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EC Number Reaction Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.55(2E,6E)-farnesyl diphosphate = (S)-beta-bisabolene + diphosphate (S)-beta-bisabolene is a stable intermediate. (S)-beta-Macrocarpene formation requires a protonation of the intermediate 704432
Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.55(2E,6E)-farnesyl diphosphate = (S)-beta-bisabolene + diphosphate The synthesis of (S)-beta-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps. The first step is the cyclization to (S)-beta-bisabolene. The second steps is the isomerization to (S)-beta-macrocarpene (c.f. EC 5.5.1.a, (S)-beta-macrocarpene synthase). The enzyme requires Mg2+ or Mn2+ for activity. 704432
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