EC Number |
General Stability |
Reference |
---|
4.1.1.17 | 50% loss of activity after freezing and thawing of the purified enzyme |
4001 |
4.1.1.17 | after prolong storage, the protein loses its activity |
749234 |
4.1.1.17 | antizyme 3 stabilize the enzyme |
696119 |
4.1.1.17 | Crithidia fasciculata ODC, in contrast to other phylogentically related enzymes, is rapidly degraded also in mammalian systems, and it contains several sequence elements essential for the rapid turnover of the protein, these regions are mainly located in the central part of the enzyme, overview, half-life of the wild-type enzyme is 3.2 h |
695518 |
4.1.1.17 | dithiothreitol stabilizes |
4004 |
4.1.1.17 | dithiothreitol stabilizes the enzyme |
700873 |
4.1.1.17 | enzyme is sensitive to freeze-thawing |
666559 |
4.1.1.17 | formation of inactive forms in the absence of thiol-reducing agents |
4008 |
4.1.1.17 | lability increases during purification |
4029 |
4.1.1.17 | Leishmania donovani ODC has a very fast turnover in mammalian cells, but is a stable enzyme, half-life of the wild-type enzyme is 5.5 h |
695518 |