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EC Number
Expression
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Reference
3.2.2.27
down
depletion of endogenous UNG2 is proteasome-dependent and requires a direct interaction with HIV Vpr but not with integrase, different capacity between HIV-1 and HIV-2 to inhibit intracellular UNG2 expression
710139
3.2.2.27
down
protein and mRNA levels rapidly decline in G2/M phase. Micro-RNAs down-regulate enzyme activity, mRNA, and protein levels by directly targeting the conserved seed sites in the 3'-untranslated region
731707
3.2.2.27
up
UDG expression is upregulated 1.75fold in SUMO-1 overexpressing HepG2 cells, SUMO-1 is involved in protein sumoylation
708025
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