indole-3-glycerol-phosphate synthase from Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (4.1.1.48) : Q06121 Range:

TRPC_SULSO

(indole-3-glycerol-phosphate synthase from Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2); EC 4.1.1.48)

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O

Accession Code:	Q06121
Organism:	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Number of AA:	248
Molecular Weight:	28588
Source:	Swiss-Prot

Sequences with same EC No.:

Sequence: ->fasta

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download all sequences with EC 4.1.1.48 in fasta format

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0	MPRYLKGWLK DVVQLSLRRP SFRASRQRPI ISLNERILEF NKRNITAIIA EYKRKSPSGL
60	DVERDPIEYS KFMERYAVGL SILTEEKYFN GSYETLRKIA SSVSIPILMK DFIVKESQID
120	DAYNLGADTV LLIVKILTER ELESLLEYAR SYGMEPLIEI NDENDLDIAL RIGARFIGIN
180	SRDLETLEIN KENQRKLISM IPSNVVKVAE SGISERNEIE ELRKLGVNAF LIGSSLMRNP
240	EKIKEFIL

Data linked to the same EC Number and organism:

PDB ID:

Sequence related references:

Sequence Reference Authors Title Journal Volume Pages Year Link to PubMed

165404 Tutino M.L.,Scarano G.,Marino G.,Sannia G.,Cubellis M.V. Tryptophan biosynthesis genes trpEGC in the thermoacidophilic archaebacterium Sulfolobus solfataricus. J. Bacteriol. 175 299 - 302 1993 PubMed

165406 She Q.,Singh R.K.,Confalonieri F.,Zivanovic Y.,Allard G.,Awayez M.J.,Chan-Weiher C.C.-Y.,Clausen I.G.,Curtis B.A.,De Moors A.,Erauso G.,Fletcher C.,Gordon P.M.K.,Heikamp-de Jong I.,Jeffries A.C.,Kozera C.J.,Medina N.,Peng X.,Thi-Ngoc H.P.,Redder P.,Schenk M.E.,Theriault C.,Tolstrup N.,Charlebois R.L.,Doolittle W.F.,Duguet M.,Gaasterland T.,Garrett R.A.,Ragan M.A.,Sensen C.W.,Van der Oost J. The complete genome of the crenarchaeon Sulfolobus solfataricus P2. Proc. Natl. Acad. Sci. U.S.A. 98 7835 - 7840 2001 PubMed

165407 Hennig M.,Darimont B.,Kirschner K.,Jansonius J.N. 2.0-A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability. Structure 3 1295 - 1306 1995 PubMed

165408 Knoechel T.R.,Hennig M.,Merz A.,Darimont B.,Kirschner K.,Jansonius J.N. The crystal structure of indole-3-glycerol phosphate synthase from the hyperthermophilic archaeon Sulfolobus solfataricus in three different crystal forms: effects of ionic strength. J. Mol. Biol. 262 502 - 515 1996 PubMed

Sequence Reference	Authors	Title	Journal	Volume	Pages	Year	Link to PubMed
165404	Tutino M.L.,Scarano G.,Marino G.,Sannia G.,Cubellis M.V.	Tryptophan biosynthesis genes trpEGC in the thermoacidophilic archaebacterium Sulfolobus solfataricus.	J. Bacteriol.	175	299 - 302	1993	PubMed
165406	She Q.,Singh R.K.,Confalonieri F.,Zivanovic Y.,Allard G.,Awayez M.J.,Chan-Weiher C.C.-Y.,Clausen I.G.,Curtis B.A.,De Moors A.,Erauso G.,Fletcher C.,Gordon P.M.K.,Heikamp-de Jong I.,Jeffries A.C.,Kozera C.J.,Medina N.,Peng X.,Thi-Ngoc H.P.,Redder P.,Schenk M.E.,Theriault C.,Tolstrup N.,Charlebois R.L.,Doolittle W.F.,Duguet M.,Gaasterland T.,Garrett R.A.,Ragan M.A.,Sensen C.W.,Van der Oost J.	The complete genome of the crenarchaeon Sulfolobus solfataricus P2.	Proc. Natl. Acad. Sci. U.S.A.	98	7835 - 7840	2001	PubMed
165407	Hennig M.,Darimont B.,Kirschner K.,Jansonius J.N.	2.0-A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability.	Structure	3	1295 - 1306	1995	PubMed
165408	Knoechel T.R.,Hennig M.,Merz A.,Darimont B.,Kirschner K.,Jansonius J.N.	The crystal structure of indole-3-glycerol phosphate synthase from the hyperthermophilic archaeon Sulfolobus solfataricus in three different crystal forms: effects of ionic strength.	J. Mol. Biol.	262	502 - 515	1996	PubMed