EC Number   |
General Information |
Reference |
|---|
    1.1.1.284 | evolution |
GSNOR belongs to the class III alcohol dehydrogenase family |
763054 |
| 1.1.1.284 | evolution |
GSNOR expression and activity during development of Solanum spp. genotypes |
763592 |
| 1.1.1.284 | evolution |
GSNOR is a member of class III alcohol dehydrogenase family |
763600 |
| 1.1.1.284 | evolution |
GSNOR is evolutionarily conserved, it is reclassified as S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284). FALDH and ADH3 are identical enzymes. GSNOR also is a Zn-dependent medium-chain class III alcohol dehydrogenase (ADH3, EC 1.1.1.1). GSNOR also is glutathione-dependent formaldehyde dehydrogenase (FALDH, EC 1.2.1.1) |
763605 |
| 1.1.1.284 | evolution |
GSNOR is evolutionarily conserved, it is reclassified as S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284). FALDH and ADH3 are identical enzymes. GSNOR also is a Zn-dependent medium-chain class III alcohol dehydrogenase (ADH3, EC 1.1.1.1). GSNOR also is glutathione-dependent formaldehyde dehydrogenase (FALDH, EC 1.2.1.1). Eukaryotic GSNORs are highly conserved and unusually cysteine-rich proteins |
763605 |
| 1.1.1.284 | evolution |
S-nitrosoglutathione reductase (GSNOR) is highly conserved enzyme amongst eukaryotes and prokaryotes. It is a member of the class III alcohol dehydrogenase family |
762617 |
| 1.1.1.284 | evolution |
the enzyme belongs to the large alcohol dehydrogenase superfamily, namely to the class III ADHs |
-, 724489 |
| 1.1.1.284 | malfunction |
a fast increase in S-nitrosothiol content and a reduction of the leaf photosynthesis ratio are a result of suppressed GSNOR activity with specific inhibitors |
763605 |
| 1.1.1.284 | malfunction |
a potential role of GSNOR in plant resistance to herbivory Manduca sexta is examined in coyote tobacco (Nicotiana attenuata) plants using a virus-induced silencing of GSNOR. GSNOR-silenced plants are more susceptible to herbivore attack and decreased the herbivore-induced accumulation of phytohormones jasmonic acid (JA) and ethylene and activity of trypsin proteinase inhibitors |
763605 |
| 1.1.1.284 | malfunction |
Arabidopsis thaliana plants overexpressing the GSNOR gene exhibit increased nitrate reductase (NR) activity, conversely, GSNOR mutant plants show a significant decrease in NR activity. GSNOR enzymatic activity, but not gene expression, is inhibited by the nitrogen assimilatory pathway via post-transcriptional S-nitrosation, preventing any scavenging of GSNO. Enzymatic activity of GSNOR is essential for the acclimation of Arabidopsis thaliana plants to high temperature, since HOT5 mutants, plants with defect GSNOR gene, are more sensitive to high temperature as a consequence of disturbed homeostasis of S-nitrosothiols and NO-derived ROS signaling pathways. Enzyme mutant Nox1 is an NO overproducing plant with higher levels of L-arginine and L-citrulline, while mutant Gsnor1-3 is a plant with reduced GSNOR activity with higher levels of NO, S-nitrosothiols, and nitrate. Gsnor1-3 mutant Arabidopsis thaliana plants with a high S-nitrosothiols level show an increased selenite tolerance. high NO level, due to the reduced GSNOR activity, increases sensitivity under mild stress conditions, while it supports tolerance under severe stress conditions. Gsnor1-3 mutant plants with a high S-nitrosothiols level show an increased selenite tolerance |
763605 |
