPEGAVIGTSSLRRLAQLRYHFPHFTFKDIRGNLNTRLGKLDAGEFDALILAA
AGLKRLDMSDRIHQVIPSEISLHAVGQGALGIECRGDDPEILDVLKAIEHSPTAQRCYAE
RAFLRELEGGCQVPIGVNTEIKGNNLILTGMVARLDGTSLIKDTVTGEATEAEALGVELA
QLLRQQGAQEILDEIFAQIQR
>B4VVK8|hydroxymethylbilane synthase|EC 2.5.1.61|Microcoleus chthonoplastes PCC 7420|TrEMBL
MSSTVTSPARTIRIGSRKSQLALVQTYWVQEQLHKHYPDRDFEVQTMSTHGDKILDVALS
KIGDKGLFTKELEVGMLNQEIDLAVHSLKDLPTALPEGLVLGCVTERENPADALVLHAKH
QGKQLDTLPEGAVIGTSSLRRLAQLRYHFPHFTFKDIRGNLNTRLGKLDAGEFDALILAA
AGLKRLDMSDRIHQVIPSEISLHAVGQGALGIECRGDDPEILDVLKAIEHSPTAQRCYAE
RAFLRELEGGCQVPIGVNTEIKGNNLILTGMVARLDGTSLIKDTVTGEATEAEALGVELA
QLLRQQGAQEILDEIFAQIQR
>B4VVK8|hydroxymethylbilane synthase|EC 2.5.1.61|Microcoleus chthonoplastes PCC 7420|TrEMBL
MSSTVTSPARTIRIGSRKSQLALVQTYWVQEQLHKHYPDRDFEVQTMSTHGDKILDVALS
KIGDKGLFTKELEVGMLNQEIDLAVHSLKDLPTALPEGLVLGCVTERENPADALVLHAKH
QGKQLDTLPEGAVIGTSSLRRLAQLRYHFPHFTFKDIRGNLNTRLGKLDAGEFDALILAA
AGLKRLDMSDRIHQVIPSEISLHAVGQGALGIECRGDDPEILDVLKAIEHSPTAQRCYAE
RAFLRELEGGCQVPIGVNTEIKGNNLILTGMVARLDGTSLIKDTVTGEATEAEALGVELA
QLLRQQGAQEILDEIFAQIQR
>D3S5V4|hydroxymethylbilane synthase|EC 2.5.1.61|Methanocaldococcus sp. (strain FS406-22)|TrEMBL
MITIGTRGSKLALYQANKVAELLKNLGYDVKIKIIKTTGDRVLDKKLSDIGIGVFTKELD
LAMLNNEIDIAVHSLKDIPTIWNENLMVGAVLERDSYYDLLIWNKDVDFDENSKIVIGTS
SLRRRAFLKFLYPNAKFELLRGNVDTRLRKLKENLYDAIVLSEAGIIRLGINLDDFNYKR
LNILPAPAQGIIAVACKRDDEEMKDILKEINHEKTYLESLCERAALNEFGGGCSVPFGAL
AVYDEKNEILKLDAGVVINDELKSASGEIKCKIDEIDKAIELGKKIGMKLKN
>H4I3K1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC1A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E8K4C8|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus parasanguinis ATCC 903|TrEMBL
MRSIKVGTRKSQLAMTQTKMVVERLKECHPEVDFELVPYKTQGDRLVHVSLQTIGGKGVF
VKEIEQALLNKDIDIAIHSLKDVPSILVDGCTIGAIPEREDVRDCLIFREEGMTLATLPQ
GAVVGTSSIRRQVQLQSLRNDLQFKPLRGNIDSRIRKLQEGECDAIVLAAAGLKRIGYLD
QSPSLNLEFLDPQTFIPAVSQGALAVECREDDEEVLEILASIHDKEVENCIQLERSFLSL
MNADCTFPVGAHAQYIDGHYHLETMLADAKDRCLYVALTSKDGSDLPKLALEQLMEKGAL
TDKWWEA
>I4I6V9|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 9809|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSQNQD
YQLDTLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LERLGLGDRVHQVIPAAISLHAVGQGALGIECRDADPEVLEVLKVLEHAPSRDRCYAERA
FLRELEGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VREAGAGEILAQIFAEVGR
>B5SI23|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia solanacearum IPO1609|TrEMBL
MWQAEYVRAALQKYYPACDVSILGMTTRGDQILDRSLAKVGGKGLFVKELEVALAEGRAD
LAVHSLKDVPMELPPGFALPAILEREDPRDAFVSNQYADLAALPAGAVVGTSSLRREASL
RARFPHLVIQPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLSERIRAVIASDVSLPAA
GQGALGIETRADRTDVQAWLAPLHHLPTALAVTAERAVSRRLGGSCQVPLAAFAHWTDAG
ALRLRAFVASQDGRRKLAAEGEATPATLAEAEALGARVAQQMLDGGAWDILATLGADAPP
AT
>E8X345|hydroxymethylbilane synthase|EC 2.5.1.61|Acidobacterium sp. (strain MP5ACTX9)|TrEMBL
MTQIRIGSRGSQLALWQANHIAAELRAHGHQVEIEVIRTTGDRMQQPGFVPPPGLDGKGI
FIKEIEDALLDGRIDLAVHSYKDLPTTIDPRFTIAAVPPRADARDAFVCEPYWALHTLPH
AGRIGTTSPRRRAQLLALRPDLTFVELRGNIDTRLRKLEEGACDALVLACAGLDRIARTE
SVHQRFDVDELTPAPGQGALALETRSPAHALDTEDPTRDPAIYKAIRALEHPETRFATDA
ERAFLAEMGGGCELPLGAHCLSTSGVYRLYAQVLSPDGEYMVQTTLDRHPEEPAAALGQR
AAEILKAQGALDLLSTAV
>F9KE93|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21235|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDRNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>C9R2R1|hydroxymethylbilane synthase|EC 2.5.1.61|Aggregatibacter actinomycetemcomitans serotype C (strain D11S-1)|TrEMBL
MTQKSLKIATRQSPLALWQANYVKDLLQQLYPDLNVELVPMVTKGDVILDSPLAKIGGKG
LFVKELENALLNKEADIAVHSMKDVPMQFPEGLGLAVICKREDPRDAFVSNSYRTLAELP
QGAVVGTSSLRRQCQLKTLRPDLEIRSLRGNVGTRLSKLDNGDYDAIILASAGLIRLGLA
ERIASFIDVEQSLPAAGQGAVGIECRTDDVAVQQLLAPLADAETTSCVLAERAMNHHLQG
GCQVPIGGYAVLRDSELYLRALVGSVDGSTIIRAEGKSAVENADVLGVQIAEQLLAQGAD
KILQDIYA
>I0XDG3|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CO-23|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E4QNA5|hydroxymethylbilane synthase|EC 2.5.1.61|Methylovorus sp. (strain MP688)|TrEMBL
MTSTSPISIPEKLVIASRESALAMWQARHIQARLQALYPSTQVEILGMTTTGDQILDSPL
ARIGGKGLFVKELEQALADGRADLAVHSMKDVPMHLPEGFAMAAIGEREDPRDAFVSNDY
PSLEALPAGSIVGTSSLRRQSQLQARFPHLVIESLRGNLQTRLRKLDEGQYAAIILAAAG
LIRLGLGNRIAQTIAPEDSIPAVGQGALGIEINAARTDLLTVLAPLNHADTAACVEAERG
MSRALAGSCTVPLGAYATKLGENITIHGFVASVDGKQMLRAEATGNAAKPELLGQQLAQS
LIARGADKILQALAEQSAHG
>G0EGU1|hydroxymethylbilane synthase|EC 2.5.1.61|Pyrolobus fumarii (strain DSM 11204 / 1A)|TrEMBL
MKLRVAARGSKLSLIQVKLAMDWFRRSIPDLDYEVVIVKTRGDIHQDKPFHMIGGKGVFE
KEVNLAVLDGRADVAVHSLKDVPSMVDPRLVLAGVPPRDPPYDVLVVRDGYEPNLEALPK
GAVVGTASARRRAAILHVRPDLRVEVLRGNVDTRLRKLVSGMYDAIILAEAGLKRLWDEL
PEELRSSISYARLDPRLVPPAPAQGIIGVYTLAERKDLVEALRKASDEKALVEARAERAF
LSVFGGGCHVPVGVLARLEGDTLGLIAVLYSQDGSKRVEVSAEGDASNPELVGIQAALEL
RKRAVEEGMIA
>D2B2U6|hydroxymethylbilane synthase|EC 2.5.1.61|Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)|TrEMBL
MSSVSSPLRLGTRRSLMATTQSGLVAARLTELTGRAVELVGVTTFGDVTKANLTQLGGTG
VFVSALRDKLIDGEIDFAVHSLKDLPTTQDPRVVIAAIPPRDDPRDALVSTAKLADLPAG
SKVGTGSPRRIAQLRVLRPDLEYVPIRGNADTRIGKVTSGELQGVVLAAAGLGRLGREAE
ISQVFEVEEMLPAPGQGALAVECRADRTDLIEFLSVLDDARTRAAVTAERAVLNALEAGC
AAPVGAYSADDGQNLILTAAVVAVDGKRAVRKSTAGTLSAPMDLGRDLAAEMIAEGAGTL
IGEQAH
>E8KG62|hydroxymethylbilane synthase|EC 2.5.1.61|Actinobacillus ureae ATCC 25976|TrEMBL
MKDILRIATRQSPLALWQANFVKKELEKRFPELQVELVTMVTKGDIILDTPLAKIGGKGL
FVKELELALLEKRADIAVHSMKDVPMTFPEGLGLAVICEREDPRDAFVSNKYQNLDELPA
GAVVGTSSLRRQCQLMAKYPHLEVKSLRGNVGTRLSKLDNGEYEAIILASAGLIRLGMPE
RIRSFIAVEQSLPAAGQGAVGIETRVNDERVLNYLASLNHNPTACCVMAERAMNTRLQGG
CQVPIGGFATLNGNEITLNALVGALDGSTIIRASGVADIEDAEQLGISVAEQLLAQGADK
ILAEVYKDE
>D0JBN5|hydroxymethylbilane synthase|EC 2.5.1.61|Blattabacterium sp. subsp. Blattella germanica (strain Bge)|TrEMBL
MKKIIRIGTRNSPLAVFQAQKVQKLLKKEGYFSHLFKIKSEGDLIQNVPIHALKHVGVFT
KKLTNIMLSGEIDMAVHSLKDVPINLPEGIILSAFLKRESFFDSLVYKGSSDFLYDPKIH
AVIATGSIRRSAFWKNRYPHHGLIDLRGNINTRLKKLQNSSWKGALFAQVGLERLGILNN
FKCLNCKILDWMIPSPGQGIIVVSTLEKKDSINSLIKKLDDIETRLSANIERQFLKTLGG
GCISPIGAHAKIKNKIIYFTGMLLSLDGMHKIKKTRIGTNYDLIGFQCAEEILKEGGREI
LEGIKNNIS
>H7XBH3|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 23216|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQILLLRPDLEIISLRGNVNSRIEKLKNNEFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILKLLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLRDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>I2NUD1|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria sicca VK64|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKTLYPDCEVEILGMTTRGDQILDKTLSKIGGKG
LFIKELEQALQDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMS
KGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
ERIRLILSEADSLPAAGQGALGIEIAAHRTDLLDVLKPLNHDVTHACVTAERALARALGG
SCQVPLAAYCTEEDGLLTLRGLVGHPDGSVILQADAQAPSAYADALGRAVAKKLADDGAQ
ELIEAVLKEQAE
>I5V9Q5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4013|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>O69101|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus stearothermophilus|TrEMBL
MRKIIVGSRRSKLALTQTNWVIEQLKRLGAPFEFEVKEIVTKGDKIINVTLSKVGGK
>B8CHV8|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella piezotolerans (strain WP3 / JCM 13877)|TrEMBL
MWQAEFVKAELEKIHEGLTVELLPMSTKGDIILDTPLAKVGGKGLFVKELEVAMLEDRAD
IAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNNFSSINELPQGAVVGTSSLRRQCQI
RAARPDLQIKDLRGNVGTRLAKLDAGNYDAIILAAAGLKRLKLEERITSFISAEDSLPAN
GQGAVGIECRTDDARVKALLAPLEHLETRQRVIAERAMNTRLEGGCQVPIGAYAEIDGDT
LSLRGLVGNPDGSQVIEAATSGNKNDAEQLGVALAEELLSKGAKTILDAVYAKA
>D3MHN8|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes SK187|TrEMBL
MPLWCRRPAELSVNLSDCRLESASVLSATIGNMSAIRLGTRASTLATTQSEMVAGLLRSE
GLDVNLTTITTHGDTSTASLAAMGGIGVFASAIRAALLEGEADIAVHSFKDLPTGRPLGL
AIGAVPARADPRDALVARDGLTLHDLPQEASVGTGSPRRAAQLLAVRPDLTIVDIRGNVD
TRLGRVKGLGRYAKNGGKEDLDAVVLAASGLARLGHSGAVTEFLDPSVVLPAPAQGALAV
ECRTADSRHGKLAKALARIDDRRTRLAATAERAVLSHLEAGCAAPIGALAQLKPVSGKSL
QVLTLDVVVAAVDGSRTVREQVSVELPAEVEPALAAAHTLGVTAAEELLDDGAADVADLK
ASGSTR
>D3MHN8|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes SK187|TrEMBL
MPLWCRRPAELSVNLSDCRLESASVLSATIGNMSAIRLGTRASTLATTQSEMVAGLLRSE
GLDVNLTTITTHGDTSTASLAAMGGIGVFASAIRAALLEGEADIAVHSFKDLPTGRPLGL
AIGAVPARADPRDALVARDGLTLHDLPQEASVGTGSPRRAAQLLAVRPDLTIVDIRGNVD
TRLGRVKGLGRYAKNGGKEDLDAVVLAASGLARLGHSGAVTEFLDPSVVLPAPAQGALAV
ECRTADSRHGKLAKALARIDDRRTRLAATAERAVLSHLEAGCAAPIGALAQLKPVSGKSL
QVLTLDVVVAAVDGSRTVREQVSVELPAEVEPALAAAHTLGVTAAEELLDDGAADVADLK
ASGSTR
>Q16AR4|hydroxymethylbilane synthase|EC 2.5.1.61|Roseobacter denitrificans (strain ATCC 33942 / OCh 114)|TrEMBL
MTVMLPSPDSPLKIGTRGSPLAMAQAFETRARLMQAFDLPENAFTIVVIKVTGDMIQDRA
LKDIGGKGLFTREIEEDLLSEKIDIAVHSMKDMPTLQPDGLILDTYLPREDVRDAFISPT
LKGIADLAQGAVVGTSSLRRKAQLLNRRPDLNVVEFRGNVQTRLKKLADGVAECTFLACA
GLSRLKMDEVPATPIETDHMLPAVAQGAIGIERRIADTNTAELLSAIHDGPTGQRLAAER
NFLLTLDGSCETPIAGLAELSGDHLRLRGEVLRPDGSEALNGERSGPISDGAAMGRDLAE
KLLKRAGPSFFDWH
>I4XZA8|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas chlororaphis O6|TrEMBL
MSSREIRIATRKSALALWQAEHVKARLEAAHPGLIVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTYSSLDELP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRISSSISVDDSLPAGGQGAVGIECRTADSEIHKLLAPLHHADTADRVTAERALNKHLNG
GCQVPIACYAVLEGDQLWLRGLVGEPSGGVLLSAEARAPRSAAAALGVQVAEDLLAQGAD
DILRAVYGEAGEE
>E7Y7F4|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. CASC_09SCPH15965|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>A1F6M1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae 2740-80|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>C5CSC7|hydroxymethylbilane synthase|EC 2.5.1.61|Variovorax paradoxus (strain S110)|TrEMBL
MYFLGAALSNIVIATRESRLALWQAEHVQALLQERGHAVSLLGMTTRGDQILDKSLSKVG
GKGLFVKELELALEEGRADIAVHSLKDVPMDLPEGFVLACVLEREDPRDALVSPRHASLD
ELPQGAVVGTSSLRRVVLLRALRPDLRIEPLRGNLDTRLRKLDQGHYDAIVLAAAGLKRL
GLEHRIRVAFDPDTMLPAAGQGALGIEVRADRTDLIALLAALSHSRDWLATAAERAVSRS
MGGSCSMPLAAHARWQADGALRVDAAWGDPEGNAALVRVHAQAPAADFAQAGALGERAAA
LLRDAGAH
>A6SX35|hydroxymethylbilane synthase|EC 2.5.1.61|Janthinobacterium sp. (strain Marseille)|TrEMBL
MKFPPPKKLVIASRESRLAMWQAEHVREKLAILYPQCSIEILGMTTRGDQILDRTLSKVG
GKGLFVKELEVAIAEQRADLAVHSLKDVAMTLPDGFELAAVLEREDPRDAFVSNEFDTLE
ALPAGAIVGTSSLRRQALIAARYPQLVIRPLRGNLDRRLGKLDNGEYAAIILAAAGLKRL
GLTARIRSYLPPEQSLPAPGQGAMAIEILSERADLKEWLAPLNHTETALAVTAERTVSRN
FGGSCQIPLAAFATIDGVNMRLRAIIATPDGSKMASADLSGAANAPEALGRQIADALQQQ
DAAAILALCKTDADGDV
>B5ZTC6|hydroxymethylbilane synthase|EC 2.5.1.61|Rhizobium leguminosarum bv. trifolii (strain WSM2304)|TrEMBL
MQTKPFRIGTRGSPLALAQAHEARDRLMAAHHLPEEMFEIVVLSTKGDRITDRSLAEIGG
KGLFTEELEQQLTTGELDFAVHSAKDMPTKLPDGLHLSAYLPREDIRDAVIGRTAPKLID
LPHGATVGSSSLRRQALIRRMRPDINVVTFRGLVETRLRKLEEGQVDATLLALAGLKRLG
KVEVLTDILDPDTFPPAPAQGAICLESRIGDTQIDDLLAPVNDAATFDTVSCERAFLAAL
DGSCRTPIGGYAVCEGDLIRFSGLIITPDGRSQHAVTTDGHRRDAAALGTRAGQDVRARA
GSAFFDDWH
>H4E6Z2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG2018|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>C6D878|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus sp. (strain JDR-2)|TrEMBL
MGAHNNGPRTIVVGTRQSALALTQTGQVIDELKRISEKHGFDYHFEIRKIVTKGDRILDV
TLSKVGGKGLFVKEIEQALLDGEIDMAVHSMKDMPYELPEGLMNGATPRRVDPRDCLIMK
QGSSLDDLPAGARVGTSSLRRSSQLKNIRPDLKLDSIRGNIDSRIRKLETEGFDAVVLAA
AGLSRMGWQDRISAFIPVDLSIPAVGQGALGIECRTADAGVRELLNLLNDTETSLSVRAE
RSFLGALNGGCQVPIGAFAVVHKKSEDSFDNAELELTGMVGSPDGEVMLKEIRKGTDPEQ
LGRDVAAALSARGADRILAEFGG
>Q2NQD4|hydroxymethylbilane synthase|EC 2.5.1.61|Sodalis glossinidius (strain morsitans)|TrEMBL
MIKSVMTMQDNLLRITTRQSPLALWQAGYVRDELLRHHPHLQVELVPLVTRGDITLDTPL
AKVGGKGLFIKELELALLEHRADIAVHSMKDVTVSFPAGLGLCVLCERDDPRDAFVSPRY
ANLDVLPPGAIVGTSSLRRQCQLRERRPDVIVHDLRGNVGTRLAKLDRGNFDAVILAVAG
LKRLGLEDRIRHAIDPADSLPAVGQGAVGIECRLDDARTLALLAPLHHRETSLRVGAERA
MNARLQGGCQVPIGSYAVLDGEEIWLRALVGSPDGTTVIRSEGRAPLAQAEQLGLRLADD
LLNRGARAILADVYQDNPPQ
>F8ZRG2|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-70A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>B1QPC8|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum Bf|TrEMBL
MNENLSEFSVFFYIFCGIYFKSELYKIIDHLDYEPNGSNNKKYEYTFVLKDKTKLNFEVK
TLDCDPFSKDAKILKDINLKDGDILGKAYFPNSNLEDFIDYKTNGIVEISSSYRQTNRNI
RNIKKKFETRNDKDINIGVIVINYGTSREEFFSYLLNDEYGLINVQDFGNIDNLVLFSMC
GHTTLMMNEIYENEHIFSVSINTDRYKKDIFNSLRLDNYIIKDGKIESRFYDFKTEKFSL
YKYIMRNGFVTIQPYYIEDNIINDELSELRDIYNDLNEISKRIK
>B7RJR5|hydroxymethylbilane synthase|EC 2.5.1.61|Roseobacter sp. GAI101|TrEMBL
MAQAVETRARLSAAFDLPLTAFEIVVIKVTGDMIQDRPLKEIGGKGLFTREIEEDLLAGK
IDIAVHSMKDMPTVQPGGLLLDTYLPREDPRDAFVAPLMSALDQLTEGAVVGTSSLRRRA
QLLHKRPDLQVVEFRGNVQTRLRKLADGVAECTFLAMAGLNRLGMENVPATPIDDTDMLP
AVAQGAIGIERRAGDLDTEALLAAIHDTPTGQRLIAERAFLLTLDGSCETPIAGLATLDG
DTLHLRGEVLRPDGSEVISGDRSGPIGDGGQMGVDLARELLSQAGPNFFDWHATKQG
>H0DB21|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus VCU006|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>A5WJM5|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis (strain F11)|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>F4A5D4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum BKT015925|TrEMBL
MKIIVGSRGSKLALTQTNWVIDKIKENHPQVNFEIKIISTKGDRIQHMPLDKIGGKGLFV
QEIEEQLINGQIDLAVHSMKDMSTDIPEELKFSYVPVREDYRDVLILNKKYKSIDELPKG
AKIGTGSKRRKYQLLDYRNDLKIVPIRGNVDTRIKKIETENLDGIVLASAGIKRLGLEDK
IDYNIFYLEKDIMLPSPAQGILALEIKRGRKDLENILKSIEDEISTIQAEAERAFLKGVN
GGCHVPIGALCSINKDTVEVTGLLGKEDASKIVRKTLVGSIDEAEYIGYELAKIVLKEIN
>C6VRW7|hydroxymethylbilane synthase|EC 2.5.1.61|Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114)|TrEMBL
MHIKIGTRGSKLALWQAYYVEELLQRGGVETEIVIIETKGDKILDRSLSKIGSKGVFTEE
LEDQLRSGDIDIAVHSAKDLQSHLDDAFEIIAFTEREQANDVLVSHDTTLSLKSGESFTV
GTSSTRRVAVLKHYYPHIKTVDMRGNLQTRLRKLEEGQCDALLLAFAGVHRMEYDDKIAE
HLLLDEFTPAVGQGSVAIETAVALDPAKKSKLRELLNNEHTETCLLAERAFLKRLQGGCS
IPVFGMATLHEDEIRMTGGIISLDGTELIRKTETGATAFPQELGTALAEELLAAGADRIL
QTIRNHI
>G1C9M1|hydroxymethylbilane synthase|EC 2.5.1.61|Candidatus Kinetoplastibacterium oncopeltii|TrEMBL
MNKKITIATRASKLASAQAEYVRDLIKSLYPEVMIDFLVIVTQGDKILDRALAKVGGKGL
FVKEIELALLNGDADLAVHSMKDVPAEMTDSLDICSILKRHDPRDVFASNKYSSLEELPL
GSIVGTSSLRREAQLKSVYPKISVKCLRGNVDSRLKKLDDGDYSGIILAAAGLERINLGH
RISSYIDTSISLPAAGQGAIGIQIRNDRIDIRDLVASLSCNDTTICVKTERIVMKVLGGS
CQVPLAANAYIEDRNIFLRAMVSSIDGKKVIHSNGSVDVDNWQILGESVANDLLSKGAYE
ILHNV
>Q3EWK7|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus thuringiensis serovar israelensis ATCC 35646|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDDE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDAITERTVAAERVFLHRLEGG
CQVPIAGYATLKENDTIELTALVGSMDGSVLLKETVVGTNPEEVGLEAAGRLIKQGAKEL
ILAANKEQQ
>F0HEF9|hydroxymethylbilane synthase|EC 2.5.1.61|Turicibacter sp. HGF1|TrEMBL
MRVVVGTRGSKLALTQTQWVIDQLRKYHPEVEFEVKIIKTKGDLIQHVSLDKIGDKGLFV
REIEQQLLDKEIDIAVHSMKDMPSKLPKGLKFAAVPKREDPRDVLILKDGYKTLEDLPKG
AKIGTGSKRRKYQLLKYRPDLDILSIRGNIDTRIRKIEDENLDGIVLAAAGILRAGMSEM
ISSYIPVDIMVPAPAQGALAIQIREADLEIEALIESIKDVETEIRVAAERAFLAGVNGGC
HIPMGAYCELEGEKLKLTGLYGSENGNCLVRKCLEGGIESPIELGLEVAQFVLKEYDNYE
R
>H7USL2|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 317/04|TrEMBL
MKELVIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEQILEFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSEFKGFGESLAKEFIAKGAKEI
LKKAESMI
>G2LHZ1|hydroxymethylbilane synthase|EC 2.5.1.61|Chloracidobacterium thermophilum (strain B)|TrEMBL
MTLSVPTARPDADLVIGSRGSALALWQAEWVKAQLERAVPTRRVAIQIIKTTGDAILDAP
LSKIGGKGVFTKEIEEALLAGVVDLAVHSLKDLPTRLPDGLKLGCVTQREDVRDALVARD
GIRSLDELPPRAIIGTSSLRRQAQLLARRPDLQLADLRGNVGTRLQRVDEGRYDAIILAA
AGLSRLGFEARIAQRIPTDIMLPAVGQGALGIEIREGDSTTQAAIEVLAHHRTWHACEAE
RAFLHGLGGGCQVPIAAHAVVDDEGRLRLRGLVARVDGTRLVQDELTGDARFAEDIGREL
AERVLAQGAAELLAELHT
>Q1R4D3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain UTI89 / UPEC)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F8ALM4|hydroxymethylbilane synthase|EC 2.5.1.61|Methanothermococcus okinawensis (strain DSM 14208 / JCM 11175 / IH1)|TrEMBL
MKIIIGTRGSKLALAQTYYIKNLLENLNENLSIDVKIIKTTGDKNQKSKLSELGLGVFTK
ELDTKMLNNEIDIAVHSLKDVPTVWNENLTISATPKRESYHDLIIWNKNNDIDIEKDNLI
VGTSSIRRKAFLSIKYPNLKTKLLRGNIDTRLRKLRENNYDAIILAEAGLNRLKIDLSEF
NYKRLKILPAPAQGVIGVASRKDDKEIIDILKKINDNKTYLESIAERYALREYGGGCQAP
FGALSKYDTKNNELYLTCDVVYTLNGKNNIISKEDKIQCDIEDIHLAKKIGIKLGKEIKE
AESEKSEKHIL
>E2WVS5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 1827-70|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>G6XTI7|hydroxymethylbilane synthase|EC 2.5.1.61|Agrobacterium tumefaciens CCNWGS0286|TrEMBL
MQTKPFRIGTRGSPLALAQAYETRNRLMAAHGLPEDMFEIVVLSTKGDRITDRALSEIGG
KGLFTEELESQLLSGELDMAVHSSKDMPTVLPEGLYLSAFLPREDVRDAFIGRTAPKLLE
LPQGAVVGSASLRRQALIRRLRPDLSVIIFRGQVDTRLRKLEEGQADATLLAFAGLKRLG
KDNVPTEILDPKEFPPAPAQGAIGVESRIGDTRMDELLAPINDRPTYDAVTCERAFLAAL
DGSCRTPIAGYATCEGEELYFSGLILTPDGQTSHNIEISGNRKDAAKLGRQAGEEVRAKA
GSNFFEGWN
>C6R7U3|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium tuberculostearicum SK141|TrEMBL
MFQIGTRGSKLATTQAGHVRDWLIDAGFDSQLHIVTTAGDVNMAPVERIGVGVFTQALRE
ALYAGECDIAVHSFKDLPTAPDERFRLVVPQRQDSREALVARDGLSLAQLPQGARVGTSA
PRRISQLAALRPDLEIRPLRGNIDTRMSKVTDGELDAVLLAYAGLLRGGYADRATEIFEP
SVFMPAPAQGALAIEAVAGTEAAAALDAIVDDRASAAAAGERAVLARLEAGCTAPVAATS
RWDGDQLTVRGGVFALDGSRQLTATASGSAAEAADLGARISDELFAGGAAELLGK
>C6R7U3|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium tuberculostearicum SK141|TrEMBL
MFQIGTRGSKLATTQAGHVRDWLIDAGFDSQLHIVTTAGDVNMAPVERIGVGVFTQALRE
ALYAGECDIAVHSFKDLPTAPDERFRLVVPQRQDSREALVARDGLSLAQLPQGARVGTSA
PRRISQLAALRPDLEIRPLRGNIDTRMSKVTDGELDAVLLAYAGLLRGGYADRATEIFEP
SVFMPAPAQGALAIEAVAGTEAAAALDAIVDDRASAAAAGERAVLARLEAGCTAPVAATS
RWDGDQLTVRGGVFALDGSRQLTATASGSAAEAADLGARISDELFAGGAAELLGK
>B9BQX0|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia multivorans CGD2|TrEMBL
MNSEILAAGPRPAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQ
ILDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMMLPDGFALAAIMQREDPRDA
FVSNDYASLDALPAGAVVGTSSLRREAMLRARYPHLQVLPLRGNLDTRLSKLDRGDYAAI
ILAAAGLKRLGLEARIRALLDVEDSPPAAGQGALGIEIAAHRADVAAWLEPLHDAQTALA
VEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTIDGTRVLTAEECASVVTVADAL
ALGRAVSDELEAQGALEIVRALLAGSQAGKGEA
>D9S5Q5|hydroxymethylbilane synthase|EC 2.5.1.61|Fibrobacter succinogenes (strain ATCC 19169 / S85)|TrEMBL
MSDLKLRIATRKSALALAQTTMVADAIVAANSVIGNAADSNNARDSLTYELVSMTTEGDR
RLDKSLASFGGKGVFIKELEIALLEGRADIAIHSLKDMPAEVLPQFKLAAVLKREDPRDA
FLSRGGSAGIRFMDLPAGARVGTGSIRRVVQLKALRPDLEYVPIRGNIQTRIGKLAELDG
VVLAAAGLKRMGLADQVTEYFSTEQMLPASGQGILAIETLNDATVQESRVTGRADLAQIL
ARVNDVATYCIASAEMAYLKALNAGCQFPVASFAEFVCEDGIENRGTCGALEENANRIAQ
TLKIRGIYWDEKSEKLLRAEVAGNVDLNSEDCVQQSKNLGIELACAIQKQL
>H1T1C6|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21264|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>H5FLN4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC10E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H7T8Q4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 1417|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>G1C9L9|hydroxymethylbilane synthase|EC 2.5.1.61|Candidatus Kinetoplastibacterium crithidii|TrEMBL
MSLSKKIVIATRASKLALWQAEYVRNNLLLFYPEYSVDLLTIITKGDRFLDTSLSKIGGK
GLFVKEIEKSLLDNVADLAVHSMKDVPADIQNDLEICSIMHREDPRDAFISNTCFSMDEL
MPGSVIGTSSLRRESQIKNLFPELIVKSLRGNLDTRLNKLDSGDYDAIILASAGLKRIGY
NARIKQYIDSDVILPAVAQGALGLQIRSDRDDMRALLSVLSCVDTTACVSAERSFLRMLG
GSCQFPIAAYATLIGNNLLLKGLVASVDGNNIIKSEIFGPVSTAADLGEALAHDILSKGG
DKILNSLSF
>E4NS69|hydroxymethylbilane synthase|EC 2.5.1.61|Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 / PR3)|TrEMBL
MKRGTLRLATRGSDLALRQTASVRDTLADRRFDVELVEVETRGDQIRDELLHRLGKTGAF
VRALDERVLDEEVDAAVHSMKDMPTEHPRDLVVAGVPERAPANDVLLTPDGTAFENLPAG
SVVGTSSLRRKAQILSARPDLEVEPLRGNVDTRVEKLLAPTLQREHEARVDDDSDKKANS
AEASASGEEYETDFDRTIEEWFDDLSEIERRSLERDVETEYDAIVLAEAGLKRSGLLHRV
EYDRLPPTEFVPAPGQGAIAVTARRDHENLDRIQDALDDPRTRVTTTVERTVLAELGGGC
IAPIGVHAKLQGEHVHVTARVLSTDGEEEVSASRNLPVHNHANAAAEFAESLASQGAADL
ISEARDDARDEEDEK
>B1HEQ0|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei S13|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAVVDALVAASAQAQKGGA
>E6KZP7|hydroxymethylbilane synthase|EC 2.5.1.61|Aggregatibacter segnis ATCC 33393|TrEMBL
MGTLSPVLQESKKIKWKLTIRANNGRIKHIRSLSYLVIMFKKTLKIATRQSPLALWQANF
VKARLQQLYPDLSIELVTMVTKGDVILDSPLAKIGGKGLFVKELENALLNNEADIAVHSM
KDVPMQFPEGLGLSVICKREDPRDAFVSNTYRTLAELPPGAIVGTSSLRRQCQLKALRPD
LEIRSLRGNVGTRLSKLDNGDFDAIILASAGLIRLGLADRITSFIEVEQSLPAAGQGAVG
IECRTNDEQVKQLLAPLADVETTYCVLAERAMNNRLQGGCQVPIGGYAVLRESMLNLRAL
VGSVDGSTIIRAEGQSAVENAEILGVQIAEQLLAQGADKILQNIYA
>A8LZJ0|hydroxymethylbilane synthase|EC 2.5.1.61|Salinispora arenicola (strain CNS-205)|TrEMBL
MSVPLRLGTRGSALAMAQSGQVAQALTAATGNPVELVEVVTAGDRSAAPVHRLGVGVFVS
ALRDALTARTIDFAVHSFKDLPTAAAPGLHVAAVPPRQDPRDALVARAGRTLAELPPGAR
VGTGALRRIAQLHALGLQLDVQPIRGNVGTRLARVLGPEADLDAVVLARAGLARLDRTDT
ITETLDPMLMLPAPAQGALAVECRSDDSDLVELLAVLDHAPSRATVVAERALLATLEAGC
SAPVAAYAELAEGDVGEEIYLRGAVISPDGTRDLRLSRTGTPADAVEIGKALAADLLELG
ADSILGQEGHFGPGTQQFGSTV
>E1P8X5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli OR:K5:H- (strain ABU 83972)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F9PKL4|hydroxymethylbilane synthase|EC 2.5.1.61|Actinomyces sp. oral taxon 175 str. F0384|TrEMBL
MTTTGTGSWRRLRLGTRGSRLALTQSGQVAEALMAAGGGGAAAAAGKASEGSGGLGIDLV
TVRTDGDGDRTPLRQLGGVGVFAARLRHALLDGEVDLVVHSFKDLPTQPVEGLEVICVPP
REDPRDALCARDGLTLADLPEGARVGTGSPRRAAQLLAARPDLEVVDLRGNVPTRLARVR
GLEVVGVGTDEPVAPSRADAAGDLDAVVLALSGLRRLGLEHCASEVLDLETMLPAPAQGA
LAVEARADEDSAELARAVAALDDEPTRLAVTAERALMARLGAGCAAPVGAWAHLRGGGQE
PREEHAEHGTGWNEEFGGNDTAATRTRQGAGTGQDAGAASGGPRPVVAADRGDERGGTEP
AGAAGPQGSEVSRRSPRVLVLRAVVTSLDGGQEVGCELSTELPEATGGPRTPGDTAAVRA
AEALGVRAAEVLLEDGADQIVDLHANKPRRD
>F9PKL4|hydroxymethylbilane synthase|EC 2.5.1.61|Actinomyces sp. oral taxon 175 str. F0384|TrEMBL
MTTTGTGSWRRLRLGTRGSRLALTQSGQVAEALMAAGGGGAAAAAGKASEGSGGLGIDLV
TVRTDGDGDRTPLRQLGGVGVFAARLRHALLDGEVDLVVHSFKDLPTQPVEGLEVICVPP
REDPRDALCARDGLTLADLPEGARVGTGSPRRAAQLLAARPDLEVVDLRGNVPTRLARVR
GLEVVGVGTDEPVAPSRADAAGDLDAVVLALSGLRRLGLEHCASEVLDLETMLPAPAQGA
LAVEARADEDSAELARAVAALDDEPTRLAVTAERALMARLGAGCAAPVGAWAHLRGGGQE
PREEHAEHGTGWNEEFGGNDTAATRTRQGAGTGQDAGAASGGPRPVVAADRGDERGGTEP
AGAAGPQGSEVSRRSPRVLVLRAVVTSLDGGQEVGCELSTELPEATGGPRTPGDTAAVRA
AEALGVRAAEVLLEDGADQIVDLHANKPRRD
>Q3JDS1|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)|TrEMBL
MSAKTCLRIATRKSLLALWQAEYVADTLRHHYPDLNIELVRMSTQGDKILDTPLAKIGGK
GLFIKELEQGLFSGEADIAVHSMKDVPVDLPENLHIAVICQRGDPRDAFVSNHWQDLDSL
PEGARVGTSSLRRQSQVRERRPDFQVLDLRGNVNTRLAKLDNNEFDAIILAAAGLKRLEL
TQRIRESLAPEVSLPAIGQGAIGIECRKGDTATEELIKVLEHPPTRITIRAERALNARLA
GGCQVPIAGYAELEDERLRLRALVGQPDGGRVIRGETWGMPGEAESLGASLGEDLLRRGA
DKILAEVYSG
>G9V3S4|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 42N|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I6FIH8|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella dysenteriae 225-75|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
GDARTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>H7RF36|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 2553|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>F4E8I1|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus amyloliquefaciens TA208|TrEMBL
MRTIKVGSRRSKLAMTQTKWVINKLKELNPSYNFEIQEIVTKGDRILDVTLSKVGGKGLF
VKEIEQALLHQEIDMAVHSMKDMPAVLPEGLVIGCIPKREDPRDALISKGHQKLDDIKEG
GIIGTSSLRRSAQILAERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKDD
VVSEFLEPDRCLPAVGQGALAIECRESDEELLKLFAQFTDEYTKRTVAAERAFLHAMEGG
CQVPIAGYASVNDRDEVELVGLVASPDGKTIYKETAAGHDPEEIGKRCAAMMSEKGAKAL
IDSVKQELDQDGK
>A7I7P1|hydroxymethylbilane synthase|EC 2.5.1.61|Methanoregula boonei (strain 6A8)|TrEMBL
MPVRIGTRGSRLALAQTAIVIKKIEALGIEVEQKIISTQGDEVTGVPLHEIGKQGVFVRA
LDDAILNNEIDCAVHSMKDIPAIRPSGVFTSAILKRDSPADYLAFTGPVSAVKVVGTSST
RRRAQLLRHDPGLDIRDLRGNVDTRIRKMSEGQYNAVVLAEAGLSRLGIRIPGERLPPEK
FVPSPNQGTIAVVSRADPSIMEVLSSLDHPATRKDVAIERAVMEQVGAGCFTPMGIYCKD
GSLIAEVLSLDGTRAERIEKKIGTLEEARAEGNALRERAGALIEEAYHTLGISL
>B5JSZ9|hydroxymethylbilane synthase|EC 2.5.1.61|gamma proteobacterium HTCC5015|TrEMBL
MKTLRIATRQSPLALWQAEDVAAKLKAHYPDLDIELVKMTTKGDKILDTPLAKIGGKGLF
IKELEVGMLEGRADIAVHSMKDVPVDSEFPEGLHLSVILEREDPRDAFVSNRYNSLDELP
EGAVVGTASLRRQCQVLGRYPHLKTAVLRGSVGTRLGKLDDGQFDAIVLASAGLMRLGLE
ERITAKLPPEISLPAIGQGAVGIECRKDDTELNKLLAPLADRDTTTRLKAERALNARLQG
GCQVPIAGYAELEGDQLSMRGLVGAPDGSKLYTSERRGPRDQAADIGLAVAEDLLSQGAN
AVLSAIGLGGESS
>I5BZM9|hydroxymethylbilane synthase|EC 2.5.1.61|Nitratireductor aquibiodomus RA22|TrEMBL
MQTDVVKIGTRGSALAVAQAAEVRARLMAAHGLPEEAFEIVVISTSGDRIQDRPLSQAGG
KGLFTKEIEEAMLDGRIDLAVHSSKDMPTVLPDGLEISAFLEREDVRDVFIGRSIAKLED
LPQGAKLGTSSLRRQALVLRLRPDLDVGMFRGNVQTRLRKLEEGVAEGTLLALAGLNRLG
MPHIATEVMDPERFPPALGQGAICIESRIGDTRIGPMIAAIHHAETGNALLCERAFLGAL
DGSCRTPIAGLARIDGDTLRFSGLILTPDGRETHEIATEGAVADAVRLGAEAGAEIREKA
GTRFFDSWQ
>F4G170|hydroxymethylbilane synthase|EC 2.5.1.61|Metallosphaera cuprina (strain Ar-4)|TrEMBL
MKVRIAARGSRLSVKQVETVSSYLNSRGYETEFIEVKTRADLFSGTPLHEIGKGVFDKEV
NEAVLIGKADLAVHSMKDLSALPEGLKILATPRRENPSDVLVSDYELQEMPAGSKIGTGS
LRRTNFLKVLRPDLQVINLRGNVDTRIRKYLTREYDGIILAEAGLVRLGINVKRHELDVH
DFTPEANQGIIAIVGRPHLTELLKELNDEATMTVARAEREVVKVIGGGCHSPLGVLFQME
DDRLTGIASYSDGIRRVSASVSVMDSPEAAGQALGRALLKEMKNAGLIS
>F8BB52|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 4a (strain M7)|TrEMBL
MKRKIIVGSRRSKLALTQSNWVINKLKENYPAFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDKTIDFAVHSMKDVPSSLKEGLVIGAIPKRESPLDCFVFNQVNALDELPH
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATKANEAVHFKGLVGNADGSIILEAEQTGANPSEIGNKVAEDLLSKGAD
TIIQELRNI
>C5AW45|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1)|TrEMBL
MALAQTGMVRDRIVAANPGLETEIVVVSTVADRVLDRPLSEIGGKGLFTKELEQALFADE
IDVAVHSMKDVETWLPDGLAIACILERDDPRDAFLSANGANGLADLPPGARVGTSSLRRG
AQVLMHRPDLTIVPLRGNANTRMRKLEAGECDATLLALAGLQRLGMADVARSVLSVEEML
PAVAQGALGIECRAGDDAIRALLAPVACATTTTALDAERGLLAELDGSCRTPIAALAQVK
GDRISLDGLLFLPDGSRHWAVHREGLAADADAIGREAGAELKRAAGDVYFAHLK
>H1FSD1|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurimonas gotlandica GD1|TrEMBL
MNKLVIATRVSDLALWQAYHIKARVEASYPEITVELNKIVSNGDKVLDKPLALIGGKGHF
TKELEDEMLAGNADIAVHSLKDVPTYIPEGLELVAVTQRQDQSDVFLSHKHATLEDLPQG
AVVGTTSLRRRMQLLQQRPDLKVKDLRGNVNTRLRKLSEGQYDAIILAWIGLHRLDLLKD
VPFTQKLSLDMMIPPMGQAALGIEIVCGNAKVREIAESLKDLNTFICTQIERDFISKIGA
GCSAPVACNAVIDDNIITFRVMLGFPDGTNIMQEKVVINVEDSDNLGSELAKKMIDNGAL
ELLKDAEKIAFKDEMPQRL
>Q12S93|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)|TrEMBL
MEAFHMSQHLIRIATRKSPLALWQAEFVKAELERIHPGLSVELVPMTTKGDVLLDTPLAK
VGGKGLFVKELEVAMLEDRADIAVHSMKDVPVDFPEGLGLEIICEREDPRDAFVSNNFAN
LAELPKGAVVGTSSLRRQCQIRAMRPDLIIKDLRGNVGTRLAKLDSGDYDAIILAAAGLI
RLKLISRIASYISPEESLPANGQGAVGIECRTDDARVKALLAPLEHLETRYRVIAERAMN
TRLEGGCQVPIGAYAEIEGDELTLRGLVGNPDGSQIITGQVKGLKSEASQLGEQLAEILL
AQGAKTILDAVYGKA
>G2B201|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli STEC_EH250|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I5ZB05|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC1845|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>B0HL31|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis biovar Antiqua str. B42003004|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>D3H412|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O44:H18 (strain 042 / EAEC)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A0Z3B8|hydroxymethylbilane synthase|EC 2.5.1.61|marine gamma proteobacterium HTCC2080|TrEMBL
MSKLVIATRESPLALWQANYVADRLRALYPELMVELLGMTSRGDQLLDKPLYKVGGKGLF
VKELETALLDGRADIAVHSMKDVPMALPPGLTLGVICEREDPRDALVGISALSELEQGAR
FGTSSLRRACQIRRVRPDLEIGFLRGNVNTRLAKLDAGEFDAIILATAGLVRLGFESRIG
ARIEPEVSLPAGGQGAVGIEYRSDDDRVAELLAPLNDADTAECVTAERAVVRVLDGGCDV
PIASYAVKEGNELWLRALVGSVDGRSVLEAQSRGANAEELGQEVAQALLDGGAAAVLEAV
RG
>C6EG10|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain B / BL21-DE3)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DNLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>H4S5C7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC4F|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H1RE53|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008286|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I0HVE9|hydroxymethylbilane synthase|EC 2.5.1.61|Rubrivivax gelatinosus (strain NBRC 100245 / IL144)|TrEMBL
MSSNTIIATRESRLALWQAEHVRDVLTARFGLAVELLGMTTKGDQILDRALSKVGGKGLF
VKELETALEEGRAHLAVHSLKDVPMDLPSGFALAAIWEREDPRDAWVSNKYENLDALPQG
ACVGTSSLRRVVQLLAHRPDLKIEPLRGNLDTRLRKLDEGGYDAIVLAAAGLKRLGLGAR
IRSLFDTALMIPAAGQGALGIEIREDDARLRELLAQTIHQPTFLACHAERAVSRSLGGSC
SMPLAAFGHWNDGVLTIDAALGHSTELTRPLIKVRVTGTPTDEASARALGEHAAALLREA
GAGDYLPAC
>Q4E9D5|hydroxymethylbilane synthase|EC 2.5.1.61|Wolbachia endosymbiont of Drosophila ananassae|TrEMBL
CVLERLSPCDAFISHKHNSLESLPQQATIATSAIRRKVQLLNFRPDLNIVPLRGNVTTRL
QNQSFDGIILAEAGLIRLEKHHLITEVLPPKVMLSAVGQGAICIQCRRNDVKIIDLLEKI
NNNMSFIGVKSERSFMKTVNGSCFTPLAALAEYVSENMLYLRCMLADGKNIYFTERTSFI
EDAEKMGMDAGLELKSKCL
>F8E2T0|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026)|TrEMBL
MSQNHIPREDSEANPTGAKAAQDLTSQRTLLIGTRRSQLATTQSGHVQAGITEQGWASEL
HIVQTPGDASQASQIPVAQIGVGVFTETLRNALAAKECDVAVHSFKDLPTAPDKRFRIIV
PERVDPREVLVSVDNRLLKDLPEGAKVGTSAPRRVSQLRAVRPDLEILPLRGNIDSRMGR
VGTDLDAVILARAGLERVGQLDRAAESLDPHVIMPAPAQGALAVEVRADDDEAWQAVLPL
EHLPSHLMAAAERAVLATLEAGCSAPVAAHSEWTGSDHTELTISAGVFGMDGTKQLVDTV
KVTFPREFVNAERPQETKPDLDKREQLLARAFDAGSRLGTILLEAGASDLVAEAR
>E4P310|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O83:H1 (strain NRG 857C / AIEC)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H8H5X2|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori ELS37|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIRIVKTTGDKILDAPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCRLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEAITKEKRGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>H2G5P4|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain 31A)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>I0IB92|hydroxymethylbilane synthase|EC 2.5.1.61|Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)|TrEMBL
MLASRRSPLARVQTEAVAAALREAWPGLEPAFLWQRSTGDRVLDRPLADVGGKGLFVKEL
DAAVCSGAAAAAVHSLKDVPTRLAPGLVIAATPRRAPVEDVLLCGAGAAGFSALPAGATL
GTSSPRRAAQALRANPRLRVVLLRGNVGSRRAAVGLGEPGDGSPTRCDATVLARAGLERL
GVSVEAPGHAVLPPEESLPAAGQGAVAVVCREDDAATRERLAPLDDPPTAAAVAAERALV
HRLGADCHSPVAVLAAPEAAPGSPGRWRLRARVLSTDGRRCLAAERTCDAGRLMAAAEDA
AAELLGAGAAALLAEAASA
>E8BI76|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 556150-1|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I6E5H6|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella sonnei 3233-85|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQNAKQMGISLAEELLNNGAREILAEVYNGDAPA
>C6NT64|hydroxymethylbilane synthase|EC 2.5.1.61|Acidithiobacillus caldus ATCC 51756|TrEMBL
MPTHHRQEMSRTSSVTPLRIGTRASPLALWQAEHVRAGLLRAHPEIPVEIVPMTTQGDRM
LAVPLHEIGGKGLFVKEIEAALLEGTVDLAVHSMKDVPAQQPEGLEIAAILAREDVRDAW
VSNTFARPEDLPQGGRVGSSSLRRRAQLLHRLPQTVVLDLRGNVATRLRKLDAGDYDGIV
LAAAGLKRLGLLERIRHYLEPELSLPAVGQGAIGVEIRSDDARTRTLLKPLNDPTTSRCV
GAERHMNRLLGGDCRLPVAALAEADGTGLRLRGLVASPDGRELLRAEAVGSLAHSVGEQV
AQALLAQGAQHIIDEVKRA
>I4K8L2|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas fluorescens SS101|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLKVSLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTFASLDELP
LGSIVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVEDSLPAGGQGAVGIECRTADSEIHALLKPLDHADTEVRVTAERALNKHLNG
GCQVPIACYAVLEGENLWLRGLVGDPDGGNLLTAEVRGPQRDATALGIQVAEALLEKGAG
AILQKVYGEAGPQ
>H5CDT5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC9C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D1C0P9|hydroxymethylbilane synthase|EC 2.5.1.61|Xylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07)|TrEMBL
MGDVTAPLRLGTRASLLATTQSGLVAKRLEELTGRPVELVHIRTDGDVLTGSLASLGGTG
VFVAALREALLDDRCDVAVHSLKDLPTAAVEGLTFVTPEREDPRDALCARDGLTLDTLPR
GARIGTGSPRRAAQLRAARPDLDVVDIRGNVDTRLKRALGPDADLDAVVLACSGLARLGR
TDTVTQALDPAVVAPAPGQGALAVEARTTDLAPGGPLAAAFAALDHRATRLSVTAERAVL
ARLEAGCAAPVGALARVDEGQLTLTAVVARVDGTEKLRHRASVALGAISGDDDAARDLGV
RVAEALLADGAADLAPLAATAQRPTTTPDPALADPTEAGAPGS
>B7KWK1|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacterium chloromethanicum (strain CM4 / NCIMB 13688)|TrEMBL
MSLSRALRIGTRGSPMALAQTGMVRDRIVAANPGLETEIVVVSTVADRVLDRPLSEIGGK
GLFTKELEQALFADEIDVAVHSMKDVETWLPDGLAIACILERDDPRDAFLSANGANGLAD
LPPGARVGTSSLRRGAQVLMHRPDLTIVPLRGNANTRMRKLEAGECDATLLALAGLQRLG
MEDVARSVLSVEEMLPAVAQGALGIECRAGDDAIRALLAPVACATTTTALDAERGLLAEL
DGSCRTPIAALAQVKGDRISLDGLLFLPDGSRHWEVHREGLAADADAIGRDAGAELKRAA
GDVYFAHLK
>D0JTN2|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis (strain D182038)|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>D3MHC0|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes J165|TrEMBL
MPLWCRRPAELSVNLSDCRLESASVLSATIGNMSAIRLGTRASTLATTQSEMVAGLLRSE
GLDVNLTTITTHGDTSTASLAAMGGIGVFASAIRAALLEGEADIAVHSFKDLPTGRPLGL
AIGAVPARADPRDALVARDGLTLHDLPQEASVGTGSPRRAAQLLAVRPDLTIVDIRGNVD
TRLGRVKGLGRYAKNGGKEDLDAVVLAASGLARLGHSGAVTEFLDPSVVLPAPAQGALAV
ECRTADSRHGKLAKALARIDDRRTRLAATAERAVLSHLEAGCAAPIGALAQLKPVSGKSL
QVLTLDVVVAAVDGSRTVREQVSVELPAEVEPALAAAHTLGVTAAEELLDDGAADVADLK
ASGSTR
>D3MHC0|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes J165|TrEMBL
MPLWCRRPAELSVNLSDCRLESASVLSATIGNMSAIRLGTRASTLATTQSEMVAGLLRSE
GLDVNLTTITTHGDTSTASLAAMGGIGVFASAIRAALLEGEADIAVHSFKDLPTGRPLGL
AIGAVPARADPRDALVARDGLTLHDLPQEASVGTGSPRRAAQLLAVRPDLTIVDIRGNVD
TRLGRVKGLGRYAKNGGKEDLDAVVLAASGLARLGHSGAVTEFLDPSVVLPAPAQGALAV
ECRTADSRHGKLAKALARIDDRRTRLAATAERAVLSHLEAGCAAPIGALAQLKPVSGKSL
QVLTLDVVVAAVDGSRTVREQVSVELPAEVEPALAAAHTLGVTAAEELLDDGAADVADLK
ASGSTR
>I2AWX8|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella noatunensis subsp. orientalis (strain Toba 04)|TrEMBL
MKQIVIASRESKLALWQTNYVKDRIQQELNIPCQISTMKTQGDIILDKPLNKIGGKALFM
KELEIAMLNDKADIAVHSLKDVPYELPEGFCLASFMPREDPRDAFVSNKYISIDDLPRGA
IVGTSSLRRKAQLFHYRDDLIIRDLRGNIQTRLSKLDNGEYDAIILASAGLIRLGLNERI
IQLIPVEISLPAVGQGIVVIEALDKSGEILEKLQKLNCGDSFCVATAERAFNQELKGGCH
VAIGAYAELQGNQITLTGMVASSNGKNILKRKLMGDDPIKLGKLLAQEMIELGAYTILEK
>D7UYY2|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria grayi DSM 20601|TrEMBL
MKSQIIVGSRRSKLALVQTNWVINELKKHYPTIDFRIEEMVTKGDKILDVTLSKVGGKGL
FVSEVEQALVDKHIDFAVHSMKDVPAVIEEGLTIAAIPERESANDVFVFKEVHDFGDLPT
QAIIGTSSLRRASQILAERPDLQIKFIRGNIDTRLRKLREEDFDAIILAQAGLSRMGWLE
DDSLRIQTIPETICLPAVGQGALAIECREEDNDTKDILRSIHHAITANCVAAERAFLKTL
NGGCEIPIAGYATQSGSKVSFKGLVGTPDGKTIWEAERVGEDADQIGTEAANELLEKGAG
ALIASLRDENV
>D3DZ46|hydroxymethylbilane synthase|EC 2.5.1.61|Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / M1)|TrEMBL
MIVGTRGSKLALVQTDYIRQCLYNITGEEVEKNIIKTKGDKITNSQLYNMDSKGLFTREL
DNALLDEEVDFAVHSLKDVPTELNEDLEIVAVPIRESPNEVLISNYSWSELEEGSTLGTS
SLRREAFCKHHNKDFELKPIRGNVETRIEKVMDGQVDATIMAEAGLNRLGLQKYIKAKFP
TDYIMPAAGQGALAVMTRKDSEHKETIRKLNHYFSHQEVLAEKTILEEIGVGCQWPIGAI
SGIKNNQLELKSILLDKNGEILYQKTLSGSIREAKEMGVQIGKEMIEFI
>B9KIR4|hydroxymethylbilane synthase|EC 2.5.1.61|Anaplasma marginale (strain Florida)|TrEMBL
MYAPVVRLGTRGSTLALIQAEEVKAAIAAHFPEVRVDVTKIKTSGDVKVDRPLCDIGGKG
LFIKEIEEALLANKIDIAVHSAKDVPGFYSENLDMPCVLKRRSPMDVFISVKYKSLNSLP
AGAKIGTSSIRRKVQLLAFRPDLEITPMRGNVDTRIAKVQSGECDGIVLAEAGVDRISAR
AKITEVLHPDVMLGAVGQGAICVQCRKSDEGIVRMLAKLNDHESFTAVLAERSFMKAVNG
SCHTPLAAMARYVDSGLMSMKCMLAHDSRTMVSAERTFPERDAESVGFEMGVMLKDELRL
RGV
>H7UCF6|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 1961|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>E6LJU3|hydroxymethylbilane synthase|EC 2.5.1.61|Eubacterium saburreum DSM 3986|TrEMBL
MFHKEIIRIGTRKSALALAQTKLVGDAVKNSFPHIKIEYVPMNTIGDKRLDISLQEIGGK
GLFTKELEEALIKGDIDLAIHSAKDLPLEFDNRLKLMPVLKRGAVRDVLVVKNDCPVDLQ
IKDLPRGFRIGTSSKRRSEQAMLLNHNIKIVPIRGNVLTRIGKIFSGDTDGVILARAGLD
RLLADTNCAGECDKILQKVNITDIKETDILPAPAQGILCGQYASDYISEVLKKIQDEDCN
ILFNAERKYLSVLEADCHTSAGIYIKKDRDNYSIKAYFEGKYQIAYSDSKGLFDMVENTA
NKLKRKNVK
>A9MY57|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)|TrEMBL
MATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVHSMKDVPV
AFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRL
DDARTQALLAPLNHSQTALRVTAERAMNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPD
GSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA
>H8NL45|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia typhi str. B9991CWPP|TrEMBL
MINSIRIGTRNSTLALIQTNLVIAQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGRIPVDLVIAAVLEREDPRDVLVCLNYKSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDATILSYAGLKRLNAFN
KKYCHLIEYSQILPCVGQGVIAVEIRKDDNAMFNICNQINHIPTFELIKPERAFLEHLDA
NCSTPIGAYSQYLDAYNIQTDFMLGKLDCNKIIFQTEITNINTSRECGIKAAKMMLAQQ
>I4F411|hydroxymethylbilane synthase|EC 2.5.1.61|Modestobacter marinus|TrEMBL
MTDLRTATLRLGTRASQLALTQSQLVADALSSSSGVPVELVHVSTYGDRSTEAIAQLGGT
GVFVSALRDALHAGTVDLAVHSFKDLPTAPTPGLTVAAVPAREDPRDVLVARDGLTLGEL
PPGARIGTGAPRRMAQLRALGLGLEIVPIRGNVDTRMGKVASGELDAVVLARAGLARIGR
LSAVTETLDPIQVLPAPAQGALAVECRSDDTRVRELLAALDDPAARACVAAERAVLAALE
AGCSAPVAAHAELTEAEDGSAELWLRASVTAIDGSDSVRDSVSGPAAEAESLGRRLAAEL
LDRDAAALMAASR
>I4F411|hydroxymethylbilane synthase|EC 2.5.1.61|Modestobacter marinus|TrEMBL
MTDLRTATLRLGTRASQLALTQSQLVADALSSSSGVPVELVHVSTYGDRSTEAIAQLGGT
GVFVSALRDALHAGTVDLAVHSFKDLPTAPTPGLTVAAVPAREDPRDVLVARDGLTLGEL
PPGARIGTGAPRRMAQLRALGLGLEIVPIRGNVDTRMGKVASGELDAVVLARAGLARIGR
LSAVTETLDPIQVLPAPAQGALAVECRSDDTRVRELLAALDDPAARACVAAERAVLAALE
AGCSAPVAAHAELTEAEDGSAELWLRASVTAIDGSDSVRDSVSGPAAEAESLGRRLAAEL
LDRDAAALMAASR
>E7ITC6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli OK1180|TrEMBL
MVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLG
LVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGT
RLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRE
LLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRG
ERRGAPQNAEQMGISLAEELLNNGAREILAEVYNGDAPA
>B4ABG2|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Newport str. SL317|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKY
HSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAG
LKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEE
LLENGARAILTEVYNGETPA
>I5ERE5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 93-001|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E1RNP7|hydroxymethylbilane synthase|EC 2.5.1.61|Xylella fastidiosa (strain GB514)|TrEMBL
MPLLRIATRKSLLAMWQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIG
ARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQR
MTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRKCVIAERTMNRALHGSC
HVPVGAYASYEVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAEL
LAATA
>C5UPI2|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum E1 str. 'BoNT E Beluga'|TrEMBL
MNELIIATRKSKLAQVQTEIIMSELKSKFNIDSKKLLIVTEGDRKLDVSLNKIGGKGLFV
KDIELALLNKEAHAAVHSMKDVPFEVSSEFEITAITGREDIRDVFISNGDISFKDIKKGA
KVGTSSIRRAAQLKLLRSDLEIVPIRGNVQTRLKKMEEQNLDGIVLAAAGLKRLGDKNLI
TDYFDPKEFLPAVSQGALGIECLKDGDANKYFEALIDAEATLTVEAERSFMKELQGDCHS
LIGAYSEIKGDDLYMIGIYDIGGKIVKKDILGCKTNNIELGKKLAQKILG
>F4CZS0|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)|TrEMBL
MTPVLRIGTRPSALAMAQSGQIADRLRAAGHTVELVPVSTVGDRSGAPVAELGVGVFVSA
VRDAVASGEVDVAIHSYKDLPTAPDPRLTLVAVPGREDPRDALVARDGKVLGELPAGSRV
GTGSARRTAQLQALGLGLEVVPIRGNVDTRIGKVTSGELDGVIVAAAGLRRLGRIGEATE
LLEPVQMLPAPAQGALAVECRAGVPGSTEHGLALALTALLDDPAARAAVTAERAVLASLE
AGCTAPIGALADVVSDLDDAGRVVDRLSLRAVVGTADGALLRASVTGDIDDAEKLGAALA
AELLDMGADTLPGTAGRQENRWIGSSE
>B1Y160|hydroxymethylbilane synthase|EC 2.5.1.61|Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6)|TrEMBL
MRDNAGMSTLPQPCIIATRESRLALWQAEHVRDLLQRRHGAVVELLGMTTRGDQILDRAL
SKVGGKGLFVKELEVALEEDRAQLAVHSLKDVPMELPEGFVLAAVLEREDPRDAWVSNHY
DDVASLPQGARVGTSSLRRIVQLKAVRPDLEIHALRGNLDTRLRKLDEGLYDGIVLAAAG
LKRLGLAQRIRSVIDPAVMLPAAGQGALGIEVRADASALREALAAMTDAPTWLAVHAERA
VSRALGGSCSMPLAAFAQWQGAQLHLEARLGHPEDASVALIVASAEAAVTDTAGAEALGL
AVVARLRAGGGEALLAALPVAS
>Q2CDN2|hydroxymethylbilane synthase|EC 2.5.1.61|Oceanicola granulosus HTCC2516|TrEMBL
MTDTPTPDRPLKIGTRGSPLALAQAHETRDRLAAAHGLPGEAFEVVVIRTTGDRVVDRPL
KEIGGKGLFTKEIEEAMLSGAIDIAVHSMKDMPVAQPEGLVLDCYLPREDPRDAFVSLLH
AGIKALPDGATVGTSSLRRKAQLLHRRPDLHVVEFRGNVQTRLRKLESGVAVATFLAVAG
LNRLGADDVPQAPIAPEDMLPAVAQGAIGIERRASDEGLGEMLAAIHDRATGERLAAERA
FLAALDGSCETPIAGLAELIGDGRLRLRGEILAHDGSRCLADEAEAQIADGAALGTDMAR
RLLAQAGPGFFDS
>A6XZR2|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae AM-19226|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSKIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>E1D8M5|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio parahaemolyticus AQ4037|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSNINEL
PQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EDRIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEVRGHRKDGEALGIQLANELLDSGA
RDILTKLYADHD
>D9Q682|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium pseudotuberculosis (strain 1002)|TrEMBL
MTFTIGTRGSLLATTQSGHVRDALISQGYSAELSIVTTPGDVNMAPVERIGVGVFTQALR
DVLVKGGCDIAVHSFKDLPTQRDPRFHLIVPERADARDCLVARDGLTLAELPQGARIGTG
APRRISQIKALRPDVECVPLRGNIDTRMGKVFSGELDAVVLAYAGLSRVGRGDEATEVFN
PERFLPAPAQGALAIECRVDDAAAVAAINAIRNAEDETCALAERVVLNRLEAGCTAPVAA
HSVIIEQELQVTGAVISLDGSKVLRATMTGGLSEAVAIGEKVAAKLIQDGAAELLS
>G4VRL5|hydroxymethylbilane synthase|EC 2.5.1.61|Schistosoma mansoni|TrEMBL
MLGSSPRNVVRVGSRRSNLALLQTGMAVNLLQKQNPHILFEVVEMATVGDKILDVSLSKI
GDKSLFTKELENALLSGEVDLVVHSLKDVPSTLPSGLVLGCVFARVSPEDVVLMAPHYRG
RKLSDLPIGSTVGTSAVRRVATLTRKYPHLKFVSIRGNLNTRLAKLDTPPASKDNCCSGN
PSPSYDAIILAKAGVERMGWSHRIDQVLTDSFYAVSQGALACECRLVDNFIMDLLSHIHD
ESAALTTIAERSLMRQLDGGCSIPIGVRSDLVLKGDLNYYQLTLHANILSVDGGKSIERS
ASVVFPDKMPINDCVESSCKLVQKSGSYDDVSTNTPIIKNKGTSLTSPTKDELKAALDAT
SIFMGVIVTPSSEMSRLRMAIAQSLGCTVAKSLLLSGADEILYEIRSQSSG
>D5B591|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis (strain Z176003)|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>D9RL52|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain JKD6008)|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>I4BDT1|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium chubuense NBB4|TrEMBL
MIRIGTRGSLLATTQAGVIRDALIAAGHAAELVIVSTEGDRSDAPIADIGVGVFTAALRE
AIADGTVDMAVHSYKDLPTATDPRFVIAAIPVREDPRDALVARDGLVLGELPAGSVIGTS
SPRRVAQLKALGLGLEIRPLRGNLDTRLSRVSSGDLDAVVVARAGLARIGRLDAVTEALE
PVQMLPAPAQGALAVECRAGDTGLATLLAELDDADSRAAVTAERALLAELEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVATLDGSDVIRASGIGTPGRARELGLSVAAELFELGA
RDLLDERGRDT
>I4BDT1|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium chubuense NBB4|TrEMBL
MIRIGTRGSLLATTQAGVIRDALIAAGHAAELVIVSTEGDRSDAPIADIGVGVFTAALRE
AIADGTVDMAVHSYKDLPTATDPRFVIAAIPVREDPRDALVARDGLVLGELPAGSVIGTS
SPRRVAQLKALGLGLEIRPLRGNLDTRLSRVSSGDLDAVVVARAGLARIGRLDAVTEALE
PVQMLPAPAQGALAVECRAGDTGLATLLAELDDADSRAAVTAERALLAELEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVATLDGSDVIRASGIGTPGRARELGLSVAAELFELGA
RDLLDERGRDT
>H1YY67|hydroxymethylbilane synthase|EC 2.5.1.61|Methanoplanus limicola DSM 2279|TrEMBL
MPLTAGTRGSKLALVQTEKVCAMLSELGIETEIKIIKTEGDANTDVPLHQVGGQGIFVRA
LDDAITKGEVDFAVHSMKDIPAARPKGVRTCAILKRDSPADFLVHECPLEEIKVVGTSST
RRRAQLMRGNLNAEIKELRGNVDTRLRKLKEGEYDAIVLAEAGMQRLGLDLPGTRLLPQW
YVPSPNQGTIAVVCREDDALAAQFEQINHKPTEKDTAIERAVMEEIGGGCYTPQGVYCEN
GFLIAEVLSLDGSRYERIEDAGGSEEEARFIGQKLKGLAFDLIEEAKESLGLKY
>E5TAK7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CGS00|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>G1YGF3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli STEC_B2F1|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>G2CS49|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli STEC_S1191|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F9K6P5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21201|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H8K798|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia australis (strain Cutlack)|TrEMBL
MINSIRIGTRNSPLALIQTNLVIQQIKQFFPDINCAIVPIITSGDLIQKKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEELVIAAVLEREDPRDVFVCLNYKSIEELQQ
HSVIGSSAVRRKAFIQKIRPDLKVTIFRGNVNSRIKKLMTGEVDATILAYAGLKRLGAFN
PEYCHLIEYSQMLPCVGQGVIAVEIRQNDNSMLEICNQINHLPTCELIKPERAFLEYLDA
NCRTPIGAYSQYLDADNIQTDFMLGNLDCSKITFHTEITNIKTSKEGGIKAAKMMLNQLK
K
>I6BB21|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri K-1770|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLCALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGEAPA
>G9F081|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium sporogenes PA 3679|TrEMBL
MNFIIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPKREDVRDAFISLDNIKFKDLREGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
>Q9W0G4|hydroxymethylbilane synthase|EC 2.5.1.61|Drosophila melanogaster|TrEMBL
MSAQEKVIRVGSRKSELALIQTKHVIGRLQKLYPKQKFEIHTMSTFGDRVLNVSLPKIGE
KSLFTRDLEDALRNGGVDFVVHSLKDLPTALPTGMAIGAVLEREDARDALVLRENFKGHT
IASLPKGSVIGTSSLRRTAQIRRMYPHLTVCDIRGNLNTRLAKLDAADSKFSGIILAQAG
LVRMGWMSRISQVLEPTDLLYAVGQGALAVECRANDDQVLAMLQKLMCLNTTCRILAERS
FLKTLGGGCSAPVAVWSNLKGEPLNGNSQEVGLSLTGAVWSLDGAIEIRNHLACALNEQK
LEGDQRKRGAQEATSQLQEETSSSCDSPPATKRARNGNDSSGSDSNSSSPRQQGSPPVIC
EDAAACAALSGYTVDQLSDLASHCPVLSNNNAVGPTGVSGGGDADTNNVNTTPRQCPLRL
VGGQEVMGQCPVPHNQAMVPAKCPVAHADSGDSFSAKSGSGGESATTAHCPLQMPVGQDF
MGECPYVNNDVKVSFAQAGKCPVTGGVAGASASILPTPPSSRASNASSAGDEVDNVATSS
KCPFAAMHQGSGLEAPAKDNGNAATAKCPFLQKTVQMFDYADEEQPTPQHSVLIEDVENL
FCGLYQHACHSRGIYEKANQLGKTLAEDLIKRGALDVMKVAQAEIHGKVASS
>D5BTX1|hydroxymethylbilane synthase|EC 2.5.1.61|Puniceispirillum marinum (strain IMCC1322)|TrEMBL
MVSWRKQMTLDFLAFFWAMQAGVGALDMAVMKPDASYFFATPLVLASRASTLAMAQAELV
RVALKPVASRIEPFTTKGDLILDRPLVEVGGKGVFIKELERSLLAGESDAAVHSMKDMES
DFAAGTMIGAVLPREDRRDALVGSYADLDALPDGAIVGTSSVRRRALLLHHRPDLRIKLL
RGNINKRIAKLNQGDYDAIILAVAGLKRLKLSLDYTPLDEKLMPTAAAQGALAVQLCDPS
LAQGEKAIRQQAVFDAISPLACVNSTIEVTAERAMLAHLDGSCHTPIAASARFVDDKTLR
LDGMVLSSDGSAAFRRTMTASKDEAVALGIKVGVALLDDAGGRGFLA
>B5MTI0|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Saintpaul str. SARA29|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKY
HSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAG
LKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEE
LLENGARAILTEVYNGETPA
>E2Q6W5|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)|TrEMBL
MGVTVATYFVGSRASNLAKAQVREYLRPLRERFPEITFTHRVILEGGDRDRTSTLSAVSA
VNGGSAFSSAQEAALSRGDVDVVVHSLKDLPTANPAGLVLLPPPGREDVRDALCGSTLAG
LRKGARVGTGAPRRVAQLLAVRPDLVVVPIRGNVPPRLKKIETMGLDAVVLAVAGLRRLG
LDDAIGDVLPLDLFPPSPGQGALGIQVRTDDHSAPLRDLLSTVGDASADAAVRAERALLA
ELHGGCSVPVGAYAEPLPNGELSLAGQVTSLDGRERVAGTLTGPATEPEKLGASLAALLI
DRGAHAILDRVRSTHGSRHYPADHASGSRARRS
>B6C3W5|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrosococcus oceani AFC27|TrEMBL
MVFIMSAKTCLRIATRKSLLALWQAEYVADTLRHHYPDLNIELVRMSTQGDKILDTPLAK
IGGKGLFIKELEQGLFSGEADIAVHSMKDVPVDLPENLHIAVICQRGDPRDAFVSNHWQD
LDSLPEGARVGTSSLRRQSQVRERRPDFQVLDLRGNVNTRLAKLDNNEFDAIILAAAGLK
RLELTQRIRESLAPEVSLPAIGQGAIGIECRKGDTATEELIKVLEHPPTRITIRAERALN
ARLAGGCQVPIAGYAELEDERLRLRALVGQPDGGRVIRGETWGMPGEAESLGASLGEDLL
RRGADKILAEVYSG
>F0FLE0|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK405|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKKLHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRQLLATVQDEKTAAEVAVERVVLAQM
NADCTFPIAAFAQKNGQDYQLEAMLAKEDGQCVFVSLKGQDGQQLAEQAVRQLADKGAVG
MPWLKK
>C9YZC4|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces scabies (strain 87.22)|TrEMBL
MSEPHNRALRLGTRRSTLAMSQSRQVADAVRRLTGRPVELVEITTYGDVSREQLAQIGGT
GVFVAALREALLRGEVDFAVHSLKDLPTTYPDELTLAAVPVRADARDVLVARDGLTFEQL
PAGARVGTGSSRRMAQLNAYARGHGLTIETVPIRGNVDTRIGYVRKGELDAVVLAAAGLS
RIGRIDEVTDFLSVDTVLPAPGQGALAIECAAADAELIAALAGLDDPDTRAAVTAERSLL
AALEAGCSAPVGAFADLLADGQTVKEMRLRGVVGTTDGSTLVQLSTTGPVPETYDQAMAL
GRELAAEMLAKGAAGLMGERAH
>C0BL56|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacteria bacterium MS024-3C|TrEMBL
MAKTLRIGTRDSALAMWQAKTVQSQLAAHGIASELVPVKSLGDLKLDQPLYELGVTGVFT
KTLDLALLAGEIDLAVHSYKDVPTVLAKGLSTAAVLKRASTADVLVHKSPDFTTSGLQIA
TSSLRRKAQWLAKYPEHQLVDIRGNVQTRLEKLANNSWGGAIFAAAGLARLDLLPENAMR
LDWMVPAPAQGAMVVVAQSAHTVLLEELSVLNDSQTALCTQIEREFLNELEGGCTAPIGA
LCTTTQDQLHFIGVLHSLDGKQHIETNTFVPLDQAPGYGRKMAQKILSQGGKALMAEIKK
ALS
>Q0FKY5|hydroxymethylbilane synthase|EC 2.5.1.61|Pelagibaca bermudensis HTCC2601|TrEMBL
MMTLLPSPAAPLKIGTRGSPLALAQAHETRDRLAAAFDLPQDAFEIVVIKTTGDDRAMIA
ADRPLKEIGNKGLFTKEIEEQLLSGGIDIAVHSMKDMPTEQPEGLVLDCYLPREDERDAF
ISPGHAGLAALPEGTVVGTSSLRRRAQLLNRRPDLQVVEFRGNVQTRLKKLEDGVAAATF
LAMAGLRRMDMTDIPMTAMSPDDMLPAIAQGAIGIERRSDDSRTGDMLAAIHDTDTATRL
AAERTFLAALDGSCETPIAGLAELDGDRLRLRGEILAPDGSASHAGELSGPAADGPAMGR
ALAEELLARAGPDFFAWRG
>H7YRN6|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 23357|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIVSLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFITKGAKELL
KKAESMI
>G2IUI7|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudogulbenkiania sp. (strain NH8B)|TrEMBL
MDKIVIASRESKLAMWQAEHIKARLEQLYPQLAVEILGMTTQGDQILDKTLSKIGGKGLF
VKELELALQEGRADLAVHSIKDVPMNLPEGFALAAICEREDPRDAFVSNTYASLSELPDG
AVVGTSSLRRESQLRARFPRLTIKPLRGNVQTRLRKLDDGEFDAIILAAAGLKRLELTER
IRCELAPSESLPAVGQGALGIEIRADRADLMQLLAPLDHADTHACVSAERSLSRVLGGSC
QIPLGGFATLSDDVITLGGFVAHPDGSVMLTASASAPREYADALGRAVAQKLLDAGAAPL
IQAVIDEGQGR
>F4BYP6|hydroxymethylbilane synthase|EC 2.5.1.61|Methanosaeta concilii (strain ATCC 5969 / DSM 3671 / JCM 10134 / NBRC 103675 / OCM 69 / GP-6)|TrEMBL
MGTRGSPLALRQTQIVQERLKGLGIQTQLCRVKTSGDVFLDKPLHQLTGFGVFVAEIDER
MLSGKIDLAVHSMKDLPTKRPEELIVSAVLKRDSPYDVLLCREKSVKSIEELDQGARVGT
SSMRRMAQLLRARPDLNILSLRGNLQTRLSKLERGDYDAIVLAEAGLERMGYHPDYVRLD
GERFVPSANQGTIIVVAKAGSEAEACSRALDDAHARSETMIERKIMETVGGGCVVPMAVH
ALVQKGEARVLAEVLSPDGKRFVRLEERISLVQNHLAVAEDMGERLMRMGGRELVDEAVK
FFGNR
>A0JYM6|hydroxymethylbilane synthase|EC 2.5.1.61|Arthrobacter sp. (strain FB24)|TrEMBL
MTVRIGTRASKLALTQTQQTADQLAAIGGFPVELVHIRTDGDVLTGSLSQMGGTGVFVAA
LREALLRDDCDVAVHSLKDLPTGAAPGLNLAATPKRVDVRDVLCARDGFKLADLPQGARV
GTGSPRRAAQLRAARPDLDVVDIRGNVDTRLGRVPGLPGNTTDAVVLGKSCDLDAVVLAA
AGLERIGRLDTVSEYLETDVMLPAAGQGSLAIECRTADAPRRTGSTEGSQGPLAQALAAL
DDTDTRLAVTAERALLARLEAGCAAPVGAYAFRKGSMLYLEAAVCAVDGSATVRDKRATD
GLTEVGATLLGIELAEALLAAGAADIADLAAS
>E7JAX9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli OK1357|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H4H1Y1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1500|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>D3RMK0|hydroxymethylbilane synthase|EC 2.5.1.61|Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / D)|TrEMBL
MSNSIRIATRKSPLAMWQAEHVTARLKALHPGLTVEIIGMTTKGDQLLDSPLSKVGGKGL
FVKELEQGMLAGEADIAVHSMKDVPVEFPEGLHLAVIMERENPYDAFVSNTYANLAELPE
GACVGTSSLRRQCQLADRRPDLRIEPLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFES
RIRDCIDPVDSLPAIGQGAIGIECRVDDERVHQLIAPLADRDTTDRVLAERAMNARLNGG
CQVPIGGHAVLDGDRLILKGLVGTTDGSRILRAEASGPRAEAEAIGVRVADDLLGQGADA
ILSALMGH
>I2XPG5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 3.3884|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q6N9N5|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)|TrEMBL
MVKFPVRIGTRKSVMALAQTEDIAKQLSAAASELDPQIIKFETVGDSDQISKLLPHGGKG
GAFVAEIRAAMLRGELHCAMHSLKDMPANEETPGLIVAATLARDPACDSLVLRKGLTLEE
LKKSRGKGYTIGTNAVRRAAYAKRLFPEVEVIHFRGAADSRMRKLDNREKQRMPDGSEVG
PADALIMARAGIERVGFVDRIAHDFTPEEMLPAAGQGIVAVECPVHEWKTRQYLALIDNH
QSRLCCDAEREVLWVLNGHCNSPIAAHSVITGDEMTLRASVLDLEGGMFIEAARTGPANR
PRELGRTVGLELLDKGAAAVIEKTRPE
>C1DJ46|hydroxymethylbilane synthase|EC 2.5.1.61|Azotobacter vinelandii (strain DJ / ATCC BAA-1303)|TrEMBL
MPMPREIRIATRKSALALWQAEYVKARLEQAHPGLAVSLVPMVSRGDKLLDAPLAKIGGK
GLFVKELETALLENAADIAVHSMKDVPMEFPEGLGLYCICEREDPRDAFVSNAFASLDEL
PAGSLIGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGF
EGRIRSRIAIADSLPAGGQGAVGIECRSADREIQALLAPLDHAPTALRVGAERALNKRLN
GGCQVPIACYAELEDGQLWLRGLVGQPDGRLLLRAEARAPADEAEALGVRVAEALLAQGA
QRILAAVYGEGERP
>C2I1U6|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae TM 11079-80|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDAILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDHIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>I5U6E3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4421|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>B1V7A1|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium perfringens D str. JGS1721|TrEMBL
MELIIATRKSKLAQVQTEKVMELLKEKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVK
EIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGAR
IGTSSIRRAEQLKLFRDDLEIVPIRGNVQTRIKKITEENLDGIILAAAGLKRLGMEDVIS
DYFDPKVFLPAIGQGALGIECLKGGEFNDYFKALDSKEVRTTVDAERSFMKVLNGGCHSL
IGAYSEVKDNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILEEV
>F0GYK2|hydroxymethylbilane synthase|EC 2.5.1.61|Anaerococcus hydrogenalis ACS-025-V-Sch4|TrEMBL
MIKIGSRASKLALIQANMVKDILEKEGLEAQIVEISTKGDRIRDRKIDQLNSKGVFVREI
EEKLLDKTIDLAVHSLKDMPSQIDDRLIFTPPLKGEDPRDCFVGKDIFKKMDDLNNALVG
TGSNRRVCQGKNYFTNIKFKAIRGNVETRIKKVQSENLDGVILAKSGLIRAGLDGEINFD
LDPHIFTPSPCQGILGIEIRKEDKKLFEIFKKNSDEKTLFRMETERAFQKELGADCSTPM
GIFTEIDHDKITLTGSMAFDKDDRINYEKVSGNISDRINLAQKLARTLKKKSYKKIILAG
AGIGSKNNITLAVKKALDEADVIIYDRLLNQEILDPYRNKDLYYVGKSMGDHVLSQDDIN
KLMVDKAKTGKKVVRLKGGDPYVFGRGSEEALFIKENGLEFETLPGLTSGIVCLNTAGIP
ASHRNMATSISFITGHRSENQNEDFKKYAKLPGTLVFYMGLKNLPNIIKDLIDGGIKKDK
KIAIISNGSSPKQKVYSSNVEKVLEEIDLEKIKRPAIIVVSDTVGLREYLNYFESKNFGK
KIALTRDYESTIKDKEKLEGLGFDVKIVPTIKILEKNTDLLEEKFKDFSYDYLVFTSKNA
VKIFFDKLIENHDIRDIGKVKIAAIGEKTKKEIEKYNLKVDIVPRNFVGENLLDQMEKYV
KKGEKIFFPHSNLSRKKIIEGLGKMGDLDEIEIYDNIRAEKEDIDLDFDGVIFTSSSCVN
NFVEIYGKDPLKNTKIYSIGQITSQTIKNHGLEVYKESKKQSVDSLIERIVEDYENEKN
>D9PJ11|hydroxymethylbilane synthase|EC 2.5.1.61|sediment metagenome|TrEMBL
MYVDQLLNLWGLMANPIKIGTRGSKLALWQAGWVKSILETDHASLRIELVSIKTKGDKIL
DVPLARVGGKGLFVKEIEEALMDRRVDIAVHSMKDMPSEIPPELSIGAIPKRETPKDVLI
SKSGLSLLDLPWGARIGTASLRRAAQIRHLRPDILVLPVRGNLDTRLKKLEGDNLDAIVL
AAAGVRRLHFEDRITQYLDEYQMVPAVGQGALCIEIR
>H5DB15|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC9E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H3YWD9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-122|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E8XIP4|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella typhimurium (strain 4/74)|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHS
LDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELL
ENGARAILTEVYNGETPA
>B1FY93|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia graminis C4D1M|TrEMBL
MWQAEHVRCALHKLYPSCDVKILGMTTRGDQILDRTLSKVGGKGLFVKELEAALADGRAD
LAVHSLKDVPMELPAGFALSTIMEREDPRDALVSNDYDSLAALPAGAVVGTSSLRREAML
RMRYPHLEVRPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLEGRIRALLDPEDSLPAA
GQGALGIEIRSDRAELAAWLAPLHHEHTAAAVEAERMVSRVLGGSCEVPLAAYATWHDGA
LHLRGIVATPDGQRVLSAQASAPAPTTERAIALGREVANALEQQGAMDIVRALSTASAVD
GAAASSGNGAANSAVSGD
>I5KS17|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA31|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>D7BI20|hydroxymethylbilane synthase|EC 2.5.1.61|Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2)|TrEMBL
MRVIVIGTRGSLLALAQTRWVVERLKENWPEVEFRTKTITNRSEDPAAGLQDALRKREID
IALHALRDLPPAQADGLHLTAVTRRVDPREAFVGRSAKRLEDLPDGAVVGAPSLRRKAQL
LAYRPDLVVRETKGDVDDQLEALGTGEYDAIIMPAGSLLRLDLRNRIDQFVDPEILLPAP
GQGALGLEVRLGDDYAEELAYSLNHRPSSDRVCAERAFVAALGVGLEAPVAALAFVEDDG
TLRLEGGVFSPDGREMIRGEIEGDASEAVELGSELAQDLLAEGGKEILEQAKVR
>E8TUD7|hydroxymethylbilane synthase|EC 2.5.1.61|Alicycliphilus denitrificans (strain JCM 14587 / BC)|TrEMBL
MTTSSALPPIVIATRESQLALWQAEHVQALLAARGHSVSLLGMTTRGDQILDRTLSKVGG
KGLFVKELEVALEEGRADIAVHSLKDVPMELPDGFALACVMEREDPRDAFVSPHHASLDE
LPQGAVVGTSSLRRQVLLQALRPDLKIEPLRGNVQTRLRKLDEGQYAAIVLAAAGLKRLG
LHERIRSVFEPGQMLPAAGQGALGIEIRSQRQDLRDALAPLAHERTWLTVTAERAVSRAM
GGSCSMPLAAHGVWSGDTLRLQAAWGDVEGRLPLVRAEGSSRVATLDEADALGLAVAGRL
RAAGAVAAC
>A0Y9F0|hydroxymethylbilane synthase|EC 2.5.1.61|marine gamma proteobacterium HTCC2143|TrEMBL
MPSNLVRIATRESPLALWQAEFIKAGLQAAHPGLDVELLGMTTRGDKMLDAPLAKIGGKG
LFVKELETAMLEGRADIAVHSMKDVPMEFPEGLELSIICEREDPRDAFVSNHFKTVNELP
LGSRVGTSSLRRQCQLRALRPDLNIIDLRGNVNTRLRKLDEGQYDAIILASAGLIRLGME
QRIADPIAVDSSLPAGGQGAVGVEARSDDHRIQALLAPLNHRSTALRVSAERAMNLRLQG
GCQVPIACFAELDIEGSGQLRLRGLVGSPDGKEILRCERQAKPEMAEALGIEVADNLLAQ
GAERILSAVYGQS
>H5VCN2|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter bizzozeronii CCUG 35545|TrEMBL
MKTLIIGSRGSALALWQASYVQGLLEQIGLKSTIRVVKTKGDKILDVPLAKIGGKGLFTK
ELETLLLNQEIDLAVHSLKDVPVEGLEPLGLAAITPRADPRDCFLSVRYACLADLPQGAR
VGTTSLRRSMQLKRMRADLDTLSLRGNIQTRLERLKCGDFDAIVLACAGVQRLGLELPHQ
QPFSTEEMIPSMAQGALGVQMRRDHPYFDQIAQLNDPTSAFVCGLERCFVRQLGGGCQVP
LGVHASLTQDRLQIQAIVGLSDGSCVLQERIQGQPSQADHLINTLVQNFLDQGAREILDQ
ATLLN
>A8KTG4|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei Pasteur 52237|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>E7T4S7|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella boydii ATCC 9905|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGRRPGMSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGRQLPQLADQL
AALGESDLLFALSQHAVAFAQSQLHQQDRKWPQLPTYFAIGRTTALALHTVSGQKILYPQ
DREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTVRGAEVTFCECYQRCAIHYDG
AEEAMRWQSREVTMVVVTSGEMLQQLWSLIPQWYREHWLLHCRLLVVSERLAKLARELGW
QDIKVADNADNDALLRALQ
>G0H000|hydroxymethylbilane synthase|EC 2.5.1.61|Methanococcus maripaludis|TrEMBL
MKLRIGTRGSTLAMVQTEYIAGLLNDLDIETEIIIVKTTGDKDQNKKLADLGIGVFTKEL
DNKMLENEIDIAVHSLKDVPTLWSEELQITATPKRESPDDIIIWRKDCDFDIEHDELNVG
TSSIRRTSFLQFTNPNLTPKLLRGNVATRINKLRNGEYDTIVMAKAGLVRQGIDLSEFNY
KKLDILPAPAQGVIGVASRKADTKINQILEKICDKKTYIEATAERWALKEYGGGCQAPFG
AFAVYDTEEGILNLRCELVDEQGTIKRVKSNEGFVICTTDDVELSKELGARVGASFKEFE
TFTY
>E7RIH5|hydroxymethylbilane synthase|EC 2.5.1.61|Planococcus donghaensis MPA1U2|TrEMBL
MRKIIVGSRRSKLALTQTNQFIDKLKAAGAPFEFEIKEIVTKGDRIVDVMLSKVGGKGLF
VKEIEQALFDREIDFAVHSMKDMPSVLPEGLAIGCIPEREDPRDAYIANDHVKLLDLPVG
AVVGTSSLRRSSQLLLLRPDLDIQWIRGNIDTRLAKLKSGDFDAIILAAAGLKRMGWKDD
LVTEFLEVDECLPAIGQGSLGIECREEDTELLSELAKLNHEDTALAVNAERKFLKDMDGS
CQVPIAGYATVKDGEVTFTGLISSPEADQVFKEMAISHDPIEAGRIVAEKISAQGGYDLI
QRVKAESNV
>A3TVL5|hydroxymethylbilane synthase|EC 2.5.1.61|Oceanicola batsensis HTCC2597|TrEMBL
MTRDFPSPARPLKIGTRGSPLALAQAHEARDRLAHAFDLPPEAFEVCVIQTTGDRVQDRP
LKEIGGKGLFTREIEHALLTGGIDIAVHSMKDMPVLQPEGLLLDCYLPREDPRDAFVSNL
YERLDQIPAGARVGTSSLRRRAQVLVRRPDLEVVEFRGNVQTRLRKLADGVASATFLAMA
GLNRLDRASIARSALATDEMLPAVAQGAIGIERREDDHATAALLEAIHDPETARQLAAER
AFLAALDGSCETPIAGLADLEGGTLRLRGEILRPDGSEALKDDRSAPVEDGAKLGREMGA
ALLAQAGDGFFDFRG
>H5R191|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC15D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHKTALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A6F8Y9|hydroxymethylbilane synthase|EC 2.5.1.61|Moritella sp. PE36|TrEMBL
MATETLRIATRKSPLAMWQAEYVKARLEAIHQNLTVELIPMVTKGDIILDTPLAKVGGKG
LFVKELEVAILENRADIAVHSMKDVPVEFPEGLDLEVICEREDPRDAFVSNTYRQIEELP
PGAIVGTCSLRRQCQLSEARPDLKIMDLRGNVNTRLNKLDNKDYDAIILAAAGLKRLDME
YRIASYIEPEQSLPAVGQGAVGIECRIDDERVKALLAPLNHALTSDRVLAERAMNLALEG
GCQVPIGSYAIIDGDELWLRGLVGKPDGTEVIRAEIRGDRKNARQLGLELADKLLAQGAK
EILAAVYDSSDT
>Q18ES3|hydroxymethylbilane synthase|EC 2.5.1.61|Haloquadratum walsbyi (strain DSM 16790)|TrEMBL
MTTRSRTRGTLTLATRGSDLALKQATSVQEALTDERYEVDLIEVETRGDQIQDELIHQLG
KTGAFVRALDKKVLDPTAEADAAVHSMKDMPTDSPDDLVVAGIPQRAPPGDLLITTDGQR
LSDLPSGATIGTSSLRRQAQLLDQRTDITVEPLRGNIDTRIEKLLAPSLQTEHEQRIEAE
QGEITNTENTGSDDEDIDRDETDKELPEFEQSIEAWFNELSEIERRALERSVETEYDAIV
LAEAGLQRSGLIHHIEYVQLDTTTFVPAPGQGAIAITTQGEANATAQIREAIDHPRTRVE
TTVERTVLAELGGGCIAPIGVHATLQGEYVHVAAQVFASDGTETVDGSRNLPVDAHADAA
AQFANKLADRGADELIAAARVAADESSNTESTGE
>G7ZP48|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus MSHR1132|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAIEPNLEIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPLDAYISKTHTPLSQLPDG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLHTENYDAIILAAAGLRRMGWSDD
TVTTYLDRDTLLPAIGQGALGIECRSDDVELLELLNKVHNEEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEFTSTGTDPVELGKLVSNKLKEQGAYDI
IKRLNEQQ
>B5N496|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. CVM23701|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>D2QCY9|hydroxymethylbilane synthase|EC 2.5.1.61|Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896)|TrEMBL
MHIRIGTRSSRLAVWQAEHIQALLEKGGLTSELVLIETKGDLVLDRSLAKIGSKGVFTQE
LEDQLRSGTIDIAVHSAKDLPSNLPADLHIIAFTEREPANDVLVSRNKSLSLQGGESFRI
GTSSTRRVAMLKHYCPQLATVDMRGNLQTRIRKLDEGHCDALLLAYAGVHRMGYDDLIVE
RLPLDEFTPAVGQGSIAIEVATDALKSDIAEAITRLINHEPTAACLRAERAFLARLEGGC
SIPSFALAQWTDDTTVSLTGGLVSLDGSQLLRETFSGSAQESHLLGHSLAEAILARGGDT
LLLDIRAQL
>D0LUE1|hydroxymethylbilane synthase|EC 2.5.1.61|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MSERTIHISTRGSQLALWQAHHVRDEIRRVRPAWQVELVIIKTQGDKILDVPLSKIGGKA
LFVKEIEQALLDGRADVAVHSMKDVPAELAPGLFMAATSRREDPYDALCTRDGRGLDELA
EGATLGTSSLRRQCQILARRPDLRIEMLRGNVPTRLGKLDDGSFDAVILAAAGLKRLGHG
ERISQRLDGGVCVPAVGQGVLGIETRQGDAPADRELVEALREALHDPAEERRVVAERAMM
AALGGSCQTPLAAHASYRGDSDPVAGTLVIEGLCGRPDGSEILRAQVEGRAEDAQALGSS
LAEELRGQGAQAIIDACTSA
>D0GWF2|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio mimicus MB451|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLKVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEVAMLEGRADLAVHSMKDVPVDFPKGLGLVTICEREDPRDAFVSNTYAKIDDLP
SGAVVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLGLE
SRIRNFIEPEQSLPAVGQGAVGIECRLDDQRVRELLAPLNHTDTADRVRCERAMNLTLQG
GCQVPIGSYALLDGDEIWLRALVGEPDGSQIVRGEIRGPRSEAEQLGITLAEQLLGQGAK
EILERLYCEHE
>D5TA15|hydroxymethylbilane synthase|EC 2.5.1.61|Legionella pneumophila serogroup 1 (strain 2300/99 Alcoy)|TrEMBL
MLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKGLFVKELEEALLDKRADLAVHSTKDM
PAQLPDGLLLAAICKRDNPFDALISPQFKSLDALPKNAIIGTSSLRRQSQLLAYNPNLQI
KTLRGNIHTRLSKLESGEYQAIILAAAGLERMGLAHHITQLIPDDIMLPTCAQGALCIEC
RTDDLEIQELIHGLNDPISALCVHTERRVNAKLGGNCHIPFAVYCTITEEKRLLLRAKVL
NMDGSQMIDDEQQGKIAEAEVIADRCTESLMTKGAMSLLSTIPS
>E4TRP6|hydroxymethylbilane synthase|EC 2.5.1.61|Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B-1430 / H-43)|TrEMBL
MNIRIGTRGSKLALWQAEYVKTRIEKAGHTAEIKIIQTKGDKILDVAISKIGSKGVFTEE
IEAQLEDGNIDIAVHSAKDMQSELPQGFDLIAFTEREKVNDVLVSHKDSIDINDKDNPIV
IGTSSTRRIATLKHFYPHIKTVDIRGNLQTRIRKMEEGLCDAILLAYAGVHRMEYDDKIK
LELSTQEFIPAVGQGSVAIEVHESIEDDKKQMLRFALNHRNTEYCLRAERAYLRHLQGGC
SIPVFGLATLNSNSIEMEAGIISLDGQERISMKLTDETSRAEELGTLIARQILKKGGDKV
LKEIREQLSED
>D2P2I6|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 1/2a (strain 08-5578)|TrEMBL
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEAIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNQVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPEVCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEFVQFKGLVGNADGSIILESEQVGANPSEIGNKVAEDLLSEGAD
TIIKELRNV
>E8M087|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio brasiliensis LMG 20546|TrEMBL
MTQTTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNSIDEL
PQGAVVGTCSLRRQCQIKEARPDLIIKELRGNVGTRLGKLDAGDYDAIILAAAGLKRLEL
EERIKSFIEPEQSLPAVGQGAVGIECRLDDDRLIKLLEPLNHKETADRVLCERAMNLTLE
GGCQVPIGSYSLIDGDNIWLRALVGEPDGSKIVRGEIRGSRTDAEALGVELANQLLADGA
KEILTKLYAEHE
>G7FJC5|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas sp. BSi20439|TrEMBL
MTEKTKLVRIATRKSALALWQAEFVKAQLEHFHDDVRVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLDGRADIAVHSMKDVPVEFPDDLELHVICEREDPRDAFVSNNFANIDA
LPQGAIVGTSSLRRQCQIRALRPDLEIRDLRGNVNTRLAKLDSGQYDAIILAAAGLIRLE
MGERIRDFIEPEVSLPANGQGAVGIECRIDDTVTKALLAPLEHSETRIRVNAERAMNRHL
EGGCQVPIGAYALVDGEQVHLRGLVGAIDGSEILRDEISGHVDDAEKLGIELAKKLLAQG
ADKILADVYRDA
>B7H1L6|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii (strain AB307-0294)|TrEMBL
MLEFMKTLKIATRQSPLALWQAEHIRARLQERHPDLTVELVKFVTQGDKILDTPLAKIGG
KGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQFEKFAD
LPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAGLKRLG
LAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLALIQPLLHPETDVCVRAERAFNAYL
EGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARNLLDQG
AGDLLKALY
>A6VFG4|hydroxymethylbilane synthase|EC 2.5.1.61|Methanococcus maripaludis (strain C7 / ATCC BAA-1331)|TrEMBL
MKLRIGTRGSTLAMVQTEYIAGLLNDLGVETEIVIVKTTGDKDQTKKLVDLGLGVFTKEL
DSKMLENEIDIAVHSLKDVPTLWSDELQITATPKRESPDDIIIWRKDSDFDIEHDELDVG
TSSIRRTSFLQFTHPNLTPKLLRGNVATRIDKLRNREYDTIIMAKAGLIRQGIDLSEFNY
TKLDMLPAPAQGVIGVASRKADIKINEILEKICDKKTYIEATAERWALKEYGGGCQAPFG
AFAVYDTEDGILNLRCELVDEQGTIKRVKSNEGFVICTTDEVELAKELGARVGALFKEIE
TFTY
>I3R0S0|hydroxymethylbilane synthase|EC 2.5.1.61|Haloferax mediterranei ATCC 33500|TrEMBL
MENHHDFPRSTRHDPIREERTGGLFNAGAGQQHMTTRTLRLATRGSALARAQATSVQEAL
AGRKLDVELVEVETTGDLIQDELIHRLGKTGAFVHALDERVLDGEVDIAVHSMKDMPTEK
PHDLVVAGVPERAPAGDVLITAEGHDIDELPEGAVVGTSSLRRQAQLLNYRDDIEVEPLR
GNIDTRIEKLLATHLQREHEARVENDKERQGKRGKTDHEAEFDESADEWFDGLTELERQA
MERKVETEYDAIVLAEAGLKRSGLDKKINYERLPRTDFVPAPGQGAIAVTASDSEVIDLV
KDKLDHPRSRVETTVERTILAELGGGCIAPVGVHALLQGEHVHVDVHVLATDGSESIKTS
RDLPVGNHANAARDFAAALRDRGAGQLVEAAREEAEEE
>F2IEC7|hydroxymethylbilane synthase|EC 2.5.1.61|Fluviicola taffensis (strain DSM 16823 / RW262 / RW262)|TrEMBL
MRNIRIGSRGSDLALWQANHVKKQLEALGAEVGITIITTKGDQIQDLSFDKLEGKGFFTK
EIEQALLDNSIDLAVHSHKDLETNTPEGLIIAAVSERENPADVLLIHPNAFDKDEFWSLK
KGAVVGTSSARRKSQVIAFRSDIEIKDLRGNVPTRLQKLIDGGYDAILLAKAGLDRLQLD
LKGMHEVVLDPEEFIPAPAQGVLALQIRENDNELYNFMQAMNHEDIQSQIALERNLLNRL
QGGCQLPLGAYCPEEGRLIVSFAHEWEQGAQWYEFEGPHDLDMIDVVLEALLGEEEEEDD
EDIS
>C6WYV1|hydroxymethylbilane synthase|EC 2.5.1.61|Methylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540)|TrEMBL
MQNSKLHTPPKKLVIASRESALAMWQARHIQSRLQALYPETEVTILGMTTTGDQILDTPL
AKVGGKGLFVKELEIALADGRADLAVHSMKDVPMNLPEGFILAATGEREDPRDAFVSNDY
ATLEDLPANSIVGTSSLRRQSQLQARFPHLKIESLRGNLQTRLRKLDEGQYAAIILAAAG
LIRLELGNRIRQFIAPEHSIPAVGQGALGIEISADRPDLIATLAPLNHPDTQVCVEAERG
MSRSLAGSCTVPLGAYAVCEADSIRITGFVASVDGKQMLIETAVGSRANAEALGKTLASQ
LVAKGADKILAAL
>B0HZD8|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis biovar Antiqua str. E1979001|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>F7RF18|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri J1713|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>C6DT96|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis (strain KZN 1435 / MDR)|TrEMBL
MAHVIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTA
LREAMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLV
GTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTE
TLEPVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAP
VGAIAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFE
LGARELMWGVRH
>E6NCI2|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain F16)|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSMESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSMKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCHLEREFVKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKAQLF
>I6CYE7|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella boydii 965-58|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F6DHE8|hydroxymethylbilane synthase|EC 2.5.1.61|Thermus thermophilus (strain SG0.5JP17-16)|TrEMBL
MRVVVVGTRGSALALAQTRFVVERLKETWPETEFKIRTIKTRGDQGASPREEAIFVKEIQ
EALLSREIDIAVHSLKDLPTESPRGLKIASVPRRQDPRDVFLGKAAKRLKDLPPGAVVGT
SSVRRKAQILALRPDLVVRDLRGNVDTRLAALGSGEYDGIVLAAAGLIRLDLRNRIDEFL
DPAEILPAPGQGALALEVREGDDLAEELCYALHHPPSYHRVRAERAFLRGLGAGCLAPVG
ALAHVEEDGTLRLEGVLLTPDGKSFIRAEIEGDVSEAEELGLDLARDVLEQGGREILAQI
R
>A3M1E3|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755)|TrEMBL
MLEFMKTLKIATRQSPLALWQAEHIRARLQELHPDLTVELVKFVTQGDKILDTPLAKIGG
KGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQFEKFAD
LPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAGLKRLG
LAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLALIQPLLHPETDVCVRAERAFNAYL
EGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARNLLDQG
AGDLLKALY
>E6X320|hydroxymethylbilane synthase|EC 2.5.1.61|Nitratifractor salsuginis (strain DSM 16511 / JCM 12458 / E9I37-1)|TrEMBL
MDKLTIVTRASQLALWQAYHIKDRIEKARPELEVELMEITSRGDKILDRPLALVGGKGHF
TKELEDEMLAGRAQMAVHSLKDVPTFIPEGLELAAITERQDQSDVFLSHRFSSLEALPEG
AVVGTTSLRRRMQLLQRRPDLIVKDLRGNVNTRLRKLAEGQYDAIILAYIGLARLDLLKE
IPHVQKLEWMIPPMGQAALGIEILSGDEELRHLAMELDDPETHLCTEIEREFVAAVGAGC
SAPVAVNARIIDGELDLRAMLGYPDASEVLYEELVLPMEEATGAGKRLAEKMIADGALEL
LAEAEKRAFKEERPERL
>I2I1A1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O32:H37 str. P4|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F5PXI8|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri K-671|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLCALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGEAPA
>C7NCC4|hydroxymethylbilane synthase|EC 2.5.1.61|Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249)|TrEMBL
MKSNKIIIGTRGSILALAQAEKVKEMLIKKYDELRENENFCEIEGFDKKNPLEIELKVIV
TKGDKDLRDFTKIKGTTQKDLFVKEIEKEMLENKIDLAVHSLKDMPQNTPEGLLNACFPM
REDNRDVLVSKNGKKLKELDENSVIGTGSIRREKELLNLRNDVKIKAIRGNIHTRLKKLD
DGEYDAIVLAAAGLKRVGLENRITEYFDKDSFMPAPGQGILCIQCRENDNKIRHLLKIIN
DDEVTIMCKAEREFSKIFDGGCHTPIGCSSVIEGNTLKLKGMFNDNGIRIFKEVEGNREN
PKETAQKLAEEIKKEEMKNEKR
>F2ER09|hydroxymethylbilane synthase|EC 2.5.1.61|Pantoea ananatis (strain AJ13355)|TrEMBL
MVNGMLNKIFRIATRQSPLALWQAQYVQQRLISAHPGLRVELVPMVTKGDIILDTPLAKV
GGKGLFVKELEQAMLENRADLAVHSMKDVPVAFPEGLGLVTICQRDDPRDAFVSNHYASI
DELPQGAVIGTSSLRRQCQISARRPDLVIRSLRGNVGTRLSKLDAGEYDAIILAAAGLNR
LGLADRIRQPLPADISLPAVGQGAVGIECRLDDSTLIALLQALNHDDTAVCVRAERAMNT
RLEGGCQVPIGSFAVLEGDELWLRGLVGAPDGSVMVSGERRGPRDQAEQMGISLADELLN
GGAREILRDVYQGQPPV
>Q2GJX6|hydroxymethylbilane synthase|EC 2.5.1.61|Anaplasma phagocytophilum (strain HZ)|TrEMBL
MGIVMVIRIGTRGSLLAMQQARIVKTAIETNYAELSTRIITIKTSGDMNTHVPLYDIGGK
GLFIKEIEEALLDNIIDVAVHSAKDVPGIYSEDLDIPCILPRASALDAFLSSKYDSIASL
PLNAKIGTSSVRRKVQLLTMRPDLEIIPMRGNVETRISKMQMGECDGIVLAEAGLYRVSK
DNLISEVLQPEVMLGAVGQGAICVQCRRYDRRILEILKKLNCHKSYTTVSAERSFMRAVD
GSCNTPLAAMAKYIDMDILTMKCMLADDARNMVFTERVFAEQNAESAGYEMGTLLKNELH
LHRL
>E0R9Z0|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus polymyxa (strain E681)|TrEMBL
MRTIVVGSRQSALALTQTGHVIEDLNALCAEQGMDLQFVVKKILTKGDRILDVTLSKVGG
KGLFVKEIEQAMLAGEIDMAVHSMKDMPSELPEGLVNGAVPHREDPRDCLITLGAKSLED
LPQGAKVGTSSLRRASQIKSMRPDLQLEPVRGNIDSRLKKLETEGFDAIILAAAGLHRMG
WKERITSYIPEADCLPAVGQGALGIECRASDEELLALLRLYNDRDTSATVAAERTFLGVL
NGGCQVPIGAHAVWAGQEISLTGMVGSPDGEVILKETLQGNDPQKLGEAVAASLIAKGAE
QILAQVRG
>G6ZZ83|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-22A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>A5FLE5|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101)|TrEMBL
MAEKTIRIGTRDSELALWQAHNVEKKLNDLGYKTSIVAVKSQGDIILDKPLYELGITGIF
TKTLDIAMINGDIDIAVHSMKDVPTALPKGIVQGAVLPRANVLDILVHKGNPDFTNPSTI
ATGSLRRQAQWFNKYPNHTVVDLRGNVNTRMQKLQDNNWDGAVFAAAGLERINLKPENYI
NLDWMIPAPAQGAMLVVGMENDNYTLDALSQLNDIETEICTHIERQFLRTLEGGCTAPIG
ALVTYNEDEDTLHFQGVLLSIDGKQKLEINKTVDISEWKKLGFNSAQEILNNGGTELMQK
IKESLKK
>C4FK63|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurihydrogenibium yellowstonense SS-5|TrEMBL
MKIRIGTRKSQLALWQANYIADRLREIHGVEVELVKITTQGDKILDVPLAKIGGKGLFVK
EIEDALLKNEIDIAVHSLKDVPTVLPEGLELIAITEREDPRDAFLSIKHEHIYQLPENAV
IGTSSLRRKSQIMKIRKDLQIKDLRGNVDTRIRKLEEGQYDAIILAYAGLKRLGLDGKVK
YIFSPDEMIPAVCQGFLAIEGRSDDERIKNLIKPLNHYESYLRATAERSFLKTLEGGCQV
PLGAYCEIKENSFIITGFIADLEGREYYQEKITEQIKENTQEQAIILGKTLAEKLLNDGG
KQILTKIYGK
>C4FK63|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurihydrogenibium yellowstonense SS-5|TrEMBL
MKIRIGTRKSQLALWQANYIADRLREIHGVEVELVKITTQGDKILDVPLAKIGGKGLFVK
EIEDALLKNEIDIAVHSLKDVPTVLPEGLELIAITEREDPRDAFLSIKHEHIYQLPENAV
IGTSSLRRKSQIMKIRKDLQIKDLRGNVDTRIRKLEEGQYDAIILAYAGLKRLGLDGKVK
YIFSPDEMIPAVCQGFLAIEGRSDDERIKNLIKPLNHYESYLRATAERSFLKTLEGGCQV
PLGAYCEIKENSFIITGFIADLEGREYYQEKITEQIKENTQEQAIILGKTLAEKLLNDGG
KQILTKIYGK
>F5RMU0|hydroxymethylbilane synthase|EC 2.5.1.61|Centipeda periodontii DSM 2778|TrEMBL
MTTKGDRILDAPLAKIGGKGLFTKELEQAMLAGEIDLAVHSLKDMPTEVPEGLVIGAITQ
RLDAGDAFVSVHYRSMEDLPQGARVGTSSLRRRAQLLAVRPDLTILDLRGNVNTRLAKLD
AGEFDAIVLAAAGLKRLGLGERIRTILPRAMILPAVGQGALAIECRADDGRIQEMIDFLR
DTEMTAAATAERAFLRRVEGGCQIPVGVYAEVGEGNVLHVEAMIASIDGMRVCRSHSMGT
PAEAEKIGIALAEELLDVGGREILKEIGIAV
>H0LAI7|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 80959-06|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I5M5R7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA40|TrEMBL
MMASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVP
VEFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIR
SLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECR
LDDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAP
DGSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>C0N2Y6|hydroxymethylbilane synthase|EC 2.5.1.61|Methylophaga thiooxydans DMS010|TrEMBL
MSKRTVRIATRNSPLAVWQAEFVKDSLLALHPDLTVELVKMKTQGDIILDTPLAKVGGKG
LFVKELEQGMLDGRADIAVHSMKDVPVEFPEGLHLPVICKREDPHDAFVSNHYQTIDDLP
HGARLGTSSLRRECQARTHRPDLEVLPLRGNVNTRLRKLDEGQFDAIILAMAGLKRLGFD
DRIRSALTPEQSLPAIGQGALGIETRIDDDEMNALIAPLHCPQTAIVLTAERALNRRLSG
GCQVPIAGYAMLEGDEVWLRGLVGRPDGTNTLYADVRGAAKDADKLGVQIAETLLTKGAD
KILADVYGD
>F0ACN2|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis M13399|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESESLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>A3PM70|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)|TrEMBL
MDSANQIGMTHSMPTPAEPLKIGTRGSPLALAQAYETRSRLSAAFSLPEEAFEIVVIKTT
GDKVLDRPLKEIGGKGLFTREIEEALLSGGIDIAVHSMKDMPTLQPEGLILDTYLPREDT
RDAFITFAEGGLADLPQGATVGSSSLRRRAQLLNKRPDLQVVEFRGNLQTRLKKLNDGVA
RGTFLAMAGLNRLKMNEVPRVPIEPEEMLSAVAQGAIGIERRTDDPRAQEMLAAIHDVPT
GHRLAAERSFLLKLDGSCETPIAGLAILEGDQLWLRGEILRPDGSESISGEIRGAIADAA
ALGVELASELLGRAPADFFSWR
>Q022E4|hydroxymethylbilane synthase|EC 2.5.1.61|Solibacter usitatus (strain Ellin6076)|TrEMBL
MLVIASRGSQLALWQAHWVEAQLQAAGHECRIEIIKTTGDKITDVPLAKVGTKGLFTKEI
EEALLDGRAQLAVHSLKDLPTELPEGLVLGAVPKREDPRDAVIGKTLAELPLGAKVGTSS
LRRSAQLKRLRPDLVVESIRGNLDTRLRKLDEGQYDAILLAAAGMKRLGWGARIAEILPP
DLMCPAVGQGALAIETRAGFVLPAVLNHADTHTAVLAERGLLGALGGGCQVPIGAHATVA
GGRVRLLGLVAAPDGSEIVRAEAEGASGEAAEIGKRLGAELLARGARRILDGVYGVA
>C6AYV2|hydroxymethylbilane synthase|EC 2.5.1.61|Rhizobium leguminosarum bv. trifolii (strain WSM1325)|TrEMBL
MQTKPFRIGTRGSPLALAQAHEARDRLMAAHHLPEDMFEIVVLTTKGDRITDRSLAEIGG
KGLFTEELEQKLAAGELDFAVHSAKDMATKLPEGLYLSAYLPREDIRDAVIGRTARKLID
LPHGATVGSSSLRRQALIRRMRPDINVITFRGLVETRLRKLEQGEVDATLLALAGLKRLG
KVDVLTDILDPDTFPPAPAQGAICIESRIGDARVDDLLAPVNDGPTFDTVSCERAFLAAL
DGSCRTPIGGYAVCEGDLIRFSGLIITPDGRSQHAVTTDGHRRDAAALGTRAGQDVRARA
GSAFFDDWH
>C6S5F9|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis (strain alpha14)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLQADAQASAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>A3WKE8|hydroxymethylbilane synthase|EC 2.5.1.61|Idiomarina baltica OS145|TrEMBL
MFKRNVTKPLIQLCIVFSSVCALAACGQKGPLQPAPMPEKNQQQPQPQQPSNADESVKL
>H0AH00|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21178|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E7NYT0|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. glycinea str. B076|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDELP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
NRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPAGSVLLHAEARAPQTSAQALGVQVAEALLAQGAA
DILKAVYGEANNE
>I4H2C9|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 9807|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSENQD
YQLDTLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDADPEVLEVLKVLEHAPSRDRCYAERA
FLRELEGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VRDAGAGEILAEIFAEVGR
>H4D4E8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG547|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H5PBL9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC14D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H8DL98|hydroxymethylbilane synthase|EC 2.5.1.61|Pantoea sp. Sc1|TrEMBL
MLDKIFRIATRQSPLALWQAHYVQQRLMSAHPGLRVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELAMLDGRADMAVHSMKDVPVDFPEGLGLVTICERDDPRDAFVSHHYDSLDALP
QGAIVGTSSLRRQCQISARRPDLVIRSLRGNVGTRLSKLDAGEYDAIILAVAGLKRLGLE
DRIRQALPAEVSLPAVGQGAVGIECRLDDTTLIGLLQALNHDDTEVCVRAERAMNTRLEG
GCQVPIGSFAVLEGDELWLRGMVGAPDGHVMVSGERRGPRSQAREMGISLADELLDGGAR
EILQDVYQGQPPA
>D5E721|hydroxymethylbilane synthase|EC 2.5.1.61|Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP)|TrEMBL
MIIGTRGSDLALAQAKTVEGLLDSRGFPTTRKIIKTSGDTFTDRPLHEVEGVGAFVRELD
DRMLSGEIDIAVHSMKDLPTERPAELSIAAVIERDSPHDLLLTNDGSTLDELPEGAIVGT
TSMRRRAQFLRYRPDLDVQDLRGNINTRLKKLESGMYDAIILAEAGLQRMGWDIECHRLD
GDNFCPSANQGTIAVVTLAGGEAELLCSQIDHTESRIATEVERLVIRDVEGGCIVPVGSF
AEFVDNGNKIHIRAEILSLDGKRDIRLDEIIPVDNYREHAEKLGKKLVAMGGKELVKEAV
SQLSPKNN
>B0VMB8|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii (strain SDF)|TrEMBL
MFDRPMLEFMKTLKIATRQSPLALWQAEHICARLQELHPDLTVELVKFVTQGDKILDTPL
AKIGGKGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQF
EKFADLPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAG
LKRLGLAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLALIQPLLHPETDICVRAERA
FNAYLEGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARN
LLDQGAGDLLKALY
>I4FFF7|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 9432|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSQNQD
YQLDNLPEGSVIGTSSLRRLAQLRHHYPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDADPEVLEVLKVLEHAPSRDRCYAERA
FLRELEGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEALGRDLAHK
LRDAGAGEILAEIFAEVGR
>F1ZPP9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli STEC_7v|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLNDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H7G2L1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus DR10|TrEMBL
MNMRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKG
LFVKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLP
EGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWS
DDIVTSYLDRDTLLPAIGQGALGIECRSDDDELLSLLSKVHNDEVAKCVTAERTFLAEMD
GSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAY
EIIKRLNEQH
>F2K6R6|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas brassicacearum (strain NFM421)|TrEMBL
MCPREIRIATRKSALALWQAEYVKARLEAAHPGLIVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTFSSLEALP
AGSVVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSADSDIHALLAPLHHEDTATRVFAERALNKHLNG
GCQVPIACYAVLEGEQVWLRGLVGDPNGGRLLSAEARAPRHDAEALGVRVAEDLLSQGAA
DILKAVYGEAGHT
>H5ANF9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC8E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B7CI32|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei 576|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>E8H995|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. G5101|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H3URM7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU065|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>E6RHT7|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas sp. (strain SM9913)|TrEMBL
MTEKTKLVRIATRKSALALWQAEFVKAQLEHFHDDVRVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLDGRADIAVHSMKDVPVEFPDDLELHVICEREDPRDAFVSNNFANIDA
LPQGAIVGTSSLRRQCQIRALRPDLEIRDLRGNVNTRLAKLDSGQYDAIILAAAGLIRLE
MGERIRDFIEPEVSLPANGQGAVGIECRINDEVTKALLAPLEHSETRIRVNAERAMNRHL
EGGCQVPIGAYALVDGEQVHLRGLVGAIDGSEILRDEISGHVDDAEKLGVELAKKLLAQG
ADKILADVYRDA
>I2BU32|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas fluorescens A506|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLKVSLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTFASLDELP
LGSIVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVEDSLPAGGQGAVGIECRTADSEIHALLKPLDHADTEVRVTAERALNKHLNG
GCQVPIACYAVLEGENLWLRGLVGDPDGGNLLTAEVRGPQRDAKALGIQVAEALLEKGAG
TILQKVYGEAGPQ
>F6AGQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas fulva (strain 12-X)|TrEMBL
MTREIRIATRKSALALWQAEHVKARLEAAHPGLKVSLVPMVSKGDKLLDAPLAKIGGKGL
FVKELETALLEDQADIAVHSMKDVPMDFPEGLGLFCICDREDPRDAFVSNTYDSLDALPA
GSVVGTSSLRRQAQLLARRPDLKIHFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFED
RIRASITVEHSLPAGGQGAVGIECRVGDAELQQLLSPLNHTETALRVTAERAMNKRLNGG
CQVPIACYAILEGEQLWLRGLVGEPDGSRLLRAEQRGSAEDAERLGIEVAEALLAQGAGD
ILKAVYGEASAE
>F3EC99|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. lachrymans str. M301315|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDELP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDASEYDAIILAAAGLIRLGFE
NRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGSVLLHAEARAPQTSAQALGVQVAEALLAQGAA
DILKAVYGEANNE
>A9WIS3|hydroxymethylbilane synthase|EC 2.5.1.61|Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)|TrEMBL
MARLLLGTRGSALARVQSVWVADALRTAFPSLEVELRIISTTGDRVLDVALSAVGDKGLF
VKELEHALLASEVDLCVHSAKDMPTATPDGLVLAAFPVRVDPRDVLVVRQAGLGTDLATL
PAGARVGTSSLRRTSQVRHHRPDLQLTDVRGNVDTRLRKLASGQYDALILAAAGLRRLGL
WDGTPGAQIGEAVVYPLEPSVMLPAVAQGILAIETRADDEATRTLVESLDDPAARAAALA
ERALLRRLEGGCQIPVAAHAVMTDTGMHLRGMVGTLDGSTLVFAEQTGDPAQAEALGVAV
AEELLARGGDAILTAIRHQLEARR
>Q89SK2|hydroxymethylbilane synthase|EC 2.5.1.61|Bradyrhizobium japonicum (strain USDA 110)|TrEMBL
MALAQTEEIARRLTAAVPGLDVEIVKFDTTGDLDQTSKLLPHGGKGGAFVAQIRAAVLSG
ELQAAMHSLKDMPGNEDTPGLVIGATLSRDPPSDALVLRDGVTLEALRQSRGKGFKIGTN
AVRRAAYARRLFPDVEVIHFRGAADTRVRKLDNGEKQRLPDGGAVGPADALIMARSGLDR
VGLASRIAYEFTPAEMLPAAGQGIVAVECAAQDWQTRKILSSIDDPAAHACADAEREVLW
VLNGHCNSPVAGFSTIAGDQMSLTASVLDLSGNTIIEASRTGSANRPRELGRAVGLELLG
KGAAEIIERSRPR
>D7CNA5|hydroxymethylbilane synthase|EC 2.5.1.61|Syntrophothermus lipocalidus (strain DSM 12680 / TGB-C1)|TrEMBL
MKGTTLMAVKVRIGTRGSRLALWQANYVVKRLRDCFPGHEFEITVIKTKGDKITDVALSK
IGDKGLFTKEIEMALLREEIDIAVHSLKDLPTTLPEGIRLAAVLERENPLDVLLSFKGYS
LSGLPRGARIGTSSLRRTAQLKRLRPDIETVNLRGNVETRIRKMEDEGLDGIVLAYAGVK
RMGFLHLVTEILHPDQVIPAVGQGVIALEIKEDGKVAEELVKPLNHQPTWAEITAERAFL
KAIEGGCQVPCGCHASYQEGYLTVDGLVASLDGQVVYRDRVSGSEAFAQQLGEELARRIL
AMGGGSLLETVRCMGD
>E0M1L4|hydroxymethylbilane synthase|EC 2.5.1.61|Pantoea sp. aB|TrEMBL
MVNSMLDKIFRIATRQSPLALWQAHYVQQRLMSAHPGLRVELVPMVTKGDIILDTPLAKV
GGKGLFVKELELAMQDGRADMAVHSMKDVPVSFPEGLGLVTICERDDPRDAFVSHHYDSI
DALPQGAIVGTSSLRRQCQISARRPDLVIRSLRGNVGTRLGKLDAGEYDAIILAVAGLKR
LGLEDRIRQAMPAEVSLPAVGQGAVGIECRLDDSVLIDLLRALNHDDTEVCVRAERAMNT
RLEGGCQVPIGSFAVLEGNDLWLRGMVGAPDGRVMVSGERRGPRAQAEQMGISLADELLN
GGAREILKEVYQGQPPA
>E6SLS5|hydroxymethylbilane synthase|EC 2.5.1.61|Thermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a)|TrEMBL
MTAPVVRIGTRASALARIQAQWVARELQRHHPGLQVELVPVTTHGDRHRARPLYTLDTPG
AFVKELEEALRAGIIDLAVHSAKDVPTRLPEGLELAAFPQREDPGDALVLPRSQEGLGPN
GRDAGRGAGMTALELLPPGARVGTSSLRRQAWLRARRPDLKVEPARGNLDTRLRRLDEGA
WDALVLAAAGLRRLGVGHRITAAIPPRALLPAPGQGALAVEIRASDDATRRLVQVLDRPE
VALAVRAERAFLAELGGTCRIPLGAWARLEGPRLRLAGMVAAPDGDPWLEEEVEGPATDP
EAVGRELAERLRARGAESVLAAAGAAPGRGAAGRA
>D7FMY2|hydroxymethylbilane synthase|EC 2.5.1.61|Ectocarpus siliculosus|TrEMBL
MPVLKSTAAVATVVLAGSTQAFAFMGTPVVHGGAAHTSRAASSTSSGECGVRMAGDALLT
IGTRGSPLALAQAYETRKRLGEQFDELKEEGAVAIQVIKTSGDMILDKPLTEIGGKGLFT
KELDVQLLNKDVDICVHSMKDVPTWIVPGTILPCNLPREDTSDAFISNKADNIASLPDGS
VIGSASLRRQAQLLRANPTFKVVNFRGNVQTRLRKLDEEIVDATLLAFAGLKRLEMAQVA
TSVLDQDAMLPAVAQGAIGIQCRENDPTFEKYLAGLCHQETKTAVDCERAFLAALDGNCK
TPIAGQARMEGEKLVFRGLIASPDGKQFYDTTREGKPEDAVAMGHDAGMELKKRAGPEFF
AEFFAAGAQPATA
>F0LQY8|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio furnissii (strain DSM 14383 / NCTC 11218)|TrEMBL
MTSTTPIRIATRQSPLALWQAHFVKDALQAAHPGLEVELVTMVTRGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYASLDEL
PHGAIVGTCSLRRQCQLKEARPDLVIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EQRIRSLIEPEQSLPAVGQGAVGIECRLDDARLRALLAPLSDADTTDRVLCERAMNLTLE
GGCQVPIGSYALLDGDDLWLRALVGEPDGSHIVRGEIRGPRQDAERLGVELANQLLADGA
RDILTKLYAEHE
>F0BSM6|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas perforans 91-118|TrEMBL
MTTLRIATRKSPLALWQSEHVAAALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDAPFVLPAILERGDPADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEAR
ISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAAFARWEGQGLFLQGMVGSASDGRLIHADAHGSAEDTEALGRRVAQGLFDKGAAQL
LAEL
>B7UNC0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O127:H6 (strain E2348/69 / EPEC)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>H1M6U3|hydroxymethylbilane synthase|EC 2.5.1.61|Prevotella dentalis DSM 3688|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKQVRPDLDIEIKEIVTKGDRIVGKQLSKVGGKGLF
VKEIQNELFEKQIDMAIHSLKDVPSVIPEGLTLGCIPDREVPFDAYISKNHIPLRELPEG
SIIGTSSLRRGAQILSKYPHLEIKWIRGNIDTRIQKLETEDYDAIILAAAGLRRMGWSDD
IVTTYLDKDILLPAIGQGALGIECRSDDEELLDLLQEVHNKDVEKCVTAERTFLAEMDGS
CQVPIGGYATINSQQQIEFTGLIMTPDGTERYEHTAIGDSPTELGKEVSRVLKEQGAYEI
IRKLNEE
>E3CWT1|hydroxymethylbilane synthase|EC 2.5.1.61|Aminomonas paucivorans DSM 12260|TrEMBL
MILLTRGSPLARIQTRGWMDALESLGAETTLQAVSTHGDRDRTTPLPCFGGFGAFVKALE
EKLLAGEGDGAVHSLKDVPVAQPEGLVLAGVLPRGPVGDLLVTREGLSLETLPPGARVGS
SSLRRTAQGLRVRKDLRFLCCRGNVQTRLRKLEAGELDALILAEAGVRRLGLDLPGAVRL
PFLSTPGQGAVALEARAGSVLESLARQTNHLPTWLEVCGERQVLGAFGKGCSAPVAVQGR
YEGGVLTLEAEVLALDGSQSVGASLGGPAGTEEEARALGQTLWDSLAEAPLVRRLLEEVT
A
>C1AA38|hydroxymethylbilane synthase|EC 2.5.1.61|Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505)|TrEMBL
MMTVPVRIGTRSSELALRQARQVAAQLDARGVPSELVEYTTLGDRILDRPLSAIGEKGLF
TAELEADLLAGRIDCAVHSLKDLPTADPQGIIVVALLEREDPRDALVVRAGVDAHSLDTL
PEGARVGTSSLRRRAQLQALRSDLEVCELRGNVGTRLRKLDEGQVDAALLAAAGLHRLGL
ADRIVAYLDAPEWLSAPGQGAIAVQGRADDEALLSTLSSLDHAPTRVAVTAERALLAALE
GGCQVPIGAAVLEEPEYGTILHAVIVSLDGSSAVRGGYPVDHANPAASGIELARQLRAAG
GAQILSEIR
>F8ACV8|hydroxymethylbilane synthase|EC 2.5.1.61|Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812)|TrEMBL
MRKHIKVGTRGSKLALAQTNWVIGQIKERYPEIQVETVIIKTKGDKILDVPLAKVGGKGL
FVKEIEDALLREEIDLAVHSMKDVPTELPEGLEIAIIPERESPYDVVISQGGESIDDLPS
GATVGTSSLRRSAQLKAYRPDLKIENLRGNLDTRLRKLNEGLYHAIIVAQAGLIRLGLKE
ERAKPISPEIMLPAIGQGALAIEVRESDHDLKEGLSFLHHEETAICVAAERAFLATLEGG
CQVPLAAFARLSGDNLTVEGLIADPSGETILKEELKGPKEEAQALGRKLAEILLGRGGRK
ILDEVYGRA
>H7YH44|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 9879|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>H7SRL1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 1091|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>B0C8A9|hydroxymethylbilane synthase|EC 2.5.1.61|Acaryochloris marina (strain MBIC 11017)|TrEMBL
MIRIGSRKSQLALVQTHWVQGELQKHFPEYEFEVCTMSTQGDNILDVALAKIGDKGLFTK
ELEVSMLRKETDLAVHSLKDLPTNLPEGLCLGVVTERVDPADALVVHENFKAYQLDTLPE
GAVIGTSSLRRLAQLRYNYPHLEFKDIRGNLNTRLQKLDEGEYDGIILAVAGLQRLGFGD
RIHQVIPANISLHAVGQGALGIECREGDEEIMAFIKALEHEPSAHRCTAERSFLHELEGG
CQVPIGVNTSLKEGQLTLVGMVASLDGKRLIKDTVSGPIASATQLGIDLAQKVREQGAQE
ILEEIFAAARPSDL
>H7XLA1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 23223|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>H3ZET5|hydroxymethylbilane synthase|EC 2.5.1.61|Alishewanella jeotgali KCTC 22429|TrEMBL
MQRIRIATRKSALALWQAEFVKAELLKHHPELTVELVPMSTQGDKILDTPLAKIGGKGLF
VKELETAMLEDRADIAVHSMKDVPVEFPDGLMLSTICEREDPRDAFVSNQFRAIAELPPG
AVVGTSSLRRQCQLKALRPDLQVRDLRGNVNTRLAKLDNGEFAAIILAAAGLLRLGFAER
IAGYLPVEQSLPANGQGAVGIECRTSDQRVQALLAPLEHGITRNCVLAERAMNRRLQGGC
QVPIGAFATQHGEQITLRGLVGSLDGSEIIRDQVQGPASSAEALGQQLAERLLAAGAGKI
LTAVYQGS
>A8EYK9|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia canadensis (strain McKiel)|TrEMBL
MGMTVIMNKQELRIYFKDLLIKTQEKITSGLVRHSLISKISHLLKKLEIQTVGLYYPLKY
EINLLEITNLHPEIKFFLPKIIKNEIQYCPYHYKDSLALGNFKTFEPINNDLFIPELVII
PGLAFSSDGYRLGYGKGHFDQYLNNNPNILTAGVCLKEQLINNFPVESHDIKLKFVISV
>A0NYU8|hydroxymethylbilane synthase|EC 2.5.1.61|Labrenzia aggregata IAM 12614|TrEMBL
MRIGTRGSALALAQAHETRDRLMAAHGLAEDSFEIVVIKTSGDRIQDRPLSEVGGKGLFT
KEIEEALLDGRIDLAVHSSKDMPTVLPDGLALTAFLPREDVRDAFLSPKAKTLTDLPHGA
VVGSSSLRRQAMIKRLRPDIEVVMYRGNLQTRLRKLAEGAVDATLLAAAGLRRLGLEAEI
TSLLETDQFLPAVGQGAICIESRADDTATLEMLAAIHDEATQIRLDAERAFLAVLDGSCR
TPIGGLATLDGDTLHFRGIVLKPDGSEVHEATASGLKSDAVQIGRSVGEDLKSCMGPDFM
VGA
>E4RAX4|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas putida (strain BIRD-1)|TrEMBL
MSTREIRIATRKSALALWQAEYVKARLEQAHTGLQVTLVPMVSRGDKLLDAPLAKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTFDSLEALP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSTISVDDSLPAGGQGAVGIECRSADVEIHALLAPLHHVDTADRVMAERALNKRLNG
GCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRAAAEALGVQVAEDLLGQGAE
AILKEVYGEAGHP
>I4INN7|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 9701|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELELGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSQNQD
YQLDSLPAGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDGIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDGDAEVLQVLKVLEHAPSRDRCYAERA
FLRELQGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VREAGAGEILAEIFAEVGR
>B6BLL9|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacterales bacterium GD 1|TrEMBL
MNKLVIATRVSDLALWQAYHIKARVEASYPEITVELNKIVSNGDKVLDKPLALIGGKGHF
TKELEDEMLAGNADIAVHSLKDVPTYIPEGLELVAVTQRQDQSDVFLSHKHATLEDLPQG
AVVGTTSLRRRMQLLQQRPDLKVKDLRGNVNTRLRKLSEGQYDAIILAWIGLHRLDLLKD
VPFTQKLSLDMMIPPMGQAALGIEIVCGNAKVREIAESLKDLNTFICTQIERDFISKIGA
GCSAPVACNAVIDDNIITFRVMLGFPDGTNIMQEKVVINVEDSDNLGSELAKKMIDNGAL
ELLKDAEKIAFKDEMPQRL
>G9UI92|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. SARB30|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H8BTX7|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 140-16|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>H4TVP6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC5D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPHGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I5KTS6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA32|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I4GAD7|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 9443|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSQNQD
YQLDTLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LERLGLGDRVHQVIPAAISLHAVGQGALGIECRDADPEVLEVLKVLEHAPSRDRCYAERA
FLRELEGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VREAGAGEILAEIFAEVGR
>D5V6W1|hydroxymethylbilane synthase|EC 2.5.1.61|Arcobacter nitrofigilis (strain ATCC 33309 / DSM 7299 / LMG 7604 / NCTC 12251 / CI)|TrEMBL
MKKIVIATRKSKLALWQSEYIKAELLKHYPDMVIELKTFSTKADKILDVPLAKIGGKGLF
TKELEIALENKEADIAVHSLKDVPVEFEEGFVLAALTKRFDPRDAFLSEKYASITDLPNG
AIIGTTSLRRRMELKLLRPDIELKDLRGNINTRIAKLKAGEYDAIILAATGVQKLQIEDE
VKYFTPISIDEMIPSMGQATLGIETLDNPELVEILSVLHDKNAEIESTIERSFVHTLEGG
CQVPIGVKATILDENSVDVRAIVGMPDGSEYVQEDIKINIDDYKTAGQALAQTFIDQGAK
ELLERAEKVAFQ
>I6FT50|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EPECa12|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D8P0A1|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia solanacearum|TrEMBL
MSSNARPTSVESPLAAQAPTQLVIASRESRLAMWQAEYVRAALQKYYPACDVSILGMTTR
GDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMELPAGFALPTILEREDP
RDAFVSNHYADLAALPAGAVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLSKLDRGDY
AAIILAAAGLKRLGLSERIRAVIAPEASLPAAGQGALGIEIRADRPDVQAWLAPLHHAPT
ALAVTAERAVSRRLGGSCQVPLAAFAQWTDDGALRLRAFVASQDGRRKLAAEGETTPATL
AEAEALGARVAQQMLDGGAHDILAALGADAPPAT
>B3Z8B2|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus NVH0597-99|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>C5TKQ0|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria flavescens SK114|TrEMBL
MIDFMPFSIFQATIMNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGD
QILDRTLSKVGGKGLFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFD
AFVSNQYARLEEMPKGAIVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLDNGEYDA
IILAAAGLQRLELDERIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHA
CVTAERALARALGGSCQVPLAAYCTEENGLLTLRGLVGHPDGSVILQADAQAPAEYADAL
GRAVAKKLADDGAEELIAAVLQEQT
>A9B547|hydroxymethylbilane synthase|EC 2.5.1.61|Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785)|TrEMBL
MNILTIGTRKSQLALVQTHAMRDALLAAHPQLTIELEHITTKGDAILDRPLAAIGDKGLF
VSEIEDAMRNGKVDLAVHSAKDLPSILAPDMTIAAYPERADPRDVLVGAEGRRLADLVPG
AKVGTSSPRRAAQLRHLRPDLTIIDIRGNVDTRLRKLDEGQYDAIVLAAAGLQRLGLLKR
VTQFFEPAEMTPAVSQGILGIEARAGDQRVADLLKVLDHAESRATAEAEKAFLATIGGGC
QVAVGAFATYQIGQLHLIGMIGALDGRLVRGELTGSASTAQALGTSLAQQLLAQGGRELL
>I2X1C7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 4.0967|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>D0IRA7|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain 51)|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCHLERAFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEAFLQSGAKEIL
EKVQLF
>A4G3V2|hydroxymethylbilane synthase|EC 2.5.1.61|Herminiimonas arsenicoxydans|TrEMBL
MKFPPPKKLVIASRESRLAMWQAEHVREKLALLYPQCAIEILGMTTRGDQILDRTLSKVG
GKGLFVKELEVAIAERRADLAVHSLKDVPMSLPEGFALAAVLEREDPRDAFVSNDYASLD
DLPDGAIVGTSSLRRQALIAARYPKLVIRPLRGNLDTRLGKLDKGEYAAIILAAAGLKRL
GMPQRIRAVLDPEQSLPAPGQGAMGIEIHADRADLQEWLAPLNHEATAQAVTAERTVSRN
FGGSCQIPLAAFATIENGTMRLRAMIATPDGKRVARADLNGAAHAPEALGGQIAELLHQQ
EANAILESCKTEDAGNA
>E6M5H4|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus curtisii subsp. holmesii ATCC 35242|TrEMBL
MQTIGSTERPLVIGTRASALALTQTRAVASDLEQRGLHVQVQTFTTEGDINRASLASLGG
VGVFAAALRVALLEGHCDLVVHSLKDLPTVPVDGLVVAATPTREDPGDVLVARDSLSLAD
LPAGSRLGTGSPRRARQIAVARPDIELVDIRGNVPTRVGRVKGLAAVAEQAGLPSGKAAE
DLDGVVLARAGLRRLGMDDAITDSLEGTVIPAGGQGALALETRSELLDSDEGRNFAQILK
FVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGVVTWDKHTEAPSGRLELTARVIGNQGE
VLEVNGETTVLLGAEAAQRDFALAAAEQLGVDLAGELLEAGAATIADLKAAKSASTQTDA
NQTICNEKELWGE
>E6M5H4|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus curtisii subsp. holmesii ATCC 35242|TrEMBL
MQTIGSTERPLVIGTRASALALTQTRAVASDLEQRGLHVQVQTFTTEGDINRASLASLGG
VGVFAAALRVALLEGHCDLVVHSLKDLPTVPVDGLVVAATPTREDPGDVLVARDSLSLAD
LPAGSRLGTGSPRRARQIAVARPDIELVDIRGNVPTRVGRVKGLAAVAEQAGLPSGKAAE
DLDGVVLARAGLRRLGMDDAITDSLEGTVIPAGGQGALALETRSELLDSDEGRNFAQILK
FVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGVVTWDKHTEAPSGRLELTARVIGNQGE
VLEVNGETTVLLGAEAAQRDFALAAAEQLGVDLAGELLEAGAATIADLKAAKSASTQTDA
NQTICNEKELWGE
>H4C7W0|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1214|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>B3IAX5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli E22|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>C6XKH7|hydroxymethylbilane synthase|EC 2.5.1.61|Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418)|TrEMBL
MSNKNSTQTQAKPLTNSTQIVKIGARGSPLAVQQAEDFAARFKEIVGNTVEIEIHTFTTS
GDQLLDKRLQDAGGKGLFTRELDIAQLSGRIDIVVHSLKDVPTVLPDGLQMGCYLPREDP
RDALFGKVGNIKDLPHGATLGTASLRRSAQALALRPDLKIVMFRGNVQTRLRKLEEGQAD
ATLLAAAGLNRLGMTDKAAGFMPKEEMLPACGQGIVCTTLTNNAEDWIFKACLQIDVLES
RIAAIAERAFLKRLDGSCRTPIAGHLSFNETGVDMRGEVLADDGSKRWFSQMSLDTIPDE
NQAASLGFELGEKVAKLRDNKGQ
>E2JU19|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC4206|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>F2R906|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)|TrEMBL
MTERALRLGTRRSKLAMAQSGHVADAVRRLTGRPVELVEITTYGDTSREHLAQIGGTGVF
VAALRDALLADEVDFAVHSLKDLPTAQHPDLVLAAIPEREDPRDVLIARDGLTLDRLPEG
ARVGTGSPRRMAQLHAYARNHGLDITCVPIRGNVDTRVGYVRKGELDAVVLAAAGLNRIG
GTDELLGGLSAEPLPVDTVLPAPGQGALAVECLASNTELVAALAPLDDPLTRAAVTAERS
LLAALEAGCSAPVGALADLLADDPGHGQVVTEMRLRGVVGTTDGSTLVQLSTTGPVPTSH
DEAMALGRELADEMLAKGAAGLMGERAL
>B4RQ79|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria gonorrhoeae (strain NCCP11945)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDRILDRTLSKVGGKG
LFVKELEQSLQDGRADLAVHSIKDVPMDLPEGFALAAISERANPFDAFVSNRYARLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
ERIRMILSESDSLPAAGQGALGIEIATHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLILRGLVGHPDGSIVLQADAQAPAGYADALGRAVAKKLADDGAQ
ELIGAVLNTEN
>B8HND9|hydroxymethylbilane synthase|EC 2.5.1.61|Cyanothece sp. (strain PCC 7425 / ATCC 29141)|TrEMBL
MTVSVSGSSRTIRIGSRKSQLALVQTYWVQEQLQKHFPDRSFEVHTMSTQGDKILDVALA
KIGDKGLFTKELEQGMLSQETDFAVHSLKDLPTHLPDGLILGCITERENPADALVMNEKY
RDRPLETLPEGAVIGTSSLRRLAQLRHYFPHLTFKDVRGNVNTRLAKLDAGEYDALVLAV
AGLQRLGFSDRIHQILPPEISLHAVGQGALGIECRSDDPEVLSLIKALEHQPTAWRCLAE
RAFLRELEGGCQVPIGVNTQLEGDQLTLTGLVASLDGQRLIKDQITGAATTAEQMGTELA
QRLRQQGAEEILAAIFAEVRSS
>H4XBZ5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC7B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>G1C9L8|hydroxymethylbilane synthase|EC 2.5.1.61|Kinetoplastibacterium blastocrithidii|TrEMBL
MNKKITIATRASKLASAQAEHVRDLIKSLYPEIVVDFLVIVTQGDKILDRSLAKVGGKGL
FVKEIELALLNGDADMAVHSMKDVPADMTDSLDICSILKRHDSRDVFISNKYSSLDDLPF
DAVVGTSSLRREAQLKSVYSISIKCLRGNVDSRLKKLDDGDYSGIVLAAAGLERINLGHR
ISSYIDPSISLPAAGQGAIGIQIREDRSDIRSLVSSLSCIDTTFCVKAERIVMKVLGGSC
QVPLAANAYIKGGNIFLKAMVSSVDGKKVIRSQGSDNVDNWQILGECVANDLLDNGAYEI
LHSV
>E1SQB6|hydroxymethylbilane synthase|EC 2.5.1.61|Ferrimonas balearica (strain DSM 9799 / CCM 4581 / PAT)|TrEMBL
MARKEIRIATRKSPLALWQAEFVKAELEKAHPGLTVTLLKMSTKGDRILDTPLAKVGGKG
LFVKELEVAMLNGEADIAVHSMKDVPVEFPEGLGLAVICDREDPRDAFVSNTYKNLDDLP
HGAIVGSSSLRRQCQLRAMRPDLDVRDLRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
ERITAFIEPEQSLPANGQGAVGIECRLDDAELLALIGVLNHAPTHARVIAERAMNTHLEG
GCQVPIGAYSVIEGDTLWLRGLVGDPDGSKIIQDELRGPVADAQKLGIELAERLLAQGAG
EILKRVYGDA
>A9AHL0|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia multivorans (strain ATCC 17616 / 249)|TrEMBL
MGFLGKARVKRNCGNCENCGQATSYVRHIRASAPQAARGRGGRGRPARAGRSVRATIVRS
SIPSFDVPAMNSEILAAGPRPAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKI
LGMTTRGDQILDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMMLPDGFALAAI
MQREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARYPQLQVLPLRGNLDTRLSK
LDRGDYAAIILAAAGLKRLGLEARIRALLDVEDSPPAAGQGALGIEIAAHRTDVAAWLEP
LHDAQTALAVEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTIDGTRVLTAEECA
SVVTVADALALGRAVSDELEAQGALEIVRALLAGSQAGKGEA
>F3I164|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. actinidiae str. M302091|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFESLDALP
AGSIVGTSSLRRQAQLLARRPDLEIRFLRGNVNTRLAKLDGGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGRVLLHADARAPQTSAQALGVHVAEALLAQGAA
EILKAVYGEANNE
>B1UUY0|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus anthracis str. A0174|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>H8ALV6|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1997-7|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPRGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>H5AKV5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC8D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I4VND6|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodanobacter sp. 115|TrEMBL
VGTSSLRRQAQLRAARPDLQLLDLRGNVGTRLAKLDNGDYDAIVLACAGLERLGLHQRIR
SRLVAPAWLPAPGQAAIVVEARVQRAAVHERLAVLDDAETRLAVSAERAMNHALGGSCTV
PVGAWCTVAEHGLHLRGMVGEAATGRLLLAEATGTHDQPEALGLQVAEMLFAQGARALLE
G
>C6XGK7|hydroxymethylbilane synthase|EC 2.5.1.61|Liberibacter asiaticus (strain psy62)|TrEMBL
MEKKPFRIGTRCSPLALAHAFETRSSLMDVHKIPPHNIVIIPLSTKGDRITNRTLTEIGG
KGLFTEEIEKKLISGEIDCAVHSAKDMPTKLLKGLQISAYLPREDIRDVFISHTAQSLKD
LALHSVIGTSSLRRKALLLRWRSDISVIDFRGKIETRLNKLNNNKAHAILLAYAGIKRLK
KEKVIKEILNIEDFPPSPGQGAICIETHVNNPKAQELVKVINHEDTWDSVNCERAFLAEL
DGSCKSAIAGFAYCKGSTLYFYGIVLASDGKIFHEVSRNGNRCDAINIGRDAAQYIRFIS
NKNVFNF
>E7HEI6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EPECa14|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D5EI93|hydroxymethylbilane synthase|EC 2.5.1.61|Coraliomargarita akajimensis (strain DSM 45221 / IAM 15411 / JCM 23193 / KCTC 12865)|TrEMBL
MSILIATRKSPLALKQTEMVRAWLAEKLPNDHYEELQLTTQVDERLSWSLEKRGGIGLFT
KELEEALLANKATLAVHSAKDMPTTFQDDLCIAGYLPRARANDVIVKRSEIESPKRIATS
SPRRRAQLALLNNDAEWTTLRGNVGTRLRKIAEAQEADATLLAAAGLNRLDIQSYDGLDF
IELPIEQMVPAPGQAAIAIQCREKDLEKYQDLFCEDTKLAVTLEREFLHRLGGGCQTPVG
AHYNGTVFSIYHPQIGHTTYEFEIESILEIDGVLSAILGDLDLK
>D3EKN4|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus sp. (strain Y412MC10)|TrEMBL
MRTIVVGSRQSALALTQTGQVIDDLKRLAKEHGLEYDFAVKKIVTKGDRILDVTLSKVGG
KGLFVKEIEQAMIDGEIDMAVHSMKDMPSVLPEGLVSGAVPARKDPRDCLISKEGTTLDD
LPQGAKVGTSSLRRSSQLKAYRPDLQIDWIRGNIDSRIRKMEEGEFQAIILATAGLQRMG
WEDRITSYLPVEVSLPAVGQGALGIECRENDEELLHLLSLYNDEVTARTVAAERKFLSEL
NGGCQVPIGAYAVMKNVEAGDSRGEQNVIQLTGMVGSPDGEIVLKESAEGTDPEALGVEV
AAKLKAKGAEKILAQVRG
>H3WHL5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU128|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSIIPDGLTLGCIPDREIPFDAYIAKNHIPLEELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDVLLPAIGQGALGIECRSDDKELLDLLAKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIVHDNQIEFTGLIMSPDGKERYEHTTLGSDPVQLGIEVSQVLKKQGAYDI
IKKLNEAE
>E6T5R6|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella baltica (strain OS678)|TrEMBL
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAMLDDLADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELP
LGATVGTSSLRRQCQIRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
ERIASFISAEESLPANGQGAVGIECRINDERVKALLAPLEHLETRYRVLAERAMNTRLEG
GCQVPIGAFAEIDGDEMTLRGLVGNPDGSEIIEGVITGPKTDATQLGVALAEELLSKGAK
SILDAVYAKA
>D2TCR4|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia pyrifoliae (strain DSM 12163 / CIP 106111 / Ep16/96)|TrEMBL
MSDKILRIATRKSPLALWQAKYVQQRLIDCHPGLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEQAMLSGSADIAVHSMKDVPVAFPQGLGLVAICERDDPHDAFVSNRHASVDSLP
QGAIVGTSSLRRQCQLSARRPDLVIHSLRGNVGTRLGKLDAGEYDAIILAVAGLKRLGLS
DRIRQVMPAEESLPAVGQGAVGIECRLEDMHTIGLLAALNHDETACRVSAERAMNTRLEG
GCQVPIGSYALLEGDQLWLRGLVGSPDGSQMVRGERRGSRADAEKMGISLAEELLDNGAR
DILAAVYQGNPPA
>D6YHW7|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar G (strain G/11222)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>F0BJR9|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas vesicatoria ATCC 35937|TrEMBL
MTTLRIATRKSPLALWQSEHVAAALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDDPFVLPAILGRGDAADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLDAR
ISARLDAPDWLPAPAQGAVAVECRGDDARIHALLAVLDAPTTRVCVEAERAMNRALHGSC
HVPVAAFATWEGEGLYLQGMVGSASDGRLIHADAHGSAGDTEELGRRVAQGLFDKGAAQL
LAEL
>C4V2B2|hydroxymethylbilane synthase|EC 2.5.1.61|Selenomonas flueggei ATCC 43531|TrEMBL
MAEAIKKEHPSCCVELHELTTKGDRILDAPLAKIGGKGLFTKELEQAMLDDAVDLAVHSL
KDMPTEVPDGLVIGAITTRLDPGDAFVSAHYAAVEDLPVGARVGTSSLRRRAQLLAVRPD
LTICDLRGNVNTRLAKLDAGEFDAIVLAAAGLKRLGFERRIRTILPRSVMLPAVGQGALA
IECRAGDAAILSAIEFLRDAGMTTAAQAERAFLRRVEGGCQIPVGVYAEVDANGQISIDA
MIASVDGQRICRSDAHGAGEQAEALGTALAEELLDAGGREILKEIGITA
>E0MV78|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium accolens ATCC 49726|TrEMBL
PLRGNIDTRMSKVTDGELDAVVLAYAGLLRGGYEDRASDIFDPELFMPAPAQGALAIEAV
AGTEAAAALDAVVDEQATAAALAERAVLARLEAGCTAPVAATSRWNGDQLTVRGGVFALD
GSRQLTATASGTAAEAAELGARVSDELFAQGAADLLGQ
>E0MV78|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium accolens ATCC 49726|TrEMBL
PLRGNIDTRMSKVTDGELDAVVLAYAGLLRGGYEDRASDIFDPELFMPAPAQGALAIEAV
AGTEAAAALDAVVDEQATAAALAERAVLARLEAGCTAPVAATSRWNGDQLTVRGGVFALD
GSRQLTATASGTAAEAAELGARVSDELFAQGAADLLGQ
>H6LYW4|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. tularensis TI0902|TrEMBL
MKQITIASRESKLALWQTNFVKNRIQLELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>H5G422|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC10F|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D7DGI9|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar D (strain D-LC)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>H2I3Z2|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain VA01)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>H8CS08|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 9872|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVFLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIVSLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILKLLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>B5Q5J1|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Virchow str. SL491|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKY
HSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAG
LKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVIVRGERRGSPEQAEQMGISLAEE
LLENGARAILTEVYNGETPA
>F9MW05|hydroxymethylbilane synthase|EC 2.5.1.61|Peptoniphilus sp. oral taxon 375 str. F0436|TrEMBL
MLKDHYPDLTIEIIKISTKGDEILHKAIKDVGSKGVFVKEIEQALLDGKIDLAIHSMKDM
PGEVTPGLCFVDPPKGEDPRDVLITKDNKPLKKDGAYKIGTGSLRRALQLKRLYPNCQTV
PIRGNIETRMGKIQSENLDGVVLAYAGLIRAGYQDRVQHIFSEDDLIPAPCQGILALQVR
EDDREIQDLLKPLAHEKTTLRYQMQRAFQKTLNGGCQSPMGISSRIDDQRVYLRACFGNE
DGSVFCQKDLEGPLEDGVQLAQDLAQALKEEVYD
>Q1QEM1|hydroxymethylbilane synthase|EC 2.5.1.61|Psychrobacter cryohalolentis (strain K5)|TrEMBL
MSTMQQPALTTLNIATRQSPLALWQAEHIRNRLLALYPEMTINLLKIVTKGDKILDTPLA
KIGGKGLFVKELEQALYDKQADIAVHSLKDVPMDLPEGLTLGVYCKRASPTDAFVSNTYH
SIAELPQGAVVGTASLRRQCQIKAYRPDLQIKTLRGNVGTRLSKLDAGEYDAIILATSGL
KRIELDARIRSELDINICLPAVGQGALAIECREDDADVLKLLAPLNDDKARIRLIAERAL
NRHLQGGCQVPIAAYAVLQKADALAADNDSNDNDNGNNDAGDTLWLRGRVGQEDGSELLK
VDKRQTLTGSQAEQEAQANQLGIEVAEMLLQAGAGEILSAIYHPE
>H4R6Q0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC4D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I6BAC7|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri 2850-71|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>F2NNM8|hydroxymethylbilane synthase|EC 2.5.1.61|Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1)|TrEMBL
MRVIVVGTRGSALALTQTRWVVERLKEQWPEAEFKIKTIQTRGDRGAPPTDRDIFVKELE
EALLRGEIDIAVHSLKDLPTEQPEGLVIASIPKRVDPRDVFIGRNGIRRLEDLPEGAVVG
TSSVRRKAQLLAYRPDLVVRELRGNVDTRLSALGSGEFDGIILAAAGLLRLDLRNRIDAF
IDPKIMLPAPGQGALALEVREGDDIADELAYSIHHHPTDDRTTAERSFLHHLGAGCLAPV
GALAHVEEDGTLRLEGVVVAPDGSSMIHGEIEGDAEEAWELGAELARDILEQGGKRILEG
LRLEQ
>A7K599|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio sp. (strain Ex25)|TrEMBL
MTQSTPIRIATRKSPLALWQAYFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSNIDEL
PQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EERIRSFIEPEQSLPAVGQGAVGIECRLDDERLLKLLEPLNHQDTVDRVLCERAMNLTLE
GGCQVPIGSYALLDGDNIWLRALVGEPDGSEIVRGEIRGHRKDGEALGVQLANELLDNGA
REILTKLYADHE
>D3SNZ3|hydroxymethylbilane synthase|EC 2.5.1.61|Thermocrinis albus (strain DSM 14484 / JCM 11386 / HI 11/12)|TrEMBL
MHIRIGTRRSQLALWQANYVKRKLEDMGHTVELVPITTTGDKITDAPLAKIGGKGLFVKE
IEEALLRGDIDVAVHSLKDVPTKLPDGLTLGAITERELPYDVLISRDGQRLENLPTGAVV
GTSSLRRKVQIKRMRRDLVIKDLRGNVDTRIRKLDEGQYDAIVLAYAGIRRMGWENRIVQ
ILEDFIPAVGQGSMAVEIREDDEKIREVISLLDHRESRIRVEAERAFLEVMEGGCQVPMG
AIAWLDGSRLFMKGFLSDLEGENFVEAYVEGNVEKAQLLGRELAEKILSQGGRSILESIL
>G0EBI6|hydroxymethylbilane synthase|EC 2.5.1.61|Enterobacter aerogenes (strain ATCC 13048 / DSM 30053 / JCM 1235 / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006)|TrEMBL
MLDKVLRIATRQSPLALWQAHYVKERLESCHPGLSVELVPMVTRGDVLLDTPLAKVGGKG
LFVKELELAMIEGRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNHYASIDTLP
AGSIVGTSSLRRQCQLAAERPDLVIRSLRGNVGTRLGKLDNGEYDAIILAAAGLKRLKLE
TRIRQPLSPEQSLPAVGQGAVGIECRLDDEWTKALLAPLNHTETAVRVRAERAMNTRLEG
GCQVPIGSYAELRDGELWLRALVGAPDGSRVVRGERRGRPEEAESLGVSLAEELLDNGAR
DILAAVYDGEAPR
>I6JKH1|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis PY-59|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>G7AJJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-28A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>E7UQ04|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4100B|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>G7W5N3|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfosporosinus orientis (strain ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628)|TrEMBL
MKNIRIGTRDSQLAMWQAKWVQSQLTKLYPHLNFELVAMKTKGDKILDVPLSKIGDKGLF
TKELELGLLNNELDMAVHSLKDMPTLLPPGLVISACCEREEPRDVFLSKNGVLLEDLPSG
AIIGTSSLRRKSQLKHYRPDLKFMDLRGNLQTRWRKLQESEMEGIILAAAGVKRLGWEER
ITQILPESIMLSAVGQGSIAIEIDEKRSDIADLLSLINHTPTEQAVRAERTMMRRLEGGC
QVPIGALGQTVEGEIVLRGMVASLDGTRLIKADAKGSDPEAVGIEVANKLIELGATSILA
EIR
>I3UBM8|hydroxymethylbilane synthase|EC 2.5.1.61|Advenella kashmirensis WT001|TrEMBL
MTELKKLTIATRASRLALWQAHHVRDLLLAQYPQLQVELLELTTKGDQILDRTLSKIGGK
GLFIKELETALVDGRADLAVHSLKDVPVDLQSPFTLAAILERADPTDAFVSPTYHQLSQL
PAGAVVGTSSLRRESQIRAAYPHLVVKPLRGNLDTRLSKLDNGDYDAIVLATAGLQRLGL
GDRIASRLEVSESLPAAGQGALGIEVLESRTELLEILAGLADPATTACVTAERAVSRTLG
GSCQVPIAAYATLTDNAVTLNALVATPDGSRVLRSTRTSGAEGADQLGVEVAQALQEQGA
DQILAALHEASQNDADKA
>E8PJJ2|hydroxymethylbilane synthase|EC 2.5.1.61|Thermus scotoductus (strain ATCC 700910 / SA-01)|TrEMBL
MRVIVVGTRGSALALAQTRFVVERLKESWPEAEFKVKTIKTRGDQGANPMEQAIFVKELQ
EALLSREIDIAVHSLKDLPTEEPPGLKIAAIPRRQDPRDAFLGKVYKRLEDLPEGAVVGT
SSIRRKAQILAHRPDLVVKDLRGNVDTRLAALGNGEYDGIILAAAGLIRLDLRNRIDQFL
EPEVLLPAPGQGALALEVRQGDDLAEELCYALHHHPSHDRVRAERAFLKGLGAGCLAPVG
ALAQVAEDGTLLLEGMVLTPDGKSFIRAEIEGDASEAEELGLELAQDVLEQGGREILAQS
R
>Q4FVJ5|hydroxymethylbilane synthase|EC 2.5.1.61|Psychrobacter arcticus (strain DSM 17307 / 273-4)|TrEMBL
MSTMQQPALTTLNIATRQSPLALWQAEHIRDRLLVLYPEMTINLLKIVTKGDKILDTPLA
KIGGKGLFVKELEQALYDKQADIAVHSLKDVPMDLPEGLTLGVYCKRASPTDAFVSNTYH
SIDELPQGAVVGTASLRRQCQIKAYRADLQIKTLRGNVGTRLSKLDAGEYDAIILATSGL
QRLELNARIRSELDIDICLPAVGQGALAIECRADDDEVLKLLAPLNDDKARIRLIAERAL
NRHLQGGCQVPIAAYAVLQKADALAADNDDNGSVSNNNDAGDTLWLRGRVGQEDGSELLK
VEKRQTLTGSQAEQEAQANQLGIEVAEMLLEAGAGAILSAIYHPE
>I5EZB3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli FRIK1990|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H8LMM3|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia slovaca str. D-CWPP|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>D4HUK6|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia amylovora (strain CFBP1430)|TrEMBL
MSDKILRIATRKSPLALWQAKYVQQRLIDCHPRLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELENAMLSGHADIAVHSMKDVPVAFPQGLGLVAICERDDPHDAFVSNHYASVDSLP
AGAIVGTSSLRRQCQLSARRPDLVIHSLRGNVGTRLGKLDAGEYDAIILAVAGLKRLGLS
GRIRQVMPAEESLPAVGQGAVGIECRLDDMRTIGLLAALNHDDTACRVSAERAMNTRLEG
GCQVPIGSYALLEGDRLWLRGLVGSPDGSQMVRGERRGSRADAEKMGISLAEELLDNGAR
DILAAVYQGNPPA
>D9SNY2|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B)|TrEMBL
MKKIIRIGTRKSKLALMQTNIVIDAIKKKHPEINCEVVEMSTKGDEILDKSLLSFGGKGA
FVSEFEKAIKSGEIDLAVHSAKDMPMDLLTGLKIVAVTKREDPRDVLVTANNKDTINDFN
KTNKLIGTTSLRRKLQIKRLLNNVDTKDLRGNVQRRLEKLISGEYDGIILAAAGLKRLGL
LDDERINLNYLSVEDFIPAGGQGIIAVEGRAEEEFSFLKDSIHNEEAMYSLEVERYVMKK
LNAGCNEPIGAYSFIDKDTIFLDIIYEHNGKVSRKKGSDSIENRLKLTEKLVEEILQEVK
>F5S8N9|hydroxymethylbilane synthase|EC 2.5.1.61|Kingella kingae ATCC 23330|TrEMBL
MTAPKKLTIASRESALAMWQARHIQAQLQALYPDCQIDILGMTTQGDQILDKTLSKIGGK
GLFIKELETALQENRADLAVHSIKDVPMDLPEGFALVAIGERANPFDAFVSNQYARLEDL
PQGAIVGTSSLRREAQLRARFPHLNIKPLRGNVQTRLAKLDNGDYDAIILAAAGLERLEL
HERIRSVLSPADSLPAAGQGALGIEIAAHRADLVQTLLPLNHAKTAACVTAERALARALG
GSCQVPLAAYCTADDNGVLTLHGLVAHPDGSVMLTVQAQAPAEYADALGRAVAKKLADDG
AKDVIADVLANA
>G1C9M0|hydroxymethylbilane synthase|EC 2.5.1.61|Candidatus Kinetoplastibacterium galatii|TrEMBL
MNKKITIATRASKLASAQAEYVRDLIKSLYPEFMIDFLVIVTQGDKILDRALAKVGGKGL
FVKEIELALLHGDADMAVHSMKDVPAEMTDSLDICSILKRHDSRDVFVSNKYSSLDELPF
GAIVGTSSLRRESQLKSAYPQISVKCLRGNVDSRLKKLDIGDYSGIILAAAGLERINLGH
RISSYIDTSISLPAAGQGAIGIQIRNDRSDIRDLVASLSCIDTELCVKTERIVMKVLGGS
CQVPLAANAYIENGNIFLKAMVSSIDGKEVIRSNGSVSIDNWQNLGESVANDLLSKGAYK
ILHSV
>G0D823|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli NA114|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSLIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>D5ARR0|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)|TrEMBL
MEQMPSPNAPLKIGTRGSPLALAQAFETRSRLMAAFDLPEEAFEIVVIKTSGDNAALIAA
DKPLKEVGGKGLFTKEIEEAMLAGSIDIAVHSMKDMPTLQPEGLILDCYLPREDTRDAFV
SMKYNSLAELPEGAVVGTSSLRRRAQLAARRPDLKMVEFRGNVQTRMKKLGEGVADATFL
ALAGLNRLGMSEVAKSAIEPEDMLPAVAQGCIGIERREADTRAKMLLDAIHHAPSGLRLA
CERSFLLTLDGSCETPIGGLSVLEGDQIWLRGEILRPDGSETITGEIRGPAADGVALGAE
LAKQLLAKAPADFFCWR
>D3QX96|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O55:H7 (strain CB9615 / EPEC)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPHGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>I5ITD8|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA22|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I4HLR7|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 9808|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSQNQD
YQLDTLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDADPEVLEVLKVLEHAPSRDRCYAERA
FLRELEGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VREAGAGEILAEIFAEVGR
>H4FL46|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H43 str. T22|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I4V4L9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli CUMT8|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H7W569|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli LMG 9860|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>A5WHR2|hydroxymethylbilane synthase|EC 2.5.1.61|Psychrobacter sp. (strain PRwf-1)|TrEMBL
MTTSAHTTSLKTLNIATRKSPLAMWQAEHIKARLESLYPDLEVNLVTMVTQGDKILDTPL
AKIGGKGLFVKELEQALYDGRADIAVHSLKDVPMVLPEGLILGTYCKRETPTDAFVSNTY
DSLDALPQGAVVGTASLRRQCQIKAHRPDLIIKSLRGNVQTRLSKLDAGEYDAIILATSG
LKRVELSDRIKQEIDIDISLPAVGQGALAIECRSDDDAVLSLLKPLNDGQARIRLMAERA
LNRRLEGGCQVPIAAFAVIEKGAENDDTGSHNKTLWLRGRVGSEDGTTLLKADKRIALMG
NQADREAQAEQLGIDVADELLSLGADGILATIYNNKDKA
>I2C8J4|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus amyloliquefaciens Y2|TrEMBL
MRTIKVGSRRSKLAMTQTKWVINKLKELNPSYNFEIREIVTKGDRILDVTLSKVGGKGLF
VKEIEQALLHQEIDMAVHSMKDMPAVLPEGLVIGCIPKREDPRDALISKGHQKLDGIKEG
GIIGTSSLRRSAQILAERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKDD
VVSEFLEPDRCLPAVGQGALAIECRESDEELLKLFAQFTDEYTQRTVAAERAFLHAMEGG
CQVPIAGYASVNDRDEVELVGLVASPDGKTIYKETAAGHDPEEIGKRCAAMMSEKGAKAL
IDSVKQELDQDGK
>I5JAY2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA24|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D2RRS0|hydroxymethylbilane synthase|EC 2.5.1.61|Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734)|TrEMBL
MRTRGTLRLATRGSTLARRQASLVKEALEDRRYEVELVTVETTGDQIRDELIHRLGKTGA
FVRELDERVLEGDLDGAVHSMKDMPTEQPQDLVTAAVPERGPPGDVLITPDGSTLEELPD
GATVGTSSLRRRAQLLSERPDLEVEPLRGNVDTRLEKLLAPSLQEEHQERSEADKERKGN
AGDDDYEPEYDRTVDEWFDDLSELERQAMEREVETEYDAIVLAQSGLERSGLAHSVDYRE
LPTGTFVPAPGQGALAVTARDGETARDIQSAIDFPRSRVETTVERTILAELGGGCIAPVG
IYAVVQGEYVHATVNVFDRDGEESVEGSRDLPVEAHAEAAREFARDLADRGAAELIEAAR
EDAESDEGESVAEEDKPEGK
>I5XBG9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4437|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F2J9B3|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori 2017|TrEMBL
MGKLVIGSRGSELALWQANHIKERLKKECSMESEIRIVKTKGDKILDTPLSKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKFKRKDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLNVQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHANLMGDEVKIQAVLGLPNGKEVITKEKQGDKNKAFDLVRELLEEFLQSGAKEIL
EKAQLF
>B9MRJ4|hydroxymethylbilane synthase|EC 2.5.1.61|Anaerocellum thermophilum (strain DSM 6725 / Z-1320)|TrEMBL
MKKLRIGARDSKLSRIQVDIVARKIKQTLGIECEFVPIKTKGDIDKTKSLKDFQSPGVFV
KEIELALLSREIDLAVHSLKDLPCEMDSNFDIVAVVEREDPRDVLVSKDGVGFYQLKPNA
KIGTSSLRREVHLKNLREDIQVVNIRGNIETRLSKIESEGLDGVVLAYAALKRLNLDSHV
SYVFDINEITPCPGQGAICIECLEDSPYKSILSKINDVNAYIQTQFERLVLKLLGGGCHS
SIGVFCKTDQDKIYAFASLLRGDKLVKASIEGDKADFLSLANKLSNMLKS
>C8WXM9|hydroxymethylbilane synthase|EC 2.5.1.61|Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A)|TrEMBL
MRTLRVATRRSALALTQTNHVVDLLKQVAHGVEFELVPIRTRGDEIVDRALSEVGGKGLF
VADIEDALATGQADLAVHSLKDVPFELRDGLTIGAVPPREDPRDALISRTGQGLFDLPPG
ARVGTSSLRRQAALRRLRPDLCVETLRGNVDTRLRRLEEGQFDAIVLAASGLHRLGLAER
ITEYLPVDRFVPAVGQGALAIECRAEDDEVMRHLAAIADPDATRAVEAERAFLSRLEGSC
QVPIGAYAEPVGHELRLIAFVADPSGIHHLQLERTGDEARALGVAMAEEMLRQGAEDWLK
PGRGG
>E0N4A0|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus curtisii subsp. curtisii ATCC 35241|TrEMBL
MQTIGSTERPLVIGTRASALALTQTRAVASDLEQRGLHVQVQTFTTEGDINRASLASLGG
VGVFAAALRVALLEGHCDLVVHSLKDLPTVPVDGLVVAATPTREDPGDVLVARDSLSLAD
LPAGSRLGTGSPRRARQIAVARPDIELVDIRGNVPTRVGRVKGLAAVAEQAGLPSGKAAE
DLDGVVLARAGLRRLGMDDAITDSLEGTVIPAGGQGALALETRSELLDSDEGRNFAQILK
FVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGVVTWDKHTEAPSGRLELTARVIGNQGE
VLEVNGETTVLLGAEAAQRDFALAAAEQLGVDLAGELLEAGAATIADLKAAKSASTQTDA
NQTICNEKELWGE
>E0N4A0|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus curtisii subsp. curtisii ATCC 35241|TrEMBL
MQTIGSTERPLVIGTRASALALTQTRAVASDLEQRGLHVQVQTFTTEGDINRASLASLGG
VGVFAAALRVALLEGHCDLVVHSLKDLPTVPVDGLVVAATPTREDPGDVLVARDSLSLAD
LPAGSRLGTGSPRRARQIAVARPDIELVDIRGNVPTRVGRVKGLAAVAEQAGLPSGKAAE
DLDGVVLARAGLRRLGMDDAITDSLEGTVIPAGGQGALALETRSELLDSDEGRNFAQILK
FVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGVVTWDKHTEAPSGRLELTARVIGNQGE
VLEVNGETTVLLGAEAAQRDFALAAAEQLGVDLAGELLEAGAATIADLKAAKSASTQTDA
NQTICNEKELWGE
>H4H8X4|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1835|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E7WDU6|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 495297-4|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H5L0Z7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC13A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E0E4W2|hydroxymethylbilane synthase|EC 2.5.1.61|Peptostreptococcus stomatis DSM 17678|TrEMBL
MKLIVGTRGSALALAQTDSIISLVLDKFPDLEIEKKIIKTKGDKILDKSLDKIGDKGLFV
SEIERELLEGTIDFAVHSLKDMPTKISPGLKLAQTPERQDPRDVLVINPKHQLRPEDIMD
WLRSSQGLKIGTGSKRRTSQLKRINESIQPMMIRGNIGTRLEKLVSQDLDAIVLAAAGIN
RLGMDGLNLYHFSYEEMIPACGQGALAIEVRSNDENTDRIFDFLADDQACMEIEAERTFL
EVINGGCHVPVGATVKKVGNKWVLMGMYGREDCSSIVYGQLDFEPSLGGAKKVGQDLASY
LIKSLEDRDK
>Q2JKN8|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain JA-2-3B'a(2-13))|TrEMBL
MRIASRKSELALVQTQWVMGQLQEHHPGLPLELNTLSTQGDIILDVALAKIGDKGLFTKE
LEVSLLNGSSDLAVHSLKDLPTRLPEGLVLGAITRREDPLDALVVGEKFRDYRLATLPEG
TVIGTSSLRRLAQLRHAFPHLHFKDVRGNLNTRLAKLERGEYDGLILAVAGLKRLGKADR
IHEVLDPGVSLYAVGQGSLGIECRQGDERILELIRPLADAEATARCLAERAFLRALEGGC
QVPIGVHSQVQGEALHLTGMVADLDGRRLIRDTQTGSTADPEAVGMALAEKLKQQGADEI
LQAIFAQARR
>F9KQL7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21266|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H3NSS7|hydroxymethylbilane synthase|EC 2.5.1.61|gamma proteobacterium HIMB55|TrEMBL
MNSITIATRESPLALWQAHFVEAELKRHHPGIEVKLLGMTSRGDQLLDKPLYKVGGKGLF
VKELETALMDERADIAVHSMKDVPMELPPGLTLGVICEREDPRDALVGVDSFDSLPHGAK
LGTSSLRRSCQVMQRRPDLDIGFLRGNVNTRLAKLDAGEFDAIILACAGLKRLGFDDRIG
AAIDEDFLLPAGGQGAVGIEYRSSDASVAELLAPLAHDETARRVIAERTVVRKLDGGCDV
PIASFAVTEGDSLWLRARVGSPDGANVIAAEARGTDPEALGLEVAEALLEMGAAEILTAA
RS
>C5BBD0|hydroxymethylbilane synthase|EC 2.5.1.61|Edwardsiella ictaluri (strain 93-146)|TrEMBL
MQSMTTATQPTLRIATRQSPLALWQAHYVRDQLLAQWPQLTIELVPMVTRGDVLLDTPLA
KVGGKGLFVKELELALLEGRADIAVHSMKDVPVAFPDGLGLVTICQREDPRDAFVSPRFA
SLEQLPPGSVVGTSSLRRQCQLRAARPDLQIRDLRGNVGTRLAKLDAGDYDAIILAAAGL
KRLQLEDRIRTPLTPEQSLPAVGQGAVGIECRLADDATRRLLAPLNHAETALRVCAERAM
NTRLEGGCQVPIGSYAEIDGDRLWLRALVGAPDGSLMICGERRGPLAQAEAMGTALADEL
LARGARAILDAVYCQKA
>G1ZC45|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 2534-86|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQNAEQMGISLAEELLNNGAREILAEVYNGDAPA
>E1QF49|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / VKM B-1802 / 2st14)|TrEMBL
MPKLIIATRGSELALAQARWAARQLSALSPGLEVELQLFKTKGDKILDAPLAKVGGKGLF
VKEIEDALLDGRARVAVHSMKDMPAELPPGLCIAAVSRREDPRDVLISRDGLGLDELPAT
PRLGTSSLRRQAQLLARRPDAMVVSVRGNVQTRLRKLEELGLDAIVLAAAGLDRLGLSDP
RRVDLAPELMLPAVGQGALAIEARADDAFCLELCARLAHQPTAVAVEAERAFLGRLEGGC
QVPIAGHAVVDGDEIVFEGLVASLDGKRLIRRRAVGRADEAGPLGLAVAEEILADGGRQI
LAEVYGRGPQ
>F9Q8X1|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus pittmaniae HK 85|TrEMBL
MLQNNLLKIATRQSPLALWQANFVKHQLETLHPGLRVELVPMVTKGDVILDSPLAKIGGK
GLFVKELEAALLDGRADIAVHSMKDVPMEFPQGLGLSVICRREDPRDAFVSNKYAALADL
PAGAVVGTSSLRRQCQLKQLRPDLQVHSLRGNVGTRLSKLDQGEYDAIILASAGLIRLGL
AERIRSFIEVEQSLPAVGQGAVGIECRIDDLVVQQLLAPLADQQTTLCVLAERAMNRRLQ
GGCQVPIGGYAIIENEQLWLRALVGELDGSQIIRAEGRGDLTTAEQLGVQIAESLLAQGA
GQILAKVYG
>H2GLL1|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain BH8)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLAELPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>B5C649|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Saintpaul str. SARA23|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>B4AM17|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus pumilus ATCC 7061|TrEMBL
MRTIKVGSRRSKLAITQTKWVIQKLSELNPSYSFEIKEIVTKGDQILDVTLSKVGGKGLF
VKEIEQAMLNHDIDMAVHSMKDMPAALPEGLVIGCIPEREDVRDALISKDHLRLHELPKG
AIVGTSSLRRSAQLLQERPDLNIKWIRGNIDTRLEKLKNEEYDAIILAAAGLSRMGWSKE
VVSEFLSPETCLPAVGQGALSIECRGDDEELLQLLAQFTNEYTKKTVLAERAFLKQMDGS
CQVPIAGYATINERDEIELTGLVASADGHTIIRETVSGSDPEAIGTACAKQMADKGAKDL
IDKVKKDLSSQ
>H5BYI0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC9B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q1YY78|hydroxymethylbilane synthase|EC 2.5.1.61|Photobacterium profundum 3TCK|TrEMBL
MNALSTISELSSSPLNGTISVINANLMDPIFMTDKPIRIATRKSPLAMWQAEFVQAELEK
AHPGLVVELVPMVTKGDIILDTPLAKVGGKGLFVKELEVAMLEGRADIAVHSMKDVPVEF
PEGLGLVTICEREDPRDAFVSNTYNSIAELPAGSIVGTSSLRRQCQLRAQRPDLIINDLR
GNVNTRLRKLDEGQYDAIILACAGLMRLEMHDRIRSAIEPEESLPAVGQGAVGIECRLDD
HRVRALLATLNHPETATRIFCERAMNNHLQGGCQVPIGSYSELQGDQIWLRALVGEPDGS
KMVRGEITGAAIDGEALGTQLAEQLLADGAKEILDELYGNA
>H5IRE0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC12A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D0K2E4|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain 52)|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSMKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEKSAFCCHLEREFVKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKVQLF
>C8NSH0|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)|TrEMBL
MTLRIGTRGSKLATTQAGHMRDRLKHFGRDAELTIVTTPGDVNMSPVERIGVGVFTQALR
DALVADEIDVAVHSFKDLPTAPDPRFHLVVPTRADARDALIARDGLTLEELPEGAKVGTS
APRRISQLKALRPDLEILPLRGNIDTRMGKVTSGELDAVVLAFAGLSRVGMQDRATQVFD
PDMLMPAPAQGALAIECRVEDEDIITGLNMLMHADTYVTAVAERTVLNRLEAGCTAPVAA
HATLDGYAGDTMTLTAGVFALDGSEQLVFSAQGAGERPEELAEQVAAQLIEQGAATLLG
>F7UP15|hydroxymethylbilane synthase|EC 2.5.1.61|Synechocystis sp. (strain PCC 6803 / GT-S)|TrEMBL
MTVSTSAPTVRIGSRKSQLALVQTYWVQEELQKHFPDRQFDVETMETQGDKILDVALAKI
GDKGLFTQELEDGMLGKRTDLAVHSLKDLPTNLPAGLMLGCVTKRVNPADALVLNAKHQG
KDLASLPEGAVIGTSSLRRLAQLRYHFPHLTFKDVRGNVNTRLAKLDSNEYDAIILAAAG
LERLDMANRIDQLIPPEISLHAVGQGALGIECREGDQEILSLLKVLEDENSRDRCLAERA
FLRQLEGGCQVPIGVNTHLDGDNLTLTGMVASLDGQRLIKDTLSAPRKEAEKLGQDLALK
LREQGAGEILAEILAEAGRG
>F2I2U3|hydroxymethylbilane synthase|EC 2.5.1.61|Pelagibacter sp. (strain IMCC9063)|TrEMBL
MIAKQKLIIGSRGSRLSLAQSEHFKDELLLANPDLRPDQIELKVIKTSGDKFKTENLASM
GGKGLFVKEIEQELLENNIDCAVHSLKDVPTFGVPSLKLAAFLKRKDERDAFISPVAKSF
ETLKPGSTVGTSSVRRIAQLKKLRSDLNIVSMRGNIDTRIEKVKEGIYDSIVLAYAGLKR
LGFHTHVSEILDKEKMLPAAGQGVVTIQCRSNDGELIKLLKSVNDKETEIIVSAERSFLH
RVNGACDTPVAVNAVLNDDGEVFIQAEILSLDGKKVFNAHRTGISEKAVSIGLDVAEEIL
DKAGHDFVVSETKLAHTIHKT
>B7QXY2|hydroxymethylbilane synthase|EC 2.5.1.61|Ruegeria sp. R11|TrEMBL
MTQIDLPSPASPLKIGTRGSPLALAQAYETRARLAAAFDLPDDAFEIVVIKTTGDNQALI
AADKPLKELGGKGLFTKEIEEDLLSGAIDIAVHSMKDMPVQQPDGLVLDTYLPREDVRDA
FISPSLTSIHDLAKGAVVGTSSLRRRAQLLHRRPDLNVVQFRGNVQTRLRKLSEGVAECT
FLAMAGLNRLAMADVPANAIETNDMLPAVAQGAIGIERRTSDNRAADMLAAIHDQQTGQR
LAAERAFLAALDGSCETPIAGLAELDGTTLRLRGEVLRPDGSEAISDDQRCPIEDGAELG
RAMAAKLLDQAGEGFFDWKR
>E5R6U6|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain ECT-R 2)|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>F3RTM1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio parahaemolyticus 10329|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSSIDEL
PQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EDRIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEVRGHRKDGEALGIQLANELLDNGA
RDILTKLYADHD
>Q4JSX5|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium jeikeium (strain K411)|TrEMBL
MSITSNSANNASNATAARQTADGDRTFLIGTRRSALATTQTSHVRDGMQSAGYAAELHLV
HTPGDASQAAQIPVAQIGVGVFTETLRKALEAGECDVAVHSFKDLPTAPDPRFRTVVPRR
VDPREVLVSRNNQPLLELPQGAKVGTSAPRRVSQIRAVRPDLELMPLRGNIDTRMGRTEK
DLDAVVLARAGLERVGQLERAAESIDPSTIMPAPAQGALSVEVRADDEAAWQAVRHLDHL
PSHMAAVAERAVLSTLEAGCTAPVAAYSEWVQQEGTADGAVDGTVDGTEKHYVLRVFGGV
FAMDGSRKLVRSSEAGFDISEPTADEGFPAAEEPRWREYIDAARAIGIDIGRALLEDGAA
ELVAEVD
>F3TBI7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21172|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>F0MUE2|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup B (strain M01-240149)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGVVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVILQADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>H8A1M5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1997-1|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>F0A705|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis M6190|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLQADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>F5QQH1|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri 4343-70|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLCALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGEAPA
>H5Q6R0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC15B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHKTALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E1CUD2|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio parahaemolyticus Peru-466|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSNINEL
PQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EDRIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEVRGHRKDGEALGIQLANELLDSGA
RDILTKLYADHD
>H0LMZ4|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035278|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>F5KXM4|hydroxymethylbilane synthase|EC 2.5.1.61|Veillonella parvula ACS-068-V-Sch12|TrEMBL
MRDHIRIGTRKSALALWQAEHISAELQRLYPNITVELVHFNTKGDRILEKPLAQVGGKGL
FTAELEEAMHKGDIDIAVHSLKDMPTELPEGLTLGAISAREVPYDALVSPVYKTLDKLPQ
GARVGTSSLRRQAQLLHARPDLKVEVIRGNVQTRLSKIETEKLDGVILAQAGLKRLGLED
QITQVFKADEMIPAVGQGALAIECRADDTEMLDMLDPINDEATRYAVEGERSFLRQLNGG
CQVPMGVHGTINKGQLTLKAMIASLDGKTVYEGEISGPAKKGEILGKNLAKALYEEGGKR
IVDALIEEGIIK
>F3UJE7|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK1059|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKKLHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISKREDVRDCLIFRQAGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLTFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRSLLATVQDEKTAAEVAVERAVLAQM
NADCTFPIAALAQKKGQDYQLEAMLAKEDGQCVFVSLQGQDGQQLAEQAVRQLADKGAVG
MPWLKK
>A5F4J1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae serotype O1 (strain ATCC 39541 / Ogawa 395 / O395)|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>F0T3M3|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydophila psittaci (strain ATCC VR-125 / 6BC)|TrEMBL
MLSACYNDPFLSDFCLGRRPLRIASRKSTLAQAQVHECVRLLRSWFPKLWIQIHTISTRG
DKDKTTPLRLVENSQFFTDAVDKLVIRGNCHLAVHSAKDLPDPPATPVVAITKGLDPSDL
LVYAERYLWKRFPKVPRLGSSSLRRGETLKTLFPEGRILDIRGTIEERLEQLENGKYDAI
VIAKAAILRLHLHLPYTKVLPPPYHPLQGRLAITAGKDIEAWKTFLLPLNTATTSQETLL
SPNVI
>H8FTY5|hydroxymethylbilane synthase|EC 2.5.1.61|Phaeospirillum molischianum DSM 120|TrEMBL
MTAKPNTHPTIRIGTRGSPLALAQTYETRERLAAAWPDLAQPPVGGVDPVEIEVIKTTGD
MVLDRPLSEIGGKGLFTRELDDAMLDGRIRIAVHSMKDVPTYLPDGIVLPCILPREDVRD
AFICLKAKSIADLPAGSVIGSSSLRRGAQILNRRPDLKVVNFRGNVQTRMRKLEEGVVDA
TLLAMAGMRRLGLQQHITGSIETEDMLPAVAQGAIGITCRADDEDALRYLAPLNCQDSFD
RVTAERAFLTKLDGSCRTPIAALATLDGDTMFFRGLIVSPDGKALHSTSRTGSRADGVAM
AIDAAEELFKAAGPGFFDFMTS
>E4W8H5|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus equi (strain 103S)|TrEMBL
MSTDAAASPATDLNVGPDSRTLRIGTRGSLLATTQAGHVRDALIAAGHPAELVIIKTKGD
VTAGPVQRIGVGVFVAELREALVAGEVDVAVHSYKDLPTAQPDDLTIAAVPTREDPRDAL
VARDGLVLGELPPGSRIGTSAPRRRAQLRAMGLGLEIEPLRGNIDTRLGKVASGELDAIV
IARAGLSRIGRTERITETLEPVQMLPAPSQGALAVECRSDNPDLIAILGELDDHATRAAV
VAERALLAELEAGCTAPVGAIAEVVESLDDDGRVFEELSIRGCAAAIDGSDVIRASLVGS
PERADELGRAVARELLDLGARDLMTIAEDGDADA
>G2U5V8|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa NCMG1179|TrEMBL
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAE
AILEAVYGEAGHP
>F0G2T6|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia sp. TJI49|TrEMBL
MNSEILSAGPKQAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQ
ILDRTLSKVGGKGLFVKELENALADGRADLAVHSLKDVPMALPDGFSLAAIMSREDPRDA
FVSNDYASLDALPAGAVVGTS
>H7TI22|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 132-6|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>Q8I5V3|hydroxymethylbilane synthase|EC 2.5.1.61|Plasmodium falciparum (isolate 3D7)|TrEMBL
MHLLSFLSFIIWFIHCTAKRHEYSIKKYFLNSHNFCKIKPDPFRKDTLKKRLYSSDGIKD
EIIIGTRDSPLALKQSEKVRKKIMSYFKKMNKNINVTFKYIKTTGDNILDSKSVGLYGGK
GIFTKELDEQLINGNVDLCVHSLKDVPILLPNNIELSCFLKRDTINDAFLSIKYKSINDM
NTVKSVSKTEDIHHINKKDSDHNNDTLCTIGTSSLRRRSQIKNRYKNIYVNNIRGNINTR
IEKLYNGEVDALIIAMCGIERLIKKANLKHLLKNKEQKNICQPFLLKCNNKKCIDLCHVN
IQKLNKNLIYPALGQGIIAVTSHKKNYFISSLLKNINNKKSEMMAQIERSFLYHIDGNCM
MPIGGYTNMRNEDIYLHVIINDIHGYNKYQVTQKDTLYNYKEIGPNAAIKMKEIIGTEQF
NKIKAEAELHLLNNK
>I0WB58|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus imtechensis RKJ300|TrEMBL
MSAVGTRTLRIGTRGSELATTQAGTVRDALISAGHDAELVIIKTKGDQSMESVEKIGVGV
FTAELREALADGRVDVAVHSYKDLPTAPDERFTIAAIPPREDPRDALVARDGLVLGELPA
GSKVGTSAPRRTSQLRALGLGLDIRPLRGNLQRRLGKVESGELDAVVLARAGLARIGRLD
LITESIEPVQMLPAPAQGALAVECLSANTALVAILSELDDPNSRAAVTAERALLAELEAG
CTAPVGAIAEVVESLDDDGRIFDELSVRGCAAAIDGSDVIRTGAVGSPENAEELGRSVAR
ELLELGARELMNVTEAGDADV
>I0WB58|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus imtechensis RKJ300|TrEMBL
MSAVGTRTLRIGTRGSELATTQAGTVRDALISAGHDAELVIIKTKGDQSMESVEKIGVGV
FTAELREALADGRVDVAVHSYKDLPTAPDERFTIAAIPPREDPRDALVARDGLVLGELPA
GSKVGTSAPRRTSQLRALGLGLDIRPLRGNLQRRLGKVESGELDAVVLARAGLARIGRLD
LITESIEPVQMLPAPAQGALAVECLSANTALVAILSELDDPNSRAAVTAERALLAELEAG
CTAPVGAIAEVVESLDDDGRIFDELSVRGCAAAIDGSDVIRTGAVGSPENAEELGRSVAR
ELLELGARELMNVTEAGDADV
>I0RZ31|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium xenopi RIVM700367|TrEMBL
MIRIGTRASRLATTQAGSVRDALVARGHPAELVTITTEGDRSSAPIATIGVGVFTTALRE
AIAEGRVDAAVHSHKDLPTADDPRFVVAAIPRREDPRDVVVARDGLLLAELPHGSVVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLSRVSSGDLDAVVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRADATELAALLAELDDADTRAAVTAERALLAELEAGCSAPVGA
LAEVVESIDEDGRVFEELSLRGCVATLDGSDVIRASGIGRPDRARELGLSVAAELFALGA
RELMSGAR
>I0RZ31|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium xenopi RIVM700367|TrEMBL
MIRIGTRASRLATTQAGSVRDALVARGHPAELVTITTEGDRSSAPIATIGVGVFTTALRE
AIAEGRVDAAVHSHKDLPTADDPRFVVAAIPRREDPRDVVVARDGLLLAELPHGSVVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLSRVSSGDLDAVVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRADATELAALLAELDDADTRAAVTAERALLAELEAGCSAPVGA
LAEVVESIDEDGRVFEELSLRGCVATLDGSDVIRASGIGRPDRARELGLSVAAELFALGA
RELMSGAR
>C0QU69|hydroxymethylbilane synthase|EC 2.5.1.61|Persephonella marina (strain DSM 14350 / EX-H1)|TrEMBL
MRIRIGTRKSKLALWQANYIADQLKKHFPDLEVELVKIVTKGDKILDVPLAKVGGKGLFV
KEIEEAMLRNEIDIAVHSLKDVPTYFPEGLGLVAITEREDPRDAFLSVKYNSIEDMPEGA
VLGTSSLRRKAQIMMKRKDIRIEDLRGNVDTRIRKLEEGQYDGIILAYAGLKRLGLEGKV
RQILQPDYMIPAVAQGFLGIEARLDDEKTREIVSVLNHRESEIRAKAERAFLKTLEGGCQ
VPLAGYSEIVNGKLKITGFVSDLTGDRVFRDSMEGSLEDAESLGVKLAEKLLSDGAKEVL
EEIYSGSE
>F2NEV4|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2)|TrEMBL
MKNHLRIGTRGSALALAQAAWVQQQIQGRYPQITVDLEIIKTTGDKIQDVALAKIGGKGL
FTKEIEMAILSGEVDLGVHSMKDVPTEIPLGLVIGITTVREDPRDAFISRKYRSLAEIPL
GGRIGTGSLRRRAQLLHLRPDLEIVPLRGNVDTRLRKLTEADLDAIILAAAGLHRLGRAA
EITAILPETQMLPAIGQGALGLEYRQDDAVTMELLEFLDDPETRVAVAAERAFLARLEGG
CQVPIAAMGTLKKGELFLDGLIGDLAGSRIYREQLSRPPAAAADLGQQLAETLLKRGGAQ
ILSEVYGRVFD
>D5PZC2|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium difficile NAP08|TrEMBL
MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDLIQNVSLDKIGDKGLFV
KEIEQQLLYGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPRDVLILREGYKNLDDLPRG
AVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDENMHGIVLAASGIIRANLQDK
ISSYLPVDVVIPAPAQGALAIEIRSNDSKIEGIVNSLKDENTEIQILAERGFLDGVNGSC
HIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDGDISSPRELGLKLAKLVLKEYENYE
G
>E2S5J2|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium pseudogenitalium ATCC 33035|TrEMBL
MFQIGTRGSKLATTQAGHVRDWLIDAGFDSQLHIVTTAGDVNMAPVERIGVGVFTQALRE
ALYAGECDIAVHSFKDLPTAPDERFRLVVPQRQDSREALVARDGLSLAQLPQGARVGTSA
PRRISQLAALRPDLEIRPLRGNIDTRMSKVTDGELDAVLLAYAGLLRGGYADRATEIFEP
SVFMPAPAQGALAIEAVAGTEAAAALDAIVDDRASAAAAGERAVLARLEAGCTAPVAATS
RWDGDQLTVRGGVFALDGSRQLTATASGSAAEAADLGARISDELFAGGAAELLGK
>E2S5J2|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium pseudogenitalium ATCC 33035|TrEMBL
MFQIGTRGSKLATTQAGHVRDWLIDAGFDSQLHIVTTAGDVNMAPVERIGVGVFTQALRE
ALYAGECDIAVHSFKDLPTAPDERFRLVVPQRQDSREALVARDGLSLAQLPQGARVGTSA
PRRISQLAALRPDLEIRPLRGNIDTRMSKVTDGELDAVLLAYAGLLRGGYADRATEIFEP
SVFMPAPAQGALAIEAVAGTEAAAALDAIVDDRASAAAAGERAVLARLEAGCTAPVAATS
RWDGDQLTVRGGVFALDGSRQLTATASGSAAEAADLGARISDELFAGGAAELLGK
>I6KCR4|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis PY-100|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>F7XP44|hydroxymethylbilane synthase|EC 2.5.1.61|Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5)|TrEMBL
MIIGTRGSSLALAQANIVAGILEKRGVITSRQIIKTTGDSFTDRPLHELNGVGAFVRELD
ERIISGEIQIAVHSMKDLPTKRPEELSTSAVLMRDSPHDILITSDGSKLDDLPQGAIIGT
TSMRRRAQILRYRPDLNIQDLRGNIDTRLKKLQAGHYDAIMLAEAGLQRMKWDIDIDFER
LNPDDFCPSANQGTIAVVTLKGSEADTLVSMIDHAPSRIETQVERIITNEVEGGCVAPVG
AFAKISGSGNEIFARAEVLSLDGSEYIRVENEIPRDNYREHALELGRELVGKGAKELVAE
AVCQLSSVRGQQLK
>G6ZAB9|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-19A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>I0TJJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-250|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>F4DHI1|hydroxymethylbilane synthase|EC 2.5.1.61|Aeromonas veronii (strain B565)|TrEMBL
MKARAKGGNIDFLLKMKQLIDMAARTLKIATRKSPLALWQANFVKDRLEALHPQLQVELV
PMSTQGDKILDTPLAKVGGKGLFVKELETAMLEGRADIAVHSMKDVPVEFPEGLGLHTIC
EREDPRDAFVSNRFKAIAELPQGAVVGTSSLRRQCQLRAARPDLVIRDLRGNVNTRLAKL
DAGEYDAIILAAAGLKRLEMAHRITAFIEPEQSLPANGQGAVGIECRLDDVELHALLAPL
EHTETRARVLTERAMNRALQGGCQVPIGAYALVEGEQIWLRGLVGSPDGTQVIRDEIRGP
LADGEALGEQLAQRLLAAGADEILAEVYRA
>E5QUF4|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain TCH60)|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>Q3R8Z1|hydroxymethylbilane synthase|EC 2.5.1.61|Xylella fastidiosa subsp. sandyi Ann-1|TrEMBL
MPLLRIATRKSLLAMRQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLF
LKELELAMLRGDADCAVHSLKDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIG
ARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNGDYDAIVLACAGLRRLGLEQR
MTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRQCVVAERTMNRALHGSC
HVPVGAYASYGVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAEL
LAATA
>G4RKU2|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoproteus tenax (strain ATCC 35583 / NBRC 100435 / JCM 9277 / Kra 1)|TrEMBL
MKIRVATRGSKLSLLQTEMFLMRIKAVEPDVKFEIITVKTTGDLVQDRPLYEIGAKGIFE
KEVNMALLRGDADIAIHSLKDLPSVISDELVIAGFSERETPYDVLASKSGYNIYTLPPGA
RVGTSSVRRAAFLKRVRPDVNIVPLRGNLDTRVGKVLNGVVDAAILAEAGLRRLYGAGAP
LNLYRIRPEVIPPPPGQGIIAAVARRDDVGIIELLRRASDRRAAVEAAAERAFLKEVGAG
CHTAVGGIAIAGPLGIEFLAAYASLDGRRAVFVRVFGESPEEVGTRAGRRLKEAMSSEGL
KA
>E8EQ55|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 315731156|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H8B515|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 51037|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESILRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>D3LM89|hydroxymethylbilane synthase|EC 2.5.1.61|Micrococcus luteus SK58|TrEMBL
MTPLRIGTRGSALATTQTTHVAEALTERSGLAHELVVIRTEGDVTTGSLASLGGTGVFAS
ALRAAVLDGAVDAAVHSLKDLPAAQPETLEIAAVPARADLRDALCARDGLTLATLPEGAR
VGTGSPRRVAQLKALRPDLELVDIRGNVQTRLARVPGLEQHDDHAPAAAGSPRGDLDAVI
LACAGLDRLGLDHVITERIDPEVMVPAPGQGALAVEIRAEDESFLGRALLDPQAPVGRLH
AALELVDDRDTHVAVTAERALLRRLEAGCAAPIGAVARVSDGEAGAPRIEMTAMVAALDG
SRVLRRTSSVQLDPVPADVAGDPAAADEWLEDTLFVAAEALGVHVAEQFVAEGADLLPGT
VRGVDRGDGAPRPDDPA
>D3LM89|hydroxymethylbilane synthase|EC 2.5.1.61|Micrococcus luteus SK58|TrEMBL
MTPLRIGTRGSALATTQTTHVAEALTERSGLAHELVVIRTEGDVTTGSLASLGGTGVFAS
ALRAAVLDGAVDAAVHSLKDLPAAQPETLEIAAVPARADLRDALCARDGLTLATLPEGAR
VGTGSPRRVAQLKALRPDLELVDIRGNVQTRLARVPGLEQHDDHAPAAAGSPRGDLDAVI
LACAGLDRLGLDHVITERIDPEVMVPAPGQGALAVEIRAEDESFLGRALLDPQAPVGRLH
AALELVDDRDTHVAVTAERALLRRLEAGCAAPIGAVARVSDGEAGAPRIEMTAMVAALDG
SRVLRRTSSVQLDPVPADVAGDPAAADEWLEDTLFVAAEALGVHVAEQFVAEGADLLPGT
VRGVDRGDGAPRPDDPA
>A0KFH6|hydroxymethylbilane synthase|EC 2.5.1.61|Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)|TrEMBL
MKAPAKGGKIVFLLKMKQLIDMAARTLKIATRKSPLALWQANFVKDRLEALYPELQVELV
PMSTQGDKILDTPLAKVGGKGLFVKELETAMLEGRADIAVHSMKDVPVEFPEGLGLHTIC
EREDPRDAFVSNRFGQIDELPQGAVVGTSSLRRQCQLRAARPDLVIRDLRGNVNTRLAKL
DAGEYDAIILAAAGLKRLEMAHRITAFIEPEQSLPANGQGAVGIECRLDDHELHALLAPL
EHPETRIRVLTERAMNRALQGGCQVPIGAYALVQGEEVWLRGLVGSPDGSRVIRDEIRGP
LADGEALGHTLAQRLLADGADVILAEVYRA
>C7RNK0|hydroxymethylbilane synthase|EC 2.5.1.61|Accumulibacter phosphatis (strain UW-1)|TrEMBL
MNSANQAPPRLVIASRESRLAMWQAQHVSGRLTELYPQTAVDILGMTTRGDQILDRPLAA
IGGKGLFIKELEVAMQQGRADLAVHSMKDLPMEMPEGFALAAISVRENPCDAFVSNRFGG
LAELPANAVVGTSSLRREAMLRAGYPQLEIRSLRGNLDTRLRKLDAGDYDAIILAAAGLI
RLGLTDRIKAVLTPEQSLPAPGQGVLGIEVLSARVDLLTLVAPLNDVATAHCVRAERAFS
RALGGSCQIPLAAHAVLDSGALWLRGWIATPDGRHSLSGELRGLPEDDESIGCRLAQALH
ERGADAILRELATGQ
>F0T648|hydroxymethylbilane synthase|EC 2.5.1.61|Methanobacterium sp. (strain AL-21)|TrEMBL
MKVGTRGSSLATYQTKTIINELSIVTDEKIDVEIIKSTGDKIQNSQLYNIDAKGIFTREL
DDAVLDGTVDFAVHSLKDLPTELEGDLEIVAVPERESPNEVLVSKLGWDELPKGATVGTS
SIRREAFCNHHDKEFNIKPIRGNIDTRIKKVFSGEYDATIMAEAGLNRLGLTEYIKQRFS
IEYFTPAAGQGAIAVVARSDSDVKDDLQKINHLKSFQEVTAEKRVLLEMGVGCQSPLGVS
ARINENKLKLCAVLLTQEGKIVSRVMVEGSADKASNLGLKAAKLMMEDYI
>E6QMA3|hydroxymethylbilane synthase|EC 2.5.1.61|mine drainage metagenome|TrEMBL
MIRIGTRGSQLALWQANHIAALLRAHGQDVAIVVIKTTGDRLQEMTFAEVGSKGMFTLEI
EQTLAAGGIDLAVHSLKDLPTELPAGFVLAATPARVDPRDVFVSCNYESLRQLPAGTRVG
TSSQRRRAQLRHLRPDLEYVEFRGNVDTRLRKLAEDQVEAILLAAAGLDRLEKTEWVRER
LDPEQMCPAAGQGALGIECREGDTRILDALRFLDDAATRFAVTAERTALAALGGGCQVPI
GVHCRPIPTGSAGFEILGVVAEPYGSRLLRARATGEDARTLGQSVAKELLRLGAGELLGA
GIKP
>G7CHG9|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium thermoresistibile ATCC 19527|TrEMBL
MTQRDGVIRIGTRGSLLATTQAGVIRDALISRGHPAELVIISTRGDRSPDTPIEHMGVGV
FTAELREAILDGRVDAAVHSYKDLPTADDPRFAIPAVPPREDPRDVLVARDNLVLGELPA
GSLIGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVRNGELDGIVVARAGLARIGRLE
VVTETLEPVQMLPAPAQGALAVECRAEDTGLAAILAELDDSDTRAAVTAERVLLAELEAG
CSAPVGAIAEVVESIDEDGRVFEELSLRACVATVSGSDVIRASGVGTPGRARELGVSVAA
ELFELGARELMADRTEL
>G7CHG9|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium thermoresistibile ATCC 19527|TrEMBL
MTQRDGVIRIGTRGSLLATTQAGVIRDALISRGHPAELVIISTRGDRSPDTPIEHMGVGV
FTAELREAILDGRVDAAVHSYKDLPTADDPRFAIPAVPPREDPRDVLVARDNLVLGELPA
GSLIGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVRNGELDGIVVARAGLARIGRLE
VVTETLEPVQMLPAPAQGALAVECRAEDTGLAAILAELDDSDTRAAVTAERVLLAELEAG
CSAPVGAIAEVVESIDEDGRVFEELSLRACVATVSGSDVIRASGVGTPGRARELGVSVAA
ELFELGARELMADRTEL
>A5ULK8|hydroxymethylbilane synthase|EC 2.5.1.61|Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861)|TrEMBL
MNVGTRGSQLALAQTNQVCKDLASITNENIDVNIIKTKGDKITNSQLYNMDAKGLFTKEL
DKALLEEEIDFAVHSFKDLPTELDEELEIAAVPKRVAPNEVLISNKNWDELGPNSKLGTS
SLRREAFCNYHNKCFELKPIRGNIETRISKVNGSDLDATLMAQAGLIRLNLTQHIKTVFP
LDYITPAAGQGALAIITRKDSDKKEIISKLNDYQSRQEVFAEKQVLEELGVGCQWPIGAI
AQMKDKQFCIYSILLTKEGEVLKEHTEKGSIRDAVQFGKKIGKVFKDYV
>E1S7A0|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain 908)|TrEMBL
MGKLVIGSRGSELALWQANHIKERLKKECSMESEIRIVKTKGDKILDTPLSKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKFKRKDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLNVQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHANLMGDEVKIQAVLGLPNGKEVITKEKQGDKNKAFDLVRELLEEFLQSGAKEIL
EKAQLF
>D2RH82|hydroxymethylbilane synthase|EC 2.5.1.61|Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)|TrEMBL
MSERVVVGTRGSKLALAQTSKVVERLKEEGYSVEIRIIKSTGDIMKDKPLYEFKGSGAFV
RALEHALVRGEIDVAVHSYKDIPSNMLEGVTVSAVLERDSPYDAFIARNGESLEEIKPNA
VIGTSSLRRRAQLKLYRSDLRFENLRGNVDTRLRKLREGLYDAIVLAEAGIQRLGLNVKY
QRLPIERFVPPANQGIIAVQTRVGEEDLVKFMNHEETWIEAEVERIVMKTLGVGCAIPAG
IYAECRGKVRLIVQVIRDGREFKVIEELSRESAIEEAREIAENFREEVGLRA
>H7FHK4|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus saprophyticus subsp. saprophyticus KACC 16562|TrEMBL
MRKLVVGSRRSKLALTQSRQFIDKLKAIDPSLEIEIKEIVTKGDLIVDKQLSKVGGKGLF
VKEIQNELFNHGIDMAIHSLKDVPSVIPDGLTLGCIPDRENPYDAYIAKNHVPLNELPDN
SIVGTSSLRRGAQILAKYPKLQIKWIRGNIDTRLNKLETEDYDAIILAAAGLKRMGWSDD
IVTSYLDKETLIPAIGQGALGIECRSDDETLLSLLSKVHNQDVADCVTAERTFLTRMNGS
CQVPIGGYATKEADGTIEFTGLIMSPDGKERYQHTVRGIDPVALGEEVTKVLNEQGAYEI
IKALNEEQ
>E8CHH5|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 556152|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H8D0E9|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 23211|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHKIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPRGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>E0TV95|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus subtilis subsp. spizizenii (strain ATCC 23059 / NRRL B-14472 / W23)|TrEMBL
MRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGLF
VKEIEQALLNEDIDMAVHSMKDMPAVLPEGLVIGCIPEREDPRDALISKNHVKLSEMKEG
AVIGTSSLRRSAQLLIERPDITIKWIRGNIDTRLKKLETEDYDAIILAAAGLSRMGWKQD
VVTEFLEPDRCLPAVGQGALAIECRESDEELLALFSQFTDEYTKRTVLAERAYLNAMEGG
CQVPIAGYSVLNEQDEIELTGLVTSPDGKIIFKETVTGNDPEEVGKRCAALMADKGAKEL
IDRVKRELDEDGK
>B6ZPU2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. TW14588|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>H3VAF5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU118|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSIIPDGLTLGCIPDREIPFDAYIAKNHIPLEELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDVLLPAIGQGALGIECRSDDKELLNLLAKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIVQDNQIEFTGLIMSPDGKERYEHTTLGSDPVQLGIEVSRVLKKQGAYDI
IKKLNEAE
>Q1YSU2|hydroxymethylbilane synthase|EC 2.5.1.61|gamma proteobacterium HTCC2207|TrEMBL
MVDNVHLVNHSDGISVPQTIRIATRKSPLALWQAEFVKAKLLENHPDLDVQLVAMTTRGD
VLLDTPLAKVGGKGLFVKELEVAMLENRADIAVHSMKDVPMEFPPGLGLTVICEREDPLD
AFVSNRYANLAELPPGSVVGTSSLRRQCQIRAAFPDLQIKDLRGNVNTRLAKLDYGDYDA
IILASAGLIRLGMEARIASRLESELCLPAGGQGAVGIECRLDDQATIELLKPLEHSQTRI
RVTAERALNRRLEGGCQVPIACYAELDEAGESLQLRGLVGSVDGSLILQDQLSAPVAQAE
QLGIELAERLLAAGAGEILAEVYGAD
>B7GH32|hydroxymethylbilane synthase|EC 2.5.1.61|Anoxybacillus flavithermus (strain DSM 21510 / WK1)|TrEMBL
MEESMMRKIIVGSRRSKLALTQTNWVIEQLKQLGAPFEFEVKEIVTKGDQILHVTLSKVG
GKGLFVKEIEQAMLDGEIDFAVHSMKDMPAVLPDGLVIGCVPKREDHRDVLISKGHIPFE
QLPSGAIVGTSSLRRSAQLLAVRPDLQIQWIRGNIDTRLAKLQTDAYDAIILAAAGLHRM
GWAKEVITQYLPTDICVPAVGQGALAIECRENDAELLHWLNKLTDKQTERATRAERAFLQ
HIEGGCQVPVAGYAYVDEDAIVLTALVATPNGTEVLKEVVKGTEPEKVGTEAAKRLIERG
AKQLIERVLKELE
>B9JCG9|hydroxymethylbilane synthase|EC 2.5.1.61|Agrobacterium radiobacter (strain K84 / ATCC BAA-868)|TrEMBL
MVTGTVGNNGSKRMQTKPFRIGTRGSPLALAQAHEARDRLMAAHGLPEEMFEIVALTTKG
DRIADRTLAEIGGKGLFTQELEEKLTSGELDFAVHSAKDMATKLPEGLALTAYLPREDIR
DSVIGRTAPKLIELPHGATVGSASLRRQALIRRLRPDINVITFRGSVQTRLRKLEEGQAD
ATLLAVAGLKRLGKVDVITDILDPDEFPPAPAQGAIGIESRIGDKRMNDLLAAINDSPTF
DIVSCERGFLAALDGSCRTPIAGYAVCEGDHIRFFGMILTPDGQQVHTTTIEGNRRDAEA
LGTNAGQAIRAEAGSAFFEDWT
>B0JSD2|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa (strain NIES-843)|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSQNQD
YQLDTLPEGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDADPEVLEVLKVLEHAPSRDRCYAERA
FLRELEGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VREAGAGEILAQIFAEVGR
>H5A4D3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC8C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I5QU06|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW11039|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B9CAQ6|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia multivorans CGD2M|TrEMBL
MNSEILAAGPRPAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQ
ILDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMMLPDGFALAAIMQREDPRDA
FVSNDYASLDALPAGAVVGTSSLRREAMLRARYPHLQVLPLRGNLDTRLSKLDRGDYAAI
ILAAAGLKRLGLEARIRALLDVEDSPPAAGQGALGIEIAAHRADVAAWLEPLHDAQTALA
VEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTIDGTRVLTAEECASVVTVADAL
ALGRAVSDELEAQGALEIVRALLAGSQAGKGEA
>I0EC49|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori Shi112|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIRAVLGLPNGKEVIAKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKAQLF
>F3T5H1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21189|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H8C6G0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1798|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>F5YCL2|hydroxymethylbilane synthase|EC 2.5.1.61|Treponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9)|TrEMBL
MKNLIRIGSRESALAIAQTRIVMDAIARSHPELKLELVTMKTLGDLKPNLALENTGNGKA
IFTGALEDALARNEVDLCVHSLKDMAADTPKDLPIVALAKRGDPRDCLILPKDEPFEGFE
NLNRNYANQHNGKVPPPAGCSSLRRQIQFRALASAPDFSPIRGNVPTRINKLDSGQYGLL
ILAAAGLERLGLLPRAAYIFPVEKMIPAAGQGVLAVQGRKDDEYSFLKDINDPVTAEEAL
AERAFIKAAGGGCGSPAAAYARITGSEIHIQALLAAHSEIKPGAAFFRDEISGPREESQK
LAEELASRLLKIAGHA
>C8PGJ5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter gracilis RM3268|TrEMBL
MKNLIIATRGSVLALWQSKHIASLLNARGIQAQLKSMKTKGDKILDTPLAKIGGKGLFTK
ELEESMLRGESHIAVHSLKDVPVEFPQGLVLAAICAREDVRDAMISEKYSKFDELPRGAK
VGTTSLRRKMQLLSMRPDLEVISLRGNVQTRLRKLKDGEFDAIILAMAGINRLNLRAEVK
HVAPFEISQMIPAMGQGALGIEAVDEPQILRAIEFLKDERAIIETTVERDFVRVLEGGCQ
VPIGINARLEGENIHISAIVGLPDGSESIRQSIVAQKSQYQSVGAELARVFIEKGAKQLL
ARAEAMASL
>A3JE46|hydroxymethylbilane synthase|EC 2.5.1.61|Marinobacter sp. ELB17|TrEMBL
MSARNLRIATRSSALALWQAEFIKAELERLHSNVTVELVKIKTLGDKILDVPLAKVGGKG
LFVKELEEAMLDGRADLAVHSMKDVPMAFPEGLGLVAICERDDPTDAFISNHFSSLDDLP
LNAVVGTSSLRRESQLRANRPDLQIRVLRGNVNTRLAKLDAGNYDAIILASSGLKRLGFE
ARIRNCMPDTLSLPAVGQGALGIECRLDDQELRAMLEPLNHTDSADRVKAERALNTRLNG
GCQVPIAAYALLEDNDMLWLRGLVGAVDGSLIFRAEGRVHRSEGERLGRELAEDLLAQGA
DKVLAEVYGYTPT
>C1AZ43|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus opacus (strain B4)|TrEMBL
MSAVGTRTLRIGTRGSELATTQAGTVRDALISAGHDAELVIIKTKGDQSMESVEKIGVGV
FTAELREALADGRVDVAVHSYKDLPTARDERFTIAAIPPREDPRDALVARDGLVLGELPP
GSKVGTSAPRRTSQLRALGLGLDILPLRGNLQRRLGKVESGELDAVVLARAGLARIGRLD
LITESLEPVQMLPAPAQGALAVECLSANTALVAILSELDDPNSRAAVTAERALLAELEAG
CTAPVGAIAEVVESLDDDGRIFDELSVRGCAAAIDGSDVIRTGAVGSPENAEELGRSVAR
ELLELGARELMNVTEVGDADV
>F0I7G8|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK115|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVEQLKELHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSLLHIQPLETRLCLPAISQGALAVEYREEDEELRKLLATVQDEKTAAEVAVERAVLAQM
NADCTFPIAALAQKKGQDYQLEAMLAKEDGQCVFVSLQGQDGQELAEQAVRQLADKGAVG
MPWLKK
>I0LGJ7|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)|TrEMBL
MTLKIGTRGSKLATTQAGTIRDQLKHYGRDAELHIVTTPGDVNMSPVERIGVGVFTQALR
DVLHSGECDVAVHSMKDLPTATDPRFHLVVPTRADSREALIARDGLTLAELPEGAKVGTS
APRRISQLKAIRPDLEILPLRGNIDTRMGKVTSGELDAVMLAYAGLTRVGMQDRATEVFD
ADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAERTVLNRLEAGCTAPVAA
HATLDGYSGDTMTLTAGVYALDGSDQLVFSAEGDGARPEELGELVAQQLIDAGAANLLGD
RS
>H7RQD7|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 2685|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKILKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>C2IEE3|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae RC9|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>H2IF05|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio sp. EJY3|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSSVDEL
PQGAIVGTCSLRRQCQLKEYRPDLIIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLKL
EERIRSFIEPEQSLPAVGQGAVGIECRLDDERLLKLLEPLNHKDTEDRVLCERAMNLTLE
GGCQVPIGSYALLDGDNVWLRALVGEPDGSEIVRGEIRGHRKDGEALGIQLANELLDNGA
RDILTKLYADHD
>B9KLM2|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacter sphaeroides (strain KD131 / KCTC 12085)|TrEMBL
MPTPAEPLKIGTRGSPLALAQAYETRSRLSAAFSLPEEAFEIVVIKTTGDKVLDRPLKEI
GGKGLFTREIEEALLSGGIDIAVHSMKDMPTLQPEGLILDTYLPREDTRDAFITFAEGGL
ADLPQGATVGSSSLRRRAQLLNKRPDLQVVEFRGNLQTRLKKLNDGVARGTFLAMAGLNR
LKMNEVPRVPIEPEEMLSAVAQGAIGIERRTDDPRAQEMLAAIHDVPTGHRLAAERSFLL
KLDGSCETPIAGLAILEGDQLWLRGEILRPDGSESISGEIRGAIADAAALGSELASELLG
RAPADFFSWR
>B2IAW6|hydroxymethylbilane synthase|EC 2.5.1.61|Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712)|TrEMBL
MSRNSTIANPPIDQPLPRLRLGTRGSPLALAQAHELADRLARAHGFAKEAVAITIIRTSG
DMIQDRPLSLAGGKGLFTKELDQALIEGMVDLAVHSAKDLPTILPEDLIIAGYLPREDVR
DVWISPKAGHPRDLPPGSVVGTASLRRGALLKRLRPDLEVRLLRGNVETRLAKLAAGEVD
ATLLALAGLRRLGLADKATQVLAIEDFLPAAGQGAIGITTRRDDAATLALLAPILDPATH
VALAAERGFLTVLDGSCKTPIGAHATVEHDQVTLRGIVLRPDGSEWFEACESGPLESGSL
EAARELGETAARAILARLPEGFFQESAQENAQKNAKE
>A2TR68|hydroxymethylbilane synthase|EC 2.5.1.61|Dokdonia donghaensis MED134|TrEMBL
MSKTIRIGTRDSELALWQAKTVQKQLEDHGYTTELVPVKSTGDLILDKPLYELGITGIFT
KTLDVAMLNGTVDIAVHSMKDVPTALPIGIVQAAVLPRAETEDILVHKGAPDYKQACTIA
TGSLRRQAQWLNRYPNHKTTDIRGNVNTRLQKLEESDWTGAIFAKAGLKRINVLPENYEV
LDWMIPAPAQGAMLVVAMEEDAFSKEACAKLNDRTTALCTHIEREFLRTLEGGCTAPIGA
LAQEIDGAIRFKGVLFSLDGATKIEVEQVVSTENALGFGTDCALEVLDNGGRALMKEIKS
SLKK
>D5DLL8|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus megaterium (strain DSM 319)|TrEMBL
MRKIIVGSRRSKLALTQTKWVIEQLKKQGLPFEFEIKEMVTKGDQILNVTLSKVGGKGLF
VKEIEQAMLDEEIDMAVHSMKDMPAVLPEGLTIGCIPLREDHRDALISKNGERFEELPSG
AVIGTSSLRRGAQLLSMRSDIEIKWIRGNIDTRLEKLKNKDYDAIILAAAGLSRMGWSRD
TVTQYLEPEISVPAVGQGALAIECRENDHELLSLLQALNHDETARAVRAERVFLKEMEGG
CQVPIAGYGRILDGGNIELTSLVASPDGKTIYKEQITGKDPVAIGSAAAERLTSQGAKLL
IDSVKEELDK
>H5K5H4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC12D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F4N3Q4|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia enterocolitica W22703|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQVELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPIAFPEGLGLVTICERDDPRDAFVSINYAHLDELP
AGSIVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDKGEYHAIILAVAGLKRLGLE
TRIRYAMPAEESLPAVGQGAVGIECRLDDNFTRQLLAPLNHRETELRVCAERAMNTRLEG
GCQVPIGSYAELDGDTLWLRALVGAPDGSEIIRGERRGPAENAEQMGVELADELLSRGAR
EILAEVYQDNPPL
>E8BMW2|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 609460|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>E9RQX7|hydroxymethylbilane synthase|EC 2.5.1.61|Lactobacillus reuteri MM4-1A|TrEMBL
MTNKVIVGSRKSKLAMAQTELVIASLEKIFPDIKFEIKNVITEGDRNRHVSLAKIGGKGV
FVKEIEDELKDGTIDFAVHSLKDVMPILPEELVLGAFPKRVSPYDCLVSRKNLSSLNDLP
KGARIGTNSLRRQGQLLSIRPDLKIIPIRGNIDTRLRKIDTEALDGIILAEAGLTRLNID
LSSYHVLDLQNYIMPAVGQGCLAIECRKNDTRIRKMLDQINDEESAYCVQVEREFMRELG
GSCNFPIGGHAYAKNGQILFDGLIASPNGEHVIKETKIPANNSGVGKKVADQLLAKDKFG
IIEGE
>C8RWL3|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacter sp. SW2|TrEMBL
MTHALPSPAAPLKIGTRGSPLALWQAHETRRSLMAAFSLPEAAFEIVVIKVTGDQVQDRA
LKEIGGKGLFTREIEDALLDGSIDIAVHSMKDMPTLQPEGLLLDCYLPREDVRDAFVSPT
VARLADLPHGATVGSSSLRRRAQLAARRPDLNLVEFRGNVQTRMKKLEDGVAVATFLAMA
GLNRLGMAHVARSAIEVEEMLPAVAQGAIGIERRTADPRAEALLAGIHHGPTGIRLACER
AYLQELDGSCATPIAGMSVLEGDRIWLRGEILRPDGSEVIAGEIRAAASDAAEAGRDLAR
QLLGRAPEGFFSWR
>A3ISR5|hydroxymethylbilane synthase|EC 2.5.1.61|Cyanothece sp. CCY0110|TrEMBL
MVVSSRAIRIGSRKSQLALVQTYWIQEQLQKHYPDRQFDVETMSTQGDKILDVALAKIGD
KGLFTKELETAMLQNQVDFAVHSLKDLPTNLPDGLMLGCVTERVNPADALVVNEKHKDKQ
LDTLPEGSVIGTSSLRRLAQLRHHYPHLTFKDVRGNVNTRLSKLDAGEYDAIILAVAGLQ
RLDMSDRIHQVIPDDISLHAVGQGALGIECRTGDPEILDLLKALEHPETRDRCYAERAFL
RELEGGCQVPIGVNTKIENNFLTLTGMVASLDGKTLIKDTIEGEQDQAEKLGQELAMRLR
DAGATEILAAIFAEIQR
>F9N6C3|hydroxymethylbilane synthase|EC 2.5.1.61|Veillonella sp. oral taxon 780 str. F0422|TrEMBL
MRNIIRIGTRSSALALWQANYVADTLRKHYPQCKVELVHHSTKGDRILEKPLAEIGGKGL
FTEELEASMRDGSIDLAVHSLKDMPTELPEDLVLGAITERETPCDALVSPKYKTLDQLPQ
GAKVGTSSLRRQAQLLNQRPDLQISVLRGNVQTRLNKLETENFDAIVLAEAGLKRLGLES
VVTQTFTSDEMIPAVGQGALGIECRKDDTEMLDMLSVLHDENTMWATRGERSFLRQLEGG
CQVPMGVHGTIYKGQLTLKAIIASLDGKNCFEGELSGPKEKADMLGRNLAKALYEEGGKA
IIDDLVERGVLK
>G7A6R9|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-23A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>B8G818|hydroxymethylbilane synthase|EC 2.5.1.61|Chloroflexus aggregans (strain MD-66 / DSM 9485)|TrEMBL
MARLLLGTRGSALARTQSEWVANVLRNTFADLSVELRIITTTGDRVLDVALSAVGDKGLF
VKELEQALLAGDVDLCVHSAKDMPTATPPGLMLSAFPVREDPRDVLVVRHADVGTDLATL
PTGARIGTSSLRRASQLRYHRPDLHLNDVRGNVDTRLRKLASDQYDALILAAAGLRRLGL
WDGTPGASIGAALVYPLDPSVMLPAVAQGILAVETRTDDETTNRLVAALDDSAARTAALA
ERAFLRRLEGGCQIPVAAHAVLTEAGLHFRGMVGALDGSTLVFAEQVGDPAQPEAVGIAV
AEAVLAQGGEAILAAIRSQQEAQR
>H4BRK8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1057|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>A9KAC1|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei ATCC 10399|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>E6S4Y4|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain 35A)|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECFIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKERQGDKTKALDLVQELLEAFLQSGAKEIL
EKAQLF
>B6AWL8|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacteraceae bacterium HTCC2083|TrEMBL
MALAQAYETRRRLSGAFDLPEEAFVIKVIKTTGDKILDRPLKEIGGKGLFTREIEDDMLS
GAIDIAVHSMKDMPVLQPEGLVLDTYLPREDVRDAFVSSGHERLADLPSGAVVGTSSLRR
RAQLLNYRPDLNVVEFRGNVQTRLKKLEDKVADCTFLAMAGLRRLDMAHVAKSAIETEEM
LPAVAQGAIGIERRINDTNAAEMLAAIHDTQTGQRLAAERAFLAALDGSCETPIAGLAEL
DGSNMRFRGQVLRPDGSESIGDDVSGTIEDGVAMGEAMAAKLLAEAGEGFFEWRS
>F8EF49|hydroxymethylbilane synthase|EC 2.5.1.61|Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4)|TrEMBL
MHIKIGTRGSRLALWQAYYVENILQKGGLTTEIVLIDTKGDQILDRSLSKIGSKGVFTQE
LEDQLRDGRIDIAVHSAKDLQSELDDDLQLIAFTERERVNDVLVSHNQRLSLGSGETFVV
GTSSTRRVAMLKHFYPHIRTVDMRGNLQTRLRKLEEGQCDAILLAFAGVHRMEYDGLIAE
HLSLDEFTPAVGQGSVAIECSQQLDEEKRTQLRALLNHADTETCLLAERAFLRRLQGGCS
VPVFGLAGLENDTVTLKGGVVRLDGSQILKQTQSGPASAPENIGIQLAETLLSQGAAEIL
AAIKQNL
>F5SAG7|hydroxymethylbilane synthase|EC 2.5.1.61|Desmospora sp. 8437|TrEMBL
MVFPSSQSCPKGHWKRCEKVPQREGWVSHGVILYDRIRPALIHSAYRKPDGFHKEERIMR
TIVVGTRRSQLAVTQTQWVMEQVRDRLPQGWQMEMEKMVTRGDQILNVTLSKVGGKGLFV
KEIEQALLDGRIDFAVHSMKDMPGEMPEGLIFGAVTRREDPRDCLLSRKGEGLDDLPENA
CVGTSSLRRQAQLLAYRPDLRVEPVRGNLNTRYQKLMDGQFDAIILAQAGIARMDWTDKV
TQVVPEEVMLPAVGQGALAVQCRRDDQELLELLAEVNDPVTERAVTAERTFLQAFEGGCH
LPIAGRATVDGERIRLRGLVAHPSGTPILREEAEGADPVELGRRLARELMEKGARSLLEE
VKKGLEE
>C2CYI8|hydroxymethylbilane synthase|EC 2.5.1.61|Lactobacillus brevis subsp. gravesensis ATCC 27305|TrEMBL
MKPEFVVGTRQSKLAMRQTNLVVDALKERFPKIIFKVEKITTQGDRNRKDSLRKIGGKGI
FVKEIEQRLTDKRIDFAVHSLKDVMPSLPKNLIIGGVPKRDSPFDCLISTKPFSDIDQLP
KGARIGTSSSRRQGQFSHLRPDVEIVSIRGNVDSRIQKLQRDHLDGIILAEAGLNRLGVD
LTGLYRLSLKNDLLPAAGQGAIGIECRADDHDTLALLKQIEDADTRQSVTIERDFLRRLG
GSCNFPIGAFASQTSMGVRFDGLVASIDGKIFFSKSKTEQTGGNLGEEVADELISEGALT
LIQ
>A4YPB9|hydroxymethylbilane synthase|EC 2.5.1.61|Bradyrhizobium sp. (strain ORS278)|TrEMBL
MTRFRIGTRKSTMALAQTEEIARRLQAAIPSLDIEIVKFETTGDSDQTSKLLTHGGKGGA
FVAEIRRAMLDGKLHAAMHSLKDMPGNEETPGLVIAALLSRDPPGDVLVLRKGLALEDFR
KDGGRGFKIGTNAVRRAAYARRLFPHAELIHFRGAADTRIRKLDNGELQRMPDGGAVGPA
DALIMARSGLERVGLSDRASHEFPVADMLPAVGQGIVAVECPASDFETRRILATVDDAAA
RTCADAEREVLWVLNGHCNSPIAGFSTIDGAQMTLTASVLDEDGGRFIEAQRTGPADRPR
ELGRAVGLELLASGAAALIERSRPR
>H8FKD1|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas citri pv. mangiferaeindicae LMG 941|TrEMBL
MTTLRIATRKSPLALWQSEHVADALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDEPFVLPAILERGDPADALVSNLYASLQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEAR
ISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAAFARWEGQDLFLQGMVGSASDGRLIHADAHGSADDTEALGRRVAQGLFDKGAAQL
LAEL
>E6V2K3|hydroxymethylbilane synthase|EC 2.5.1.61|Variovorax paradoxus (strain EPS)|TrEMBL
MYFLGAVLSNIVIATRESRLALWQAEHVQALLQERGHTVSLLGMTTRGDQILDKSLSKVG
GKGLFVKELETAIEDGRADIAVHSLKDVPMDLPEGFVLACVLEREDPRDAMVSPRYASLD
ELPHGAVVGTSSLRRVVLLKARRPDVRIEPLRGNLDTRLRKLDEGQYDAIILAAAGLKRL
GLEDRIRVAFEPDDMLPAAGQGALGIEVRADREDLIELLAPLAHRGDWLSTAAERAVSRA
MGGSCSMPLAAHARWQADGVLRIDAAWGDPEGNAPLVRVHAQADVGDFGRADALGEHAAA
LLRDAGAH
>F0FF72|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK353|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKELHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPK
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRSLLAAVQDEKTAAEVAVERAVLAQM
NADCTFPIAAFAQKNGQNHQLEAMLAKEDGQCVFVSLQGQDGQELAEQAVRQLADKGAVG
MPWLKK
>H0U3G1|hydroxymethylbilane synthase|EC 2.5.1.61|Wolbachia pipientis wAlbB|TrEMBL
MLVKIGTRGSDLAIIQALETKQRLLESFPNLSVEIIKIKTSGDKYANVTLAEIGGKGLFL
REIEAELLKNNIDMAVHSLKDVPAFFSKDLTIPCVLERLSPCDVFISHKYKSLKTLPQQA
TIATSSIRRKVQLLNLRPDLNVVPLRGNVTTRLQNQNFDGMILAEAGLIRLKKYHLITEV
LPPKVMLSAVGQGAICIQCRKNDIKVIDLLEKINNNMSFIRAKSERSFMKTVNGSCFTPL
AALAEYVSENMLHLYCMLAGERVIYFTERTSFVEDAEKMGMDAGLELKSKCL
>H8J469|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium intracellulare MOTT-02|TrEMBL
MANVIRIGTRGSLLATTQAGVVRDALIALGHPAELVTITTAGDRSSGPIESLGVGVFTTA
LREAMEEGRVDAAVHSHKDLPTADDPRFAVAAIPVRNDPRDAVVARDGLVLGELPPGSLV
GTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTE
TLEPVQMLPAPAQGALAVECRAGDTRLAAVLAELDDADTRASVTAERTLLAELEAGCSAP
VGAIAEVVESIDEEGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFE
LGARELMRGARQDPTRGN
>H8J469|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium intracellulare MOTT-02|TrEMBL
MANVIRIGTRGSLLATTQAGVVRDALIALGHPAELVTITTAGDRSSGPIESLGVGVFTTA
LREAMEEGRVDAAVHSHKDLPTADDPRFAVAAIPVRNDPRDAVVARDGLVLGELPPGSLV
GTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTE
TLEPVQMLPAPAQGALAVECRAGDTRLAAVLAELDDADTRASVTAERTLLAELEAGCSAP
VGAIAEVVESIDEEGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFE
LGARELMRGARQDPTRGN
>C9RU60|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus sp. (strain Y412MC61)|TrEMBL
MRNIVVGSRRSKLALTQTKWVINELKQLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLF
VKEIEHELLAGGIDMAVHSMKDMPAVLPEGLVIGAVPRREDARDVLVSKGNRMLSDLPPG
SVIGTSSLRRSAQLLAYRPDLTIKWIRGNIDTRLAKLESEEYDAIVLAAAGLARMGWGDD
VISDYLPFDVCVPAVGQGALAVECREDDDELRQWLSRLNDEQTERAVRAERAFLQQMEGG
CQVPIAGYAEADGGMVRLTALVASPDGKEKYKEMVTGADPEAVGRQAAAVLIEQGAKALI
ERVKQELSQS
>H2HZQ7|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain PW8)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>F6CIX9|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfotomaculum kuznetsovii (strain DSM 6115 / VKM B-1805 / 17)|TrEMBL
MKQEIIIGTRDSQLAMWQARWVLEKLQKLYPRKRFVLRGMKTRGDHILDVALAKIGDKGL
FTKELELALSAREIDLAVHSMKDLPTRLPEGLIIGAFCQREYPGDVLISRYGHTLETLPP
GARIGTSSLRRTAQLLHFRPDFNVTTIRGNLTTRLRKLEELNLDAIILAYAGIHRLGYDA
RITQLIPFDICLPAVGQGAIAIEIRANDPEMQELIRPLDDPASRTAITAERALMRKLEGG
CQVPIGALGQIQHEQLLLEGAVASFDGCQLVRDSISGPPNQAEKLGEELAVRLIKLGAGE
ILKKARQEFDLE
>G0GSQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Klebsiella pneumoniae|TrEMBL
MLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLKVELVPMVTRGDVILDTPLAKVGGKG
LFVKELELAMLEGRADIAVHSMKDVPVEFPEGLGLVTICERDDPRDAFVSNRYASIDELP
AGSVVGTSSLRRQCQLAATRPDLAIRSLRGNVGTRLSKLDNGEYDAIILAAAGLKRLQLE
ARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTRGLLAPLNHTETAVRVRAERAMNTRLEG
GCQVPIGSYAELKDGELWLRALVGAPDGSQLVRGERRGPAEQAEALGISLAEELLDNGAR
EILAAVYDGEAPR
>F9UXA5|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium bovis BCG str. Moreau RDJ|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>F9UXA5|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium bovis BCG str. Moreau RDJ|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>D2TV25|hydroxymethylbilane synthase|EC 2.5.1.61|Citrobacter rodentium (strain ICC168)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMANHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLEKRADIAVHSMKDVPVEFPAGLGLVTICEREDPRDAFVSNNYPSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEVSLPAVGQGAVGIECRLDDRRTQALLAPLNDEITALRVKAERAMNTRLEG
GCQVPIGSYAEMIDGELWLRALVGAPDGSLMVRGERRGSPEQAEQMGISLAEELLDNGAR
AILTEVYNGESPA
>F7WQT5|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis (strain CCDC5180)|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>F8EU92|hydroxymethylbilane synthase|EC 2.5.1.61|Zymomonas mobilis subsp. pomaceae (strain ATCC 29192 / JCM 10191 / NBRC 13757 / NCIMB 11200 / NRRL B-4491)|TrEMBL
MQFPFRLGSRGSPLALIQARIVATALCSAHGWSEEAVIIVPIRTSGDKNRHQALADIGGK
SLWTKELDTALTAGEIDAAVHSMKDVETFRPDHISIAAMLARADVHDRLIGAPSLETLPL
GACVGTASPRRAAQIRHRRSDIQIKLLRGNVATRLQKLEDKAFDATLLAAAGLIRLGKGD
IGYTIPLSEMLPAAGQGAIGIEALANSAAWSIIAAIDHQPTHRAVDTERQLLMRLNADCH
SPIAAFAEVKENGIRLRACLYTADGQLSTAIDKFILQPSDAFDVGTLLLNQAPPELKSLF
KVDVSFTG
>E3DD17|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia sp. (strain Ejp617)|TrEMBL
MSDKILRIATRKSPLALWQAKYVQQRLIDCHPGLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEQAMLSGSADIAVHSMKDVPVAFPQGLGLVAICERDDPHDAFVSNRHASVDSLP
QGAIVGTSSLRRQCQLSARRPDLVIHSLRGNVGTRLGKLDAGEYDAIILAVAGLKRLGLS
DRIRQVMPAEESLPAVGQGAVGIECRLDDMHTIGLLAALNHDETACRVSAERAMNTRLEG
GCQVPIGSYALLEGDQLWLRGLVGSPDGSQMVRGERRGSRADAEKMGISLAEELLDNGAR
DILAAVYQGNPPA
>I2AJN3|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium sp. MOTT36Y|TrEMBL
MIRIGTRGSLLATTQAGVVRDALIALGHPAELVTITTAGDRSSGPIESLGVGVFTTALRE
AMEEGRVDAAVHSHKDLPTADDPRFAVAAIPVRNDPRDAVVARDGLVLGELPPGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRADDTRLAAVLAELDDADTRASVTAERTLLAELEAGCSAPVGA
IAEVVESIDEEGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFELGA
RELMRGARQDPTRGN
>I2AJN3|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium sp. MOTT36Y|TrEMBL
MIRIGTRGSLLATTQAGVVRDALIALGHPAELVTITTAGDRSSGPIESLGVGVFTTALRE
AMEEGRVDAAVHSHKDLPTADDPRFAVAAIPVRNDPRDAVVARDGLVLGELPPGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRADDTRLAAVLAELDDADTRASVTAERTLLAELEAGCSAPVGA
IAEVVESIDEEGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFELGA
RELMRGARQDPTRGN
>D5VDP3|hydroxymethylbilane synthase|EC 2.5.1.61|Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 / TK0059)|TrEMBL
MNFASAGNVPTVSRQPPIRIGARGSKLSLAQSGLMQARIAAALGAPAGASKEEIEAFAPL
IPIVTSGDRIQDRRLMEIGGKGLFTKEIEEALLDGRIDCAVHSLKDMPAELPPGLVLAAT
PEREDPRDAFISHVCERLEDLPKGARLGTASLRRQAQALHVRPDLEIVMLRGNVDTRLAK
LERGEADAILLAQSGLNRLGLGHLTKSWIDPDACPPAPGQGALVIETRAEDIGAAWLDAV
RCRPTTIAVAAERGALLALEGSCRTAIGARATLDGARLSMIVEALTPNGAQRFRRHGEIT
LSGGDDAGEALALGLKLGAEVRAEGGDAILLPE
>C3MAF1|hydroxymethylbilane synthase|EC 2.5.1.61|Rhizobium sp. (strain NGR234)|TrEMBL
MQTKPFRIGTRGSPLALAQTHETRDRLAAAHGLPPEMFEVVVLSTKGDRITDRPLAEIGG
KGLFTEELEQQLLSGDLDFAVHSSKDMPTKLPDGLFLSAFLPREDIRDAFVGRTAPRLVE
LPEGATVGSSSLRRQALIRRLRPDINVITYRGQVETRLRKLAEGQVDGTLLAFAGLKRLG
MTDVPTELLDPKEFPPAPAQGAICIESRDGDDRVNALLAAIDDPRTHEAVACERGFLATL
DGSCRTPIAGYAQSDGTYIRFSGMILTPDGATSHRVEIDGKAQDATELGRKAGEQIRDKA
GPGFFSSWT
>E2CDR2|hydroxymethylbilane synthase|EC 2.5.1.61|Roseibium sp. TrichSKD4|TrEMBL
MQSTLLRIGTRGSQLALAQAHETRDRLMAAHGLPEDAFEIVVVKTSGDQIQDRPLSEVGG
KGLFTKEIEDMLLDGSLDLAVHSSKDMPTVLPAGLDITAFLPREDVRDAFISPKAKTLRD
LPHGAVVGSSSLRRQAMVKRLRPDIDVVMYRGNVQTRLRKLDEGVVDATLLAHAGLKRLG
LGDVVTSVIEADDFVPAVGQGAICLESRLDDEKTNGLLSAINDPETRVRLEAERAFLGVL
DGTCRTPIGGLATVDGDTLTLKGVILKPDGSQMHEVEHSGSVQDAEAIGLAAGEELKSKA
GPNFLTS
>H7ZG73|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 2008-1025|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>Q2Y5J4|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849)|TrEMBL
MPNSSTPNKIVIATRESALALWQANFIRDRLAELYPQMEFQISGMTTRGDQILDVTLSKI
GGKGLFIKELEQALEDGRADIAVHSMKDVPMDMPAGFALAAITEREDPRDAFVSNKYARL
DALPPGSVVGTSSLRRESQLRARFPHLQVQPLRGNVQTRLRKLDEGQFAAIILAAAGLKR
LGLAERITALLSPDLSLPAVGQGALGIECRADRSDLIKLMEPLHHIPTARCVEAERAMSR
ALGGSCEVPLGGFAEIDGHVLRLRGFVASQDGIRMVSDELNGSPDDCASIGAQLAKNLKA
KGAEEILVALESKAVDPVSHP
>F8YUN3|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-40A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>Q2C2Q7|hydroxymethylbilane synthase|EC 2.5.1.61|Photobacterium sp. SKA34|TrEMBL
MSNQLIRIATRKSPLAMWQAEFVKAEIEQAHPGISVELVPMITKGDIILDTPLAKVGGKG
LFVKELEVAMLEGRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNKYNNIDELP
QGAIVGTSSLRRQCQLRAQRPDLIVNDLRGNVNTRLRKMDEGQYDAIILACAGLKRLKME
DRIRSEIAPEVSLPAVGQGAVGIECRLDDTRVRQLLTALSDQATTTRVLCERAMNNHLQG
GCQVPIGSYAELEGDQVWLRALVGEPDGSKIVRAEIRGPIEQAEQLGETLAEQLLNDGAR
DILDRLYGNA
>D7BDK2|hydroxymethylbilane synthase|EC 2.5.1.61|Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2)|TrEMBL
MSRVRIATRGSRLARWQAEWVAAQLQDQGIASTLVIVETQGDRERVAFSQMQGQGFFTKA
VQDAVREGRADLAVHSLKDLPSAPTPGLVLAAIPIREDPREALLVLPSAWDAQAPALPLA
PGARVGSSAVRRQAQLAQLRPDLKLLELRGNVPTRVEKLQSGGYEAILLAWAGLKRLGLD
LGGLAVRLLEPREFVPAPGQGALALECREEDTQLRGVLQGLDDPTARLTVGIERGLMARL
QGGCQLALGASAQRVQGGWQLLAWYGGRRYEALGAEPQDVIEGIYAQILADHPEAIGAMG
EVRR
>E8W3G9|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)|TrEMBL
MSAPELIRIVSRDSPMALAQVERVRAGLAALHPDTVTEVVPVRTTGDKWLGDLSKVEGKG
AFTKEVDAALLAGEADLAVHCVKDIPADRPLPAGTTFAAFLERDDIRDALVHPDGLTLEQ
LPEGTRIGTSSVRRTAQLASSHPHLDCVPFRGNANRRLAKLAAGEADALLLAVAGLHRIG
RPDVISDILAPETMCPPIGAGVLALQCREDDTATIEAVGALNHPGTYREITAERMFLHVL
QGHCNSPIAGYATAHRNGDLSLRACVFTPDGKTVLNAHEWAGPLDPATLGTSVAVSLLRQ
GARELIDSIAH
>E7U0J6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli WV_060327|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDN
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>H7QXT0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 90-3|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>D8HBX9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus (strain ED133)|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>Q10VY0|hydroxymethylbilane synthase|EC 2.5.1.61|Trichodesmium erythraeum (strain IMS101)|TrEMBL
MTISASTPTIRIGSRKSQLALIQTYWVQEKLEKNFPNITFEVHKMSTQGDKILDVALAKI
GDKGLFTKELELGMLQNETDLAVHSLKDLPTNLPEGLILGCVTERENPADALVLHEKLKD
KQLETLPEGAVIGTSSLRRLAQLRYHFPHLEFKDVRGNLNTRLAKLDAGEYDALILAFAG
LHRLGMSDRIHQIIPPEISLHAVGQGALGIECRAGDNNILNLLKSLEHTATAQRCYAERA
FLRELEGGCQVPIGVNTQIEGEQLTLTGLVASLDGKKLVKDIVTGATADAEQIGIELAQK
LRKQGAQEILDQILAEINRS
>H7TLG6|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 1891|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>H3Z3D5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU081|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>F3UCD0|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK1056|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKAIHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLANLPE
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRSLLATVQDEKTAAEVAVERAVLAQM
NADCTFPIAAFAQKNGQNYQLEAMLAKEDGQCVFVSLQGQDGQQLAEQAVRQLADKGAVG
MPWLKK
>G7AT31|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-32A1|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>C5Q3J1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus TCH130|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>B9L8M3|hydroxymethylbilane synthase|EC 2.5.1.61|Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH)|TrEMBL
MKLTIATRGSKLALWQAEWVKSKLEKLGHEIDLKIVTTTGDKILDKPLAEIGGKGLFIKE
VEEALLKGDAQIAVHSLKDFPTQYETDHFTLAAIPVREAVEDVFLSENFETLAELPHNAV
VGTSSIRRAMQLKAFRDDLVITDLRGNVDTRINKLKDGKYDAIILAHAGVKRLGLLKSVK
YFEVLDTDIMIPAMGQGALGIETINDPKVIEAVKPLNDFRTQICVTIERDFVDTLNLGCH
APVGVYAKIMADDSIKIKAALLKDDKMIKKEVVISFDEWENAGKEFAKEFM
>A7C2T8|hydroxymethylbilane synthase|EC 2.5.1.61|Beggiatoa sp. PS|TrEMBL
MINKNIIRIATRKSPLALWQTHHVRDILCHAHPQLQIELVEMTTQGDKILDVPLAKIGGK
GLFVKELENGLFEGKVDIAVHSMKDVPVEFPPGLILPVIMEREEPYDAFVSNHYSGFTAL
PQGAIVGTSSLRRQCQLLVLRPDLQIRTLRGNVGTRLKKLDNGDYDAIILAAAGLKRLGM
AERIREVLKPEVMLPAIGQGAIGIECRADDTETQQLIAVLNHKPTQERLKAERALNEQLN
GGCQVPIAGYAEIEAEMMTVRGLVGDIDGKEVLHHKVQGPIESAETLGKELATELLAQGA
DRLLAKLIE
>C4LLC1|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717)|TrEMBL
MIRIGTRGSALALTQAGHVRDALISAGLEAELFTVHTPGDASQGAGTPVARIGVGVFTQT
LRTALAAGECSLAVHSFKDLPTAPDPRFRLAVPPRVDARDVVFSRDRIPLADLPAGSMIG
TGAPRRMGQVRALRPDCTVVPIRGNVDTRIGRLEKDLDAVILARAGVERLGRLAEATETL
DVDTVLPAPAQGALAVEAVAEGHENCSEEALYAIHVLDHEMSHRRAIAERAVLASLNAGC
TAPVGAYATEDSFRAGVFAVDGSERVTWSSEGEPTEDIGHQAAEYLRAHNAMDLM
>C4LDV4|hydroxymethylbilane synthase|EC 2.5.1.61|Tolumonas auensis (strain DSM 9187 / TA4)|TrEMBL
MTELRIATRKSPLALWQANFVKQQLELHHPGLQVTLVPMSTQGDKILDTPLAKIGGKGLF
VKELEQAMLENRADIAVHSMKDVPVDFPDGLGLAVICERDDPYDAFVSSRFASVYELPEG
AVVGTSSLRRQCQLRAQRPDLVIRDLRGNVNTRLAKLDAGDYDAIILAAAGLRRLDKAER
IRSRLPPELSLPANGQGAVGIECRLGDTQTLALLASLEHATTRYCVMAERAMNRTLQGGC
QVPIGAFAEMQDNDHLWLRGLVGSVDGKQIIHGDISGPKEQAEELGKLLAEQLLVQGADD
ILRAVYGA
>D0Z991|hydroxymethylbilane synthase|EC 2.5.1.61|Edwardsiella tarda (strain EIB202)|TrEMBL
MQSMTTATQPTLRIATRQSPLALWQAHYVRDQLLTHWPQLTIELVPMVTRGDVLLDTPLA
KVGGKGLFVKELELALLEGRADIAVHSMKDVPVAFPDGLGLVTICQREDPRDAFVSPRFA
SLEQLPPGSVVGTSSLRRQCQLRAARPDLQIRDLRGNVGTRLAKLDAGDYDAIILAAAGL
KRLQLDDRIRTPLTPEQSLPAVGQGAVGIECRLADDATRRLLAPLNHADTALRVCAERAM
NTRLEGGCQVPIGSYAEIDGDQLWLRALVGAPDGSRIIRGERRGPLTQAEAMGTALADEL
LARGARTILDAVYCQKA
>H1WFV2|hydroxymethylbilane synthase|EC 2.5.1.61|Arthrospira sp. PCC 8005|TrEMBL
MTTSVSAQTRTIRIASRKSQLALVQTYWVQEELQKRFPDIKFEVHTMSTQGDKILDVALA
KIGDKGLFTKELEVGMLNHDTDMAVHSLKDLPTNLPEGLMLGCVTEREDPADALVVHENH
RDKQLDTLPPGAVVGTSSLRRLAQLRHNFPHLEFKDIRGNLNTRLQKLDEGQYDAIILAV
AGLKRLGMADRIHQVIPAEISLHAVGQGALGLECREGDTEIFEVVKALEHTVTAQRCHSE
RAFLRELEGGCQVPIGVNTMVEGDRLTLTGMVASLDGKRLIKDTVTGQASDAEQLGIQLA
HKLKQQGAEEILAEIFAEVQRS
>F1DBF3|hydroxymethylbilane synthase|EC 2.5.1.61|Homo sapiens|TrEMBL
PTAHCASSWLHHRSHLQAGKPS
>H7TD37|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 7--1|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>B0AUZ3|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus anthracis str. A0488|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>E8GBJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008284|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H8CYC4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 23210|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>H8GTV9|hydroxymethylbilane synthase|EC 2.5.1.61|Deinococcus gobiensis (strain DSM 21396 / JCM 16679 / CGMCC 1.7299 / I-0)|TrEMBL
MRTVTVGTRGSALALAQTRWVVARLKEEWPETDFRIQTISTKGDRSRESLGTMAQKGDKG
FWVKEIEDALLQKQVDIAVHSLKDLPTAQPEGLEVSAIPKRVDARDVLIGREGMKKLADL
PAGARIGTSSVRRKAFLRAYRPDLVVKDLRGNIDTRLAAIGGGEYDAIILAAAGLIRTEQ
RHRIDEFVATDILLPAPGQGALALETRADDDLSIEVAYAIHDHMTDDRITAEREFLAGLG
AGCMAPVGAHATVKGGVLTLEGWVGGIDGRKVIRAESSGDATECADLGAELAADMLAQGA
QELIDAAHG
>E7RW43|hydroxymethylbilane synthase|EC 2.5.1.61|Lautropia mirabilis ATCC 51599|TrEMBL
MTESAYSAPLRIATRESRLALWQANHVAELLRARHPAAGVALLGMTTRGDQILDRPLAEI
GGKGLFTKELEVALFDGRAELAVHSLKDVPMDLPEGFDLAAVMTRADARDAFVSTRYASL
DELPPDAVVGTSSLRRAAQLQARHPGFRIQPLRGNLDTRLGKLDAGQYDAIVLAAAGLTR
LGLADRIRQYLPLDEMLPAPGQGMLGIEIRADRDDVRQALAFLNDPEAARIAAAERAVSR
QLGGNCKTPLAAHARFTASGQMQLDALLADDDGRIARVTRVGKVADPKEARVMGEAVAAE
LKAQLAAAPKPSGQS
>I5HPX7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA14|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H5VFY8|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Senftenberg str. SS209|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHS
LDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELL
ENGARAILTEVYNGETPA
>H7SGQ1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 80352|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>A5EDX9|hydroxymethylbilane synthase|EC 2.5.1.61|Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)|TrEMBL
MTRFRIGTRKSTMALAQTEEIARRLQAAIPSLDIEIVKFETTGDSDQTSKLLTHGGKGGA
FVAEIRRAMLDGRLHAAMHSLKDMPGNEETPGLVIAALLSRDPPGDVLVLRRGLSLDEFR
KDGGRGFKIGTNAVRRAAYARRLFPQAELIHFRGAADTRIRKLDNGELQRLPDGGAVGPA
DALIMARSGLERVGLSDRASFDFAAADMLPAVGQGIVAVECPSLDWETRRILATIDDGAA
RSCADAEREVLWVLNGHCNSPIAGFATIDGDQMTLTASVLDEDGGRFIEAQRAGPADRPR
ELGRTVGLELLANGAAELIERSRPR
>I5RMR7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW10119|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D3UND9|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954)|TrEMBL
MKRKIIVGSRRSKLALTQSGWVIARLKENYPEIDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDGAIDFAVHSMKDVPSSIKEGLTIGAIPKRESALDCFVFNTVESFHDLPT
AAVIGTSSLRRAAQILRQRPDFVIKPIRGNIDTRLQKLHDENFDAIILAKAGLSRMGWLE
NTTLKLEDISPELCLPAVGQGALAIECRENDKQICDMLASIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATKTAGQIKFKGLVGNADGSTILSAERTGENPMTIGNQVAEALLSEGAD
TIIKELRNS
>E7JZ00|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella sonnei 53G|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAKQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E8E0T7|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 2009083312|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>C9RPT6|hydroxymethylbilane synthase|EC 2.5.1.61|Fibrobacter succinogenes (strain ATCC 19169 / S85)|TrEMBL
MSDLKLRIATRKSALALAQTTMAADAIVAANSVIGNAADSNNARDSLTYELVSMTTEGDR
RLDKSLASFGGKGVFIKELEIALLEGRADIAIHSLKDMPAEVLPQFKLAAVLKREDPRDA
FLSRGGSAGIRFMDLPAGARVGTGSIRRVVQLKALRPDLEYVPIRGNIQTRIGKLAELDG
VVLAAAGLKRMGLADQVTEYFSTEQMLPASGQGILAIETLNDATVQESRVTGRADLAQIL
ARVNDVATYCIASAEMAYLKALNAGCQFPVASFAEFVCEDGIENRGTCGALEENANRIAQ
TLKIRGIYWDEKSEKLLRAEVAGNVDLNSEDCVQQSKNLGIELACAIQKQL
>Q5P7H6|hydroxymethylbilane synthase|EC 2.5.1.61|Aromatoleum aromaticum (strain EbN1)|TrEMBL
MSATPDFPAPERLVIATRESRLALWQAEHVKARLEALYPGCRVELLGMTTRGDQILDRPL
AKVGGKGLFVKELEAALLEERADIAVHSMKDVPMQLAEPFALPCISAREVPLDAFVSPRY
ASLADMPPGTVVGTSSLRRESQLHAQFPFLAVTSLRGNLDTRLRKLDEGQYDAIILAAAG
LRRLGLADRIRAELPSEVSLPAAGQGALGIECLAKRTDIAAWLAPLNDADTSACVRAERA
VARALAGSCEVPLGAYAEIRAGRLWLRGFVALPDGSRMVRAEREGDAADAEGLGLALADD
LRAQGAEDILARLG
>H1TMM8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21333|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>I5EP98|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli FRIK1985|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F0RP44|hydroxymethylbilane synthase|EC 2.5.1.61|Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM Ac-1939 / CCM 2703)|TrEMBL
MRTVTVGTRGSTLALSQTRWVVERLKEQWPETEFRIQTITTKGDKNRASLQSMAKAGDKG
FWIKEIQDALLAKSIDIAVHSLKDLPTEQTEGLDIASIPKRADARDVLVGAEGFKSLADL
PQGARIGTSSVRRRAFLKAFRPDLQVIPVRGNIETRMAAVASDDYDAVILAGAGLIRTDQ
RHRADEFVSTDILLPAPGQGALALEVRADDDLIAEVAYAINDAVTDDRITAEREFLAGLG
AGCLAPVGAFATVKGDLLTLEGWVGAVDGSEVIKATTSGDASECADLGAELAEDMLSQGA
QRLIEMAKED
>H4V867|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC6B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H5N1C2|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC14A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I5HT69|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA15|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H4IIL4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC1B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H4EGG1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1612|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H7TZA4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 59-2|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>G9U160|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. LQC 10|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>C9QBU2|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio orientalis CIP 102891 = ATCC 33934|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALKAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYHNIDEL
PQGAIVGTCSLRRQCQLKEYRPDLVIKELRGNVGTRLGKLDDGQYDAIILAAAGLKRLEL
EERIKSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHKETADRVLCERAMNLTLE
GGCQVPIGSYSLIDGDNIWLRALVGEPDGSKIIRGEIRGSRADAETLGVELANQLLDDGA
KEILTKLYAEHE
>H4WI32|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC6E|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I0RY95|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium phlei RIVM601174|TrEMBL
MSVIRIGTRGSLLATTQAGTVRDALIARGHEAELVIVSTEGDRNQGPIVDIGVGVFTAAL
REAIAAGEVDCAVHSHKDLPTAGDPRLQLPAIPPREDPRDVLVARDGLVLGELPAGSVIG
TSSPRRAAQLKALGLGLEIRPLRGNLDTRLSRVSNGELDGIVVARAGLARIGRLAEATET
LEPVQMLPAPAQGALAVECRADDTELAALLAELDDADTRAAVTAERALLARLEAGCSAPV
GAIAEVVESIDEDGNVFEEVSLRACVAALDGSDVIRASGVGTPDRARELGFSVAEELFEL
GARELMADAT
>I0RY95|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium phlei RIVM601174|TrEMBL
MSVIRIGTRGSLLATTQAGTVRDALIARGHEAELVIVSTEGDRNQGPIVDIGVGVFTAAL
REAIAAGEVDCAVHSHKDLPTAGDPRLQLPAIPPREDPRDVLVARDGLVLGELPAGSVIG
TSSPRRAAQLKALGLGLEIRPLRGNLDTRLSRVSNGELDGIVVARAGLARIGRLAEATET
LEPVQMLPAPAQGALAVECRADDTELAALLAELDDADTRAAVTAERALLARLEAGCSAPV
GAIAEVVESIDEDGNVFEEVSLRACVAALDGSDVIRASGVGTPDRARELGFSVAEELFEL
GARELMADAT
>H7T2D5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 1148|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>B5V6K5|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus H3081.97|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKEKVVGTDPEKVGLEAADRLINQGAKEL
ILAANKEQQ
>D4H6I4|hydroxymethylbilane synthase|EC 2.5.1.61|Denitrovibrio acetiphilus (strain DSM 12809 / N2460)|TrEMBL
MEKVVIATRGSNLALWQAYYTRDRLQKEHGVEVELNIIKTKGDKILDVPLAKIGGKGLFV
KEIEQALIDGKADIAVHSMKDVPMEMPEGLELYASPEGASPYDCFVSVKYNEVVELPQGA
VVGTSSLRRKLQLLKMRPDLVIKDLRGNVNTRLAKLEAGEFDGIVLAKAGLVRLELGHVI
KETFTADQMLPACCQGALGFQIRANDTRMKELLRFMKDPATETKVSMERAFLRRLEGGCQ
APIAGHSVLTGSKICMKGIVAALDGRTFIEQFIEGHAEDAEKLGLELAERVLNAGAKDIL
EEIYSQAD
>B3YF58|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Kentucky str. CVM29188|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDVLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>F6DBI6|hydroxymethylbilane synthase|EC 2.5.1.61|Thioalkalimicrobium cyclicum (strain DSM 14477 / JCM 11371 / ALM1)|TrEMBL
MKNHLRIATRKSPLALWQAEFVKAELEKAHAGLKVTLVPMSTRGDKILDVPLAKVGGKGL
FTKELEEQMLAGQADLAVHSMKDVPMVLPEGFALSAIMARHDPSDAFVSNNYANLDELPQ
GAILGTSSLRRQAQFQALRPDLEIRFLRGNVGTRLGKLDAGEYDAIVLATSGLERLGLDE
RIRCKMQPEQILPAVAQGALGIETLANDTETQALIAVLNDPLTATVVKAERAMNRCLDGG
CQVPIGGFALLENDQVWLRGLVAEPDGSKMIKMEGRAPASQAEGLGRLIGQALLDAGAKE
ILAKLYQPESA
>D9QJX2|hydroxymethylbilane synthase|EC 2.5.1.61|Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81)|TrEMBL
MATIRIGTRRSALALAQSGMMQRAIAAAMQLPIEEVVLVEIVTTGDQIQDRRLMEVGGKA
LFTKEIEEALLDGRVDIAVHSMKDVPAEQPPGLTIAAIPEREDARDAFISRDFDELEHLP
HGGRLGTASLRRQAQALALRPDLQIEMLRGNIDTRLRRAAEGDFDAILLAASGLNRLGRS
DAVRGFLSVDAFLPAPGQGALALQTREGDTDHAWVQAMNHGPTALCVAAERGAMVALEGS
CRTAVGAHAHIDGDRLTLTTEMLAPDGTARWRRAGEITLITAPDAPGRAMDNARDLGLRL
GHEVHAAAGDQSVPV
>E6W4I3|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfurispirillum indicum (strain ATCC BAA-1389 / S5)|TrEMBL
MKIVIGTRASQLALWQAEHIKAELESRWDDVQVELKKIITKGDKILDSPLAKVGGKGLFV
KEIENELIDGTIDIAVHSMKDVPTEFPEGLELFAITEREDPRDAFISRNGKSMAELGQQK
DVTIGTSSLRRQAQLLTLYPHWNIVSIRGNVQTRLKRMEERQMDGIILAAAGMKRLELEH
LVKEYIAPEVMIPAIGQGALGLEVRSADTALKERLEFLRHPVTTQCVLAERALLRTMEGG
CQVPIGAYAVPKENGSVFLNALVASVDGKEVVKGQLEGNNPEELGVTLANQMLNSGARAI
LSVVYHNN
>G2D8Z5|hydroxymethylbilane synthase|EC 2.5.1.61|endosymbiont of Riftia pachyptila (vent Ph05)|TrEMBL
MAQHGAPSVTACGLRWGRRRREYESCKAHLLMSDNRIRIATRKSPLAMWQAEHVAAELKR
AHPGLEVELLGMSTQGDKILDTPLAKIGGKGLFVKELEQAMLEGRADIAVHSMKDVPAEL
PEGLHLPVIMQREDPRDAFVSNQYSSFESLPEGARVGTSSLRRQCQLAEARPDLQIKPLR
GNVNTRLRKLDEGEYDAIILASAGLKRLGFEQRITAFIAPEQSLPAIGQGAIGIECRSDD
AQVNALIAPLHHVDTAACVHAERAMNNRLMGGCQVPIAGYAMLEAGNLWLRGLVGEIDGS
QILRGEAEGTPDEAESLGVGLAERLLEWGADEILSTLYAD
>B2P8E4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC4113|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>G2FVW3|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfosporosinus sp. OT|TrEMBL
MKNNIRIGTRDSQLAMWQAEWVQSQLTMFYPQLKFELVPMKTKGDKILDVPLSRIGDKGL
FTKELEHGLINNELDMAVHSLKDMPTLLPTGLMISAYCEREEPRDVYLSKSGIRLEELPS
GSIIGTSSLRRKSQLKHYRPDLNFMDLRGNLQTRWKKLLESDMEGIVLAAAGVKRLGWEE
RITQILSEDMMLSAVGQGSIAIEIGENRSDIHELLSHLNHSDTEQAVCAERALMRKLEGG
CQVPIGALAQVMEGQIILRGMVASLDGERLIKAEAKGVDPDEVGHDAAGRLIALGANDIL
AEIR
>Q2NEP4|hydroxymethylbilane synthase|EC 2.5.1.61|Methanosphaera stadtmanae (strain DSM 3091)|TrEMBL
MIVGTRGSKLATTQTKTVVKALEEITGEEIETKIIKTTGDKIKNSQLYNIDAKGIFTKEL
DTALIDGSIDFAVHSFKDLPSELNDQLTITAIPQREAINEVLISNYSWDELPENATLGTS
SVRREAFCKLHGKKIQTKPIRGNIDTRIRKVEEGEYDATIMALAGINRLGLQEHIKEVFD
EQYITPPAGQGALAVMTHKDSEYNDVISKLNHEDSRIEAMTEKAILETIGVGCQWPIGIV
SKVDGNNINIHCKLLSPEGKLLADVNKTTDKNNAINTAKVIGTKLREDTL
>F0QSZ1|hydroxymethylbilane synthase|EC 2.5.1.61|Vulcanisaeta moutnovskia (strain 768-28)|TrEMBL
MKIRIATRGSRLSLIQSDIVMRMLRRVEPNIQFEVIIIRTTGDLVQDKPLYAIGTKGIFE
KEVNLALLKDEADIAVHSLKDLPSEISPGLVIAGFSPRDPPFDVLVVRNDYPSDLMALPS
GAKVGTSSVRRRAFLLSVRKDISINVIRGNVDTRINKLIRGDYDAVVIAEAGLVRLINDM
KSLHIRYARIPLDLLPPAPGQGIIAVVTREKDTNLIDLLRKASDPKAMVEALAERAFLRT
VGGGCHVPVGGIAIYDGNYMEFIAGIADINGNRKVIVKIRDSSIDPERLGINAAHELLRQ
WNERT
>C7NUU7|hydroxymethylbilane synthase|EC 2.5.1.61|Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2)|TrEMBL
MSSRATTFRLATRGSDLALRQTGAIRDALESRRHEVELLEVETTGDELRDELIHRLGKTG
AFVHSLDERVRAGEADAAVHSLKDVPTEDREGLTVAAVPERAPANDVLVTPDGTDLDDLP
EGATVGTSSLRRRAQLLAERPDLDVQPLRGNVDTRVEKLLAPTLKAEYTARLDAQESEET
TENGDDETKATGQTFEQSFDDWFNGLAEIERKATAREVDTEYDAIVLAEAGLDRLGLTHH
LDFQALPDEQFVPSPGQGVVAVVAEEGEAAEAIRDIIDDARTRVEATVERTILETLGGGC
VAPIGVRAVFQGRVVTTTVRVLAPDGTEEIADRRALPVEDHVDAARELGEDLADRGADEV
IERAKEMAEADDT
>E7VG73|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 315996572|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>A3YIR9|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni CF93-6|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>I0ZFY7|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori P79|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEKSAFCCRLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKQGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>G9VJV6|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 4441 H|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H0K6M1|hydroxymethylbilane synthase|EC 2.5.1.61|Saccharomonospora azurea SZMC 14600|TrEMBL
MTDRTLRIGTRGSRLAMSQTGTVAALLEKAGWKVELVPVATPGDQSSAPIAEIGVGVFTS
ALRQALLDGEVDIAVHSYKDLPTAPQPGIALAAVSEREDPRDALVARDGLTLGELPPGST
VGTGSPRRMTQLRALGLGLNVVPIRGNIDRRLAMVESGELDAIVLARAGLARTERVGLIT
ETLDPLQMVPAPAQGALAVETRVDDVDMEHLIHSVVDHEPTRVAVTAERALLARLEAGCS
APVGALADVVEDVDSEGAVIERVSMRGVAATAVEGDSVRILRASAVAEKSEAEQLGFRLA
DELLDLGAGALAR
>H0K6M1|hydroxymethylbilane synthase|EC 2.5.1.61|Saccharomonospora azurea SZMC 14600|TrEMBL
MTDRTLRIGTRGSRLAMSQTGTVAALLEKAGWKVELVPVATPGDQSSAPIAEIGVGVFTS
ALRQALLDGEVDIAVHSYKDLPTAPQPGIALAAVSEREDPRDALVARDGLTLGELPPGST
VGTGSPRRMTQLRALGLGLNVVPIRGNIDRRLAMVESGELDAIVLARAGLARTERVGLIT
ETLDPLQMVPAPAQGALAVETRVDDVDMEHLIHSVVDHEPTRVAVTAERALLARLEAGCS
APVGALADVVEDVDSEGAVIERVSMRGVAATAVEGDSVRILRASAVAEKSEAEQLGFRLA
DELLDLGAGALAR
>E1W2L5|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus parainfluenzae (strain T3T1)|TrEMBL
MAALKTLKIATRQSPLALWQANFVKDQLEKFHPTLSVELVPMVTKGDVILDSPLAKIGGK
GLFVKELENALLEKRADIAVHSMKDVPMEFPEGLGLSVICKREDPRDAFVSNTYRSLDEL
PQGAIVGTSSLRRQCQLKQLRPDLDIRSLRGNVGTRLSKLDNSEYDAIILASAGLIRLGL
AERIASFIEVEQSLPAAGQGAVGIECRVDDEEVKALLAPLSDATTTTCVLAERAMNTRLQ
GGCQVPIGGYAIEQNGEIFLRALVGEADGSAIIRAEGKSAVENAEALGVTIAEQLLAQGA
DKILTKIYSA
>H4NG09|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC3D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E2MRX3|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella novicida FTG|TrEMBL
MKQITIASRESKLALWQTNFVKNRIQSELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEIAMLNNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
IVGTSSLRRKAQLLHYRDDLEIRDLRGNVQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>E3GWS3|hydroxymethylbilane synthase|EC 2.5.1.61|Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)|TrEMBL
MIVGTRGSPLALKQTYYVVNQLSKLVNEEVKIKIIKTTGDKIKDSQLHKIGQRGVFTKEI
DKAVLNEEVDLAVHSLKDVPTELHEDLEIVAIPHRDSPNEVLVSKYSWDELSEECILGTS
SLRRKAFCRYHGKKFKIKPLRGNIETRIKKVEDGEYDATIMAEAALKRLNLEKYIKKRFS
VKYFTPSAGQGAIAIETRSDSKYISVLKKLNDHRAFYEVTAERTVLKELGVGCQWPIGVV
ARSKGKNLNLYAILLSKKGKLLSKIELDGKLHEATKLGKKAAKKMEGYI
>E6VY17|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2)|TrEMBL
MKQLTIATRGSALALWQANHIKDRLEAEHPGLTVHLLKIKTKGDKILDVPLAKVGGKGLF
VKEIEEALLDGRAQLAVHSMKDVPTELPEGLEVGVIPEREASTDSLLSVKYEGLAGLPRG
AVVGTSSLRRQSQLATLRPDLKIESLRGNLDTRVRKLLAGEFDAIVVATAGLNRLELTAP
KHEILGPPDFLPAVAQGALGIEYHSANAEVAAMLQFLNHEPSKRQVLAERGFLTGLDGGC
QVPIAAWSVIDGERLRLTGFVADVDGSRPIRMTAEGPVDNAWDIGAALAEKVLAAGGKAI
LDEVYAREGR
>H4ADV3|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1165|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H7VM66|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli LMG 23344|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKILKFFKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>H5JQQ5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC12C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H0DG58|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus pettenkoferi VCU012|TrEMBL
MRKLVVGSRRSKLAMTQSRQFIDSLKKVDPSLEIEIKEIVTKGDQIVDKQLSKVGGKGLF
VKEIENELYSHEIDMAIHSLKDVPSVISEGLTLGCIPDRENPFDAYVSNDHVALEDLPEG
SIVGTSSLRRGAQIKAKYPHVEIKWIRGNIDTRLQKLQDEDYDAIILAAAGLKRMGWSDD
IVTSYLDKETLVPAIGQGALGIECRSDDQELLDLLNQVHNQNVADCVTAERTFLKQMDGS
CQVPIGGYATKDDDGTIEFTGLIMSTDGKERYQHTARGKDPVQLGQEVSQVLKDQGAYEI
IRKLNEEL
>F5P9B7|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri K-304|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>H7XGZ1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni LMG 23218|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>Q4WYI1|hydroxymethylbilane synthase|EC 2.5.1.61|Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)|TrEMBL
MSLDDKYIPIFYGLCRNPSPLNFQPPSSSDNMVETSPTPQLPLRIGTRRSNLAMVQTEGI
RDRLQKIGPDRTYEIEALRTAGDRDQLTALYDFGAKSLWTTELEEKLTSGELDVIVHCLK
DMPTTLPDTCELAAIPPRDDPRDALIIKAGLPYTSLKSLPEGAVVGTSSVRRSAQLRRLY
PHLRFANLRGNVETRLAKVDDPHSEYMCMVMSAAGLERVGLKHRISQYLGSRDGGILYAV
GQGALGLEIRKGDRKMQELLGQLADRKSTLACLAERSLMRTLEGGCSVPIGVETEWMSSG
DLRMDAIVVSLDGTRSVEDRITARVEAIDEADALGEELAGRLLEAGAGEILKDINANRPS
KD
>I2HHZ2|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis NM220|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
ERIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>A3W2Z8|hydroxymethylbilane synthase|EC 2.5.1.61|Roseovarius sp. 217|TrEMBL
MTRNLPTPSHPLKIGTRGSPLALAQAFETRARLGAAFDLPEEVFEIVVIKTTGDQIIDRP
LKEIGGKGLFTREIEQALLTGEIDIAVHSMKDMPVLQPEGLLLDTYLPREDVRDAFVSPL
VGSLADLPAGALVGTSSLRRKAQVLVAYPHLQVVEFRGNVQTRLKKLADGVATCTFLAMA
GLNRLGRSEVATGAIDPEVMLPAVAQGAIGIERRADDTRAAEMLAAIHHKETGQRLVSER
AFLAALDGSCETPIAGLAELNGNTLRLRGEILRPDGSESLTDDQSAPIEDGADLGRAMAA
KLLAQAGPGFFDWRS
>D1YQC6|hydroxymethylbilane synthase|EC 2.5.1.61|Veillonella parvula ATCC 17745|TrEMBL
MRDHIRIGTRKSALALWQAEHISAELQRLYPNITVELVHFNTKGDRILEKPLAQVGGKGL
FTAELEEAMHAGDIDIAVHSLKDMPTELPEGLTLGAISAREVPYDALVSPVYKTLDKLPQ
GARVGTSSLRRQAQLLHVRPDLKVEVIRGNVQTRLSKIETEKLDGVILAQAGLKRLGLED
QITQVFKADEMIPAVGQGALAIECRADDTEMLDMLDPINDEATRYAVEGERSFLRQLNGG
CQVPMGVHGTINKGQLTLKAMIASLDGKTVYEGEISGPAKKGEILGKNLAKALYEEGGKR
IVDALIEEGIIK
>Q1QSV5|hydroxymethylbilane synthase|EC 2.5.1.61|Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)|TrEMBL
MQTLRIATRQSRLALWQAEHVKARLLALHPGLEVELVAMTTRGDKILDSPLAKVGGKGLF
VKELEEALLDGRADIAVHSMKDVPMHFPEGLGLSVILESGAPTDAFVSNDYASLDALPEG
VRVGTSSLRRGLQVKEARPDLEVLNLRGNVQTRLGKLDGGEFEAIILATSGLQRLELGHR
ITQELPPEVSLPACGQGALGIECRHDDESLLELLAPLDHPQTATRVRAERAMNTRLDGGC
QVPIGGYAVLEDGDRTLWLRALVGDPDGSRVLRAEGRGSADEPEALGVRIAESLLDQGAG
DILAQVYDQGE
>E8H1N2|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008287|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H4G5Y2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-160|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>H2G0Z8|hydroxymethylbilane synthase|EC 2.5.1.61|Oceanimonas sp. (strain GK1)|TrEMBL
MANRIIRIATRKSLLALWQAHYVKDRLEALHEDVTVELVPMTTQGDVLLDTPLSKIGGKG
LFIKELEQAMLDGRADIAVHSMKDVPVEFPEGLGLTVICEREDPRDAFVSNHYQSLDELP
AGAVVGTASLRRECQIRARRPDLVVKTLRGNVQTRLRKLDDGEYDAIILAAAGLKRLALE
ERIAGLLSPEDSLPANGQGAVGIECRLEDAELLELLAPLDDRDTRLRVEAERAMNQGLQG
GCQVPIGSYALLEGDQLWLRGLVGRPDGTEVLFDEVRGPAEQGKALGAELAKRLLAAGAD
KILAEVYSS
>D8NR29|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia solanacearum CFBP2957|TrEMBL
MSSNARPTSVESPLAAQAPTRLVIASRESRLAMWQAEYVRAALQKYYPACDVSILGMTTR
GDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMELPPGFALPAILEREDP
RDAFVSNQYADLAALPAGAVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLAKLDRGDY
AAIILAAAGLKRLGLSERIRAVIASDVSLPAAGQGALGIETRADRTDVQAWLAPLHHLPT
ALAVTAERAVSRRLGGSCQVPLAAFAHWTDAGALRLRAFVASQDGRRKLAAEGEATPATL
AEAEALGAHVAQQMLDGGARDILATLGADAPPAT
>H3XDE9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-24|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>G8LZ98|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium clariflavum (strain DSM 19732 / NBRC 101661 / EBR45)|TrEMBL
MKTVRVGSRDSGLAVIQAQMVIDAIKKYDSNIEVELVTMKTTGDRILDKTLDKIGGKGLF
VKELDEALRNGGVDITVHSYKDMPMEINSELPVVALSEREDERDVLILPANQGDKSKPLG
CSSKRRMLQLKALGFDNIEPLRGNVITRLKKLDDGEYCGIILAAAGIKRLGLENRISRYF
TTEEIMPAACQGIIAVQTRKGEDTRYLANFHSERSKIVSDAERAFVAALDGGCSSPVAAY
AYFENDKLVLRGLYVNEEKNIAIKGIEYGRAEDAVKMGISLAKRLKGEAC
>I3DXU3|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus methanolicus PB1|TrEMBL
MRKIIVGSRRSKLALTQTNWVIEQLKKLAPSFDFEVKEIVTKGDKILDVTLSKVGGKGLF
VKEIEQAMLNKEIDMAVHSMKDMPAVLPEGLMIGCIPEREDHRDALISKNHIPLKELKLG
AKIGTSSLRRGAQILANRPDLEIKWIRGNIDTRLAKLETEEYDAIILAAAGLSRMGWASE
VVTEFLETDVCLPAVGQGALAIECRSDDSELLQLFEKLTSEKTSRAVRAERTFLQKMEGG
CQVPIAGYAFINDNDEIVLTGLVASPDGKEILKERAAGHNAEELGKCVADKLIEKGAKAL
IEKVKREQESV
>B5PXM1|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Hadar str. RI_05P066|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKY
HSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAG
LKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEE
LLENGARAILTEVYNGETPA
>E1Q4S0|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain PeCan4)|TrEMBL
MEKLVIGSRGSELALWQANHIKERLKKECSMESEIQIVKTTGDKILDAPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACTTKRADVRDTFLSMKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLERAFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEAFLQSGAKEIL
EKAQLF
>Q1JV99|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfuromonas acetoxidans DSM 684|TrEMBL
MSTKIKIGTRRSKLALWQAYYVEQLLQDAGMDTEIVEIDTRGDQVLDVSIAKIGSKGVFT
EELEDQLRSGDIDIAVHSAKDMQSELPEGFEIIAFTIREKVNDVVVSRDKSIRLGDTSRP
LTIGSSSVRRRAILKAYYPHLNIIEMRGNLQTRIGKMDDGQCDAILLAYAGVNRMEYNDL
IVETLPLEQFIPPVGQGSVAIESAINLDAKKRETIRKAVNHPDTEFRLLAERAFLKTLKG
GCSIPAFCMAELEGDDQLKVTGGMISLDGQTLIKNVLTGARSDAEQLGDQMANLTLEQGG
AQILAAIRAERGE
>A6UDR5|hydroxymethylbilane synthase|EC 2.5.1.61|Sinorhizobium medicae (strain WSM419)|TrEMBL
MVSSLNRFRFKQPRSNNGWQRMQTKPFRIGTRGSPLALAQTHETRDRLAAAHGLPVEMFE
IVTLSTKGDRITDRSLAEIGGKGLFTEELEQQLLSGDLDFAVHSSKDMTTKLPDGLFLSA
FLPREDVRDAFVGRSATRLAELPQGATVGSSSLRRQALIRRLRPDVNVITYRGQVETRLR
KLAEGQVDGTLLAYAGLRRLGMAHVPTELLDPESFPPAPAQGAICIEARLGDDRINALLS
AVDDPRTHEAVSCERGFLATLDGSCRTPIAGYAQSDGARIRFSGMILTPDGTTCHRIETD
GRTADAAALGREAGERIRAKAGPEFFLSWS
>F1ZXR0|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoanaerobacter ethanolicus JW 200|TrEMBL
MKKVIKVGTRSSELALKQTAMVINEIKKFRQDFEFEIVKITTQGDALIDKPVSEIGGKGV
FVKEIESALLKGEIDMAVHSMKDMPYEIPKGLKLMAVLKREDPKDVFVSRDGTQFMDLKE
GAKIGTSSLRRQVQLKALKPDIQIVPIRGNVRTRLKKMEELNLDGIVLSAAGLHRLGLEN
IITEYFPPDVVVPAPCQGILSVEIAESFDNIFQEFYPYIVDRKTFFEASVERELLKAFGV
NCRQPFGAYAQYRKEEDEEKINIKVAYQKENKLLKSEATGLIEETDKMIEKLIEEFGGI
>H0CQJ9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21334|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H4L589|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC2D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I0XZW7|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia sp. SJ98|TrEMBL
MNSETHSTTPPASIIIASRESRLAMWQAEHVRCALHKLYPSCDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELEAALAEGRADLAVHSLKDVPMELPEGFTLGAIMEREDPRDAFVSPH
YASLDALPAGSIVGTSSLRRESMIRARFPHLEVRPLRGNLDTRLAKLDRGEYAAIILAAA
GLKRLGLEARIRALLDPSESLPAAGQGALGIEIRADRADLAAWLAPLHDENTALAVEAER
AVSRALGGSCEVPLAAYAVWRDGALHLRGAVSMPDGKRVLRAEESVQAPDLAAALALGQR
VSSDLEAQGAMDIVAALSTMSRADGPNTAPSGPKS
>I4C6T6|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfomonile tiedjei DSM 6799|TrEMBL
MKKKLTIGTRGSALALWQARYVASVIEERDPAIQVELKIIKTRGDKILDAPLALIGGKGL
FTKEIEDALLERSVDLAVHSMKDVPTELPDGLRIAAVMEREDPRDVFISANGQDLEKLPQ
GSRIGTSSLRRKAFLLNRFPGLDIISIRGNVDTRLRKIETEHLAGIILAAAGVLRLGFQQ
RITSFLDTGFMIPAIGQGALAIETRMNDPEVESVVRSLNHADTELCVRIERAFLLRMGGG
CQVPMAAHCTKKDGAVHVNAAVVHPDGSPLLKETFSGKVENGSIGVELADTLIQRGADAI
LKTVLSDDWEPGPAMDIV
>B5NHL9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Javiana str. GA_MM04042433|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKY
HSLDDLPAGSIVGTSSLRRQCQLAERHPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAG
LKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEE
LLENGARAILTEVYNGETPA
>E1VXL3|hydroxymethylbilane synthase|EC 2.5.1.61|Arthrobacter arilaitensis (strain DSM 16368 / CIP 108037 / JCM 13566 / Re117)|TrEMBL
MSESFRVGTRGSALATTQTGWAAQKLAGISGLDVETVLVKTEGDVVTGSLATLGGTGVFA
AALRQHLLDAGCDLAVHSLKDLPTAQPEGLVLAAIPAREDVRDALCSRDSLGLDQLPHGA
KIGTGSPRRAAQLLAYRSDFEIVDIRGNVPTRLGRVKGVGKTLDDGSVGRSTQGDLDAVI
LAAAGMRRLGLEDHITEYLDPSIMLPAPGQGALALETRSAGSGHQALDAALSQFDDAHTR
MQVEAERALLSTLEAGCAAPIGALAHIDGDDLVLEAVACNPDGSETMRRSARIACSTTDA
AQQLGRSLAQSMIADGAAVVAGLA
>I2RDF4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 1.2741|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLNDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>B7I341|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii (strain AB0057)|TrEMBL
MFDQPMLEFMKTLKIATRQSPLALWQAEHIRARLQERHPDLTVELVKFVTQGDKILDTPL
AKIGGKGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQF
EKFADLPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAG
LKRLGLAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLALIQPLLHPETDVCVRAERA
FNAYLEGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARN
LLDQGAGDLLKALY
>F6E405|hydroxymethylbilane synthase|EC 2.5.1.61|Sinorhizobium meliloti (strain AK83)|TrEMBL
MQTKPFRIGTRGSPLAMAQTHETRDRLAAAHGLPPEMFEIVILSTKGDRITDRSLAEIGG
KGLFTEELEQQLLSGDLDFAVHSSKDMPTKLPEGLFLSAFLPREDIRDAFVGRSAKRLVD
LPQGATVGSSSLRRQALIRRLRPDIDVITYRGQVETRLRKLAEGQVDGTLLAYAGLRRLG
MEHVPTELLDPEEFPPAPAQGAICVEARIGDDRINTLLAAIDDPRTHEAVSCERGFLATL
DGSCRTPIAGYAQSDGTHIRFAGMILTPDGTTSHQIEIDGRAADAERLGQEAGERIRAKA
GPGFFSSWS
>H4ZLH4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC8B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C9PSC4|hydroxymethylbilane synthase|EC 2.5.1.61|Pasteurella dagmatis ATCC 43325|TrEMBL
MTNNTLKIATRQSPLALWQANYVKQRLESFYPDLNVVLVPMVTKGDVILDTPLAKIGGKG
LFVKELEIALLSGEADIAVHSMKDVPMQFPEGLGLSVICPREDPHDALVSNTYRTLEELP
QGAIVGTSSLRRQCQLKQLRPDLKIESLRGNVGTRLSKLDCGDYDAIILAAAGLIRLGLT
ERIASFIDIQDMLPAAGQGAVGIECRKNDSRVQQLLAPLADIETTDCVLAERAMNTHLQG
GCQVPIAGYAIIENDQIYLRGLVGALDGSAILRAEAKSAVKNAENLGIQVAEMLLQQGAG
NILKVLYSAKN
>D0IMG2|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio sp. RC586|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEVAMLEGRADLAVHSMKDVPVDFPQGLGLVTICEREDPRDAFVSNTYVKIDDLP
SGAVVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLGLE
SRIRNFIEPEQSLPAVGQGAVGIECRLDDQRVRELLAPLNHTDTADRVRCERAMNLTLQG
GCQVPIGSYALLDGDDIWLRALVGEPDGSQIVHGEIRGPRSEAEQLGITLAEQLLEQGAK
EILERLYCEHE
>B7JYW7|hydroxymethylbilane synthase|EC 2.5.1.61|Cyanothece sp. (strain PCC 8801)|TrEMBL
MAVSSPTRSIRIGSRKSQLALVQTYWVQKELQRHHPQHQFDVETMSTQGDKILDVALAKI
GDKGLFTKELEVAMEQNQVDLAVHSLKDLPTNLPTGLILGCVTERVDPADALVVNKKHLD
KQLDTLPEGAVIGTSSLRRLAQLRHHFPHLTFKDVRGNVNTRLKKLDEGEYDAIILAVAG
LQRLDMSDRIHQVIPSEISLHAVGQGALGIECREGDEEVLALLKVLEHEPTRDRCYAERA
FLRELEGGCQVPIGVNTEIEGDTLTLTGMVASLDGQTLLKDTISGPRESAEQLGRDLANR
LREAGAGEVLAAIFAQIERG
>F4FEJ5|hydroxymethylbilane synthase|EC 2.5.1.61|Verrucosispora maris (strain AB-18-032)|TrEMBL
MSQRQPSGPLRLGTRGSKLAMAQSGHVAEALTARTGRPVELVEVITAGDRSSAPVHRLGV
GVFVSALRDALVAREIDFAVHSYKDLPTAMPAGLHIAAVPPREDPRDALVARDGRTLAEL
APGASIGTGALRRIAQLHALGMQLSVSPIRGNIDTRLARVLGPDADLDAIVLARAGLARI
GRLDVITETLDPMLMLPAPAQGALAVECRVDDPEMVELLGTLDHAASRATVTAERAMLAT
LEAGCSAPVAAYAVVAEGEPTGSGVEGDVVQEIYLRGAVISPDGSRDIRLSRTGTLADAA
EIGKALATELLDLGADSILGPQGHNGPGTQQFGSTE
>D6SIV4|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus MN8|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>H1QVC1|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio fischeri SR5|TrEMBL
MSQQLPVRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQLKEARPDLIIKELRGNVGTRLQKLDDGNYDAIILACAGLIRLGL
EDRIKSAIEPEQSLPAVGQGAVGIEARLDDDRLRTLLEPLNHPETANRVLCERAMNNRLE
GGCQVPIGSYSLIDGDQIWLRALVGEPDGSVMIRGEVSGPVSDAEALGTQLADQLLNDGA
KEILERLYAEA
>A1K455|hydroxymethylbilane synthase|EC 2.5.1.61|Azoarcus sp. (strain BH72)|TrEMBL
MTSTTSSSPAAPERIVIATRESRLALWQAEHVKARLEALYPACTVELLGMTTRGDQILDR
PLAKVGGKGLFVKELETALLDGRADIAVHSMKDVPMEMGKAFALPCISAREVPLDAFVSN
RYASLADMPPGTVVGTSSLRRESQLHAQYPFLAVTSLRGNLDTRLRKLDEGQYDAIILAA
AGLTRLGLADRIRATLPAEVSLPAAGQGALGIECLSSRPEVAAWLAPLNDPATSACVRAE
RAVARALAGSCEVPLGAYAELRGARLWLRGFVARPDGSEIVRAEREGDPAAAEALGGALA
DDLRAQGAERILAELG
>Q2B6L0|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus sp. NRRL B-14911|TrEMBL
MRKIIVGSRRSKLALTQTNWVMDQLKKIDDSFEFEVKEIVTKGDQILDVTLSKVGGKGLF
VKEIEQAMLDEEIDMAVHSMKDMPAVLPEGLVIGSIPEREDHRDALISKGHQTLDQLKPG
AVVGTSSLRRGAQLLAKRPDLEIKWIRGNIDTRLAKLETEEYDAIILAAAGLSRMGWTTD
TVSEFLEPEVCLPAVGQGALSIECRESDKELLELLSKFTCGTTNQTVRAERAFLHKMEGG
CQVPIAGYAVLNEKDEIELTGLVASPDGKTIYKEKVTGADPVEVGLRTAEKLIEKGAKKL
IDDVKKELDGE
>F4AK65|hydroxymethylbilane synthase|EC 2.5.1.61|Glaciecola sp. (strain 4H-3-7+YE-5)|TrEMBL
MSDRVIRIATRKSTLAMWQAEYVQAKLLEAHPQLKVELVPMSTQGDRILDTPLAKIGGKG
LFIKELEIAMSEGRADIAVHSMKDVPVDFPDGFGLHCICERENPYDAFVSNTYSAIEELP
QGAVVGTSSLRRQCQIRSARPDLTIRDLRGNVNTRLAKLDEGQYDAIILAAAGLIRLNMQ
ERIKAYIEPTVSLPAVGQGAVGIECRNDDAELIELLKPLNHADTESRVKAERAMNAKLNG
GCQVPIGSYAVLNGDELYLRGLVGSPDGSLLLQAEKRGSINDAQSIGIDVAEQLLEKGAG
DILQALYKD
>F3MER6|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus sp. HGF5|TrEMBL
MRTIVVGSRQSALALTQTGQVIDDLKRLAKEHGLEYDFAVKKIVTKGDRILDVTLSKVGG
KGLFVKEIEQAMIDGEIDMAVHSMKDMPSVLPEGLVSGAVPARKDPRDCLISKEGTTLDD
LPQGAKVGTSSLRRSSQLKAYRPDLQIDWIRGNIDSRIRKMEEGEFQAIILATAGLQRMG
WEDRITSYLPVEVSLPAVGQGALGIECRENDEELLHLLSLYNDEVTARTVAAERKFLSEL
NGGCQVPIGAYAVMKNVEAGDSRGEQNVIQLTGMVGSPDGEIVLKESAEGTDPEALGVEV
AAKLKAKGAEKILAQVRG
>F7ZA91|hydroxymethylbilane synthase|EC 2.5.1.61|Roseobacter litoralis (strain ATCC 49566 / DSM 6996 / JCM 21268 / NBRC 15278 / OCh 149)|TrEMBL
MTVKLPSPDSPLKIGTRGSPLAMAQAFETRARLMQAFDLPEDAFSIVVIKVTGDMIQDRA
LKDIGGKGLFTREIEEDLLSEKIDIAVHSMKDMPTLQPDGLVLDTYLPREDVRDAFVSPT
LSGIADLAQGAVVGTSSLRRKAQLLNRRPDLNVVEFRGNVQTRLKKLADGVAECTFLASA
GLNRLKMDEVPATPIEADEMLPAVAQGAIGIERRMADQNTADLLSAIHHIETGQRLTAER
SFLLTLDGSCETPIAGLAELDGDQLRLRGEVLRPDGSESLAGERSGPIADGAEMGRILAQ
ELLDRAGPKFFEWH
>D5VVY9|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum (strain 230613 / Type F)|TrEMBL
MNFIIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPKREDVRDAFISLDNIKFKDLRKGAK
IGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLEHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
>D1B2M2|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurospirillum deleyianum (strain ATCC 51133 / DSM 6946 / 5175)|TrEMBL
MKKLIIATRGSKLALWQSEHVKAELEKAHPHLAVELSIMMTKGDKILDTPLAKIGGKGLF
TKELEEAMLRGEAHIAVHSLKDVPMEFPEGLKLGVITKREDVRDAMLSEKYGCLEDLPQG
AVVGTTSLRRRMQLLKLRPDFVIKNLRGNVNTRIRKLKEGEFDAIILASAGIKRLGLQEE
VRYFTPISKEVMIPASGQAALGIEIVDNAEVERLVSVLKDEDAMIETRVERDFVTLLEGG
CQVPIGVNAEVTQESLHVKAILGLPDGSQMMCEVMSGKREEFETLGKVLAQKVIDKGAKE
LLARAEKIALSEIF
>E3XW14|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 2362-75|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F8G7U0|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella sp. (strain TX077308)|TrEMBL
MKQIVVASRESKLALWQTNFVKDRIQNELSIPCQISTMKTQGDIILDKPLNKIGGKALFM
KELEIAMLNGKADIAVHSLKDVPYQLPDGFCLASFMPREDPRDAFVSNKYSSIDDLPKGA
IVGTSSLRRKAQLLNYRDDLIIRDLRGNVVTRLSKLDGDEYDAIILASAGLIRLELNDRI
TQYIPVEISLPAVGQGIVVVEALSENSELLEKLQNLNCSDSFCVATAERAFNQELKGGCH
VAIGAYAELQGNQITLTAMVASSDGKNILKRKLIGEDPIKLGKSLAQEMIELGAYTILEK
>H5W3Q6|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Enteritidis str. LA5|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHS
LDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELL
ENGARAILTEVYNGETPA
>I2N3X0|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces tsukubaensis NRRL18488|TrEMBL
MTDRALRLGTRRSKLAMAQSGQVARAVEALTGRSVELVEITTYGDTSREHLAQIGGTGVF
VAALREALAAGEVDFAVHSLKDLPTAQPAELVLAAIPKREDPRDVLIARDGLTFDRLPEG
ARVGTGSPRRAAQLNAYARAHHTRIETVPIRGNVDTRIGYVHSGELDAVVLAAAGLNRMG
RSAEVTDFLSVDFVLPAPGQGALAIECPAHDTELIAVLAELDDPVTRVAVTAERSLLAAL
EAGCSAPVGALADLLGDGQAVTEMRLRGVVGTTDGATLVQLSVTGPVPTSHGDAIALGRE
LASEMLAKGAAGLMGERAS
>I2N3X0|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces tsukubaensis NRRL18488|TrEMBL
MTDRALRLGTRRSKLAMAQSGQVARAVEALTGRSVELVEITTYGDTSREHLAQIGGTGVF
VAALREALAAGEVDFAVHSLKDLPTAQPAELVLAAIPKREDPRDVLIARDGLTFDRLPEG
ARVGTGSPRRAAQLNAYARAHHTRIETVPIRGNVDTRIGYVHSGELDAVVLAAAGLNRMG
RSAEVTDFLSVDFVLPAPGQGALAIECPAHDTELIAVLAELDDPVTRVAVTAERSLLAAL
EAGCSAPVGALADLLGDGQAVTEMRLRGVVGTTDGATLVQLSVTGPVPTSHGDAIALGRE
LASEMLAKGAAGLMGERAS
>H8C4G6|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1577|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>A9HK97|hydroxymethylbilane synthase|EC 2.5.1.61|Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)|TrEMBL
MVSAPPSVPGPSAAPSSALQKIAAQAAARQKQAATRAALPHRRELPLRVGTRASPLALVQ
TRAFLTMLTRFCPVLRDMGAFQEHQINTTGDQVQNRRLAEIGGKGLFAKEIHDALSDGRI
DFAVHSLKDLETTLPPGLVLACTLRREDARDALILGPGAGGRHDAADAADPYAALPRNAL
VGCASVRRQAQMLHVRPDLRFGLLRGNVQTRLDKLAARQCDATLLALAGLRRLGMEDRAD
IVLDPEIMVPAAGQGIVGVTVRESDVELRELLAAIEDYEARAVATAERALLAELDGSCRT
PIGGYARLVPGLAGAEASLRLTGLVAREDGSFLLRRTVTGLRADAEEMGRELGRSLRMDS
PSDVFAA
>H4VNM1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC6C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F3IN54|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. lachrymans str. M302278|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFESLDALP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYNAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRLIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGRVLLHADARAPQTSAQALGVQVAEALLAQGAA
EILKAVYGEANNE
>H4AUP4|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1769|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>G0HSE0|hydroxymethylbilane synthase|EC 2.5.1.61|Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)|TrEMBL
MTTRGETLQLATRGSDLALRQAATVRDSLSSRRLSVELVEVETTGDQIRDELIHRLGKTG
AFVRSLDEKVLDGELDAAVHSMKDMPTERPERLVVAAVPERAAAEDVLVTPDGRSLDELP
EGATVGTSSLRRKAQLLAERDDLTVEPLRGNVDTRIAKLLAPSLQQEHQERHEAEQEHKG
DAGDGDDADLDADEEEEHPYDRTVEEWFDDLTEFERRAMERDPDVEYDAIVLAKAGLHRA
GLTRYVGMSDLDPDRFVPAPGQGALAVTAVDGDLALDIKDRLDDPQTRVETTVERTILEE
LGGGCVAPIGVHAHLEGGVVHTRVRVLSQDGTEEVSVGRDIPAEYHIDAAQDLAAELAEQ
GADDLIAEAKRDSTEADDDASTAREEDEE
>I0E7Q4|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori Shi169|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIRAVLGLPNGKEVIAKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKAQLF
>H8JI83|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium intracellulare MOTT-64|TrEMBL
MANVIRIGTRGSLLATTQAGVVRDALIALGHPAELVTITTAGDRSSGPIESLGVGVFTTA
LREAMEEGRVDAAVHSHKDLPTADDPRFAVAAIPVRNDPRDAVVARDGLVLGELPPGSLV
GTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTE
TLEPVQMLPAPAQGALAVECRAGDTRLAAVLAELDDADTRASVTAERTLLAELEAGCSAP
VGAIAEVVESIDEEGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFE
LGARELMRGARQDPTRGN
>H8JI83|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium intracellulare MOTT-64|TrEMBL
MANVIRIGTRGSLLATTQAGVVRDALIALGHPAELVTITTAGDRSSGPIESLGVGVFTTA
LREAMEEGRVDAAVHSHKDLPTADDPRFAVAAIPVRNDPRDAVVARDGLVLGELPPGSLV
GTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTE
TLEPVQMLPAPAQGALAVECRAGDTRLAAVLAELDDADTRASVTAERTLLAELEAGCSAP
VGAIAEVVESIDEEGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFE
LGARELMRGARQDPTRGN
>F2CEN0|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK408|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKKLHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQAGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLNRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRQLLATVQDEKTAAEVAVERVVLAQM
NADCTFPIAAFAQKNGQDYQLEAMLAKEDGQCVFVSLKGQDGQQLAEQAVRQLADKGAVG
MPWLKK
>Q2RND3|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)|TrEMBL
MMTAIEKSKLRIGTRGSPLALAQTHQVRDLLIAANPDLGEPGAVTIEVIKTTGDAILDRP
LSELGGKGLFTREIDDAMLAGTIDIAVHSMKDVPTYLPDGIVLPCMLEREDVRDAFLGRD
HARLADLPEGSVVGTASLRRGAQILAMRPDIKVISFRGNVQTRLDKLARGEADATMLAIA
GLNRLGMADKASSVLEIDEMLPAVAQGAVGVTCRAGDETAHRWLAPLNHRATQLCVEIER
AFLTRLDGSCRTPIGGLARLKRVEDPSGTVFFRGMIIRTDGKVIHQTTREGLAADGIALG
DDAGAELLAKAGPGFFQVGAL
>G9A2G1|hydroxymethylbilane synthase|EC 2.5.1.61|Rhizobium fredii (strain HH103)|TrEMBL
MQTKPFRIGTRGSPLALAQAHETRDRLAAAHGLSPEMFEVVVLSTKGDRITDRPLAEIGG
KGLFTEELEQQLLSGELDFAVHSSKDMPTNLPDGLFLSAFLPREDIRDAFVGRTAPRLVE
LPEGATVGSSSLRRQALIRRLRPDINVITYRGQVETRLRKLAEGQVDGTLLAFAGLKRLG
MTAVPTELLDPKEFPPAPAQGAICIESRVGDERVNALLAAIDDPRTHEAVACERGFLATL
DGSCRTPIAGYAQSDGTHIRFSGMILTPDGTTSHRVEIDGKAQEATELGRKAGEEIRAKA
GPGFFSSWT
>G8WD95|hydroxymethylbilane synthase|EC 2.5.1.61|Klebsiella oxytoca (strain ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686)|TrEMBL
MLDKVLRIATRQSPLALWQAHYVKERLESCHPGLSVELVPMVTRGDVILDTPLAKVGGKG
LFVKELELAMLEGRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNHYASIDELP
HGSIVGTSSLRRQCQLAAARPDLTIRSLRGNVGTRLGKLDSGEYDAIILAAAGLKRLNLE
ARIRQPLSPEQSLPAVGQGAVGIECRLDDEWTKTLLAPLNHTETAIRVRAERAMNTRLEG
GCQVPIGSYAELIDGELWLRALVGAPDGSHTVRGERRGCPEDAERLGVALAEELLDNGAR
DILAVVYAGEAPQ
>D2ALB6|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. tularensis (strain NE061598)|TrEMBL
MKQITIASRESKLALWQTNFVKNRIQLELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>G2FEZ4|hydroxymethylbilane synthase|EC 2.5.1.61|endosymbiont of Tevnia jerichonana (vent Tica)|TrEMBL
MWQAEHVAAELKRAHPGLEVELLGMSTQGDKILDTPLAKIGGKGLFVKELEQAMLEGRAD
IAVHSMKDVPAELPEGLHLPVIMQREDPRDAFVSNQYSSFESLPEGARVGTSSLRRQCQL
AEARPDLQIKPLRGNVNTRLRKLDEGEYDAIILASAGLKRLGFEQRITAFIAPEQSLPAI
GQGAIGIECRSDDAQVNALIAPLHHVDTAACVHAERAMNNRLMGGCQVPIAGYAMLEAGN
LWLRGLVGEIDGSQILRGEAEGTPDEAESLGVGLAERLLEWGADEILSTLYAD
>B5J1T1|hydroxymethylbilane synthase|EC 2.5.1.61|Octadecabacter antarcticus 307|TrEMBL
MKFEMPTPAAPLKIGTRGSPLALAQAHETRARLMVAFDLAEAAFEVCVIKTTGDDRSLID
ADIPLKVIGNKGLFTKEIEEAMLAGQIDIAVHSTKDMPVAQPDGLVLDVFLPREDARDAF
VSVKYSGIPDLPEGAIVGTSSLRRRAQLLAKRPDLTVVEFRGNVQTRLKKLADGLADATF
LAMAGLNRMGMDDAAMGAIDLADMLPAIAQGTISIERRIDDLRARDMLAAIHDVQAGQQM
AAERSFLAALDGSCETPIAGLAMIDGDNMWLRGEILKPDGSQVFTGERRGLVTEGRAMGK
ELAQELLGQAGPDFFVAVDAG
>E8FVA6|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008283|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>C0W553|hydroxymethylbilane synthase|EC 2.5.1.61|Actinomyces urogenitalis DSM 15434|TrEMBL
MSTVRLGTRGSALALTQSGLVARMLEQAAALAGQELHVELVPVRTRGDVDPTALSQLGGV
GVFATALREALLAGECDLAVHSYKDLPTAAVPGLRIAAVPAREDPRDVLCTRAATLGLHD
LPAGARVGTGSPRRSAQLLAQRPDLTIVPIRGNVPTRLARVVGSVVSADGPMGATAEPDL
DAAILALSGMRRLGLEDYASQPLAARCGARSQVEVQGIPDGGSAAGSPATTEPWMLPAAA
QGALAVETRDRVSCELPVLTVALALVDDPVTRACADAERSLMRCLAAGCAAPVGALARPL
DVAGEPAAGRDLPTEPGTALEPGPDQAPAICLEALVASLDGTQLRRASATGTLEEAEDLG
RCVAERLLADGAAQITDLQASKGSPGAGSTGPQAAAKGTDRR
>C0W553|hydroxymethylbilane synthase|EC 2.5.1.61|Actinomyces urogenitalis DSM 15434|TrEMBL
MSTVRLGTRGSALALTQSGLVARMLEQAAALAGQELHVELVPVRTRGDVDPTALSQLGGV
GVFATALREALLAGECDLAVHSYKDLPTAAVPGLRIAAVPAREDPRDVLCTRAATLGLHD
LPAGARVGTGSPRRSAQLLAQRPDLTIVPIRGNVPTRLARVVGSVVSADGPMGATAEPDL
DAAILALSGMRRLGLEDYASQPLAARCGARSQVEVQGIPDGGSAAGSPATTEPWMLPAAA
QGALAVETRDRVSCELPVLTVALALVDDPVTRACADAERSLMRCLAAGCAAPVGALARPL
DVAGEPAAGRDLPTEPGTALEPGPDQAPAICLEALVASLDGTQLRRASATGTLEEAEDLG
RCVAERLLADGAAQITDLQASKGSPGAGSTGPQAAAKGTDRR
>A7HA36|hydroxymethylbilane synthase|EC 2.5.1.61|Anaeromyxobacter sp. (strain Fw109-5)|TrEMBL
MIRIATRRSPLAKWQANHVADLLRAKEPGLEVRLHELVTKGDRILEVPLAEVGGKGLFVK
EIEDALLASDAEIAVHSMKDLPAELAPGLAIGAVPEREDPRDALCSPRYKTLAGLPRGAK
VGTSSLRRGAQLKALRPDLQLEMVRGNVETRLRKASEALDAVVLAYAGLRRLGLAEHATY
VFPAEEMLPAVAQGALALEARAADAPTMARLAALEHPETRVRIEAERGFLGRIEGGCQVP
IAGHATVQGGRVSMRALVASLDGTRVIRGERSGPAADARQLGIALAEELLSKGAAEILRE
CEGKAPGLAAPRR
>Q2ISU9|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodopseudomonas palustris (strain HaA2)|TrEMBL
MKIPVRIGTRKSVMALAQTEDIANQLRAAASELDPEIVRFETVGDSDQVSKLLPHGGKGG
AFVAEIRAAMLRGELHCAMHSLKDMPANEETPGLIVAATLARDPANDSMVLRKGLTLDEL
KASRGKGYTIGTNAVRRAAYAKRLFPEVEVIHFRGAADTRIRKLDNREKQRMPDGGEVGP
ADALIMARSGLERVGFVDRIVHDFTPQEMLPAAGQGIVAVECPVHEWQTRKYLALIDDPK
ARLFCDAEREVLWVLNGHCNSPMAAYSTINGSEMTLSASVLDEAGGLFIEATRTGPANRP
RELGRTVGLDLLDKGAAAIIEKTRPE
>G0TPM0|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium canettii (strain CIPT 140010059)|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTADDPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>A1R8A1|hydroxymethylbilane synthase|EC 2.5.1.61|Arthrobacter aurescens (strain TC1)|TrEMBL
MTVRIGTRASKLALTQTQQTADQLAAVGGFPVELVHIKTEGDVKTGSLSQMGGTGVFVAA
LRDALLADACDVAVHSLKDLPTGAALGLSIAATPKRVDVRDVLCARDGMTLAQLPGGAKV
GTGSPRRAAQLRAARPDIEVLDIRGNVDTRLGRVPGLPGNTTDEVVQGKSCDLDAVVLAA
AGLERMDRLDTVSEFFESDVMLPAPGQGALAIECRTEDAPSVAGSAEGADGVLAQALAAL
NDHDTRLAVTAERAVLARLEAGCAAPVGAYAFRKGSMLHLEAVVCAVDGTKTVREKKATD
GLTEVGATLLGIEVAELLLAAGAAEIADLAAS
>F3U168|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU045|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>Q474V1|hydroxymethylbilane synthase|EC 2.5.1.61|Cupriavidus pinatubonensis (strain JMP134 / LMG 1197)|TrEMBL
MHASAFPTSSTAVSSSLPHKLVIASRESRLAMWQAEYVRAALQQYYPACDVSILGMTTRG
DQILDRTLSKVGGKGLFVKELEFAMAEGRADLAVHSLKDVPMELPDGFALTAVMEREDPR
DALVSSTFASLEEMPAGTVVGTSSLRREAALRARYPHLVIKPLRGNLDTRLGKLDRGEYG
AIILAAAGLKRLGLGDRIRALIAPEASLPAAGQGALGIEILSTRPDVAAWLSPLNHQPTA
LAVTAERAVSRMLGGSCQVPLAAHARWVGDQLRLDAFVAMPDGSRQTRASAAGLVVDAAA
AEALGASAARDLLSQGAAEILAALADTPAPQDPA
>D2ABX4|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri serotype X (strain 2002017)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGEAPA
>Q11DF1|hydroxymethylbilane synthase|EC 2.5.1.61|Mesorhizobium sp. (strain BNC1)|TrEMBL
MQTDVIKIGTRGSALALAQAAETRARLMVAHGLPEDAFEIVVIRTSGDRIQDRPLSEAGG
KGLFTKEIEEALLEGRIDLAVHSSKDMPTFLPDGLELSAFLEREDVRDVFIGRAAKRLED
LPHGANLGTSSLRRQALALRLRPDLKVGVFRGNVQTRLRKLEDGAADGTLLALAGLKRLK
LEHVATELMDPVIFPPALGQGAICIESRTGDTRIAKLVEAIHHPATGFALSCERAFLAAL
DGSCRTPMAGLATVDGDRIAFSGMILTPDGREVHEIGGDGAAQDAAEIGRDAGRRIRQKA
GAGFFESWS
>H6N0K6|hydroxymethylbilane synthase|EC 2.5.1.61|Gordonia polyisoprenivorans (strain DSM 44266 / VH2)|TrEMBL
MSDTQNRAVIRVGTRGSLLARTQTQTIIDALIAAGHPAESVIIKTAGDASAAPVAEIGVG
VFTTALRNALHDGRIDVAVHSYKDLPTAPDPGLVIAAVPPREDPRDALVSKGGQVLGELP
PGSTIGTSAPRRAAQLKALGLGLEIRPLRGNLDSRLGKVASGELDAVVVARAGLVRIGRA
DEVTEAFDPVVLLPAPAQGALAVECRSDDAQLVRTLAELDDESTRASVDAERAVLAALEA
GCTAPVGAIAEVVESLDDDGRIFVELSLRAAVAAEDGSDVIRASVVGPVDRADQLGRDLA
AELLELGAGELVDSS
>H4MGZ3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC3B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E6PCY6|hydroxymethylbilane synthase|EC 2.5.1.61|mine drainage metagenome|TrEMBL
MLLGAGSVAARKARTFVEAGAKLSVVAPTIGEAMEALLAAHPDVRCERRAYREEDLAGAF
LCVAATDSPAVNEGAMRAARERGILTIDSTDPARGDATMPAVVRVGELTFSIDSGASTPA
FSKRIAREIAVHFDARYDAAARTLAIARSYVRETLSPSQRAVVMRALSELPLDDLAAMDR
NRIEDAVEATAATVLADGAAPSTSSAICATRGSALALWQSRHVAARLAQSGIATTMLALS
TVGDRDRSSALAAMGEQAIFVKELERALADGRADYAVHSAKDLPSALPAGMQLSAISSRE
DPRDVYCSERYATFAELPAGARVGTSSPRRRAQLYALRSDLAYVEIRGNVDTRLRKLREG
EYDAIVLAAAGLRRLSLHATHTVPFPVEQLLPAAGQGALAIETLRDAPLASALRAALNDE
RSERAVIAERAALRELGAGCTAPVGIHGAYEGGELLLRGRVSSTDGAPAIAAELRAPAAD
SAAAEELGCSLARALLARGAASLLPHGGPLAGRRIVLPRSVERTSRIAARLRALGAEVTE
LRAGEEPDEAPVDLLAIPSSGAAAVAAPWLLLWGERGVRPLVVAMGPESASAIERAGLPP
DGIAPIPEIDAFTACIVSLLASP
>H4GRJ0|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1242|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>I5L3K4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli PA33|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>F8GFD4|hydroxymethylbilane synthase|EC 2.5.1.61|Nitrosomonas sp. (strain Is79A3)|TrEMBL
MPNSLLYPQKIVIASRESLLAMWQAKFIQKCLGELYPQTEVSILGMTTRGDQILDQSLSK
IGGKGLFIKELEQALEDGRADIAVHSMKDMPMNVPEGFKLAAITEREDPRDAFVSNQYVN
LDTLPEGSVVGTSSLRRESQLRARFPYLQVQPLRGNVQTRLRKLDEGQYAAIILAAAGLK
RLGLSDRITALLNPEQSLPAVGQGALGIECRADRIDLVELMQPLHHQPTAFCVEAERALS
RVLGGSCQVPLGAFAEIIDGILELRGFVAQPDGKRIVSGALNGKPETGIAIGQQLAKKLI
TEGADEILATLVPAEGWK
>I1AQJ4|hydroxymethylbilane synthase|EC 2.5.1.61|Citreicella sp. 357|TrEMBL
MTDMLPTPDHPLKIGTRGSPLALAQAHETRARLMAAFDLPEAAFRVVVIRTSGDDRAMIA
ADRPLKEIGNKGLFTKEIEEQLLSGGIDIAVHSMKDMPTEQPAGLLLDCYLPREDVRDAF
IAPGAAGLADLAPGTVVGTSSLRRRAQLLNRRPDLRVVEFRGNLQTRLKKLHDGVAAATF
LAMAGLGRMGMTGGDVPMTPMSPGDMLPAVAQGAIGIERRINDDCTATLLAAIHHAPTAL
RLSAERSFLATLDGSCETPIAGLAELDGGTLRLRGEILSPDGATAWADEASGAESQGVEL
GAALARQLLGRAGPDFFAWRHP
>A8LDG6|hydroxymethylbilane synthase|EC 2.5.1.61|Frankia sp. (strain EAN1pec)|TrEMBL
MTVTRGPEARAHALLARRPLRLGTRRSALARAQSEKVAETLRTRLSRPVELVPIVTAGDQ
SQVAISQIGGTGVFVSALRDALLAGEIDLAVHSLKDLPTATPDGLVLAAVPRRADTRDVL
VSPSGRRLSELGPGARVGTGSPRRAAQLLALGHGFEVVPIRGNVDTRIKKAIDGEVDAVV
LAHAGLDRLDRLDAVTEIISPEVMLPAPGQGALAIECVRTPAGGGPAHDQTGPEAGRGFD
EGLAELLRFVLDDATSSVAVRAERAFLAGIEAGCTAPVGALAHVLPGTDARLVAGGDDAP
AVGEIRLRAVVAAPDGGRVLRRELTGSAVDPEALGQRLADELLSAGAHTLMGTS
>F4G3X8|hydroxymethylbilane synthase|EC 2.5.1.61|Alicycliphilus denitrificans (strain DSM 14773 / CIP 107495 / K601)|TrEMBL
MTTSSALPPIVIATRESQLALWQAEHVQALLAARGHSVSLLGMTTRGDQILDRTLSKVGG
KGLFVKELEVALEEGRADIAVHSLKDVPMELPDGFALACIMEREDPRDAFVSPHHASLDE
LPQGAVVGTSSLRRQVLLQALRPDLKIEPLRGNVQTRLRKLDEGQYAAIVLAAAGLKRLG
LHERIRSVFEPGQMLPAAGQGALGIEIRSQRQDLRDALAPLAHERTWLTVTAERAVSRAM
GGSCSMPLAAHGVWSGDTLRLQAAWGDVEGRLPLVRAEGSSRVATLDEADALGLAVAGRL
RAAGAVAAC
>D4W2E6|hydroxymethylbilane synthase|EC 2.5.1.61|Turicibacter sanguinis PC909|TrEMBL
MRVVVGTRGSKLALTQTQWVIDQLRKYHPEVEFEVKIIKTKGDLIQHVSLDKIGDKGLFV
REIEQQLLDKEIDIAVHSMKDMPSKLPKGLKFAAVPKREDPRDVLILKDGYKTLEDLPKG
AKIGTGSKRRKYQLLKYRPDLDILSIRGNIDTRIRKIEDENLDGIVLAAAGILRAGMSEM
ISSYIPVDIMVPAPAQGALAIQIREADLEIEALIESIKDVETEIRVAAERAFLAGVNGGC
HIPMGAYCELEGDKLKLTGLYGSENGNCLVRKCLEGGIESPIELGLEVAQFVLKEYDNYE
R
>C6PWV2|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium carboxidivorans P7|TrEMBL
MKLKIATRRSQLAQVQTETIMKILKENHNVEAEKLLVETTGDKILDVSLSKIGGKGLFIK
EIEVALLEDKADAAVHSMKDVPFDVPDMFDIVSIPPREDVRDAFVSMNGVHFKELKKGAK
IGTSSNRRAAQVKLLRPDLEIVPIRGNVQTRISKIEKENLDGIILAAAGLKRMNMENIIT
DYFDVNEMVPAVGQGALGIETKKNSVNEDIFKKMEDENTRICVEAERSFMRTLNGDCHST
IGAYAQINENTISIIGIFQVGDNLIKRDIAGNKEDYMELGYKLAKKIIEA
>E6MI69|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoramibacter alactolyticus ATCC 23263|TrEMBL
MKKIVVGSRGSKLAVTQTNWLIERLAAAHPDIAFELKIITTKGDRNQHQALDAIGDKGLF
TAELEAELLSGEIQMAVHSMKDMPSALPEGLCLTVPPMREDPADVLVTPHGAASLDDLPE
GAVIGSGSKRRVFQLKALRPDLQTVGIRGNIDTRIRKLFDEHLDGIVLAAAGMRRLNVYD
AADYHLVPLLPPAFVPAPAQGILAVEIREDNAEVKALMAAISDETARVQMAAERSFLTAL
DGDCHLPIGAYCEAAGDAITLYGLYGDEAGTRLVKGSAAGRAADAERLGAQLAEQLRKAL
EQPESEVEK
>E0UHD2|hydroxymethylbilane synthase|EC 2.5.1.61|Cyanothece sp. (strain PCC 7822)|TrEMBL
MVVSSPTRTVRIGSRKSQLALVQTYWVQGELQKHYPDRQFDVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMIDHQIDLAVHSLKDLPTNLPSGLILGCVTERVDPADGLVVNEKHKD
KQLDTLPEGAVIGTSSLRRLAQLRHHFPHLTFKDVRGNVNTRLSKLDAGEYDAIILAVAG
LTRLGMSDRIHQIIPSEISLHAVGQGALGIECRADDVEVLDLLKVLEHQATRDRCYAERA
FLRELEGGCQVPIGVNTSVEGDTLTLTGMVASLDGQKLIKDSITGKASDADQLGQELAIR
MRNAGAGEILAEIFAQINRE
>F1XIA7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. 1044|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>H7VY24|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli LMG 9853|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>F8DPR4|hydroxymethylbilane synthase|EC 2.5.1.61|Lactobacillus reuteri (strain ATCC 55730 / SD2112)|TrEMBL
MTDKVIVGSRKSKLAMAQTKLVIASLKELFPTTQFEIKNVITEGDRNQQASLAKIGGKGV
FVKEIEEELKNCTIDFAVHSLKDVMPVLPDELTLGAFPKRVSPFDCLVSRQEFTSLDALP
HGARIGTNSLRRQGQLLNVRPDLKIIPIRGNIDTRLKKIDTENLAGVVLAEAGLDRLSID
LSSYHQLSLKDIIVPAVGQGCLAIECRKADERVRKMLDQINDPQSAKCIHIEREFMRELG
GSCNFPIGGHAYLQDQQIVFDGLIASPNGEHLIKEVAVPANKPGVGKVVADQLLAKDNFG
IIEGD
>Q6MHU0|hydroxymethylbilane synthase|EC 2.5.1.61|Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)|TrEMBL
MRLRISARKSDLARLQAYMVGDALKEKNPQIEIDYRFRESLGDKNLTDPLWKIPEKGVFT
EDFFGELLRDETDLVVHSWKDLPTEHKSETVIAATLPRADQRDLLLVKKSHFDKIKTSKT
LKVFSSSPRREYNLTGFFKEHLPFGLQDVKFESVRGNMLTRVRKLIESPETDGLIVAKAA
FDRLFSATLPEFLEGQQQLRQYFNELNWVVLPLSVNPNAAAQGALAVEVLKSRQDLQDLL
QSIHHADTFHCSQKERDVLSSFGGGCHQKIGVAVLARPYGQITLLKGLTDAGQVLDKREL
KLNNPAPQFAAQDLWSSEVTAEREALKSYQIPAGTNGLFVARSEAWPADLKWSDFVWTAG
LKTWKNLSQKGIWVHGCAESLGEQEEALMDILAGKKLAWAKLSHEDGYASDQENMTLVPT
YTLKAQQEYQNLSGKKFYFWSSGSQFLKAAEQEPGILSQHHASGPGNTHKVIRSYLEENK
NYDPKRLHVFLDQEDWRKQCTK
>D5XEC8|hydroxymethylbilane synthase|EC 2.5.1.61|Thermincola potens (strain JR)|TrEMBL
MAREIVVGTRDSALAMWQTNWVVDNLRKLNPDYTFKIVSMKTQGDKILDVALAKIGDKGL
FTKELEFAMLRNEIDLAVHSMKDLPTVLPEGLKIGAICERHDPRDVLVARDGILLKDMPQ
GARIGTSSLRRTAQLLKYRPDLQIISLRGNLNTRMAKLERENLDGIILAAAGIERLGWAY
RITQRIPFEVCLPAVGQGSIGIEIREGDEEVSRIVDKLNHGPSAAAITAERAMLKKLEGG
CQIPIGALGRVEGDRLTLEGVVASLDGKELLRSRVEGPASEAASLGVALAEKLLDMGALE
ILKSVRQEFE
>I3ZGW1|hydroxymethylbilane synthase|EC 2.5.1.61|Terriglobus roseus DSM 18391|TrEMBL
MHLRIGSRGSRLALWQSNHIAAHLRALGHTAEVTIIRTTGDRLQDPAFAATVLGPDGRIP
ANIDGKGIFIKEIEEALEAGTIDLAVHSLKDLPTQLDARFTLAAIPERADPRDVLLVPEW
LQIHTLPANARIGTTSPRRIAQLRALNPEFQFVAIRGNIDTRIRKLGRGDCDALVLAAAG
LDRLGPRLLKPVELDPQHPEYGRTPHIECITHPEHDHLGEHFDAKGHEHGEELPGQADWI
RQRFDPEMMCPAPGQGALAIETRANDAATIAAIQPLDNAETRYAVEAERWLLHALGGGCA
LPVGALCTHADGGATLLATVVSPDGDAMANVMLFATPGESAENFGTRAANDLIAQGAREL
LAGEFATADAE
>F7XX68|hydroxymethylbilane synthase|EC 2.5.1.61|Moranella endobia (strain PCIT)|TrEMBL
MQDNLLRIATRKSPLALWQAGYVRDKLLRYHPHLQVEMVPLITRGDMILDTSLAKVGGKG
LYIHELERALLDHHADIAVHSMKDMTISFPDGLGIVILCEREDSRDAFVSKRYASIDTMP
SCAVIGTSSLRRQCQLRERRPDLQIQDLRGNVGTRLAKLDHGDFDSVVLAVAGLKRLGLE
NRIRQAIDPSDSLPAGGQGAVGIECRLDDTRTLTMLAPLHHQETALRVGAERAMNARLQG
GCQVPIGSYAVLDGEEVWLRALVGSPDGTNVIRCEGRAPLEQAEQLGLRLADDILDRGAR
AILSQIYQKNIQHHQ
>F3GZM1|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae Cit 7|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDQLP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDDVWLRGLVGDPSGSVLLHADARAPQTSAQALGVQVAEALLEQGAA
DILKAVYGEANNE
>E8CTB8|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. MB101509-0077|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>G7SS17|hydroxymethylbilane synthase|EC 2.5.1.61|Pasteurella multocida 36950|TrEMBL
MVVMMTRKSLRIATRQSPLALWQANYVKACLEKIHAGLVVELVPMVTKGDVILDTPLAKI
GGKGLFVKELEQALLKGEADIAVHSMKDVPMQFPAGLMLSTICQREDPRDAFVSNSYRTL
MELPAGAVVGTSSLRRQCQLKQLRPDLHIHSLRGNVGTRLAKLDNGDYDAIILAAAGLIR
LGQQQRITSLIDVTQCLPAAGQGAVGIECRQEAEIELLLAPLADPETTACVLAERAMNRH
LQGGCQVPIAGYAIIEEGQLFLRALVGEVDGSSILRAEGRSAVADAETLGIQVAEKLLQQ
GADKILQTLYSN
>Q16812|hydroxymethylbilane synthase|EC 2.5.1.61|Homo sapiens|TrEMBL
QQQVLLSPPSSLCFSGSLRRAEGRKQPKDESDSRGYPQEP
>E8QUP7|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain SouthAfrica7)|TrEMBL
MGKLVIGSRGSELALWQANYIKERLKKECFIESEIQIVKTTGDKILDAPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITQRADVRDTFLSAQFPDLMSLPKGA
KVGTTSLRRSMQLKCKRKDLDTESLRGNVQTRLKKLECGEFDAIVLAEAGLRRLNIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFSTLQKLNDEKSAFCCHLEREFIKGLNGGCQ
IPVGVHASLMGEKVKIQAILGLPNGEEVITKEKQGDKNKAFDLVQELLEAFLQNGAREIL
EKAQLF
>F4GUQ1|hydroxymethylbilane synthase|EC 2.5.1.61|Pusillimonas sp. (strain T7-7)|TrEMBL
MSEAPAKLVIATRASRLALWQAEHVRDRLQTLYPQCQVSLLTMTTRGDQILDRSLSKVGG
KGLFVKELETALLDGRADLAVHSLKDVPVDMQSPFALSVILERDDPRDAFVSNDYSSLDD
LPAGSVVGTSSLRREAQIRQRYPQLQVQPLRGNLDTRLGKLDRGDYAAIILASAGLRRLG
LEARIRSHLNPEQSLPAAGQGALGIEILESRSDMQTWLAPLSDPDTTACALAERAVSRVL
GGSCQVPLAAFAQRDGNTLMVRGLVAEPDGSRIIRAQVSGDVSQAEELGVRIANELLEEG
ARIILDRLLASGSAS
>F8KSU7|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter bizzozeronii (strain CIII-1)|TrEMBL
MKTLIIGSRGSALALWQASCVQGLLEQIGLKSTIRVVKTKGDKILDVPLAKIGGKGLFTK
ELETLLLNQEIDLAVHSLKDVPVEEIEPLSLAAITPRADPRDCFLSVQYSCLADLPQGAK
VGTTSLRRSMQLKRMRADLDTLSLRGNIQTRLERLKCGDFDAIVLACAGVQRLGLELPHQ
QPFSTEEMIPSMAQGALGVQMRRDHPYFDQIAQLNDPTSAFVCGLERCFVRQLGGGCQVP
LGVHASLTQDILQIQAIVGLSDGSRVLQESIQGQPSQADHLINTLVQNFLDQGAREILDQ
ATLLN
>E6XQR4|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella putrefaciens (strain 200)|TrEMBL
MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKG
LFVKELEVAILEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNIYKTISELP
LGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLS
GRIASFISAEQSLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEG
GCQVPIGAFAEINGDEMTLRGLVGNPDGSEIIEGIITGPKTEATQLGVALAEELLSKGAK
SILDAVYAKA
>H0HLF1|hydroxymethylbilane synthase|EC 2.5.1.61|Mesorhizobium alhagi CCNWXJ12-2|TrEMBL
MQTTAFKIGTRGSPLALAQALETRDRLRAAHGLPEDAFAIEVISTSGDRIQDRPLSEVGG
KGLFTKEIEEALLSGRIDIAVHSSKDMATALPDGLELSAFLPREDPRDAFIGKTAPSIVE
LPHGATVGSSSLRRQALILRMRPDLNVVMFRGNVQTRLRKLDEGVADGTILANAGLRRLG
LEHVATHLMPLATFPPAPGQGAICIESRVADERAASLVAAIDHRPTAQALACERAFLAVL
DGSCRTPIAGHAVVEGENLSFTGLILTPDGREAHEVSGSGRAEDAAAIGRATGQEVRAKA
GTRFFEGWA
>D9SYG6|hydroxymethylbilane synthase|EC 2.5.1.61|Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)|TrEMBL
MTAPLRLGTRGSALAMAQSGHVAEALTAATGRPVELVEVVTAGDRSTAPVQRLGVGVFVS
ALRDALTAGEIDFAVHSYKDLPTAAAPGLHVAAVPPRQDPRDALVATNGRTLAELPPGAR
VGTGALRRIAQLHALGMQLEVSPIRGNVDTRLGRVLGPDADLDAVVLARAGLNRIGRADV
ITETLDPMLMLPAPAQGALAVECRADDQDVIELLALLDHAPSRAAITAERALLATLEAGC
SAPVAAYAVLAEGEPTDEGDVNQEIYLRGAVISPDGTRDLRLSRTGTPADAAEIGKALAA
ELLELGADSILGQDAQAGPGTQQLGSTE
>Q2IKS9|hydroxymethylbilane synthase|EC 2.5.1.61|Anaeromyxobacter dehalogenans (strain 2CP-C)|TrEMBL
MIRIATRRSPLAKWQANHVSQLLRDREPGLEVRLHELVTRGDKILEVPLADVGGKGLFVK
EIEDALLNRDAEVAVHSMKDLPAVLAPGLVLASVPQREDPRDALCSPRWKTLAALPKGAR
VGTSSLRRSAQLKALRPDLQMEVVRGNVETRLRKASEGLDAVVLAYAGLRRLGLAEHATY
VFPPEEMLPAVAQGALALEARADDAPTLKRLAALEDPETRVRIEAERGFLARIEGGCQVP
IAGHATLAGGKITIRALVASLDGTRVIRGERTGAYAEARALGESLAEELLSRGADQILRE
TEGKAPGLAAPKRG
>E0P7N8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus ATCC BAA-39|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H8ITG9|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium intracellulare (strain ATCC 13950 / DSM 43223 / JCM 6384 / NCTC 13025 / 3600)|TrEMBL
MIRIGTRGSLLATTQAGVVRDALIALGHPAELVTITTAGDRSSGPIESLGVGVFTTALRE
AMEEGRVDAAVHSHKDLPTADDPRFAVAAIPVRNDPRDAVVARDGLVLGELPPGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDTRLAAVLAELDDADTRASVTAERTLLAELEAGCSAPVGA
IAEVVESIDEEGRIFEELSLRGCVAALDGSDVIRASGIGTPGRARELGLSVAAELFELGA
RELMRGARQDPTRGN
>G9UJF9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 29N|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>Q0SF27|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus sp. (strain RHA1)|TrEMBL
MSAVGTRTLRIGTRGSELATTQAGTVRDALISAGHDAELVIIKTKGDQSMESVEKIGVGV
FTAELREALADGRVDVAVHSYKDLPTAPDERFTIAAIPPREDPRDALVARDGLVLGELPA
GSKVGTSAPRRTSQLRALGLGLDIRPLRGNLQRRLGKVESGELDAVVLARAGLARIGRLD
LITESIEPVQMLPAPAQGALAVECLSANTALVAILSELDDPNSRAAVTAERALLAELEAG
CTAPVGAIAEVVESLDDDGRIFDELSVRGCAAAIDGSDVIRTGAVGSPENAEELGRSVAR
ELLELGARELMNVTEAGDADV
>D7DRN4|hydroxymethylbilane synthase|EC 2.5.1.61|Methanococcus voltae (strain ATCC BAA-1334 / A3)|TrEMBL
MTLTIRIGTRGSKLAMVQTNYVNEILNKEIQTNKDIDTEIIKIKTVGDKDQNKKLVDLGL
GVFTKEIDKSMLLNETDIAVHSLKDVPTLWSDELIIKAVPPRESYNDLLIWKKNRKLNVF
QDDIVVGTSSIRRAAFLEIRYPNLDVKLLRGNVQTRLKKLDDEEYDAIIMAEAGLNRLNI
NLEDYNYEVLNMLPAPAQGAIGIATRKADEEINEIVELLDDKKTHLEVLAERNALKEYGG
GCQAPFGALAVYDEEENVLSLTCDLVFEANGKNVLVSKEGFVYCDIDDFEKAADLGKNLG
KLLKSYENEVLGINNE
>D3DIR7|hydroxymethylbilane synthase|EC 2.5.1.61|Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)|TrEMBL
MRLRIGTRKSKLALWQANFVKEKLEKMGHQVDLVHITTSGDKILDVPLAKIGGKGLFVKE
IEEALMKKEIDLAVHSLKDVPMNLPEGLKIGAVTERENPFDVLISKDHLPLEELPSNAKV
GTSSLRRQVQIKRRRGDLRVEMLRGNVDTRIRKLDEGLYHAVILAYAGVKRMGLEDRITQ
VLEDFIPAVGQGSLAIEIRQDDSAVEEIVSCFDHYESRLRAECERAFLRELQGGCQVPIG
AYSWIEGDTIFIKGFVSDLEGIKFIEGMRSGEAKEAQQIGKSLAHDLLREGADQILKEVY
GWTP
>C9TVM6|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella pinnipedialis B2/94|TrEMBL
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>Q1EPC8|hydroxymethylbilane synthase|EC 2.5.1.61|Musa acuminata|TrEMBL
MRHRAPLPPRPADLPRAPAAAGVPRRRGGRLAGQGPPNPDRDAWKVIKFDPFLRDSDLAL
AQARETRDKLKAAHSELAEEGAVEIIIIKTTGDMILDKPLADIGGKGLFTKEIDDALLQG
RIDIAVHSMKDVPTYLPEGTILPCNLPASLRRQSQILCRYPSLKVVNLRGNVQTRLTKLK
NGDVHATLLALAGLKRLNMVENVTSILSMEEMLPAVAQGAIGIACRSNDNKMMEYLSSLN
HEDTRSAVACEREFLTVLDGNCRTPIAAYAHRDKDGSCSFRGLLASPDGSKVYETTRIGP
YSFDDMVEMGKDAGHELKAKAGPGFYDC
>D5RAQ3|hydroxymethylbilane synthase|EC 2.5.1.61|Fusobacterium nucleatum subsp. nucleatum ATCC 23726|TrEMBL
MKKNIIIGSRGSILALAQANLVKDRLQGNYPNLSFEIKEIVTSGDKDLKSNWENSDISLK
SFFTKEIEQKLLDGEIDIAVHSMKDMPAISPKGLICGAIPDREDPRDVLVSKNGFLVTLP
QGAKVGTSSLRRAMNLKAVRPDFEIKHLRGNIHTRLKKLETEDYDAIVLAAAGLKRTGLA
DKITEYLNGEVFPPAPAQGVLYIQCRENDEEIKKFLKSIHNETVAKIVEIEREFSKIFDG
GCHTPMGCYSQINGDKIKFTAVYSDEGKQIRAVVEDDLAKGKEIAHMVAEEIKNKIVK
>H7VTK4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 151-9|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>I0ZBX3|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori NCTC 11637 = CCUG 17874|TrEMBL
MGKLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEKSAFCCRLEREFIKGLNGGCQ
IPVGVHASLMGDRVKIQAVLGLPNGKEVITKEKQGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>F2QP90|hydroxymethylbilane synthase|EC 2.5.1.61|Pichia pastoris (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)|TrEMBL
MLSPVSQNYQSSTTLLTTGNTAHSAMLESYQNMNQIEQSGPIDCSSLKLGSRKSALAIIQ
AEIVRQLILKEYPELETKLVSVSTLGDQVQNKALFTFGGKSLWTKELEMLLLESVGGFDQ
IDMIVHSLKDMPTHLPDEFELGCIIEREDPRDALVVQDGLSYKSLADLPEGAVVGTSSVR
RSAQLLKNFPHLKFKSVRGNLQTRLRKLDDPDSEYCCLLLAAAGLIRTGLQHRISMYLND
DVMYHSVGQGALGVEIRKGDQFMKNICEKIGHRTTTLRCLAERALLRYLEGGCSVPIGVS
TIYSEDTKELTMNSLVVSCNGRDSVTESMTEVVTTEEQAEDFGERLAQKLIDQGAKRILD
EINFNKIKEIKEEGLH
>F9SGY3|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio splendidus ATCC 33789|TrEMBL
MTNSAPIRIATRKSPLALWQAYFVRDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQLLEYRPDLIIKELRGNVGTRLGKLDDGQYDAIVLAAAGLKRLKL
EDRIRSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNDKDTADRVLCERAMNLTLE
GGCQVPIGSYSLLDGDNIWLRALVGEPDGSKMIRGEISGPREEAEALGVTLANQLLDDGA
REILTKLYADQE
>H2H954|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium diphtheriae (strain HC01)|TrEMBL
MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREE
LHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAP
RRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQ
DFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHA
TLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
>A5V7N0|hydroxymethylbilane synthase|EC 2.5.1.61|Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)|TrEMBL
MTASLSRPLRLGTRGSPLALTQARMVIAALRAAHGWDETAVEIVAIKTSGDRIQDRALAE
VGGKALWTKELDIALADGTIDFAVHSMKDVETIRPAAIVIAAMLPRADVRDRLIGAASLA
ALPQGARVGTSSPRRSAQVRRARPDVGIVLFRGNVDTRLGKLAAGEAEATLLAGAGLIRL
GRDEIGHPIPIEEMLPAPAQAAVGIETLAERTDVRALLGAIDDAPTNASVSAERALLAAL
GADCRSPVAALAVRSGAGLLLRAEIMTEDGSEHRSGEAMLFETGDAAALAHRLLDGASPR
LRALFTGA
>I4S2C4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 541-15|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B5W421|hydroxymethylbilane synthase|EC 2.5.1.61|Arthrospira maxima CS-328|TrEMBL
MTTSVSAQTRTIRIASRKSQLALVQTYWVQEELQKRFPDIKFEVHTMSTQGDKILDVALA
KIGDKGLFTKELEVGMLNHDTDMAVHSLKDLPTNLPEGLMLGCVTEREDPADALVVHENH
RDKQLDTLPPGAVVGTSSLRRLAQLRHNFPHLEFKDIRGNLNTRLQKLDEGQYDAIILAV
AGLKRLGMADRIHQVIPAEISLHAVGQGALGLECREGDTEIFEVVKALEHTVTAQRCHSE
RAFLRELEGGCQVPIGVNTMVEGDRLTLTGMVASLDGKRLIKDTVTGQASDAEQLGIQLA
HKLKQQGAEEILAEIFAEVQRS
>G2I2R9|hydroxymethylbilane synthase|EC 2.5.1.61|Gluconacetobacter xylinus (strain NBRC 3288 / BCRC 11682 / LMG 1693)|TrEMBL
MESAKPSAPFPSSALQKVAAEAAARQRKEATHPEPHRRQLPLKVGTRASPLALVQTRAFL
TVLTRFCPVLRDMGAFQEHQISTTGDQVLNRKLAEIGGKGLFAKEIHEALLDGRIDFAVH
SLKDLETTLPPGLVLACTLKREDARDVLILGPGCGEPDPMDPYAVLPQGALVGCASVRRQ
AQMLHVRPDLKFGLLRGNVQTRLDKLAARQCDATLLAYAGLRRLGMEDRADVILDPTIMV
PAAGQGIVGVTVRESDVELRELLSAIEDYEARAVATAERALLAELDGSCRTPIGGYARLI
PVVAGGAPELHLTGLVAREDGSFLLKRSISGSPADAARLGRDLGRSLRADSPADIFVEEK
>H0F970|hydroxymethylbilane synthase|EC 2.5.1.61|Achromobacter arsenitoxydans SY8|TrEMBL
MRDRLRTLYPACAVELLTLTTRGDQILDRTLSKVGGKGLFVKELENALLDGRADLAVHSL
KDVPVDLQAPFELCAVLDRADPRDAFVSNHYATLAELPAGAVVGTSSLRRESQIRARYPA
LVVKPLRGNLDTRLGKLDKGDYDAIVLAAAGLERLGLGARIRALLDPADSLPAAGQGALG
IEIRDDRSDMRAWLAPLVSADTTACVLAERAVSRKLGGSCQVPLAAYAQISDGALSLRAL
VASPDGVRMVHAARSGPASEAEAIGEAAASELLDAGAETILRELLQAPGPG
>H7Z4U8|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 53161|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESILRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>E8WTA8|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter sp. (strain M18)|TrEMBL
MALKELRIGTRASQLALWQANWVKSELEKRYPDMTVTLKKIKTIGDKILDVPLAQVGGKG
LFVKEIEEAMLRGEIDIAVHSMKDVPTEFPEGLGLYCITEREDPRDAVISRGVKFADLPQ
GARIGTSALRRQAQLLKVRPDLEMVIIRGNVQTRMDKLETEGLDAVILAAAGLNRLGFAD
QITELLPTDLSLPAIGQGALGIECSLSNEEVKDAISFFNHPDTSRAVRAERALLWRCEGG
CQVPIAAYGEVTGDQLKLTGFIASVDGKVSVKGVVTGPADECEKLGVKLAEQLLSDGGHA
ILAEVYQREVSREKEIPV
>H7XUQ1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 60004|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>D6U9P2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus ATCC 51811|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>B2UA05|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia pickettii (strain 12J)|TrEMBL
MSSNARPTSRQSQLATTPAAQAPTKLVIASRESRLALWQAEHVRAALQKYYPACDVSILG
MTTRGDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMELPEGFALSAILE
REDPRDAFISNDYADLASLPAGAVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLGKLD
RGDYAAIILAAAGLKRLGLVDRIRSTIAPEESLPAAGQGALGIEIRADRADVRACLAPLH
DEPTALAVTAERAVSRILGGSCQVPLASFAQWSDGGTLRLRAFVASQDGTRKLAADGEAT
PSTLAEADALGVRVAQQMLAGGARDILAMLGADAPPAT
>A5XIL9|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei FMH|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>Q5FA83|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDRILDRTLSKVGGKG
LFVKELEQSLQDGRADLAVHSIKDVPMDLPEGFALAAISERANPFDAFVSNRYARLEEMP
EGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
ERIRMILSESDSLPAAGQGALGIEIATHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLILRGLVGHPDGSIVLQADAQAPAGYADALGRAVAKKLADDGAQ
ELIGAVLNTEN
>Q4E9N3|hydroxymethylbilane synthase|EC 2.5.1.61|Wolbachia endosymbiont of Drosophila ananassae|TrEMBL
MLVKIGTRGSKLAVVQALEAKQKLLDSFPNLSIEIVKIKTSGDKYANANLAEIGGKGLFI
KEIEAELLENNIDMAVHSLKDVPAFFSWGLTIPCVLERLSPCDAFISHKHNSLESLPQQA
TIATSAIRRKVQLLNFRPDLNIVPLRGNVTTRLQNQSFDGIILAEAGLIRLEKHHLITEV
LPPKVMLSAVGQGAICIQCRRNDVKIIDLLEKINNNMSFIGVKSERSFMKTVNGSCFTPL
AALAEYVSENMLYLSLYVGRWKKYILH
>E1SKN3|hydroxymethylbilane synthase|EC 2.5.1.61|Pantoea vagans (strain C9-1)|TrEMBL
MVNSMLDKIFRIATRQSPLALWQAHYVQQRLMSAHPGLRVELVPMVTKGDIILDTPLAKV
GGKGLFVKELELAMQDGRADMAVHSMKDVPVSFPEGLGLVTICERDDPRDAFVSHHYDSI
DALPQGAVVGTSSLRRQCQISARRPDLVIRSLRGNVGTRLGKLDAGEYDAIILAVAGLKR
LGMQDRIRQAMPAEVSLPAVGQGAVGIECRLNDSVLIDLLRALNHDDTEVCVRAERAMNT
RLEGGCQVPIGSFAVLEGDELWLRGMVGAPDGRVMVSGERRGPRAQAEQMGISLADELLN
GGAREILKEVYQGQPPA
>G4ID39|hydroxymethylbilane synthase|EC 2.5.1.61|Halobacterium sp. DL1|TrEMBL
MSNEPMRLASRGSDLALRQAGEVKSTLADRRHEVDVVEVETKGDRVTDALISELGKTGAF
VHALDQEVLEGNVDAAVHSMKDVPTEMPDDLFVAAVPRRGNPADVLVTPNGATLDELPAG
SVVGTASLRRGAQVQARRPDLTVEPIRGNVDTRVEKLLAPALQAEHEARTEAEKERKAED
GRQQDNGDYSESIRGGIQNVQENRDDEEDGSRKNAEYDQTVEEWFESLSPLQQSAMGREV
ETEYDAVVLARIGLERTGLIHHVGIAELSKESHVPSAGQGALCVTARRDSDVVDDLRDAL
DHVRSRVETTVERVVLEELGGGCIAPIGIYALVKGEIVRTSVQVFSRDGSERVAETRDLD
AENYASEAREFAADLRERGAADLVEAARRED
>D1GMT0|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain TW20 / 0582)|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>B3PF72|hydroxymethylbilane synthase|EC 2.5.1.61|Cellvibrio japonicus (strain Ueda107)|TrEMBL
MSVSLSLLRIATRKSLLALWQADYVKTELERHHPGLRVELVPLTSRGDKILDVPLAKVGG
KGLFVKELEQALLAGAADIAVHSMKDVPMEFPDGLGLAVICPREDARDAFVSNRFASLDD
LPAGAVVGTSSLRRQCQLLARRPDLQVKFLRGNVQTRLQKLDDGEYDAIILAAAGLIRLE
LQARIRSLIAPEVSLPAGGQGAVGIECRMQDQATLALLQPLHHQPTAEQVLAERAMNRRL
QGGCQVPIACYALQQGGELWLRGLVGAPDGSQMLFDEIRGPVAEGEQMGIQLAERLLAAG
ADSILAQVYGEADEE
>F8BS60|hydroxymethylbilane synthase|EC 2.5.1.61|Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)|TrEMBL
MRIGTRKSVMALAQTSEIARQLTAADPALDVEIVKFETTGDQDQTGKLLDLGGKGGAFVA
QIRDAVREGRLEAAMHSLKDMPGNEDTPGLVIGATLTRDPPTDALVVRHGVTLADLRRTG
GKGFKIGTNAVRRAAYVRRLFPECEIIHFRGAADTRIRKLDNGEKQRLPEGGEVGPADAL
VMAQAGLERVGCADRIAHCFSPDEILPAVGQGIVAVECAASDWCTLARLAQIDDPVSRCC
AAAEREVLWVLNGHCNSPIAGYAIVEGDDVLLKAAVLDEANDHFIEVTRRGPASRPRELG
RAVAFELLAKGAADVIARTRPVSAH
>G0J269|hydroxymethylbilane synthase|EC 2.5.1.61|Cyclobacterium marinum (strain ATCC 25205 / DSM 745)|TrEMBL
MKSIRIGTRGSKLALYQANYVADLLNKSGINTTIVTIETKGDKVLDVSISKIGSKGVFTE
ELETKLAVGEIDIAVHSAKDLPSRLPEGFETIAFTEREKVNDIIISHKDDFPDLNDPSKP
IVLGTSATRRVATLKYFYPHIKTVDVRGNLQTRVSKMENGLCDGLLLAYAGVHRMGYDQL
IKKELPLSEFIPAVGQGSIGVEIHSGMDPDLKKLLKAAINHPKSAACLTAERSFLSVLEG
GCSIPAFALAHWEGDRLILEGGLMQIDGKERLFSSHSSTEAEASLLGKKLAEDIKSQGGD
LLLKEIKQRLNG
>D2SHH5|hydroxymethylbilane synthase|EC 2.5.1.61|Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20)|TrEMBL
MTATTIGTLRLGTRASQLATTQSQAVADAITAASGVPVELVHISTEGDRSSVAIAQLGGT
GVFVTAIRQALLEGTVDVAVHSYKDLPTLPEPGLTIAAVPPREDPRDALVARDGLTLGEL
PAGARVGTGAPRRVAQLRALGLGLEVVPIRGNVDTRMARVVPGDLDAVVLARAGLSRLGR
LSAVTETLDPLQVLPAPAQGALAVECRGNDERTRQLLAALDDAATRACVVAERTTLAALE
AGCSAPVAAYAEVAEGEDGPELFLRASVTALDGSDGVRGSITGPPPEAERLGRELAAELL
DRGAAELMAASR
>D1BFI8|hydroxymethylbilane synthase|EC 2.5.1.61|Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)|TrEMBL
MTGHPALRIGTRSSLLALTQTGTVADDLRRLTGRPVEIVPVTTDGDVLTGSLSQMGGTGV
FVTALRAALLDDRCDVAVHSLKDLPTAGVLGLQHVTPVRQDPRDALCSRAGHRLADLPHG
ARVGTGSPRRAAQLRLVRPDLDVVDIRGNIDTRLGRVHPETGDLDAVVLAAAGLNRIGRE
HAITELISVTDMAPAPGQGALAVETRSSLLEEDPVVARAFDQLDDPATSLSVLAERALLA
RLEAGCAAPVGTHATVSDGLLTLHAVVARPDGSEQLRHNQSTEVADTSTAEAVALGEAVA
DHFLALGAASFI
>I0TTN1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-K|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>E5ZIW1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 327|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPRGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>B9CUG7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus capitis SK14|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKKVDPDLDIEIKEIVTKGDQIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSIIPEGLTLGCIPDREVPFDAYISKNHTPLSELTEG
SIVGTSSLRRGAQILSKYPHLEIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDD
IVTTYLDKDVLLPAIGQGALGIECRSDDKELLELLKKVHNQDVAQCVTAERTFLSEMDGS
CQVPIGGYATIDGDKQIEFTGLIMTPDGKERYEHTAKGLDPVELGQEVSRVLKEQGAYEI
IRKLNEENN
>F2JDB9|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori 2018|TrEMBL
MGKLVIGSRGSELALWQANHIKERLKKECSMESEIRIVKTKGDKILDTPLSKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTVLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKFKRKDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLNVQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHANLMGDEVKIQAVLGLPNGKEVITKEKQGDKNKAFDLVRELLEEFLQSGAKEIL
EKAQLF
>G2BG64|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli G58-1|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E6QGX0|hydroxymethylbilane synthase|EC 2.5.1.61|mine drainage metagenome|TrEMBL
MIHSSPDHHQSRRADMPHSLRIGTRASPLAVWQAEHVRAELLRLHPGMAVEIITMTTSGD
VLLDAPLHALGGKGLFVKEIEDALQQRRVDVAVHSMKDVPALQPDGLEIVAIMAREDVRD
AFVSNTFLHPDALPEGARVGSSSLRRRAQLLERYPHLRVEDLRGNVATRLRRLDEGHYDA
IILAAAGLRRLGLPDRITHLLDIDRSLPAVGQGAIGIEARSDDRRTRELLASLADADTQN
CVLAERSMNQVLGGDCRLPVAALARWQGPQMLLRGLVATPDGRRVLHAEAKGSDPVALGM
AVAAALVAQGAAEIIEDVRNA
>Q5PAL0|hydroxymethylbilane synthase|EC 2.5.1.61|Anaplasma marginale (strain St. Maries)|TrEMBL
MYAPVVRLGTRGSTLALIQAEEVKAAIAAHFPEVRVDVTKIKTSGDIKVDRPLCDIGGKG
LFIKEIEEALLANKIDIAVHSAKDVPGFYSENLDMPCVLKRRSPMDVFISVKYKSLNSLP
AGAKIGTSSIRRKVQLLAFRPDLEITPMRGNVDTRIAKVQSGECDGIVLAEAGVDRISAR
AKITEVLHPDVMLGAVGQGAICVQCRKSDEGIVRMLAKLNDHESFTAVLAERSFMKAVNG
SCHTPLAAMARYVDSGLMSMKCMLAHDSRTMVSAERTFPERDAESVGFEMGVMLKDELRL
RGV
>E7TCR9|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri CDC 796-83|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E0QGM3|hydroxymethylbilane synthase|EC 2.5.1.61|Eubacterium yurii subsp. margaretiae ATCC 43715|TrEMBL
MKMQTVRIAGRKSKLALVQTQRVIDLLKQKYKDVNFEIVTVETLGDKNLKEKLSEIGTKG
LFTFEIEQMLLNGSVDMAVHSLKDMPTDFIRDLKIGAYIKRESNKDVIVFNKDYKSVKDL
PKNAKIGTSSLRREVQIKKLGKDFEVANIRGNIHTRLKRMKDENFDAIILAKVALTRLNL
QDELVFEELPFVSAAGQGCICVQVKKDNKKIEKMLEFLNDAETQSCVMAEREFLHTIGGG
CHTPVGAYCEKIGQIYRIYAFVSSLDGKKYLSCEIKSKDTENLGKQTAQRLIAKGADKIV
K
>D0J464|hydroxymethylbilane synthase|EC 2.5.1.61|Comamonas testosteroni (strain CNB-2)|TrEMBL
MKFSASSPTSIVIATRESQLAMWQAEHVQAILRGRGHSVDLLGMTTKGDQILDRALSKVG
GKGLFVKELEVALEEGRADLAVHSLKDVPMELPEGFVLACVMTREDPRDAFVSNRYASLD
ELPQGAVVGTSSLRRQALLQALRPDLKIEALRGNVNTRLRKLDEGQYDAIVLAAAGLMRL
EMSERIRARFDPAQMLPAAGQGALGIEVRADRQDIIDALAPLAHMPTWLTVTAERAVSRC
MGGSCSMPLAAYGRFEGDTLHMDAAWGDMEGSKGLVRVQASAQVTDFASANALGEQLAAQ
LQAAGAVPAAPKQD
>I3AMI0|hydroxymethylbilane synthase|EC 2.5.1.61|Serratia plymuthica PRI-2C|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQQRLMASHPGLQVDLVPMVTKGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPIDFPAGLGLVTICERDDPRDAFVSNRFASFDQLP
QGSVVGTSSLRRQCQLRERRPDLIVRDLRGNVGTRLAKLDNGDYDAIILAVAGLKRLGLE
QRIRSPLSPEECLPAVGQGAVGIECRLDDDATRALLAPLNHTATDIRVRAERAMNTRLEG
GCQVPIGSYAELEGDNLWLRALVGSPDGSQMVRGERRGPAALAEQMGVELAEELLARGAR
DILHDVYQGNPPA
>I3D8Y3|hydroxymethylbilane synthase|EC 2.5.1.61|Pasteurella bettyae CCUG 2042|TrEMBL
MNEKQSLKIATRQSPLALWQANYVKDRLTNLYPDLQVELVTMVTKGDVILDTPLAKIGGK
GLFVKELEHALLNHQADIAVHSMKDVPMQFPAGLELSVICKREDPRDALVSNKYHHLDEL
PKGSIVGTSSLRRQCQLKKLRPDLEIRSLRGNVGTRLNKLDNGEYDAIILASAGLIRLGL
SERIASFIEIEQSLPAAGQGAVGIESRADDSRVKKLLAPLADQETTICVLAERAMNNHLQ
GGCQVPIGGFAQIQNNQVYLRALVGALDGSQIIRAEGKSAVENAENLGVQIAEQLLAQGA
DKILEEVYQG
>G4HHW4|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus lactis 154|TrEMBL
MRTIVVGSRQSALALTQTGQVIDDLKRLAKEHGLEYEFTVKKIVTKGDRIVDVTLSKVGG
KGLFVKEIEQAMLDGEIDMAVHSMKDMPSVLPEGLVSGAVPKRKDPRDCLISMEGSTLDD
LPQGAKVGTSSLRRSSQLKAYRPDLKIDWIRGNIDSRIRKLESGEFQAIILATAGLQRMG
WEDRITSYLPIDISLPAVGQGALGIECRENDAELLHLLSLYNDEVTARTVSAERRFLSEL
NGGCQVPIGAYAVIKEDSGDSRGAQNIIQLTGMVGSPDGEIILKETAEGTDPESLGIEVA
EKLKAKGAEKILAQVRG
>C2DYA1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 83972|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>I2JFU0|hydroxymethylbilane synthase|EC 2.5.1.61|gamma proteobacterium BDW918|TrEMBL
MSDNIIRIATRESLLALWQAEFIKAELQAAHPGLQVELLGMTTRGDQLLDSPLSKIGGKA
LFVKELEQALLEGRADIAVHSMKDVPMEFPAGLGLAIICEREDPRDAFVSNHFSAVEALP
QGARVGTSSLRRECQLRAQRPDLQISSLRGNVQTRLRKLDEGEFDAIVLASAGLIRLKLE
ARIASYMSVETSLPACGQGAVGVETRIDDDRVNALLKPLHNSVSATQVMAERAMNRRLEG
GCQVPIAGYAIADPSNPDQLWLRALVGEPSGGKILTAEARGPRSQAEALGVAVAEDLLAQ
GAGAILQAVYGNSKPA
>I3YFF6|hydroxymethylbilane synthase|EC 2.5.1.61|Thiocystis violascens DSM 198|TrEMBL
MSNSIRIATRKSPLALWQAEHVAALLKGLYPDLAIEIIGMSTKGDRILDAPLAKVGGKGL
FVKELEQGMLEGTADIAVHSLKDVPVEFPEGLHLAVVMEREDPRDAFVSNVYPDLDALPQ
GACVGTSSLRRQCQLADRRPDLRIEPLRGNVNTRLAKLDAGEYDAIILAAAGLMRLGFES
RIRARIEPAFSLPAIGQGAIGIECRQNDPRINDLIAPLHHPDTADRVLAERAMNARLHGG
CQVPIAGHATLDGERLLLRGLVGSPDGKLVLRAEFAGPRAEFDHIGTQVADDLLAQGAGA
ILSALQE
>E1RVU3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain UM146)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>A0B884|hydroxymethylbilane synthase|EC 2.5.1.61|Methanosaeta thermophila (strain DSM 6194 / PT)|TrEMBL
MTVRTSGDLFLDRPLHMISGQGLFVREIDERMLSGEIDLAVHSMKDLPSKRPERLRIAAI
MKRDSPCDILLTKDGSGLDDLKSGAVIGTSSMRRAAQLRRARPDLVVRSLRGNLQTRLRK
LHAGEYDGIVIAEAGVQRMGYHLGYKVLDPGFFVPSPNQGTIAVVSVAGTEGDALASLID
HRPSREETMVERRIMEVVGGGCLVPMAVFARHLGDRIHVTAEILSKDGERFVRLEDTVPR
DGLESAERIGRRLLEMGGDELVREAVEIER
>B2GL24|hydroxymethylbilane synthase|EC 2.5.1.61|Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)|TrEMBL
MSGAVFTVGTRGSQLAMTQSRWAAEAVSRAGGIDHELVTVRTEGDVLTGPLSQMGGTGVF
ATALRSQVLDGRVDLAVHSLKDLPTAPVEGLRIVALPEREDPRDALCARDGLTLAELPEG
AAVGTGSPRRVAQLRALRPDLRIVDIRGNVGTRLNRVAPADPGDLDAVVLAASGLKRLGL
EGRITEYLDPHVMLPAPGQGALALEVSARLDPSGALMRGLEAVDHLPTRLAVTAERAVLA
QLEAGCAAPVGTFARVAGDVLELDVVVANPDGSEVMRRSESVPAPSVEEAEAFGRRIADD
LLAQGADRLARLSL
>E0NAR0|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis ATCC 13091|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDRTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>F5SR95|hydroxymethylbilane synthase|EC 2.5.1.61|Psychrobacter sp. 1501|TrEMBL
MTTSAHTTTLKTLNIATRKSPLAMWQAEHIKSRLESLYPELEVNLVTMVTQGDKILDTPL
AKIGGKGLFVKELEQALYDGRADIAVHSLKDVPMQLPEGLILGTYCKRETPTDAFVSNNY
DKLEDLPEGAVVGTASLRRQCQIKAFRPDLQIKSLRGNVQTRLSKLDAGEYDAIILATSG
LKRVELSERIKQEIDIDISLPAVGQGALAIECRSDDEAVLELLKPLNDGQARIRLKAERA
LNRRLEGGCQVPIAAYAVIEKDSEPSDQQIFQKTLWLRGRVGSEDGTTLLKAEKRIELSG
DQAAREAQAEQLGIEVADELLSLGADSILAAIYSDKKDQ
>A3V758|hydroxymethylbilane synthase|EC 2.5.1.61|Loktanella vestfoldensis SKA53|TrEMBL
MIESAGRHCCDAKTDVMQGFGRALFGAMFMPAG
>C6CGK2|hydroxymethylbilane synthase|EC 2.5.1.61|Dickeya zeae (strain Ech1591)|TrEMBL
MDKKDQYGTSMVDTILRIATRQSPLALWQAHFVKQRLEDCHPGLQVELVPMVTRGDVLLD
TPLAKVGGKGLFVKELELALLENRADIAVHSMKDVPVEFPEGLGLVTICERDDPRDAFVS
NHYATLDDLPEGACVGTSSLRRQCQLRAYRPDLVVRDLRGNVGTRLSKLDNGDYDAIILA
VAGLKRLGLAHRIRTALSPEQSLPAVGQGAVGVECRLDDARTRALLAPLNHEDTATRVLA
ERAMNTRLEGGCQVPIGSYAELQDETLYLRALVGAPDGSRIIYAERRGSRQDAETLGIAL
ADELLERGARDILQSVYGGASS
>E0NW13|hydroxymethylbilane synthase|EC 2.5.1.61|Selenomonas sp. oral taxon 149 str. 67H29BP|TrEMBL
MNSGTITIGTRASKLALWQANYVAEAIKKEHPSCCVELRELTTKGDRILDAPLAKIGGKG
LFTKELEQAMLDDAVDLAVHSLKDMPTEIPDGLVIGAITTRLDPGDAFVSAHYAAVEDLP
VGARVGTSSLRRRAQLLAVRPDLTICDLRGNVNTRLAKLDAGEFDAIVLAAAGLKRLGFE
RRIRTILPRSVMLPAVGQGALAIECRAGDAAILSAIEFLRDAGMTTAAQAERAFLRRVEG
GCQIPVGVYAEVDANGQISIDAMIASVDGQRICRSDAHGAGEQAEALGTALAEELLDAGG
REILKEIGITA
>H3UMP5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU057|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>G0HHX4|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium variabile (strain DSM 44702 / JCM 12073 / NCIMB 30131)|TrEMBL
MTRTLLIGTRASALASTQTGMVRDALVDNGATADLHFVHTPGDASQKAQTPVSRIGVGVF
TETLRNALAAGECDVAVHSFKDLPTAPDPRFIAVVPPRVDPREVLVSHGNLTLRELPTGA
KIGTGAPRRVSQIRAVRPDVECISIRGNIDTRMGRAGDGTTSTVVEGGPGDLAAVVLARA
GLERVGHLDHAAETVAVTDIMPAPAQGALCVEVRADDAEAVAAVLGLDDPASHARAVAER
GVLATLEAGCTAPVGAYSEFGTAEDAAILTLQAGAFALDGSTRVVREASVTIDLSDVGAD
PLHPRWRDAARELGRTVGQKLLDAGAAEVIAASVPE
>C9NLV3|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio coralliilyticus ATCC BAA-450|TrEMBL
MTQSTPIRIATRKSPLALWQAYYVRDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYANIDEL
PQGAVVGTCSLRRQCQIKEYRPDLVIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYSLLDGDDIWLRALVGEPDGSKIVRGEIKGSRADAEKLGVTLANQLLDDGA
RDILTRLYADHE
>B9P0P1|hydroxymethylbilane synthase|EC 2.5.1.61|Prochlorococcus marinus str. MIT 9202|TrEMBL
MTNFKLKIASRRSKLAMVQTLWVKDQLERNIPNLDVSIEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVGHADIAVHSLKDLPTNLPTGLKLGCITKREDPADALVVSKKNDCYKLE
TLPEGSIVGTSSLRRLAQLRNKYPHLVFKDIRGNVITRIEKLDAGEFDCIILAAAGLKRL
GFESRIHQIIPSEISLHAVGQGALGIECKSDDKKVLEIINVLEDKPTSQRCLAERAFLRE
LEGGCQVPIGVNSNIDNGQLYLTGMVASLDGKKLIKDQVIGNINNPELVGIELAKRLKFQ
GADKILSEIFEEFRENKN
>G7R603|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain 'clone D i2')|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>B3WQV3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli B171|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>D7AFL2|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacter sulfurreducens (strain DL-1 / KN400)|TrEMBL
MALNRLRIGTRASQLALWQANWVKSELEKRYPGMEVELVKIKTIGDKILDVPLAQVGGKG
LFVKEIEEAMLRGEIDIAVHSMKDVPTEFPEGLGLVCITEREDPRDAFISNGVTFANLPQ
GAKIGTSALRRQAQLLKVRPDLEMVIIRGNVETRIRKLTEDKLDAVILAAAGLKRLGFTD
VVTEYLPVDLSLPAIGQGALGLECRLDDQAVRETIDFFNHPDTAHAVRAERALLWRCEGG
CQVPIAAHGQVSGDSLTLTGFIASVDGTRSVKESISGPVTDCEKLGIALAEKLLADGGHE
ILAEVYQREVSREKEIPV
>G2BWK6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli STEC_H.1.8|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F3WXY5|hydroxymethylbilane synthase|EC 2.5.1.61|Sphingomonas sp. S17|TrEMBL
MVRFRLGTRGSPLALTQAHMVRAALADAQGWDEDAIEIVPIKTTGDRVQDRALAEIGGKA
LWTKELDRALLDGEIDASVHSMKDVETIRPDWLHIAAMLPRADVRDRLIGAETIAELRPG
AVVGTSSPRRRAQLLSHRPDLTITLLRGNVDTRLAKLASGEMDATLLAAAGLDRLGREVG
HAVPTDQMLPAPPKARWGSRRAPTMQRRPC
>C0ZUV5|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus erythropolis (strain PR4 / NBRC 100887)|TrEMBL
MSVTTPRSGSPLRIGTRGSLLATTQAGTVRDALIAAGHPAELVIIKTKGDQSTDPVQKIG
VGVFTAELREALLDNRVDVAVHSYKDLPTAQDPRFVIAAIPPREDPRDALVARDGLVLGE
LPAGSKVGTSAPRRVSQLKALGLGLDIVPLRGNLQRRLGKVESGELDAVILARAGLSRIG
LLDLITENIEPVQMLPAPAQGALAVECLSANVELAAILAEHDDAGTRAAVTAERALLAEL
EAGCTAPVGAIAEIVESLDDDGRIFDELSVRGCAAAIDGSDVIRTGAVGAPDKAEELGRA
VARELLELGARELMNVTTGEAADV
>D3SBN1|hydroxymethylbilane synthase|EC 2.5.1.61|Thioalkalivibrio sp. (strain K90mix)|TrEMBL
MKPLRIATRKSPLAMWQAEHVAARLRGLHPDLPVELVGMTTQGDRVLDSPLARIGGKGLF
VKELEVAMLEDRADIAVHSVKDVPMELPADLVLPVILDREDPLDAFVSNTYAHVDELPQG
ARVGSSSLRRQCQLRARRPDLKITDLRGNVNTRLGKLDAGEYDAILLAAAGLKRLGFDER
IRARLEPAVSLPAVGQGAIAIECRENDPEIAALIAPLNDRDTSDRVRAERAFNRRLEGGC
QVPLAGHATLDGDRLRLDGLVGAVDGSQLLRRQVEGPRGDAEALGVQLAEQLLELGAGEL
LAAAHAENAASTKGS
>E6TZR5|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4)|TrEMBL
MRKIIVGSRKSNLAMTQTKWVIEQLKSLGLNYEFEIKEIVTKGDKILDVTLSKVGGKGLF
VKEIEKAMYDGEIDIAVHSMKDLPAEIADGMAVGAIPKRVDPRDAFISNSGKGLMDLPAG
SIVGTSSLRRSAQVLAKRPDLEIQWIRGNIDTRLRKCREENFDAIILAAAGIERVGWTSD
IVTEFLEPEVCLPAVGQGALGIECRADDKEVLALLAKINDSDTEKTVTAERAFLHTVEGG
CQVPVAGYATLQDNGEIALTALVGSPDGQQIFRESIAGTDPVAIGKEVAQRMLKAGAKKV
LDEVKADLDQ
>F2L4T1|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoproteus uzoniensis (strain 768-20)|TrEMBL
MKLRVATRGSKLSLLQTELFIKSIKEVEPDLEFEIVVVKTTGDLVQDRPLYAIGVKGVFE
KEVNLAVLRGQADVAVHSLKDLPSEIHEDLVVAGYSKRDSPYDAIASTRGYDVWGLPRGA
RVGTSSVRRGAFLKSIRPDLHIEPLRGNVDTRIGKVLSGAVDAAVLAEAGVRRLYGENPP
VEIRRVKPDEIPPPPGQGIVAAVARKDDRGIIDLLRKASDPRAALEARAERAFLKEMGGG
CHVAVGGLATATPNGIEFLAGWASVDGSRKVLVKAFGESPEEVGVRAARMLKSALGPPHG
HRV
>E7WRC0|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 515920-1|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>Q26GX5|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacteria bacterium (strain BBFL7)|TrEMBL
MSLKIRIGTRDSQLAMWQATTVQSQLNALGFQTELAPVKSQGDLNLDEPLYEMGITGIFT
KTLDVALVKGDIDIAVHSLKDVPTQLPKGMVQAAVLERASQKDILVYKSSFNPDEAMTIA
TGSLRRKAQWLNMYAQHHVVDLRGNVNTRLSKLHSNKDWNAAIFAKAGLDRIGLLSQLRG
NYGFEYSDLDSFVPAPAQGAIMIAAMGHNTAVLEAVSQLNHAQTQRCVDIERRFLRELEG
GCTAPIGAIAQVHDNKIDFTGCLLSIDGTERIDVKDQINLTETDVDLGLAFAKAQSEKVF
AKGGKAMMETIKASLTS
>A3ZIU4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 84-25|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>A6GUG3|hydroxymethylbilane synthase|EC 2.5.1.61|Limnobacter sp. MED105|TrEMBL
MKIRIASRESRLAMWQAEHVRDLLLALPGVSGVEIVGMTTKGDQILDRSLAKIGGKGLFI
KELEYALLEGRADLAVHSGKDIPMDVDPEFQLLGFMTREDPHDAFVSNDYASLADLPAGA
VVGSSSLRRQAQVLARYPHLKVEPLRGNLDTRLGKLDSGQYQAIVLAAAGLKRLGLHSRI
RNVIESTDMLPAVGQGALGLEIRAGDSQLAELVKPLIDPVCTALVSAERSVSKALGGSCQ
VPIAGYATLNDAQTFTLRGLVASPDGKAVIEKSAQASLQDWETAANRVIEGLLQEGAQAL
IESAVQQFKG
>F9ZTW9|hydroxymethylbilane synthase|EC 2.5.1.61|Acidithiobacillus caldus (strain SM-1)|TrEMBL
MPTHHRQEMSRTSSVTPLRIGTRASPLALWQAEHVRAGLLRAHPEIPVEIVPMTTQGDRM
LAVPLHEIGGKGLFVKEIEAALLEGTVDLAVHSMKDVPAQQPEGLEIAAILAREDVRDAW
VSNTFARPEDLPQGGRVGSSSLRRRAQLLHRLPQTVVLDLRGNVATRLRKLDAGDYDGIV
LAAAGLKRLGLLERIRHYLEPELSLPAVGQGAIGVEIRSDDARTRTLLKPLNDPTTSRCV
GAERHMNRLLGGDCRLPVAALAEADGTGLRLRGLVASPDGRELLRAEAVGSLAHSVGEQV
AQALLAQGAQHIIDEVKRA
>A0M6C2|hydroxymethylbilane synthase|EC 2.5.1.61|Gramella forsetii (strain KT0803)|TrEMBL
MSKVIRIGTRDSELALWQAKTVQKALESTGHQTELVPVKSTGDLNLDQPLYEMGITGIFT
KTLDVAMINGDVDIAVHSMKDVPTALPKGIVEAAIMKRANSKDLLIHKGVEFLENEEGTI
ATGSLRRKAQWLHKYPNHKVVDLRGNVNTRMQKLNDNNWNGAIFAAAGLERIEIKPENFI
DLNWMIPAPAQGAMLIVAMEEDEYCRRALSVLNHKESELCVHVEREFLKTLEGGCTAPIG
ALAKILNNHVHFHGALFSLDGKKKMEVERSLPVAEIEDMGKECAQEILKNGGKELMANIK
SVLNN
>G0LFE7|hydroxymethylbilane synthase|EC 2.5.1.61|Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23)|TrEMBL
MTTRSRTRGTLTLATRGSDLALKQATSVQEALTDERYEVDLIEVETRGDQIQDELIHQLG
KTGAFVRALDKKVLDPTAEADAAVHSMKDMPTDSPDDLVVAGIPQRAPPGDLLITTDGQR
LSDLPSGATIGTSSLRRQAQLLDQRTDITVEPLRGNIDTRIEKLLAPSLQTEHEQRIEAE
QGEITNTENAGSDDEDIDRDETDKELPEFEQSIEEWFNELSEIERRALERSVETEYDAIV
LAEAGLQRSGLIHHIEYVQLDTTTFVPAPGQGAIAITTQGEANATAQIREAIDHPRTRVE
TTVERTVLAELGGGCIAPIGVHATLQGEYVHVAAQVFASDGTETVDGSRNLPVDAHADAA
AQFANKLADRGADELIAAARVAADESSNTESTGE
>G8VK52|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes TypeIA2 P.acn31|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>G8VK52|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes TypeIA2 P.acn31|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>E1SWW1|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoanaerobacter sp. (strain X513)|TrEMBL
MKKVIKVGTRSSELALKQTAMVINEIKKFRQDFEFEIVKITTQGDALIDKPVSEIGGKGV
FVKEIESALLKGEIDMAVHSMKDMPYEIPKGLKLMAVLKREDPKDVFVSGDGTQFMDLKE
GAKIGTSSLRRQVQLKALKPDIQIVPIRGNVRTRLKKMEELNLDGIVLSAAGLHRLGLEN
IITEYFPPDVVVPAPCQGILAVEIAESFDNIFQEFYPYIVDRKTFFEASVERELLKAFGV
NCRQPFGAYAQYRKEEDEEKINIKVAYQKENKLLKSEVTGLIEETDKMIEKLIEEFGGI
>Q1ZJ61|hydroxymethylbilane synthase|EC 2.5.1.61|Psychromonas sp. CNPT3|TrEMBL
MSNKIIRIATRHSPLAMWQANFVKSELLKWHPELQVELLAMKTKGDKILDTPLAKVGGKG
LFVKELEVAILEGRADIAVHSMKDVPVDFPEGLGLAVICEREDPRDAFVSNHFANIAALP
QGSVVGTSSLRRQCQLRAQRPDIKVKDLRGNVNTRLAKLDAGEYDAIILASAGLIRLDMH
DRIASYMSVEESLPAVGQGAVGIECRLDDMQTLALLKPLEHRITRLRVTAERAMNLALQG
GCQVPIGSYCILKEDTLWLRGLVGSVDGTHIIRKEIRGKVADAEQMGLNLAQQLLESGAD
KILADVYRDNA
>G7SYF7|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella pullorum (strain RKS5078 / SGSC2294)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
PRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H4W3R3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC6D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F7TEP6|hydroxymethylbilane synthase|EC 2.5.1.61|Pasteurella multocida subsp. gallicida str. Anand1_poultry|TrEMBL
MVVMMTRKSLIIATRQSPLALWQANYVKACLEKIHAGLVVELVPMVTKGDVILDTPLAKI
GGKGLFVKELEQALLKGEADIAVHSMKDVPMQFPAGLMLSTICEREDPRDAFVSNSYRTL
MELPAGAVVGTSSLRRQCQLKQLRPDLHIHSLRGNVGTRLAKLDNGDYDAIILAAAGLIR
LGQQQRITSLIDVTQCLPAAGQGAVGIECRQEAEIELLLAPLADPETTACVLAERAMNRH
LQGGCQVPIAGYAIIEEGQLFLRALVGEIDGSRILRAEGRSAVADAEILGIQVAEKLLQQ
GADKILQTLYSN
>D9SK98|hydroxymethylbilane synthase|EC 2.5.1.61|Gallionella capsiferriformans (strain ES-2)|TrEMBL
MSPASSTLPTPPARLVIASRESALAMWQAEHIRDRLRALYPQTDVSILGMTTQGDQILDV
SLSKIGGKGLFVKELETALEDGRADFAVHSLKDVPMVLPEGFVLAAIGEREDPHDAFVSN
NYENLAALPAGSVVGTSSLRRESQLRARFPHLVIEPLRGNVQTRLRKLDEGLYAAIILAA
AGLKRLGLATRIRAVISSEDSLPAVGQGALGIECRADRLDVIAALQPLHHPDTAACVFAE
RAMSRALNGSCQVPLGGFAEVQNGQLRMRGFVASPDGQRVIRAEAMGEIAAPEALGGQIA
KSLLAQGAGEILAALNG
>C5C5B3|hydroxymethylbilane synthase|EC 2.5.1.61|Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)|TrEMBL
MTTSTSPEESATLVRVTSTRTLRVGTRASALATTQSEWAGEAIAARVAAATGSDVEVELV
RVTTTGDVLTGSLASMGGTGVFVTALREALLDGRCDVAVHSLKDLPTAAAPGLVLGAVPQ
REDPRDVLCARAGAGLADLPAGGRVGTGSPRRAAQLRRARPDLEIVDIRGNVDTRLSRIS
PGKGDLDAVVLARAGLARLGRLDAVTEALDAGVMVPAPGQGALAVEAVDAAPDWLLAGLR
AFDDAPTRLAVTAERAMLARLEVGCSAPVGALATLAGSQLLLRTSVGEDAEDLGGSFRVG
LPDDDDARLDAAAGLGRAAAEAALARIEAGGPPS
>F1Y371|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. 1125|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>I4XLK2|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus atrophaeus C89|TrEMBL
MRTIKVGSRRSKLAMTQTKWVIKKLEEIDPSYTFEIKEIVTKGDRILDVTLSKVGGKGLF
VKEIEQALLNEDIDMAVHSMKDMPASLPEGLTIGCIPKREDPRDALISKRHQKLSDIKEG
GVIGTSSLRRSAQLLVERPDLTIKWIRGNIDTRLHKLETEDYDAIILAAAGLSRMGWKDD
VVTEFLEPERCLPAVGQGALAIECRESDEELLRLFSQFTDEYTKRTVLAERAFLNAMEGG
CQVPIAGYATINDQDEVQLTGLVASPDGKTIFKEKVAGNDPEEIGKRCAALMSDKGAKAL
IDRVKQELDHDAE
>F2J251|hydroxymethylbilane synthase|EC 2.5.1.61|Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1)|TrEMBL
MRIGTRGSALALAQAHETRARLMAAHGLAEDAFEIVVIKTSGDRILDRPLSEVGGKGLFT
KEIEEALLDDRIDLAVHSSKDMPTLLPDGLALTAFLPREDVRDAFVSPKAKMLMDLPQGA
VVGSSSLRRQAMIKRLRPDIEVVMYRGNVQTRLQKLEDGAVDATLLAYAGLRRLGLADVV
TSLLDTDAFLPAVGQGAICIESRVEDAATLGLLAAIHDRETEIRLTAERAFLAELDGSCR
TPIGGLARIDGDRLSLAGIILRPDGSEAHEIAREGAVADAEAIGREAGRTLKAAGGPGFF
AA
>I6FYA3|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri 1235-66|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMANHPGLIVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLEKRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNKYNTLDELP
AGSIVGTSSLRRQCQLAKQRPDLIIRSLRGNVGTRLSKLDNGDYDAIILAVAGLKRLGLE
SRIRAALAPEVSLPAVGQGAVGIECRLDDQRTQALLAPLNHEETALRVKAERAMNTRLEG
GCQVPIGSYAELINGEIWLRALVGAPDGSQMVCGERRGAAQDAEQMGISLAEELLENGAR
AILAEVYNGDAPA
>A1AHX1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O1:K1 / APEC|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F0C8R8|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthomonas gardneri ATCC 19865|TrEMBL
MTTLRIATRKSPLALWQSEHVATALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLF
LKELELAMLRGEADCAVHSLKDVPMELDAPFVLPAIMERGDAADALVSNLYATVQALPLG
ARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGFDAR
ITARLDVPEWLPAPAQGAVAVECRGDDAHIHGLLAVLDAGRTRACVEAERAMNRALHGSC
HVPVAAFARWEGDGLFLQGMVGSASDGRLIHAEAHGSAEDTESLGRLVAQGLFDKGAAQL
LAEL
>G2ZU46|hydroxymethylbilane synthase|EC 2.5.1.61|blood disease bacterium R229|TrEMBL
MSSNARPTSVESPLAAQAPTQLVIASRESRLAMWQAEYVRAALQKYYPACDVSILGMTTR
GDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMELPAGFALPIILEREDP
RDAFVSNHYADLAALPAGAVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLSKLDRGDY
AAIILAAAGLKRLGLSERIRAVIAPEASLPAAGQGALGIEIRADRPDVQAWLAPLHHAPT
ALAVTAERAVSRRLGGSCQVPLAAFAQWTDDGALRLRAFVASQDGRRKLAAEGETTPATL
AEAEALGARVAQQMLDGGAHDILAALGADAPPAT
>G2JXV7|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes serotype 1/2a (strain 10403S)|TrEMBL
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEAIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNQVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPEVCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEFVQFKGLVGNADGSIILESEQVGANPSEIGNKVAEDLLSEGAD
TIIKELRNV
>G6XGH6|hydroxymethylbilane synthase|EC 2.5.1.61|Gluconobacter morbifer G707|TrEMBL
MRFMNAPVLASDALQKVAAEAVRRSHAVETPSRRTLPLRVGTRASPLALVQTRNFLTRLT
RFCPILRDMGAFQEHQISTEGDRNLVQRLAEIGGKGLFAKEIHEALLAGRIDFAVHSLKD
LETNLPPGLVLACTLKREDARDTILLRDRTVEVDPARPYDCLPEGALIGCASVRRQAQML
HVRPDLKFCLLRGNVQTRLDKLRAGACDATLLALAGLRRLGMEDRVDVVLEPDQMLPASG
QGIVGVTVRESDAELRELLSAIEDPEARAVSTAERALLAELDGSCRTPIGGYARIEKGIL
KLTGMVASEDGTFLLKREIEGPPLEAARMGTELADELRRETPPHIFAEITRA
>I5DBR8|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli FDA505|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I4CY19|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas stutzeri CCUG 29243|TrEMBL
MSREIRIATRKSALALWQAEYVKARLEASHPGLKVSLVPMVSRGDKLLDAPLAKIGGKGL
FVKELETALMENEADIAVHSMKDVPMEFPEGLGLYCICEREDPRDAFVSNHFDDLDALPP
GSVVGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFGE
RIRSSISVDESLPAGGQGAVGIECRTTDSELHALLECLNHAPTATRVVAERALNKRLNGG
CQVPIACYAVLEGEQLWLRGLVGQPDGTVLLRAEGRAPAADAEALGVQVAEALLDQGAEQ
ILQAVYGEAGHA
>D6Z824|hydroxymethylbilane synthase|EC 2.5.1.61|Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578)|TrEMBL
MIRVGTRGSLLATTQAATVRDAIRSLGESAELVIVATVGDKSSGPITEIGVGVFTSALRD
ALIAGEIDIAVHSLKDLPTAQDPRFSLVAVPERADPSDVLVSRSGLPLAELPPGSTVGTG
APRRAAQLRLARADLEIQPIRGNLDTRMRKVATAECDAIVVARAGLLRLGREQEATEVLH
PAVMLPAPGQGALAVECRSDAPASLTETLAKLDHEHSRAASAAERAVLAELSAGCSGPVG
ALARMTGQTLRVEASVIAIDGSRSVRAHAETSVLGTELLSQEQHAVALGRRVAESLRSMG
AMELIGDV
>H2JNS0|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces hygroscopicus subsp. jinggangensis (strain 5008)|TrEMBL
MTEKALRLGTRRSKLAMAQSGQVAQAVRQVTGRPVELVEITTYGDVSREALAQIGGTGVF
VTALRDALLRGEVDFAVHSLKDLPTTQPEELVLAAVPVREDPRDVIVARDALKFTDLPRG
ARIGTGSPRRMAQLNAYARTHGLDIETVPIRGNVDTRIGYVHAGELDAVVLAAAGLNRIG
RIDEVTDFLSVDTVLPAPGQGALAIECRAGNTAQDAALVAALGELDDPFTRAAVTAERSL
LAALEAGCSAPVGALADLLADGQTVKEMRLRGVVGTTDGTRTVQLSTTGPVPQTHDRATA
LGRELATEMLAQGAAGLMGERAH
>A1UAP8|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium sp. (strain KMS)|TrEMBL
MSNADTPIRIGTRASLLATTQAGTIRDALIARGHAAELVLISTEGDRNQGPIADIGVGVF
TAALREAIHDGRVDAAVHSYKDLPTAADERFTIPAIPRREDPRDALVARDGLVLGELPAG
STVGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVGNGELDGIVVARAGLARIGRLGD
VTETLEPVQMLPAPAQGALAVECRAGDTGLIALLAELDDADTRAAVTAERVLLAELEAGC
SAPVGAIAEVVESIDEDGRVFEEVSLRGCVAALDGSDVIRASGIGTPGRAADLGVSVAAE
LFELGARELIADHH
>I4WND3|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodanobacter sp. 116-2|TrEMBL
MNPATLRIATRKSALALWQAEHVATLLRTTHPGLTVELVPMSTRGDEILDQPLATIGGKG
LFLKELEVAMLEGRADLAVHSLKDVPAQLEPGFALPAILPRADAADAFVSNHYDDLAALP
HGARVGTSSLRRQAQLRALRPDLVLLDLRGNVGTRLGKLDAGAYDAIVLACAGLERLDLA
ARIRSRLAAPDWLPAPGQAAIAIEAREGQPGVLALLAALDDADTRLTVSAERAMNQALGG
SCTVPVGAWCMLGEHGLHLRGLVGDAAGGRLLRAEASGPSNQAIALGRQVAAELLAQGAA
EFLGL
>Q143B5|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia xenovorans (strain LB400)|TrEMBL
MTTRGDQILDRTLSKVGGKGLFVKELEAALADGRADLAVHSLKDVPMALPEGFALSTIME
REDPRDALVSNTYDSLAALPEGAVVGTSSLRREAMLRMRYPHLEVRPLRGNLDTRLAKLD
RGDYAAIILAAAGLKRLGLGERIRALLDPEDSLPAAGQGALGIEIRADRAELAAWLAPLH
HEHTAAAVEAERMVSRALGGSCEVPLAAYATWHDGALHLRGIVATPDGQRVLSAQASAPA
TSVEQAIALGQEVAGALEQQGAMEIVRALGAANGAAAADSAVTGE
>A2RAF5|hydroxymethylbilane synthase|EC 2.5.1.61|Aspergillus niger (strain CBS 513.88 / FGSC A1513)|TrEMBL
MSSAPPHATNPSSRKTFTIGTRKSKLALLQTDLVQAALKQTWPDYEFKIHSRETAGDQNT
TIALRDFTTKNLWTQELEDLLIAGQVDFIVHSLKDVPTLLPSSCTLGPMMKREDTRDVLV
MKKGLSYTSLAELPEGSVVGTSSIRRTAQLARRYPHLKVMDVRGNIGTRLSKLDAEDGPF
TCLILAAAGLLRLDLGDRITSYLDSKNGGMLYAVGQGALGIEIRKDDQQVLDMLQNIGHK
ETTFACLAERSLLRTLEGGCSAPLGVESEWVNGALTMRSIVVSVDGKESAEVEVDGAVDS
PQAAEEFGVTVAKALVEKGAGKILDEIQRNKQTA
>E0MQD3|hydroxymethylbilane synthase|EC 2.5.1.61|Ahrensia sp. R2A130|TrEMBL
MTQFLIATRKSKMALAQANHVADLLREAVPGLDVDLAENNPRGDRDQISKLDRHGGKGGA
FVAEIRADIVAGRSQVAMHSLKDMPGNEETPGLVIGAYLTRDDPTDSLVLRDGITMDQMR
ETQGDGLKLGTNSVRRAAFLRNLFPNAEIIHFRGAADSRIEKLDKGLMQQLVDGGEVGPA
DGILLATSGMARVGVSDRISHTFTTSEMLPAVGQGIVAVECGSSDWQTREWLARIDDANA
RACAEAEREVLWVLDGHCNSPIAAHSVIEGDTMTMESAVMEIDGDKIIRHTASGPAEYPR
ELGRTVGLALVAKGAQAIIEATRV
>B2N5F1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 53638|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>H8CFS0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1893|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>E0QN92|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus mulieris ATCC 35239|TrEMBL
MHMIGSAQRPLVIGTRGSKLALTQTQMVAADLEQRGLAVRIETFVTEGDTNRASLSSLGG
VGVFAAALRVALLEGRCDLVVHSLKDLPTVEVPGLVVAAIPARVDPADVLVARDGLRLAD
LPAAARVGTGSPRRARQLAAARPDLSLVDIRGNVPTRIGRVRGLGTRAEQIGLDQDRAKE
DLDAVVLARAGLRRLGVEDVATDDLSETILPAGGQGALALETVADGLAAEEGRILAQTLR
IVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGQLTWENNATELLAGVLELRARVVGDNG
ESVEVSGETTVLLGTDADQRDFALAAAEQLGVDLATELLANGAGEMANLQATKESGTTQS
>E0QN92|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus mulieris ATCC 35239|TrEMBL
MHMIGSAQRPLVIGTRGSKLALTQTQMVAADLEQRGLAVRIETFVTEGDTNRASLSSLGG
VGVFAAALRVALLEGRCDLVVHSLKDLPTVEVPGLVVAAIPARVDPADVLVARDGLRLAD
LPAAARVGTGSPRRARQLAAARPDLSLVDIRGNVPTRIGRVRGLGTRAEQIGLDQDRAKE
DLDAVVLARAGLRRLGVEDVATDDLSETILPAGGQGALALETVADGLAAEEGRILAQTLR
IVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGQLTWENNATELLAGVLELRARVVGDNG
ESVEVSGETTVLLGTDADQRDFALAAAEQLGVDLATELLANGAGEMANLQATKESGTTQS
>D0H1B6|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae RC27|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>F3W4M9|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella boydii 3594-74|TrEMBL
MMASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVP
VEFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIR
SLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECR
LDDARTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAP
DGSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>F9JSM2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21195|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>G0A0G0|hydroxymethylbilane synthase|EC 2.5.1.61|Methylomonas methanica (strain MC09)|TrEMBL
MADKTIRIATRQSPLALWQAEHVAARLAQAFPGLKTELVKMVTRGDKILDAPLAKVGGKG
LFVKELEQGLLEGTADIAVHSMKDVPVEFPDGLHLAVIMNREDPTDAFVSNRYGSLADLP
ANARIGTSSLRRQCQIKEKFPHAEILSLRGNVNTRLAKLDAGEYDAIILASAGLKRLGMG
ERITAQLSPEESLPAMGQGAIGIECRIDDADIHDYLKVLHDEATSIRVGAERAMNARLNG
GCQVPIAGFAEIRADRLFMRGLVGHPDGSVLYRAEAERPLAEAEQLGIAIADALLAQGAD
KILRELYQ
>G6Y6V1|hydroxymethylbilane synthase|EC 2.5.1.61|Mesorhizobium amorphae CCNWGS0123|TrEMBL
MQTTLKIGTRGSPLALAQAHETRARLMAAHGLQEAAFEVVVISTSGDRIQDRPLSEAGGK
GLFTKEIEEALLARRIDIAVHSSKDMPTLLPEGLELSAFLPREDARDAFVGKAAKRIADL
PQGAKVGSSSLRRQALIRRMRPDLDVVMFRGNVQTRLRKLDEGVADGTILAYAGLKRLGL
EHVVTDLMPLDIFRPAPGQGAICIESRIGDRDVEKMLMAIHDVPTGQALACERAFLAALD
GSCRTPIAGHATISGETLSFAGLIISPDGTTSHEVELDGPAKDAARIGADAARTVRTKAG
ETFFDGWA
>H8MXH1|hydroxymethylbilane synthase|EC 2.5.1.61|Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2)|TrEMBL
MKTVRIATRESPLALWQANHVASLLKERNPGLEVTLVKMSTEGDRFLSAPLSAVGGKGLF
VKEIEQALLDGRADVAVHSLKDMTSVFPEGLILAALPAREDPRDAFCSPDGHTLAMLPAG
AKVGTSSLRRSCILRARRPDLEIVSLRGNVQTRLQKTRDLQLAGAMLAAAGLKRLGLDHH
ITQVVPVAESLPAVGQGVLGIQCREADADVRALLQPLEDALTRNAVRAERAFLAKLEGGC
TVPLAGHATVEDGQVYLRGLVGRPDGSLVVRGEVKGPVPEAERLGEALAEELLSRGAGDI
LRDFGRREGAPRA
>D1A492|hydroxymethylbilane synthase|EC 2.5.1.61|Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)|TrEMBL
MTALRLGTRKSLMATTQSRRVGDELTRLTGHAVELVGVTTEGDISRAHLAQMGGTGVFVS
ALRDKLISGEVDFAVHSLKDLPTAPAEGITLAAVYRRDDPRDALCGPLKLADLPRGARVG
TGSPRRVAQLRALRGDLEIVPIRGNADTRLRKVADGELDAVVLAYAGLGRIGRRDAVVEV
FDPADMLPAPGQGALALECRSDRLDLIELLATVDHAPTRAAVTAERTVLAVLEAGCSAPV
GAYATVEDSAEEEQPSLHLSACVAGIDGARQVRLSGSGHPERAEEIGRELAAQLLAQGAD
QLMGERHIEPR
>C5QXR7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis W23144|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSIIPDGLTLGCIPDREIPFDAYIAKNHIPLEELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDVLLPAIGQGALGIECRSDDKELLDLLAKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIVQDNQIEFTGLIMSPDGKERYEHTTLGSDPVQLGIEVSQVLKKQGAYDI
IKKLNEAE
>C9XAE5|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella typhimurium (strain D23580)|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHS
LDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELL
ENGARAILTEVYNGETPA
>H1RTT5|hydroxymethylbilane synthase|EC 2.5.1.61|Comamonas testosteroni ATCC 11996|TrEMBL
MKFSASSPTVIVIATRESQLAMWQAEHVQAILRGRGHSVDLLGMTTKGDLILDRALSKVG
GKGLFVKELEVALEEGRADLAVHSLKDVPMELPEGFVLACVMTREDPRDAFVSNRYASLD
ELPQGAVVGTSSLRRQALLQALRPDLKIEALRGNVNTRLRKLDEGQYDAIVLAAAGLMRL
EMSERIRARFDPAQMLPAAGQGALGIEVRADRQDIIDALAPLAHMPTWLTVTAERAVSRC
MGGSCSMPLAAYGRFEGDTLHMDAAWGDMEGSKGLVRVQASAQVTDFASANALGEQLAAQ
LQAAGAVPAAPKQD
>D6DJE4|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium saccharolyticum|TrEMBL
MNKKVRVGSRDSLLAVRQAELVMEAVRKASPETELTLVTMKTTGDRILNQSLDKIGGKGL
FVKELDLALMEGRSDLSVHSLKDMPMEIPEELPILAYSPREDNRDVLVLREGLSELPAHP
VIGTGSARRKIQAARIYPDAEFKGIRGNIHTRLRKLDSGEYDALILAAAGMIRMGLQDRI
SRYFSVEEIIPPAGQGIMAVQGRKDDSYPFLIKINSPKSQAMAEAERSFVKTLDGGCSSP
IAACALIEGDRLKLRGLYFEEKSGRWVVGSLEGSVQGPAELGRSLALRLKSEIEQEKV
>C6UIP9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain B / REL606)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDNLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H4A5K5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIGC93|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>I2W1V8|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 5.0959|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>E6SAF4|hydroxymethylbilane synthase|EC 2.5.1.61|Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP)|TrEMBL
MTALRLGTRRSALATTQSGWVADQLRAAGHDVELVEITTEGDVSGGLLTAIGGTGVFAAA
IRKALTDGRVDVAVHSLKDLPTAPEPGLVVAAVPAREDSRDVLVARDGLTLGELPIGSVV
GTGSPRRTAQLAALGLGLEIRPIRGNVDTRLRLVSSGEVDAVILARAGLARLGRLDVVTE
VLDPIQVLPAPGQGALAVECRADRPDVLEAVSVLEDADTRASITAERALLAALEAGCTAP
VGALAEVVDGEEGLELSLRAFAGTEDGRIDLRRSLTGRYDDPESLGRRLAQILLEDGAAD
LDRPSTIASRPPEPVS
>H7X307|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 129-258|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>B1QK23|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium botulinum Bf|TrEMBL
MNFIIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVK
DIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLREGAK
IGTSSRRRAAQLKLLRSDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLIT
DYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
>I2X3U1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 2.3916|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>D0CQY2|hydroxymethylbilane synthase|EC 2.5.1.61|Silicibacter lacuscaerulensis ITI-1157|TrEMBL
MTLTLPTPASPLKIGTRGSPLALAQAHETRQRLCDAFDLPEQAFEIVVIKTTGDNRAMID
ADRPLKEIGNKGLFTKEIEEAMLGGYIDIAVHSTKDMPVEQPQGLVLDTFLPREDVRDAF
ISPRLNSIHDLPEGAVVGTSSLRRRAQLLYRRPDLNVVEFRGNVQTRLKKLADGVAECTF
LAMAGLRRLNMQDVPATAISPDDMLPAIAQGTIGIERRADDHRAAEMLEAIHHPETAQRL
AAERALLAALDGSCETPIAGLAEITDGQLRLRGEVLRPDGSESVVSEQMGATEDATEMGR
AMASDLLRQAGPGFFEWRNL
>I6AM90|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia thailandensis MSMB43|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAXXXXLDVRPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLAARVRALL
DVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHATALAVEAERAVSRALGGSCEVPLA
AHAVWRGDELHLTGSVSTTDGARVLAAHAQSRAATAADALALGRAVSDELERQGARAIVD
ALVAASAQAQQGGA
>Q29EW7|hydroxymethylbilane synthase|EC 2.5.1.61|Drosophila pseudoobscura pseudoobscura|TrEMBL
MSAQEKVIRVGSRKSELALIQTKHVIGRLQKLYPKQRFEIHTMSTFGDRVLNVSLPKIGE
KSLFTRDLEDALRNGGVDFVVHSLKDLPTALPTGMAIGAVLEREDARDALVLRENFQGHT
IASLPQGSVIGTSSLRRTAQIRRLYPHLIVCDIRGNLNTRLAKLDAADSRFAGIILAQAG
LVRMGWMSRISQVLEPTDLLYAVGQGALAVECRANDVQVLAMLQKLMCLNTTCRILAERS
FLKTLGGGCSAPVAVWSNLQGEPLNANSQDVGLSLTGAVWSLDGAIEIRNHLSCALSEKP
TGKRGAQQQLQEQQENSSSCDSPPACKRPRNGNCSSGSGSGSSDSNSNSSSPPRPQGSPP
VICEDVAACEALAGYSVEQLTDLASQCPVLSNNNTLGASGDAGGGDADTTNANRCPMQRD
VISHSGGDAAGDSDTASNVNPTPHCPLQMPVGVDFMGECPYVNNETKISYAKAGKCPVTH
AAAGAVPAQPILPTPPSSRASIGSSIGDEVDNVATVSSKCPFAAMHQGSGLEAPPKESGA
PAKCPFLQKTVQMFDYADEEQPKPQTVLIEDVDNLFCGLYQHPCYSRQVYERANLLGKNL
AEELIKKGALDVMKIAQAEIHGKVGTTTTS
>H4CDQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIG1770|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>E3JFI7|hydroxymethylbilane synthase|EC 2.5.1.61|Buchnera aphidicola subsp. Acyrthosiphon pisum (strain TLW03)|TrEMBL
MYNKTLRIATRKSPLALKQTKYVQKKILSLYPDLNIKLVPIVTHGDNILNKSLSKIGGKG
LFIKELELALLENKADIAIHSMKDLPVKITKELCLVSICKRGNALDSLVSNNYQSINQLP
KGAIVGTSSLRRQCQLITYRPDLIISPLRGNIETRIAKLDQGKYDAIILATEGLNRLRLK
NRITQIIPAELSLPSCGQGAIGIQSRLHDKKVLFFLSRLNHINTFIEINAERAFCRKLES
GCQIPIGSYAILKKNKIWLRGLVGSPNGKIILKGERIGCYNTGEKMGYSLADELLKNGAK
NILNNLHIKQSYCI
>I0M3H9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Heidelberg str. 41579|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>Q0FDA0|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacterales bacterium HTCC2255|TrEMBL
MRFTPNSPLVIGTRGSPLALAQAHETMGRLIRSTGLDESCFKITVIKTSGDKIQDRPLSE
VGGKGLFTKEIEDAMLDYGIDIAVHSMKDMPVICPEGLKLSCYLPREDVRDSFISTKYKN
INELPKGATVGTSSLRRRAQLLNKRPDLKIVEFRGNVQTRLRKLNEGVAEATFLACAGLN
RLGRNEISNPIEPDDMLPAIAQGCIGIEQREGDTEIAEILTKINDKSASLRLAAERTLLA
ELDGSCQTPIAGLAELDGQKMRLRGEVIRPDGSEVLKDEIICHVNEGVEMASGMAKRLRD
QMGEDFF
>E0R2X8|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli NC101|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E6NK52|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain F30)|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLERKFIKGLNGGCQ
IPIGVHASLTGDRVKIRAVLGLPNGKEVITKEKQGDKTRAFDLIQELLEAFLQSGAKEIL
EKAQLF
>F7SAV9|hydroxymethylbilane synthase|EC 2.5.1.61|Acidiphilium sp. PM|TrEMBL
MFLAALREICPALGFAPDAFAPEIISTTGDRVTDRPLAEIGGKGLFAKEIHEALLDGRID
FAVHSLKDLETALPDGIILACTMKREDARDALILADGLGPVNDGDIWSSLPKGARVGTSS
VRRQAQLLHARPDLQIGLLRGNVRTRLDAARIGTFDATLLALAGLRRLGFEEEVAAAIDP
EAMVPAACQGIVGITVRAADSRLAELLAAIENHEAKAVSKAERALLAALDGSCRTPIGGH
ARLLPDGNLHLTGLTARPDGSFLLKRSEVANAADAARLGAELGASLRRDSPADIFLD
>I4E7L3|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis alpha522|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESESLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>Q0BPD0|hydroxymethylbilane synthase|EC 2.5.1.61|Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)|TrEMBL
MQPAHPPSGHPSGPTTPSSTPPSSHVGMHGLPLRVGTRASPLALVQTRAFLARLRSFCPI
LRDMEVFEEHQINTTGDRVQDRRLAEIGGKGLFAKEIHEALADRRIDFAVHSLKDLETQL
PPGIVLACTLKREDARDAIILPPGFTPPPPGDPFSVLQQGALVGTSSVRRQAQLAHARPD
LRFATIRGNVQTRLAKLARGECDASLLALAGLRRLDMEQAASVVLDTEIMVPAACQGIVG
VTVREDDYALRDLLAGIEDREAKAVSTAERALLNLLDGSCRTPIGGHARILSGGVLHLTG
LVAAEDGSFLLRRTLQGAVSEAEALGAELGRSLRADSPPDIFLD
>F1YIQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Gordonia neofelifaecis NRRL B-59395|TrEMBL
MHDTAGGTIRIGTRGSLLATTQAQDIADRLTAAGHPAELVIISTAGDTSSAPVAQIGVGV
FTTAIRLALRSGECDVAIHSYKDLPTAPEDDLAMAAVPTRVDPRDALVSRDGMVLGELPS
GSVVGTSSPRRAAQLRALGLGLEIRPLRGNLDSRLGKVASGELDAIVVARAGLVRIGRAD
VVTEALDPLVMLSAPAQGALAVECRSDDAELVRILAELDDPSTRAAVDAERAVLATLEAG
CTAPVGALAEVVDSIDEDGRIFAELSLRAAVAAEDGSEVIRASVVGPVDRAAQLGKDLAA
ELLELGAAALVPTGE
>F1YIQ8|hydroxymethylbilane synthase|EC 2.5.1.61|Gordonia neofelifaecis NRRL B-59395|TrEMBL
MHDTAGGTIRIGTRGSLLATTQAQDIADRLTAAGHPAELVIISTAGDTSSAPVAQIGVGV
FTTAIRLALRSGECDVAIHSYKDLPTAPEDDLAMAAVPTRVDPRDALVSRDGMVLGELPS
GSVVGTSSPRRAAQLRALGLGLEIRPLRGNLDSRLGKVASGELDAIVVARAGLVRIGRAD
VVTEALDPLVMLSAPAQGALAVECRSDDAELVRILAELDDPSTRAAVDAERAVLATLEAG
CTAPVGALAEVVDSIDEDGRIFAELSLRAAVAAEDGSEVIRASVVGPVDRAAQLGKDLAA
ELLELGAAALVPTGE
>F3UQI1|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus sanguinis SK355|TrEMBL
MKVIKVGTRKSKLAMTQTQQLVDQLKALHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVF
VKEIERALLAGEIDMAVHSLKDMPAKLAEGCALGAISQREDVRDCLIFRQSGQTLADLPE
GALIGTSSIRRQVQLQAQRPDLAFKPLRGNIDTRIKKLEEGEYDAIVLAMAGLKRLGWLD
QSRLHIQPLETSLCLPAISQGALAVECREEDEELRSLLAAVQDEKTAAEVAVERAVLAQM
NADCTFPIAAFAQKNGQNYQLEAMLAKEDGQCIFVSLQGQDGQELAEQAVRQLADKGAVG
MPWLKK
>I0EVH6|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori HUP-B14|TrEMBL
MEKLVIGSRGSELALWQANHIKERLKKECFIESEIQIVKTRGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVKEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKQGDKTKAFDLVQELLEAFLQSGAKEIL
EKAQLF
>E3F457|hydroxymethylbilane synthase|EC 2.5.1.61|Ketogulonicigenium vulgare (strain Y25)|TrEMBL
MLNALPTPAQPLRIGTRGSPLALAQAYETRDRLAQAFALPHEAFQIEVIKVTGDMVQDKA
LREIGGKGLFTREIEDALLDGSIDIAVHSMKDMPVEQPAGLLLDCYLPREDVRDAFVSLH
GWTLADVPAGKVIGTSSLRRRAQILARRPDLTVVEFRGNVQTRLKKLDEGVADATFLAMA
GLNRLQRGDVPLKALEVEQMLPAVAQGAIGIERRADDRIIEGMLAVIHDGPTGVRLAAER
AFLAGLDGSCHTPIAGLAEIIGDQIRLRGEVLRPDGSEAICDDMRGAAVDAAQIGAEMAR
KLRGLAGEGFFTLG
>H8HJK0|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis RGTB327|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>H8HJK0|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium tuberculosis RGTB327|TrEMBL
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRH
>C2HT59|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae bv. albensis VL426|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGNTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>B6BBE9|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacterales bacterium Y4I|TrEMBL
MASSMTLTLPTPASPLKIGTRGSPLALAQAYETRSRLAAAFDLPQEAFEIVVIRTTGDNQ
ALIAADKPLKELGGKGLFTKEIEEDLLSGAIDIAVHSMKDMPVAQPEGLALDTYLPREDV
RDAFISPALKSLHDLAEGAVVGTSSLRRRAQLLNRRPDLKVVEFRGNVQTRLRKLSEGVA
DCTFLAMAGLNRLAMADVPANPIETSDMLPAVAQGAIGIERRADDGRAAEMLAAIHDGET
GLRLAAERAFLAALDGSCETPIAGLAELHGSTLRLRGEVLRPDGSESISDDQTCPVEDGA
ELGREMAAKLLEKAGKGFFDWKS
>A8A6Q9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O9:H4 (strain HS)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F4XML4|hydroxymethylbilane synthase|EC 2.5.1.61|Moorea producta 3L|TrEMBL
MTSTVTSPARTIRIGSRKSQLALIQTYWVQEQLKKHFPDREFEVQTMSTHGDKILDVALS
KIGDKGLFTKELELGMLRDEIDFAVHSLKDLPTRLPEGLVLGCVTERENPADALVMHQKH
LDKQIETLPEGSIIGTSSLRRLAQLRYHFPHLSFKDVRGNLNTRLAKLDAGDYDALILAV
AGLKRLDMSDRIHQILPPEISLHAVGQGALGIECREDDQEVLELLNAIAHPPTAQRCYAE
RSLLRALEGGCQVPIGVDTQLEGNTLTLTAIVASVDGQKLVKDTIQGEQSQAENLGLELA
EQLKKQGAQEILAEILAQIERE
>F4XML4|hydroxymethylbilane synthase|EC 2.5.1.61|Moorea producta 3L|TrEMBL
MTSTVTSPARTIRIGSRKSQLALIQTYWVQEQLKKHFPDREFEVQTMSTHGDKILDVALS
KIGDKGLFTKELELGMLRDEIDFAVHSLKDLPTRLPEGLVLGCVTERENPADALVMHQKH
LDKQIETLPEGSIIGTSSLRRLAQLRYHFPHLSFKDVRGNLNTRLAKLDAGDYDALILAV
AGLKRLDMSDRIHQILPPEISLHAVGQGALGIECREDDQEVLELLNAIAHPPTAQRCYAE
RSLLRALEGGCQVPIGVDTQLEGNTLTLTAIVASVDGQKLVKDTIQGEQSQAENLGLELA
EQLKKQGAQEILAEILAQIERE
>F4XML4|hydroxymethylbilane synthase|EC 2.5.1.61|Moorea producta 3L|TrEMBL
MTSTVTSPARTIRIGSRKSQLALIQTYWVQEQLKKHFPDREFEVQTMSTHGDKILDVALS
KIGDKGLFTKELELGMLRDEIDFAVHSLKDLPTRLPEGLVLGCVTERENPADALVMHQKH
LDKQIETLPEGSIIGTSSLRRLAQLRYHFPHLSFKDVRGNLNTRLAKLDAGDYDALILAV
AGLKRLDMSDRIHQILPPEISLHAVGQGALGIECREDDQEVLELLNAIAHPPTAQRCYAE
RSLLRALEGGCQVPIGVDTQLEGNTLTLTAIVASVDGQKLVKDTIQGEQSQAENLGLELA
EQLKKQGAQEILAEILAQIERE
>F4XML4|hydroxymethylbilane synthase|EC 2.5.1.61|Moorea producta 3L|TrEMBL
MTSTVTSPARTIRIGSRKSQLALIQTYWVQEQLKKHFPDREFEVQTMSTHGDKILDVALS
KIGDKGLFTKELELGMLRDEIDFAVHSLKDLPTRLPEGLVLGCVTERENPADALVMHQKH
LDKQIETLPEGSIIGTSSLRRLAQLRYHFPHLSFKDVRGNLNTRLAKLDAGDYDALILAV
AGLKRLDMSDRIHQILPPEISLHAVGQGALGIECREDDQEVLELLNAIAHPPTAQRCYAE
RSLLRALEGGCQVPIGVDTQLEGNTLTLTAIVASVDGQKLVKDTIQGEQSQAENLGLELA
EQLKKQGAQEILAEILAQIERE
>D0K5P1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus (strain ED98)|TrEMBL
MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>G7RSV5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain 'clone D i14')|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>F8L6H7|hydroxymethylbilane synthase|EC 2.5.1.61|Simkania negevensis (strain ATCC VR-1471 / Z)|TrEMBL
MIITVGLRDSKLSRKQLDELIHLFSSEYEFQPTYLQTIGDRQLDVSLRNMDKTDFFTRDI
DAIQLAGKVRISLHSAKDLPEPLPKGLMMVALTKGQDPSDSLVFREGENLETLPSGALVG
SSSPRRDKIVQTLRPDLLCVEVRGTIEKRLEKLFQGEIDALVVAEAALIRLELTYVNRIS
LPGPVAPLQGQLAVLAREGDHEMAKLFASLDSRRHNPGKKMAETTLYLGLDPSNFKTENT
LIHCPIIQIFPRDFNLPQIQYVFDDIPKYTHFIFTSKVGVNVFFDCLAHYQYGIDILEGK
EIIAIGESTAKAARARGAHVTQVAKEETQEGIIRMLAVQNLDHAFVFLPCSALSRPDLAH
FLMIKRIRHQLCKLYDTRAVELKNRPALEEIDEIVFTSPSTVDAFKKIFGEIPKNKKLIP
IGPITQSKLNSVFTF
>G0CVW3|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium ulcerans (strain BR-AD22)|TrEMBL
MTFTIGTRGSLLATTQSGHVRDALATHGYSAELSIVTTPGDVNMAPVERIGVGIFTQALR
EVLVEGGCDIAVHSFKDLPTQRDPRFHLIVPERADARDCLVARDGLTLEKLPQGARIGTG
APRRISQVKALRPDVECVPLRGNIDTRMGKVFSGELDAVVLAYAGLSRVGRGDEATEVFN
PDRFLPAPAQGALAIECRIDDAAAIAAINSIRDVDDETCALAERVVLNRLEAGCTAPVAA
HSVISGQELHVTGAVVSLDGRKVLRTTMTGAVTEAVAIGEAVAAKLIRDGAAEVLS
>C7MT07|hydroxymethylbilane synthase|EC 2.5.1.61|Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)|TrEMBL
MTNPSSRTLRIGTRASNLAMSQTRTIAKMLEEAGQKVELVPVSTPGDRSSAPIAEIGVGV
FTSALREALLANEVDVAVHSYKDLPTAPQPGIVLAAVSKREDPRDVLISRDGLTLGELPP
GAKVGTGSPRRMTQLRALGLGLEIVPIRGNIDTRIAKVTSGELDAIVLAKAGLTRVGKLD
LITEVIDPMQILPAPAQGALAVETRVDDVDTEHLLRSIVDHEATRVAVAAERAVLATLQA
GCSAPVGALAEVVEDLDSEGAVVERLSLRGVAATATEGDSVQILRASGVADKHEADRLGR
TVASELLDLGAGALSR
>B0UJC5|hydroxymethylbilane synthase|EC 2.5.1.61|Methylobacterium sp. (strain 4-46)|TrEMBL
MAHRPLRIGTRGSPMALAQTGMVRDRIAAAHPHLAEPGAMELVVVNTVADRILDRPLSAI
GGKGLFTKELEQALFAGEIDVAVHSMKDVETWLPDGLVIACILERDDPRDAFLSLASGSL
AELPAGARVGTSSLRRGAQVLMRRPDLRIVPLRGNANTRIRKLEEGVCDATLLAIAGLER
LGLAHLARTVIPVEEMLPAVAQGALGIECRAADEDVIALLQAVACPRTTTALAAERGLLA
ELDGSCRTPIAALAQIDGDRLTLDGLLFLPDGSAHWATTRSGPAAEAASIGREAGADLKA
QAGETYRRHLQ
>Q6LYW3|hydroxymethylbilane synthase|EC 2.5.1.61|Methanococcus maripaludis (strain S2 / LL)|TrEMBL
MKLRIGTRGSTLAMVQTEYIAGLLNDLDIETEIIIVKTTGDKDQNKKLADLGIGVFTKEL
DNKMLENEIDIAVHSLKDVPTLWSDELQITATPKRESPDDIIIWRKDCDFDIEHDELNVG
TSSIRRTSFLQFTNPNLTPKLLRGNVATRINKLRNGEYDTIVMAKAGLIRQGIDLSEFNY
KKLDILPAPAQGVIGVASRKADAKINQILEKICDKKTYIEATAERWALKEYGGGCQAPFG
AFAIYDTEEGILNLRCELVDEQGTIKRVKSNEGFVICTTDDVELSKELGARVGASFKEIE
TFTY
>B1GN25|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus anthracis str. A0465|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAVNKGQQ
>I2GTJ5|hydroxymethylbilane synthase|EC 2.5.1.61|Fibrisoma limi BUZ 3|TrEMBL
MHIKIGTRGSQLALWQAEYIQRLLQAGGLTSELVLIETKGDQIQDRSLAKIGSKGVFTQE
LEDQLRAGSIDIAVHSAKDLQSSLPTDLGIIAFTEREQVNDVLVSRNRNLSLTSGQSFVI
GTSSTRRVAMLKHFCPHIRVVDMRGNLQTRLRKLDEGQCDALILAYAGVHRMQYDDLIVE
HLPVKDFTPAVGQGSVAIEAAHTLAPDKLRIIRQLTNHEPTEACLKAERGFLRRLEGGCS
IPVFALATIENAQISLTGGLISLDGQQLLRETFTAPAAQAEQLGHELAESILARGGDEIL
RSIHEHLP
>A1WGQ9|hydroxymethylbilane synthase|EC 2.5.1.61|Verminephrobacter eiseniae (strain EF01-2)|TrEMBL
MSRTRPSPIVIATRASRLALWQAGHVQALLQARGHSVQLLGMTTRGDQILDRSLSKVGGK
GLFVKELEAALAEGRADIAVHSLKDMPMELPAGFALACVLEREDPRDAWVSPQYATLEAL
PPGAVVGTSSLRRQALLQALRPDLRMEPLRGNLDTRLRKLDAGQYQAIVLAVAGLKRLGL
EARIRAPFAPAALLPAAGQGALGIEVRSERQDLCAALAALAHQPSWLAVAAERAVSRAMG
GSCSMPLAAYGQFHGAVLQLDAAWGDPQGQAPLVRAQASATVTTLAQAEALGSALARRLC
ADGARPLVPVHDPAHGLVHDPVHDLAHDLGHDLGHTPADGLSHRR
>D0CLH7|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. WH 8109|TrEMBL
MALTELRIASRRSQLAMVQTNWVKAELEKAHPGLKITVEAMATQGDKILDVALAKIGDKG
LFTKELEAQMLVDRADIAVHSLKDLPTNLPEGLMLGCITEREDPADALVVNTKNHAYKLD
TLPEGSVVGTSSLRRLAQLRHHYPHLIFKDVRGNVITRLEKLDNGDYDCLILAAAGLGRL
GFGDRIHQLIPGDISLHAVGQGALGIECVEGKPEVLEAIKVLEHTPTSQRCLAERAFLRE
LEGGCQVPIGVNTRFEGDQLILTGMVASLDGKRLIRDQASGAASDAEAIGIALANTLKGQ
GAGEILKEIFDTVRPEA
>H4BZQ2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CIGC341D|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>Q4FNV7|hydroxymethylbilane synthase|EC 2.5.1.61|Pelagibacter ubique (strain HTCC1062)|TrEMBL
MKNRKIIIGSRGSKLALIYAEKAREKILKHSKDFGIEEVIIKEIVTKGDQVQDKRLSEVG
GKGLFSKTIEVELLEKKIDIAVHALKDMPSEETRGLLTDCFLERNDPREILISKDNKHLK
DLASNSIIGTSSYRREFQIKKIRDDLNCKLIRGNVDTRIRKLKENLYDAIILSYAGIDSL
GLNQNISQTFSTSEIIPCAGQGVIALQCRDNDESLIELLKQVDHQSTHSSIKAERNVLKV
LEGDCETAVGAFANIEGNKINLEVELFSLDGSKRFYLKSSESVNKAEELGIEMGKTLKKM
SNNSYKK
>F3VD25|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella dysenteriae 155-74|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D7VVA5|hydroxymethylbilane synthase|EC 2.5.1.61|Chryseobacterium gleum ATCC 35910|TrEMBL
MKSIRIGTRNSALALWQAREVARHLQNNNYLTEIVPIVSSGDKNLNQPLYSLGITGVFTR
DLDIALLNDEIDIAVHSLKDVPTQLPQNIEMIAYLERDYPQDILIRKESSRNKEFHELKL
ATSSLRRRAFWLRNYPTAEFSDIRGNIQTRLQKLEEGDFDATILSLAGIKRMKMEIDYEM
LPLMISAPSQGVISVAGHTDKPEINEIVRQINHQETQICVEIERNFLSTLEGGCTAPIGA
FAEIIGDQIRFKAALCSLDGKNCIAVDENFVYTPAENFGEKYAKVVLENGGKELMAEIKS
QI
>G2G483|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces zinciresistens K42|TrEMBL
MTQQALRLGTRRSRLAMAQSGQVADAVSRTTGRPVELVEITTYGDVSREALAQIGGTGVF
VTALRDALLGGEIDFAVHSLKDLPTTQPEELALAAVPEREDPRDVIVAREALKLTDLPRG
ARVGTGSPRRTAQLNAYARGHGLDIEMVPIRGNVDTRIRYVRDGGLDAVVLAAAGLSRIG
RLDEVTDFLSVDTVLPAPGQGALAVECSAGNADLVAALGELDDPFTRIAVTAERSLLAAL
EAGCSAPVGALADILVGGQVVKEMRLRGVVGTTDGTRMVQLSTTGPVPETHDRALTLGRE
LASEMLAQGAAGLMGERAQ
>G2G483|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces zinciresistens K42|TrEMBL
MTQQALRLGTRRSRLAMAQSGQVADAVSRTTGRPVELVEITTYGDVSREALAQIGGTGVF
VTALRDALLGGEIDFAVHSLKDLPTTQPEELALAAVPEREDPRDVIVAREALKLTDLPRG
ARVGTGSPRRTAQLNAYARGHGLDIEMVPIRGNVDTRIRYVRDGGLDAVVLAAAGLSRIG
RLDEVTDFLSVDTVLPAPGQGALAVECSAGNADLVAALGELDDPFTRIAVTAERSLLAAL
EAGCSAPVGALADILVGGQVVKEMRLRGVVGTTDGTRMVQLSTTGPVPETHDRALTLGRE
LASEMLAQGAAGLMGERAQ
>B5GQ15|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)|TrEMBL
MTERALRLGTRRSMLAMAQSGQVAQEVRRLTGRPVELVEITTYGDISREQLAQIGGTGVF
VAALREALLRGEVDFAVHSLKDLPTGQPDELALAAIPRREDPRDVLVARDGLTFDRLPDG
ARVGTGSPRRMAQLNAYARAHGLRIETVPIRGNIDTRIGYVRSGKLDAVVLAAAGLNRIG
RADEVTDVLSVDSVLPAPGQGALAIECAAADADLAATLGALDDPHTRVAVTAERSLLAAL
EAGCSAPVGALADLLGDEEVVTEMRLRGVVGTTDGSTLVQLSTTGPVPTSHGDAIALGRE
LASEMLAKGAAGLMGERAL
>B8JHA2|hydroxymethylbilane synthase|EC 2.5.1.61|Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)|TrEMBL
MIRIATRRSPLAKWQANHVSQLLRDREPGLEVRLHELVTRGDKILEVPLADVGGKGLFVK
EIEDALLNRDAEVAVHSMKDLPAVLAPGLVLAAVPQREDPRDALCSPRWKTLAALPKGAR
VGTSSLRRSAQLKALRPDLQMEMVRGNVETRLRKASEGLDAVVLAYAGLRRLGLAEHATY
VFPPEEMLPAVAQGALALEARADDAPTLARLAALEDPDTRVRIEAERGFLARIEGGCQVP
IAGHATLAGGKVTIRALVASLDGARVIRGERTGAYAEARAMGESLADELLSRGADQILRE
TEGKAPGLAAPKRG
>E8T1M3|hydroxymethylbilane synthase|EC 2.5.1.61|Geobacillus sp. (strain Y412MC52)|TrEMBL
MRNIVVGSRRSKLALTQTKWVINELKQLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLF
VKEIEHELLAGGIDMAVHSMKDMPAVLPEGLVIGAVPRREDARDVLVSKGNRMLSDLPPG
SVIGTSSLRRSAQLLAYRPDLTIKWIRGNIDTRLAKLESEEYDAIVLAAAGLARMGWGDD
VISDYLPFDVCVPAVGQGALAVECREDDDELRQWLSRLNDEQTERAVRAERAFLQQMEGG
CQVPIAGYAEADGGMVRLTALVASPDGKEKYKEMVTGADPEAVGRQAAAVLIEQGAKALI
ERVKQELSQS
>H6LI57|hydroxymethylbilane synthase|EC 2.5.1.61|Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655)|TrEMBL
MKIKVGTRGSMLARTQSQWLIDVLAKAHPQINFEMVIIKTKGDLVQDKPLDKIGDKGLFT
KELEDALLSGEIHMAIHSMKDMPSKLPEGLVLTVPTIREDPRDVLLTPHHISSLEELPEG
AVVATGSKRRICQIKKLRPDIELIGIRGNIDTRIRKMQEQKLDGIVLAAAGLKRIGRFED
SAYQTVSLPENMFVPAPAQGILAVEIRADNQQVKELMAAISDKNTRIQMQAERSFLETLN
GSCHIPVGAFCEIKDQTIVLYGLYGLEDGSRVVTQSIEGSPEEAENLGKQLAKKCYAAVH
QQTGKVYLAGGGCGDPGLLTVKAREILEKADVVVYDALVNERFINDARADAEIIYVGKRA
GNHAMRQEDINALLVKKGQEGKLVLRLKGGDPYVFGRGGEEGEDLYDAGVPFEVIPGITS
VIGGLAYAGIPITHRDCVSSFHVITGHLKSNAYDGSSDLDWPVLGKLKGTIVFLMGVKNL
EKICAELVKNGMNPDMPVAVVHRASTPYQRVVTGNLKTIYEIATNEKITAPSLIVVGEVV
NKRQKLRFFDQKPLFGKNIIVTRSREQSSQMVEKINELGGNAIEFPTIRIIPINEAACDQ
KVDVLSDYSHIIFTSINGVEIFFDSLTRCGKDARAFGKLHITAIGEGTKKALQQRCLRAD
FVPDKYVGEELVNGLAPLLNKNSRVLIPRSKNARIYVVEELSKICPVDEVQTYETVREDH
ATENPLEMLEAQKIDYITFTSSTTVQFFVDKIGAEHIDAINTAKAVSIGPQTSKKCRELG
INVNIEAEPYTIQGIVDAILKDSQK
>I6HZ99|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis PY-19|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>Q2JFS0|hydroxymethylbilane synthase|EC 2.5.1.61|Frankia sp. (strain CcI3)|TrEMBL
MTGIDPTSTDPTSTDPTSIGATGTGATGTGADLLARFAGRRLRLGTRRSALALAQSGTVA
ATLRARVGCAVELVPIVTAGDRSSGEISQIGGTGVFVSALRDALLSGEIDLAVHSLKDLP
TATPPGLVLAAVPPRADPRDVLVAPSGRRLAELRAGARIATGSPRRAAQLRALGLGLEVV
TIRGNVDTRLKKAIDGEVDAVVLAHAGLARLDRLDAVTEILEPTVMLPAPGQGALAIECT
GGAGLVVAGPARALVPAGPGSGPAVGQTGGETWSDGGQPVDTGLAELLRFVLDDASSSVA
VRAERAFLAGIEAGCTAPVGALAELLPELAEGAAAEAGGAPPAGRLCLRAVVAAPDGSDV
LRRDVTGSAVDPEALGQRLADDMLSAGAHSLMGTR
>H3T9G9|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa MPAO1/P2|TrEMBL
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAE
AILEAVYGEAGHP
>E0QFZ8|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli JV20|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>Q3IF72|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas haloplanktis (strain TAC 125)|TrEMBL
MTQTTNIVRIATRKSALALWQAEFVKAQLEHYHPGILVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLEGLADMAVHSMKDMPVEFPEGLTLHTICEREDPRDAFVSNNFANIDE
LPQGAIVGTSSLRRQCQIRASRPDLKIHDLRGNVNTRLAKLDSGQYDAIILAAAGLIRLE
MKDRIRAYIEPEVSLPANGQGAVGIECRTDDEAIKALLAPLEHSETRIRVNAERAMNRHL
EGGCQVPIGAYALVNGDQVHLRGLVGAIDGSEILRDEVSGHVNDAEKLGVELAKMLLAQG
ADRILAEVYRDA
>I5SA95|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW09195|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>I4ZG32|hydroxymethylbilane synthase|EC 2.5.1.61|Enterobacter cloacae subsp. cloacae GS1|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKQRLEACHTGLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELELALLENRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNRYDSLDALP
AGSVVGTSSLRRQCQLAERRPDLVIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLELE
ERIRVALPPELSLPAVGQGAVGIECRLDDVRTQALLAPLNHDDTAVRVKAERAMNTRLEG
GCQVPIGSYAELTDGELWLRALVGAPDGSHMVRGERRGKPQDAEALGVSLAEELLNNGAR
EILAEVYNGEPPA
>C7LEB5|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella microti (strain CCM 4915)|TrEMBL
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAG
LRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>F9ICD3|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter baumannii ABNIH1|TrEMBL
MLEFMKTLKIATRQSPLALWQAEHIRARLQELHPDLTVELVKFVTQGDKILDTPLAKIGG
KGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLTLAVICEREDPLDAFVSNQFEKFAD
LPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAGLKRLG
LAERIRHCIEPSVSLPAVGQGALGLECRADDQEVLTLIQPLLHPETDVCVRAERAFNAYL
EGGCQVPIAGYATLQDGKIHIEGRVGSVDGQTLLRAELTDEANNAQQLGENLARNLLDQG
AGDLLKALY
>G2M308|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori Puno120|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLERAFVKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEAFLQSGAKEIL
EKAQLF
>D5X258|hydroxymethylbilane synthase|EC 2.5.1.61|Thiomonas intermedia (strain K12)|TrEMBL
MTSTFTPPPSLVIATRESRLALWQAEHVRDLLKGLYPQCDVRIFGMTTQGDQILDKSLAK
IGGKGLFVKELEVAMEQGHADLAVHSLKDVPMVLPTGFALTAVMEREDPRDAWVSPHYAN
LADLPAGAVVGTSSLRRESQLRARYPHLKVQALRGNLDTRLRKLDEGQYAGILLAAAGLK
RLGLGERVRAVIEPEDMLPAVGQAALGIEIRADRPDLAQALAALNHPPTALCTHAERAVS
RGLGGSCTTPMGAYATLEGEAMHLRAVLGLPDGSQALHAQQRGRVTDLAQAEALGQQVAR
QLREQGADALLAQLGSH
>B2H3B6|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei 1655|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAALMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>H3VXE5|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU125|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>G8NVP0|hydroxymethylbilane synthase|EC 2.5.1.61|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MTIPTIRIGSRGSQLALWQANHIAAQLRERGHAVEIEVIRTVGDRMQDPGFVAPATFPDG
TSLDAKGIFIKEIEDTLAVGKIDLAVHSLKDLPTTLDPRFTLAAIPVRADARDAFVCESY
WGLHMLPSGARIGTTSPRRQAMLLALRPDLEFVEMRGNIDTRLRKWSEGQADALVLASAG
LDRIGRAENVHQRFSIDELTPAPGQGALALETRCPLHPLDTEDSSRDPAIYAAIRELNDS
ATEYAVQAERTVLAVLGGGCQLPLGAFCHAVDDQWHLHAMVVSPDGEQVAHVVQKVPFGT
PACELGSAVASELTARGALELLQVQPVA
>I2NK82|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus paraphrohaemolyticus HK411|TrEMBL
MKDTLRIATRQSPLALWQANFVKAELEKHFPELNVELVTMVTKGDIILDTPLAKIGGKGL
FVKELELALLENRADIAVHSMKDVPMSFPEGLGLAVICEREDPRDAFVSNHYANLDELPS
GAVVGTSSLRRQCQLMAKYPHLTVKSLRGNVGTRLSKLDNGEYDAIILASAGLIRLGMPE
RIKSFISVEQSLPAAGQGAVGIETRINDERILNYLAKLNHETTACCVKAERAMNTRLQGG
CQVPIGGFATIENGEITLNALVGALDGSSIIQATGKAPVSEAEQLGVKIAEQLLAQGADK
ILAEVYAE
>I4AJ53|hydroxymethylbilane synthase|EC 2.5.1.61|Flexibacter litoralis DSM 6794|TrEMBL
MAKTTIKIGTRNSQLAMWQAKHVQHLLESHGLATEIIAIETKGDKILHKAISKIGSKGVF
TEELEDMLHTGKVDLAVHSAKDMASTLPNGLELIAYTQREKPHDVVVSYNSDFKLDAADK
WLVGTSSTRRIAMLKHYHPNIRTTNMRGNLQTRMRKLEEGQCDALLLAYAGVHRMGFEDY
IVEHLPLNEFTPQAGQGSMTIEVSNKISNELRETIRKIINDEQTEYCLLAERAYLKHLDG
GCSIPSFVLAKLEGDMLQIDAGLISLSGKKIIRKSGKIHKDEGQKLAIELAQKVLEAGGD
KILARIKSKN
>G2KS96|hydroxymethylbilane synthase|EC 2.5.1.61|Micavibrio aeruginosavorus (strain ARL-13)|TrEMBL
MAQKLRIGTRGSKLALVQTTMVADGLKAAHPGLDVEIVVIQSSADWKPEQGETRLSEAEG
GKGLFAREIEQAILAGAVDCGVHSMKDMASFLPEGLQVVHVLDRADPRDALLAHDGIKAI
ADLPQGAVVGTASLRRQAMLLAIRPDLKIVPLRGNVPTRIEKLRSKQVDATILALAGLNR
LGLAHEASCTIDADTMLPAAGQGIVGIETRVGDTQTMALLDAIHNRETGLVLAAERAALQ
VLDGSCHTPIGAHATLNGDQLHLRVLVASGDGVQVFTDEQSGPVHVDHDAALIGQVVGAR
LKSRLPDGILQ
>E3HEG9|hydroxymethylbilane synthase|EC 2.5.1.61|Achromobacter xylosoxidans (strain A8)|TrEMBL
MSLPQRLVIATRASRLALWQAEHVRDRLRTLYPACAVELLTLTTRGDQILDRTLSKVGGK
GLFVKELENALLDGRADLAVHSLKDVPVDLQAPFELCAVLDRADPRDAFVSNTHDTLADL
PAGAVVGTSSLRRESQIRARYPELVVKPLRGNLDTRLGKLDKGEYDAIVLAAAGLERLGL
GARIRSLLEPEDSLPAAGQGALGIEIRDDRDDMRAWLAPLVSADTTSCVVAERAVSRKLG
GSCQVPLAAYAEIAGGTLSLRALVASPDGVRMVHASRSGPVADAQAIGEAAAQALLDAGA
QDILRELLQDEPRPD
>B3BG95|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC869|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>E1WE00|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella typhimurium (strain SL1344)|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHS
LDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELL
ENGARAILTEVYNGETPA
>B1XNS5|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)|TrEMBL
MTAETPSKRTVRIGSRKSQLALVQTYWVRDELQKAYPEITFEVQTMETQGDKVLDVALSK
IGDKGLFTQELEDGMLKGETDFAVHSLKDLPTNLPEGLMLGCVTERVDPADALVVNEKHR
DKKLETLPSGSVIGTSSLRRLAQLRHHFPHLEFKDIRGNVNTRLAKLDRGEYDAIILAAA
GLQRLDFGDRIHQIISSDISLHAVGQGALGIECRDGDEEILGLLRPVLEHAESRDRCYAE
RSFLRQLEGGCQVPIGVNTTIEGDRLTLVGMVASLDGQTLIRDEVSGSRADAEKLGIELA
QKAIAQGADKILAEINEANRA
>G4T2L1|hydroxymethylbilane synthase|EC 2.5.1.61|Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z)|TrEMBL
MANQIIRIATRKSPLALWQAEHVADRLKRAFPGLETELVTMTTKGDKLLDAPLAKVGGKG
LFVKELEQGMLEGRADIAVHSMKDVPVEFPDGLHLSVILQREDPTDAFVSNHYASLSELP
ERPRIGTCSLRRQCQIKEKFPNAEILTLRGNVNTRLAKLDAGEFDAIILASAGLVRLEMQ
HRIAARLDPSESLPAIGQGAIGIECRSDDTVINELLSRLHDPETHICVSAERAMNARLKG
GCQVPIAGFATLQSDILYMRGLVGDPDGSVIYRAERSGSAEQAEQIGVSIAEELLASGAD
KILQALF
>C3JK04|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus erythropolis SK121|TrEMBL
MSVTTPRSGSPLRIGTRGSLLATTQAGTVRDALIAAGHPAELVIIKTKGDQSTDPVQKIG
VGVFTAELREALVDNRVDVAVHSYKDLPTAQDPRFVIAAIPPREDPRDALVARDGLVLGE
LPAGSKVGTSAPRRVSQLKALGLGLDIVPLRGNLQRRLGKVESGELDAVILARAGLSRIG
LLDLITENIEPVQMLPAPAQGALAVECLSANAELAAILAEHDDAGTRAAVTAERALLAGL
EAGCTAPVGAIAEIVESLDDDGRIFDELSVRGCAAAIDGSDVIRTGAVGAPDKAEELGRA
VARELLELGARELMNVTTGEAADV
>C3JK04|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodococcus erythropolis SK121|TrEMBL
MSVTTPRSGSPLRIGTRGSLLATTQAGTVRDALIAAGHPAELVIIKTKGDQSTDPVQKIG
VGVFTAELREALVDNRVDVAVHSYKDLPTAQDPRFVIAAIPPREDPRDALVARDGLVLGE
LPAGSKVGTSAPRRVSQLKALGLGLDIVPLRGNLQRRLGKVESGELDAVILARAGLSRIG
LLDLITENIEPVQMLPAPAQGALAVECLSANAELAAILAEHDDAGTRAAVTAERALLAGL
EAGCTAPVGAIAEIVESLDDDGRIFDELSVRGCAAAIDGSDVIRTGAVGAPDKAEELGRA
VARELLELGARELMNVTTGEAADV
>G2SG04|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodothermus marinus SG0.5JP17-172|TrEMBL
MPEPTLILGTRGSALALRQATLIRSFLEARGVSVQVEIIRTTGDHIQDVPLAKIGAKGLF
TKELDQALLEGRIDLAVHSLKDLPTEMPEGLVVAAVPERAPPWDVFVAHPDFAGRLEDLP
TGAVVATSSLRRQAQLRAWRSDLQVVPVRGNVDTRLRKLEAEGWHGLILAEAGLQRLGLL
ERVRQRIAPEILLPAVGQGALGVVCAEANRRVRALLQALHHAPTAAAVRAERALLHALQG
GCQVPVAALAAVEADGTLVLRGRVVSLDGRQVVEGVERGPMAEPEAVGKALAEKLLKQGA
RAILEEIRGQHP
>H4KPF7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC2C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNTYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A4VGX9|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas stutzeri (strain A1501)|TrEMBL
MPMSREIRIATRKSALALWQAEYVKARLEASHPGLKVSLVPMVSRGDKLLDAPLAKIGGK
GLFVKELETALLENEADIAVHSMKDVPMEFPEGLGLYCICEREDPRDAFVSNRFDSLDAL
PPGSVVGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGF
GERIRSSIGVDESLPAGGQGAVGIECRTGDSEVHALLACLNHAPTATRVVAERALNKRLN
GGCQVPIACYAVLEGEQLWLRGLVGQPDGTLLLRAEGRAPAAEAEALGVQVAEELLDQGA
EQILKAVYGEAGHA
>C4KSQ9|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei MSHR346|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDALVAASAQAQKGGA
>C8TL15|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O26:H11 (strain 11368 / EHEC)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H0FJ53|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus amyloliquefaciens IT-45|TrEMBL
MRTIKVGSRRSKLAMTQTKWVINKLKELNPSYDFEIREIVTKGDRILDVTLSKVGGKGLF
VKEIEQALLHQEIDMAVHSMKDMPAVLPEGLVIGCIPKREDPRDALISKGHQKLDGIKEG
GIIGTSSLRRSAQILAERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKDD
VVSEFLEPDRCLPAVGQGALAIECRESDEELLKLFAQFTDEYTQRTVAAERAFLHAMEGG
CQVPIAGYASVNDRDEVELVGLVASPDGKTIYKETAAGHDPEEIGKRCAAMMSEKGAKAL
IDSVKQELEQDGK
>F6IIR8|hydroxymethylbilane synthase|EC 2.5.1.61|Novosphingobium sp. PP1Y|TrEMBL
MAHDKQDMKLRLGTRRSPLAMAQAEEARDRLAAAHGIDPAHIEIVAVTASGDRIQDRALA
EIGGKALWTKELDAWLAAGEIDFAVHSAKDVETIRPDAFAICAVLPRADVRDVLIGADSI
HALPPGAVVGTSAPRRAAQLLHARPDCSVITFRGNVATRLAKLAAGEADATFLAAAGLER
LGQTGTGHPLAEDEWLPAPGQAAILIECRADDARTHEILSAIDDAPSRSAVMAERALLAS
LGGNCHSPIAVLTRLEGDRIVLRAALYSPDGAEKVEGEIRFAASDLEAPARLGADLLSRA
VPAIAAHFDGPA
>Q1V613|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio alginolyticus 12G01|TrEMBL
MTQSTPIRIATRKSPLALWQAYFVKDALQAAHPSLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEIAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSHIDEL
PQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EERIRSFIEPEQSLPAVGQGAVGIECRLDDERLLKLLEPLNHQDTVDRVLCERAMNLTLE
GGCQVPIGSYALLDGDNIWLRALVGEPDGSEIVRGEIRGHRKDGEALGVQLANELLDNGA
REILTKLYADHE
>A4AF09|hydroxymethylbilane synthase|EC 2.5.1.61|marine actinobacterium PHSC20C1|TrEMBL
MAQTTTVARALESKTGVETEIIPISTQGDRSTESLSTIGGQGVFANALRDALLAGECDVV
VHSLKDLPTAEVPGLTIAAVPKRADERDVVCARDGLTLETLPAGARVGTGSPRRQAQLRS
LYPDLEVVDLRGNIDSRLDKVTDGHLDAVILAAAGLARAGRSDAVTEHLGIAGWPTAPGQ
GALAIETRTGEEKLAAVLDHKPSRTKTDAERYVLAFLDAGCSAPLGAHAVIDDGLLFLDA
RVYALDGSRYLTSSHALYVNDVEDPAREAAQRVADELLAQGAGDLTGARA
>A4AF09|hydroxymethylbilane synthase|EC 2.5.1.61|marine actinobacterium PHSC20C1|TrEMBL
MAQTTTVARALESKTGVETEIIPISTQGDRSTESLSTIGGQGVFANALRDALLAGECDVV
VHSLKDLPTAEVPGLTIAAVPKRADERDVVCARDGLTLETLPAGARVGTGSPRRQAQLRS
LYPDLEVVDLRGNIDSRLDKVTDGHLDAVILAAAGLARAGRSDAVTEHLGIAGWPTAPGQ
GALAIETRTGEEKLAAVLDHKPSRTKTDAERYVLAFLDAGCSAPLGAHAVIDDGLLFLDA
RVYALDGSRYLTSSHALYVNDVEDPAREAAQRVADELLAQGAGDLTGARA
>I6BC11|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri CCH060|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A7HST6|hydroxymethylbilane synthase|EC 2.5.1.61|Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)|TrEMBL
MQRRYRIGTRGSRLALIQANEVARRIALALHAPVEEVTEIVVISTAGDRVQDRALSEIGG
KGLFTEEIEEQLADARIDVAVHSMKDMPTLLPEGLVIDCLLERADPRDAFLSSKANSLMS
LPQGAVVGTSSLRRAAQVRARRPDVTVVPFRGNVDTRLKKLADGVADATLLAMAGLTRMD
LLECVTAPLSPEELLPAVAQGAIGIERRAADDEAAHLLEKLHHTETGLRVAAERAFLAVL
DGSCRTPIAALAEISGDHMRLRTMILTPDGAEIHETEREGLAADAVLLGQDAGEELKGRA
GPHFFDTV
>H5J8E5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC12B|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>E3PXF6|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654)|TrEMBL
MKIIVGSRGSQLALTQTKLIVNELSKLNPNVDFEIKVIKTKGDKIQDIPLDKMNDKGIFV
KEIEEQLISYEIDMAVHSMKDMPTKMDERLVFPVIPKREDSRDALILKNNLKLEDLSMLE
TMIIGTGSKRRSYQFKASYPKAEFEPIRGNIDTRINKLHTQNLDGIILAASGLKRISREN
EISHYFDEKTMIPAPCQGILALQTRTNDYQVIAVLSKVEDRCSRIQYIAERAYLEEIEGG
CHAPVGAYCEINGDKITIYAVYGDEQGNKLIRDNITGATDNADELGRTLAKKMKLALEES
YEKR
>I4IDX8|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis sp. T1-4|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELELGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSQNQD
YQLDSLPAGAVVGTSSLRRLAQLRYHYPHLTFKDVRGNVNTRLAKLDAGEYDGIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDGDAEVLQVLKVLEHAPSRDRCYAERA
FLRELQGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEVLGRDLAHK
VREAGAGEILAEIFAEVGR
>B8F5M3|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus parasuis serovar 5 (strain SH0165)|TrEMBL
MKEILRIATRQSPLALWQANFVKDALEQRFPQLSVELVTMVTKGDIILDTPLAKIGGKGL
FVKELELALLENRADIAVHSMKDVPMTFPEGLGLAVICEREDPRDAFVSNHYANLEALPA
GAVVGTSSLRRQCQLMAKYPHLQIKSLRGNVGTRLSKLDNGEYDAIILASAGLIRLGLSE
RIRTFIPVETSLPACGQGAVGIETRLNDERVLAYLAELNHQPTAYCVQAERAMNSRLQGG
CQVPIGGFATLTGDEIELNALVGSLDGSTIVRASAKGNIKEAEKLGVEVAEALLAKGADH
ILKAVYQSE
>H8NHK2|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia typhi str. TH1527|TrEMBL
MINSIRIGTRNSTLALIQTNLVIAQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDIPGRIPVDLVIAAVLEREDPRDVLVCLNYKSIETLPQ
NAVIGSSAVRRKAFIKKIRPDLNIKVFRGNVDSRIKKLMTGEVDATILSYAGLKRLNAFN
KKYCHLIEYSQILPCVGQGVIAVEIRKDDNAMFNICNQINHIPTFELIKPERAFLEHLDA
NCSTPIGAYSQYLDAYNIQTDFMLGKLDCNKIIFQTEITNINTSRECGIKAAKMMLAQQ
>F3ZW52|hydroxymethylbilane synthase|EC 2.5.1.61|Mahella australiensis (strain DSM 15567 / CIP 107919 / 50-1 BON)|TrEMBL
MNKIRVGSRGSRLALAQTDAVISALRSLYPDIDFERQIVKTEGDRLQHIPVERIGDKGIF
VKDIEQALMDGHIDMAVHSMKDVPSQLPDGLMIGAMPWREDPRDAFISSDGRTIEQLGCR
ARIGIGSARRSAQLKNCFPGIDIVAIRGNIDTRINKINEAGLDGIVLAVAGLKRLGVSDV
ITQILPVDVCTPAAGQGALGIEIRKSDEKAADLLMPLNHAPTRAAVDAERMFMAMMGGDC
NTPIGVYGEVDGVDILLRAAVEKDGCIMRHSVKGEVAQYQNVVSKLVALLEE
>F8D2Z7|hydroxymethylbilane synthase|EC 2.5.1.61|Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6)|TrEMBL
MRTRGTLRLATRGSTLARRQATLVKEALEDRRYEVELVTVETTGDQIRDELIHQLGKTGA
FVRELDERVLEGDLDGAIHSMKDMPTEQPDDLVTAAVPERGRPGDVLVTPDSSTLEELPE
GATVGTSSLRRRAQLLSERDDLQVEPLRGNVDTRLEKLLAPALQEEHQQRSEADKERKAN
TGDEDFEPAYDRTVDEWFDDLSELERQALGREVETEYDAIVLAHAGLERSGLAHYVDYQE
LPTSTFVPAPGQGALAVTATDGETARDIQSAIDHPRSRVETTVERTILAELGGGCIAPVG
IYAVVQGEYVHADVTVFDRDGEESVTGARDLPIERHAEAAREFARDLADRGAAELIERAR
EDAGADADDDTGAGDTDDTDGGSTGGVPSEDKPAGK
>E1E5I9|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus TCH70|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>A9AB71|hydroxymethylbilane synthase|EC 2.5.1.61|Methanococcus maripaludis (strain C6 / ATCC BAA-1332)|TrEMBL
MNLRIGTRGSTLAMIQTEYIAGLLNDLGVETEIIIVKTTGDKDQNKKLVDLGIGVFTKEL
DNKMLENEIDIAVHSLKDVPTLWSDELQIAATPKRESPDDIIIWRKDSDFDIEHDELNVG
TSSIRRTSFLQFTHPNLTPKLLRGNVATRIDKLRKGEYDTIIMAKAGLIRQGIDLSEFNY
KKLEILPAPAQGVIGVASRKADAKINEILEKICDKKTYIEATAERWALKEYGGGCQAPFG
AFANYDTEAGILNLRCELVDEQGTIKRVKSNEGFIFCNTDDVELAKELGARVGALFKEIE
TFTY
>D6YXX9|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar G (strain G/9301)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>E1FB47|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoanaerobacter sp. X561|TrEMBL
MKKVIKVGTRSSELALKQTAMVINEIKKFRQDFEFEIVKITTQGDALIDKPVSEIGGKGV
FVKEIESALLKGEIDMAVHSMKDMPYEIPKGLKLMAVLKREDPKDVFVSGDGTQFMDLKE
GAKIGTSSLRRQVQLKALKPDIQIVPIRGNVRTRLKKMEELNLDGIVLSAAGLHRLGLEN
IITEYFPPDVVVPAPCQGILAVEIAESFDNIFQEFYPYIVDRKTFFEASVERELLKAFGV
NCRQPFGAYAQYRKEEDEEKINIKVAYQKENKLLKSEVTGLIEETDKMIEKLIEEFGGI
>Q48QD7|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)|TrEMBL
MSCYYPSHSLSTDCSMSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRG
DKLLDSPLSKIGGKGLFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPR
DAFVSNTFASLDELPAGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYD
AIILAAAGLIRLGFENRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTA
VRVIAERSLNKHLNGGCQVPIACYAVLEGDDVWLRGLVGDPAGSVLLHAEARAPQTSAQA
LGVQVAEALLAQGAADILKAVYGEANNE
>F0J1B8|hydroxymethylbilane synthase|EC 2.5.1.61|Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / AIU301)|TrEMBL
MKMHQESSSGSKVAPHSGRRLPLRVGTRGSPLALRQTDMFLAALREICPALGFAPDAFAP
EIISTTGDRVTDRPLAEIGGKGLFAKEIHEALLDGRIDFAVHSLKDLETALPDGIILACT
MKREDARDALILADGLGPVNDGDIWSSLPKGARVGTSSVRRQAQLLHARPDLQIGLLRGN
VRTRLDAARIGTFDATLLALAGLRRLGFEEEVAAAIDPEAMVPAACQGIVGITVRAADSR
LAELLAAIENHEAKAVSKAERALLAALDGSCRTPIGGHARLLPDGNLHLTGLTARPDGSF
LLKRSEVANAADAARLGAELGASLRRDSPADIFLD
>C8NBV9|hydroxymethylbilane synthase|EC 2.5.1.61|Cardiobacterium hominis ATCC 15826|TrEMBL
MTANISEIRIATRESKLALWQAEHVAARLRAHYPHLAVRLVPMTTRGDQILDAPLARIGG
KGLFIKELEQAMARGEADIAVHSMKDVGVHLPEGFRIAAILPRENPHDAFVSNHYASLAE
LPPGARVGTCSLRRRMQLARLRPDLKLLDLRGNVQTRLDKLDRGDFDAIVLACAGLIRLG
LQARIRAELPPEQSLPAIGQGAIGIECHETSAVYPLLAALDDADTALCVHTERIINTHLE
GSCQVPLAAHAALHGERIHLAARIGMPDGSRYLSAADDAPRRDAEALGNHIAARLIADGA
RDILQTLSHE
>B0SNK5|hydroxymethylbilane synthase|EC 2.5.1.61|Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)|TrEMBL
MSETIKIGGRSSLLSRIQIHTVTNALKEKNKDLNFETIFRESSGDKDLTTPLWQFGGQGI
FTKDLQEDLLNHKVDIVIHSYKDMDLKERKETTLIPVLPREDVRDVLLFKKNKWINLPNE
ITILTSSPRREYHIKEFLRNYFPTPINNFEIKIESVRGNIQTRLRKYLDHESGGILVAKA
ALDRILNFQDPDQLLPELKEIQQLIKDTMNVSLFMVLPSSIFPSAPAQGALCAEIRKEDK
HLETLLSKISDSETNLTTNEEREILSRYGGGCHQKIGVTVLHREYGKVCFIRGITEDGQI
LQTKELSESPNYSFSRDEVWPPNAKMAARQRERLTYSIPKDVDVFVSRGYAFPLDLSVNP
SNQILWSAGLSTWKDLALRGFWVNGTCDGLGESEPPEIDTILGRKTKFVKLSHMDSDKHS
SIYPVIPTYFVSAPEIPIPFDTSKIKAAYWRSGSEFDIVTKRYPELLNVIHFVGPGSTFR
KIKHALGENGSKNKVFVSLSFDSWVERYIKP
>I2UC20|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 4.0522|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQNAEQMGISLAEELLNNGAREILAEVYNGDAPA
>F5K0E5|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas aeruginosa 138244|TrEMBL
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKG
LFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
SRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAE
AILEAVYGEGGHP
>E7SAV6|hydroxymethylbilane synthase|EC 2.5.1.61|Streptococcus australis ATCC 700641|TrEMBL
MRSIKVGTRKSQLAMTQTKMMVDRLKECHPDVEFELVPYKTQGDRLVHVSLQTIGGKGVF
VKEIEQALLNRDIDIAIHSLKDVPSILVDGCTIGAIPEREDVRDCLIYREEGMTLATLPQ
GAVVGTSSIRRQVQLQSLRNDLQFKPLRGNIDSRIRKLQEGECDAIVLAAAGLKRIGYLD
QSPSLNIEFLNPHEFIPAVSQGALAIECREDDEEVLEILASIHDKEVENCIQLERCFLSL
MNADCTFPVGAHAQYIDGHYHLETMLADAKDRCLYVALTSKDGSDLPKRALEQLMEKGAL
TDKWWEA
>I5XFB9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4448|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H0DUS6|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis 14.1.R1.SE|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSIIPDGLTLGCIPDREIPFDAYIAKNHIPLEELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDVLLPAIGQGALGIECRSDDKELLDLLTKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIVQDNQIEFTGLIMSPDGKERYEHTTLGSDPVQLGIEVSQVLKKQGAYDI
IKKLNEAE
>A6LKX0|hydroxymethylbilane synthase|EC 2.5.1.61|Thermosipho melanesiensis (strain BI429 / DSM 12029)|TrEMBL
MKIRVGTRKSKLALIQTQLVVNKLKELLPNIDFEITPVVTKGDRLKTPIDKIGGKGVFVS
DIEKLILDDKLDIAIHSMKDLPSKIPDKLFLTSVLKRECPNDVFIGKENFFNLKKGAKIG
TSSKRRALQINMLRPDIEIVPIRGNVDTRIKKIGELDGIVIAAAGVIRLGLKDKITNLFE
FEKIVPAPCQGILALEFSEKFLKPFEEIKDVIVDPKTEVETQIERKILSLLNFDCNTPFG
FYCDASKKVTCYMFKNNERKKFTFESPEIEKILGEIIWE
>B4WI98|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. PCC 7335|TrEMBL
MSSNVATRTIRIGSRKSQLALVQTHWVQAELSKAFPDITFEVSTMETQGDKILDVALSKI
GDKGLFTQELEDDMLSHRVDFAVHSLKDLPTQLPEGLMLGCVTEREDPADALVVHEKHKD
KQLDTLPEGAVIGTSSLRRLAQLRHHFPHFQFKDIRGNVNTRLRKLDEGEYDAIVLAAAG
LNRLDMSDRIHQLLPAEISLHAVGQGALGIECRSGDEDILTVIKALEHLPTAQRCYAERA
FLRELEGGCQVPIGVNTRIEGDTLTLVGIVASLDGQQLIKDTVQGAPADAESMGKELAER
LREQGAQKILDVINAENRS
>I3YUY4|hydroxymethylbilane synthase|EC 2.5.1.61|Aequorivita sublithincola DSM 14238|TrEMBL
MKKTIRIGTRDSELALWQANTVKSKLETLGYDTELVPVKSQGDLILDKPLYEMGITGIFT
KTLDLAMITGAVDIAVHSMKDVPTQLPKGIIQTAVLERASSEDILVVKDEIDFEKPCTIA
TGSLRRQAQWLHRYPNHKVVDLRGNVNTRLQKLENNNWQGAIFAKAGLQRINLLPENYID
LDWMIPAPAQGAMVIVALENDVFCREATLKLNHSPSEICTHIEREFLRTLEGGCTAPIGA
FAEIIEDEVLFKGCLFSLDGKSKLEIEKKILTSEYKNFGKDCATFILNNGGSELMHTIKN
ELK
>A5IAI6|hydroxymethylbilane synthase|EC 2.5.1.61|Legionella pneumophila (strain Corby)|TrEMBL
MIFTQRTYTVYSMSAKIIRIATRQSPLALWQANHVRKMLVKQWPNLSIELLPMITSGDRF
LKDKLLSAGGKGLFVKELEEALLDKRADLAVHSTKDMPAQLPDGLLLAAICKRDNPFDAL
ISPQFKSLDALPKNAIIGTSSLRRQSQLLAYNPNLQIKTLRGNIHTRLSKLESGEYQAII
LAAAGLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIHGLNDPISALCV
HTERRVNAKLGGNCHIPFAVYCTITEEKRLLLRAKVLNMDGSQMIDDEQQGKIAEAEVIA
DRCTESLMTKGAMSLLSTIPS
>B3XGG3|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 101-1|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDN
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>A2P8B5|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae 1587|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGNTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>G7FQ85|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudoalteromonas sp. BSi20480|TrEMBL
MTEKTKLVRIATRKSALALWQAEFVKAQLEHFHDDVRVELVPMSTQGDIILDTPLAKIGG
KGLFVKELEQAMLDGRADIAVHSMKDVPVEFPEGLALHTICEREDPRDAFVSNHFANLNE
LPEGAVVGTSSLRRQCQIRALRPDLEIRDLRGNVNTRLAKLDAGQYDAIILAAAGLIRLE
MGERIADYIEPEVSLPANGQGAVGIECRIEDEVTKALLAPLEHTHTRIRVNAERAMNRRL
EGGCQVPIGAYALVDGEQVHLRGLVGAVDGSEILRDEVAGHINDAEKLGIELAEKLLAQG
ADKILADVYRDA
>H7WQS0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli H56|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>A1SAQ0|hydroxymethylbilane synthase|EC 2.5.1.61|Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)|TrEMBL
MLALAQLTQTIRWKIGMSQNLIRIATRKSPLAMWQAEFVKAELERIHPDLTVELLPMSTK
GDVILDTPLAKVGGKGLFVKELEVAMLEGRADIAVHSMKDVPVDFPEGLGLEVICEREDP
RDAFVSNTYKSIDELPQGAVVGTSSLRRQCQLRARRPDLIIKDLRGNVGTRLAKLDSGEY
DAIILAAAGLIRLKLAERIAGFISTEESLPANGQGAVGIECRTNDERVKALLAPLEHKET
RLRVLAERAMNTRLEGGCQVPIGAFAEIEADTLTLRGLVGNPDGSEVITGSVTGSTADAI
ALGHQLADDLLSRGAKTILDAVYARN
>I0NTH9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Heidelberg str. 41565|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>E4U4X8|hydroxymethylbilane synthase|EC 2.5.1.61|Oceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 / 506)|TrEMBL
MRVIVVGTRGSLLALTQTRWAVERLKENWPETEFKIKTIQTKGDRGADPREQNIFVGELE
EALRRGEIDIAVHSLKDLPTTQPEGLVIAGVPRRVDPRDVFIGRNSVARMADLPKGARIG
TSSVRRRAQLLAWRDDLEIVPLRGNVDSRLKRLVSEDLDGIILAAAGLLRLEMRNRIGEF
VDPEILLPAPGQGALALEVREGDDMADELAYSLNHAPTRARVLAERGFLHGLGAGCLAPV
GALAQIEDDVLVLDAGVLSLDGKTLIRGEIEGDPEEAWELGLELARDVLEAGGREVLAEA
AGN
>I2IYL3|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus parainfluenzae HK262|TrEMBL
MAVLKTLKIATRQSPLALWQANFVKDQLEKFHPTLSVELVPMVTKGDVILDSPLAKIGGK
GLFVKELENALLEKRADIAVHSMKDVPMEFPEGLGLSVICKREDPRDAFVSNTYRSLDDL
SQGAIVGTSSLRRQCQLKQLRPDLDIRSLRGNVGTRLSKLDNGEYDAIILASAGLIRLGL
AERIASFIEVEQSLPAAGQGAVGIECRVDDEEVKALLAPLSDATTTTCVLAERAMNTRLQ
GGCQVPIGGYAIEQNGEIFLRALVGETDGSAIIRAEGKSAVENAEALGVSIAEQLLAQGA
DKILAKIYSA
>G0L528|hydroxymethylbilane synthase|EC 2.5.1.61|Zobellia galactanivorans (strain DSM 12802 / CIP 106680 / NCIMB 13871 / Dsij)|TrEMBL
MSKVIRIGTRDSELALWQANTVKNKLEALGHKTTLVPVKSTGDLVLDKPLYELGITGIFT
KTLDVAMLNGDIDIAVHSMKDVPTALPKGIVQAAVLERANFLDILAFKKNEEFMGERDAI
IATGSLRRKAQWLNRYPTHTVVDLRGNINSRYEKLENNDWNGAIFAAAGLERIGLEPENT
IGLTWMVPAPAQGAIMVVAKEDDEFIREACAEINHEPTEICTKLEREFLRILEGGCSAPI
GALATISKENEVTLKGVLLTVDGKKKLEAEFTAPLGKHSYLAKDCANSILSRGGKLLMTY
ATDIVENTKIFSTRTLTPDQINLFDQDIKVKSEDFIKISPNRISSLILKKEIQNVIITSQ
NTVEAILKSVSPEELKFKNIYCVGGKTKRMIKRYIGPVKHQEKDAKNLANYLVEYMEGTE
VTYFCSNLRLDHLPTVLAENNIKVREIEAYTTKHAPAEVEDSVEGIMFYSPSTITSYLLK
NSPDNRVAYCIGDTTAEEARKHFETVYVAKIPTVESVIELVNQTYGKD
>D8KKE7|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium pseudotuberculosis (strain FRC41)|TrEMBL
MTFTIGTRGSLLATTQSGHVRDALISQGYSAELSIVTTPGDVNMAPVERIGVGVFTQALR
DVLVKGGCDIAVHSFKDLPTQRDPRFHLIVPERADARDCLVARDGLTLAELPQGARIGTG
APRRISQIKALRPDVECVPLRGNIDTRMGKVFSGELDAVVLAYAGLSRVGRGDEATEVFN
PERFLPAPAQGALAIECRVDDAAAVAAINAIRNAEDETCALAERVVLNRLEAGCTAPVAA
HSVIIEQELQVTGAVISLDGSKVLRATMTGGLSEAVAIGEKVAAKLIQDGAAELLS
>H7WMN4|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli H9|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>Q9AKR9|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacter capsulatus|TrEMBL
MEQMPSPNAPLKIGTRGSPLALAQAFETRSRLMAAFDLPEEAFEIVVIKTSGDNAALIAA
DKPLKEVGGKGLFTKEIEEAMLAGSIDIAVHSMKDMPTLQPEGLILDCYLPREDTRDAFV
SMKYNSLAELPEGAVVGTSSLRRRAQLAARRPDLKMVEFRGNVQTRMKKLGEGVADATFL
ALAGLNRLGMSEVAKSAIEPEDMLPAVAQGCIGIERREADTRAKMLLDAIHHAPSGLRLA
CERSFLLTLDGSCETPIGGLSVLEGDQIWLRGEILRPDGSETITGEIRGPAADGVALGAE
LAKQLLAKAPADFFCWR
>C6V4N6|hydroxymethylbilane synthase|EC 2.5.1.61|Neorickettsia risticii (strain Illinois)|TrEMBL
MLSLKVGARCSTLALAQARLVERALAPYCERIDLVGVRTSGDILSDIPLTEVGGKALFLK
ELEEKLLTGEIDIAVHSMKDVPAFYHDDLEVVPVLKRAIPNDVFVSFRYPNMLSLPSGAV
IGTCAPRRVVQLNQRFRVIPLRGNIATRVEKAKNLDGIILAFCGLERLGLCKMISEVIHE
DVMLPGVAQGALCVEFRKKDHFLRELILNISDRETIICTTAERAFLEEINGDCKTALGAL
AVVKNNTLYFTGMLGKDNRPCYFRTSGSCLNAKQIGRSAALALLRM
>I4X1P4|hydroxymethylbilane synthase|EC 2.5.1.61|Planococcus antarcticus DSM 14505|TrEMBL
MRKIVVGSRRSKLALTQTNQFIDKLKAAGAPFEFEIKEIVTKGDRIVDVMLSKVGGKGLF
VKEIEQALFDREIDFAVHSMKDMPSVLPEGLAIGCIPDREDPRDAYIANDHVKLMELPVG
AVVGTSSLRRSSQLLLIRPDLDIQWIRGNIDTRLAKLKAGDFDAIILAAAGLKRMGWKDD
LVTEFMEVDDCLPAIGQGALGIECREDDKELIAELAKLDHENTALAVNAERKFLKDMDGS
CQVPIAGYATVNNGEITFTGLISSPEADQVFKEVSISRDPIEAGRIVAEKISAQGGYDLI
QRVKAESDV
>H4GCH0|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-189|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>G4NYN5|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus subtilis subsp. spizizenii TU-B-10|TrEMBL
MRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGLF
VKEIEQALLNEDIDMAVHSMKDMPAVLPEGLVIGCIPEREDPRDALISKNRVKLSEMKEG
AVIGTSSLRRSAQLLIERPDITIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKQD
IVTEFLEPERCLPAVGQGALAIECRESDEELLALFSQFTDEYTKRTVLAERAYLNAMEGG
CQVPIAGYSVLNEQDEIELTGLVASPDGKIIFKETVTGNDPEEVGKRCAALMTDKGAKEL
IDRVKRELDEDGK
>C0GG56|hydroxymethylbilane synthase|EC 2.5.1.61|Dethiobacter alkaliphilus AHT 1|TrEMBL
MKKTIVVGSRDSELALTQTHFVIGELQKHFPDVDFTVKHIKTEGDKILDVALSKIGDKGL
FVKEIENALLSKEIDFAVHSMKDVPTAVPDGLQITTITEREDPRDCYIAKDGKTRLFDTP
QGAVIGTSSLRRSAQLLHQRSDFEIVPIRGNLNTRFRKLSEQDMHGIILAYAGVYRLGWA
DKITEIIDFEKSLPAVGQGALGIETRSDDDFTINIVSALNHDTTASAILAERAFLRQLEG
GCQVPIGAYGRLEAEELVLDGVVAGLDGSTVLRDQVRGSADESDALGKKLAQKMVERGAD
EILKQVRQEFDANA
>G2D6D5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TX1999|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>G4KNB4|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia japonica (strain ATCC VR-1363 / YH)|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQITQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGIIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDADPRHLSKLAYREAFAGNTEALATATHKSNSTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>H7UNW3|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 67-8|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>C5ABI3|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia glumae (strain BGR1)|TrEMBL
MNSETLTADVPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELETALADGRADLAVHSLKDVPMSLPEGFALTAVMRREDPRDAFVSND
YASLDELPTGSIVGTSSLRREAMLRARYLDIDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLDARIRSLIEVEASPPAAGQGALGIEIAAARAELARWLAPLHDPATALACEAER
MVSRALGGSCEVPLAAHAVWDGDVLQLTGRVSNPSGTRVLNARARAAVSTPDAALALGRQ
VADELARQGAFEIVEALLGGRS
>F0A1L6|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis OX99.30304|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVILQADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>B3J5V8|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus anthracis Tsiankovskii-I|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>F3GJ65|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. pisi str. 1704B|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFASLDQLP
AGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSAISVDDSLPAGGPGGA
>B3YUN0|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus W|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAYINDAVTERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSILLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>D3V6J3|hydroxymethylbilane synthase|EC 2.5.1.61|Xenorhabdus bovienii (strain SS-2004)|TrEMBL
MKIIRIATRQSPLAMWQAQYVQKQLEQFHPELKVELIPMVTRGDVILDTPLAKVGGKGLF
VKELELALLENRADIAVHSMKDVPVEFPDGLGLVTICERGDPRDAFVSVKYTSLDELPIG
SIVGTSSLRRQCQLRQLRPDLVVRDLRGNVGTRLGKLDNGDYDAIILAAAGLKRLGLEDR
IRMPLEPELLLPAVGQGAVGIECRLDDKQTRELLAPLNHTGTEICVLAERAMNTHLEGGC
QVPIGSYAIWQGNNIWLRALVGAPDGSITVRGEKTVSPEEARRAGVELAEELLEKGARQI
LADVYQRNPPE
>F5P1K4|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri K-227|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>E6NNA3|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain F32)|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSMKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCHLERAFIKGLNGGCQ
IPIGVHASLMGDRVKIRAVLGLPNGKEVITKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKAQLF
>D8N8X2|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia solanacearum|TrEMBL
MSSNARPTSVESPLAAQAPTKLVIASRESRLAMWQAEYVRAALQKYYPACDVSILGMTTR
GDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMELPPGFALSAILEREDP
RDAFVSNDYADLAALPAGAVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLSKLDRGDY
AAIILAAAGLKRLGLSARIRAVIAPETSLPAAGQGALGIESRVDRHDVQAWLAPLHHVPT
TLAVTAERAVSRQLGGSCQVPLAAFAQWTDAGALRLRAFVASPDGSRKLAAEAEATPATP
AEAEALGARVAQQMLDGGAHDILATLGADAPPAT
>E1Q9K3|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain Cuz20)|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIRAVLGLPNGKEVIAKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKAQLF
>D3PRS7|hydroxymethylbilane synthase|EC 2.5.1.61|Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21)|TrEMBL
MGRVRIATRGSRLALWQAGWVQQQLERLGAQVELVVVETQGDRESRPFAQMQGQGFFTKA
VQDAVLNWEADLAVHSFKDLPSARPEGLEIAAVPKREDPRELLLVRPEALDEAAPGLPLR
SGALAGTSAARRQAQLRQLRPDLGLKELRGNVPTRVDKLRCGEYDAILLAYAGLKRLELD
LSGLYTQVLPTTVLVPAPAQGALALECRSDDHRLKALLQPLDDPQARRTVEAERGLMQKL
AGGCQLALGALAQAGPQGLMLLAWYGGRRYQAQAPTPEAVAQVVFDQIRAEHPEVVCESP
>D0FMZ1|hydroxymethylbilane synthase|EC 2.5.1.61|Erwinia pyrifoliae (strain Ep1/96)|TrEMBL
MSDKILRIATRKSPLALWQAKYVQQRLIDCHPGLRVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEQAMLSGSADIAVHSMKDVPVAFPQGLGLVAICERDDPHDAFVSNRHASVDSLP
QGAIVGTSSLRRQCQLSARRPDLVIHSLRGNVGTRLGKLDAGEYDAIILAVAGLKRLGLS
DRIRQVMPAEESLPAVGQGAVGIECRLEDMHTIGLLAALNHDETACRVSAERAMNTRLEG
GCQVPIGSYALLEGDQLWLRGLVGSPDGSQMVRGERRGSRADAEKMGISLAEELLDNGAR
DILAAVYQGNPPA
>D5STI7|hydroxymethylbilane synthase|EC 2.5.1.61|Planctomyces limnophilus (strain ATCC 43296 / DSM 3776 / IFAM 1008 / 290)|TrEMBL
MPVLRIATRASQLALWQANFVADSLRSLDPELTVELVHVTTTGDRVQGEPLRQFGGQGVF
TREVQAALLEGRADIAVHSLKDLPTVPTAGLELAAVPARAPVADALLLPTGHSGPASLAM
LPRGARIGTGSPRRQAQLLRIRPDLVCSEVRGNLDTRIRKLDAGEYEGLILAVAGLSRLG
WSDRISLILAPPTMFPAAGQGALGLECRHGDEATIRWVSQLEDRQTRLAVDAERAVLRTL
EAGCHAPVGTWASWKSPETLHLEAILIAPDGSETLAAASSMQGPLSQYGSGNALDAAHEL
GANVAHLLLKQGASRYLV
>D0Z0U6|hydroxymethylbilane synthase|EC 2.5.1.61|Photobacterium damselae subsp. damselae CIP 102761|TrEMBL
MWQAEFVKAELEKAHPGLVVELVPMVTKGDVILDTPLAKVGGKGLFVKELEVAMLEGRAD
IAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNRYNSLEELPQGSIVGTSSLRRQCQL
RSQRPDLIVKDLRGNVNTRLRKLDDGEYDAIILACAGLKRLKMDDRIRAAIAPETSLPAV
GQGAVGIECRLDDTRVRDLLAALNHQETATRVLCERAMNNRLQGGCQVPIGSYAELQGDQ
IWLRALVGEPDGSQIVRGEISGSANDAEALGTQLAEQLLADGAKPILERLYQEH
>E5ZG39|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 305|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>E5THW2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus CGS01|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>F0NI03|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfolobus islandicus (strain REY15A)|TrEMBL
MKIRIAARGSKLSRIQVDMLGEKLKKIGIEYEIINIKTKADLFSTEPLSKLGKGVFEKEV
NEAVLEGKADIAVHSMKDILSEINPSLEIFAVLERDPPYDILIAEKNLDKLDSNITIGTS
SIRRKNFLKYIKPEINTKDIRGNVDTRIRKYLSKEYQGLILAEASLKRLNMTMNYHRLNV
YDFTPEANQGIIVALGRKKDEKIKEIFKEINHKDTLDEALAERAVISLVGGGCHSPIGVL
FKKEGKEFYGIASYSDGKKKITVSISKPGDPYTIGSELGLLLKKEMKNEDIIP
>A3EML6|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae V51|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVDDQRVRALLTPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDHIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>F4DIF8|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydophila pecorum (strain ATCC VR-628 / E58)|TrEMBL
MPSTSCSKFFEDLREGRLPLKIASRDSNLAKAQVNECLQLLRTSYPKLQSLLITTKTQGD
RDKLTPLHTIENSDFFTRDVDALVCQGSCHIAIHSAKDLPTPSPLPLVALTRCLHPADLL
VYADHYTKEPFPSNPRLGSSSMRRGEVLKQLFPLGQILNIRGTIEERLQQLHNNTYDAVV
LAKAAALRLGLSFLYSELLPPPYHPLQGRLALTAYESIDLWRTFLSPIHDTNLRYSI
>F2LWE6|hydroxymethylbilane synthase|EC 2.5.1.61|Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2)|TrEMBL
MLLLRKQLKIGTRGSKLALWQAEFAKKRLEDKGFECEIVPIKTSGDKTDKPLYQLGGKGL
FIKEIEKALLDKTIDIAVHSLKDMSVFEDERFDFIVFERDYWEDIFVSFEGNFLEIKKNA
RVGTSSLRRRAELLQYRDDFEFVDLRGNLDTRLKKLRDGEVDAIVVSKSGLKRLGLYDEA
YMYDLRFATPAAGQGVIAVEFLSDFEFRDELKQLEDEKTRICIDSERAFVRQFNASCNYP
IGALARFEQDEFFMQITYGFVDNLRRVIKYSRRDISPLFVFSDVVEYVKKKVKDYENRG
>F3HE34|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. maculicola str. ES4326|TrEMBL
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLIVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLENNADIAVHSMKDVPMDFPPGLGLFCICEREDPRDAFVSNTFDSLETLP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITSSISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNG
GCQVPIACYAVLEGDNVWLRGLVGDPSGSLLLHAEARAPQTAAQALGVEVAEALLAQGAA
DILKAVYGEANNP
>F8ZDF0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae HC-49A2|TrEMBL
MTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKG
LFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLP
SGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELE
SRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQG
GCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAK
EILERLYCDHE
>D0RNS6|hydroxymethylbilane synthase|EC 2.5.1.61|alpha proteobacterium HIMB114|TrEMBL
MSLSLIIGSRASFLAKIQTFIVKQELKKKIKNIKITTKYHSTKGDKNQGHMPWKNLGYGI
FTTSLTNELINKNFNCVVHSYKDLPVLKSKTDYYVITRDDPRDVLLVKKKCLNKKKFIVG
TSSPRRKSSVKDLKDLTGIKDIKTKTIRGNVTTRLLKVISKNQYDAVFMAKAAIDRIFKY
GNKVDKVETKKFLNLFKKFKPFILPLSIFPTAASQGAIAVEYLKNDKKTKSTLNKINCKK
TLSICNQERSLLKKYGGGCGLDIGITIEEIKNNNFLFSKGVDARNKKEFHINKILNKRSI
KKTKSIFPQNIKDYQMFSRIELKLPKIKNSTVILTRPDFSIKELNNNNFFITSGIQTWKR
AAKENKIPQCSFDGLGEDYRLPEIYYRNYKNIKKITYKKSMSIYKTKQINGYELIPQINS
KTINNLFNAKVFYWMSYSAFKLAKAIKPDITKYQHCSGPGSTFEQLKKEIPKKRLKLFFN
YKDFKESVYQAR
>I0MEV4|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Heidelberg str. 41573|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>G4MDP4|hydroxymethylbilane synthase|EC 2.5.1.61|Candidatus Burkholderia kirkii UZHbot1|TrEMBL
MVNGRASNRRQHAAAFCASRSVQRAKGGCPPPFTSIQTHRGRPGRRIGQGSLALPVCKWT
LACVLPLFADIYLSIHPSFDRASMNSETHSTTPPASLTIASRESRLAMLQAEHMRCALHK
LYPSCDVKILGMTTRGDQILDRTLSKVGGKGLFVKELEAALADGRADLAVHSLKDVPMEL
PEGFALGAILEREDPCDAFVSPHYESLEALPAGSIVGTSSLRREAMIRARFAHLDVRPLR
GNLDTRLGKLDRGEYAAIILAAAGLKRLGLETRIRAWLAPSESLPAAGQGALGIEIRADD
ADLAAWLKPLHDEKTALAVEAERAVSRALGGSCEVPLAAYAEWHDDSLHLRGAVSMPDGK
RVLRAEETVRSPDVTGALALGKRVSADLEAQGAMDVVKALTTMSRAGGPNSAPAGPKS
>F0B0F9|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis 961-5945|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>F3KX68|hydroxymethylbilane synthase|EC 2.5.1.61|Hylemonella gracilis ATCC 19624|TrEMBL
MSMNLTIATRESRLALWQAEHVQGLLRQQGHAVTLLGMTTQGDQILDRALSKVGGKGLFV
KELEVALDEGRADLAVHSLKDVPMELPEGFVLAAVLEREDERDAWVSPHCAGLADLPSGA
IVGTSSLRRVVLLREALRALGRDDVRIEPLRGNLDTRLRKLDEGQYHAIVLAAAGLKRLG
LAARIRKIFTPEEMLPAAGQGALGIEIKHGATAQTAALEQALSNLAHQPTWLRVAAERAV
SRAMGGSCSMPLAAHAAFVSSPAPKGATLRLRAAWGDVQGRLPLVQAQDEAAVHGLDDAE
ALGLRVARQLQEAVRRAGGTLQS
>F0L3H0|hydroxymethylbilane synthase|EC 2.5.1.61|Agrobacterium sp. (strain H13-3)|TrEMBL
MQTKPFRIGTRGSPLALAQAYETRNRLMSAHGLPEDMFEIVVLSTKGDRITDRALSEIGG
KGLFTEELESQLLSGELDIAVHSSKDMPTVLPKGLYLSAFLPREDMRDAFIGRTAPKLLE
LPQGAVVGSASLRRQALIRRLRPDLSVIIFRGQVETRLRKLEEGQADATLLAFAGLKRLG
MENVPTDILDPKDFPPAPAQGAICVESRIGDTRMDELLSPINDIPTYDAVTCERAFLAAL
DGSCRTPIAGFATCHGEELHFSGLILTPDGQTSHSVEISGARKDAEDLGRKAGEDVRARA
GSNFFDGWS
>H7R5Q3|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli Z163|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>H3XWH0|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-88|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>H7YCI5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 55037|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>Q1ZLA8|hydroxymethylbilane synthase|EC 2.5.1.61|Photobacterium angustum (strain S14 / CCUG 15956)|TrEMBL
MSNQPIRIATRKSPLAMWQAEFVKAELEQAHPGIIVELVPMITKGDIILDTPLAKVGGKG
LFVKELEVAMLEGRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNKYNNIDELP
QGAIVGTSSLRRQCQLRAQRPDLIVNDLRGNVNTRLRKMDEGQYDAIILACAGLKRLKME
DRIRSEIAPEVSLPAVGQGAVGIECRLDDTRVRQLLAALSDQATTTRVLCERAMNNYLQG
GCQVPIGSYAELEGDQIWLRALVGEPDGSKIVRAEIRGPIEQAEQLGETLAEQLLNDGAR
DILDRLYGNA
>F9DVL7|hydroxymethylbilane synthase|EC 2.5.1.61|Sporosarcina newyorkensis 2681|TrEMBL
MRKIIVGSRRSNLALTQTKWFIEQMKQAGAPFEFEIKEIVTKGDQILDVMLSKVGGKGLF
VKEIQQALFDKEIDFAVHSMKDMPAVIPDGLTVGCIPERVDPRDAYIANDHVRFMDLPIG
AIVGTSSLRRSSQLLMLRPDLEIKWIRGNIDTRIRKLRDGEYDAIILAAAGMKRMGWDDS
TVTEYLALDDCIPAVGQGALAIECRQDDTELLDELAKLTDQKTWIELQAERTFLNEMDGS
CQVPIAGFAKYDGNEVELTGFIASPDAIEVFRETVKGTDPVSVGKEVSKILREQGAAEVI
EKVKADMDA
>I0K296|hydroxymethylbilane synthase|EC 2.5.1.61|Fibrella aestuarina BUZ 2|TrEMBL
MWETVWQKLRTTVEIVAAERLQRCSQSIVAHHASANGLYLCTMHIRIGTRSSRLALWQAE
YIQELLQAGGLTSELVLIETKGDQILDRSLSKIGSKGVFTQELEDQLRAGQIDIAVHSAK
DLQSSLPADLSLIAFTERERVNDVLVSRDTTLSLTSGQAFVVGTSSTRRVAMLKHYCPHI
KVVDMRGNLQTRLRKLDEGQCDALLLAYAGVHRMHYDDLIAEHLPTDDFTPAVGQGSVAI
EVADTLPLDKLAAVRRLTNHEPTEVCVKAERAYLRRLEGGCSIPVFALATHTTEGQVSLT
GGIISLDGNEWLRETFVGPPAEAEKLGHDLAEAVLTRGGDAMLQGIRAAL
>E4T7M2|hydroxymethylbilane synthase|EC 2.5.1.61|Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4)|TrEMBL
MSKKFVVATRPSLLAYTQTQQTVDLLRVKNPDCEFEIVKISTHGDTVTDKPLTAFGGTGV
FVKELENALYEGKAHFAIHSLKDVPSIQPEGLVLAAFPTRQDPRDLLLTRGGVSVADLPS
PCVIGTGSPRRMVQVAKLKEQITFADLRGNIDTRLKKLEDGQYDAIVLAAAGLKRLGKEI
AESAYMPTDVCLPAIGQGAIAIECRADDAETIAMLKSINDAATETAIVAERSYMKTIGGG
CKFPLGAYATVESDEVNLHVMLGNHHTGQIIRMHETSTVADAEKLGQKLGEAIIAEAEKQ
GIEILR
>C1DTV2|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825)|TrEMBL
MKVRIGTRKSQLALWQANYIANLINQIHGVEVELVKITTSGDKILDVPLAKIGGKGLFVK
EIEDAMLKGEIDIAVHSLKDVPTQLPEGLDIIAITEREDPRDAFLSTKYKSLKDLPAGAV
VGTSSLRRKSQIMKMRDDLIINDLRGNVDTRIRKLEEGQYDAIILAYAGLKRLGLDSKAS
YIFSPQEMIPAVCQGFLGIEARVDDERIKKILEPINNQESFIRATAERSFLKTLEGGCQV
PLGAYCEIKDDFIHITGFIADLEGKTFIKESLSEKLTNINQAKELGQRLANILLKRGGKD
ILTKIYNL
>G6X9G1|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium abscessus 47J26|TrEMBL
MIRIGTRGSLLATTQAGGIRDALRAKGHEAELVIVTTAGDQSAAPVEQIGVGVFTAALRE
AIADDVVDVAVHSYKDLPTAADPRFVIPAIPPREDYRDALVARDGLVLGELPAGSVIGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLSRVSNGDLDGVVVARAGLARIGRLDHITETLE
PVQVLPAPAQGALAVECRSEATDLVAVLAELDHADTRAAVTAERALLAELEAGCTAPVGA
IAEVVESIDEEGRVFDELSLRGCAAALDGSDVIRASGIGTPDRAAELGLAVARELLDLGA
RALIGR
>G6X9G1|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium abscessus 47J26|TrEMBL
MIRIGTRGSLLATTQAGGIRDALRAKGHEAELVIVTTAGDQSAAPVEQIGVGVFTAALRE
AIADDVVDVAVHSYKDLPTAADPRFVIPAIPPREDYRDALVARDGLVLGELPAGSVIGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLSRVSNGDLDGVVVARAGLARIGRLDHITETLE
PVQVLPAPAQGALAVECRSEATDLVAVLAELDHADTRAAVTAERALLAELEAGCTAPVGA
IAEVVESIDEEGRVFDELSLRGCAAALDGSDVIRASGIGTPDRAAELGLAVARELLDLGA
RALIGR
>E6NQB4|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain F57)|TrEMBL
MKKLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDAPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLERAFVKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKALDLVQELLEAFLQSGAKEIL
EKAQLF
>F4LGL6|hydroxymethylbilane synthase|EC 2.5.1.61|Bordetella pertussis (strain CS)|TrEMBL
MAAVERLTIATRASRLALWQAEHVRDLLRARYPACSVELLTLTTRGDQILDRTLSKVGGK
GLFVKELETALLDGRADLAVHSLKDVPVDLHAPFELSCVLERADPRDAFVSNDYGSLADL
PPGAAVGTSSLRRESQIRARYPHLVVKPLRGNLDTRLGKLDNGDYAAIVLAAAGLERLGL
AARIRALLEPDDSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAERAVSRMLG
GSCQVPLAAYARIDGDELALRALVAAPDGRRIVRAERRGPRDQAQAIGESAARDLLADGA
DAILAELLPTSPAP
>B9WCU8|hydroxymethylbilane synthase|EC 2.5.1.61|Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841)|TrEMBL
MPHHIMSINDSNHVQIGGRKSKLAVVQSEIVKKAIEDTFPNLSCSILALSTLGDKVQTQP
LYTFGGKSLWTKELEILLLDSVDEFPQLDLIVHSLKDMPTNLPEEFELGCIFQREDPRDA
IVMKQGSSYKSLKDLPAGAIVGTSSIRRSSQLIKNYPHLRFESVRGNIQTRLNKLDQPNN
EYCCLILASAGLIRLGLGHRITSYLDDMYYAVGQGALGIEIRKGDDNIKSILKKIEDPIA
TICCLAERSLMRYLEGGCSVPLGVHSDYNESKQELTLKGIIVSPDGTVSIEDQVIKRITC
DEDCEQVGIELGDKLKAKGAKEILDKIDMTRNINARPTEV
>B3HAU0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli B7A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHKTALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>C2KT65|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus mulieris ATCC 35243|TrEMBL
MHMIGSAQRPLVIGTRGSKLALTQTRMVAADLEQRGLAVRIETFVTEGDTNRASLSSLGG
VGVFAAALRVALLEGRCDLVVHSLKDLPTVEVPGLVVAAIPARVDPADVLVARDGLRLAD
LPAAARVGTGSPRRARQLAAARPDLSLVDIRGNVPTRIGRVRGLGTRAEQIGLDQGRAKE
DLDAVVLARAGLRRLGVEDVATDDLSETILPAGGQGALALETVADGLAAEEGRILAQTLR
IVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGQLTWENNATELLAGVLELRARVVGDNG
ESVEVSGETTVLLGTDADQRDFALAAAEQLGVDLATELLANGAGEMANLQAAKESGTTQF
>C2KT65|hydroxymethylbilane synthase|EC 2.5.1.61|Mobiluncus mulieris ATCC 35243|TrEMBL
MHMIGSAQRPLVIGTRGSKLALTQTRMVAADLEQRGLAVRIETFVTEGDTNRASLSSLGG
VGVFAAALRVALLEGRCDLVVHSLKDLPTVEVPGLVVAAIPARVDPADVLVARDGLRLAD
LPAAARVGTGSPRRARQLAAARPDLSLVDIRGNVPTRIGRVRGLGTRAEQIGLDQGRAKE
DLDAVVLARAGLRRLGVEDVATDDLSETILPAGGQGALALETVADGLAAEEGRILAQTLR
IVDDEPTRLEVSAERALLRYLEAGCAAPLGVRGQLTWENNATELLAGVLELRARVVGDNG
ESVEVSGETTVLLGTDADQRDFALAAAEQLGVDLATELLANGAGEMANLQAAKESGTTQF
>H3TUW6|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21342|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>C8X0N3|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfohalobium retbaense (strain DSM 5692)|TrEMBL
MRSLTIATRGSKLALWQANHIKGRLEERYPGIEVHLEVIKTQGDKILDVPLAKIGGKALF
VKEIEEAMLDGRADLAVHSMKDVPAELPEGLTLGVIPQREDYTDCLLSQHYTTLEEIPEG
ATIGTSSLRRKTQLLRLRPDLVIQDLRGNLDTRIRKLEEGMFDAIVVASAGLRRLQTGAR
YMTELAPPQFLPAVGQGALGIEYPEDRKDLEEMLGFLDHPPTRFCVLTERAFLHRLEGGC
QVPIGGHAVMSESNKLHLDCFVADLHGQQCLRREGEAKPKDGVALGQRLADDILASGGAE
ILREIYACDDE
>A6AVU0|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio harveyi HY01|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYNNIDEL
PQGAVVGTCSLRRQCQLKEYRPDLVIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLEL
EERIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHQDTADRVRCERAMNLTLE
GGCQVPIGSYSLLDGDNIWLRALVGEPDGSLIVRGEIRGHRNDAEALGVQLANELLENGA
RDILTKLYADHE
>D8F8I8|hydroxymethylbilane synthase|EC 2.5.1.61|delta proteobacterium NaphS2|TrEMBL
MNIRIGTRGSKLALTQSEWIKEQLEIRHSGIHVDLIKIKTTGDKILDTPLSKIGGKGLFV
KEIEEALLQNRIDVAVHSMKDVPAELPEALMLSTFPPREDPSDALIAQENRRLDQLPEGA
RVGTSSLRRGAQLLHLRPDLTLVPLRGNVDTRLGKLKSGEVEAVILATAGLNRLGLSGVI
TQRIPFHQLLPAVGQGALGLEVRRDDRETIRRLDFLNHDDTRTAVTAERGFLKTLEGGCQ
VPIAGFAQIVGDNLSFEGLVAELDGSRIYKEIATGSRDDAEKIGIEAAKTLLSSGAGDVL
RRLYKAADPGTKNEGA
>C9XS10|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium difficile (strain CD196)|TrEMBL
MNIVVGTRGSTLALIQTEWVINELKKKYPEISFEIKIIKTKGDLIQNVSLDKIGDKGLFV
KEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPRDVLILREGYKNLDDLPHG
AVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDENMHGIVLAASGIIRANLQDK
ISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLKDENTEIQILAERGFLDGVNGSC
HIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDGDISSPRELGLKLAKLVLKEYENYE
G
>G6YNJ4|hydroxymethylbilane synthase|EC 2.5.1.61|Marinobacter manganoxydans MnI7-9|TrEMBL
MTPKGGSRGTFLPPQGNLGGHFFEPTVSVMSKRTLRIATRSSALALWQAEFIKAELERLH
DNITVELVKIKTQGDKILDVPLAKIGGKGLFVKELEEAMLDGRADLAVHSMKDVPMEFPE
GLGLVAICEREDPTDAFVSNHYDNVDALPHGAVVGTASLRREAQLRAYRPDLEIRVLRGN
VNTRLAKLDAGEYEAIVLASSGLKRLGFHDRIRYCLPDTISLPAVGQGALGIECRVDDHD
LLAMLEPLDHKDSSDRVKAERALNRRLEGGCQVPIAAYALLEDDDTLWLRGLVGAVDGTE
VFRVEGRAPRAEGERLGRELAEDLLALGADRVLAEIYGHTPT
>H6PHX4|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia rickettsii str. Brazil|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>A9KP83|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg)|TrEMBL
MRIIRIGSRESELAVRQSRILIDSIKQYHNEIETELITMKTTGDIILDKSLDKIGGKGLF
VKELDLALIEGRSDLSVHSLKDMPMETPEELPILAFSKREDPRDALVLPLGCTEIDPVLP
IGCSSQRRMLQLKKIYPGANYKGIRGNVLTRLEKLDRGEYGALVLAAAGLKRLGLESRIS
RIFTTEEIIPAAGQGILAVQGRAGESYEFLKQFHNEEATFQAVCERAFVKTLNGGCSSPV
AAYAKVEDEMITVTGLYFDEITGDYITGNLTGKKEDAEQLGEMLANKLRTEWCMR
>H7SA17|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 84-2|TrEMBL
MKELVIATRKSQLALWQSEFVADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLILAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYAFSKDELIPAASQGALGIESTDDEKILEFLKCLNDDNALIETTIEREFIATLEGGC
QVPIGINAELLNDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEI
LKKAESMI
>I3BJX9|hydroxymethylbilane synthase|EC 2.5.1.61|Haemophilus parainfluenzae HK2019|TrEMBL
MAVLKTLKIATRQSPLALWQANFVKDQLEKFHPTLSVELVPMVTKGDVILDSPLAKIGGK
GLFVKELENALLEKRADIAVHSMKDVPMEFPEGLGLSVICKREDPRDAFVSNTYRSLDDL
SQGAIVGTSSLRRQCQLKQLRPDLDIRSLRGNVGTRLSKLDNGEYDAIILASAGLIRLGL
AERIASFIEVEQSLPAAGQGAVGIECRVDDEEVKALLAPLSDATTTTCVLAERAMNTRLQ
GGCQVPIGGYAIEQNGEIFLRALVGETDGSAIIRAEGKSAVENAEALGVSIAEQLLAQGA
DKILAKIYSA
>I4A0F1|hydroxymethylbilane synthase|EC 2.5.1.61|Ornithobacterium rhinotracheale DSM 15997|TrEMBL
MTTLKLGTRKSPLAMWQALQAQKRLEEFGHSVEIVPIASEGDLKLKQPIYELGITGVFTK
TLDIALVNGEIDLAVHSLKDVPTQLAQGLQLSACLPRGDHRDILVFKSSDILEKEKRTIA
TGSLRRKAFWHHRFPQDTVVDLRGNVQLRLQKLLDNDWDGAIFAYAGLNRSEILQNLTKH
NLEYQFIENMISAPSQGIVGIVTRQDLDLSEISDTQAQTAGEIERAFLRKLEGGCTAPIG
GYAHIENEKVHFSGAILSLDGTQKIEISETRPLGDAQTLGEEMAQICLDQGAGGIIQEIK
KQIGA
>Q126H6|hydroxymethylbilane synthase|EC 2.5.1.61|Polaromonas sp. (strain JS666 / ATCC BAA-500)|TrEMBL
MSAASQPGNPIAPRKIIIATRESRLALWQAEHVKALLESRLGWQVELLGMTTQGDQILDR
SLSKVGGKGLFVKELEVALSEGRADLAVHSLKDVPMDLPDGFALACVLEREDPHDAFVSN
QFASLADLPQGAVVGTSSLRRLVLLKALRPDLNIEPLRGNLDTRLRKLDEGHYHAIVLAA
AGLKRLGLQARIRGIFAPDDMLPAAGQGALGIEVRADRHDLMQALGTLAHQPTWLAVTAE
RTVSRAMGGSCSMPLAAYTEGPAAEGSEGMQLHATWGDPATADAPAGQPLAPLVRVQKTA
VVRSFAEAEALGEAVAAQLRAGGAVWASNTPSDT
>H7V415|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli LMG 9854|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>B4D5X7|hydroxymethylbilane synthase|EC 2.5.1.61|Chthoniobacter flavus Ellin428|TrEMBL
MKSIILGTRASALAVAQVELTTKALAAAFPAMQIERREFVTRGDKKLDLSLLRANEAGGK
GLFTKELEDALLNGSIDVAVHSLKDLPGHNPPGLDITAVLERAPTADVLITKQPQTLLDL
PQGVLLGTSSVRRARQLQWRRPDVRVEEWRGNVQTRLRKLAERDDVTGIILAQAGLERLG
HDLSAGRLETEHGKFYVTSLAEDLLPAIGQGAIALQSRADRAEVAAVLQKIDHRETHLAI
RAERELQRLLAGDCALPVGVRTKLLPGGIAMRAILFGPPDAPPKQAEAEAATPEAVAAEV
FAQLEQH
>F3TPC0|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU028|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>C7QKP9|hydroxymethylbilane synthase|EC 2.5.1.61|Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)|TrEMBL
MSGSPADEGSPAPGPERALRLGTRASTLALAQSGMVAEALTAATGRAVELVHVTTYGDTS
REALSVIGGTGVFVNALREAIYAGDVDFAVHSLKDLPTAAPEGLHLAAITERAAVNDALV
ARDGLKLADLPAGAKVGTGAARRMALLKMIRPDLEIVPIRGNVDTRVNHVRSGDLDAVVV
ALAGLQRLGRAEEATEVFGPDVILPSPGQGALAVECKDPELAELLAVLDSPLTRAAVVAE
RTMLAVLEAGCSAPVGGHAIALDDNVLSLTGVVATVSGSRGLRLSHAGAVSEPEALGRRV
AQALLADGAAELMEAGA
>A0L5L5|hydroxymethylbilane synthase|EC 2.5.1.61|Magnetococcus sp. (strain MC-1)|TrEMBL
MSDPQLVRIGTRGSALAVWQAEWVKSQLQAHHPGIIVELELIKTKGDKILDVPLAKVGGK
GLFVKELEEAMLDGRVDLAVHSMKDVPAEFPDGLMLGPILKREDPRDALLSIHYQSLAEL
PQGALIGSSSLRRQSQIKAKRPDLRLDWLRGNVGTRIQKLVEGQFDAIILAAAGVKRLGL
TEHVVQYLEPEEMLPAVGQGAVGIEHRVDDARIATLLAPLYHKETHSCVTAERAFLAKLE
GGCQVPIAGYATLHEDTLTLRGLVAEVEGGRVVQAQCQGPRADAYRMGQQLATQLLEAGG
GAILQAVYNQDTLS
>G4CXV5|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium avidum ATCC 25577|TrEMBL
MEDMSSIRLGTRASTLATTQSEMVAELLRSQGLDVDLATITTHGDTSTASLASMGGIGVF
ASAIRTALLEGSADIAVHSFKDLPTGRPLGLAIGAVPVREDPRDALVARDGLTLDELPQG
ASVGTGSPRRVAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGHYAEDSGKEDLDAVVLAAS
GLARLGHSDVITELLDPSVVLPAPAQGALAVECRTADVHHGKLAKALARIDDYGTRLSAT
AERAVLSHLEAGCAAPIGALAHLAPTPGMSPDVLTLDVVVAAVNGSRTIREQVSVELPKE
VEPALAAAHTLGVTAAEELLDDGAADVADLKATGSTR
>G4CXV5|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium avidum ATCC 25577|TrEMBL
MEDMSSIRLGTRASTLATTQSEMVAELLRSQGLDVDLATITTHGDTSTASLASMGGIGVF
ASAIRTALLEGSADIAVHSFKDLPTGRPLGLAIGAVPVREDPRDALVARDGLTLDELPQG
ASVGTGSPRRVAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGHYAEDSGKEDLDAVVLAAS
GLARLGHSDVITELLDPSVVLPAPAQGALAVECRTADVHHGKLAKALARIDDYGTRLSAT
AERAVLSHLEAGCAAPIGALAHLAPTPGMSPDVLTLDVVVAAVNGSRTIREQVSVELPKE
VEPALAAAHTLGVTAAEELLDDGAADVADLKATGSTR
>F8JGC5|hydroxymethylbilane synthase|EC 2.5.1.61|Hyphomicrobium sp. (strain MC1)|TrEMBL
MQATRIRIGTRGSPLALAQAHEVKDRIIAAHGLADEAVTIHVIKTTGDRVLDRPLSEIGG
KGLFTKEIEEALLTNEIDVAVHSMKDMQTVLPDGLVIGAVLPREDPRDAFISLRHESFAT
LPQNAVVGTSSLRRKAQVLHARPDLRVVDFRGNVQTRLRKLEDGVAEATFLAVAGLKRLG
MTERITSPVSMEHMLPAVAQGVIGLEIRNGDELVTPIVAALNDETTAWAVAAERAFLARL
EGSCRTPIGGHGIVAGDEVRFRGQLLSPDGKKCYDVSRTGNVKDAHDLGLSAADEILNQA
DAALLVRPNV
>H3UCM8|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus epidermidis VCU041|TrEMBL
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLF
VKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEG
SIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDN
IVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDI
IKKLNEAE
>A7GXQ1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter curvus (strain 525.92)|TrEMBL
MSNTKMNLKMMKKLETEELLTVVSKSITQLWKAREILYERKPDLKQNFKKEFDADPKKYE
ELSKISQTAQKLERGGKLKEAVKKYEELLKRSNFRHFALVAQAGAL
>D3MSR3|hydroxymethylbilane synthase|EC 2.5.1.61|Peptostreptococcus anaerobius 653-L|TrEMBL
MKLIVGTRGSKLAVTQTKIVVDAIKSNFENIDVDIKIISTKGDRILDKSLDKIGDKGIFT
QEIERQLIEGEIDFAIHSLKDMPSELGEGLVLTKTIQREDPRDLLILNSKFKKIDDPIKW
LKENDGMRIGTGSKRRSAQLLNINPNLKIDLIRGNIDTRLEKMEKESYDAIVLAAAGVNR
LKMDWINSYVLDEGSMIPAVGQGALAIEIKEGNQELVNIFEAISDDIANVCVEAERTYLA
TINGGCHMPVGALAQVNEGKLCLKGIYGSEDCKLIISSSLEGPLEDAQRIGRELADKILR
EFEEKKR
>E2K814|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC4045|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>D4S8E9|hydroxymethylbilane synthase|EC 2.5.1.61|Selenomonas noxia ATCC 43541|TrEMBL
MTTKGDRILDAPLAKIGGKGLFTKELEQAMLAGQIDIAVHSLKDMPTEIPKGLIIGAITK
RLDPGDAFVSVNYTSIEELPIGAKVGTSSLRRRAQLLAVRPDLQLLDLRGNVNTRLAKLD
AGDFDAIILAAAGLKRLGLGNRIRSILSQRMMLPAVGQGTLAIECRADDTRILSVIDFLH
DRNMSAAAMAERAFLCRVEGGCQIPVGVYADLKEDGLLHVDAMIASVDGMRVCRSRCTGS
AERAEELGISLAEELLDAGGREILKEIGIAV
>H7UII0|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli 202/04|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>D0I362|hydroxymethylbilane synthase|EC 2.5.1.61|Grimontia hollisae CIP 101886|TrEMBL
MTSTPIRIATRQSPLALWQAEFVKAALEATHPGLTVELVPMVTKGDIILDTPLAKVGGKG
LFVKELEQAMLDGRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNHYTSISELP
QGAIVGTSSLRRQCQLRAMRPDLVIKDLRGNVGTRLGKLDNGEYDAIILASAGLKRLNLH
DRIRNEIEPEEILPAVGQGAVGIECRLDDERVRALLEPLADANTTYRVLCERAMNNRLMG
GCQVPIGSYAEIHGDQIHLRALVGEPDGSKIVRGEVTGPLEKAEELGTGLAEQLLDDGAR
AILEKLYQDDV
>G8F9I5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni NW|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>C2LKN2|hydroxymethylbilane synthase|EC 2.5.1.61|Proteus mirabilis ATCC 29906|TrEMBL
MPKSTIRIATRQSPLAMWQALYVKEQLQIAHPSLVVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELALLSSRADIAVHSMKDVPIDFPEGLGLVTICEREDPRDAFVSNHYDSLEQLP
AGSVVGTSSLRRQCQLKALRPDLIIRDLRGNVGTRLSKLDNGDYDAIILAVAGLKRLKLT
ERIRSSLSAEQSLPAVGQGAVGIECRLDDHDTQALLAALNHADTATCVKAERAMNTRLEG
GCQVPIGSYAIWQNDKIWLRALVGSPDGKTILRGERLVSPEDAEQAGISLAEELLDKGAR
EILTAVYQGNTAI
>B4SZ46|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella newport (strain SL254)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKY
HSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAG
LKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEE
LLENGARAILTEVYNGETPA
>G4G884|hydroxymethylbilane synthase|EC 2.5.1.61|Natronobacterium gregoryi SP2|TrEMBL
MRTRGTLRLATRGSTLARRQAGLVEEALEDRRYEVELVTVETTGDQIRDELIHRLGKTGA
FVRELDERVLEGDLDGAIHSMKDMPTEQPDDLVTAAVPERGRPGDALVTPDDSSLEQLPR
GATVGTSSLRRRAQLLSERPDLEVAPLRGNVDTRLEKLLAPTLQAEHQKRSEADKERKGN
TGNEDFEPEYERTVDEWFDDLSELERQALGREVETEYDAIVLAAVGLERSGLAHYVDYQQ
LPTGTFVPAPGQGALAVTAADGETAREIREAIDHPRSRVETTVERTLLSELGGGCIAPIG
IYAILQGEYVHANVTVFDRDGEESVIASRDLSVQRHAEAAREFASDLADRGAAELIESAR
KETERDDESTAEPSEGE
>B1WTL1|hydroxymethylbilane synthase|EC 2.5.1.61|Cyanothece sp. (strain ATCC 51142)|TrEMBL
MSPLIVTLIISLPSMVVSTRTIRIGSRKSQLALVQTYWIQEELQKHYPDRQFDVETMSTQ
GDKILDVALAKIGDKGLFTKELETAMLQNQVDFAVHSLKDLPTNLPEGLMLGCVTERVNP
ADALVVNETHQDKQLDTLPEGSVIGTSSLRRLAQLRHHYPHLTFKDVRGNVNTRLSKLDA
GEYDAIILAVAGLQRLDMSDRIHQVIPDDISLHAVGQGALGIECRSGDPEILDLLKVLEH
TETRDRCYAERAFLRQLEGGCQVPIGVNTKIENNILTLTGMVASLDGKTLIKDTIQGEAA
QAEKLGEELALRLRDEGATEILAEIFAQIQR
>D5RNK8|hydroxymethylbilane synthase|EC 2.5.1.61|Roseomonas cervicalis ATCC 49957|TrEMBL
PLRAGSRASPLALRQTAMVLAALGETPCLTVPLSTSGDAEPRRRLAELGGKGLFAKEIHE
ALLDGRIDFAVHSLKDLETELPPGLVIAACLPREDARDALLLAPACPPEERALPLGFLPV
GARIGTASARRAAQLRHLRPDLRFGLLRGNVQTRLHRLEQGDFAATLLAMAGLKRLDLAA
RASRILSPEEMLPAAGQGVIAITARAGNEALREKLAGIDHAATRLAAAAERALLAALEGS
CRTPVGAHATLDAEGRLHLTGLVAREDGTFLLRRRLSGPASEAARIGATLGAELRADSPA
DLLA
>D3HP40|hydroxymethylbilane synthase|EC 2.5.1.61|Legionella longbeachae serogroup 1 (strain NSW150)|TrEMBL
MNSRIIRIATRQSPLALWQANYVRQLLLNKWPKLNIELLPMTTSGDKFLKDKLLAVGGKG
LFVKELEEALLDKRADFAVHSSKDMPAEFPHGLCLAAICKRDNPFDALVSHHYTSLQTLP
ERAIIGTASLRRQSQLLAYRSDLCVKPLRGNINTRLEKLRAGEYQAIILAASGLERMGFT
HVITEQLPTEIMLPACGQGALAIECRTDDQETLALVAELNDPISSLCVHTERQVNAQLGG
NCHIPLAVFCTPIEKNQLLLQAKILTIDGSQTIADTQMGSFAQATNMADRCSQSLIAQGA
ANLLASVSPR
>C6RGE5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter showae RM3277|TrEMBL
MEKLKIATRKSVLAMWQSEHIRDKILSRYPQIAVELTGMKTKGDVILDTPLAKIGGKGLF
TKELEDSMLSGETHIAVHSLKDVPVVFPEGLVLAAICSREDVRDAMLSEKYAKFEDLPEG
ARVGTTSLRRKMQLLAMRPDLEIISLRGNVQTRLRKLKEGEFDAIILAMAGVNRLNLRSE
VAHIVPFELDQMVPAMGQGALGIEAREDSEILNLIEFLKDEKAVIETTVERDFVAMLEGG
CQVPIGVNANLNGDKIEIRAVVGLPDGSESIRENIVAQKSEWKSVGAELGRIFIGKGAKE
LLKRAEEMANI
>B6HJQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255)|TrEMBL
MSTPTPTQKTITIGTRKSKLALLQTNLVLDALKKAFPQYEYKIFSKETAGDLNTTIALRD
FNTKNLWTEELEELMIDGQVDIIVHSLKDVPTTLPSSCKLGPSMPREDSRDVLVVKQGLP
YKSLSEIPAGSVVGTSSIRRTAQLARKYPHLKVQDVRGNIGTRLSKLDAEDSPYACIILA
AAGLLRLDLADRITQYLDSKNSGMLYAVGQGALGIEIRKEDTVLHDMLDKIGHQDTTFSV
LAERSLLRTLEGGCSAPLGVETGWVQNAQGAKQLRMRSVVVSVDGKECAQVELEADVTSA
ESAEAFGITVAKALVADGAGDILQAIQQNKAKETVSTAV
>F9EXZ8|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria macacae ATCC 33926|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKTLYPDCEVEILGMTTRGDQILDKTLSKIGGKG
LFIKELEQALQDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMP
KGAVVGTSSLRREAQLRARYPNLVIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
ERIRLILSEADSLPAAGQGALGIEIAAHRTDLLDVLKPLNHDVTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVILQADAQAPTAYADALGRAVAKKLADDGAQ
ELIEAVLKEQAE
>B3B7J1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC4501|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>A3CU66|hydroxymethylbilane synthase|EC 2.5.1.61|Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)|TrEMBL
MSLRIGTRGSALALAQTNKVVGMLADRGIEAEVVTIATEGDTATGVPLHAIGGQGVFVRA
LDDAILRGEIDAAVHSMKDIPAARPAGLVCCAVLERDSPADFLVHECPLDAVSVIGSSST
RRCAQLLRDAPALEVKQLRGNVDTRLRKLREGQYDAIVLAEAGLQRLGLTLPGEPLPTDR
FVPSPNQGTIAVVCRDDPAVAGAFAALDHAPTRLDVEIERAVMEEVGGGCFTPQGIYCRN
GNLIAEVLALDGSRWERIERHVATVGEAREWGRALRVQAASLIREAHAALGIKP
>D0JJK6|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis (strain D106004)|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>F9YXL9|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes 266|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>F9YXL9|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes 266|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>D6Y3G4|hydroxymethylbilane synthase|EC 2.5.1.61|Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51)|TrEMBL
MSAPLRLGTRKSLMATSQSRRVAERLAQATGRRSELVGITTFGDVSRAHLTQLGGTGVFV
SELRNALIAGEVDFAVHSLKDLPTKGDDRIVIAAIPPRDDPRDAFVGRVPFSELPPGARV
GTGSPRRIAQLRMLRPDLEYVPIRGNADTRLGKVTSGELDGIVLAAAGLGRIGREEAIAQ
VFEVEQVLPAPGQGALAVECRADRADLIELLSAIDDRATRDAVTAERSVLAALEAGCAAP
VGAHASGDGNVLSLTAAVVSVDGRRSVRKSVSGPASAAMELGRDLAAAMLAEGAGTLMRE
QVQ
>E8XMK3|hydroxymethylbilane synthase|EC 2.5.1.61|Rahnella sp. (strain Y9602)|TrEMBL
MLDKIIRIATRQSPLALWQAQYVQSRLMACHPGLQVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELAMLDGRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNQYASLADLP
QGSIVGTSSLRRQCQLRQKRPDLMIRDLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
NRITYALTPEECLPAVGQGAVGIECRLDDQTTRDLLAPLAHRETTLRVQAERAMNMRLEG
GCQVPIGSYAELEGDELWLRALVGAPDGSQMVCGERRGPAANAHRMGVDLAEELLANGAR
EILHEVYQGNVPK
>D7CHT1|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces bingchenggensis (strain BCW-1)|TrEMBL
MNATPPAASGRAHTPAASGRAHTSGSPAPLRLGTRRSALAMAQSGQIADAVRRVTGRPVE
LVEITTRGDVSREDLAQIGGTGVFATALREALLRGEIDFAVHSLKDLPTAQPDDLVLAAL
PAREDPRDALIARDGLTFAELPPGARIGTGSPRRTSQLRAWARSLGLRIETVPIRGNVDT
RIGYVRSGELDAVVLAAAGLARLGRLDEATEILDADHILPAPGQGALAVECAAANAALAA
QLAELDDPLTRVAVTAERSLLAALEAGCSAPVGALADLLGDGQAVTEMRLRGVVGTTDGS
SLVQLSITGPVPTAPGEEAAQLMGHELAAEMLAKGAAGLMGERAH
>A4WPZ3|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)|TrEMBL
MDSANQIGMTHSMPTPAEPLKIGTRGSPLALAQAYETRSRLSAAFSLPEEAFEIVVIKTT
GDKVLDRPLKEIGGKGLFTREIEEALLDGGIDIAVHSMKDMPTLQPEGLILDTYLPREDT
RDAFITYAEGGLADLPQGATVGSSSLRRRAQLLNKRPDLQVVEFRGNLQTRLKKLNDGVA
RGTFLAMAGLNRLKMDDVPRVAIEPEEMLSAVAQGAIGIERRIDDPRTQEMLAAIHDVPT
GHRLAAERSFLLKLDGSCETPIAGLAVLEGDQIWLRGEILRPDGSESISGEIRGGIPDAA
ALGAELASELLGRAPSDFFSWR
>F5S3D4|hydroxymethylbilane synthase|EC 2.5.1.61|Enterobacter hormaechei ATCC 49162|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKQRLEACHTGLRVELVPMVTRGDVILDTPLAK
VGGKGLFVKELELALLENRADIAVHSMKDVPVEFPEGLGLVTICEREDPRDAFVSNRYDS
LDALPAGSVVGTSSLRRQCQLAERRPDLVIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLEERIRVALPPELSLPAVGQGAVGIECRLDDARTQALLAPLNHDDTAVRVKAERAMN
TRLEGGCQVPIGSYAELTGDELWLRALVGAPDGSQMVRGERRGKPQDAEALGVSLAEELL
NNGAREILAEVYNGEPPA
>Q73HL3|hydroxymethylbilane synthase|EC 2.5.1.61|Wolbachia pipientis wMel|TrEMBL
MLVKIGTRGSKLAVAQALEAKQKLLDSFPNLSIEIVKIKTSGDKYANANLAEIGGKGLFI
KEIETELLENNIDMAVHSLKDMPAFFSGGLTIPCVLERLSSCDAFISHKHNSLESLPQQA
TIATSSIRRKVQLLNVRPDLNIVPLRGNVTTRLQNQSFDGIILAEAGLIRLEKHHLITEV
LPPKVMLSAVGQGAVCIQCRRNDVKIIDLLEKINNNMSFIGVKSERSFMKTVNGSCFTPL
AALAEYVSENMLHLRCMLASGKNIYFTERTSFIEDAEKMGMDAGLELKSKCL
>E1EJ85|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio parahaemolyticus K5030|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSNINEL
PQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EDRIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEVRGHRKDGEALGIQLANELLDSGA
RDILTKLYADHD
>F5ZFM5|hydroxymethylbilane synthase|EC 2.5.1.61|Alteromonas sp. (strain SN2)|TrEMBL
MPVEKNRTIRIATRKSALALWQAEYVKAKLLEHHDGIAVELVPMSTQGDRILDTPLAKIG
GKGLFIKELEVAMLEGRADIAVHSMKDLPVEFPEGFGLHAICERENPFDAFVSNHFDNLD
ALPEGAVVGTSSLRRQCQIRKHRPDLKIKDLRGNVNTRLAKLDAGEYDAIILASAGLIRL
GMEERIKTGLPASVSLPAVGQGAVGIECRNDDAELIALLQALNHGETQTRVSAERAMNER
LEGGCQVPIGSFATLDGDSITLTGMVGQPDGSTLLFASATGPTKNAKSIGVEVAEALLEQ
GAGEILSALYD
>H5DRJ7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC10A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F5TV08|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium sp. 434-HC2|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>F5TV08|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium sp. 434-HC2|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>H6QIY4|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia massiliae str. AZT80|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCKIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEAFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKGDNAMLKICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDADPRHLSKLAYREAFEGNTEALATAAYKSDRTDASTGLTYKLPLEV
EFGKMSNIQTDFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>F0E0T6|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas sp. TJI-51|TrEMBL
MSTREIRIATRKSALALWQAEYVKARLEQAHPELRVTLVPMVSRGDKLLDAPLAKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNHFASLEALP
AGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
DRITATISVDDSLPAGGQGAVGIECRSADHAIHALLAPLHHHDTADRVVAERAMNKRLNG
GCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRATAEALGVEVAEHLLGQGAE
AILKEVYGEAGHP
>G2F612|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli XH001|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>Q2KYG4|hydroxymethylbilane synthase|EC 2.5.1.61|Bordetella avium (strain 197N)|TrEMBL
VTLPQRLVIATRASRLALWQAEHVRDRLRDLYPACAVELLTLTTRGDQILDRSLSKVGGK
GLFVKELEHALLDGRADLAVHSLKDVPVDIQAPFALSTVLERADPRDAFVSARYASLDAL
PVGAVVGTSSLRREAQIRAARPDLVVRPLRGNLDTRLGKLDRGEYDAVVLAAAGLERIGY
GDRIRARLAPAQSLPAAGQGALGIEIRDDRDDMRAWLAPLSDASTTACVSAERAVSRALG
GSCQVPIGAYAELHGQTLRIDALVASPDGRRILRASRLGPVAEADSLGMAVAHDLLAQGG
DAILAELLQDDAAS
>E1RG48|hydroxymethylbilane synthase|EC 2.5.1.61|Methanoplanus petrolearius (strain DSM 11571 / OCM 486 / SEBR 4847)|TrEMBL
MSLIAGTRASKLALAQTKRVSRMLYDLEIETQVKKISTSGDNVTNVPLHKVGGQGIFVKA
LDDAILEGEIDFAVHSMKDIPAKRPDGVVTCAILKRDSPADFLVHYCPLKEVKIVGTSST
RRRAQFLRGGLDVEVKELRGNVDTRIRKLKEGEYDAIVLAEAGMERLGLDLPGTRLLPQW
HVPSPNQGIIAVVCRDDPELIKTFEPLNHEQTRMDASVERAVMEEIGGGCYTPQGVFCED
GFLIAEVLSLDGKRWERIEDDGSSVEEARLIGQKLRSIGYDIIEEARLSLGL
>C6BBI4|hydroxymethylbilane synthase|EC 2.5.1.61|Ralstonia pickettii (strain 12D)|TrEMBL
MSSNARPTSRQSQLATTPAAQAPTKLVIASRESRLALWQAEHVRAALQKYYPACDVSILG
MTTRGDQILDRSLAKVGGKGLFVKELEVALAEGRADLAVHSLKDVPMQLPEGFALSTILE
REDPRDAFVSNDYADLASLPAGAVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLGKLD
RGDYAAIILAAAGLRRLGLADRIRSTIAPEESLPAAGQGALGIEIRADREEVRACLAPLH
DAPTALAVTAERAVSRILGGSCQVPLAAFAQWSGAGTLRLRAFVASQDGTRKLAADGEAT
PSTLADADALGVRVAQQMLAGGARDILSMLGADAPPAT
>H5ETA9|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC10D|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F7TTJ4|hydroxymethylbilane synthase|EC 2.5.1.61|Brevibacillus laterosporus LMG 15441|TrEMBL
MKEWKVGSRKSMLALTQTKWVLARLREIDPASSFSITEIVTKGDRILDVTLSKVGGKGLF
VKEIEQSLLEEQTDMAVHSLKDMPAVLPEGLTIGAIPKREDPRDVLISKDGKTLDELKQG
AVVGTSSLRRSSQLLHYRPDLIIKPIRGNIDTRIRKLEEEDFDAIILAAAGLKRVEWKGT
ITQYLDPQISLPAVGQGALAIECRTHDAEMMSLLQRFDHLETRYAVEAERAFLHKMEGSC
QVPIGAYAEVQLDANQKPSISITGMVGSPDGSQLFKATLTGDNPQALGENLAEELLRQGA
REVLAKVLEENRQ
>B5GV35|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)|TrEMBL
MVETEVMRIVSRSSPMALAQVERVRAELAVARPGVRTEVVPVTTSGDRWMGDLAALGGKG
AFTKEVDAALLAGEADLAVHCMKDVPADRPLPAGTTFAAFLRRDDIRDALVHPGGLTLDE
LPDGTRIGTSSVRRIAQLASSHPQLECVPMRGNANRRLEKLAAGDADALLLAVSGLERIG
RTDVISEVLSADVMCPPIGAGVLALQCREEDEETIDAVSGLGDPATHREVTAERMLLHVL
QGHCNSPIAGYARAERGGELSLRAKVFTPDGKRVLNAHEWAGPLDPATLGTSVAVALLRQ
GARELIDGIPH
>C9LXX8|hydroxymethylbilane synthase|EC 2.5.1.61|Selenomonas sputigena ATCC 35185|TrEMBL
MKKDTIVIGTRSSKLALWQADYVEAKLRERYPELHVVQKRMTTKGDRVLDAPLAKIGGKG
LFTKELEQAMLAGEIDLAVHSLKDMPTELPEGLMLAAVTERFDPGDAVVSPRYQTLANLP
QGAKVGTSSLRRRAQLLAKRPDLEIVSLRGNVNTRLKKLEEENFDAIILAVAGLKRLGFH
DRITEILPREICLPAVGQGALAIEARADDEATLSLIAFLDDAATRAAARAERAFLARVEG
GCQVPVGVYAEAADEALEMEAVIASIDGERLYRKKKAGSALDAEKIGRALAEELLAMGGK
EILQELGLLQP
>E8D353|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. MB102109-0047|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>E6M6X7|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus lugdunensis M23590|TrEMBL
MRKLVVGSRRSKLALTQSKQFIDKLKEINPDLEIEIKEIVTKGDQILDKQLSKVGGKGLF
VKEIQHELFNKEIDFAIHSLKDVPSILPEGLTLGCIPDRENPFDAYIAKNHTPLDQLPDG
SIVGTSSLRRGAQILAKYPNLEIKWIRGNIDTRLHKLETENYDAIILAAAGLKRMGWSDD
IVTTYLDKDVLLPAIGQGALGIECRSDDVELLALLNQVHNQQVADCVTAERTFLAAMDGS
CQVPIGGYATNKTNGDIEFTGLIMTPDGKERYEHTEIGNNPIELGNKVSDVLIEQGAYEI
IRKLNDQQLH
>E4S6S3|hydroxymethylbilane synthase|EC 2.5.1.61|Caldicellulosiruptor kristjanssonii (strain ATCC 700853 / DSM 12137 / I77R1B)|TrEMBL
MKKLRIGARDSRLSRIQVDIVARKIKQTLGIECEFVPIKTKGDIDKTKSLKEFKSPGVFV
KEIELALLSREIDLAVHSLKDLPCEMDSNFEIVAVVEREDPRDVLVSKDGLGFYQLKSNA
KIGTSSLRREVHLKNLREDIQVINIRGNIETRLSKIQSEGLDGIVLAYAALKRLKLDSYV
SYIFDINEITPCPGQGAICIECLKDSPYKSILSKINDADAYIQTQFERLVLKFLGGGCHS
SIGVFCKTDQNKIYAFASLLRGDKLVKASIEGNKDDFLSLANKLSKMLES
>B8KD38|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio parahaemolyticus 16|TrEMBL
MVTKGDIILDTPLAKVGGKGLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICE
REDPRDAFVSNTYNNIDELPHGAVVGTCSLRRQCQIKEYRPDLVIKELRGNVGTRLGKLD
AGEYDAIILAAAGLKRLELEERIRSFIEPEQSLPAVGQGAVGIECRLDDERLIKLLEPLN
HQDTADRVLCERAMNLTLEGGCQVPIGSYALLDGDEIWLRALVGEPDGSEIVRGEIKGAR
ADAENLGVTLANQLLDKGAREILTKLYADHE
>B1BTU7|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium perfringens E str. JGS1987|TrEMBL
MELIIATRKSKLAQVQTEKVMELLKEKENVDSKKLLVMTEGDRRLDVSLNKIGGKGLFVK
EIELALLNKEAHGAVHSMKDVPFELPSEFELVAMPEREDIRDAFVSLNGSTLSNLRKGAR
IGTSSIRRAEQLKLFRDDLEIVPIRGNVQTRIKKITEENLDGIILAAAGLKRLGMEDVIS
DYFDPKVFLPAIGQGALGIECLKGGEFNKYFKALDSKEVRTTVEAERSFMKVLNGGCHSL
IGAYSEVKDNDLYMIGTFTVNNRIVKKDILGNKEDNILLGKKLAEKILGEV
>I2ZGI7|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW07793|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>Q2JXL5|hydroxymethylbilane synthase|EC 2.5.1.61|Synechococcus sp. (strain JA-3-3Ab)|TrEMBL
MRIASRKSELALAQTYWVMGQLQAHHPGLPLELHTLSTQGDIILDVALAKIGDKGLFTKE
LEVSLLNGSSDLAVHSLKDLPTRLPEGLVLGAITQREDPLDALVLREELRGYQLATLPAG
TVIGTSSLRRLAQLRHAFPHLQFKNVRGNLNTRLAKLDRGEYDGLILAVAGLKRLGQEQR
IHEVLDPSVSLYAVGQGSLGIECRQGDERILELIRPLADAEATARCLAERAFLRALEGGC
QVPIGVHSQVQGEELHLTGMVADLEGRQLIRDTQTGSTADPEAVGMALAEKLKRQGADEI
LQAIFAQARR
>D9PXA9|hydroxymethylbilane synthase|EC 2.5.1.61|Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg)|TrEMBL
MIAGTRGSRLALVQTDHVIDMLSEICGERIERRIIKTKGDRIKDSQLYSMDSRGLFTREL
DIAVLEEEVDFAVHSLKDVPSDLDPELVIAAVPPRESPNEVLVSRFDWDELPPAAKLGTS
SLRREAFCNHHQKNFKMEPLRGNIDTRIRKVMEGEVHATIMAEAGLKRLGLENYIKKRFT
LEYFTPAAGQGALAVITRRDSELMVSIEKITHYPSHQEVTAEKTLLRELGAGCQCPLGVI
ARASDGKINLYAVLLTRDGEILKRVNVKGSVDKAEEIGKKAAKEMEDYI
>A3WIA8|hydroxymethylbilane synthase|EC 2.5.1.61|Erythrobacter sp. NAP1|TrEMBL
MAQAFETRERLCKAHGWAEGEVELVPVVASGDKVLDRPLAEIGGKALWTKELDAWLAEGK
IDVAVHSAKDVETIRPDAFRFAAFLPRADRRDALVGAASIADIPRGATVGTSAPRRASQL
LNLRPDCKVVTFRGNVATRLGKLEAGEADVTFLAAAGLERLGQSEVGAPLETGDWIPAAA
QGVIALECRADDDEAGELLAAIDHAATRAELEAERALLAKLGGTCHSPVAVLCSGDAGEL
TMRAALFSPDGSERVDGEASFSAGDHAPVHALAADLLHRATPAIAEHFGGEG
>Q0SYZ3|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri serotype 5b (strain 8401)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGEAPA
>I2RW11|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 97.0246|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>B7WYK9|hydroxymethylbilane synthase|EC 2.5.1.61|Comamonas testosteroni KF-1|TrEMBL
MKFSASSPASIVIATRESQLAMWQAEHVQAILRGRGHSVDLLGMTTKGDQILDRALSKVG
GKGLFVKELEVALEEGRADLAVHSLKDVPMELPEGFVLACVMTREDPRDAFVSNRYASLD
ELPQGAVVGTSSLRRQALLQALRPDLKIEALRGNVNTRLRKLDEGQYDAIVLAAAGLMRL
EMSDRIRARFDPAQMLPAAGQGALGIEVRADRQDIIDALAPLAHMPTWLTVTAERAVSRC
MGGSCSMPLAAYGRFESDILHMDAAWGDMEGDKGLVRVQASASVTDFASANALGEQLAAQ
LQAAGAVPAAPKQD
>E1DM57|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio parahaemolyticus AN-5034|TrEMBL
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGK
GLFVKELEVAMLEGRADLAVHSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSNINEL
PQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKLDAGEYDAIILAAAGLKRLKL
EDRIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEVRGHRKDGEALGIQLANELLDSGA
RDILTKLYADHD
>A6W5L8|hydroxymethylbilane synthase|EC 2.5.1.61|Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)|TrEMBL
MTRPLRLGTRRSALATTQSSWVADLLRRGGSPVELVEITTRGDVDRAPLAQIGGTGVFVS
ALRDALLAGEVDLAVHSLKDLPTSAADGLALAAVPGREDPRDVLVAAGGATLADLPRGAR
VGTGSPRRRALLLALRPDLDVVAVRGNVDTRIGFATGGELDAVVLAAAGLARTGRLHEAS
ELFAPEVFVPAPGQGALAVECRADDAEVLAALAALDVPAVRWAVAAERQVLASLEAGCSA
PVGAHAAGGVLHVAVEDPDGALVRRAVPAAGLDDEGAARRLGASVAADLLEHELAQTPVA
VGGGAQENHPQDRPVDGPRPDPESGS
>E7VUX1|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 495297-3|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>D9Q2S0|hydroxymethylbilane synthase|EC 2.5.1.61|Acidilobus saccharovorans (strain DSM 16705 / VKM B-2471 / 345-15)|TrEMBL
MIKLKVATRGSKLSLEQVVIAMRFLEQRLGERVEYEPVIVKTRGDVMQDRPLFSIGVKGV
FEKEVNRAVLNGEADVAVHSMKDLPSQLEEDLEIAMVPPREVPNDSLVIGAGSPEVTGVE
DVPSGLSVGTSSVRRIAFLRHYNRNVITKVVRGNVDTRIAKLNRGEVNYLLMAEAGLRRL
NIPQKRVMLPLDKFPPEPGQGIIAVVAPSSSPLFDLLRRASDEVTYAMAMAERKFVELIG
AGCHTPIGAVSILEGGRLAMIAAAASPDGEVMNFARASGSLGEPERIARELVENLKVP
>H7WAJ1|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter coli H6|TrEMBL
MKELVIATRKSQLALWQSEFIADFLNKTHGIAVRLEGFKTKGDVLLDSPLAKIGGKGLFT
KELEESMLRNEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGA
KIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNGDFDAIILAMAGIKRLDLDKQV
NFVYTFSKDELIPAASQGALGIESIDDEKFLKFLKCLNDDNALIETTIEREFISTLEGGC
QVPIGINAELLGDEICVRAILGLPDGSEILKEKRMIKKSDFKGFGESLAKEFIAKGAKEL
LKKAESMI
>D4L743|hydroxymethylbilane synthase|EC 2.5.1.61|Ruminococcus bromii L2-63|TrEMBL
MTIKIGTRKSRLALAQTEMLIKTLKNRFPNVKIETVYISTTGDKTLDKPLTALGGKGVFI
KELEMSLLSGETDVAVHSAKDLPTKIADGLEISAVLPRGSYGDVFVTRNNFETKDGFVIG
TGSLRRKLFAEKIYPNAKFKDIRGNVDTRLKKLLNGEYDALVLAKAGLERLDLCNGEDYT
VTPFDADEFLPAPCQGIVAIESRKNSEVSKMLAEISDKNTMLSFETERQVLHSLNADCST
PVGAISKVENDRITLSLSADCKKTVSGTDEISNRIKLAKRLVSEIE
>G8FBP2|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni D2600|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>H7F2J4|hydroxymethylbilane synthase|EC 2.5.1.61|Listeriaceae bacterium TTU M1-001|TrEMBL
MKREIIVGSRRSKLALTQTNQVIEALKVKFPDVTFKVYEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALVDKKIDFAVHSMKDVPSLLEEKLVIGAIPKRESPFDCVIFAERSHLDDLPQ
GAVIGTSSLRRAAMLKRYREDFQIKSIRGNIDTRLKKLVEDDFDAIVLAEAGLARMGWLE
NPELKRQRLNEQICLPAVGQGALAIECREEDIEVRSMLQEIHDDETAFCVRAERTFLKDL
NGGCEIPIAGYATHSSNGLSFTGFVGSEDGKTRLEAQTNGTNPEKVGAEAAEILLQKGAK
KWIDALRPS
>Q3ISY1|hydroxymethylbilane synthase|EC 2.5.1.61|Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)|TrEMBL
MTETIRLATRGSDLALRQAQRVADALDSRRRTVELVEVETTGDAVRDELIHRLGKTGAFV
RSLDEKVIDGDVDAAVHSMKDMPTEFPDELVVAGVPERASPGDVLVTPDGDTLDSLPDGA
TVGTSSLRRKAQLLAARPDLDVQPLRGNVDTRVQKLLAPSLQAEHERRLEAEDDEGEAED
EDGDDADRYDRPPEEWFDDLAEIERQALGREIETRFDGIVLAEAGLQRTGLLAQVETERL
PETFVPAAGQGALAVTACDGDVGQTLQNELDHPRTRVETTVERTILGTLGGGCVAPVGIH
AVVRGEYVQASVRVLSQDGTEEIEATRDLPIERHPEAAREFADELADRGAADLIQRARRD
A
>B5CH91|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Schwarzengrund str. SL480|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>E0DC46|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium matruchotii ATCC 14266|TrEMBL
MPIIGTRGSLLATTQAGHVRDALTSHGYPSELRIVTTTGDVNLAPVERIGVGVFTQALRD
SLLAGECDIAVHSFKDLPTAVDERFHLVVPHRENARDCLIARNNLTLAELPTGAVVGTGA
PRRIAQLKALRPDIHTVPLRGNIDTRMAKVHDGELDAVVLAYAGLSRVHRADEATEVFDP
LEFLPAPAQGALAVECRADDADTIAAITTIADPKAYACAHTERVVLARLEAGCTAPVAAY
ATVAADNIMTLHAAVIAVDGSATLRATAAGPIDTAENLGMTVARALLDDGASSLLAAS
>E0DC46|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium matruchotii ATCC 14266|TrEMBL
MPIIGTRGSLLATTQAGHVRDALTSHGYPSELRIVTTTGDVNLAPVERIGVGVFTQALRD
SLLAGECDIAVHSFKDLPTAVDERFHLVVPHRENARDCLIARNNLTLAELPTGAVVGTGA
PRRIAQLKALRPDIHTVPLRGNIDTRMAKVHDGELDAVVLAYAGLSRVHRADEATEVFDP
LEFLPAPAQGALAVECRADDADTIAAITTIADPKAYACAHTERVVLARLEAGCTAPVAAY
ATVAADNIMTLHAAVIAVDGSATLRATAAGPIDTAENLGMTVARALLDDGASSLLAAS
>Q4WVE1|hydroxymethylbilane synthase|EC 2.5.1.61|Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)|TrEMBL
MASAPPSSEAANSSSRRTFTIGTRKSKLALLQTDLVVAALKKSWPEYTFQIHSQETAGDK
NTVIALREFTTKNLWTQELEELLMAGDVDLIVHSLKDVPTQLPPSCTLGPMMEREDTRDV
LVMKKGLPNMSFSEMPAGSVVGTSSIRRTAQLARRYPHLKVQDVRGNIGTRLAKLDAEDS
PFTCIVLAAAGLLRLGMEDRISQYLDSKNGGMLYAVGQGALGVEIRKDDKVLRDMLNSIG
HQKTTLACLAERSLLRTLEGGCSAPLGVETEWVQDSDRSSKLRMRAIVVSVDGRESAEVE
VDGSVDTAESAEEFGVTVAKALVEKGAGEILAEIQRKKLTP
>G8VC59|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes TypeIA2 P.acn33|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>G8VC59|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes TypeIA2 P.acn33|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>E8VZ92|hydroxymethylbilane synthase|EC 2.5.1.61|Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)|TrEMBL
MTENSPLGGETTTPLRLGTRRSKLAMAQSGMVADAVREVTGRAVELVEITTYGDISREHL
AQIGGTGVFVAALREALLSGEVDFAVHSLKDLPTTQPEGLVLAAVPPREDPRDALVARDG
LTFGQLPAGARIGTGSPRRMAQLNAYARSHGLDIETVAIRGNVDTRIGFVRSGELDAVVL
AAAGLSRLGRTDEVTDFLPVDTVLPAPGQGALAVECAESSADLAAALAELDDPYTRIAVT
AERALLNALEAGCSAPVGALADLLAEGQVVNELRLRGVVGSTDGTSLVQLSITGPVPTSH
DDAAALGRELAAEMLAKGAAGLMGERAL
>F9NRQ9|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes SK182|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>F9NRQ9|hydroxymethylbilane synthase|EC 2.5.1.61|Propionibacterium acnes SK182|TrEMBL
MSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASLAAMGGIGVFASA
IRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASV
GTGSPRRAAQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLA
RLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAATAER
AVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVREQVSVELPAEVEP
ALAAAHTLGVTAAEELLDDGAADVADLKASGSTR
>H8BLU5|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 87459|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESILRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>I4GKQ5|hydroxymethylbilane synthase|EC 2.5.1.61|Microcystis aeruginosa PCC 7941|TrEMBL
MSVSSPPRSLRIGSRKSQLALVQTYWVQAELSKHHPHRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVGMLDRSIDLAVHSLKDLPTNLPEGLILGCVTERVNPADALVVNSKNQD
YQLDNLPEGSVIGTSSLRRLAQLRHHYPHLTFKDVRGNVNTRLAKLDAGEYDGIILAVAG
LERLGLGDRVHQVIPAEISLHAVGQGALGIECRDADPEVLEVLKVLEHAPSRDKCYAERA
FLRELEGGCQVPIGVNTAIEDGILTLTGMVASLDGKRLIKDSVSGDPSHGEALGRDLAHK
LRDAGAGEILAEIFAEVGR
>D3T6R3|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoanaerobacter italicus (strain DSM 9252 / Ab9)|TrEMBL
MKKVIKVGSRSSELALVQTQMVINEIKKFRQDFEFEIVKITTQGDALIDKPISEIGGKGV
FVKEIESALLKGEIDMAVHSLKDMPYETPEGLKLIPVLKREDPRDVFISKDGTQFMNLKE
GAKIGTSSLRRQVQLKDLRSDMQTIPIRGNIKTRLRKIEELNLDGIVLSAAGLHRLGLES
IITEYFPPDVVVPAPCQGILAVEIAESFDNIFQEFYSYIVDRRTFFEASIERELLKVFGV
NCRQPFGAYAQYRKERDEEKINIKVVYQKEDKLLKSEVTGLIEETDKMIEKLIEEFGGI
>D8GQU0|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC)|TrEMBL
MNFKIATRKSKLAQTQTEIVMDILQKDYNAKCEKVLIETMGDKRLDIALNKIGGKGLFLK
EIELALLKDEADAAVHSMKDVPFDVPEDFEIAAIMQREDVRDAFVSKDKVPFDELPKGAK
IGTSSNRRAEQLKILRPDIEIAPIRGNIQTRISKIESQNLDGIVLAAAGIKRSHLEELVT
EYFKVEDMVPAIGQGALGIETKKDSKNKSFFSKLDDENTRICVEAERSFMRTLNGDCHST
IGAYAKIDKDTINIMGMFMVGNKLIKKDVTGNKEDYMVLGEKLAKMILKA
>A4SWL0|hydroxymethylbilane synthase|EC 2.5.1.61|Polynucleobacter necessarius subsp. asymbioticus (strain DSM 18221 / CIP 109841 / QLW-P1DMWA-1)|TrEMBL
MSQTLNSSSSNATPAAPERLVIASRESRLAMWQAEHVRDCLKSLYPQCDVQILGMTTRGD
QILDRALSKVGGKGLFVKELETALEDGRAHLAVHSLKDVPMVMPEGFDLACVMAREDARD
AFVSNDYASLEELPKGAVVGTSSLRREAVLRAKFPHLEVHPLRGNLDTRMGKLDRGEYQA
IILAAAGLKRLGLESRIRAYLPYDPYTPAAGQGALGIETLSKHPSIKHWLAPLNDLPTLL
AVSAERMVSRQLGGSCEVPLAAHAVWDNNQMNIRSFVASVDGKAICLADGVGQVHTIEEA
EALGLAVAQDLLAQGAADLIPHIPK
>G7I110|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium casei UCMA 3821|TrEMBL
MSETTQDKPLKKIGTRGSKLATTQAGHVRDWITANGTPSELHIVTTAGDVNMAPVERIGV
GVFTHALREALHERECDIAVHSFKDLPTAPDERFHLIVPTREDNREALIARDGLTLEQLP
KGAKVGTSAPRRVSQLKALRPDLDIRPLRGNIETRMSYVTDGELDAVMLAYAGLVRAGYA
DRATEVFSPDVIMPAPAQGALAVEVNASDAELVNAVNSVSDAKAGLQAAGERAILRRLEA
GCTAPVAATSVIDGDMITVHGGVFALDGSKQMVAAETGPLENAYDLGVKVAESLLEQGAS
EILDAS
>G7I110|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium casei UCMA 3821|TrEMBL
MSETTQDKPLKKIGTRGSKLATTQAGHVRDWITANGTPSELHIVTTAGDVNMAPVERIGV
GVFTHALREALHERECDIAVHSFKDLPTAPDERFHLIVPTREDNREALIARDGLTLEQLP
KGAKVGTSAPRRVSQLKALRPDLDIRPLRGNIETRMSYVTDGELDAVMLAYAGLVRAGYA
DRATEVFSPDVIMPAPAQGALAVEVNASDAELVNAVNSVSDAKAGLQAAGERAILRRLEA
GCTAPVAATSVIDGDMITVHGGVFALDGSKQMVAAETGPLENAYDLGVKVAESLLEQGAS
EILDAS
>G7Z869|hydroxymethylbilane synthase|EC 2.5.1.61|Azospirillum lipoferum (strain 4B)|TrEMBL
MTTHPLRIGTRGSPLALAQAHETRDRLIAAHPQLAAPGAIEIVVFKTTGDRILDRTLAEA
GGKGLFTKELEEALFDGRADLAVHSMKDVPTQLPDGLEIATLLPREDPRDAFFARSGGGL
ADLPAGAVVGTAGLRRQAQVLELRPDLTVIPLRGNVQTRLSKLDAGEVDATLLALAGLRR
LGLTDRITAVLEPETMLPAVAQGAIGIEIRSADDATRALLAPLNCAETMVRVTAERALLS
ALDGSCRTPIAALAMLDGEDLHLRAKVLSTDGRIIFRAERRGKAADAESLGADAGAEIRA
QLPPDFFAAAPH
>E4N8T9|hydroxymethylbilane synthase|EC 2.5.1.61|Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)|TrEMBL
MIELVVGSRASQLARAQVKEFLAPLRARFPEVAFRHRVILEDGDLDRKSDLRAVSERGGG
SAFAGRQAAALLDREVDVVVHSLKDLPTADPDGLLLLPSPPRADVRDALCGAPLAGLPTG
ARVGTSAARRIAQLLYVRPDLAPERIRGNVPTRLTRLRTLDAVVLAAAGLHRLGRDGEIA
ELLPLAQFPPSPGQGALGIQVRADDAMARELLAGTGDPVTDAEVRAERAMLAELHGGCSV
PVGAHATTADGILTLHGQVTTPRGTRQIEARLSGTSAAPEKLGRAVAGLLLDQDAECLLR
GQAH
>B9Z5H1|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudogulbenkiania ferrooxidans 2002|TrEMBL
MDKIVIASRESKLAMWQAEHIKARLEQLYPQLAVEILGMTTQGDQILDKTLSKIGGKGLF
VKELELALQEGRADLAVHSIKDVPMNLPEGFALAAICEREDPRDAFVSNTYASLSELPDG
AVVGTSSLRRESQLRARFPRLTIKPLRGNVQTRLRKLDDGEFDAIILAAAGLKRLELSAR
IRCELAPSESLPAVGQGALGIEIRADRADLMQLLAPLDHADTHACVSAERALSRVLGGSC
QIPLGGFATLSDDVITLGGFVAHPDGSVMLTASASAPREYADALGRAVAQKLLDAGAAPL
IQAVIDEGQGR
>B9Z5H1|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudogulbenkiania ferrooxidans 2002|TrEMBL
MDKIVIASRESKLAMWQAEHIKARLEQLYPQLAVEILGMTTQGDQILDKTLSKIGGKGLF
VKELELALQEGRADLAVHSIKDVPMNLPEGFALAAICEREDPRDAFVSNTYASLSELPDG
AVVGTSSLRRESQLRARFPRLTIKPLRGNVQTRLRKLDDGEFDAIILAAAGLKRLELSAR
IRCELAPSESLPAVGQGALGIEIRADRADLMQLLAPLDHADTHACVSAERALSRVLGGSC
QIPLGGFATLSDDVITLGGFVAHPDGSVMLTASASAPREYADALGRAVAQKLLDAGAAPL
IQAVIDEGQGR
>B9Z5H1|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudogulbenkiania ferrooxidans 2002|TrEMBL
MDKIVIASRESKLAMWQAEHIKARLEQLYPQLAVEILGMTTQGDQILDKTLSKIGGKGLF
VKELELALQEGRADLAVHSIKDVPMNLPEGFALAAICEREDPRDAFVSNTYASLSELPDG
AVVGTSSLRRESQLRARFPRLTIKPLRGNVQTRLRKLDDGEFDAIILAAAGLKRLELSAR
IRCELAPSESLPAVGQGALGIEIRADRADLMQLLAPLDHADTHACVSAERALSRVLGGSC
QIPLGGFATLSDDVITLGGFVAHPDGSVMLTASASAPREYADALGRAVAQKLLDAGAAPL
IQAVIDEGQGR
>B9Z5H1|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudogulbenkiania ferrooxidans 2002|TrEMBL
MDKIVIASRESKLAMWQAEHIKARLEQLYPQLAVEILGMTTQGDQILDKTLSKIGGKGLF
VKELELALQEGRADLAVHSIKDVPMNLPEGFALAAICEREDPRDAFVSNTYASLSELPDG
AVVGTSSLRRESQLRARFPRLTIKPLRGNVQTRLRKLDDGEFDAIILAAAGLKRLELSAR
IRCELAPSESLPAVGQGALGIEIRADRADLMQLLAPLDHADTHACVSAERALSRVLGGSC
QIPLGGFATLSDDVITLGGFVAHPDGSVMLTASASAPREYADALGRAVAQKLLDAGAAPL
IQAVIDEGQGR
>E8DQ23|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. MB111609-0052|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>F6B6M5|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfotomaculum carboxydivorans (strain DSM 14880 / VKM B-2319 / CO-1-SRB)|TrEMBL
MKRKIKVGSRDSALALWQTRWVVAQLEQQNPHLSFEIVTMKTKGDKMLDVALAKIGDKGL
FTKELELAMLNKEIDFAVHSLKDMPTALPAGLTIGAVCKRDNSGDALISKDGRKLAELPQ
GARIGTSSLRRCAQLLNYRPDFRLEALRGNLNTRMKKMASQQLDAIILAAAGIYRMGWSD
MIAEIIPFNVCLPAVGQGAIAVECREDDIEINQLLQGVEHKPTRVATDAERSLLRRLEGG
CQVPIGAYGEVIEDRLSLQAIVATLDGQRLIRAQGEGALNQAEELGIEVADKLLSMGGKE
ILQQVRSGD
>B5KCE9|hydroxymethylbilane synthase|EC 2.5.1.61|Octadecabacter antarcticus 238|TrEMBL
MDFELPSPAAPLKIGTRGSPLALAQAHETRARLMIAFDLPESAFEVCVIKTSGDDRSLID
ADIPLKVIGNKGLFTKEIEEAMLAGRIDIAVHSTKDMPVAQPDGLVLNVFLPREDARDAF
VSVKYAGIADLPEGAIVGTSSLRRRAQLLVKRPDLTVVEFRGNVQTRLKKLADGLADATF
LAMAGLNRMGMHDAAIGAIDLDDMLPAIAQGTISIERRVDDLRARDMLAAIHNVQAGQQM
AAERAFLAALDGSCETPIAGLAMIDCDQMWLRGEILKPDGSQVFTGERRGLVSEGAAMGM
ELAQELLGQAGPDFFEAVQAG
>F8E8Q3|hydroxymethylbilane synthase|EC 2.5.1.61|Flexistipes sinusarabici (strain DSM 4947 / MAS 10)|TrEMBL
MKKLTIATRSSQLAVWQADFIKNEINKKYPDVTIELKKIKTKGDKILDTPLAKIGGKGLF
VKEVENALYERKADIAVHSMKDVPSEMPEGMELFVTPKRETPYDAFLSINYNSIDELPRG
AVVGTSSLRRMVQIRKRRPDLKIENLRGNINTRIKKLEDGMYDAIVLAKAGLVRVGFFQH
LKQTLTEDIMIPAVCQGTLGIEVREDDMESKELLKFFYDEETYIRTKAERAFLKTLEGGC
QVPIAGYSILNGSKLKLMGMVSSLDAKEYIYREVEDSVENAESMGISLAKEILNAGGREI
LANIYHEE
>E0DXE0|hydroxymethylbilane synthase|EC 2.5.1.61|Brucella sp. NF 2653|TrEMBL
MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPL
SEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSA
RRFMDLPQGAIVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVGGTFLACAG
LRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDALLAPLAHRETQIALACERA
FLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEEAVSDAAALGTDAANR
VRAMAGPHFFDGWQ
>B5QVJ1|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enteritidis PT4 (strain P125109)|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHS
LDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLK
RLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELL
ENGARAILTEVYNGETPA
>F7YD38|hydroxymethylbilane synthase|EC 2.5.1.61|Mesorhizobium opportunistum (strain LMG 24607 / HAMBI 3007 / WSM2075)|TrEMBL
MQTTLKIGTRGSPLALAQAHETQARLMAAHGMPAEAFEVVVISTSGDRIQDRPLSEAGGK
GLFTKEIEEALLAGAIDIAVHSSKDMPTQLPDGLELSAFLSREDARDAYVGKATKTIADL
PRGAKVGSSSLRRQALIRRMRPDLDVVMFRGNVQTRLRKLDEGVAAGTILAYAGLKRLGL
DHVVTDLIPLDVFPPAPGQGAIGIETRIGDRAVEKMLVAIHDVPTGQALACERAFLAALD
GSCRTPIAGYAAIEGGKLSFAGLIISPDGTQSHTIDLQGPAQDAALIGTEAARTVRAKAG
EKFFDGWL
>E8Q6J1|hydroxymethylbilane synthase|EC 2.5.1.61|Blochmannia vafer (strain BVAF)|TrEMBL
MNTKFLRIATRKSRLAICQSEYVCNELKRFHPNIKIKLVPIVTTGDKFFNSTTKIKIKKG
AFIKELEYALIENRADIAVHSMKDMTASLPNELILPILCKRIDPRDAFVSIKYSNIDMLP
SGSIIGTSSLRRQCQIQARRSDLTLHNLRGNIDTRIKKLHQGKYDAIILAVAGLNRLHLT
QYIKTYINPKDLLPAMGQGAIAIECRKKDIDTLSLLSPLYHQETSLRIQSERAVTTYLEG
YCQFPIASYSEIHNHQIWLRALIGLPDGSKIIRTEGRAPFDQAEKLGLFLAKKLLNQFKE
TTQLDINAIK
>B6IPP7|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodospirillum centenum (strain ATCC 51521 / SW)|TrEMBL
MKQPLRIGTRGSPLALAQAHETRRRLAEAHPHLAEPDAIEIVVIKTTGDRILDRTLMEAG
GKGLFTKEIEEALQAETIDLAVHSMKDVPTWRQTGLQLTAMLPREDPRDAWFCRHGCGLD
ELPAGAVVGTASLRRQAQILARRPDLKVVPFRGNVQTRMTKLAEGQVDATLLALAGLRRL
GLVEHMTAAIETDVMLPAVAQGAIGIETRAADDVTNALVAALNHAETMTRVTAERGVLAT
LDGSCRTPIAALAELPGDGSLTLSALVIRPNGQEFYRTERRGDPDDAEAMGIDAGQELKA
KLPPDFFAVSGAIEGPAGPGSAI
>D0MJW6|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10)|TrEMBL
MPEPTLILGTRGSALALRQATLIRSFLEARGVSVQVEIIRTTGDHIQDVPLAKIGAKGLF
TKELDQALLEGRIDLAVHSLKDLPTEMPEGLVVAAVPERAPPWDVFVAHPDFAGRLEDLP
TGAVVATSSLRRQAQLRAWRSDLQVVPVRGNVDTRLRKLEAEGWHGLILAEAGLQRLGLL
ERVRQRIAPEILLPAVGQGALGVVCAEANRRVRALLQALHHAPTAAAVRAERALLHALQG
GCQVPVAALAAVEADGTLVLRGRVVSLDGRQLVEGVQRGAMAEPEAVGEALAETLLQQGA
RAILEEIRGQHP
>G2H4U0|hydroxymethylbilane synthase|EC 2.5.1.61|Desulfovibrio sp. A2|TrEMBL
MKKLVIATRGSKLALWQAEHIKSCIEGKHPGVSVELLVLKTRGDIILDVPLAKVGGKGLF
VKEIEEALLDGRADLAVHSMKDVPMELPEGLVLGIIPEREEPSDTFLSVHHASLAALPHG
ATVGTSSLRRQSQLLALRPDLNVVSLRGNVDTRLRKLSEGQFDAIIMATAGMKRLGLSAP
KSEVLGPPAFLPAVGQGALGIEFRADRADLHDLLAFLEHTPTRIRVEAERGFLAGLQGGC
QVPIAGHAVMTGNDTFTLEGLVADLTGTRVIRRTMNGKSAPDGAQARTVGLDLAAQLVAD
GAGAILAEVYGNGEAVN
>I5NXC1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW06591|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D4LHT3|hydroxymethylbilane synthase|EC 2.5.1.61|Ruminococcus sp. SR1/5|TrEMBL
MKTTGDIILDRTLDKVGGKGLFVKELDKALIDGRSILSVHSLKDMPMEVPEELPLLAFSK
REDPRDVLVLPEGASELDKSKPLGCSSLRRTLQLKKLYPDMDVRSIRGNLQTRLRKLDEG
QYSALILAAAGLKRLGLGSRINRYFTADEIIPAAGQGILAVQGRKGEAYDFLEGYCDKDA
WTAGSAERAFVKLLDGGCSSPVAAHAEILGDEIYLRGLYYNEKDGSYVTGTLRGNKADAE
SLGRELAETLRKKGENR
>I6ITQ5|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis PY-42|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>D4YXR8|hydroxymethylbilane synthase|EC 2.5.1.61|Sphingobium japonicum (strain NBRC 101211 / UT26S)|TrEMBL
MQKPSRPLRLGTRGSPLALAQAHMTVAALRARHGWDEGAVEIVVVQTSGDRIQDRALADI
GGKALWTKELDRALASGEIDFAVHSMKDVETIRPAEIRIAAMLPRADVRDRLVGADDFAA
LPERPVVGTSSPRRAAQVRRLRPDAQVVLFRGNVATRLARLDRGEAHATLLAAAGLDRLG
QGDVGVAIPVDVMLPAPSQGAVGIETLSGDEAMLDLLAAISDADTFDCVMAERAVLAGLG
GTCHSPIAAFARLEDGQVRLRAEIISPDGRETVGETARIERGDAAAAEAMGRGLLDRASP
ALRLLFEA
>C2CPP8|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium striatum ATCC 6940|TrEMBL
MFKIGTRGSKLATTQSGHVREWLKANGFESELHIVTTHGDVNMAPVERIGVGVFTQALRE
ALYGGECDIAVHSFKDLPTAADERFLLVVPERQDVREALVARDGLTLAQLPEGARVGTSA
PRRISQLKAMRPDLDIQPLRGNIDTRMGKVTSGELDAVVLAYAGLVRADYQDMASEVFAP
DTFMPAPAQGALAIEAVKDSAAARAIETLIDEQASAASLGERTVLSRLEAGCTAPVAATS
TIENGQLTVRGGVFALDGSRQLLASATGPLSDAAQLGSAVSEELFSRGAAELLGN
>C2CPP8|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium striatum ATCC 6940|TrEMBL
MFKIGTRGSKLATTQSGHVREWLKANGFESELHIVTTHGDVNMAPVERIGVGVFTQALRE
ALYGGECDIAVHSFKDLPTAADERFLLVVPERQDVREALVARDGLTLAQLPEGARVGTSA
PRRISQLKAMRPDLDIQPLRGNIDTRMGKVTSGELDAVVLAYAGLVRADYQDMASEVFAP
DTFMPAPAQGALAIEAVKDSAAARAIETLIDEQASAASLGERTVLSRLEAGCTAPVAATS
TIENGQLTVRGGVFALDGSRQLLASATGPLSDAAQLGSAVSEELFSRGAAELLGN
>C8TYQ4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O103:H2 (strain 12009 / EHEC)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B0QP38|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus anthracis str. A0442|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASYKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAVNKGQQ
>B6KD85|hydroxymethylbilane synthase|EC 2.5.1.61|Toxoplasma gondii|TrEMBL
MTLLREQRSAGAALRLSWVAFLFAFLVLLRDSLFKESYETPAVLLFAAARLLAPPLTPRA
GQGGASSASSSSRLTPSARFPAASWSSSAALVSLLSPPASSRASPSRRDADAPSPSFAVT
ARPLARSSRESRLSPLAFLSVSASQNAVQTTPPFSGASEKTPLRVGSRASPLALAQARQF
VYRLALRFPDAFPQAHEIIQASLAKLSNPLPSSSSSDSSSASPSSSSSASSSSSSSPANS
HLASSAFSSVLASLLRVDSRLEYGELRIVPMQTTGDKELHLPLAQVGGKGLFTKELDLAL
LHGQVDVVVHSLKDVPTELPEGTEIGAYLPREDPRDALIFSRKPRRGLSRACKAQVPGGV
AETARRSATQQRVSAAASGAPSVGSSASASLLPYLPDALFASGGLPEETEEAGRAARASH
TEDDAGGVEGEARKADEGRPRIGTCSLRRQALLYALLPPSSFQLMGLRGNVQTRMSRIEK
GTLDATLLAAAGLKRLNLLSAMLAPSPSATPSPCPASSPNEASRGTEPGGCVEAVLLPAD
VFVPAVCQGIIGVQCRSADTGILSLLRELNSPSSRGQALCERAFLRALDGSCRTPIAGIA
EWRAVPAQGEAPRPQSQNGSDEPGVEREGEEGCAGSSVERREGRSEEGWGGHPDCFTEKT
ELRFCGVLATPDGKQLFREERTVRGVRTPEEAEALGRAVAEEIKKAAGADRLAQIKKHVT
EGWKNLKTL
>D0KW74|hydroxymethylbilane synthase|EC 2.5.1.61|Halothiobacillus neapolitanus (strain ATCC 23641 / c2)|TrEMBL
MTPTAPSVDLIRIATRESPLAMWQTEFVADELRRLHPGLRVELVSMTTKGDQLLDSPLAK
IGGKGLFVKELELALMDGRADIAVHSMKDVPMRFPDGLELIAILEGHDPRDAFVSNEYES
LAALPAGAVVGTSSLRRETQIRSRYPQLEIKMLRGNIQSRMAKLDRGDYDAIILAAAGLK
RMGYDARIRAELSPEESLPSVGQGALGIEARSDDAAIHALIAPLIHAATTTRVLAERAFN
TRLNGGCQVPIGGYAMLQDDGNLWLRGMVGRPDGTLTLRDEITGAATEGEALGVALAERM
LAAGADKILAEVGIHADPA
>G0AJM7|hydroxymethylbilane synthase|EC 2.5.1.61|Collimonas fungivorans (strain Ter331)|TrEMBL
MSKISPPSKLVIASRESPLAMWQAEHVRERLSALYPDCNIEILGMTTRGDQILDRTLSKV
GGKGLFVKELEVAMAEGRADLAVHSLKDMPMELPPGFVLSAVLEREDPRDAFVSNDYASL
EQLPAGAIVGTSSLRRQALIAARFPLLQIKPLRGNLGTRLAKLDRGEYAAIILAAAGLKR
LGLADRITAPIEPEQSLPAPGQGAMAIEIRADRADLQEILAPLNHLPTELAVTAERTLSR
AFGGSCQVPLAAFATIDGDQMRLRAMIATPDGLRVAVADASGAADAPEVLGETIAAALEA
QDAGAILALCKEA
>G0FL15|hydroxymethylbilane synthase|EC 2.5.1.61|Amycolatopsis mediterranei S699|TrEMBL
MGTRGSKLALTQTGTVADALRATGVEVEIVKVTTPGDKSLAPIATIGVGVFTSALREALL
RNEVDVIVHSYKDLPTAPEPGITLAAVPPREDPRDALIARDGLTLGELPPGSTVGTGAAR
RTAQLRALGLGLEIVPIRGNIDTRMRKVTDGELDAVVLARAGLARVGLVEAITETLDPIQ
MLPAPAQGALAVECRSADVDLEHLLRSTLDDEGTRAAVTAERALLAALEAGCSAPVGALA
EIVEDLDAEGKVVERISLRGTAAIEGEEGAVDMVRAIALADKDQAAQLGKDLAAELLDLG
AGALSGPAQ
>G0FL15|hydroxymethylbilane synthase|EC 2.5.1.61|Amycolatopsis mediterranei S699|TrEMBL
MGTRGSKLALTQTGTVADALRATGVEVEIVKVTTPGDKSLAPIATIGVGVFTSALREALL
RNEVDVIVHSYKDLPTAPEPGITLAAVPPREDPRDALIARDGLTLGELPPGSTVGTGAAR
RTAQLRALGLGLEIVPIRGNIDTRMRKVTDGELDAVVLARAGLARVGLVEAITETLDPIQ
MLPAPAQGALAVECRSADVDLEHLLRSTLDDEGTRAAVTAERALLAALEAGCSAPVGALA
EIVEDLDAEGKVVERISLRGTAAIEGEEGAVDMVRAIALADKDQAAQLGKDLAAELLDLG
AGALSGPAQ
>I0GTK3|hydroxymethylbilane synthase|EC 2.5.1.61|Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421)|TrEMBL
MKNTIVIGTRSSKLALWQAEYVKGRLEEEYPGLTVELKLMTTKGDKILDAPLAKIGGKGL
FTKELEMDMLDGGIDLAVHSLKDMPTELPAGLCLAAITKRFDPGDAVVSPKFKTFDALPC
GAKVGTSSLRRKAQLLHARPDLNICDLRGNVNTRLAKLESENFDAIILAVAGLKRLGFGE
RITEVLPQEMVLPAVGQGALAIETREDDAEMREMLAFLNDEATVHCAKAERAFLGRVEGG
CQVPVGVYAVPAEKEEIQVEAVIASLDGQRLYRDKISGKVEDAEKLGVTLAEKLLAAGGK
SILQELGLLQEAAN
>H7YLZ9|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 86605|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>B3IH12|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli E110019|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPT
>H7FNC2|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacterium frigoris PS1|TrEMBL
MAEKTIKIGTRDSELALWQAHTVEKKLNDLGYKTEIIAVKSTGDIILDKPLYELGITGIF
TKTLDVAMINGDVDIAVHSMKDVPTVLPIGIVQAAVLERASTLDILVHKGNLDFLNESGT
IASGSLRRQAQWLNKYPSHKVVDLRGNVNLRMKKLNEGDWNGAVFAAAGLERINLKPENF
INLDWMIPAPAQGAMVVVAMQNDAFTRDALSQLNDIETEIVTYIERQFLKTLEGGCTAPI
GALAIYNDDEDTIHFQGVLFSLDGKEKIEIDKIVPIEEWKKLGFYSAQEVLNNGGAKLMT
EIKNNLKK
>C6WZF5|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacteriaceae bacterium (strain 3519-10)|TrEMBL
MNSPITNSMRSIKIGTRNSPLALWQAREVARHLQNNNHTTDITPIISKGDKNLSQPLYTL
GITGIFTKDLDIALLNNEVDIAVHSLKDIPTQLPENVEIIAVLQRDYPQDVLVRKKDAAT
LELHQLKIATSSLRRRAFWLKEFPGTEFSDIRGNVQTRLTKLEENDFDATMFSLAAIERM
GLSVDYEHLPLMIPAPAQGVVAVCARSNDPEIKELFKEINHRETRICIDIERSFLSTLEG
GCTAPIGAFAEINDLGEVRFTGRICSLDGQNCIETDEIFAWNEHDDFGKILAEKILQNGG
RELMQEIKSKL
>Q2G4K1|hydroxymethylbilane synthase|EC 2.5.1.61|Novosphingobium aromaticivorans (strain DSM 12444)|TrEMBL
MNNQAPQRPLKLGTRRSPLAMAQAEEARARLCAAHGWAESQVELVPVTASGDKIQDRPLA
DIGGKALWTKELDAWLVSGEIDFAVHSMKDVETIRPENFAIAAVLPRADVRDVLIGAASI
HAIPPGARVGTSAPRRAAQMLHARPDLTVVSFRGNVATRLAKLQAGEADVTLLAAAGLGR
LGETGVGHPLSEYEWLPAPAQGAIGIECLASRADLCAWLGAIDDKPTHHAIRAERALLLA
LGGNCHSPIAVLTTHHESSLTLRAALFSPDGAERVEAHETFAAGDDAGPAHLAHRLLGEA
PDAIRVHFHGAG
>H6LWN1|hydroxymethylbilane synthase|EC 2.5.1.61|Francisella tularensis subsp. tularensis TIGB03|TrEMBL
MKQITIASRESKLALWQTNFVKNRIQLELNIPCEISTMKTQGDIILDQPLNKIGGKALFM
KELEVAMLSNKADIAVHSLKDVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGA
VVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGDYDAIILASAGLIRLELVERI
TQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES
>Q3KM63|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>H0AV19|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21202|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSELPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGADPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>F8A7R2|hydroxymethylbilane synthase|EC 2.5.1.61|Cellvibrio gilvus (strain ATCC 13127 / NRRL B-14078)|TrEMBL
MSAVRIGTRASTLALTQTGHVADDLARLGGLTTELVHVRTDGDRLTGSLASLGGTGVFVT
TLRDALLDGRCDVAVHSLKDLPTTPAPGLTIAAVPVRQDPRDALCARDGLTLRELPPGAL
VGTGSPRRAAQLLAARPDLVVVDIRGNVDTRLGRVAGAEHGPGDLDAVVLARAGLARLDR
LDAVTEALDPATMLPAPGQGALAVEVRTADLADPTHPLAAALAALDHTPTRLAVVAERAL
LARLEAGCAAPVGALARVEGATIDLSAVVARTDGTQTLRHGLTVTRRVAWEQADEPPSAA
EAAVLTAVDEATARAAGTDLADLLLELGAADLAPLGPAA
>D3UJ40|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198)|TrEMBL
MSKQNRQIIIGTRGSALALWQAEYIAMRLKKELGIESRLQIVKTQGDRMLDVPLAKIGGK
GLFTKELEKLLLQEKIDIAVHSLKDVPVEFVEGLDLACITKREDVRDCFLSVRYASILDL
PPGARVGTTSLRRSMQLKILRKDLDTQSLRGNVQTRLKRLFDGEFDAIILAQAGLNRLGI
DQQKVPFLKPFSTEELIPAMGQGALGIEAREGDGIFSLLQGLNDEATAICTNAERTFIRV
LDGGCQVPIGVHAQCNNQDFVIHAILGLPDGSKVLRDSISGSTKDSILLAENLAERFLSQ
GALEILEQAKEMAFL
>C5WB39|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli (strain B / BL21-DE3)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDNLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>A3GZL4|hydroxymethylbilane synthase|EC 2.5.1.61|Vibrio cholerae B33|TrEMBL
MDRNIIMTETPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLA
KVGGKGLFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYA
KIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGL
KRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAM
NLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQL
LSQGAKEILERLYCDHE
>E6MVN7|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup B / serotype 15 (strain H44/76)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLD
GRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>E4U289|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfuricurvum kujiense (strain ATCC BAA-921 / DSM 16994 / JCM 11577 / YK-1)|TrEMBL
MKKLTIATRGSKLALWQSNHIKSVIESQFSDVEVELKIIITSGDKILDVPLAKIGGKGLF
LKEIEESMLRGEAQMAVHSLKDVPTVMPQGLLLSAITVREDVRDAMLSEKYPDIKSLPQG
AVVGTSSLRRRMQLVQQRPDLVIKDLRGNVDTRIRKLKEGEFDAIILAAAGINRLGFSNL
VQYFYPIALDEMLPAMGQGALGIETVNEPWVLEIAKFLEDENSRIETTIERGFVDTLQGG
CQVPIGVSARVQPNGEVIVRSTLGMPDGSEVMGDEVVVAKGQTEGVGEAMAKRLIAQGAM
ELLHRAETMANKG
>E7AAI6|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1)|TrEMBL
MGAKLVIGSRGSALALWQARHVQELLKPLGLESEIKIVKTKGDKILDVPLAKIGGKGLFT
KELEVLLLGGKIDLAVHSLKDVPVDLQEGLVLACVSARANPQDCFLSYKYPNLQALPPNA
RIGTTSLRRAMQLKALRTDTDPLSLRGNVQRRLERLQRGDFEAIILACAGVERLGLELPY
RVPLSLEEMIPSMGQGALGIEMRANHPLLDQITSLNDPNSALCCGLERDFVRALGGGCQV
PLGVHARLQGEHIEMRAIVGLVDGKTFIKERASAPRDRAQELAHNLAHTFKQKGALEILA
QAQMH
>G8TWD8|hydroxymethylbilane synthase|EC 2.5.1.61|Sulfobacillus acidophilus DSM 10332|TrEMBL
MANLSIGTRGSELAVRQTDLIVSRLESQEHHVTVVRVETHGDRVLDRALNQLGNQGVFTT
ELEQRLVAGTIDLAVHSLKDLPTQLAPGLAIGAYALPEDRRDVLLAGDYTLATLPPGARV
GTSSLRRTAFLRSLRPDLEVVPVRGNLQTRLRKWQELGLDGLLLAAAGVHRLGWQDKISE
YLDPFAMVPAPGQGILAVEMVADRQDIAKILAPLDDPAARVLAQAERGVLARLGGGCQMP
LGAYATWDGETVYLLGQAADPAGTRLARAEARGTASDTDRLAEEVADELRRQGALAWIQP
>D5D580|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O18:K1:H7 (strain IHE3034 / ExPEC)|TrEMBL
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPL
AKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICKREDPRDAFVSNTY
DSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAG
LKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERA
MNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEE
LLNNGAREILAEVYNGDAPA
>E7YT61|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 19N|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>B0GUK1|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis biovar Orientalis str. MG05-1020|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>G4R6U9|hydroxymethylbilane synthase|EC 2.5.1.61|Pelagibacterium halotolerans (strain JCM 15775 / CGMCC 1.7692 / B2)|TrEMBL
MTSTPVLTIGTRGSPLALRQAEEVRDRLVAINGLEPDTIAIKIIKTSGDIILDRPLSEVG
GKGLFTKEIEKALAESEIDIAVHSAKDVATEIDPLFALPAFLPREDVRDAFLSLIAKSPD
HLPEGAVIGSSSLRRRAQMKRFRPDFRTVEFRGNVQTRLKKLADGVADATLLAMAGLNRL
GEAHRVTHTLDVAHFPPAPAQGAIVIETRADDGAANRLVEVLDDPDTRKRVEAERAFLKV
LDGSCRTPIAALTTLDGDNLTLFGQILSPDGSEVYEDETSGDADRGRDLGTRLGEKLLAA
AGPDFIERLKQGQYG
>H6PZ52|hydroxymethylbilane synthase|EC 2.5.1.61|Rickettsia rickettsii str. Hino|TrEMBL
MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKAL
FLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQ
NAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEVFN
PEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSQYLDANPRHLSKLAYREVFEGNTEALATAAYKSNRTDASTGLTYKLPLEV
EFGKMSNIQTNFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
>H8AQF8|hydroxymethylbilane synthase|EC 2.5.1.61|Campylobacter jejuni subsp. jejuni 1997-10|TrEMBL
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTK
ELEESILRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAK
IGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVN
FVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELL
KKAESMI
>B4W913|hydroxymethylbilane synthase|EC 2.5.1.61|Brevundimonas sp. BAL3|TrEMBL
MNLPLRIGTRRSKLALAQSGMMQRAIGRALGVAEAEIEAAVPLVEIVTTGDRIQDRRLME
MGGKALFTKEIEEALLDRRIDIAIHSMKDVPAEQPEGLCIAAIPEREDARDAFISRDFDS
FDQLPFGARLGTASLRRQAQALALRPDLKVEMLRGNIDTRLRRAAEGDFDAILLAVSGMT
RLGVTEHIREKLSLDAFLPAPGQGALAIQTRADDIDAPWVAALNHPETAVAVAAERGAMT
ALEGSCRTAVGAYALIEGDTLRLTTEMLSPDGSARWRRVGELFQPTEADARALGERLGGE
VHAFAGDQEVDPASLDG
>B7KAK5|hydroxymethylbilane synthase|EC 2.5.1.61|Cyanothece sp. (strain PCC 7424)|TrEMBL
MAVSSPTRTVRIGSRKSQLALVQTYWVQEQLQKHHPDRQFEVETMSTQGDKILDVALAKI
GDKGLFTKELEVSMLEGQTDLAVHSLKDLPTKLPDGLMLGCITERVDPADGLVVNEKHKD
KQIETLPEGAVIGTSSLRRLAQLRYHFPHLTFKDVRGNVNTRLAKLDAGEYDAIILAVAG
LTRLGMSDRIHQVIPSDISLHAVGQGALGIECRTEDPEILELLKVLEHQPTRDRCYAERS
FLRELEGGCQVPIGVNTSVDGDTLTLTGMVASLDGKKLIKDTITGKTTDAEQLGKDLAIR
VRNAGAGEILAEIFAQIERG
>I6IC20|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis PY-34|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>D6YD58|hydroxymethylbilane synthase|EC 2.5.1.61|Chlamydia trachomatis serovar E (strain E/150)|TrEMBL
MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQG
DLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVISITASIDPRDI
LVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAI
VMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCF
S
>D5S158|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium difficile NAP07|TrEMBL
MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDLIQNVSLDKIGDKGLFV
KEIEQQLLYGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPRDVLILREGYKNLDDLPRG
AVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDENMHGIVLAASGIIRANLQDK
ISSYLPVDVVIPAPAQGALAIEIRSNDSKIEGIVNSLKDENTEIQILAERGFLDGVNGSC
HIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDGDISSPRELGLKLAKLVLKEYENYE
G
>E7ZUD1|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 366867|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H0M752|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035320|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>B8GJJ1|hydroxymethylbilane synthase|EC 2.5.1.61|Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)|TrEMBL
MSIRVGTRGSALARVQTEKVCSMLASRGIETETVVITTHGDAVTGVPLHEIGGQGVFVRA
LDDAIEAQEIDCAVHSLKDVPALRPPGVLTCAVLKRNSPADFLAVDAVENPQIIGSSSTR
RRAQLLRHDPSLEVKQLRGNVDTRIRKLKAGEYDGIVLAEAGLQRLGLSLKGKRLPVDEF
VPSPNQGTVAVVCREDPSLIETLACALDHEGTRQDVVFERAVMEELGGGCFVPEGVYCRD
GHLIAEVLALDGSRYQRIEADPSDVREAREIGRRLKVQAADLISDAVRTLGLEE
>A4MG08|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia pseudomallei 305|TrEMBL
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRT
LSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSND
YASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAA
GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRR
VSDALERQGARAIVDAFVAASAQAQKGGA
>B5YJZ4|hydroxymethylbilane synthase|EC 2.5.1.61|Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)|TrEMBL
MTVKRNKIVIGSRGSKLAMWQANWVKDKLQTLYPELKVEIEKIKTTGDKILDAPLAKIGG
KGLFVKEIEEALLSKRVDLAVHSMKDVPTEIPEGLQISAICEREDPRDAFISKDGVLLNE
LPQEAVLGTSSLRRTVQLKALRNDLVIKPLRGNVDTRIRKLKDGEFQAIVLAMAGVKRMG
VENLVTQAFSEDLMIPAIGQGAIGIETRVDDDFVNELIKPLNHEETAICILAERAFLSVM
GGGCQVPLACHARIVNNSLKIVGMIGDPEGKMPVIKGFREGSLSQAQSLGVELANELLHR
GGKEILEKVYK
>A6FTT5|hydroxymethylbilane synthase|EC 2.5.1.61|Roseobacter sp. AzwK-3b|TrEMBL
MTLSVDIRHAFGDFTLDVSFEAPPGLTVLFGRSGSGKSTVINAVAGLLSPDTGRITVEGK
TLFDRTQGIDLAPHRRGLGYVFQEGQLFPHMTVRQNLMFSRWFRKGARSDFHEVVEMLGI
GALLDRRPLALSGGEKQRVAIGRALLGDPRIILADEPLAALDEPRKAEILPYFERLRDEI
SVPILYVSHSATEVARLATTVVTLENGQVTGQGPATGILGDPMLTPLGARAAGAVLETKV
ARHHDDGLTELSAGGVALFVPRVAQAAGQPLRIRIAAQEVILSRTRPEGLSALNILPGQI
TTIRSGAGPGALVSVATPAGILLARITQRSARLLDLTEGASCYAIVKSVAIAPEDVGGSD
RVPKAL
>B2PK56|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O157:H7 str. EC4076|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>D2RNT2|hydroxymethylbilane synthase|EC 2.5.1.61|Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / VR4)|TrEMBL
MKKLIVATRGSRLALAQTHIVCRLLEEAGVETEIRTITTAGDRDRIHALVKIGGRGIFVR
EIERELLSGEADIAVHSAKDLPYQLASGLVIAGTPSQADPRDALVLLKERKLEAGSVVGT
GSPRRIREISRVLPELVFRDIRGNVTTRLHKLERGEYDAIVLAMAGIQRLALDMEQFQIR
PLSTEQVIPAGCQGIIGVECRQKDRELVRLLQQISDPETWRRFQWERQLFTSMKVDCSRP
VGIHCRLLKSGRMELLAMVDGKRARRLGMEKEGKALCASLKEELYDRK
>H6ME83|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O55:H7 str. RM12579|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPHGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D5HFP9|hydroxymethylbilane synthase|EC 2.5.1.61|Coprococcus sp. ART55/1|TrEMBL
MRVENGHGKNKPNIRKLAENDMADGFNSDGLDFESGGQKKTVKVGTRSSKLALAQTELVI
KALNERFPQVDFQMVTMSTRGDRDTSRALLEFGGKAVFVEEFEEAIFKGDIDIAVHSAKD
MPMEIMEGLTISGTLPRACPQDILIYKSGRIFDRNDSFVVGTSSLRRQYQIRDMYRNAEC
KNLRGNVGTRIQKLEDGEYDAIILAAAGLERLGVIEDKGNDSTECFEVHKDELTFRYIST
ESMLPAACQGIIAIETRTSGEVYDMVRAINDTEAYTQLTCERAVLSRLNAGCHEPIGVYS
ELHGDHMKLSLMKADAASSDKEKDEEIQIHRKTVEGNTAEWEQLVENLIK
>Q5FHN5|hydroxymethylbilane synthase|EC 2.5.1.61|Ehrlichia ruminantium (strain Gardel)|TrEMBL
MNSMNVYLGTRGSILAIAQAMKVKKLLYNYFPDINVQIVHIVTSGDINDKISLSEIGGKG
LFLKELEEALLTGTIDLAVHSMKDVPAFYCDSLVIPCILKRSSPYDVFISSKYQSLRSLP
DNAVIGTSSIRRKVQLMRLLSSVQVVPIRGNVDTRILKLEAGQYDGIILAKAGLMRINKT
HVIKEVLDPQVMLSAVGQGAIGIQCRANDYKMIDMIKILNCKKSYISVAAERSFMKTVNG
SCDTPLAALAKYVNSDTLYMSCMLSNEEKTVFSDCYFNECDAEISGINMGNDLMDQLNN
>H8WDN0|hydroxymethylbilane synthase|EC 2.5.1.61|Marinobacter hydrocarbonoclasticus ATCC 49840|TrEMBL
MSDMSKRTLRIATRSSALALWQAEFIKAELERLHDNVDVELIKIKTQGDKILDVPLAKIG
GKGLFVKELEEAMLDGRADLAVHSMKDVPMEFPEGLGLVAICEREDPTDAFVSNQYEHID
QLPEGAVVGTASLRREAQLRANRPDLQIKVLRGNVNTRLAKLDAGEYDAIVLASSGLKRL
GFHDRIRYCLPDTFSLPAVGQGALGIECRVGDTELLELIAPLNHTDTWDRVSAERALNRR
LEGGCQVPIAAYALLEDDNTLWLRGLVGAVDGTQIFRVEGRAPRAEGERLGRELAEQLLS
MGADKVLAEIYGHTPR
>A6W1B4|hydroxymethylbilane synthase|EC 2.5.1.61|Marinomonas sp. (strain MWYL1)|TrEMBL
MRKSERYLSIYKSLGDEVKDKIVIATRESQLALWQANNIKAQLESLYPDMKVELLGMTTK
GDQILDSPLSKIGGKGLFVKELENALTEGLADIAVHSMKDVPMAFPEGLGLAVICEREDP
HDAFVSNKVESLDQLPSGAIVGTSSLRRSCQLRMKRPDLIIKDLRGNVNTRLKKMDDGEY
DAIILATAGLVRLEMLDRIRQRIPAETSLPAGGQGAMGIECRSDDIQTINLLAPLQHEET
AIRVTAERAVNERLNGGCQAPIACFAILENDTLWLRGLVGSPDGKTMIEGEIRGHKDDAK
SLGVQLADDLLARGADIILNALYNEE
>D9R7W0|hydroxymethylbilane synthase|EC 2.5.1.61|Clostridium saccharolyticum (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1)|TrEMBL
MKSKTIRIGTRRSALAVAQANIMAEALERTGTGLSAELVLKLTEGDRILDKPLLEFGGKG
VFVTEFEQALLRGEIDFAVHSAKDLPMELEEGLGIVAVLEREDPRDVLVTPASGILSGKR
EIIIGTSSLRRKIQIEEIGKTMWPEALVRCENLRGNVLTRLSKLMEGSYDGIILAAAGLK
RLGLWEDSRYHYHCFDCDTFIPAGGQGILAVEGRLDSGLEAVVKSLEDEEARLCLTMERK
ILKLLNAGCHEPIGVYSRLKNGEIEILGISRRGEEAKRIHLRGGIGELDRLALLAAESLG
>C4WC32|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus warneri L37603|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKQVRPDLDIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQNELFEKQIDMAIHSLKDVPSVIPEGLTLGCIPDREVPFDAYISKNHTPLRELPEG
SIIGTSSLRRGAQILSKYPHLEIKWIRGNIDTRLQKLETEDYDAIILAAAGLRRMGWSDD
IVTTYLDKDILLPAIGQGALGIECRSDDEELLELLKEVHNKDVEKCVTAERTFLAEMDGS
CQVPIGGYATINSQQQIEFTGLIMTPDGTERYEHTAIGESPTELGKEVSRVLKEQGAYEI
IRKLNEEQ
>F7T495|hydroxymethylbilane synthase|EC 2.5.1.61|Achromobacter xylosoxidans AXX-A|TrEMBL
MVIATRASRLALWQAEHVRDRLRTLYPACAVELLTLTTRGDQILDRTLSKVGGKGLFVKE
LENALLDGRADLAVHCLKDMPVDLQAPFELCAVLDRADPRDAFVSNRYDTLADLPAGAVV
GTSSLRRESQIRARYPQLVVKPLRGNLDTRLGKLDRGEYDAIVLAAAGLNRLGLTDRIRC
LLDPADCLPAAGQGALTIEIRDDRDDMRAWLAPLNDATATSISLAERAVSRRLGGSCQVP
LAAYAEIDGGKLTLRALVASPDGTRTLRAERSGPVDQAQAIGEAVAAELFDAGAQAILDE
LLQDASPED
>F0B660|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis M01-240013|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESESLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>F3G2C6|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas syringae pv. pisi str. 1704B|TrEMBL
AGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNGGCQVPIACYAVLEG
DDVWLRGLVGDPSGSVLLHADARAPQTSAQALGVQVAEALLEQGAADILKAVYGEANNE
>H8XNL9|hydroxymethylbilane synthase|EC 2.5.1.61|Flavobacterium indicum (strain DSM 17447 / CIP 109464 / GPTSA100-9)|TrEMBL
MKNKTIRIGTRDSELALWQAHTVEKKLNDLGYKTEIVAVKSQGDIILDKPLYELGITGIF
TKTLDIAMITGQVDIAVHSMKDVPTALPQGIVQAAVLERANTVDLLVHKGNLDFLEKEGT
IATGSLRRQAQWLHKYPQHQTVDLRGNVNTRMQKLQESDWGGAIFAAAGLERINLKPDTF
INLDWMIPAPAQGAMVVVAMAEDTFSLEALSELNHVETEICTYIERQFLRTLEGGCTAPI
GALATYEEKTDELHFQGALFSIDGKQKLAIDRKYDISEWKKLGFNAAKEILANGGKEVME
TIKLQLKK
>A3Y6B3|hydroxymethylbilane synthase|EC 2.5.1.61|Marinomonas sp. MED121|TrEMBL
MKDKIIIATRESQLALWQANNVKDSLAALYPDIQVELLGMTTKGDQILNSPLSKIGGKGL
FVKELEHALLDGRADIAVHSMKDVPMAFPEGLGLAVICEREDPTDAFVSNKYDNLASLPQ
GAVVGTSSLRRSSQLALARPDLVIKDLRGNVNTRLRKLDNQEYDAIILATAGLMRLEMTD
RIKERISDQDSLPAGGQGAMGIECRSDDADMIKLLAPLQHQETYYRVTAERAVNERLNGG
CQAPIAAFSLLEGDELYLRGLVGSVDGSTILRDEIRGSKNDAHALGVQLAEKLIAAGADT
LLAEINKD
>D3FWC2|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus pseudofirmus (strain OF4)|TrEMBL
MRTIVIGSRRSNLALTQTDWVINQLKKKEVPYNFEVKKIVTKGDRILDVTLSKVGGKGLF
VKEIEQALENKEIDIAVHSMKDVPSVMPEGFSLAAITEREDARDAFISLDHVKLKDLPSG
AIVGTSSLRRSAQLLAERPDLEVKWIRGNVETRLRKLKEEDFSAIILAAAGLNRLGYSEE
LVTEYLEPEMCVPAVGQGALGLECRSDDQEVIELIQKLNDEATALTVTAERTFLHKMEGG
CQVPIAGYATMQEDGQVSLTALVGSPDGKTILKDTVVGQDPVKVGEEVSERLLEKGAKEI
LDKVKRELDA
>H0D309|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21232|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>G8U9E0|hydroxymethylbilane synthase|EC 2.5.1.61|Bacillus cereus F837/76|TrEMBL
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLF
VKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEG
AILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNE
VITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTDPEKVGLEAADRLIKQGAKEL
ILAANKGQQ
>Q3J029|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)|TrEMBL
MTHSMPTPAEPLKIGTRGSPLALAQAYETRSRLSAAFSLPEEAFEIVVIKTTGDKVLDRP
LKEIGGKGLFTREIEEALLSGGIDIAVHSMKDMPTLQPEGLILDTYLPREDTRDAFITFA
EGGLADLPQGATVGSSSLRRRAQLLNKRPDLQVVEFRGNLQTRLKKLNDGVARGTFLAMA
GLNRLKMNEVPRVPIESEEMLSAVAQGAIGIERRTDDPRAQEMLAAIHDVPTGHRLAAER
SFLLKLDGSCETPIAGLAILEGDQLWLRGEILRPDGSESISGEIRGAIADAAALGSELAS
ELLGRAPADFFSWR
>D8JHV7|hydroxymethylbilane synthase|EC 2.5.1.61|Acinetobacter sp. (strain JCM 1667 / KCTC 23045 / DR1)|TrEMBL
MLEFMKTLKIATRQSPLALWQAEHIRARLQELHPDLTVELVKFVTQGDKILDTPLAKIGG
KGLFVKELEAALLDGRADLAVHSMKDVPMALPEGLSLAVICEREDPLDAFVSNQFEKFAD
LPQGAKVGTSSLRRKSQILKQRPDLQIIDLRGNVGTRLAKLDDGQYDAIILASAGLKRLG
LSERIRHCLTPDISLPAVGQGALGLECRAADQDVLALIQPLLHEETDVCVRAERAFNAYL
EGGCQVPIAGYATLQNGQIHIEGRVGSPDGQTLLRAELTDEASNAHQLGENLARNLLDQG
AGELLKALY
>E1Q264|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain SJM180)|TrEMBL
MEKLVIGSRGSELALWQANYIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLQRLNVQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEEFLQSGAKEIL
EKAQLF
>Q28KK0|hydroxymethylbilane synthase|EC 2.5.1.61|Jannaschia sp. (strain CCS1)|TrEMBL
MTTNLPTPAAPLRIGTRGSPLALAQARETRARLMAAWDLPEDAFEIVVIKTTGDDRSLID
ADVALKELGGKGLFTKEIEEDMLTSSIDIAVHSMKDMPTVQPDGLMLDCYLPREDVRDAF
VSVNHDGLHALPEGAIVGSSSLRRRAQLFARRPDLNVVEFRGNVQTRMKKLGGGVADATF
LAMAGLRRLGMEEVVKSAIEVEDMLPAVAQGAIGIERRVSDTRAGDMLAAIHNTETGQRL
AAERSFLKGLDGSCQTPIAALAELDGGTLRLRGEILRPDGSEVLTDDRTAPIEDGAALGA
DMARDLRARAGDGFFDWH
>E8TJV6|hydroxymethylbilane synthase|EC 2.5.1.61|Mesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)|TrEMBL
MQTILRIGTRGSPLALAQAHETQARLMAAHGMPAEAFEVVVISTSGDRIQDRPLSEAGGK
GLFTKEIEEALLAGRIDIAVHSSKDMPTQLPDGLELSAFLPREDARDAFVGKVAKAIAEL
PRGAKVGSSSLRRQALIRRMRPDLDVVMFRGNVQTRLRKLEEGVAAGTILAYAGLKRLGL
EHVVTDLIPLDVFPPAPGQGAIGIETRIGDRDVEKMLAAVHDVPTGQALACERAFLAALD
GSCRTPIAGYAAIEAGKLSFAGLIISPDGTQSHTVELQGSAQDAARIGGEAARSVRARAG
EKFFDGWL
>G8RV47|hydroxymethylbilane synthase|EC 2.5.1.61|Mycobacterium rhodesiae (strain NBB3)|TrEMBL
MTVIRIGTRGSLLATTQAGVIKKELESRGHPAELVIIATEGDRSDAPVADIGIGVFTAAL
REAIHDGRVDMAVHSYKDLPTASDERFTIAAIPPREDARDALVARDGLVLGELPAGSTIG
TSSPRRAAQLRALGLGLEIRPLRGNLDTRLNRVSNGDLDGIVVARAGLARIGRLADVTET
LEPVQMLPAPAQGALAVECRAGDAELAALLSELDDADTRAAVTAERALLAALEAGCSAPV
GAIAEVVESIDEDGHVFEEVSLRGCVATLDGSDVIRASGVGRTDRARELGLSVADELFEL
GARELMAETHEEHRGE
>H5NWW0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC14C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>B0H947|hydroxymethylbilane synthase|EC 2.5.1.61|Yersinia pestis biovar Mediaevalis str. K1973002|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKG
LFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLP
AGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLE
NRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAR
EILAAVYLDNPAR
>H3RIV8|hydroxymethylbilane synthase|EC 2.5.1.61|Pantoea stewartii subsp. stewartii DC283|TrEMBL
MLNKIFRIATRQSPLAMWQAQYVQQRLMSAHPGLQVELVPMVTKGDIILDTPLAKVGGKG
LFVKELEQAMLENRADLAVHSMKDVPVAFPAGLGLVTICQRDDPRDAFVSNHYASIDELP
HGAVIGTSSLRRQCQISARRPDLVIRSLRGNVGTRLSKLDAGDYDAIILAAAGLNRLGLE
ARIRQLLPAEISLPAVGQGAVGIECRLDDSTLIGLLQALNHDDTAVCVKAERAMNTRLEG
GCQVPIGSFAVLNGDEIWLRGLVGAPDGSTVVSGERRGPRSQAEQMGISLAEELLNNGAR
EILHDVYQGQPPV
>E8QE80|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori (strain India7)|TrEMBL
MGKLVIGSRGSELALWQANHIQERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGAIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKRGDKTKAFDLIQELLEEFLQSGAKEIL
EKAQLF
>D5CLC1|hydroxymethylbilane synthase|EC 2.5.1.61|Sideroxydans lithotrophicus (strain ES-1)|TrEMBL
MSQASLIPPARLVIASRESALAMWQAEHIRDRLRALYPQTSVSILGMTTQGDQILDVTLS
KIGGKGLFVKELETALENGSADIAVHSLKDVPMNLPEGFALACIGEREDPRDAFVSNRFD
NLAALPAGSVVGTSSLRRESQLRARFPHLKIEPLRGNVQTRLRKLDEGQYAAIILAAAGL
KRLGLGERIRAVISSDESLPAVGQGALGIETRADRPDLKAVLAPLHHADTAACVLAERAM
SRALAGSCQVPLGGFAEVQNGKLRMRGFVATPDGTRLLRAEHVGDIAQPEALGDLVAQDL
LRQGAGEILAALNG
>D1RXX6|hydroxymethylbilane synthase|EC 2.5.1.61|Serratia odorifera 4Rx13|TrEMBL
MLDKIIRIATRQSPLALWQAHYVQQRLMASHPGLQVELVPMVTKGDIILDTPLAKVGGKG
LFVKELELALLEGRADIAVHSMKDVPIDFPAGLGLVTICERDDPRDAFVSNRFASFDQLP
QGSVVGTSSLRRQSQLRERRPDLIVRDLRGNVGTRLAKLDNGDYDAIILAVAGLKRLGLE
QRIRSPLSPEECLPAVGQGAVGIECRLDDDATRALLAPLNHAATDIRVRAERAMNTRLEG
GCQVPIGSYAELEGDSLWLRALVGSPDGSQMVRGERRGPAALAEQMGVELAEELLARGAR
EILHDVYQGNPPA
>D8JZJ2|hydroxymethylbilane synthase|EC 2.5.1.61|Dehalogenimonas lykanthroporepellens (strain ATCC BAA-1523 / JCM 15061 / BL-DC-9)|TrEMBL
MRKIRLGSRSSRLALAQAEYLQARLRAAFPEVEFDIVRISTQGDRNRLVSMGELPGVGFF
VKEIESALAAGEADIAVHSLKDVPVELPPEFILAAVPEREDTRDVLISRGRKLDQLPVGA
VVGSDSLRRSFQIRARRPDVEVRSIRGNIETRIKAVEEGRVDAVILAAAGLHRLGLETRI
DEYLPLTEFLPPPGQAALGIEVRKNDDFSRETAGAVNHPPTCLAVTAERSFLRRLGGGCR
APIAALGTVEGDVLTLRGMVADEAGRNIISRSLSGTASAAEAVGGALAEMILEAGANKYI
N
>B8CA57|hydroxymethylbilane synthase|EC 2.5.1.61|Thalassiosira pseudonana|TrEMBL
MAEEGAVTPLRIGTRGSPLALAQAYETRRRLIENFPELEAEGAIEICVMKTQGDMILDKS
LMELGGKGLFTKELDTALLGDEVDICVHSMKDVPTWLPEGTVLPCNLPREDTNDAFITAN
GDIKRIADLPDNSVIGTASLRRQAQILAQNPTLKCVNFRGNVQTRLRKLDDGVVDATLLA
IAGLKRMDMDDCATAILEWDEMLPAVAQGAIGIQCRSDDTRSLKYIDALNCMDTHVCVNC
ERAFLEALDGNCKTPIAGQARIVDGKIVFKGLIAMPDGSLKYETEATGEIADAVEIGRKA
GEELKAQAGEKFFEMMVEMSPQQVLGQITK
>D9TPE8|hydroxymethylbilane synthase|EC 2.5.1.61|Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814)|TrEMBL
MKKIRVGTRSSELALTQTLIVINEIKKYKPNIEFEIVKISTKGDSVLNAPLSEIGGKGLF
VKEIEDALINNEIDMAVHSMKDMPYEVPNDLKLLSVYRREDPRDVFISRSEKFIDLKNNA
RIGTSSLRRSVQLKNLRPDIEIVPIRGNIATRIKKMHELNLDGIVLAASGIKRLGLEDMI
KDYFPVDLIVPAPCQGILAVEIRRDFEEEFFEIYPMLLDAKTFFESSAERKIMKKFGGNC
KIPLGIYSEYKRNGNDDLITVRVSYYKDGKLIKGRETGLMRDIDKIGDRLVEKIGGI
>C4B0Y7|hydroxymethylbilane synthase|EC 2.5.1.61|Burkholderia mallei GB8 horse 4|TrEMBL
MTRQAMRRRTGPAGGCRMPSRTERPFGILTRTGRAVRAARPAGGRARCACYHSPFPIPPF
DVPAMNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQI
LDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAF
VSNDYASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAII
LAAAGLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAV
EAERAVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALA
LGRRVSDALERQGARAIVDALVAASAQAQKGGA
>Q2S2A6|hydroxymethylbilane synthase|EC 2.5.1.61|Salinibacter ruber (strain DSM 13855 / M31)|TrEMBL
MSISDPLVLGTRGSELALRQANVVRSRLEAAGHRVELETITTRGDEATDTPISEIGDEAV
FTKELDRALLQGGVDLAVHSLKDIPSTVPSGLALAAIGEREDPRDAFVAHPSFDGHLHDL
PEGATVATASLRRTAQLLTWRSDLEVVPVRGNVDTRLEKLGESDWTGMVLAVAGLVRLGL
SLHIRDRIDPSLIVPAVGQGALGIACREDQDALRDLLRETLHHAPSGHAANAERAFLKKV
GGGCQVPLGAWAHIDDGTLVLDACIAALDGSEHYRDERRCAPEDGAAVGRKLAADLLAMG
GDHILDDVLGESREGTSNSPFRP
>B6HRK2|hydroxymethylbilane synthase|EC 2.5.1.61|Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255)|TrEMBL
MVETSPTLPPLRIGTRRSNLAVVQAEGIRDSLKRIAPERSYEIETLRTLGDRDQLTALYD
FGAKSLWTTELEEKLVSGELDVIVHCLKDMPTTLPDTCELAAIPPRDDPRDALIVKSSLP
YTSIKELPKGAVVGTSSVRRSAQLRRLYPYLRFANIRGNVETRLAKLDNPASEYTCMVMS
AAGLERVGRKFRINQYLCSKDGGIFHAVGQGALGLEIRKGDTKTQELLDQLADRKSTLAC
LAERSLMRTLEGGCSVPIGVETEWIRSDVLKITALVVSLDGSESVEDSLEARVQTVDEAT
ELGKKIAARLVKAGAEAILKDININRPPKD
>Q6LER4|hydroxymethylbilane synthase|EC 2.5.1.61|Homo sapiens|TrEMBL
LARIQTDSVVATLKASY
>G2M7N5|hydroxymethylbilane synthase|EC 2.5.1.61|Helicobacter pylori Puno135|TrEMBL
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFT
KELEELLLKGEIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGA
KVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAK
YRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLERAFVKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEAFLQSGAKEIL
EKAQLF
>E3B6D1|hydroxymethylbilane synthase|EC 2.5.1.61|Dermacoccus sp. Ellin185|TrEMBL
MNSQAADAAPIRLGTRRSHLAMTQSTWVAEQLRAHGHAVEIVEITTEGDVNRASLAQMGG
TGVFAAAIRRALLEDEVDMAVHSLKDLPVAPEPGLVIAGIPVREDPRDALVARDGLTLGE
LPAGAVVGTGSPRRAAQLQALGLGFEIRDIRGNIDTRMGYVTSGELDGVILARAGLARVE
RTGAISETIDPLQMLPAPGQGALGLECREGDARVIAALAELDDADTRAAVTAERAVLGAL
EAGCAAPVGALAEIVEEPDGSLEISLRAFVGAPDGSFELRRSDVGSYDNPAAVGEALART
LLDDGAGAVIPPREAPNPTTSTKEAGA
>E3B6D1|hydroxymethylbilane synthase|EC 2.5.1.61|Dermacoccus sp. Ellin185|TrEMBL
MNSQAADAAPIRLGTRRSHLAMTQSTWVAEQLRAHGHAVEIVEITTEGDVNRASLAQMGG
TGVFAAAIRRALLEDEVDMAVHSLKDLPVAPEPGLVIAGIPVREDPRDALVARDGLTLGE
LPAGAVVGTGSPRRAAQLQALGLGFEIRDIRGNIDTRMGYVTSGELDGVILARAGLARVE
RTGAISETIDPLQMLPAPGQGALGLECREGDARVIAALAELDDADTRAAVTAERAVLGAL
EAGCAAPVGALAEIVEEPDGSLEISLRAFVGAPDGSFELRRSDVGSYDNPAAVGEALART
LLDDGAGAVIPPREAPNPTTSTKEAGA
>D1CBT4|hydroxymethylbilane synthase|EC 2.5.1.61|Thermobaculum terrenum (strain ATCC BAA-798 / YNP1)|TrEMBL
MKVIKVGTRGSKLALWQTQWVINRLRSLYPGFQFEPVVIKVTSDRSPDAPISAIGQVGVF
TKDIEQALLAGDIHLAVHSLKDLPTLSTPGTVIAAFTEREDPRDCILWPKGQPMPDLNNS
RVGTSSVRRSALVRSYWPNANVVNLRGNVDTRVRKMLEGNYDVVLMAYAAVKRMDLPVEF
KPLPLDSWVPSAGQGIIAVQAREDDQQIIGMLNAINFFPSKVAYLAERSLMRALGGGCSM
PVGAYAELHDGELSLIGMVAAPDGSQVVITRRVDTPDQADHLGERVAREMLDLGIRLTIS
>H3U7G2|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21345|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEI
IKRLNEQH
>B9XN63|hydroxymethylbilane synthase|EC 2.5.1.61|Pedosphaera parvula Ellin514|TrEMBL
MSSENNKPIFIATRGSALALAQANAVLSQCRSAFPKLDIELKIIKTTGDKLQKASLAKEG
ESLPKGLFTKELEVALLNGDADIAVHSLKDLPTELPTGLILGAVSKRADVRDVLVYRDAE
YLRSQPGKSNRRGFTPKLAIKDFPPGATVATSSTRRKAQLLAQRGDLNVVEIRGNVATRL
EKLANQPELDATVLAAAGLERLNFKITAEGKLAGEGIPEGLLATILDFDVMLPCVGQAAL
GMEIRENDARIQEICDRLNHPETHACVLAERSFLSGMGGGCQSPVAAYAEIAGDQLQMRA
ASFRETSARRAVGGKSINEAVALGQELAAKLK
>I0CRZ1|hydroxymethylbilane synthase|EC 2.5.1.61|Listeria monocytogenes 07PF0776|TrEMBL
MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGL
FVSEVEQALSDEVIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNRVNSLDELPQ
GSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLE
NTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKL
NGGCEIPIAGFATRANEVVHFKGLVGNADGSIILASEQAGANPSEIGNKVAEDLLSEGAD
TIIKELRNI
>I5W704|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4439|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>Q40KD3|hydroxymethylbilane synthase|EC 2.5.1.61|Ehrlichia chaffeensis str. Sapulpa|TrEMBL
MNIRIGTRGSILAIAQTLEIKNLLNRYFPEISVQIVKIKTSGDINNQVPLSAIGGKSLFI
KEIEEALLMGKVDLAVHSVKDIPAFYCEGLIIPCVLKRNSPYDVFISSKHKDIKSLPLNA
TIGTSSVRRKVQLNYLRPDLQVVPVRGNIDTRILKANVGEFDGIVLAEAGLIRINRCDVI
KEILSPKIMLSAVGQGAIGIQCRVDDHSIINKIKVLNCHQSYVCVMAERSFLKTINGSCD
TPLAALAQYVNNDTIHMSCMLANEKNMVFASCCFNECDAEKSGINMGKKLMDELSQYY
>D6DY52|hydroxymethylbilane synthase|EC 2.5.1.61|Eubacterium rectale DSM 17629|TrEMBL
MRYLIGTRGSKLALVQTDYVIDKLKRAYPDDDFKAVIIKTTGDLEQKKALDKIGSKGIFV
KEIEDELLSGKIHMAVHSMKDMPDEPAAGLTFAKAWKREDPRDVLVLKNAASLDELPHGA
VIGTGSKRRKYQLLKLRPDLKVVGIRGNIDTRLRKLYDGEIIYEEVADNTVNNNEIANEK
QNKYNEYRLDGIVLAAAGIKRIGRDSEITQYFSEDDMIPAPAQGTLALELRADNAKLMAK
LDALSDEKTNLCAGIEREFLKQIGGNCHLPVAAYCDIVSEKDRGNDSNKNNRLKLLAMFG
SEDGKQLARTEQVWDMTSDRNNIVERAVHDIRYKLESN
>H3YGI1|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus IS-105|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>A7IEG4|hydroxymethylbilane synthase|EC 2.5.1.61|Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)|TrEMBL
MSENTKSVYHPVHPRLRIGTRGSPLALWQAHAVQAALAVALGVEKEAIAVEVIKTSGDQI
QDRALSEAGGKGLFTKEIEEALLDGRVDLAVHSAKDVATVLPDGLHLAGYLPRADVRDAL
ILKSGAALADLPAGAKVGTASLRREAQLRRIRPDLKVELLRGNVHTRLAKVKDGDFDATL
LALAGLTRLGMAQAASCVLATDDFLPAVGQGAVAIECRIADPDTNAAIAAIACRDTGIAL
EAERAFLAALDGSCRTPIAGLATVEGESVRLRGLVLSPDGSDAAEIAELAPIADAARLGA
ECGARLRTSAPARALGL
>F6FVP5|hydroxymethylbilane synthase|EC 2.5.1.61|Isoptericola variabilis (strain 225)|TrEMBL
MSTPAEPGTAPLRLGTRGSALAMTQSGMVARRLTELLGRPVELVRIRTEGDVKTGSLASL
GGTGVFVTALREALLDGRCDVAVHSLKDLPTTQPPELTVVTPEREDPRDVLCARDGLTLE
TLPRGSRVGTGSPRRAAQLKAARPDVEIVDIRGNVDTRLARALGPEADLDAVVLAHAGLT
RLGRTDVVTEVLPPGVVAPAPGQGALAVEARTADLQPGAPDGGALARAFAALDHRATRVA
VIAERTVLARLEAGCAAPVGAYARVEDGALHLGAVVARVDGTEQLKHRASVELAAEMSTA
ALDAVATELGERVAEALLADGADRLAPLRPGTSAASPELPTGASRRVDSAPLHSPTGTDD
PEGA
>Q1EPC9|hydroxymethylbilane synthase|EC 2.5.1.61|Musa acuminata|TrEMBL
MLSGDRNEQSRPRCGWPIRTHYPLLIHGESVTNSTRSESRPRQSPFPCASRPLFSPFFLP
AQSSEPLLQPRWSPCDAPPRTTPCSARRPASCARGGGRAPWCALPWQWRPARRPRSPSSG
LGRDSPLALAQAHETREKLKAAHSELAEEGAIEIVIIKTTGDMILDKPLADIGGKGLFTK
EIDDALLQGRIDIAVHSMKDVPTYLPEGTILPCNLPREDVRDAFICLTANSLAELPAGSV
VGSASLRRQSQILYRYPSLKVVNFRGNVQTRLRKLKEGDVSATLLALAGLRRLNMAENAT
AVLSVEEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLAVLDGNCRT
PIAAYAYRDEDGNCSFRGLLASPDGSKVFETTRSGPYSFDDMVELGKDAGHELKAKAGPG
FFDSLQ
>H1Z8J7|hydroxymethylbilane synthase|EC 2.5.1.61|Myroides odoratus DSM 2801|TrEMBL
MDRVIRIGTRDSELAMWQATTVEKALNALGYKTELVPVKSEGDLVLDKPLYEMGITGIFT
KTLDVAMINKKVDIAVHSMKDVPTALPQGIVQAAVLQRANTVDILLHKGDTSFLDPAVEA
IVATGSLRRKAQWLNRFPKHTLVDLRGNVNTRMQKLADNEAWKGAIFASAGLDRIKKKPK
GFINLDWMIPAPAQGAMVVVAMADDSFALDALRQLNDYEAEMTTHIERQFLRTLEGGCTA
PIGAIATYNQKEETIDFTGVLLSLDGKEKFEINKTVPIQEWKKLGFFAAQELLANGGQAL
MEKLRQELKR
>E7YUC9|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. 81038-01|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H5PRM5|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC15A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHKTALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F5QC25|hydroxymethylbilane synthase|EC 2.5.1.61|Shigella flexneri 2747-71|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLCALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGEAPA
>G2JAB9|hydroxymethylbilane synthase|EC 2.5.1.61|Candidatus Glomeribacter gigasporarum BEG34|TrEMBL
MKNALVIASRKSPLALRQAEEVRAALQKLYPQSEISILGITTRGDQWLDQPLSKIGGKGL
FIKELEQALADGRADLAVHSLKDMPAVLPAGFKLAAIPERADPRDAFVCHRYLSLDTLPA
GSVVGTSSLRRAAMVRAHYPRLNVQPLRGNLDTRLRALDAGACTAMILAAAGLIRLGLEQ
RIRALLAPELSLPAASQGALGIEIREDRPEIADWLAPLNHLKTALAVYAERTVARALGGN
CAIPLAAFAEWIEGILLLRACIAQPDGARFLRARACAAPNTLAEAETLGYTVADDLARQG
AQEMVRAFSEQ
>F8FNS0|hydroxymethylbilane synthase|EC 2.5.1.61|Paenibacillus mucilaginosus (strain KNP414)|TrEMBL
MIDHLREICRQNGIEAEFELKKIVTKGDRILDVTLSKVGGKGLFVKEIEQALLDGEVDLA
VHSMKDMPFELPEGLVVGAVPLREDPRDCLIMREGKTIDDLPQGAKVGTSSLRRASQLQH
YRPDLKIEPIRGNIDSRLRKLETEGFDAILLAAAGLHRIGWSDRISSYLPPELCLPAVGQ
GALCIECRSDNDFVLNLLSKYLHEPTAVAVAAERSFLGRLNGGCQVPIGAYGELTGDKND
GRPEVKLTGMVGSPDGQQMLKETRTGTDPERLGRELAEALIAKGAAELLAAAREE
>A1VRW1|hydroxymethylbilane synthase|EC 2.5.1.61|Polaromonas naphthalenivorans (strain CJ2)|TrEMBL
MAAALQTFPSTLKVVIATRESRLAMWQAEHVKALLESRLGWQVELLGMTTLGDQILDRSL
SKVGGKGLFVKELEVALSEGRADLAVHSLKDVPMDLPEGFALACVLEREDPHDAFVSNDF
ASLAELPPGAVVGTSSLRRLVLLKALRPDLAIQPLRGNLDTRLRKLDEGQYQAIVLAAAG
LKRLGLESRIRHTFAPTDMLPAAGQGALGIEVRADRADLIAALATLAHQPTWLAVTAERT
VSRAMGGSCSMPLAAFVTAGSDGALQLDAAWGDPATADASSGVSAVLPAPLVQVRQTAVV
RSFAEAEALGDAVAAQLRAGGAVWASNAPAA
>I5QKH0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli TW09098|TrEMBL
MASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPV
EFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRS
LRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRL
DDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPD
GSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>F0N4B5|hydroxymethylbilane synthase|EC 2.5.1.61|Neisseria meningitidis serogroup B (strain M04-240196)|TrEMBL
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKG
LFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMP
EGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLELD
GRIRMILSESESLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAR
ELIGAVLNTEN
>F9R1A0|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli XH140A|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>F5M5G7|hydroxymethylbilane synthase|EC 2.5.1.61|Rhodobacter sphaeroides WS8N|TrEMBL
MPTPAEPLKIGTRGSPLALAQAYETRSRLSAAFSLPEEAFEIVVIKTTGDKVLDRPLKEI
GGKGLFTREIEEALLSGGIDIAVHSMKDMPTLQPEGLILDTYLPREDTRDAFITFADGGL
ADLPQGATVGSSSLRRRAQLLNKRPDLQVVEFRGNLQTRLKKLNDGVARGTFLAMAGLNR
LKMDEVPRVPIEPEEMLSAVAQGAIGIERRTDDPRAQEMLAAIHDVRTGHRLAAERSFLL
KLDGSCETPIAGLAILEGDQLWLRGEILRPDGSESISGEIRGAIADAAALGSELASELLG
RAPADFFSWR
>I2S9R6|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli 5.0588|TrEMBL
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAK
VGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDS
LDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLK
RLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELL
NNGAREILAEVYNGDAPA
>F8LAW6|hydroxymethylbilane synthase|EC 2.5.1.61|Waddlia chondrophila 2032/99|TrEMBL
MSSKPFPTLSTNRITVAARSSPLSEAQVDEILYEAQLIQPTLEFEVTLVTTLGDRDQESS
LRTLEKTDFFTRDIDQLLLNGYCRIAVHSAKDLPDPIPNGLNIIAVNQGLDPSDSLVMRP
GDTLSSLPKGAKIATSSIRREKAVHSLRSDLEVVDIRGNIGQRLQKLNDREVDGVIVAES
ALIRLNLYHLNRIHLPGETAPGQGKLAVVAREDDEEAAVFFSAMDQRPITVYLGLKPPKD
TAIKKFHHCPIIEIVPKIRSTRPLPPFTHIVFTSKSAVKIFCCYFDPKGLMDKTVIAVGT
QTAQGLIDCGVDVDYMPEVESSEGLIALLETLNLQDAQIFWPHSALSRPVITDYLTNKQI
PFTEWVIYTTIPREPTPLPEEF
>B3H1P2|hydroxymethylbilane synthase|EC 2.5.1.61|Actinobacillus pleuropneumoniae serotype 7 (strain AP76)|TrEMBL
MMNLPMKDTLRIATRQSPLALWQANFVKDELEKRFPELSVELVTMVTKGDVILDTPLAKI
GGKGLFVKELELALLENRADIAVHSMKDVPMTFPEGLGLAVICEREDPRDAFVSNKYQNL
DELPAGAVVGTSSLRRQCQLMAKYPHLEVKSLRGNVGTRLSKLDNGEYDAIILASAGLIR
LGMPERIRSFISVEQSLPAAGQGAVGIETRVDDERVLNYLATLNHNPTACCVIAERAMNT
RLQGGCQVPIGGFATLNGNEITLNALVGALDGSNIIRASGVADRENAEQLGISVAEQLLA
QGADKILAEVYKDE
>H0LYY2|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035318|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>I5SBM1|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli EC4203|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>H0AW72|hydroxymethylbilane synthase|EC 2.5.1.61|Staphylococcus aureus subsp. aureus 21209|TrEMBL
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLF
VKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEG
SIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDD
IVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEI
IKRLNEQH
>C7PKZ4|hydroxymethylbilane synthase|EC 2.5.1.61|Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034)|TrEMBL
MNREIKIGTRDSQLALWQANKVKGLLEAQGYSTVLVPIKSEGDIDLVTPLYEIGVQGIFT
KSLDIALLNGRIDIAVHSLKDVPTQLPKNIIQAAVLERGPVKDLLVYRQDTAFLGQPEYI
ANIATSSVRRKAQWLRKYPKHQLHNLRGNVNTRLQKLAAENWDGAIFAAAGLERIGVRPA
TSIELDWMLPAPAQGAVVAVCREDDDFCRQACAPFNDLATALCTRVERDFLRTLMGGCTT
PISAYATISNETVHFSGELCSLDGQQLFTITEQLPLQDAGVIGRSAAEKILAQGGDKIVA
EIKNAIK
>D9QE48|hydroxymethylbilane synthase|EC 2.5.1.61|Corynebacterium pseudotuberculosis (strain C231)|TrEMBL
MTFTIGTRGSLLATTQSGHVRDALISQGYSAELSIVTTPGDVNMAPVERIGVGVFTQALR
DVLVKGGCDIAVHSFKDLPTQRDPRFHLIVPERADARDCLVARDGLTLAELPQGARIGTG
APRRISQIKALRPDVECVPLRGNIDTRMGKVFSGELDAVVLAYAGLSRVGRGDEATEVFN
PERFLPAPAQGALAIECRVDDAAAVAAINAIRNAEDETCALAERVVLNRLEAGCTAPVAA
HSVIIEQELQVTGAVISLDGSKVFRATMTGGLSEAVAIGEKVAAKLIQDGAAELLS
>E4THE1|hydroxymethylbilane synthase|EC 2.5.1.61|Calditerrivibrio nitroreducens (strain DSM 19672 / NBRC 101217 / Yu37-1)|TrEMBL
MEKITIATRGSKLALWQANHIKSLLTNRYPEMLVELKIIKTQGDIILDVPLAKIGGKGLF
VKEIENALIENEADLAVHSMKDVPVELPDELEIYVNPHRESPFDAFLSVKYNNLDELPRG
AKLGTSSLRRKVQISRIRPDIEITDLRGNVDTRIRKLTEGTFDAIILARAGLNRLNLLEW
AKYTFDDSEIVPSVCQGTLGIEVRKDDDRIKNILKFMKDEKTEIVTRAERAFLRRLEGGC
QAPIGGYCKIEGGKLKMIGFLSSLDGDEFLKYEEYGDMDKPEVLGESVAEKILINGGKKI
LDDIYARS
>H7GIY0|hydroxymethylbilane synthase|EC 2.5.1.61|Thermus sp. RL|TrEMBL
MRVVVVGTRGSALALAQTRFVVERLKESWPETEFKIRTIKTRGDQGASPREEAIFVKEIQ
EALLSREIDIAVHSLKDLPTQSPKGLKIASVPRRQDPRDVFLGKAAKRLKDLPPGAVVGT
SSVRRKAQILALRPDLVVRDLRGNVDTRLAALGSGEYDGIVLAAAGLIRLDLRNRIDEFL
DPAEILPAPGQGALALEVREGDDLAEELCYALHHPPSYHRVRAERAFLRGLGAGCLAPVG
ALAHVEEDGTLRLEGVLLTPDGKSFIRAEIEGDVSEAEELGLDLARDVLEQGGREILAQI
R
>G8Q5V7|hydroxymethylbilane synthase|EC 2.5.1.61|Pseudomonas fluorescens F113|TrEMBL
MSPREIRIATRKSALALWQAEYVKARLEAAHPGLIVTLVPMVSRGDKLLDSPLSKIGGKG
LFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTFSSLEALP
AGSVVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFE
ERITSAISVDDSLPAGGQGAVGIECRSADSDIHALLAPLHHEDTATRVFAERALNKHLNG
GCQVPIACYAVLEGEQVWLRGLVGDPNGGRLLSAEARAPRHDAEALGVRVAEDLLSQGAA
DILKAVYGEAGHT
>H0MQ27|hydroxymethylbilane synthase|EC 2.5.1.61|Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035321|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLDNGDYDAIILAVAGLKRLGLE
SRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGAR
AILTEVYNGETPA
>H5HF28|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli DEC11C|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAR
EILAEVYNGDAPA
>D2NDM4|hydroxymethylbilane synthase|EC 2.5.1.61|Escherichia coli O150:H5 (strain SE15)|TrEMBL
MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKG
LFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALP
AGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLE
SRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAERAMNTRLEG
GCQVPIGSYAELIDGEIWLRALVGAPDGSLIIRGERRGAPQDAEQMGISLAEELLNNGAR
EILAEVYNGDA