EC Number   |
Application |
Reference |
|---|
    1.1.1.42 | analysis |
simultaneous detection, quantitation and purification of glucose 6-phosphate dehydrogenase, malic enzyme, and NADP-dependent isocitrate dehydrogenase by blue native gel electrophoresis |
-, 668396 |
| 1.1.1.42 | biotechnology |
the icdA gene is a potentially valuable tool for modulating citric acid production by metabolic engineering |
740181 |
| 1.1.1.42 | diagnostics |
IDH1 codon 132 mutation is an important prognostic biomarker in gliomas. IDH1 mutation predicts outcome in grade 2, 3, and 4 gliomas |
712574 |
| 1.1.1.42 | diagnostics |
IDH1 mutational analysis can serve as a useful diagnostic marker of a glioma |
713508 |
| 1.1.1.42 | medicine |
sensitizing effect of NADP+-dependent isocitrate dehydrogenase siRNA on the apoptotic cell death of HeLa cells offers the possibility of developing a modifier of cancer therapy |
684887 |
| 1.1.1.42 | medicine |
the enzyme is a vaccine candidate against the fish pathogen Edwardsiella tarda infection. The serum of enzyme-vaccinated flounder exhibit the highest bactericidal activity compared with other groups. The recombinant enzyme can enhance the expressions of interferon-gamma, natural killer enhancing factor, interleukin-6, major histocompatibility complex Ialpha, CD4-1 and CD8alpha |
-, 762504 |
| 1.1.1.42 | medicine |
the sensitizing effect of IDPm siRNA and autophagy inhibitor on the ionizing radiation induced apoptotic cell death of glioma cells offers a novel redox-active therapeutic strategy for the treatment of cancer |
739984 |
| 1.1.1.42 | medicine |
the sensitizing effect of NADP+-dependent isocitrate dehydrogenase siRNA on the apoptotic cell death of HeLa cells offers the possibility of developing a modifier of cancer chemotherapy |
686864 |
| 1.1.1.42 | medicine |
transfection of HeLa cells with an NADP+-dependent isocitrate dehydrogenase small interfering RNA decreased the activity of IDPm, enhancing the susceptibility of radiation-induced apoptosis. The effect of NADP+-dependent isocitrate dehydrogenaseIDPm small interfering RNA on HeLa cells offers the possibility of developing a modifier of radiation therapy |
687547 |
| 1.1.1.42 | more |
future clinical and bioengineering applications of hICDH can be in the development of techniques to regulate the growth of glioblastomas and to capture and store carbon dioxide |
739770 |
