EC Number   |
Application |
Reference |
|---|
   2.3.1.82 | analysis |
apication of the aacA-aphD gene as an efficient marker for plastid transformation. It produces similar numbers of transplastomic lines as the spectinomycin resistance gene aadA. When tethered to plastid expression signals, the aac6-aph2 gene provides sufficiently strong resistance to tobramycin and gentamicin to select plastid transformants in tobacco |
-, 758025 |
| 2.3.1.82 | medicine |
a C-14T mutation in eis confers kanamycin resistance in Mycobacterium tuberculosis |
706524 |
| 2.3.1.82 | medicine |
aac(6')-Iz is an important contributor to aminoglycoside resistance in clinical strains of Stenotrophomonas maltophilia |
658998 |
| 2.3.1.82 | medicine |
aminoglycoside N-6'-acetyltransferases are important determinants of antibiotic resistance |
703215 |
| 2.3.1.82 | medicine |
isolation of 85 clinical strains of Klebsiella pneumoniae and Escherichia coli that are believed to be aac(6')-Ib positive. Among them, 38 strains are wild-type, the remaining 47 strains harbour the aac(6')-Ib-cr variant that confers resistance against aminoglycoside and fluoroquinolone simultaneously. Of these 47 strains, 19 simultaneously harbor the aac(6')-Ib and aac(6')-Ib-cr gene |
719164 |
| 2.3.1.82 | medicine |
two isolates resistant to fluoroquinolones and beta-lactam antimicrobials show mutations in the quinolone resistance-determining regions of gene GyrA and of ParC as well as carrying a 150 kb plasmid harbouring the quinolone resistance gene qnrA1, the ciprofloxacin-modifying enzyme-encoding gene aac(6')-Ib-cr and genes encoding for extended-spectrum beta-lactamases such as blaSHV and blaCTX-M-3. When this large plasmid is transferred to Escherichia coli by conjugation, the transconjugants show a 10-75fold increase in the minimum inhibitory concentrations of ciprofloxacin and norfloxacin |
719603 |
