EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.205 | IMP dehydrogenase |
glioblastoma cell |
- |
761406, 761611 |
1.1.1.27 | L-lactate dehydrogenase |
glioblastoma cell |
- |
740254 |
1.1.1.41 | isocitrate dehydrogenase (NAD+) |
glioblastoma cell |
- |
712180 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
glioblastoma cell |
- |
712180, 713508 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
glioblastoma cell |
multiforme tumors |
712614 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
glioblastoma cell |
of secondary glioblastomas |
713100 |
1.14.11.29 | hypoxia-inducible factor-proline dioxygenase |
glioblastoma cell |
- |
744649 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
glioblastoma cell |
cell line A-172, american type |
440219 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
glioblastoma cell |
- |
690140, 690143 |
1.14.19.17 | sphingolipid 4-desaturase |
glioblastoma cell |
- |
744418 |
1.21.99.3 | thyroxine 5-deiodinase |
glioblastoma cell |
- |
644797 |
1.4.3.13 | protein-lysine 6-oxidase |
glioblastoma cell |
- |
689199 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
glioblastoma cell |
expression of isoform Nox4 mRNA in glioblastomas of WHO grade IV is significantly higher than other astrocytomas of WHO grades II and III |
687150 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
glioblastoma cell |
- |
705274, 718566, 719586, 733083, 735326, 757010, 758542 |
2.1.1.77 | protein-L-isoaspartate(D-aspartate) O-methyltransferase |
glioblastoma cell |
80% reduced PIMT expression as compared to normal brains |
659913 |
2.1.2.1 | glycine hydroxymethyltransferase |
glioblastoma cell |
in human glioblastoma multiforme, mitochondrial serine hydroxymethyltransferase (SHMT2) and glycine decarboxylase are highly expressed in the pseudopalisading cells that surround necrotic foci |
736882 |
2.1.2.2 | phosphoribosylglycinamide formyltransferase 1 |
glioblastoma cell |
- |
736945 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
glioblastoma cell |
- |
736889 |
2.3.1.48 | histone acetyltransferase |
glioblastoma cell |
from brain tumor |
735770 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
glioblastoma cell |
isoform TG2 activity is elevated in glioblastomas compared with non-neoplastic brain |
676265 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
glioblastoma cell |
isoform TG2 activity is eleveated in glioblastomas compared with non-neoplastic brain |
676265 |
2.3.3.8 | ATP citrate synthase |
glioblastoma cell |
- |
704077, 718760 |
2.4.1.101 | alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
glioblastoma cell |
MGAT1 is highly expressed in glioblastoma tissues |
759196 |
2.4.2.3 | uridine phosphorylase |
glioblastoma cell |
UPP1 is significantly upregulated in glioma, especially in glioblastoma |
758991 |
2.4.2.4 | thymidine phosphorylase |
glioblastoma cell |
- |
759610 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
glioblastoma cell |
- |
677920 |
2.5.1.46 | deoxyhypusine synthase |
glioblastoma cell |
- |
723584 |
2.6.1.42 | branched-chain-amino-acid transaminase |
glioblastoma cell |
- |
759414 |
2.7.1.1 | hexokinase |
glioblastoma cell |
human glioblastoma multiforme shows increased HK2 expression, correlating with poor overall survival |
722876 |
2.7.1.105 | 6-phosphofructo-2-kinase |
glioblastoma cell |
- |
739045, 761915 |
2.7.1.107 | diacylglycerol kinase (ATP) |
glioblastoma cell |
- |
761306 |
2.7.1.137 | phosphatidylinositol 3-kinase |
glioblastoma cell |
primary glioblastoma |
685959 |
2.7.1.147 | ADP-specific glucose/glucosamine kinase |
glioblastoma cell |
- |
723169 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
glioblastoma cell |
- |
761163 |
2.7.1.32 | choline kinase |
glioblastoma cell |
- |
641353, 663274 |
2.7.1.91 | sphingosine kinase |
glioblastoma cell |
- |
674904 |
2.7.10.1 | receptor protein-tyrosine kinase |
glioblastoma cell |
- |
490215, 661551 |
2.7.11.12 | cGMP-dependent protein kinase |
glioblastoma cell |
- |
762071 |
2.7.11.23 | [RNA-polymerase]-subunit kinase |
glioblastoma cell |
- |
741006 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
glioblastoma cell |
- |
742223 |
2.7.2.3 | phosphoglycerate kinase |
glioblastoma cell |
- |
761885 |
2.7.6.1 | ribose-phosphate diphosphokinase |
glioblastoma cell |
cell line |
642731 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase |
glioblastoma cell |
- |
722415 |
2.7.7.19 | polynucleotide adenylyltransferase |
glioblastoma cell |
- |
762042 |
2.7.7.52 | RNA uridylyltransferase |
glioblastoma cell |
high activity |
761888 |
2.8.2.33 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase |
glioblastoma cell |
- |
726319 |
3.1.2.6 | hydroxyacylglutathione hydrolase |
glioblastoma cell |
glioblastoma multiform cells |
37413 |
3.1.3.4 | phosphatidate phosphatase |
glioblastoma cell |
- |
716195 |
3.1.3.48 | protein-tyrosine-phosphatase |
glioblastoma cell |
- |
710396 |
3.1.3.5 | 5'-nucleotidase |
glioblastoma cell |
Rugli cells |
95056 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
glioblastoma cell |
expression of mutant forms of PTEN |
650911 |
3.1.3.86 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
glioblastoma cell |
- |
749524, 751179 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
glioblastoma cell |
- |
696397, 728853 |
3.1.6.2 | steryl-sulfatase |
glioblastoma cell |
- |
681649 |
3.2.1.166 | heparanase |
glioblastoma cell |
- |
754394 |
3.2.1.24 | alpha-mannosidase |
glioblastoma cell |
- |
665978 |
3.4.14.5 | dipeptidyl-peptidase IV |
glioblastoma cell |
- |
709456 |
3.4.21.26 | prolyl oligopeptidase |
glioblastoma cell |
- |
709456 |
3.4.21.73 | u-Plasminogen activator |
glioblastoma cell |
- |
709905 |
3.4.21.B10 | neurosin |
glioblastoma cell |
- |
732960 |
3.4.21.B28 | fibroblast activation protein alpha subunit |
glioblastoma cell |
- |
707629 |
3.4.21.B28 | fibroblast activation protein alpha subunit |
glioblastoma cell |
glioma stem-like cell, isolated from a solid glioblastoma in a long term culture, low expression |
707629 |
3.4.22.1 | cathepsin B |
glioblastoma cell |
- |
707157 |
3.4.22.1 | cathepsin B |
glioblastoma cell |
expression of cathepsins B, L and S gradually increases in the progression from benign astrocytoma to the malignant glioblastoma |
710205 |
3.4.22.1 | cathepsin B |
glioblastoma cell |
the most frequent malignant brain tumor in adults, increased expression of cathepsin B compared to healthy astrocytes, immunohistochemic and expression analysis, overview |
707002 |
3.4.22.1 | cathepsin B |
glioblastoma cell |
upregulation of CatB |
707625 |
3.4.22.15 | cathepsin L |
glioblastoma cell |
- |
712921 |
3.4.22.38 | cathepsin K |
glioblastoma cell |
cathepsin K, the chemo-attractant stromal-derived factor-1alpha and its C-X-C receptor type 4 are localized in therapy-resistant glioma stem-like cell (GSLC) niches in glioblastoma |
752841 |
3.4.22.53 | calpain-2 |
glioblastoma cell |
- |
718169, 732365 |
3.4.22.60 | caspase-7 |
glioblastoma cell |
- |
700938 |
3.4.23.45 | memapsin 1 |
glioblastoma cell |
- |
638894 |
3.4.24.23 | matrilysin |
glioblastoma cell |
- |
683864 |
3.4.24.24 | gelatinase A |
glioblastoma cell |
- |
734254, 752865 |
3.4.24.24 | gelatinase A |
glioblastoma cell |
the enzyme is upregultaed compared to control brain |
733634 |
3.4.24.35 | gelatinase B |
glioblastoma cell |
- |
707452, 710225 |
3.4.24.35 | gelatinase B |
glioblastoma cell |
the enzyme is upregulated compared to control brain |
733634 |
3.4.24.81 | ADAM10 endopeptidase |
glioblastoma cell |
- |
754777 |
3.4.24.82 | ADAMTS-4 endopeptidase |
glioblastoma cell |
- |
668982 |
3.4.24.B10 | ADAM12 endopeptidase |
glioblastoma cell |
- |
667133 |
3.4.24.B12 | ADAMTS5 endopeptidase |
glioblastoma cell |
- |
667106 |
3.4.25.1 | proteasome endopeptidase complex |
glioblastoma cell |
- |
667212 |
3.5.1.23 | ceramidase |
glioblastoma cell |
- |
754949 |
3.5.4.37 | double-stranded RNA adenine deaminase |
glioblastoma cell |
- |
756885, 757225 |
3.5.4.37 | double-stranded RNA adenine deaminase |
glioblastoma cell |
ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis |
720608 |
3.6.1.9 | nucleotide diphosphatase |
glioblastoma cell |
- |
756172 |
3.6.5.2 | small monomeric GTPase |
glioblastoma cell |
- |
700896 |
4.1.1.17 | ornithine decarboxylase |
glioblastoma cell |
- |
680257 |
4.1.1.28 | aromatic-L-amino-acid decarboxylase |
glioblastoma cell |
- |
716172 |
4.1.3.4 | hydroxymethylglutaryl-CoA lyase |
glioblastoma cell |
HMGCLL1 |
727926 |
4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase |
glioblastoma cell |
- |
705324, 747508 |
5.1.1.18 | serine racemase |
glioblastoma cell |
cell line U87, inverse regulation of enzyme activity by D-serine and nitric oxide |
662958 |
5.3.99.5 | thromboxane-A synthase |
glioblastoma cell |
- |
706861 |
6.3.1.2 | glutamine synthetase |
glioblastoma cell |
- |
745832 |
7.2.2.3 | P-type Na+ transporter |
glioblastoma cell |
- |
747716 |