EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.205 | IMP dehydrogenase |
B-lymphocyte |
- |
667976, 668295, 669800 |
1.1.1.205 | IMP dehydrogenase |
B-lymphocyte |
highest expression |
761406 |
1.13.11.34 | arachidonate 5-lipoxygenase |
B-lymphocyte |
- |
704997, 711100, 742001, 743614 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
B-lymphocyte |
- |
660498 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
B-lymphocyte |
- |
757745 |
1.21.99.3 | thyroxine 5-deiodinase |
B-lymphocyte |
- |
733907 |
1.3.5.1 | succinate dehydrogenase |
B-lymphocyte |
- |
689710 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
B-lymphocyte |
- |
742310 |
1.8.1.9 | thioredoxin-disulfide reductase |
B-lymphocyte |
development and differentiation of the cells from transgenic mice lacking Txnrd2 expression is not significantly impaired |
685444 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
B-lymphocyte |
- |
704942 |
2.3.2.23 | E2 ubiquitin-conjugating enzyme |
B-lymphocyte |
- |
759492 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
B-lymphocyte |
secretory and non-secretory cell line P3X63Ag8 |
487989 |
2.4.1.122 | N-acetylgalactosaminide beta-1,3-galactosyltransferase |
B-lymphocyte |
- |
693931 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
B-lymphocyte |
splenic |
638236 |
2.4.1.212 | hyaluronan synthase |
B-lymphocyte |
expression of HAS1 splice variants is absent from B cells of healthy donors and in multiple myeloma and monoclonal gammopathy of undetermined significance (MGUS) is restricted to the B-cell compartment |
672775 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
B-lymphocyte |
- |
706744 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
B-lymphocyte |
- |
737400 |
2.7.1.137 | phosphatidylinositol 3-kinase |
B-lymphocyte |
- |
640869, 640892, 640899, 707454 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
B-lymphocyte |
- |
760061 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
B-lymphocyte |
- |
709350 |
2.7.1.40 | pyruvate kinase |
B-lymphocyte |
M2-type isoenzyme |
721719 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
B-lymphocyte |
- |
721555 |
2.7.1.74 | deoxycytidine kinase |
B-lymphocyte |
- |
723637 |
2.7.10.2 | non-specific protein-tyrosine kinase |
B-lymphocyte |
- |
490669, 693031 |
2.7.11.10 | IkappaB kinase |
B-lymphocyte |
peripheral |
662569 |
2.7.11.13 | protein kinase C |
B-lymphocyte |
- |
660959, 661549, 662293, 662928 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
B-lymphocyte |
- |
491278 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
B-lymphocyte |
the enzyme is absent from primary human B lymphocytes but is expressed in Epstein-Barr virus-transformed B-lymphoblastoid cell lines, suggesting that expression of the kinase can be upregulated by an EBV gene products |
491289 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
B-lymphocyte |
- |
-, 681911 |
2.7.12.1 | dual-specificity kinase |
B-lymphocyte |
- |
741322 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
B-lymphocyte |
- |
704625 |
2.7.7.19 | polynucleotide adenylyltransferase |
B-lymphocyte |
- |
761995 |
2.7.7.31 | DNA nucleotidylexotransferase |
B-lymphocyte |
exclusively express hTdTS and hTdTl2 |
662574 |
2.7.7.7 | DNA-directed DNA polymerase |
B-lymphocyte |
- |
703394, 703546 |
2.7.8.1 | ethanolaminephosphotransferase |
B-lymphocyte |
- |
737738 |
2.7.8.2 | diacylglycerol cholinephosphotransferase |
B-lymphocyte |
- |
674897, 737738 |
3.1.1.53 | sialate O-acetylesterase |
B-lymphocyte |
- |
715136 |
3.1.1.53 | sialate O-acetylesterase |
B-lymphocyte |
catalytic regulation of B cell receptor (BCR) signalling and B-cell development, knockout mice: striking decrease in number of splenic marginal zone B-cells and marginal zone B-cell precursors, reduced number in follicular B-cells, loss of recirculating B-cells in bone marrow, lymphocyte-intrinsic defects |
699276 |
3.1.3.16 | protein-serine/threonine phosphatase |
B-lymphocyte |
primary |
-, 665666 |
3.1.3.48 | protein-tyrosine-phosphatase |
B-lymphocyte |
- |
693943, 694165, 752091 |
3.1.3.5 | 5'-nucleotidase |
B-lymphocyte |
- |
692592 |
3.1.3.5 | 5'-nucleotidase |
B-lymphocyte |
CD73 is a lymphocyte surface antigen |
716355 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
B-lymphocyte |
- |
694494, 694495 |
3.1.4.11 | phosphoinositide phospholipase C |
B-lymphocyte |
mechanosensitive activation of K+ channel via phospholipase C-induced depletion of phosphatidylinositol 4,5-bisphosphate |
681604 |
3.1.4.3 | phospholipase C |
B-lymphocyte |
low level of enzyme expression |
679640 |
3.2.1.49 | alpha-N-acetylgalactosaminidase |
B-lymphocyte |
inducible enzyme |
663573 |
3.2.2.27 | uracil-DNA glycosylase |
B-lymphocyte |
- |
732835 |
3.2.2.5 | NAD+ glycohydrolase |
B-lymphocyte |
- |
670293 |
3.2.2.5 | NAD+ glycohydrolase |
B-lymphocyte |
surface |
668457 |
3.4.11.18 | methionyl aminopeptidase |
B-lymphocyte |
- |
697409 |
3.4.11.7 | glutamyl aminopeptidase |
B-lymphocyte |
immature B-lineage cell |
663609 |
3.4.14.5 | dipeptidyl-peptidase IV |
B-lymphocyte |
- |
649282, 663815 |
3.4.14.5 | dipeptidyl-peptidase IV |
B-lymphocyte |
cell surface |
649276 |
3.4.16.5 | carboxypeptidase C |
B-lymphocyte |
- |
703982 |
3.4.17.12 | carboxypeptidase M |
B-lymphocyte |
- |
697395 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
B-lymphocyte |
- |
699124 |
3.4.21.20 | cathepsin G |
B-lymphocyte |
- |
665912, 709987 |
3.4.21.79 | granzyme B |
B-lymphocyte |
IL-21 and GzmB serum levels are highly correlated in subjects with systemic lupus erythematosus and freshly isolated CD51 systemic lupus erythematosus B cells constitutively express GzmB |
708381 |
3.4.22.1 | cathepsin B |
B-lymphocyte |
- |
-, 709368, 709979 |
3.4.22.1 | cathepsin B |
B-lymphocyte |
primary |
708694 |
3.4.22.1 | cathepsin B |
B-lymphocyte |
primary, expression analysis, overview |
707640 |
3.4.22.15 | cathepsin L |
B-lymphocyte |
- |
679329 |
3.4.22.27 | cathepsin S |
B-lymphocyte |
- |
679696, 696630, 696638, 696641, 696743, 698859, 699142, 699442, 753968 |
3.4.22.34 | Legumain |
B-lymphocyte |
EBV-infected |
650474 |
3.4.22.36 | caspase-1 |
B-lymphocyte |
- |
699419 |
3.4.22.54 | calpain-3 |
B-lymphocyte |
- |
649028 |
3.4.22.57 | caspase-4 |
B-lymphocyte |
primary, activated |
718292 |
3.4.22.59 | caspase-6 |
B-lymphocyte |
- |
-, 699336 |
3.4.22.60 | caspase-7 |
B-lymphocyte |
B cells derived from cavity-based B cell lymphoma |
717785 |
3.4.22.61 | caspase-8 |
B-lymphocyte |
- |
665922, 696593 |
3.4.22.61 | caspase-8 |
B-lymphocyte |
caspase-8 is dispensable for B-cell development, but its loss in B cells results in attenuated antibody production upon in vivo viral infection. Important role for caspase-8 in maintaining B-cell survival following stimulation of the Toll-like receptor (TLR)2, -3, and -4 |
680886 |
3.4.22.62 | caspase-9 |
B-lymphocyte |
10C9 |
663674 |
3.4.23.34 | cathepsin E |
B-lymphocyte |
- |
696014 |
3.4.23.B24 | signal peptide peptidase |
B-lymphocyte |
- |
752819, 754400, 755089 |
3.4.23.B24 | signal peptide peptidase |
B-lymphocyte |
B-cell line A20 |
754400 |
3.4.24.81 | ADAM10 endopeptidase |
B-lymphocyte |
- |
679354, 720159 |
3.4.25.1 | proteasome endopeptidase complex |
B-lymphocyte |
immortalized with Epstein Barr virus |
720802 |
3.5.1.60 | N-(long-chain-acyl)ethanolamine deacylase |
B-lymphocyte |
- |
-, 754356 |
3.5.4.38 | single-stranded DNA cytosine deaminase |
B-lymphocyte |
- |
720141, 720456, 720460, 720538, 720891, 720914 |
3.5.4.38 | single-stranded DNA cytosine deaminase |
B-lymphocyte |
AID expression occurs first in pro-B cells and increases on further development, peak AID expression is in immature and T1 B cells from bone marrow, is lower in splenic T1 B cells, and decreases precipitously in the splenic transitional 2 and mature B-cell compartments |
720915 |
3.5.4.38 | single-stranded DNA cytosine deaminase |
B-lymphocyte |
germinal center B-cell |
720890 |
3.5.4.38 | single-stranded DNA cytosine deaminase |
B-lymphocyte |
the enzyme is specifically expresssed in germinal center B-cells |
719247 |
3.5.4.4 | adenosine deaminase |
B-lymphocyte |
- |
712672 |
3.6.1.5 | apyrase |
B-lymphocyte |
- |
-, 756375 |
3.6.5.2 | small monomeric GTPase |
B-lymphocyte |
- |
-, 734407 |
3.6.5.2 | small monomeric GTPase |
B-lymphocyte |
Rap1b is more highly expressed in B cells than Rap1a |
720356 |
4.1.1.22 | histidine decarboxylase |
B-lymphocyte |
- |
690301 |
4.1.2.27 | sphinganine-1-phosphate aldolase |
B-lymphocyte |
circulating T lymphocyte |
728089 |
4.3.2.2 | adenylosuccinate lyase |
B-lymphocyte |
- |
693982 |
4.6.1.1 | adenylate cyclase |
B-lymphocyte |
forskolin-insensitive AC isoforms in various B cell populations |
691711 |
5.3.4.1 | protein disulfide-isomerase |
B-lymphocyte |
cell surface |
661243 |
6.3.2.17 | tetrahydrofolate synthase |
B-lymphocyte |
- |
745104 |
7.4.2.14 | ABC-type antigen peptide transporter |
B-lymphocyte |
- |
762296 |