EC Number   |
Protein Variants |
Reference |
|---|
    1.13.11.34 | A603L |
site-directed mutagenesis, almost inactive mutant |
741918 |
| 1.13.11.34 | A603L/Y181A |
site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme |
741918 |
| 1.13.11.34 | C159S |
site-directed mutagenesis, the mutant shows altered susceptibillity to 2-aminothiazole inhibitors compared to the wild-type enzyme |
741862 |
| 1.13.11.34 | C159S/C300S/C416S/C418S |
site-directed mutagenesis, the mutant shows unaltered product synthesis |
741975 |
| 1.13.11.34 | C240A |
site-directed mutagenesis, the mutation renders the enzyme less susceptible to product inactivation |
741918 |
| 1.13.11.34 | C300S |
site-directed mutagenesis, the mutant shows altered susceptibillity to 2-aminothiazole inhibitors compared to the wild-type enzyme |
741862 |
| 1.13.11.34 | C416S |
site-directed mutagenesis, the mutant shows altered susceptibillity to 2-aminothiazole inhibitors compared to the wild-type enzyme |
741862 |
| 1.13.11.34 | C418S |
site-directed mutagenesis, the mutant shows altered susceptibillity to 2-aminothiazole inhibitors compared to the wild-type enzyme |
741862 |
| 1.13.11.34 | C561A |
site-directed mutagenesis, the mutation renders the enzyme less susceptible to product inactivation |
741918 |
| 1.13.11.34 | D170S/G174N |
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme |
741918 |
