EC Number   |
General Information |
Reference |
|---|
  2.3.1.B36 | evolution |
evolution of the GPCAT family in eukaryotes, phylogenetic tree, evolutionary analysis, overview. GPCAT does not show any significant homology to other known acyl transferases and constitutes an enzyme family on its own with homologues represented in major eukaryotic organism groups but absent in prokaryotes |
-, 757164 |
| 2.3.1.B36 | metabolism |
the enzyme provides a distinct route of resynthesising phosphatidylcholine via lysophosphatidylcholine after its deacylation. This route does not require the degradation of the glycerophosphocholine into free choline, the activation of choline to CDP-choline, nor the utilization of CDP-choline by the CDP-choline:diacylglycerol cholinephosphotransferase. GPCAT activity plays a ubiquitous role inplant lipid metabolism |
737051 |
| 2.3.1.B36 | metabolism |
the enzyme provides a novel route of resynthesising phosphatidylcholine via lysophosphatidylcholine after its deacylation. This route does not require the degradation of the glycerophosphocholine into free choline, the activation of choline to CDP-choline, nor the utilization of CDP-choline by the CDP-choline:diacylglycerol cholinephosphotransferase. GPCAT activity plays a ubiquitous role inplant lipid metabolism |
737051 |
| 2.3.1.B36 | more |
GPCAT enzyme activity in microsomal membrane preparations from Arabidopsis thaliana roots and leaves occurs at much lower activity level compared to oil seed membranes, e.g. from safflower (Carthamus tinctorius), castor bean (Ricinus communis), elm (Ulmus glabra), and rape seed (Brassica napus) |
737051 |
| 2.3.1.B36 | more |
GPCAT enzyme activity in microsomal membrane preparations from Brassica napus oil seeds occurs at about 50% lower activity level compared to oil seed membranes from safflower (Carthamus tinctorius), castor bean (Ricinus communis), and elm (Ulmus glabra) |
737051 |
| 2.3.1.B36 | more |
GPCAT enzyme activity in microsomal membrane preparations from Crambe abyssinica oil seeds occurs at much lower activity level compared to oil seed membranes from safflower (Carthamus tinctorius), castor bean (Ricinus communis), and elm (Ulmus glabra) |
737051 |
| 2.3.1.B36 | physiological function |
cellular role for Gpc1p in the synthesis of phosphocholine via acylation of GPC. GPCAT is also unique in that it has, in addition to acyl-CoA acyltransferase activity, LPC:GPC transacylase activity |
-, 757164 |
| 2.3.1.B36 | physiological function |
glycerophosphocholine:acyl-CoA acyltransferase (GPCAT) activity provides a distinct direct route of phosphatidylcholine resynthesis via lysophosphatidylcholine following its deacylation. GPCAT and not acyl-CoA:lysophosphatidylcholine acyltransferase (LPCAT) is the limiting step in the formation of phosphatidylcholine |
737051 |
| 2.3.1.B36 | physiological function |
glycerophosphocholine:acyl-CoA acyltransferase (GPCAT) activity provides a distinct direct route of phosphatidylcholine resynthesis via lysophosphatidylcholine following its deacylation. GPCAT and not acyl-CoA:lysophosphatidylcholine acyltransferase (LPCAT), which is catalyzing the next step in the pathway, is the limiting step in the formation of phosphatidylcholine |
737051 |
