EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
3.6.1.1 | 0.0333 |
- |
5-(4-bromophenyl)-3-(3-(3-chlorophenyl)pyrrolidin-1-yl)-1,2,4-triazine |
at pH 7.5 and 37°C |
733503 |
3.6.1.1 | 0.0383 |
- |
3-(3-(3-chlorophenyl)pyrrolidin-1-yl)-5-(5-(2-(trifluoromethyl)phenyl)furan-2-yl)-1,2,4-triazine |
at pH 7.5 and 37°C |
733503 |
3.6.1.1 | 0.0532 |
- |
3-(3-(3-chlorophenyl)pyrrolidin-1-yl)-5-(3,4-dimethoxyphenyl)-1,2,4-triazine |
at pH 7.5 and 37°C |
733503 |
3.6.1.1 | 0.0574 |
- |
3-(3-(3-(3-chlorophenyl)pyrrolidin-1-yl)-1,2,4-triazin-5-yl)aniline |
at pH 7.5 and 37°C |
733503 |
3.6.1.1 | 0.0632 |
- |
3-(3-(3-(benzyloxy)phenyl)pyrrolidin-1-yl)-5-(5-methylfuran-2-yl)-1,2,4-triazine |
at pH 7.5 and 37°C |
733503 |
3.6.1.1 | 0.0881 |
- |
4-(3-(3-(3-chlorophenyl)pyrrolidin-1-yl)-1,2,4-triazin-5-yl)aniline |
at pH 7.5 and 37°C |
733503 |
3.6.1.1 | 0.1 |
- |
fluoride |
potent inhibition, IC50: 0.1 mM |
667352 |
3.6.1.1 | 0.1015 |
- |
3-(3-(3-chlorophenyl)pyrrolidin-1-yl)-5-phenyl-1,2,4-triazine |
at pH 7.5 and 37°C |
733503 |
3.6.1.1 | 0.1182 |
- |
3-(3-(3-chlorophenyl)pyrrolidin-1-yl)-5-(3-nitrophenyl)-1,2,4-triazine |
at pH 7.5 and 37°C |
733503 |
3.6.1.1 | 0.1475 |
- |
3-[3-(3-chlorophenyl)pyrrolidin-1-yl]-5-(5-methylfuran-2-yl)-1,2,4-triazine |
at pH 7.5 and 37°C |
733503 |