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EC Number Posttranslational Modification Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B71ubiquitination SENP2 can be polyubiquitinated in vivo and degraded through proteolysis. Restricting SENP2 in the nucleus by mutations in the nuclear export signal (NES) impairs its polyubiquitination, whereas a cytoplasm-localized SENP2 made by introducing mutations in the nuclear localization signal (NLS) can be efficiently polyubiquitinated, suggesting that SENP2 is ubiquitinated in the cytoplasm 681909
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