EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
HCT-116 cell |
- |
668160 |
1.1.1.21 | aldose reductase |
HCT-116 cell |
- |
713006 |
1.1.1.21 | aldose reductase |
HCT-116 cell |
colon cancer cell line |
668165 |
1.1.1.27 | L-lactate dehydrogenase |
HCT-116 cell |
- |
740254 |
1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
HCT-116 cell |
colon cancer cell line |
712676 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
HCT-116 cell |
- |
739163, 761332 |
1.1.1.428 | 4-methylthio 2-oxobutanoate reductase (NADH) |
HCT-116 cell |
- |
764279 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
HCT-116 cell |
- |
740161 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
HCT-116 cell |
cultured cells, expresses 17beta-HSD isoforms 1-4 |
656644 |
1.1.1.64 | testosterone 17beta-dehydrogenase (NADP+) |
HCT-116 cell |
- |
740912 |
1.10.5.1 | ribosyldihydronicotinamide dehydrogenase (quinone) |
HCT-116 cell |
- |
711408, 711470 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
HCT-116 cell |
- |
712088, 712799, 728416 |
1.14.11.30 | hypoxia-inducible factor-asparagine dioxygenase |
HCT-116 cell |
- |
764068 |
1.14.11.53 | mRNA N6-methyladenine demethylase |
HCT-116 cell |
- |
764080 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
HCT-116 cell |
- |
753296, 755238 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
HCT-116 cell |
- |
758189 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
HCT-116 cell |
- |
733488 |
1.14.19.17 | sphingolipid 4-desaturase |
HCT-116 cell |
- |
745595 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
HCT-116 cell |
- |
753296, 755238 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
HCT-116 cell |
BALB c nu/nu athymic nude mice are implanted with the human colorectal cancer HCT-116 cells |
711769 |
1.17.4.2 | ribonucleoside-triphosphate reductase (thioredoxin) |
HCT-116 cell |
colon cancer cell. Cell line expresses subunit R2 in excess resulting in protection against DNA damage and replication stress |
671925 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
HCT-116 cell |
- |
676259 |
1.3.1.1 | dihydropyrimidine dehydrogenase (NAD+) |
HCT-116 cell |
colorectal cancer cells |
712566 |
1.3.1.2 | dihydropyrimidine dehydrogenase (NADP+) |
HCT-116 cell |
colorectal cancer cells |
712566 |
1.3.5.2 | dihydroorotate dehydrogenase (quinone) |
HCT-116 cell |
- |
763351 |
1.4.3.13 | protein-lysine 6-oxidase |
HCT-116 cell |
- |
686947 |
1.5.1.2 | pyrroline-5-carboxylate reductase |
HCT-116 cell |
- |
674605 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
HCT-116 cell |
- |
693945, 712692, 713005, 713018, 724516 |
1.8.1.4 | dihydrolipoyl dehydrogenase |
HCT-116 cell |
immunochemical analysis of dihydrolipoamide dehydrogenase protein levels |
743767 |
1.8.1.9 | thioredoxin-disulfide reductase |
HCT-116 cell |
- |
698055 |
1.8.1.9 | thioredoxin-disulfide reductase |
HCT-116 cell |
human colon cell adenocarcinoma |
689708 |
2.1.1.2 | guanidinoacetate N-methyltransferase |
HCT-116 cell |
- |
705727 |
2.1.1.233 | [phosphatase 2A protein]-leucine-carboxy methyltransferase |
HCT-116 cell |
- |
715490 |
2.1.1.244 | protein N-terminal methyltransferase |
HCT-116 cell |
- |
758296 |
2.1.1.299 | protein N-terminal monomethyltransferase |
HCT-116 cell |
- |
758296 |
2.1.1.319 | type I protein arginine methyltransferase |
HCT-116 cell |
- |
756861 |
2.1.1.348 | mRNA m6A methyltransferase |
HCT-116 cell |
- |
745434 |
2.1.1.357 | [histone H3]-lysine36 N-dimethyltransferase |
HCT-116 cell |
- |
754870 |
2.1.1.366 | [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase |
HCT-116 cell |
- |
759019, 759760 |
2.1.1.45 | thymidylate synthase |
HCT-116 cell |
- |
756169, 757252 |
2.1.1.B128 | 28S rRNA (adenine1322-N1)-methyltransferase |
HCT-116 cell |
- |
758419 |
2.2.1.1 | transketolase |
HCT-116 cell |
- |
691270, 691299 |
2.3.1.147 | glycerophospholipid arachidonoyl-transferase (CoA-independent) |
HCT-116 cell |
- |
676922 |
2.3.1.24 | sphingosine N-acyltransferase |
HCT-116 cell |
- |
736471 |
2.3.1.255 | N-terminal amino-acid Nalpha-acetyltransferase NatA |
HCT-116 cell |
- |
702870 |
2.3.1.257 | N-terminal L-serine Nalpha-acetyltransferase NatD |
HCT-116 cell |
- |
735456, 756385 |
2.3.1.258 | N-terminal methionine Nalpha-acetyltransferase NatE |
HCT-116 cell |
- |
740792 |
2.3.1.291 | sphingoid base N-palmitoyltransferase |
HCT-116 cell |
- |
752815 |
2.3.1.48 | histone acetyltransferase |
HCT-116 cell |
- |
719989, 736055, 756653 |
2.3.1.48 | histone acetyltransferase |
HCT-116 cell |
colon tumor cell line |
675911 |
2.3.1.57 | diamine N-acetyltransferase |
HCT-116 cell |
- |
757889 |
2.3.1.57 | diamine N-acetyltransferase |
HCT-116 cell |
the enzyme is inducible in response to 5-fluorouracil or oxaliplatin in parental and drugresistant HCT116 cell lines |
675916 |
2.3.1.85 | fatty-acid synthase system |
HCT-116 cell |
- |
704079 |
2.3.2.32 | cullin-RING-type E3 NEDD8 transferase |
HCT-116 cell |
- |
745773 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
HCT-116 cell |
- |
759031 |
2.3.3.8 | ATP citrate synthase |
HCT-116 cell |
- |
736093 |
2.4.1.244 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase |
HCT-116 cell |
- |
736917 |
2.4.1.274 | glucosylceramide beta-1,4-galactosyltransferase |
HCT-116 cell |
- |
755974 |
2.4.1.90 | N-acetyllactosamine synthase |
HCT-116 cell |
- |
755974 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
HCT-116 cell |
- |
701720, 721934, 735758, 735766, 735872, 736436, 736612, 737279 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HCT-116 cell |
- |
756666 |
2.5.1.18 | glutathione transferase |
HCT-116 cell |
- |
759611 |
2.5.1.58 | protein farnesyltransferase |
HCT-116 cell |
- |
721819 |
2.7.1.105 | 6-phosphofructo-2-kinase |
HCT-116 cell |
- |
698929, 730530, 737974, 749587, 751761 |
2.7.1.105 | 6-phosphofructo-2-kinase |
HCT-116 cell |
PFKFB3 is overexpressed in human cancers |
737997 |
2.7.1.105 | 6-phosphofructo-2-kinase |
HCT-116 cell |
PFKFB4 is overexpressed in human cancers |
730530 |
2.7.1.137 | phosphatidylinositol 3-kinase |
HCT-116 cell |
HCT-116 cells are heterozygous for gain of function mutant PIK3CA H1047R |
709003 |
2.7.1.147 | ADP-specific glucose/glucosamine kinase |
HCT-116 cell |
- |
739468 |
2.7.1.151 | inositol-polyphosphate multikinase |
HCT-116 cell |
- |
739703 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
HCT-116 cell |
- |
709907 |
2.7.1.21 | thymidine kinase |
HCT-116 cell |
- |
722681 |
2.7.1.32 | choline kinase |
HCT-116 cell |
- |
738968 |
2.7.1.40 | pyruvate kinase |
HCT-116 cell |
- |
723269, 761027, 761028, 761609 |
2.7.1.74 | deoxycytidine kinase |
HCT-116 cell |
- |
721556, 738770 |
2.7.1.82 | ethanolamine kinase |
HCT-116 cell |
- |
739083, 739440 |
2.7.10.1 | receptor protein-tyrosine kinase |
HCT-116 cell |
- |
691396 |
2.7.10.2 | non-specific protein-tyrosine kinase |
HCT-116 cell |
- |
673029 |
2.7.11.10 | IkappaB kinase |
HCT-116 cell |
- |
762079 |
2.7.11.13 | protein kinase C |
HCT-116 cell |
- |
737786 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
HCT-116 cell |
- |
721971, 738836, 760260 |
2.7.11.20 | elongation factor 2 kinase |
HCT-116 cell |
- |
740996, 760307, 760308, 760810, 760850 |
2.7.11.21 | polo kinase |
HCT-116 cell |
- |
691300, 702558, 703026, 705620 |
2.7.11.22 | cyclin-dependent kinase |
HCT-116 cell |
- |
691256, 691272, 737959, 738159, 739059 |
2.7.12.1 | dual-specificity kinase |
HCT-116 cell |
- |
741257 |
2.7.12.2 | mitogen-activated protein kinase kinase |
HCT-116 cell |
- |
740419 |
2.7.4.14 | UMP/CMP kinase |
HCT-116 cell |
- |
702166 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
HCT-116 cell |
- |
723635, 761474, 761492 |
2.7.4.24 | diphosphoinositol-pentakisphosphate 1-kinase |
HCT-116 cell |
- |
761474 |
2.7.4.9 | dTMP kinase |
HCT-116 cell |
- |
691610 |
2.7.6.2 | thiamine diphosphokinase |
HCT-116 cell |
- |
762080 |
2.7.7.1 | nicotinamide-nucleotide adenylyltransferase |
HCT-116 cell |
- |
737990 |
2.7.7.49 | RNA-directed DNA polymerase |
HCT-116 cell |
- |
694207 |
2.7.7.6 | DNA-directed RNA polymerase |
HCT-116 cell |
- |
705982 |
2.7.7.7 | DNA-directed DNA polymerase |
HCT-116 cell |
- |
691631, 705655 |
2.8.2.5 | chondroitin 4-sulfotransferase |
HCT-116 cell |
- |
760531 |
3.1.1.118 | phospholipid sn-1 acylhydrolase |
HCT-116 cell |
- |
761626 |
3.1.21.10 | crossover junction endodeoxyribonuclease |
HCT-116 cell |
- |
683782 |
3.1.26.3 | ribonuclease III |
HCT-116 cell |
- |
729852 |
3.1.3.16 | protein-serine/threonine phosphatase |
HCT-116 cell |
- |
679065 |
3.1.3.3 | phosphoserine phosphatase |
HCT-116 cell |
- |
749807 |