Information on EC 1.1.1.1 -

Information on EC 1.1.1.1 - alcohol dehydrogenase:

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EC NUMBER	COMMENTARY
1.1.1.1	-

RECOMMENDED NAME	GeneOntology No.
alcohol dehydrogenase	GO:0004025

REACTION	REACTION DIAGRAM	COMMENTARY	ORGANISM	UNIPROT ACCESSION NO.	LITERATURE
a primary alcohol + NAD+ = an aldehyde + NADH + H+		ordered bi bi mechanism with cofactor adding first to form a binary enzyme complex	Homo sapiens	-	285578
a primary alcohol + NAD+ = an aldehyde + NADH + H+		ordered bi-bi mechanism	Equus caballus	-	285586
a primary alcohol + NAD+ = an aldehyde + NADH + H+		isoenzyme EE and SS: ordered bi bi mechanism	Equus caballus	-	285590
a primary alcohol + NAD+ = an aldehyde + NADH + H+		Theorell-Chance mechanism	Scaptodrosophila lebanonensis	-	285593
a primary alcohol + NAD+ = an aldehyde + NADH + H+		kinetic mechanism is random for ethanol oxidation and compulsory ordered for acetaldehyde reduction	Equus caballus	-	285596
a primary alcohol + NAD+ = an aldehyde + NADH + H+		ordered bi-bi mechanism	Drosophila melanogaster	-	285598
a primary alcohol + NAD+ = an aldehyde + NADH + H+		rapid equilibrium random mechanism	Drosophila melanogaster, Drosophila simulans	-	285618
a primary alcohol + NAD+ = an aldehyde + NADH + H+		Theorell-Chance mechanism	Chlamydomonas moewusii	-	285624
a primary alcohol + NAD+ = an aldehyde + NADH + H+		Theorell-Chance mechanism	Brassica napus	-	285629
a primary alcohol + NAD+ = an aldehyde + NADH + H+		oxidizes ethanol in an ordered bi-bi mechanism with NAD+ as the first substrate fixed	Meyerozyma guilliermondii	-	285640
a primary alcohol + NAD+ = an aldehyde + NADH + H+		compulsory-order mechanism with the rate-limiting step being the dissociation of the product enzyme-NAD+ complex	Saccharomyces cerevisiae	-	285645
a primary alcohol + NAD+ = an aldehyde + NADH + H+		mechanism is predominantly ordered with ethanol, but partially random with butanol	Saccharomyces cerevisiae, Schizosaccharomyces pombe	-	285646
a primary alcohol + NAD+ = an aldehyde + NADH + H+		-	-	-	-
a primary alcohol + NAD+ = an aldehyde + NADH + H+		Ser48 is involved in catalysis, isozyme gamma(2)gamma(2)	Homo sapiens	-	654727
a primary alcohol + NAD+ = an aldehyde + NADH + H+		ordered bibi mechanism, structural and functional implications of amino acid residue 47	Mus musculus	Q9QYY9	654730
a primary alcohol + NAD+ = an aldehyde + NADH + H+		reaction mechanism, His51 is involved, but not essential, in catalysis facilitating the deprotonation of the hydroxyl group of water or alcohol ligated to the catalytic zinc	Equus caballus	-	654743
a primary alcohol + NAD+ = an aldehyde + NADH + H+		sequential reaction mechanism	Rhodococcus ruber	-	655082
a primary alcohol + NAD+ = an aldehyde + NADH + H+		ordered sequential bibi reaction mechanism, modeling of oxidation kinetic mechanism	Equus caballus	-	655233
a primary alcohol + NAD+ = an aldehyde + NADH + H+		detailed determination of the reaction and kinetic mechanisms, active site structure and determination of amino acid residues involved in catalysis, 3 isozymes	Saccharomyces cerevisiae	-	655649
a primary alcohol + NAD+ = an aldehyde + NADH + H+		class IV alcohol dehydrogenase also functions as retinol dehydrogenase, reaction and kinetic mechanism: asymmetric rapid equilibrium random mechanism with 2 dead-end ternary complexes fro retinol oxidation and a rapid equilibrium ordered mechanism with one dead-end ternary complex for retinal reduction, a unique mechanistic form fro zinc-containing ADH in the medium chain dehydrogenase/reductase superfamily of enzymes	Homo sapiens	-	656058
a primary alcohol + NAD+ = an aldehyde + NADH + H+		active site structure	Aeropyrum pernix	-	656525
a primary alcohol + NAD+ = an aldehyde + NADH + H+		the catalytic triad consists of Cys44, His67, and Cys154, active site structure	Pseudomonas aeruginosa	-	657302
a primary alcohol + NAD+ = an aldehyde + NADH + H+		catalytic mechanism involves a proton relay modulated by the coupled ionization of the active site Lys155/Tyr151 pair, and a NAD+ ribose 2'-OH switch, other active site residues are Ser138 and Trp144, ionization properties, substrate binding, overview	Scaptodrosophila lebanonensis	-	657317
a secondary alcohol + NAD+ = a ketone + NADH + H+		-	-	-	-

REACTION TYPE	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY	LITERATURE
oxidation	-	-	-	-
redox reaction	-	-	-	-
redox reaction	Rhodococcus erythropolis	-	-	658321
redox reaction	Zygosaccharomyces rouxii	-	-	658565
redox reaction	Acinetobacter calcoaceticus	-	-	659674
redox reaction	Neurospora crassa	-	-	659773
redox reaction	Mus musculus	-	-	697214
reduction	-	-	-	-

PATHWAY	KEGG Link	MetaCyc Link
3-methylbutanol biosynthesis	-	PWY-6871
acetaldehyde biosynthesis I	-	PWY-6333
acetoin degradation	-	PWY-6028
acetylene degradation	-	P161-PWY
chitin degradation to ethanol	-	PWY-7118
ethanol degradation I	-	ETOH-ACETYLCOA-ANA-PWY
ethanol degradation II	-	PWY66-21
heterolactic fermentation	-	P122-PWY
isobutanol biosynthesis	-	PWY-7111
isoleucine degradation II	-	PWY-5078
L-1,2-propanediol degradation	-	PWY-7013
leucine degradation III	-	PWY-5076
methionine degradation III	-	PWY-5082
mixed acid fermentation	-	FERMENTATION-PWY
noradrenaline and adrenaline degradation	-	PWY-6342
phenylalanine degradation III	-	PWY-5079
phenylethanol biosynthesis	-	PWY-5751
pyruvate fermentation to ethanol I	-	PWY-5480
pyruvate fermentation to ethanol II	-	PWY-5486
pyruvate fermentation to ethanol III	-	PWY-6587
salidroside biosynthesis	-	PWY-6802
serotonin degradation	-	PWY-6313
tryptophan degradation V (side chain pathway)	-	PWY-3162
tyrosine degradation III	-	PWY3O-4108
valine degradation II	-	PWY-5057

SYSTEMATIC NAME	IUBMB Comments
alcohol:NAD+ oxidoreductase	A zinc protein. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.

SYNONYMS	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY	LITERATURE
40 kDa allergen	-	-	-	-
ADH	-	-	-	-
ADH	Sulfolobus solfataricus	-	-	654684, 677301, 678116, 678121, 678363, 679816, 679883, 680428, 680442, 681372, 681763, 682627, 697839
ADH	Equus caballus	-	-	654743, 655233, 697215, 697669
ADH	Acetobacter pasteurianus	-	-	655058
ADH	Homo sapiens	-	-	655197, 655479, 691867, 697802
ADH	Mus musculus	-	-	655233, 655479, 697214
ADH	Thermomicrobium roseum	-	-	655262
ADH	Geobacillus stearothermophilus	-	-	656475
ADH	Aeropyrum pernix	-	-	656525
ADH	Pseudomonas aeruginosa	-	-	657302
ADH	Sulfolobus sp.	P50381	-	680428
ADH	Saccharomyces cerevisiae	-	-	695705, 696411, 697658, 697669, 699019
ADH	Thermus sp.	B2ZRE3	-	695811
ADH	Thermoanaerobacter brockii	-	-	697669
ADH	Anastrepha fraterculus, Anastrepha obliqua	-	-	698114
ADH	Euglena gracilis	B8QU18	-	699249
ADH	Thermoplasma acidophilum	Q9HIM3	-	700124
ADH 1	Mus musculus	-	-	699982
ADH II	Zymomonas mobilis	-	-	667340
ADH-A2	-	-	-	-
ADH-B2	-	-	-	-
ADH-C2	-	-	-	-
ADH-HT	-	-	-	-
ADH-I	Geobacillus thermoglucosidasius	Q6RS93	-	699071
ADH1	Pseudomonas putida	Q76HN6	-	678779
ADH1	Neurospora crassa	Q9P6C8	-	684614
ADH1	Saccharomyces carlsbergensis	B6UQD0	-	697267
ADH1	Saccharomyces cerevisiae	-	isozyme	697267
ADH1	Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962
ADH1C	Homo sapiens	P00326, P08319	isozyme	701322
ADH1C*1	Homo sapiens	-	-	655206
ADH1C*2	Homo sapiens	-	-	655206
Adh1p	Saccharomyces cerevisiae	-	-	688866
ADH2	Mus musculus	Q9QYY9	-	654730
ADH2	Entamoeba histolytica	-	-	655804, 656604
ADH2	Sulfolobus solfataricus	Q9UXF1	-	681629
ADH2	Saccharomyces cerevisiae	P00331	-	684586
ADH2	Saccharomyces cerevisiae	-	isozyme	697267
ADH2	Homo sapiens	P00326, P08319	isozyme	701322
ADH2	Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962
ADH3	-	-	-	-
ADH3	Mus musculus	-	-	667832, 697214
ADH3	Neurospora crassa	Q9P6C8	-	684614
ADH3	Homo sapiens	P00326, P08319	isozyme	701322
ADH4	Homo sapiens	-	-	656058
ADH4	Schizosaccharomyces pombe	Q09669	-	684960
ADH4	Homo sapiens	P00326, P08319	isozyme	701322
ADH8	Rana perezi	-	-	656168
AdhA	Picrophilus torridus	Q6L0S1	-	684620
AdhE	Thermoanaerobacter ethanolicus	Q0PH30	the purified AdhE exhibits high enzymatic activity attributed to aldehyde dehydrogenase and low alcohol dehydrogenase activity	695536
alcohol dehydrogenase (NAD)	-	-	-	-
alcohol dehydrogenase 1	Saccharomyces cerevisiae	-	-	688866
alcohol dehydrogenase 1	Saccharomyces cerevisiae	-	mutant enzyme S109P/L116S/Y294C	690211
alcohol dehydrogenase 1	Mus musculus	-	-	699982
alcohol dehydrogenase 3	Mus musculus	-	-	697214
alcohol dehydrogenase I	Saccharomyces cerevisiae	-	-	654053, 696411
alcohol dehydrogenase II	Zymomonas mobilis	-	-	667340
alcohol dehydrogenase II	Saccharomyces cerevisiae	P00331	-	684586
Alcohol dehydrogenase-B2	-	-	-	-
alcohol dependent dehydrogenase	Mus musculus	-	-	697214
alcohol-aldehyde/ketone oxidoreductase, NAD+-dependent	Sulfolobus solfataricus	-	the enzyme transfers the pro-R hydrogen from coenzyme to substrate and is therefore an A-specific dehydrogenase	678363
alcohol:NAD+ oxidoreductase	Saccharomyces cerevisiae	-	-	696411
Aldehyde reductase	-	-	-	-
aldehyde/alcohol dehydrogenase	Thermoanaerobacter ethanolicus	Q0PH30	-	695536
aliphatic alcohol dehydrogenase	-	-	-	-
class I ADH	Homo sapiens	-	isozyme	686331
class I ADH	Homo sapiens	-	isoenzyme	697802
class II ADH	Homo sapiens	-	isozyme	686331
class II ADH	Homo sapiens	-	isoenzyme	697802
class III alcohol dehydrogenase	Mus musculus	-	-	667832
class IV ADH	Homo sapiens	-	isozyme	686331
Cm-ADH2	Cucumis melo	-	-	670572
DADH	Scaptodrosophila lebanonensis	-	-	657317
dehydrogenase, alcohol	-	-	-	-
ethanol dehydrogenase	-	-	-	-
FALDH	-	-	-	-
FDH	-	-	-	-
Gastric alcohol dehydrogenase	-	-	-	-
Glutathione-dependent formaldehyde dehydrogenase	-	-	-	-
GSH-FDH	-	-	-	-
HLAD	Equus caballus	-	-	697660
HtADH	Geobacillus stearothermophilus	P42328	-	685180
KlADH4	Kluyveromyces lactis	-	-	668675
KlDH3	Kluyveromyces lactis	-	-	668675
KmADH3	Kluyveromyces marxianus	A1IIA3, A1IIA4	-	685652
KmADH4	Kluyveromyces marxianus	A1IIA3, A1IIA4	-	685652
long-chain alkyl alcohol dehydrogenase	Geobacillus thermodenitrificans	A4IP64, A4ISB9	;	712962
LSADH	Leifsonia sp.	-	-	667255
medium chain alcohol dehydrogenase	Aeropyrum pernix	-	-	656525
medium-chain NAD+-dependent ADH	Euglena gracilis	B8QU18	-	699249
medium-chain secondary alcohol dehydrogenase	Rhodococcus ruber	-	-	655082
NAD(H)-dependent alcohol dehydrogenase	Thermus thermophilus	-	-	684583
NAD+-ADH	Euglena gracilis	B8QU18	-	699249
NAD+-dependent (S)-stereospecific alcohol dehydrogenase	Sulfolobus solfataricus	-	-	697839
NAD-dependent alcohol dehydrogenase	-	-	-	-
NAD-specific aromatic alcohol dehydrogenase	-	-	-	-
NADH-alcohol dehydrogenase	-	-	-	-
NADH-aldehyde dehydrogenase	-	-	-	-
Octanol dehydrogenase	-	-	-	-
primary alcohol dehydrogenase	-	-	-	-
Retinol dehydrogenase	-	-	-	-
SCAD	Saccharomyces cerevisiae	-	-	687134
sec-ADH A	Rhodococcus ruber	-	-	655082
SSADH	Sulfolobus solfataricus	-	-	682630
Ta1316 ADH	Thermoplasma acidophilum	Q9HIM3	-	700124
TaDH	Thermus sp.	-	-	684246
TBADH	Thermoanaerobacter brockii	-	-	655735
Y-ADH	Saccharomyces cerevisiae	-	-	655741
YADH	Saccharomyces cerevisiae	-	-	655649, 655735, 685776
YADH-1	Saccharomyces cerevisiae	-	-	688657
yeast alcohol dehydrogenase	-	-	-	-

CAS REGISTRY NUMBER	COMMENTARY
9031-72-5	-

ORGANISM	COMMENTARY	LITERATURE	SEQUENCE CODE	SEQUENCE DB	SOURCE
Acetobacter pasteurianus	strain SKU1108, 2 soluble isozymes	655058	-	-
Acetobacter pasteurianus SKU1108	strain SKU1108, 2 soluble isozymes	655058	-	-
Acinetobacter calcoaceticus	-	659674	-	-
Aeropyrum pernix	-	656525	-	-
Alligator mississippiensis	-	285656	-	-
Anastrepha fraterculus	-	698114	-	-
Anastrepha obliqua	-	698114	-	-
Avena sativa	-	285635	-	-
Brassica napus	-	285629	-	-
Brevibacterium sp.	KU 1309	669540	-	-
Brevibacterium sp. KU 1309	KU 1309	669540	-	-
Camellia sinensis	-	285628	-	-
Candida parapsilosis	fragment; CCTCC M203011	684556	B2KJ46	UniProt
Candida parapsilosis CCTCC M203011	fragment; CCTCC M203011	684556	B2KJ46	UniProt
Candida sp.	N-16	285637	-	-
Candida sp. N-16	N-16	285637	-	-
Chlamydomonas moewusii	-	285624	-	-
Citrullus lanatus	-	285635	-	-
Corynebacterium glutamicum R	-	684612	-	-
Coturnix coturnix	japonica. ADH-1, ADH-2, ADH-3 and ADH-An	285615	-	-
Cricetulus griseus	-	285556	-	-
Crocus sativus	-	654140	-	-
Ctenopharyngodon idella	-	285557	-	-
Cucumis melo	var. Cantalupensis	670572	-	-
Cytophaga sp. KUC-1	strain KUC-1	668532	Q8L3C9	SwissProt
Desulfovibrio gigas	-	285654	-	-
Devosia riboflavina	KNK10702	688442	-	-
Devosia riboflavina KNK10702	KNK10702	688442	-	-
Dipodascus capitatus	-	687850	-	-
Drosophila funebris	-	285563	-	-
Drosophila immigrans	-	285563	-	-
Drosophila melanogaster	-	285563, 285618, 285619, 285620	-	-
Drosophila melanogaster	alleloenzyme AdhS	285617	-	-
Drosophila melanogaster	alleloenzymes Adhf and Adhus	285613	-	-
Drosophila melanogaster	alleloenzymes AdhS and AdhF	285598	-	-
Drosophila simulans	-	285563, 285618, 285619	-	-
Drosophila virilis	-	285563, 285619	-	-
Emericella nidulans	-	285636	-	-
Ensifer adhaerens S-5	probable alcohol dehydrogenase; strain S-5	678779	Q76HN6	UniProt
Entamoeba histolytica	-	285655	-	-
Entamoeba histolytica	strain HM1	656604	-	-
Entamoeba histolytica	strain HM1:1MSS, alcohol dehydrogenase 2	655804	-	-
Entamoeba histolytica HM1:1MSS	strain HM1:1MSS, alcohol dehydrogenase 2	655804	-	-
Equus caballus	-	285581, 285582, 285584, 285585, 285586, 285587, 285588, 285589, 285591, 285592, 285594, 285595, 285609, 285610, 285641, 285647, 285648, 285653, 285657, 655206, 655233, 668487, 685703, 695889, 697215, 697660	-	-
Equus caballus	-	654743, 685155, 697669	P00327	Uniprot
Equus caballus	isoenzymes EE, ES, and SS	285590	-	-
Equus caballus	SS isoenzyme	285583, 285596, 285597	-	-
Escherichia coli	-	660650	-	-
Euglena gracilis	strain Z	699249	B8QU18	Uniprot
Euglena gracilis Z	strain Z	699249	B8QU18	-
Euglena longa	-	285638	-	-
Flavobacterium frigidimaris	strain KUC-1	668532	Q8L3C9	SwissProt
Fragaria x ananassa	-	669027	-	-
Gallus gallus	-	285599	-	-
Geobacillus stearothermophilus	-	656475	-	-
Geobacillus stearothermophilus	-	685180	P42328	Uniprot
Geobacillus stearothermophilus	strain LLD-R	654751	P42328	Uniprot
Geobacillus stearothermophilus LLD-R	strain LLD-R	654751	P42328	-
Geobacillus thermodenitrificans	-	712962	A4IP64, A4ISB9	UniProt
Geobacillus thermoglucosidasius	strain M10EXG	699071	Q6RS93	UniProt
Geobacillus thermoglucosidasius M10EXG	strain M10EXG	699071	Q6RS93	UniProt
Glycine max	-	285635	-	-
Glycine max	4 isoenzymes	285626	-	-
Hafnia alvei	-	660650	-	-
Homo sapiens	-	285565, 285567, 285574, 654370, 669630, 686331, 687976, 689316, 691867, 697802	-	-
Homo sapiens	-	701322	P00326, P08319	UniProt
Homo sapiens	ADHIndianapolis form 1 and 2 and 3	285577	-	-
Homo sapiens	alcohol dehydrogenase 2, 2 allelic forms	655197	-	-
Homo sapiens	anodic enzyme form	285573	-	-
Homo sapiens	anodic enzyme form; chi-ADH	285576	-	-
Homo sapiens	class I enzyme, several isozymes	654727	-	-
Homo sapiens	class I isoenzymes: alpha,gamma2, gamma2gamma2, alpha,gamma1, alpha,beta1, beta1,gamma2, gamma1,gamma1, beta1,gamma1, beta1,beta1	285568	-	-
Homo sapiens	class II isoenzyme: pi-ADH	285569	-	-
Homo sapiens	class III isoenzyme	285566	-	-
Homo sapiens	class III isoenzyme; isoenzyme chi-ADH	285571	-	-
Homo sapiens	class IV alcohol dehydrogenase	656058	-	-
Homo sapiens	class IV enzyme, sigma-ADH	285608	-	-
Homo sapiens	isoenzyme alpha,alpha, beta1,beta1, gamma1,gamma1 and gamma2,gamma2	285572	-	-
Homo sapiens	isoenzyme pi	285578	-	-
Homo sapiens	isoenzymes beta1,beta1, beta2,beta2 and beta3,beta3	285575	-	-
Homo sapiens	isoenzymes: beta2beta2, beta2beta1, alphabeta2 and beta2gamma1	285570	-	-
Homo sapiens	isozyme 1C*2 (gamma2gamma2)	655206	-	-
Homo sapiens	isozymes ADH1B1, ADH1B2, and ADH4	655479	-	-
Homo sapiens	mue-alcolhol dehydrogenase	285651	-	-
Hordeum vulgare	3 isoenzymes	285634	-	-
Klebsiella oxytoca	-	660650	-	-
Klebsiella pneumoniae	-	660650	-	-
Kluyveromyces lactis	-	668675	-	-
Kluyveromyces marxianus	-	285558	-	-
Kluyveromyces marxianus	-	685652	A1IIA3, A1IIA4	SwissProt
Leifsonia sp.	strain S749	667255	-	-
Leifsonia sp. S749	strain S749	667255	-	-
Macaca mulatta	cationic pyrazole-sensitive isoenzyme, anodic pyrazole-sensitive isoenzyme and cathionic pyrazole-in sensitive isoenzyme	285580	-	-
Malus x domestica	-	669022	-	-
Mesocricetus auratus	-	285602	-	-
Mesocricetus auratus	3 major isoenzymes: TT-ADH, AA-ADH and BB-ADH	285650	-	-
Methylobacterium extorquens	-	669027	-	-
Meyerozyma guilliermondii	strain B10-05	285640	-	-
Meyerozyma guilliermondii B10-05	strain B10-05	285640	-	-
Mucor circinelloides	strain YR-1	667237	-	-
Mucor circinelloides YR-1	strain YR-1	667237	-	-
Mus musculus	-	655233, 667832, 668205, 697214, 699982	-	-
Mus musculus	class III enzyme	285564	-	-
Mus musculus	isoenzyme A2, B2 and C2	285603	-	-
Mus musculus	isozymes ADH1 and ADH4	655479	-	-
Mus musculus	low-activity isozyme ADH2	654730	Q9QYY9	Uniprot
Naja naja	-	285612	-	-
Najas marina	-	285562	-	-
Natronomonas pharaonis	-	686626	-	-
Neurospora crassa	-	659773	-	-
Neurospora crassa	FGSC2489	684614	-	-
Neurospora crassa	FGSC2489	684614	Q9P6C8	SwissProt
Neurospora crassa FGSC2489	FGSC2489	684614	-	-
Neurospora crassa FGSC2489	FGSC2489	684614	Q9P6C8	SwissProt
Oncorhynchus mykiss	-	285614	-	-
Oryctolagus cuniculus	-	285600, 285601	-	-
Oryza sativa	-	285561, 285635	-	-
Petroselinum crispum	-	285627	-	-
Picrophilus torridus	-	684620	Q6L0S1	SwissProt
Pisum sativum	-	285635	-	-
Pseudomonas aeruginosa	-	660650	-	-
Pseudomonas aeruginosa	PaADH	657302	-	-
Pseudomonas aeruginosa PaADH	PaADH	657302	-	-
Pseudomonas fluorescens	strain DSM 50106, stereoselective enzyme	654294	-	-
Pseudomonas putida	probable alcohol dehydrogenase; strain S-5	678779	Q76HN6	UniProt
Rana perezi	-	656168	-	-
Rattus norvegicus	-	285565, 285604, 668205, 684336	-	-
Rattus norvegicus	class IV enzyme	285605	-	-
Rattus norvegicus	isoenzyme 1, 2, 3 and 4	285606	-	-
Rhodococcus erythropolis	-	658321	-	-
Rhodococcus ruber	strain DSM44541	655082	-	-
Rhodococcus ruber DSM44541	strain DSM44541	655082	-	-
Saara hardwickii	-	285607	-	-
Saccharomyces carlsbergensis	strain Y379-50	697267	B6UQD0	UniProt
Saccharomyces carlsbergensis Y379-50	strain Y379-50	697267	B6UQD0	UniProt
Saccharomyces cerevisiae	-	285558, 285641, 285643, 285644, 285645, 285649, 654053, 655735, 655741, 667307, 668532, 669148, 685776, 687134, 687831, 688435, 688657, 688866, 689887, 695705, 696411, 697267, 697658	-	-
Saccharomyces cerevisiae	-	684586	P00331	Uniprot
Saccharomyces cerevisiae	-	690211, 697669, 699019	P00330	Uniprot
Saccharomyces cerevisiae	alcohol dehydrogenase IV	285642	-	-
Saccharomyces cerevisiae	isoenzyme I, II and III	285646	-	-
Saccharomyces cerevisiae	isozyme YADH-1, YADH-2, and YADH-3	655649	-	-
Saimiri sciureus	pyrazole-insensitive isoenzyme and pyrazole-sensitive isoenzyme	285579	-	-
Scaptodrosophila lebanonensis	-	285563, 285593, 285616, 657317	-	-
Schizosaccharomyces pombe	-	285646	-	-
Schizosaccharomyces pombe	precursor	684960	Q09669	SwissProt
Sporotrichum pulverulentum	-	285639	-	-
Sulfolobus solfataricus	-	285611, 285621, 285625, 677301, 678121, 678363, 680442, 682627, 682630	-	-
Sulfolobus solfataricus	-	654684, 679816, 681372, 697839	P39462	UniProt
Sulfolobus solfataricus	strain DSM 1617	680428, 681763	-	-
Sulfolobus solfataricus	strain DSM1617	678116	-	-
Sulfolobus solfataricus	strain Gtheta	679883	-	-
Sulfolobus solfataricus	strain P2	681629	Q9UXF1	UniProt
Sulfolobus solfataricus DSM1617	strain DSM1617	678116	-	-
Sulfolobus solfataricus Gtheta	strain Gtheta	679883	-	-
Sulfolobus sp.	strain RC3	680428	P50381	UniProt
Sulfolobus sp. RC3	strain RC3	680428	P50381	UniProt
Suncus murinus	-	285560	-	-
Thermoanaerobacter brockii	-	655735, 697669	-	-
Thermoanaerobacter ethanolicus	strain JW200	695536	Q0PH30	UniProt
Thermoanaerobacter ethanolicus JW200	strain JW200	695536	Q0PH30	UniProt
Thermomicrobium roseum	ATCC 27502	655262	-	-
Thermoplasma acidophilum	strain DSM 1728	700124	Q9HIM3	UniProt
Thermus sp.	recombinantly produced in Escherichia coli	684246	-	-
Thermus sp.	strain ATN1	695811	B2ZRE3	UniProt
Thermus sp. ATN1	strain ATN1	695811	B2ZRE3	UniProt
Thermus thermophilus	-	684583	-	-
Triticum aestivum	-	285635	-	-
Triticum monococcum	-	285633	-	-
Triticum turgidum	3 isoenzymes	285632	-	-
Vicia faba	-	285559	-	-
Vitis vinifera	-	687228	-	-
Zea mays	-	285631, 285635	-	-
Zea mays	3 non-allelic alcohol dehydrogenase isoenzymes	285630	-	-
Zea mays	wild-type enzyme Adh1-1S and mutant enzyme Adh1-1S1108	285652	-	-
Zygosaccharomyces rouxii	-	658565	-	-
Zymomonas mobilis	ADH I and ADH II	285623	-	-
Zymomonas mobilis	ATCC 29191	667340	-	-
Zymomonas mobilis	enzyme form ADH-I and ADH-II	285622	-	-

GENERAL INFORMATION	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY	LITERATURE
No entries in this field

SUBSTRATE	PRODUCT	REACTION DIAGRAM	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY/ Substrate	LITERATURE/ Substrate	COMMENTARY/ Product	LITERATURE/ Product	Reversibility r=reversible ir=irreversible ?=not specified
(-)-carvone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	1% activity compared to cyclohexanone	695811	-	-	?
(1S,3S)-3-methylcyclohexanol + NAD+	(rac)-3-methylcyclohexanone + NADH + H+		Thermus sp.	B2ZRE3	125% activity compared to cyclohexanol	695811	163% activity compared to cyclohexanone	-	r
(6S)-5,6-dihydro-6-methyl-4H-thieno[2,3b]thiopyran-4-one-7,7-dioxide + NADH + H+	(4S,6S)-5,6-dihydro-4-hydroxy-6-methyl-4H-thieno[2,3b]thiopyran-7,7-dioxide + NAD+		Neurospora crassa	-	-	659773	-	-	-
(E)-hex-2-en-1-ol + NAD+	(E)-hex-2-en-1-one + NADH		Mus musculus	-	-	285603	-	-	?
(E)-hex-2-en-1-ol + NAD+	(E)-hex-2-en-1-one + NADH		Camellia sinensis	-	43.2% of the activity with ethanol	285628	-	-	?
(R)-2-butanol + NAD+	2-butanone + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
(R)-2-butanol + NAD+	2-butanone + NADH + H+		Leifsonia sp.	-	50% of the activity with 2-propanol	667255	-	-	ir
(R)-2-butanol + NAD+	2-butanone + NADH + H+		Devosia riboflavina	-	55% of activity with N-benzyl-3-pyrrolidinol	688442	-	-	?
(R)-2-butanol + NAD+	(R)-2-butanone + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
(R)-2-butanol + NAD+	(R)-2-butanone + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
(R)-2-heptanol + NAD+	2-heptanone + NADH + H+		Leifsonia sp.	-	2469% of the activity with 2-propanol	667255	-	-	r
(R)-2-hexanol + NAD+	2-hexanone + NADH + H+		Leifsonia sp.	-	1906% of the activity with 2-propanol	667255	-	-	r
(R)-2-octanol + NAD+	2-octanone + NADH + H+		Equus caballus	-	-	285586	-	-	-
(R)-2-octanol + NAD+	2-octanone + NADH + H+		Leifsonia sp.	-	2406% of the activity with 2-propanol	667255	-	-	r
(R)-2-pentanol + NAD+	2-pentanone + NADH + H+		Equus caballus	-	-	285586	-	-	-
(R)-2-pentanol + NAD+	2-pentanone + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
(R)-2-pentanol + NAD+	2-pentanone + NADH + H+		Leifsonia sp.	-	75% of the activity with 2-propanol	667255	-	-	r
(R)-2-phenylpropanol + NAD+	(R)-2-phenylpropanal + NADH + H+		Brevibacterium sp.	-	63% of the activity with 2-phenylethanol	669540	-	-	?
(R)-3-methylcyclohexanone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	2% activity compared to cyclohexanone	695811	-	-	?
(R,S)-2-methylbutan-1-ol + NAD+	(R,S)-2-methyl-butan-1-one + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
(R,S)-2-methylbutan-1-ol + NAD+	(R,S)-2-methyl-butan-1-one + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
(S)-(+)-1-indanol + NAD+	indanone + NADH + H+		Thermus thermophilus	-	-	684583	-	-	?
(S)-1-phenyl-2-propanol + NAD+	phenylacetone + NADH + H+		Thermus sp.	B2ZRE3	-	695811	9% activity compared to cyclohexanone	-	r
(S)-2-butanol + NAD+	2-butanone + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
(S)-2-butanol + NAD+	2-butanone + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
(S)-2-butanol + NAD+	2-butanone + NADH + H+		Leifsonia sp.	-	275% of the activity with 2-propanol	667255	-	-	ir
(S)-2-butanol + NAD+	(S)-2-butanone + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
(S)-2-butanol + NAD+	(S)-2-butanone + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
(S)-2-heptanol + NAD+	2-heptanone + NADH + H+		Leifsonia sp.	-	331% of the activity with 2-propanol	667255	-	-	r
(S)-2-hexanol + NAD+	2-hexanone + NADH + H+		Leifsonia sp.	-	38% of the activity with 2-propanol	667255	-	-	r
(S)-2-methylbutan-1-ol + NAD+	(S)-2-methyl-butan-1-one + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
(S)-2-methylbutan-1-ol + NAD+	(S)-2-methyl-butan-1-one + NADH + H+		Scaptodrosophila lebanonensis	-	-	285616	-	-	-
(S)-2-methylbutan-1-ol + NAD+	(S)-2-methyl-butan-1-one + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
(S)-2-octanol + NAD+	2-octanone + NADH + H+		Equus caballus	-	-	285586	-	-	-
(S)-2-octanol + NAD+	2-octanone + NADH + H+		Leifsonia sp.	-	81% of the activity with 2-propanol	667255	-	-	r
(S)-2-pentanol + NAD+	2-pentanone + NADH + H+		Equus caballus	-	-	285586	-	-	-
(S)-2-pentanol + NAD+	2-pentanone + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
(S)-2-pentanol + NAD+	2-pentanone + NADH + H+		Leifsonia sp.	-	25% of the activity with 2-propanol	667255	-	-	r
(S)-2-phenylpropanol + NAD+	(S)-2-phenylpropanal + NADH + H+		Brevibacterium sp.	-	156% of the activity with 2-phenylethanol	669540	-	-	?
(S)-4-phenylbutan-2-ol + NAD+	benzylacetone + NADH + H+		Thermus sp.	B2ZRE3	-	695811	3% activity compared to cyclohexanone	-	r
(S)-heptan-2-ol + NAD+	2-heptanone + NADH + H+		Thermus sp.	B2ZRE3	-	695811	-	-	r
(S)-pentan-2-ol + NAD+	2-pentanone + NADH + H+		Thermus sp.	B2ZRE3	-	695811	-	-	r
(S)-perillylalcohol + NAD+	(S)-perillaldehyde + NADH + H+		Thermus sp.	B2ZRE3	52% activity compared to cyclohexanol	695811	-	-	?
(Z)-hex-2-en-1-ol + NAD+	(Z)-hex-2-en-1-one + NADH		Camellia sinensis	-	9.7% of the activity with ethanol	285628	-	-	?
1,1-dichloroacetone + NADH + H+	1,1-dichloropropan-2-ol + NADH		Leifsonia sp.	-	1078% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
1,2-butanediol + NAD+	?		Dipodascus capitatus	-	35% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
1,2-hexanediol + NAD+	?		Dipodascus capitatus	-	20% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
1,2-pentanediol + NAD+	?		Dipodascus capitatus	-	12% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
1,2-propanediol + NAD+	hydroxyacetone + NADH		Fragaria x ananassa	-	-	669027	-	-	?
1,2-propanediol + NAD+	hydroxyacetone + NADH + H+		Methylobacterium extorquens	-	-	669027	-	-	?
1,3-butanediol + NAD+	?		Dipodascus capitatus	-	39% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
1,3-propanediol + 2 NAD+ + H2O	? + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 45% of the activity with ethanol	712962	-	-	r
1,3-propanediol + 2 NAD+ + H2O	? + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 5% of the activity with 1-octanol	712962	-	-	r
1,3-propanediol + NAD+	? + NADH		Desulfovibrio gigas	-	7% of the activity with ethanol	285654	-	-	?
1-(4'-chlorophenyl)ethanol + NAD+	1-(4'-chlorophenyl)ethanone + NADH + H+		Thermus thermophilus	-	26% of the activity with (S)-(-)-1-phenylethanol	684583	-	-	?
1-(4-fluorophenyl)ethanol + NAD+	1-(4-fluorophenyl)ethanone + NADH + H+		Thermus thermophilus	-	45% of the activity with (S)-(-)-1-phenylethanol	684583	-	-	?
1-(p-tolyl)-ethanol + NAD+	1-(4-methyl phenyl)ethanone + NADH + H+		Thermus sp.	B2ZRE3	19% activity compared to cyclohexanol	695811	26% activity compared to cyclohexanone	-	?
1-butanol + 2 NAD+ + H2O	butanoic acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 45% of the activity with ethanol	712962	-	-	r
1-butanol + 2 NAD+ + H2O	butanoic acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 50% of the activity with 1-octanol	712962	-	-	r
1-butanol + NAD+	butanal + NADH		Fragaria x ananassa	-	-	669027	-	-	?
1-butanol + NAD+	butanal + NADH		Brevibacterium sp.	-	111% of the activity with 2-phenylethanol	669540	-	-	?
1-butanol + NAD+	butanal + NADH + H+		Methylobacterium extorquens	-	-	669027	-	-	?
1-butanol + NAD+	butanal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
1-butanol + NAD+	butanal + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
1-butanol + NAD+	butanal + NADH + H+		Geobacillus thermoglucosidasius	Q6RS93	-	699071	-	-	?
1-butanol + NAD+	butanal + NADH + H+		Pseudomonas putida	Q76HN6	30% activity compared to benzyl alcohol	678779	-	-	?
1-butanol + NAD+	butanal + NADH + H+		Natronomonas pharaonis	-	15.7% of the activity with ethanol	686626	-	-	?
1-butanol + NAD+	butanal + NADH + H+		Neurospora crassa	Q9P6C8	about 80% of activity with ethanol, ADH1	684614	-	-	?
1-butanol + NAD+	butanal + NADH + H+		Thermus sp.	B2ZRE3	142% activity compared to cyclohexanol	695811	-	-	r
1-butanol + NAD+	butanal + NADH + H+		Thermoplasma acidophilum	Q9HIM3	67.7% activity compared to ethanol	700124	-	-	?
1-decanol + NAD+	decanal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
1-decanol + NAD+	decanal + NADH + H+		Pseudomonas putida	Q76HN6	13% activity compared to benzyl alcohol	678779	-	-	?
1-dodecanol + NAD+	dodecanal + NADH		Brevibacterium sp.	-	68% of the activity with 2-phenylethanol	669540	-	-	?
1-heptanol + NAD+	heptanal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
1-heptanol + NAD+	heptanal + NADH + H+		Geobacillus thermoglucosidasius	Q6RS93	-	699071	-	-	?
1-heptanol + NAD+	heptanal + NADH + H+		Pseudomonas putida	Q76HN6	25% activity compared to benzyl alcohol	678779	-	-	?
1-heptanol + NAD+	heptanal + NADH + H+		Thermus sp.	B2ZRE3	80% activity compared to cyclohexanol	695811	-	-	r
1-heptanol + NAD+	heptanol + NADH + H+		Leifsonia sp.	-	56% of the activity with 2-propanol, in the reverse reaction 755% of the activity with phenyl trifluoromethyl ketone	667255	-	-	r
1-heptanol + NAD+	1-heptanal + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
1-hexanol + 2 NAD+ + H2O	hexanoic acid acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 55% of the activity with 1-octanol	712962	-	-	r
1-hexanol + 2 NAD+ + H2O	hexanoic acid acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 70% of the activity with ethanol	712962	-	-	r
1-hexanol + NAD+	hexanal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
1-hexanol + NAD+	hexanal + NADH + H+		Geobacillus thermoglucosidasius	Q6RS93	-	699071	-	-	?
1-hexanol + NAD+	hexanal + NADH + H+		Leifsonia sp.	-	44% of the activity with 2-propanol, in the reverse reaction 1029% of the activity with phenyl trifluoromethyl ketone	667255	-	-	r
1-hexanol + NAD+	hexanal + NADH + H+		Pseudomonas putida	Q76HN6	61% activity compared to benzyl alcohol	678779	-	-	?
1-hexanol + NAD+	hexanal + NADH + H+		Neurospora crassa	Q9P6C8	about 90% of activity with ethanol, ADH1	684614	-	-	?
1-hexanol + NAD+	hexanal + NADH + H+		Thermus sp.	B2ZRE3	109% activity compared to cyclohexanol	695811	-	-	r
1-hexanol + NAD+	hexanal + NADH + H+		Thermoplasma acidophilum	Q9HIM3	15.3% activity compared to ethanol	700124	-	-	?
1-hexanol + NAD+	?		Dipodascus capitatus	-	15% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
1-hexanol + NAD+	1-hexanal + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
1-hydroxy-2-butanone + NADH + H+	butane-1,2-diol + NAD+		Dipodascus capitatus	-	59% of the activity with N-benzyl-3-pyrrolidinone	687850	-	-	?
1-hydroxymethyl-6-methylpyrene + NAD+	1-formyl-6-methylpyrene + NADH + H+		Homo sapiens	P00326, P08319	-	701322	-	-	r
1-hydroxymethyl-8-methylpyrene + NAD+	1-formyl-8-methylpyrene + NADH + H+		Homo sapiens	P00326, P08319	-	701322	-	-	r
1-hydroxymethylpyrene + NAD+	1-formylpyrene + NADH + H+		Homo sapiens	P00326, P08319	-	701322	-	-	r
1-indanol + NAD+	1-indanone + NADH + H+		Thermus thermophilus	-	-	684583	-	-	?
1-indanol + NAD+	1-indanone + NADH + H+		Thermus sp.	B2ZRE3	-	695811	1% activity compared to cyclohexanone	-	r
1-nonanol + NAD+	nonanal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
1-nonanol + NAD+	nonanal + NADH + H+		Pseudomonas putida	Q76HN6	12% activity compared to benzyl alcohol	678779	-	-	?
1-octanol + 2 NAD+ + H2O	octanoic acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	best substrate	712962	-	-	r
1-octanol + 2 NAD+ + H2O	octanoic acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 30% of the activity with ethanol	712962	-	-	r
1-octanol + 2 NADP+ + H2O	octanoic acid + 2 NADPH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962	-	-	r
1-octanol + NAD+	octanal + NADH		Brevibacterium sp.	-	101% of the activity with 2-phenylethanol	669540	-	-	?
1-octanol + NAD+	octanal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
1-octanol + NAD+	octanal + NADH + H+		Geobacillus thermoglucosidasius	Q6RS93	-	699071	-	-	?
1-octanol + NAD+	octanal + NADH + H+		Leifsonia sp.	-	33% of the activity with 2-propanol, in the reverse reaction 435% of the activity with phenyl trifluoromethyl ketone	667255	-	-	r
1-octanol + NAD+	octanal + NADH + H+		Pseudomonas putida	Q76HN6	11% activity compared to benzyl alcohol	678779	-	-	?
1-octanol + NAD+	octanal + NADH + H+		Neurospora crassa	Q9P6C8	about 85% of activity with ethanol, ADH1	684614	-	-	?
1-octanol + NAD+	octanal + NADH + H+		Thermus sp.	B2ZRE3	57% activity compared to cyclohexanol	695811	-	-	r
1-octanol + NAD+	octanal + NADH + H+		Homo sapiens	P00326, P08319	substrate for isozyme ADH3	701322	-	-	r
1-octanol + NAD+	1-octanal + NADH + H+		Devosia riboflavina	-	6% of activity with N-benzyl-3-pyrrolidinol	688442	-	-	?
1-pentanol + NAD+	pentanal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
1-pentanol + NAD+	pentanal + NADH + H+		Geobacillus thermoglucosidasius	Q6RS93	-	699071	-	-	?
1-pentanol + NAD+	pentanal + NADH + H+		Pseudomonas putida	Q76HN6	152% activity compared to benzyl alcohol	678779	-	-	?
1-pentanol + NAD+	pentanal + NADH + H+		Neurospora crassa	Q9P6C8	about 85% of activity with ethanol, ADH1	684614	-	-	?
1-pentanol + NAD+	pentanal + NADH + H+		Thermus sp.	B2ZRE3	121% activity compared to cyclohexanol	695811	-	-	r
1-pentanol + NAD+	pentanal + NADH + H+		Thermoplasma acidophilum	Q9HIM3	19.1% activity compared to ethanol	700124	-	-	?
1-pentanol + NAD+	pentanal + NADH + H*		Dipodascus capitatus	-	8% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
1-pentanol + NAD+	1-pentanal + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
1-phenyl-1,2-ethanediol + NAD+	1-phenyl-2-propanone + NADH + H+		Thermus sp.	B2ZRE3	1% activity compared to cyclohexanol	695811	-	-	r
1-phenyl-1,2-propanedione + NADH + H+	?		Thermus thermophilus	-	activity is 1.46fold higher than with 2,2,2-trifluoroacetophenone	684583	-	-	?
1-phenyl-1-propanol + NAD+	1-phenyl-1-propanone + NADH + H+		Thermus thermophilus	-	59% of the activity with (S)-(-)-1-phenylethanol	684583	-	-	?
1-phenyl-1-propanol + NAD+	?		Dipodascus capitatus	-	31% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
1-phenyl-2-butanone + NADH + H+	1-phenylbutan-2-ol + NAD+		Leifsonia sp.	-	12% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
1-phenyl-2-butanone + NADH + H+	1-phenylbutan-2-ol + NAD+		Devosia riboflavina	-	1.5fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
1-phenyl-2-propanol + NAD+	1-phenyl-2-propanone + NADH + H+		Thermus thermophilus	-	16% of the activity with (S)-(-)-1-phenylethanol	684583	-	-	?
1-phenyl-2-propanol + NAD+	1-phenyl-2-propanone + NADH + H+		Thermus sp.	B2ZRE3	3% activity compared to cyclohexanol	695811	-	-	r
1-phenyl-2-propanone + NADH + H+	(S)-1-phenyl-2-propanol + NAD+		Rhodococcus erythropolis	-	-	658321	-	-	-
1-phenyl-3-butanone + NADH + H+	1-phenylbutan-3-ol + NAD+		Leifsonia sp.	-	353% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
1-phenylethanol + NAD+	1-phenylethanone + NADH		Picrophilus torridus	Q6L0S1	-	684620	-	-	?
1-phenylethanol + NAD+	1-phenylethanone + NADH		Brevibacterium sp.	-	46% of the activity with 2-phenylethanol	669540	-	-	?
1-phenylethanol + NAD+	1-phenylethanone + NADH + H+		Thermus sp.	B2ZRE3	3% activity compared to cyclohexanol	695811	-	-	r
1-phenylethanol + NAD+	acetophenone + NADH + H+		Thermus sp.	B2ZRE3	-	695811	1% activity compared to cyclohexanone	-	?
1-propanol + NAD+	propanal + NADH		Fragaria x ananassa	-	-	669027	-	-	?
1-propanol + NAD+	propanal + NADH + H+		Sulfolobus solfataricus	-	-	678116, 678121, 681763	-	-	?
1-propanol + NAD+	propanal + NADH + H+		Methylobacterium extorquens	-	-	669027	-	-	?
1-propanol + NAD+	propanal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
1-propanol + NAD+	propanal + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
1-propanol + NAD+	propanal + NADH + H+		Neurospora crassa	Q9P6C8	about 75% of activity with ethanol, ADH1	684614	-	-	?
1-propanol + NAD+	propanal + NADH + H+		Thermus sp.	B2ZRE3	153% activity compared to cyclohexanol	695811	-	-	r
11-cis-retinal + NADH + H+	11-cis-retinol + NAD+		Equus caballus	-	-	285584	-	-	?
11-cis-retinol + NAD+	11-cis-retinal + NADH		Mus musculus, Homo sapiens	-	-	655479	-	-	?
11-cis-retinol + NAD+	11-cis-retinal + NADH		Equus caballus	-	-	285648	-	285648	?
12-hydroxydodecanoate + NAD+	12-oxododecanoic acid + NADH		Homo sapiens	-	-	285566, 285569, 285571, 285608, 285651	-	-	?
12-hydroxydodecanoate + NAD+	12-oxododecanoic acid + NADH		Rattus norvegicus	-	-	285604	-	-	?
12-hydroxydodecanoate + NAD+	12-oxododecanoic acid + NADH		Mesocricetus auratus	-	-	285650	-	-	?
12-hydroxydodecanoate + NAD+	12-oxododecanoic acid + NADH		Coturnix coturnix	-	-	285615	-	-	?
12-hydroxydodecanoate + NAD+	12-oxododecanoic acid + NADH		Mesocricetus auratus	-	oxidized at pH 10, not oxidized at pH 7.5	285602	-	-	-
13-cis-retinal + NAD+	13-cis-retinol + NADH		Equus caballus	-	-	285584	-	-	?
13-cis-retinol + NAD+	13-cis-retinal + NADH		Equus caballus	-	-	285648	-	285648	?
13-cis-retinol + NAD+	13-cis-retinal + NADH		Mus musculus, Homo sapiens	-	no activity with isozyme ADH1	655479	-	-	?
16-hydroxyhexadecanoate + NAD+	16-oxohexadecanoic acid + NADH		Homo sapiens	-	-	285568, 285569	-	-	?
17beta-hydroxyetiocholan-3-one + NAD+	ethiocholan-3,17-dione + NADH		Homo sapiens	-	-	285571	-	-	?
2,2,2-trichloroethanol + NAD+	trichloroacetaldehyde + NADH + H+		Thermomicrobium roseum	-	-	655262	-	-	?
2,2,2-trifluoroacetophenone + NADH + H+	(R)-alpha-(trifluoromethyl)benzyl alcohol + NAD+		Thermus thermophilus	-	93% enantiomeric excess	684583	-	-	?
2,2-dichloroacetophenone + NADH + H+	2,2-dichloro-1-phenylethanol + NAD+		Thermus thermophilus	-	32% of the activity with 2,2,2-trifluoroacetophenone	684583	-	-	?
2,3'-dichloroacetophenone + NADH + H+	1-(2,3-dichlorophenyl)ethanol + NAD+		Leifsonia sp.	-	67% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
2,3-butanediol + H2O	?		Picrophilus torridus	Q6L0S1	-	684620	-	-	?
2,3-butanediol + NAD+	?		Dipodascus capitatus	-	83% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
2,3-butanedione + NADH + H+	?		Dipodascus capitatus	-	activity is 1.6fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
2,3-pentanedione + NADH	? + NADH		Petroselinum crispum	-	5.5% of the activity with acetaldehyde	285627	-	-	?
2,4-pentanediol + NAD+	?		Dipodascus capitatus	-	21% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
2,4-pentanediol + NAD+	?		Thermus sp.	B2ZRE3	4% activity compared to cyclohexanol	695811	-	-	?
2-acetylpyrrole + NADH + H+	1-(1H-pyrrol-2-yl)ethanol + NAD+		Devosia riboflavina	-	70% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
2-aminoethanol + NAD+	?		Picrophilus torridus	Q6L0S1	-	684620	-	-	?
2-butanol + NAD+	2-butanone + NADH + H+		Corynebacterium glutamicum R	-	-	684612	-	-	?
2-butanol + NAD+	2-butanone + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	weak activity	668532	-	-	r
2-butanol + NAD+	2-butanone + NADH + H+		Neurospora crassa	Q9P6C8	about 25% of activity with ethanol, ADH1	684614	-	-	?
2-butanol + NAD+	2-butanone + NADH + H+		Dipodascus capitatus	-	activity is 3.7fold higher than with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	r
2-butanol + NAD+	2-butanone + NADH + H+		Thermus sp.	B2ZRE3	39% activity compared to cyclohexanol	695811	4% activity compared to cyclohexanone	-	r
2-butanone + NADH + H+	2-butanol + NAD+		Dipodascus capitatus	-	40% of the activity with N-benzyl-3-pyrrolidinone	687850	-	-	r
2-butanone + NADH + H+	butan-2-ol + NAD+		Devosia riboflavina	-	2.8fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
2-butanone + NADPH + H+	butan-2-ol + NADP+		Candida parapsilosis	B2KJ46	12.1% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
2-butene-1-ol + NAD+	? + NADH		Rattus norvegicus	-	-	285604	-	-	?
2-butene-1-ol + NAD+	? + NADH		Zea mays	-	-	285630	-	-	?
2-chlorocyclohexanone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	3% activity compared to cyclohexanone	695811	-	-	?
2-decalone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	28% activity compared to cyclohexanone	695811	-	-	?
2-decanol + NAD+	2-decanone + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	weak activity	668532	-	-	r
2-deoxy-D-ribose + NAD+	? + NADH		Homo sapiens	-	-	285569	-	-	?
2-ethoxyethanol + NAD+	2-ethoxyacetaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
2-ethylhexan-1-ol + NAD+	2-ethylhexanal + NADH		Sporotrichum pulverulentum	-	weak activity	285639	-	-	?
2-heptanol + NAD+	2-heptanone + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	weak activity	668532	-	-	r
2-heptanol + NAD+	2-heptanone + NADH + H+		Thermus sp.	B2ZRE3	63% activity compared to cyclohexanol	695811	5% activity compared to cyclohexanone	-	r
2-heptanone + NADH + H+	(R)-2-heptanol + NAD+		Leifsonia sp.	-	229% of the activity with phenyl trifluoromethyl ketone	667255	99% enantiomeric excess	-	?
2-heptanone + NADPH + H+	heptan-2-ol + NADP+		Candida parapsilosis	B2KJ46	6.8% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
2-hexanol + NAD+	2-hexanone + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	weak activity	668532	-	-	r
2-hexanol + NAD+	2-hexanone + NADH + H+		Thermus sp.	B2ZRE3	64% activity compared to cyclohexanol	695811	4% activity compared to cyclohexanone	-	r
2-hexanone + NADH + H+	?		Dipodascus capitatus	-	activity is 1.6fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
2-hexanone + NADH + H+	hexan-2-ol + NAD+		Devosia riboflavina	-	50.4fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
2-hexanone + NADPH + H+	hexan-2-ol + NADP+		Candida parapsilosis	B2KJ46	5.9% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
2-hexcanol + NAD+	2-hexanone + NADH + H+		Dipodascus capitatus	-	activity is 11.2fold higher than with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
2-hydroxyacetophenone + NADH + H+	(S)-1-phenyl-1,2-ethanediol + NAD+		Candida parapsilosis	B2KJ46	2.4% of the activity with NADPH	684556	-	-	?
2-hydroxyacetophenone + NADPH + H+	(S)-1-phenyl-1,2-ethanediol + NADP+		Candida parapsilosis	B2KJ46	-	684556	-	-	?
2-hydroxymethylpyrene + NAD+	2-formylpyrene + NADH + H+		Homo sapiens	P00326, P08319	-	701322	-	-	r
2-mercaptoethanol + NAD+	?		Thermus sp.	B2ZRE3	11% activity compared to cyclohexanol	695811	-	-	?
2-methoxybenzaldehyde + NADH + H+	2-methoxybenzylalcohol + NAD+		Thermus thermophilus	-	13% of the activity with 2,2,2-trifluoroacetophenone	684583	-	-	?
2-methoxybenzyl alcohol + NAD+	2-methoxybenzaldehyde + NADH + H+		Thermus thermophilus	-	25% of the activity with (S)-(-)-1-phenylethanol	684583	-	-	?
2-methyl-2,4-pentanediol + NAD+	?		Thermus sp.	B2ZRE3	1% activity compared to cyclohexanol	695811	-	-	?
2-methylbutan-1-ol + NAD+	? + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
2-methylbutyraldehyde + NADH + H+	2-methylbutanol + NAD+		Cucumis melo	-	1.4% of the activity with acetaldehyde	670572	-	-	?
2-methylcyclohexanone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	46% activity compared to cyclohexanone	695811	-	-	?
2-methylpropan-1-ol + NAD+	2-methyl-propan-1-one + NADH		Zea mays	-	-	285652	-	-	?
2-methylpropan-1-ol + NAD+	2-methyl-propan-1-one + NADH		Triticum monococcum	-	-	285633	-	-	-
2-methylpropan-1-ol + NAD+	2-methyl-propan-1-one + NADH		Sporotrichum pulverulentum	-	-	285639	-	-	?
2-methylpropan-1-ol + NAD+	2-methyl-propan-1-one + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
2-methylpropan-1-ol + NAD+	2-methyl-propan-1-one + NADH		Triticum turgidum	-	-	285632	-	-	-
2-methylpropan-1-ol + NAD+	2-methyl-propan-1-one + NADH		Zea mays	-	weak activity	285630	-	-	?
2-methylpropan-1-ol + NAD+	2-methyl-propan-1-one + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
2-methylpropan-1-ol + NAD+	2-methyl-propan-1-one + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
2-methylpropionaldehyde + NADH + H+	2-methylpropanal + NAD+		Cucumis melo	-	3.3% of the activity with acetaldehyde	670572	-	-	?
2-nitrobenzaldehyde + NADH + H+	2-nitrophenylbenzyl alcohol + NAD+		Devosia riboflavina	-	33% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
2-nonanol + NAD+	2-nonanone + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	weak activity	668532	-	-	r
2-octanol + NAD+	2-octanone + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	weak activity	668532	-	-	r
2-octanol + NAD+	2-octanone + NADH + H+		Thermus sp.	B2ZRE3	43% activity compared to cyclohexanol	695811	4% activity compared to cyclohexanone	-	r
2-octanone + NADPH + H+	octan-2-ol + NADP+		Candida parapsilosis	B2KJ46	11.9% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
2-oxo-butyric acid + NADH + H+	2-hydroxybutyric acid + NAD+		Devosia riboflavina	-	15% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
2-pentanol + NAD+	2-pentanone + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	weak activity	668532	-	-	r
2-pentanol + NAD+	2-pentanone + NADH + H+		Devosia riboflavina	-	45% of activity with N-benzyl-3-pyrrolidinol	688442	-	-	?
2-pentanol + NAD+	2-pentanone + NADH + H+		Dipodascus capitatus	-	activity is 9fold higher than with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
2-pentanol + NAD+	2-pentanone + NADH + H+		Thermoplasma acidophilum	Q9HIM3	5.7% activity compared to ethanol	700124	-	-	?
2-pentanone + NAD+	2-pentanal + NADH + H+		Thermus sp.	B2ZRE3	6% activity compared to cyclohexanol	695811	-	-	r
2-pentanone + NADH	pentan-2-ol + NAD+		Equus caballus	-	-	285586	-	285586	r
2-pentanone + NADPH + H+	pentan-2-ol + NADP+		Candida parapsilosis	B2KJ46	11.9% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
2-phenylcyclohexanone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	2% activity compared to cyclohexanone	695811	-	-	?
2-phenylethanol + NAD+	phenylacetaldehyde + NADH + H+		Brevibacterium sp.	-	-	669540	-	-	r
2-phenylethanol + NAD+	2-phenylethanone + NADH + H+		Thermus sp.	B2ZRE3	57% activity compared to cyclohexanol	695811	-	-	r
2-propanol + NAD(P)+	acetone + NAD(P)H		Saccharomyces cerevisiae, Thermoanaerobacter brockii	-	-	655735	-	-	?
2-propanol + NAD+	acetone + NADH		Saccharomyces cerevisiae	-	-	655741	-	-	?
2-propanol + NAD+	acetone + NADH + H+		Thermus thermophilus	-	-	684583	-	-	?
2-propanol + NAD+	acetone + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
2-propanol + NAD+	acetone + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
2-propanol + NAD+	acetone + NADH + H+		Leifsonia sp.	-	-	667255	-	-	ir
2-propanol + NAD+	acetone + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
2-propanol + NAD+	acetone + NADH + H+		Neurospora crassa	Q9P6C8	about 50% of activity with ethanol, ADH1	684614	-	-	?
2-propanol + NAD+	2-propanone + NADH		Fragaria x ananassa	-	-	669027	-	-	?
2-propanol + NAD+	2-propanone + NADH		Picrophilus torridus	Q6L0S1	-	684620	-	-	?
2-propanol + NAD+	2-propanone + NADH		Brevibacterium sp.	-	54% of the activity with 2-phenylethanol	669540	-	-	?
2-propanol + NAD+	2-propanone + NADH + H+		Sulfolobus solfataricus	-	-	678116, 681763	-	-	?
2-propanol + NAD+	2-propanone + NADH + H+		Methylobacterium extorquens	-	-	669027	-	-	?
2-propanol + NAD+	2-propanone + NADH + H+		Geobacillus thermoglucosidasius	Q6RS93	-	699071	-	-	?
2-propanol + NAD+	2-propanone + NADH + H+		Dipodascus capitatus	-	activity is 3.1fold higher than with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
2-propanol + NAD+	2-propanone + NADH + H+		Thermus sp.	B2ZRE3	6% activity compared to cyclohexanol	695811	-	-	r
2-propanol + NAD+	2-propanone + NADH + H+		Thermoplasma acidophilum	Q9HIM3	73.5% activity compared to ethanol	700124	-	-	?
2-propanol + NAD+	propanone + NADH + H+		Corynebacterium glutamicum R	-	-	684612	-	-	r
3',4'dimethoxyphenylacetone + NADH + H+	1-(3,4-dimethoxyphenyl)ethanol + NAD+		Leifsonia sp.	-	24% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
3'-bromoacetophenone + NADH + H+	1-(3-bromophenyl)ethanol + NAD+		Leifsonia sp.	-	151% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
3'-chloroacetophenone + NADH + H+	1-(3-chlorophenyl)ethanol + NAD+		Leifsonia sp.	-	70% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
3'-methoxyacetophenone + NADH + H+	1-(3-methoxyphenyl)ethanol + NAD+		Leifsonia sp.	-	51% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
3,3,5-trimethylcyclohexanone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	2% activity compared to cyclohexanone	695811	-	-	?
3,4-dihydro-retinol + NAD+	3,4-dihydro-retinal		Homo sapiens	-	-	654370	-	-	r
3,4-dimethylbenzyl alcohol + NAD+	3,4-dimethylbenzaldehyde + NADH + H+		Thermus sp.	B2ZRE3	45% activity compared to cyclohexanol	695811	-	-	r
3,4-hexanedione + NADH + H+	?		Dipodascus capitatus	-	77% of the activity with N-benzyl-3-pyrrolidinone	687850	-	-	?
3,4-methylenedioxyphenyl acetone + NADH	(S)-(3,4-methylenedioxyphenyl)-2-propanol + NAD+ + H+		Zygosaccharomyces rouxii	-	-	658565	-	-	-
3,5-dimethylcyclohexanol + NAD+	3,5-dimethylcyclohexanone + NADH + H+		Thermus sp.	B2ZRE3	1% activity compared to cyclohexanol	695811	-	-	r
3-acetylpyridine + NADH + H+	1-pyridin-3-ylethanol + NAD+		Devosia riboflavina	-	7.9fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
3-aminobenzyl alcohol + NAD+	3-aminobenzaldehyde + NADH + H+		Thermus sp.	B2ZRE3	8% activity compared to cyclohexanol	695811	-	-	r
3-bromobenzyl alcohol + NAD+	3-bromobenzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	678116	-	-	?
3-bromobenzylalcohol + NAD+	3-bromobenzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	681763	-	-	?
3-butene-1-ol + NAD+	? + NADH		Zea mays	-	-	285630	-	-	?
3-chloro-2-butanone + NADH + H+	3-chlorobutan-2-ol + NAD+		Leifsonia sp.	-	151% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
3-heptanol + NAD+	3-heptanone + NADH + H+		Leifsonia sp.	-	93% of the activity with 2-propanol	667255	-	-	r
3-methoxybenzaldehyde + NADH + H+	3-methoxybenzylalcohol + NAD+		Thermus thermophilus	-	14% of the activity with 2,2,2-trifluoroacetophenone	684583	-	-	?
3-methoxybenzyl alcohol + NAD+	3-methoxybenzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	678116	-	-	?
3-methoxybenzyl alcohol + NAD+	3-methoxybenzaldehyde + NADH + H+		Thermus thermophilus	-	13% of the activity with (S)-(-)-1-phenylethanol	684583	-	-	?
3-methoxybenzylalcohol + NAD+	3-methoxybenzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	681763	-	-	?
3-methyl-1-butanol + NAD+	? + NADH		Equus caballus	-	-	285647	-	-	?
3-methyl-2-cyclohexenone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	1% activity compared to cyclohexanone	695811	-	-	?
3-methylbutan-1-ol + NAD+	3-methyl-butan-1-one + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
3-methylbutan-1-ol + NAD+	3-methyl-butan-1-one + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
3-methylbutan-2-ol + NAD+	3-methylbutan-2-one + NADH		Scaptodrosophila lebanonensis	-	R-(-)-3-methylbutan-2-ol and S-(+)-3-methylbutan-2-ol	285616	-	-	?
3-methylbutan-2-one + NADH	3-methylbutan-2-ol + NAD+		Sulfolobus solfataricus	-	-	285621	-	-	?
3-methylbutan-2-one + NADH + H+	3-methylbutan-2-ol + NAD+		Sulfolobus solfataricus	-	-	678363	-	-	?
3-methylbutanol + NAD+	? + NADH		Triticum monococcum	-	-	285633	-	-	?
3-methylbutanol + NAD+	? + NADH		Triticum turgidum	-	-	285632	-	-	?
3-methylbutanol + NAD+	3-methylbutanone + NADH + H+		Thermus sp.	B2ZRE3	133% activity compared to cyclohexanol	695811	-	-	r
3-methylbutyraldehyde + NADH + H+	3-methylbutanol + NAD+		Cucumis melo	-	2.9% of the activity with acetaldehyde	670572	-	-	?
3-methylcyclohexanol + NAD+	3-methylcyclohexanone + NADH		Sulfolobus solfataricus	-	-	285621	-	-	r
3-methylcyclohexanone + NADH	3-methylcyclohexanol + NAD+		Sulfolobus solfataricus	-	-	285621	-	-	r
3-methylphenylethyl alcohol + NAD+	?		Thermus sp.	B2ZRE3	64% activity compared to cyclohexanol	695811	-	-	?
3-oxo-5beta-androstan-17beta-ol + NADH	3beta,17beta-dihydroxy-5beta-androstane + NAD+		Rattus norvegicus	-	-	285604	-	-	?
3-oxo-5beta-androstan-17beta-ol + NADH	3beta,17beta-dihydroxy-5beta-androstane + NAD+		Equus caballus	-	-	285583, 285597	-	-	?
3-pentanol + NAD+	3-pentanone + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
3-pentanol + NAD+	3-pentanone + NADH + H+		Thermus sp.	B2ZRE3	2% activity compared to cyclohexanol	695811	2% activity compared to cyclohexanone	-	r
3-pentanone + NADH	pentan-3-ol + NAD+		Equus caballus	-	-	285586	-	285586	r
3-pentanone + NADPH + H+	pentan-3-ol + NADP+		Candida parapsilosis	B2KJ46	7.1% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
3-penten-2-one + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	2% activity compared to cyclohexanone	695811	-	-	?
3-phenyl-1-propanol + NAD+	3-phenyl-1-propanone + NADH		Homo sapiens	-	-	285569	-	-	-
3-phenyl-1-propanol + NAD+	3-phenyl-1-propanone + NADH		Homo sapiens	-	-	285568	-	-	?
3-phenyl-2-propen-1-ol + NAD+	? + NADH		Zea mays	-	-	285630	-	-	?
3-phenylpropanol + NAD+	3-phenylpropanal + NADH + H+		Brevibacterium sp.	-	135% of the activity with 2-phenylethanol	669540	-	-	?
3-phenylpropionaldehyde + NADH	3-phenylpropan-1-ol + NAD+		Leifsonia sp.	-	1218% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
3-phenylpropionaldehyde + NADH + H+	3-phenylpropanol + NAD+		Devosia riboflavina	-	6.9fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
3-pyridylcarbinol + NAD+	pyridine-3-carbaldehyde + NADH		Homo sapiens	-	-	285573	-	-	?
3beta,12alpha-dihydroxy-5beta-cholanoic acid + NAD+	? + NADH		Rattus norvegicus	-	-	285606	-	-	?
3beta,17beta-dihydroxy-5beta-androstane + NAD+	5beta-androstan-3,17dione + NADH		Equus caballus	-	-	285583	-	-	?
3beta,7alpha,12alpha-trihydroxy-5beta-cholanoic acid + NAD+	? + NADH		Rattus norvegicus	-	-	285606	-	-	?
3beta,7alpha-dihydroxy-5beta-cholanoic acid + NAD+	? + NADH		Rattus norvegicus	-	-	285606	-	-	?
3beta-hxdroxy-5alpha-cholanoate + NAD+	3-oxo-5alpha-cholanoate + NADH		Equus caballus	-	-	285583	-	-	?
3beta-hydroxy-5beta-androstan-17-one + NAD+	5beta-androstan-3,17-dione + NADH		Rattus norvegicus	-	-	285606	-	-	-
3beta-hydroxy-5beta-androstan-17-one + NAD+	5beta-androstan-3,17-dione + NADH		Equus caballus	-	-	285583	-	-	?
3beta-hydroxy-5beta-androstan-17-one + NAD+	5beta-androstan-3,17-dione + NADH		Mesocricetus auratus	-	catalyzed by isoenzyme BB-ADH, no activity with isoenzyme AA-ADH and TT-ADH	285650	-	-	?
3beta-hydroxy-5beta-cholanoate + NAD+	3-oxo-5beta-cholanoate + NADH		Equus caballus	-	-	285583	-	-	?
4'-bromoacetophenone + NADH + H+	1-(4-bromophenyl)ethanol + NAD+		Leifsonia sp.	-	77% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
4'-chloroacetophenone + NADH + H+	1-(4-chlorophenyl)ethanol + NAD+		Leifsonia sp.	-	60% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
4-acetylpyridine + NADH + H+	1-pyridin-4-ylethanol + NAD+		Devosia riboflavina	-	64.5fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
4-bromobenzyl alcohol + NAD+	4-bromobenzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	678116	-	-	?
4-bromobenzylalcohol + NAD+	4-bromobenzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	681763	-	-	?
4-carboxybenzaldehyde + NADH + H+	4-carboxybenzyl alcohol + NAD+		Sulfolobus solfataricus	-	-	678116	-	-	?
4-carboxybenzaldehyde + NADH + H+	4-carboxybenzylalcohol + NAD+		Sulfolobus solfataricus	-	-	681763	-	-	?
4-chlorobutyrophenone + NADH + H+	1-(4-chlorophenyl)butan-1-ol + NAD+		Thermus thermophilus	-	10% of the activity with 2,2,2-trifluoroacetophenone	684583	-	-	?
4-ethylcyclohexanol + NAD+	4-ethylcyclohexanone + NADH + H+		Thermus sp.	B2ZRE3	60% activity compared to cyclohexanol	695811	-	-	r
4-ethylcyclohexanone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	22% activity compared to cyclohexanone	695811	-	-	?
4-hydroxy-2-butanone + NADH + H+	2,4-dihydroxybutane + NAD+		Leifsonia sp.	-	26% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
4-hydroxy-retinol + NAD+	4-oxo-retinal + NADH		Homo sapiens	-	-	654370	-	-	r
4-hydroxymethylpyrene + NAD+	4-formylpyrene + NADH + H+		Homo sapiens	P00326, P08319	-	701322	-	-	r
4-hydroxynonenal + NADH + H+	4-hydroxynonenol + NAD+		Homo sapiens	-	substrate of isozyme ADH4	691867	-	-	r
4-methoxy-1-naphthaldehyde + NAD+	4-methoxy-1-naphthyl alcohol + NADH + H+		Homo sapiens	-	substrate for class I ADH	686331	-	-	?
4-methoxy-1-naphthaldehyde + NADH + H+	4-methoxy-1-naphthyl alcohol + NAD+		Homo sapiens	-	substrate for class I ADH	697802	-	-	r
4-methoxybenzaldehyde + NADH + H+	4-methoxybenzylalcohol + NAD+		Thermus thermophilus	-	13% of the activity with 2,2,2-trifluoroacetophenone	684583	-	-	?
4-methoxybenzyl alcohol + NAD+	4-methoxybenzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	678116, 678121, 697839	-	-	r
4-methoxybenzyl alcohol + NAD+	4-methoxybenzaldehyde + NADH + H+		Thermus thermophilus	-	99% of the activity with (S)-(-)-1-phenylethanol	684583	-	-	?
4-methoxybenzylalcohol + NAD+	4-methoxybenzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	681763	-	-	r
4-methyl-1-pentanol + NAD+	4-methyl-1-pentanal + NADH		Equus caballus	-	-	285647	-	-	-
4-methyl-1-pentanol + NAD+	4-methyl-1-pentanal + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
4-methylcyclohexanol + NAD+	4-methylcyclohexanone + NADH + H+		Thermus sp.	B2ZRE3	56% activity compared to cyclohexanol	695811	-	-	r
4-methylcyclohexanone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	25% activity compared to cyclohexanone	695811	-	-	?
4-nitrobenzaldehyde + NADH + H+	4-nitrobenzyl alcohol + NAD+		Sulfolobus solfataricus	-	-	678116	-	-	?
4-nitrobenzaldehyde + NADH + H+	4-nitrobenzylalcohol + NAD+		Sulfolobus solfataricus	-	-	681763	-	-	?
4-nitrobenzyl alcohol + NAD+	4-nitrobenzaldehyde + NADH + H+		Pseudomonas putida	Q76HN6	94% activity compared to benzyl alcohol	678779	-	-	?
5-hydroxymethylfurfural + NADH + H+	?		Saccharomyces cerevisiae	P00330	mutant enzyme S109P/L116S/Y294C	690211	-	-	?
5alpha-androstan-17beta-ol-3-one + NADH + H+	3beta,17beta-dihydroxy-5alpha-androstan + NAD+		Homo sapiens	-	-	655206	-	-	-
5alpha-androstan-17beta-ol-3-one + NADH + H+	3beta,17beta-dihydroxy-5alpha-androstan + NAD+		Rattus norvegicus	-	-	285606	-	-	?
5alpha-pregnan-3beta-ol-20-one + NAD+	5alpha-pregnan-3,20-dione + NADH		Homo sapiens	-	low activity	655206	-	-	?
5beta-androstan-17beta-ol-3-one + NAD+	5beta-androstan-3,17-dione + NADH		Equus caballus	-	-	655206	-	-	?
5beta-androstan-17beta-ol-3-one + NAD+	5beta-androstan-3,17-dione + NADH		Homo sapiens	-	low activity	655206	-	-	?
5beta-androstan-3beta-ol-17-one + NAD+	5beta-androstan-3,17-dione + NADH		Homo sapiens, Equus caballus	-	-	655206	-	-	?
5beta-cholanic acid-3-one + NAD+	5beta-cholanic acid-3-ol + NAD+		Equus caballus	-	-	655206	-	-	?
5beta-cholanic acid-3-one + NADH	5beta-cholanic acid-3-ol + NAD+		Homo sapiens	-	low activity	655206	-	-	?
5beta-pregnan-21-ol-3,20-dione hemisuccinate + NADH	5beta-pregnan-3,20,21-trione hemisuccinate + NADH		Equus caballus	-	-	285597	-	-	?
5beta-pregnan-3,20-dione + NADH	?		Homo sapiens	-	-	655206	-	-	?
5beta-pregnan-3beta-ol-20-one + NAD+	5beta-pregnan-3,20-dione + NADH		Homo sapiens	-	-	655206	-	-	?
6-benzyloxy-3,5-dioxo-hexanoic acid ethyl ester + NADH + H+	(3R,5S)-6-benzyloxy-3,5-dihydroxy-hexanoic acid ethyl ester + NAD+		Acinetobacter calcoaceticus	-	-	659674	-	-	-
6-methoxy-2-naphthaldehyde + NAD+	6-methoxy-2-naphthyl alcohol + NADH + H+		Homo sapiens	-	substrate for class II ADH	686331	-	-	?
6-methoxy-2-naphthaldehyde + NADH + H+	6-methoxy-2-naphthyl alcohol + NAD+		Homo sapiens	-	substrate for class II ADH	697802	-	-	r
7-cis-retinol + NAD+	7-cis-retinal + NADH		Mus musculus, Homo sapiens	-	-	655479	-	-	?
9-cis-retinol + NAD+	9-cis-retinal + NADH		Mus musculus, Homo sapiens	-	-	655479	-	-	?
9-cis-retinol + NAD+	9-cis-retinal + NADH		Equus caballus	-	-	285648	-	285648	?
a primary alcohol + NAD+	an aldehyde + NADH + H+		Mus musculus	-	ADH3 is involved in multiple cellular pathways, as diverse as formaldehyde detoxification, retinoid metabolism and NO homeostasis, ADH3 is considered to play only a minor role in hepatic alcohol metabolism because ethanol concentrations rarely exceed 50 mM	697214	-	-	?
acetaldehyde + NADH + H+	ethanol + NAD+		Drosophila melanogaster	-	-	285598	-	285598	r
acetaldehyde + NADH + H+	ethanol + NAD+		Rattus norvegicus	-	-	285604	-	-	-
acetaldehyde + NADH + H+	ethanol + NAD+		Rattus norvegicus	-	-	285606	-	-	r
acetaldehyde + NADH + H+	ethanol + NAD+		Saccharomyces cerevisiae	-	-	285645	-	285645	r
acetaldehyde + NADH + H+	ethanol + NAD+		Emericella nidulans	-	-	285636	-	-	r
acetaldehyde + NADH + H+	ethanol + NAD+		Entamoeba histolytica	-	-	655804	-	-	?
acetaldehyde + NADH + H+	ethanol + NAD+		Equus caballus	-	-	285583	-	285583	r
acetaldehyde + NADH + H+	ethanol + NAD+		Equus caballus	-	-	285596	-	285596	r
acetaldehyde + NADH + H+	ethanol + NAD+		Equus caballus	-	-	285597	-	285597	r
acetaldehyde + NADH + H+	ethanol + NAD+		Zymomonas mobilis	-	-	285623	-	-	r
acetaldehyde + NADH + H+	ethanol + NAD+		Macaca mulatta	-	-	285580	-	285580	r
acetaldehyde + NADH + H+	ethanol + NAD+		Oryza sativa	-	-	285561	-	285561	r
acetaldehyde + NADH + H+	ethanol + NAD+		Candida sp.	-	-	285637	-	285637	-
acetaldehyde + NADH + H+	ethanol + NAD+		Cucumis melo	-	-	670572	-	-	r
acetaldehyde + NADH + H+	ethanol + NAD+		Malus x domestica	-	-	669022	-	-	?
acetaldehyde + NADH + H+	ethanol + NAD+		Sporotrichum pulverulentum	-	-	285639	-	285639	r
acetaldehyde + NADH + H+	ethanol + NAD+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962	-	-	r
acetaldehyde + NADH + H+	ethanol + NAD+		Desulfovibrio gigas	-	the reduction of acetaldehyde is 4.9fold faster than the oxidation of ethanol	285654	-	-	r
acetaldehyde + NADH + H+	ethanol + NAD+		Mus musculus	-	reduced by isoenzyme A2 and C2, no activity with isoenzyme B2	285603	-	-	-
acetaldehyde + NADH + H+	ethanol + NAD+		Vicia faba	-	reduced at the highest rate of all aldehydes tested	285559	-	285559	-
acetaldehyde + NADH + H+	ethanol + NAD+		Saccharomyces cerevisiae	-	cells with an extra copy of ADH1 display chronological life-span extension. Antioxidant enzymes are induced in 2xADH1 cells. Strains carrying an extra ADH1 copy show extended replicative life span and increased Sir2p activity	688866	-	-	?
acetaldehyde + NADH + H+	ethanol + NAD+		Saccharomyces cerevisiae	P00330	mutant enzyme S109P/L116S/Y294C	690211	-	-	?
acetaldehyde + NADH + H+	ethanol + NAD+ + H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962	-	-	r
acetaldehyde + NADPH + H+	ethanol + NADP+		Cucumis melo	-	16% of the activity with NADH	670572	-	-	r
acetone + NAD+ + H2O	? + NADH + H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 5% of the activity with 1-octanol	712962	-	-	r
acetone + NADH	isopropanol + NAD+		Equus caballus	-	-	285586	-	285586	r
acetone + NADH	isopropanol + NAD+		Sulfolobus solfataricus	-	-	285621	-	285621	r
acetone + NADH + H+	propan-2-ol + NAD+		Devosia riboflavina	-	1.9fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
acetone + NADPH + H+	propan-2-ol + NADP+		Candida parapsilosis	B2KJ46	14.7% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
acetophenone + NADH	(R)-alpha-phenyl ethanol + NAD+		Pseudomonas fluorescens	-	the enzyme exhibits high stereoselectivity in the desymmetrization of the prochiral ketone acetophenone, producing optically pure (R)-alpha-phenyl ethanol at high conversion	654294	-	-	?
acetophenone + NADH + H+	(R)-1-phenylethanol + NAD+		Leifsonia sp.	-	6% of the activity with phenyl trifluoromethyl ketone, in the reverse reaction 87% of the activity with 2-propanol	667255	99% enantiomeric excess	-	?
acetophenone + NADH + H+	1-phenylethanol + NAD+		Devosia riboflavina	-	1.8fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
acetophenone + NADH + H+	1-phenylethanol + NAD+		Dipodascus capitatus	-	40% of the activity with N-benzyl-3-pyrrolidinone	687850	-	-	?
acetophenone + NADH + H+	(S)-(-)-1-phenylethanol + NAD+		Thermus thermophilus	-	more than 99% enantiomeric excess	684583	-	-	r
acetophenone + NADPH + H+	1-phenylethanol + NADP+		Candida parapsilosis	B2KJ46	5.1% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
acetylacetone + NADH + H+	?		Dipodascus capitatus	-	63% of the activity with N-benzyl-3-pyrrolidinone	687850	-	-	?
acetylacetone + NADH + H+	acetophenone + NADH + H+		Thermus sp.	B2ZRE3	1% activity compared to cyclohexanone	695811	1% activity compared to cyclohexanone	-	r
alcohol + NAD+	aldehyde or ketone + NADH		Rhodococcus ruber	-	medium chain sec-alcohols or (omega-1)-ketones, no activity with primary alcohols or aldehydes	655082	-	-	r
all-trans-retinal + NADH + H+	all-trans-retinol + NAD+		Equus caballus	-	-	285648	-	-	?
all-trans-retinol + NAD+	all-trans-retinal + NADH		Mus musculus	-	-	655479, 697214	-	-	?
all-trans-retinol + NAD+	all-trans-retinal + NADH		Homo sapiens	-	-	285608, 655479	-	-	?
all-trans-retinol + NAD+	all-trans-retinal + NADH		Homo sapiens	-	-	654370, 656058	-	-	r
all-trans-retinol + NAD+	all-trans-retinal + NADH		Mesocricetus auratus	-	-	285602, 285650	-	-	?
all-trans-retinol + NAD+	all-trans-retinal + NADH		Equus caballus	-	-	285648	-	285648	?
all-trans-retinol + NAD+	all-trans-retinal + NADH		Homo sapiens	-	ADH4 might be involved in biosynthesis of retinoic acid	656058	-	-	r
allyl alcohol + NAD+	prop-2-en-1-al + NADH		Vicia faba	-	-	285559	-	-	?
allyl alcohol + NAD+	prop-2-en-1-al + NADH		Zea mays	-	-	285630, 285652	-	-	?
allyl alcohol + NAD+	prop-2-en-1-al + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
allyl alcohol + NAD+	prop-2-en-1-al + NADH		Zymomonas mobilis	-	-	285622, 285623	-	-	?
allyl alcohol + NAD+	prop-2-en-1-al + NADH		Euglena longa	-	-	285638	-	-	?
allyl alcohol + NAD+	prop-2-en-1-al + NADH		Saccharomyces cerevisiae	-	no activity	285642	-	-	-
allyl alcohol + NAD+	acrolein + NADH		Mus musculus	-	-	655233	-	-	?
allyl alcohol + NAD+	acrolein + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
allyl alcohol + NAD+	acrolein + NADH		Equus caballus	-	-	655233	-	-	?
allyl alcohol + NAD+	acrolein + NADH		Mus musculus	-	-	655233	product is toxic in mouse hepatocytes due to cell protein carbonylation following exposure to crotyl alcohol	-	?
allylalcohol + NAD+	prop-2-enal + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	?
alpha-tetralone + NADH + H+	(S)-alpha-tetralol + NAD+		Thermus thermophilus	-	more than 99% enantiomeric excess	684583	-	-	?
anisaldehyde + NADH	anisic alcohol + NADH		Sulfolobus solfataricus	-	-	285621, 285625	-	-	?
anisaldehyde + NADH + H+	anisic alcohol + NAD+		Sulfolobus solfataricus	-	-	678363	-	-	?
benzaldehyde + NADH	benzyl alcohol + NAD+		Mus musculus	-	reduced by isoenzyme A2 and C2, no activity with isoenzyme B2	285603	-	-	r
benzaldehyde + NADH + H+	benzyl alcohol + NAD+		Sulfolobus solfataricus	-	-	679883	-	-	?
benzaldehyde + NADH + H+	benzyl alcohol + NAD+		Cucumis melo	-	1.2% of the activity with acetaldehyde	670572	-	-	?
benzaldehyde + NADH + H+	benzyl alcohol + NAD+		Pseudomonas putida	Q76HN6	3% activity compared to benzyl alcohol	678779	-	-	r
benzaldehyde + NADH + H+	benzyl alcohol + NAD+		Thermus thermophilus	-	14% of the activity with 2,2,2-trifluoroacetophenone	684583	-	-	?
benzaldehyde + NADH + H+	benzyl alcohol + NAD+		Devosia riboflavina	-	21% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
benzaldehyde + NADH + H+	benzyl alcohol + NAD+		Dipodascus capitatus	-	74% of the activity with N-benzyl-3-pyrrolidinone	687850	-	-	?
benzoin + NADH + H+	1,2-diphenylethane-1,2-diol		Devosia riboflavina	-	13% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
benzoylformic acid + NADPH + H+	mandelate + NADP+		Candida parapsilosis	B2KJ46	2.4% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
benzyl aclohol + NAD+	benzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	682630	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH		Mus musculus	Q9QYY9	-	654730	-	-	r
benzyl alcohol + NAD+	benzaldehyde + NADH		Homo sapiens	-	-	285568, 285569, 285571, 285651	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH		Mesocricetus auratus	-	-	285602	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH		Equus caballus	-	-	285597	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH		Sulfolobus solfataricus	-	-	285621, 285625	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH		Fragaria x ananassa	-	-	669027	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH		Coturnix coturnix	-	-	285615	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH		Zea mays	-	no activity	285630	-	-	-
benzyl alcohol + NAD+	benzaldehyde + NADH		Mus musculus	-	oxidized by isoenzyme A2 and C2 no activity with isoenzyme B2	285603	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH		Rattus norvegicus	-	oxidation with isoenzyme ADH-1 and ADH-3, no activity with isoenzyme ADH-2	285604	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Homo sapiens	-	-	686331	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Saccharomyces cerevisiae	-	-	697669	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	r
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Equus caballus	-	-	697669	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	680428	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	678116, 678121	-	-	r
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Methylobacterium extorquens	-	-	669027	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Thermoanaerobacter brockii	-	-	697669	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Sulfolobus sp.	P50381	-	680428	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	r
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Thermus sp.	B2ZRE3	-	695811	178% activity compared to cyclohexanone	-	r
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Pseudomonas putida	Q76HN6	100% activity	678779	-	-	r
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Brevibacterium sp.	-	199% of the activity with 2-phenylethanol	669540	-	-	?
benzyl alcohol + NAD+	benzaldehyde + NADH + H+		Thermus sp.	B2ZRE3	47% activity compared to cyclohexanol	695811	154% activity compared to cyclohexanone	-	r
benzylacetone + NADH + H+	4-phenylbutan-2-ol + NAD+		Dipodascus capitatus	-	activity is 1.3fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
benzylalcohol + NAD+	benzaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	681763	-	-	r
benzylalcohol + NAD+	benzaldehyde + NADH + H+		Sulfolobus solfataricus	Q9UXF1	-	681629	-	-	?
benzylalcohol + NAD+	benzaldehyde + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	weak activity	668532	-	-	r
benzyloxycarbonyl-3-pyrrolidinone + NADH + H+	(S)-benzyloxycarbonyl-3-pyrrolidinol + NAD+		Devosia riboflavina	-	production with 99.6% enantiomeric excess	688442	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Drosophila melanogaster	-	-	285619	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Homo sapiens	-	-	285575, 285608	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Mesocricetus auratus	-	-	285602, 285650	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Equus caballus	-	-	285647	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Sulfolobus solfataricus	-	-	285621	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Oncorhynchus mykiss	-	-	285614	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Sporotrichum pulverulentum	-	-	285639	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Drosophila virilis, Drosophila simulans	-	-	285619	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Euglena longa	-	-	285638	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Zea mays	-	no activity	285652	-	-	-
butan-2-ol + NAD+	butan-2-one + NADH		Zea mays	-	weak activity	285630	-	-	?
butan-2-ol + NAD+	butan-2-one + NADH		Equus caballus	-	(R)-2-butanol and (S)-2-butanol	285586	-	285586	?
butan-2-one + NADH	butan-2-ol + NAD+		Equus caballus	-	-	285586	-	285586	r
butan-2-one + NADH	butan-2-ol + NAD+		Sulfolobus solfataricus	-	-	285621	-	-	r
butanal + NADH	1-butanol + NAD+ + H+		Leifsonia sp.	-	% of the activity with phenyl trifluoromethyl ketone	667255	-	-	ir
butanol + NAD+	butyraldehyde + NADH		Drosophila melanogaster	-	-	285619	-	-	?
butanol + NAD+	butyraldehyde + NADH		Homo sapiens	-	-	285571, 285573, 285575, 285608, 285651	-	-	?
butanol + NAD+	butyraldehyde + NADH		Saccharomyces cerevisiae	-	-	285645	-	-	?
butanol + NAD+	butyraldehyde + NADH		Oryctolagus cuniculus	-	-	285600	-	-	?
butanol + NAD+	butyraldehyde + NADH		Zea mays	-	-	285630, 285652	-	-	?
butanol + NAD+	butyraldehyde + NADH		Mesocricetus auratus	-	-	285602, 285650	-	-	?
butanol + NAD+	butyraldehyde + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
butanol + NAD+	butyraldehyde + NADH		Equus caballus	-	-	285597	-	-	?
butanol + NAD+	butyraldehyde + NADH		Sulfolobus solfataricus	-	-	285621	-	-	?
butanol + NAD+	butyraldehyde + NADH		Oncorhynchus mykiss	-	-	285614	-	-	?
butanol + NAD+	butyraldehyde + NADH		Triticum monococcum	-	-	285633	-	-	?
butanol + NAD+	butyraldehyde + NADH		Coturnix coturnix	-	-	285615	-	-	?
butanol + NAD+	butyraldehyde + NADH		Drosophila virilis, Drosophila simulans	-	-	285619	-	-	?
butanol + NAD+	butyraldehyde + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
butanol + NAD+	butyraldehyde + NADH		Triticum turgidum	-	-	285632	-	-	?
butanol + NAD+	butyraldehyde + NADH		Euglena longa	-	-	285638	-	-	?
butanol + NAD+	butyraldehyde + NADH		Alligator mississippiensis	-	-	285656	-	-	?
butanol + NAD+	butyraldehyde + NADH		Saccharomyces cerevisiae	-	weak	285642	-	-	-
butanol + NAD+	butyraldehyde + NADH		Zymomonas mobilis	-	activity with ADH I, no activity with ADH II	285623	-	-	?
butanol + NAD+	butyraldehyde + NADH		Zymomonas mobilis	-	oxidized by enzyme form ADH-I, no activity with enzyme form ADH-II	285622	-	-	-
butanol + NAD+	butyraldehyde + NADH		Rattus norvegicus	-	pH 10.0: oxidized by ADH-1 and ADH-3, no activity with isoenzyme ADH-2	285604	-	-	?
butanol + NAD+	butanal + NADH		Crocus sativus	-	-	654140	-	-	?
butanol + NAD+	n-butanal + NADH		Equus caballus	P00327	-	654743	-	-	?
butanol + NAD+	butyraldehyde + NADH + H+		Thermus sp.	B2ZRE3	-	695811	359% activity compared to cyclohexanone	-	r
butanol + NAD+	butyraldehyde + NADH + H+		Equus caballus	-	immobilized HLAD shows about 95% reaction rate and free HLAD shows about 90% reaction rate with butanol compared to ethanol at pH 8.8 and 30�C	697660	-	-	?
butylaldehyde + NADH	n-butanol + NAD+		Acetobacter pasteurianus	-	best substrate for isozyme ADH II	655058	-	-	r
butyraldehyde + NADH	n-butanol + NAD+		Equus caballus	-	-	285597	-	-	r
butyraldehyde + NADH	n-butanol + NAD+		Desulfovibrio gigas	-	-	285654	-	-	r
butyraldehyde + NADH	n-butanol + NAD+		Zymomonas mobilis	-	activity with enzyme form ADH I, no activity with enzyme form ADH II	285623	-	285623	r
butyraldehyde + NADH + H+	butanol + NAD+		Cucumis melo	-	56% of the activity with acetaldehyde	670572	-	-	?
butyraldehyde + NADH + H+	n-butanol + NAD+		Sulfolobus solfataricus	-	-	679883	-	-	?
butyraldehyde + NADPH + H+	butanol + NADP+		Cucumis melo	-	22% of the activity with NADH	670572	-	-	?
chloroacetone + NADH + H+	1-chloropropan-2-ol + NAD+		Leifsonia sp.	-	238% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
chloroacetone + NADH + H+	1-chloropropan-2-ol + NAD+		Devosia riboflavina	-	41.7fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
choline + NAD+	? + NADH + H+		Pseudomonas putida	Q76HN6	3% activity compared to benzyl alcohol	678779	-	-	?
cinnamyl alcohol + NAD+	cinnamaldehyde + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
cinnamyl alcohol + NAD+	cinnamaldehyde + NADH		Equus caballus	-	-	285647	-	-	?
cinnamyl alcohol + NAD+	cinnamaldehyde + NADH		Euglena longa	-	-	285638	-	-	?
cis-4-methylcyclohexanol + NAD+	4-methylcyclohexanone + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
crotyl alcohol + NAD+	crotonaldehyde + NADH		Mus musculus, Equus caballus	-	-	655233	-	-	?
crotyl alcohol + NAD+	crotonaldehyde + NADH		Thermomicrobium roseum	-	-	655262	-	-	?
crotyl alcohol + NAD+	crotonaldehyde + NADH		Mus musculus	-	-	655233	product is toxic in mouse hepatocytes due to cell protein carbonylation following exposure to crotyl alcohol	-	?
crotyl alcohol + NAD+	crotonaldehyde + NADH		Equus caballus	-	product is toxic in mouse hepatocytes due to cell protein carbonylation following exposure to crotyl alcohol	655233	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Homo sapiens	-	-	285568, 285569	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Rattus norvegicus	-	-	285604	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Mesocricetus auratus	-	-	285602, 285650	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Triticum monococcum	-	-	285633	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Coturnix coturnix	-	-	285615	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Triticum turgidum	-	-	285632	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Alligator mississippiensis	-	-	285656	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Zea mays	-	no activity	285630	-	-	-
cyclohexanol + NAD+	cyclohexanone + NADH		Mus musculus	-	oxidized by isoenzyme A2, no activity with isoenzymes B2 and C2	285603	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH		Macaca mulatta	-	reaction is catalyzed by the cathodic pyrazole-sensitive enzyme, no activity with the cathodic pyrazole-insensitive enzyme and by the anodic pyrazole-insensitive enzyme	285580	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH + H+		Sulfolobus solfataricus	-	-	678116, 678121, 681763	-	-	?
cyclohexanol + NAD+	cyclohexanone + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
cyclohexanol + NAD+	cyclohexanone + NADH + H+		Thermus sp.	B2ZRE3	100% activity	695811	100% activity	-	r
cyclohexanol + NAD+	cyclohexanone + NADH + H+		Thermus thermophilus	-	13% of the activity with (S)-(-)-1-phenylethanol	684583	-	-	?
cyclohexanone + NADH	cyclohexanol + NAD+		Equus caballus	-	-	285583, 285597	-	-	?
cyclohexanone + NADH	cyclohexanol + NAD+		Pseudomonas fluorescens	-	best cyclic ketone substrate	654294	-	-	?
cyclohexanone + NADH	cyclohexanal + NAD+		Homo sapiens	-	-	655206	-	-	?
cyclohexanone + NADH + H+	?		Dipodascus capitatus	-	activity is 2.1fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
cyclopentanol + NAD+	? + NADH		Triticum monococcum	-	-	285633	-	-	?
cyclopentanol + NAD+	? + NADH		Triticum turgidum	-	-	285632	-	-	?
cyclopentanone + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	1% activity compared to cyclohexanone	695811	-	-	?
cyclopetanone + NADH	cyclopentanol + NADH		Sulfolobus solfataricus	-	-	285621	-	-	?
D-glucitol + NAD+	? + NADH		Triticum monococcum	-	-	285633	-	-	?
D-glucitol + NAD+	? + NADH		Triticum turgidum	-	-	285632	-	-	?
decahydro-2-naphthol + NAD+	?		Thermus sp.	B2ZRE3	37% activity compared to cyclohexanol	695811	-	-	?
decyl aldehyde + NADH + H+	1-decanol + NAD+		Pseudomonas putida	Q76HN6	21% activity compared to benzyl alcohol	678779	-	-	?
diacetyl + NADH + H+	?		Devosia riboflavina	-	16.1fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
digitose + NAD+	? + NADH		Homo sapiens	-	-	285571	-	-	?
dihydro-4,4-dimethyl-2,3-furandione + NADH + H+	?		Devosia riboflavina	-	13.1fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
docosanol + NAD+	? + NADH + H+		Equus caballus	-	immobilized HLAD shows about 60% reaction rate and free HLAD shows about 20% reaction rate with docosanol compared to ethanol at pH 8.8 and 30�C	697660	-	-	?
dodecanol + NAD+	dodecanal + NADH + H+		Equus caballus	-	immobilized HLAD shows about 60% reaction rate and free HLAD shows about 35% reaction rate with dodecanol compared to ethanol at pH 8.8 and 30�C	697660	-	-	?
ethanol + 2 NAD+ + H2O	acetic acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	best substrate	712962	-	-	r
ethanol + 2 NAD+ + H2O	acetic acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 45% of the activity with 1-octanol	712962	-	-	r
ethanol + 2 NADP+ + H2O	acetic acid + 2 NADPH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962	-	-	r
ethanol + 3-benzoylpyridine-adenine dinucleotide	acetaldehyde + ?		Equus caballus	-	rapid equilibrium bi bi mechanism	285588	-	-	-
ethanol + beta-NAD+	acetaldehyde + NADH + H+		Saccharomyces cerevisiae	-	-	689887	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Drosophila melanogaster	-	-	285619, 285620	-	-	-
ethanol + NAD+	acetaldehyde + NADH		Drosophila melanogaster	-	-	285598	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Mus musculus	-	-	655479, 667832	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Escherichia coli	-	-	660650	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	-	285565, 285567, 285568, 285569, 285572, 285573, 285575, 285608, 285651, 655197, 655206, 655479	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Rattus norvegicus	-	-	285565	-	-	-
ethanol + NAD+	acetaldehyde + NADH		Rattus norvegicus	-	-	285606	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Saccharomyces cerevisiae	-	-	285642	-	-	-
ethanol + NAD+	acetaldehyde + NADH		Saccharomyces cerevisiae	-	-	655735, 655741	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Saccharomyces cerevisiae	P00331	-	684586	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Saccharomyces cerevisiae	-	-	285645	-	285645	r
ethanol + NAD+	acetaldehyde + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Oryctolagus cuniculus	-	-	285600	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Geobacillus stearothermophilus	-	-	656475	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Emericella nidulans	-	-	285636	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Zea mays	-	-	285630, 285631, 285652	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Glycine max	-	-	285626	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Petroselinum crispum	-	-	285627	-	285627	?
ethanol + NAD+	acetaldehyde + NADH		Entamoeba histolytica	-	-	656604	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Pseudomonas aeruginosa	-	-	660650	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Brassica napus	-	-	285629	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Natronomonas pharaonis	-	-	686626	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Camellia sinensis	-	-	285628	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Klebsiella pneumoniae	-	-	660650	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Mesocricetus auratus	-	-	285602, 285650	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Equus caballus	-	-	285590, 285647, 285657	-	-	-
ethanol + NAD+	acetaldehyde + NADH		Equus caballus	-	-	655206, 655233	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Equus caballus	-	-	285583	-	285583	r
ethanol + NAD+	acetaldehyde + NADH		Equus caballus	-	-	285596	-	285596	r
ethanol + NAD+	acetaldehyde + NADH		Equus caballus	-	-	285597	-	285597	r
ethanol + NAD+	acetaldehyde + NADH		Zymomonas mobilis	-	-	285622	-	-	-
ethanol + NAD+	acetaldehyde + NADH		Zymomonas mobilis	-	-	285623	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Macaca mulatta	-	-	285580	-	285580	r
ethanol + NAD+	acetaldehyde + NADH		Oryza sativa	-	-	285561	-	285561	r
ethanol + NAD+	acetaldehyde + NADH		Hafnia alvei	-	-	660650	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Oncorhynchus mykiss	-	-	285614	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Fragaria x ananassa	-	-	669027	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Klebsiella oxytoca	-	-	660650	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Triticum monococcum	-	-	285633	-	-	-
ethanol + NAD+	acetaldehyde + NADH		Chlamydomonas moewusii	-	-	285624	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Coturnix coturnix	-	-	285615	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Sporotrichum pulverulentum	-	-	285639	-	285639	r
ethanol + NAD+	acetaldehyde + NADH		Thermoanaerobacter brockii	-	-	655735	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Drosophila virilis	-	-	285619	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Ctenopharyngodon idella	-	-	285557	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Drosophila simulans	-	-	285619	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Saimiri sciureus	-	-	285579	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Saara hardwickii	-	-	285607	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Triticum turgidum	-	-	285632	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Euglena longa	-	-	285638	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Alligator mississippiensis	-	-	285656	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Neurospora crassa	Q9P6C8	-	684614	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Acetobacter pasteurianus	-	-	655058	acetaldehyde is the best substrate for isozyme ADH I	-	r
ethanol + NAD+	acetaldehyde + NADH		Thermomicrobium roseum	-	best substrate	655262	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	class III isoenzyme chi-ADH oxidizes ethanol very poorly	285571	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	no oxidation with class III enzyme	285566	-	-	-
ethanol + NAD+	acetaldehyde + NADH		Rattus norvegicus	-	isoenzyme ADH-1 and ADH-3, no activity with isoenzyme ADH-2	285604	-	285604	-
ethanol + NAD+	acetaldehyde + NADH		Desulfovibrio gigas	-	the reduction of acetaldehyde is 4.9fold faster than the oxidation of ethanol	285654	-	285654	r
ethanol + NAD+	acetaldehyde + NADH		Candida sp.	-	the reduction of acetaldehyde of ADH-MII is about 7times higher than that of the oxidation of ethanol	285637	-	285637	r
ethanol + NAD+	acetaldehyde + NADH		Mus musculus	-	no activity with isoenzyme B2, oxidized by isoenzyme A2 and C2, role of the major liver isoenzyme A2 in ethanol metabolism	285603	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Equus caballus	-	plays an important role in the metabolism of ethanol	285657	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	chi-ADH plays an important role in the metabolism of long chain alcohols and aldehydes	285576	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	the anodic enzyme form may contribute significantly to alcohol elimination in man, particularly at high concentrations when the other enzyme species are saturated	285573	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	the enzyme plays a significant role in first-pass metabolism of ethanol in human	285651	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	enzyme is responsible for the major ethanol oxidation capacity in the body. The products acetaldehyde and NADH are responsible for the most of the toxic effects and metabolic disturbances produced by ethanol ingestion	285565	-	285565	?
ethanol + NAD+	acetaldehyde + NADH		Saccharomyces cerevisiae	-	rate-limiting step of the alcoholic fermentation	655741	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Equus caballus	P00327	isomerization of the enzyme-NAD+ complex is the rate-limiting step for acetaldehyde reduction by the wild-type enzyme	654743	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Crocus sativus	-	no cooperativity between the 2 active sites of the enzyme	654140	-	-	r
ethanol + NAD+	acetaldehyde + NADH		Mus musculus	-	DH3 plays an important role in systemic ethanol metabolism at higher levels of blood ethanol through activation by cytoplasmic solution hydrophobicity	667832	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Brevibacterium sp.	-	76% of the activity with 2-phenylethanol	669540	-	-	?
ethanol + NAD+	acetaldehyde + NADH		Geobacillus stearothermophilus	P42328	proton and hydride equivalent transfer in the alcohol dehydrogenase enzymatic reaction are modulated by the correlated motions between NAD+ and the cofactor domain	685180	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Mus musculus	-	-	699982	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Homo sapiens	-	-	691867	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Saccharomyces cerevisiae	-	-	667307, 669148, 695705, 697658, 697669, 699019	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Saccharomyces cerevisiae	-	-	668532	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Euglena gracilis	B8QU18	-	699249	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Equus caballus	-	-	668487, 697669	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Zymomonas mobilis	-	-	667340	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	285621	-	-	-
ethanol + NAD+	acetaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	678116, 680428, 681372, 681763	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Methylobacterium extorquens	-	-	669027	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Thermoanaerobacter brockii	-	-	697669	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Mucor circinelloides	-	-	667237	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Anastrepha fraterculus	-	-	698114	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Flavobacterium frigidimaris	Q8L3C9	-	668532	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Sulfolobus solfataricus	Q9UXF1	-	681629	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Sulfolobus sp.	P50381	-	680428	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Picrophilus torridus	Q6L0S1	-	684620	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Schizosaccharomyces pombe	Q09669	-	684960	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Thermoanaerobacter ethanolicus	Q0PH30	-	695536	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Anastrepha obliqua	-	-	698114	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Geobacillus thermoglucosidasius	Q6RS93	-	699071	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Thermoplasma acidophilum	Q9HIM3	100% activity	700124	-	-	?
ethanol + NAD+	acetaldehyde + NADH + H+		Corynebacterium glutamicum R	-	no activity with NADP+, in reverse reaction no activity with NADPH	684612	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Natronomonas pharaonis	-	the enzyme is highly specific for ethanol with NAD+ as the coenzyme	686626	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Thermus sp.	B2ZRE3	88% activity compared to cyclohexanol	695811	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Homo sapiens	P00326, P08319	substrate for isozyme ADH1C, extremely poor substrate for isozyme ADH3	701322	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Homo sapiens	P00326, P08319	substrate for isozyme ADH2	701322	-	-	r
ethanol + NAD+	acetaldehyde + NADH + H+		Homo sapiens	P00326, P08319	substrate for isozyme ADH4	701322	-	-	r
ethanol + NAD+	aldehyde + NADH + H+		Equus caballus	-	immobilized HLAD shows 100% reaction rate and free HLAD shows about 55% reaction rate with ethanol at pH 8.8 and 30�C	697660	-	-	?
ethanol + NADP+	acetaldehyde + NADPH + H+		Picrophilus torridus	Q6L0S1	8.5% of the activity with ethanol and NAD+	684620	-	-	?
ethyl 3-methyl-2-oxobutyrate + NADH + H+	ethyl-2-hydroxy-3-methylbutyrate + NAD+		Leifsonia sp.	-	33% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
ethyl 3-oxobutanoate + NADH + H+	ethyl 3-hydroxybutanoate + NAD+		Leifsonia sp.	-	309% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
ethyl 3-oxobutyrate + NADH + H+	ethyl (S)-3-hydroxybutyrate + NAD+		Saccharomyces cerevisiae	-	-	695705	-	-	-
ethyl 4-bromo-3-oxobutanoate + NADH + H+	ethyl 4-bromo-3-hydroxybutanoate		Leifsonia sp.	-	511% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
ethyl 4-chloro-3-oxobutanoate + NADH + H+	ethyl 4-chloro-3-hydroxybutanoate + NAD+		Leifsonia sp.	-	809% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
ethyl 4-chloroacetoacetate + NADH + H+	?		Devosia riboflavina	-	6.8fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
ethyl 4-chloroacetoacetate + NADPH	?		Candida parapsilosis	B2KJ46	activity is 1.48fold higher than with 2-hydroxyacetophenone and NADPH	684556	-	-	?
ethyl acetoacetate + NADH + H+	?		Devosia riboflavina	-	42.4fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
ethyl benzoylformate + NADH + H+	ethyl (R)-(-)-mandelate + NAD+		Thermus thermophilus	-	95% enantiomeric excess	684583	-	-	?
ethyl pyruvate + NADH + H+	ethyl 2-hydroxypropanoate + NAD+		Leifsonia sp.	-	488% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
ethyl trifluoroacetoacetate + NADPH + H+	1-ethoxy-2,2,2-trifluoroethanol + NADP+		Candida parapsilosis	B2KJ46	4.3% of the activity with 2-hydroxyacetophenone and NADPH	684556	-	-	?
ethylene glycol + NAD+	? + NADH		Homo sapiens	-	-	285568, 285569	-	-	?
ethylene glycol + NAD+	? + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
ethylene glycol + NAD+	? + NADH		Coturnix coturnix	-	no activity	285615	-	-	-
ethylene glycol + NAD+	? + NADH		Homo sapiens	-	class III isoenzyme chi-ADH shows no activity	285571	-	-	-
ethylene glycol + NAD+	? + NADH		Mus musculus	-	oxidized by isoenzyme A2, no activity with isoenzyme B2 and C2	285603	-	-	?
ethylene glycol + NAD+	?		Pseudomonas aeruginosa	-	poor substrate	657302	-	-	r
ethylenglycol + NAD+	? + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
formaldehyde + NAD+	methanol + NADH		Desulfovibrio gigas	-	-	285654	-	-	?
formaldehyde + NAD+	methanol + NADH		Zymomonas mobilis	-	activity with ADH I, no activity with ADH II	285623	-	-	?
formaldehyde + NAD+	methanol + NADH		Mus musculus	-	reduced by isoenzyme A2, no activity with isoenzyme B2 and C2	285603	-	-	r
formaldehyde + NADH + H+	methanol + NAD+		Saccharomyces cerevisiae	-	-	688435	-	-	?
furfural + NADH	furfuryl alcohol + NADH		Zymomonas mobilis	-	activity with enzyme form ADH I, no activity with enzyme form ADH II	285623	-	285623	r
furfural + NADH + H+	furfuryl alcohol + NADH		Saccharomyces cerevisiae	P00330	mutant enzyme S109P/L116S/Y294C	690211	-	-	?
furfuryl alcohol + NAD+	furfural + NADH		Homo sapiens	-	-	285571	-	-	?
furfuryl alcohol + NAD+	furfural + NADH		Zymomonas mobilis	-	activity with ADH I, no activity with ADH II	285623	-	285623	r
glutaraldehyde + NADH + H+	?		Devosia riboflavina	-	70.8fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
glycerol + 2 NAD+ + H2O	? + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 45% of the activity with ethanol	712962	-	-	r
glycerol + NAD+	dihydroxyacetone + NADH		Fragaria x ananassa	-	-	669027	-	-	?
glycerol + NAD+	dihydroxyacetone + NADH		Crocus sativus	-	-	654140	-	-	?
glycerol + NAD+	dihydroxyacetone + NADH + H+		Methylobacterium extorquens	-	-	669027	-	-	?
heptaldehyde + NADH + H+	? + NAD+		Pseudomonas putida	Q76HN6	33% activity compared to benzyl alcohol	678779	-	-	?
heptan-2-ol + NAD+	heptan-2-one + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
heptan-4-ol + NAD+	heptan-4-one + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
hexadecanol + NAD+	hexadecanal + NADH		Oncorhynchus mykiss	-	very low activity	285614	-	-	?
hexadecanol + NAD+	hexadecanal + NADH + H+		Equus caballus	-	immobilized HLAD shows about 60% reaction rate and free HLAD shows about 15% reaction rate with hexadecanol compared to ethanol at pH 8.8 and 30�C	697660	-	-	?
hexaldehyde + NADH + H+	1-heptanol + NAD+		Pseudomonas putida	Q76HN6	7% activity compared to benzyl alcohol	678779	-	-	?
hexan-1-ol + NAD+	n-hexanal + NADH		Zea mays	-	-	285630, 285652	-	-	?
hexan-1-ol + NAD+	n-hexanal + NADH		Mesocricetus auratus	-	-	285602	-	-	?
hexan-1-ol + NAD+	n-hexanal + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
hexan-1-ol + NAD+	n-hexanal + NADH		Triticum monococcum	-	-	285633	-	-	?
hexan-1-ol + NAD+	n-hexanal + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
hexan-1-ol + NAD+	n-hexanal + NADH		Triticum turgidum	-	-	285632	-	-	?
hexan-2-ol + NAD+	2-hexanone + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
hexanal + NADH + H+	1-hexanone + NAD+		Cucumis melo	-	49% of the activity with acetaldehyde	670572	-	-	?
hexanal + NADH + H+	n-hexanol + NAD+		Devosia riboflavina	-	22.3fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
hexanal + NADPH + H+	1-hexanone + NADP+		Cucumis melo	-	24% of the activity with NADH	670572	-	-	?
hexanol + NAD+	n-hexanal + NADH		Mus musculus	-	-	285603	-	-	?
hexanol + NAD+	n-hexanal + NADH		Homo sapiens	-	-	285575	-	-	-
hexanol + NAD+	n-hexanal + NADH		Homo sapiens	-	-	285576, 285608	-	-	?
hexanol + NAD+	n-hexanal + NADH		Mesocricetus auratus	-	-	285650	-	-	-
hexanol + NAD+	n-hexanal + NADH		Equus caballus	-	-	285597	-	285597	?
hexanol + NAD+	n-hexanal + NADH		Equus caballus	-	-	285647	-	-	?
hexanol + NAD+	n-hexanal + NADH		Sporotrichum pulverulentum	-	-	285639	-	-	?
hexanol + NAD+	n-hexanal + NADH		Alligator mississippiensis	-	-	285656	-	-	?
hexanol + NAD+	n-hexanal + NADH		Zymomonas mobilis	-	activity with ADH I, no activity with ADH II	285623	-	-	-
hexanol + NAD+	hexaldehyde + NADH		Mus musculus	-	-	655479	-	-	?
hexanol + NAD+	hexanal + NADH		Homo sapiens	-	-	655479	-	-	?
hydoxyacetone + NADH + H+	propane-1,2-diol + NAD+		Dipodascus capitatus	-	27% of the activity with N-benzyl-3-pyrrolidinone	687850	-	-	?
hydrocinnamaldehyde + NADH + H+	hydrocinnamyl alcohol + NAD+		Pseudomonas putida	Q76HN6	12% activity compared to benzyl alcohol	678779	-	-	r
hydrocinnamyl alcohol + NAD+	hydrocinnamaldehyde + NADH + H+		Pseudomonas putida	Q76HN6	31% activity compared to benzyl alcohol	678779	-	-	r
iso-propanol + NAD+	isopropanal + NADH + H+		Sulfolobus solfataricus	Q9UXF1	-	681629	-	-	?
isoamylalcohol + 2 NAD+ + H2O	? + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 5% of the activity with 1-octanol	712962	-	-	r
isobutyl alcohol + NAD+	? + NADH		Homo sapiens	-	-	285575	-	-	?
isobutyraldehyde + NADH + H+	isobutanol + NAD+		Sulfolobus solfataricus	-	-	697839	-	-	r
isobutyramide + NAD+	?		Homo sapiens	-	-	656058	-	-	r
isopentanol + NAD+	? + NADH + H+		Euglena gracilis	B8QU18	low affinity	699249	-	-	?
isopentenyl alcohol + NAD+	isopentanone + NADH		Homo sapiens	-	-	285575	-	-	?
isopropanol + 2 NAD+ + H2O	? + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 10% of the activity with 1-octanol	712962	-	-	r
isopropanol + 2 NAD+ + H2O	? + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 15% of the activity with 1-octanol	712962	-	-	r
isopropanol + NAD+	acetone + NADH + H+		Saccharomyces cerevisiae	-	-	667307	-	-	?
isopropanol + NAD+	acetone + NADH + H+		Euglena gracilis	B8QU18	low affinity	699249	-	-	?
isopropanol + NAD+	2-propanone + NADH + H+		Thermus sp.	B2ZRE3	-	695811	-	-	r
levulinic acid + NADH + H+	?		Devosia riboflavina	-	11% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
m-chlorophenacyl chloride + NADH + H+	2-chloro-1-(3-chlorophenyl)ethanol + NAD+		Devosia riboflavina	-	4.6fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
m-nitrobenzaldehyde + NAD+	m-nitrobenzyl alcohol + NADH		Rattus norvegicus	-	-	285604	-	285604	-
m-nitrobenzaldehyde + NAD+	m-nitrobenzyl alcohol + NADH + H+		Homo sapiens	-	substrate of class IV ADH	686331	-	-	?
m-nitrobenzaldehyde + NADH + H+	m-nitrobenzyl alcohol + NAD+		Homo sapiens	-	substrate of class IV ADH isozyme	697802	-	-	r
methanol + 2 NAD+ + H2o	formic acid + 2 NADH + 2 H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 25% of the activity with 1-octanol	712962	-	-	r
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	-	285567	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Oncorhynchus mykiss	-	-	285614	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Methylobacterium extorquens	-	-	669027	-	-	r
methanol + NAD+	formaldehyde + NADH + H+		Fragaria x ananassa	-	-	669027	-	-	ir
methanol + NAD+	formaldehyde + NADH + H+		Alligator mississippiensis	-	-	285656	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Picrophilus torridus	Q6L0S1	-	684620	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Corynebacterium glutamicum R	-	-	684612	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	no activity	285576	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Zea mays	-	no activity	285630	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Meyerozyma guilliermondii	-	no activity	285640	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Zymomonas mobilis	-	no activity	285622, 285623	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Coturnix coturnix	-	no activity	285615	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Sporotrichum pulverulentum	-	no activity	285639	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Thermomicrobium roseum	-	low activity	655262	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Candida sp.	-	reaction is extremly weak	285637	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	anodic enzyme form shows no activity	285573	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Oryctolagus cuniculus	-	no activity at pH 7.5, slight activity at pH 10.8	285600	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Mus musculus	-	weak activity with isoenzyme A2, no activity with isoenzyme B2 and C2	285603	-	-	?, r
methanol + NAD+	formaldehyde + NADH + H+		Rattus norvegicus	-	oxidized with ADH-3, no activity with ADH-1 and ADH-2	285604	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	class I isoenzymes	285568	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	no activity with isoenzyme beta3,beta3	285575	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Saimiri sciureus	-	reaction is catalyzed by the pyrazole-sensitive enzyme, no activity with the pyrazole-insensitive enzyme	285579	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Macaca mulatta	-	reaction is catalyzed by the cathodic pyrazole-sensitive enzyme, no activity by the cathodic pyrazole-insensitive enzyme and by the anodic pyrazole-insensitive enzyme	285580	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	activity detected with class II isoenzyme pi-ADH	285569	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	oxidized by isoenzyme beta1,beta1	285575	-	-	?
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	class III isoenzyme chi-ADH shows no activity	285571	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Homo sapiens	-	no activity with class III enzyme	285566	-	-	-
methanol + NAD+	formaldehyde + NADH + H+		Thermoplasma acidophilum	Q9HIM3	49.9% activity compared to ethanol	700124	-	-	?
methyl 3-oxobutanoate + NADH + H+	methyl 3-hydroxybutanoate + NAD+		Leifsonia sp.	-	130% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
methyl 4-bromo-3-oxobutanoate + NADH + H+	methyl 4-bromo-3-hydroxybutanoate + NAD+		Leifsonia sp.	-	164% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
methyl benzoylformate + NADH + H+	methyl (R)-(-)-mandelate + NAD+		Thermus thermophilus	-	92% enantiomeric excess	684583	-	-	?
methyl glyoxal + NADH + H+	?		Devosia riboflavina	-	3.5fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
methyl pyruvate + NADH + H+	methyl 2-hydroxypropanoate + NAD+		Devosia riboflavina	-	18.9fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
methylbenzoylformate + NADH + H+	?		Thermus thermophilus	-	13% of the activity with 2,2,2-trifluoroacetophenone	684583	-	-	?
methylcrotonyl alcohol + NAD+	methylcrotonaldehyde + NADH		Mesocricetus auratus	-	-	285650	-	-	?
N-benzyl-3-piperidone + NADH + H+	N-benzylpiperidin-3-ol + NAD+		Devosia riboflavina	-	2.3fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
N-benzyl-3-pyrrolidinol + NAD+	1-benzylpyrrolidin-3-one + NADH + H+		Dipodascus capitatus	-	33% of the activity with (S)-N-benzyl-3-pyrrolidinol	687850	-	-	?
N-benzyl-3-pyrrolidinone + NADH + H+	(R)-N-benzyl-3-pyrrolidinol + NAD+		Devosia riboflavina	-	(R)-stereoselectivity of the reduction carried out with the heat-treated cells	688442	-	-	r
N-benzyl-3-pyrrolidinone + NADH + H+	(S)-N-benzyl-3-pyrrolidinol + NAD+		Devosia riboflavina	-	-	688442	-	-	r
N-benzyl-3-pyrrolidinone + NADH + H+	(S)-N-benzyl-3-pyrrolidinol + NAD+		Dipodascus capitatus	-	(S)-N-benzyl-3-pyrrolidinol is produced at an enantiomeric excess of more than 99.9%	687850	-	-	r
N-benzyl-4-piperidone + NADH + H+	N-benzylpiperidin-4-ol + NAD+		Devosia riboflavina	-	10.7fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
n-butanal + NADH + H+	n-butanol + NAD+		Corynebacterium glutamicum R	-	-	684612	-	-	?
n-butanol + NAD+	n-butanal + NADH		Homo sapiens	-	-	687976	-	-	?
n-butanol + NAD+	n-butanal + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
n-butanol + NAD+	butanal + NADH		Thermomicrobium roseum	-	low activity	655262	-	-	?
n-butanol + NAD+	butyraldehyde + NADH		Saccharomyces cerevisiae	-	-	655741	-	-	?
n-butanol + NAD+	butylaldehyde + NADH + H+		Homo sapiens	-	-	686331	-	-	?
n-butanol + NAD+	butylaldehyde + NADH + H+		Homo sapiens	-	-	697802	-	-	r
n-butanol + NAD+	butyraldehyde + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
n-butanol + NAD+	n-butanal + NADH + H+		Corynebacterium glutamicum R	-	-	684612	-	-	?
n-butylaldehyde + NADH + H+	butanal + NAD+		Dipodascus capitatus	-	activity is 1.8fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
n-butyraldehyde + NADH + H+	n-butanol + NAD+		Devosia riboflavina	-	7.3fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
n-decanol + NAD+	n-decanal + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
n-hexanol + NAD+	n-hexanal + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
n-hexylaldehyde + NADH + H+	hexanal + NAD+		Dipodascus capitatus	-	activity is 1.6fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
n-octylaldehyde + NADH + H+	octanal + NAD+		Dipodascus capitatus	-	activity is 1.7fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
n-pentanol + NAD+	pentanal + NADH + H+		Corynebacterium glutamicum R	-	-	684612	-	-	?
n-pentylaldehyde + NAD+	n-pentanol + NADH		Zymomonas mobilis	-	-	285623	-	-	r
n-propanol + NAD+	n-propanal + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
n-propanol + NAD+	propanal + NADH		Saccharomyces cerevisiae	-	-	655741	-	-	?
n-propanol + NAD+	propanal + NADH		Equus caballus	P00327	-	654743	-	-	?
n-propanol + NAD+	propionaldehyde + NADH		Thermomicrobium roseum	-	-	655262	-	-	?
n-propanol + NAD+	propanal + NADH + H+		Sulfolobus solfataricus	Q9UXF1	-	681629	-	-	?
n-propanol + NAD+	propanal + NADH + H+		Corynebacterium glutamicum R	-	-	684612	-	-	r
N-tert-butoxycarbonyl-3-pyrrolidinone + NADH + H+	(S)-N-tert-butoxycarbonyl-3-pyrrolidinol + NAD+		Devosia riboflavina	-	production of (S)-N-tert-butoxycarbonyl-3-pyrrolidinol with 99.6% enantiomeric excess	688442	-	-	?
n-valeraldehyde + NADH + H+	n-pentanol + NAD+		Dipodascus capitatus	-	activity is 2.8fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
nonyl aldehyde + NADH + H+	1-nonanol + NAD+		Pseudomonas putida	Q76HN6	25% activity compared to benzyl alcohol	678779	-	-	?
nonylphenol polyethoxylate 9 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	7% activity compared to benzyl alcohol	678779	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Mus musculus	-	-	285603	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Homo sapiens	-	-	285566, 285568, 285569, 285576	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Rattus norvegicus	-	-	285604	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Zea mays	-	-	285630	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Macaca mulatta	-	-	285580	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Coturnix coturnix	-	-	285615	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Alligator mississippiensis	-	-	285656	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Sporotrichum pulverulentum	-	weak activity	285639	-	-	?
octan-1-ol + NAD+	n-octanal + NADH		Zymomonas mobilis	-	activity with ADH I, no activity with ADH II	285623	-	-	?
octan-2-ol + NAD+	octan-2-one + NADH		Homo sapiens	-	-	285571	-	-	?
octan-2-ol + NAD+	octan-2-one + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
octan-2-ol + NAD+	octan-2-one + NADH		Sporotrichum pulverulentum	-	weak activity	285639	-	-	?
octan-2-ol + NAD+	octan-2-one + NADH		Equus caballus	-	(R)-2-octanol and (S)-2-octanol	285586	-	-	?
octanal + NAD+ + H2O	octanoic acid + NADH + H+		Geobacillus thermodenitrificans	A4IP64, A4ISB9	about 25% of the activity with 1-octanol	712962	-	-	r
octanal + NADH	octanol + NAD+		Homo sapiens	-	-	285571	-	-	?
octanal + NADH	octanol + NAD+		Rattus norvegicus	-	-	285604	-	-	?
octanal + NADH	octanol + NAD+		Coturnix coturnix	-	-	285615	-	-	?
octanoic acid + 2 NADH + 2 H+	1-octanol + 2 NAD+ + H2o		Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962	-	-	r
octanol + NAD+	octanal + NADH		Mus musculus	Q9QYY9	-	654730	-	-	?
octanol + NAD+	octanal + NADH		Mus musculus	-	-	697214	-	-	?
octanol + NAD+	octanal + NADH		Homo sapiens	-	-	655197	-	-	?
octanol + NAD+	heptaldehyde + NADH + H+		Thermus sp.	B2ZRE3	-	695811	178% activity compared to cyclohexanone	-	r
octanol + NAD+	octanal + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
octanol + NAD+	octanal + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
octanol + NAD+	octanal + NADH + H+		Equus caballus	-	immobilized and free HLAD show 100% reaction rate with octanol compared to ethanol at pH 8.8 and 30�C	697660	-	-	?
octyl aldehyde + NADH + H+	1-octanol + NAD+		Pseudomonas putida	Q76HN6	29% activity compared to benzyl alcohol	678779	-	-	?
octylphenol polyethoxylate 2 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	59% activity compared to benzyl alcohol	678779	-	-	?
octylphenol polyethoxylate 8 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	7% activity compared to benzyl alcohol	678779	-	-	?
oxalacetic acid + NADH + H+	?		Devosia riboflavina	-	14% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
p-chlorobenzaldehyde + NADH + H+	p-chlorobenzyl alcohol + NAD+		Devosia riboflavina	-	1.2fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
p-methoxybenzyl alcohol + NAD+	p-methoxybenzaldehyde + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	r
p-methoxybenzyl alcohol + NAD+	p-methoxybenzaldehyde + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	r
p-nitrobenzaldehyde + NADH	p-nitrobenzyl alcohol + NAD+		Mus musculus	-	-	285603	-	-	?
p-nitrobenzaldehyde + NADH + H+	p-nitrobenzyl alcohol + NAD+		Homo sapiens	-	substrate of isozyme ADH4	691867	-	-	r
p-nitrobenzyloxycarbonyl-3-pyrrolidinone + NADH + H+	(S)-N-p-nitrobenzyloxycarbonyl-3-pyrrolidinol + NAD+		Devosia riboflavina	-	production with 90.7% enantiomeric excess	688442	-	-	?
p-nitrophenyl octanoate + H2O	p-nitrophenol + octanoate		Equus caballus	-	acid-assisted nucleophilic catalysis involving the ammonium ion of Lys and the thiolate of Cys in the acyl-oxygen cleavage	285594	-	285594	?
pentan-2-ol + NAD+	2-pentanone + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
pentan-2-ol + NAD+	2-pentanone + NADH		Sulfolobus solfataricus	-	-	285621	-	-	?
pentan-2-ol + NAD+	2-pentanone + NADH		Sporotrichum pulverulentum	-	-	285639	-	-	?
pentan-2-ol + NAD+	2-pentanone + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
pentan-2-ol + NAD+	2-pentanone + NADH		Equus caballus	-	(R)-2-pentanol and (S)-2-pentanol	285586	-	285586	r
pentan-3-ol + NAD+	3-pentanone + NADH		Equus caballus	-	-	285586	-	285586	r
pentan-3-ol + NAD+	3-pentanone + NADH		Sulfolobus solfataricus	-	-	285621	-	-	?
pentan-3-ol + NAD+	3-pentanone + NADH + H+		Sulfolobus solfataricus	-	-	697839	-	-	r
pentanal + NADH	1-pentanol + NAD+ + H+		Leifsonia sp.	-	132% of the activity with phenyl trifluoromethyl ketone, in the reverse reaction 5% of the activity with 2-propanol	667255	-	-	?
pentanol + NAD+	pentanone + NADH		Homo sapiens	-	-	285569, 285571, 285573, 285575, 285608, 285651	-	-	?
pentanol + NAD+	pentanone + NADH		Equus caballus	-	-	285647	-	-	?
pentanol + NAD+	pentanone + NADH		Macaca mulatta	-	-	285580	-	-	?
pentanol + NAD+	pentanone + NADH		Sporotrichum pulverulentum	-	-	285639	-	-	?
pentanol + NAD+	pentanone + NADH		Saimiri sciureus	-	-	285579	-	-	?
pentanol + NAD+	pentanone + NADH		Mus musculus	-	oxidized by isoenzyme A2 and B2, no activity with isoenzyme C2	285603	-	-	?
pentanol + NAD+	n-pentanal + NADH		Homo sapiens	-	-	285566	-	-	?
pentanol + NAD+	n-pentanal + NADH		Rattus norvegicus	-	-	285604	-	-	?
pentanol + NAD+	n-pentanal + NADH		Oryctolagus cuniculus	-	-	285600	-	-	?
pentanol + NAD+	n-pentanal + NADH		Zea mays	-	-	285630	-	-	?
pentanol + NAD+	n-pentanal + NADH		Glycine max	-	-	285626	-	-	?
pentanol + NAD+	n-pentanal + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
pentanol + NAD+	n-pentanal + NADH		Triticum monococcum	-	-	285633	-	-	?
pentanol + NAD+	n-pentanal + NADH		Chlamydomonas moewusii	-	-	285624	-	-	?
pentanol + NAD+	n-pentanal + NADH		Coturnix coturnix	-	-	285615	-	-	?
pentanol + NAD+	n-pentanal + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
pentanol + NAD+	n-pentanal + NADH		Triticum turgidum	-	-	285632	-	-	?
pentanol + NAD+	n-pentanal + NADH		Zymomonas mobilis	-	activity with ADH I, no activity with ADH II	285623	-	-	?
pentanol + NAD+	pentanal + NADH + H+		Saccharomyces cerevisiae	-	-	697267	-	-	?
pentanol + NAD+	pentanal + NADH + H+		Saccharomyces carlsbergensis	B6UQD0	-	697267	-	-	?
pentanol + NAD+	valeraldehyde + NADH + H+		Thermus sp.	B2ZRE3	-	695811	240% activity compared to cyclohexanone	-	r
phenyl trifluoromethyl ketone + NADH + H+	(S)-1-phenyltrifluoroethanol + NAD+		Leifsonia sp.	-	-	667255	more than 99% enantiomeric excess	-	?
phenylalaninol + NAD+	? + NADH		Homo sapiens	-	-	285571	-	-	?
phenylethanol + NAD+	phenylacetaldehyde + NADH		Scaptodrosophila lebanonensis	-	R-(+)-phenylethanol and S-(-)-phenylethanol	285616	-	-	?
phenylethanol + NAD+	phenylacetaldehyde + NADH + H+		Devosia riboflavina	-	15% of activity with N-benzyl-3-pyrrolidinol	688442	-	-	?
phenylglyoxylic acid + NADH + H+	hydroxy(phenyl)acetic acid + NAD+		Saccharomyces cerevisiae	-	enzyme covalently immobilized to magnetic Fe3O4 nanoparticles via glutaraldehyde retains 48.77% activity of its original activity	687134	-	-	?
polyoxyethylene 8 decyl ether + NAD+	? + NADH		Pseudomonas putida	Q76HN6	12% activity compared to benzyl alcohol	678779	-	-	?
primary or secondary alcohol + NAD+	aldehyde or ketone + NADH		Pseudomonas aeruginosa	-	-	657302	-	-	r
prop-2-en-1-ol + NAD+	? + NADH		Camellia sinensis	-	140.6% of the activity with ethanol	285628	-	-	?
propan-1,2-diol + NAD+	? + NADH		Desulfovibrio gigas	-	-	285654	-	-	?
propan-1,2-diol + NAD+	? + NADH		Chlamydomonas moewusii	-	-	285624	-	-	?
propan-2-ol + NAD+	acetone + NADH		Drosophila melanogaster	-	-	285598, 285619, 285620	-	-	?
propan-2-ol + NAD+	acetone + NADH		Homo sapiens	-	-	285569	-	-	?
propan-2-ol + NAD+	acetone + NADH		Saccharomyces cerevisiae	-	-	285645	-	-	?
propan-2-ol + NAD+	acetone + NADH		Oryctolagus cuniculus	-	-	285600	-	-	?
propan-2-ol + NAD+	acetone + NADH		Emericella nidulans	-	-	285636	-	-	?
propan-2-ol + NAD+	acetone + NADH		Zea mays	-	-	285652	-	-	?
propan-2-ol + NAD+	acetone + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
propan-2-ol + NAD+	acetone + NADH		Equus caballus	-	-	285647	-	-	?
propan-2-ol + NAD+	acetone + NADH		Zymomonas mobilis	-	-	285623	-	-	-
propan-2-ol + NAD+	acetone + NADH		Sulfolobus solfataricus	-	-	285621	-	-	?
propan-2-ol + NAD+	acetone + NADH		Sporotrichum pulverulentum	-	-	285639	-	-	?
propan-2-ol + NAD+	acetone + NADH		Drosophila virilis, Drosophila simulans	-	-	285619	-	-	?
propan-2-ol + NAD+	acetone + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
propan-2-ol + NAD+	acetone + NADH		Saccharomyces cerevisiae	-	no activity	285642	-	-	-
propan-2-ol + NAD+	acetone + NADH		Zymomonas mobilis	-	very low activity	285622	-	-	-
propan-2-ol + NAD+	acetone + NADH		Desulfovibrio gigas	-	3% of the activity with ethanol	285654	-	-	-
propan-2-ol + NAD+	acetone + NADH + H+		Thermus sp.	B2ZRE3	-	695811	6% activity compared to cyclohexanone	-	r
propanol + NADH	propionaldehyde + NADH		Drosophila melanogaster	-	-	285620	-	-	?
propanol + NADH	propionaldehyde + NADH		Homo sapiens	-	-	285575, 285608, 285651	-	-	?
propanol + NADH	propionaldehyde + NADH		Saccharomyces cerevisiae	-	-	285642, 285645	-	-	?
propanol + NADH	propionaldehyde + NADH		Oryctolagus cuniculus	-	-	285600	-	-	?
propanol + NADH	propionaldehyde + NADH		Zea mays	-	-	285630, 285652	-	-	?
propanol + NADH	propionaldehyde + NADH		Glycine max	-	-	285626	-	-	?
propanol + NADH	propionaldehyde + NADH		Meyerozyma guilliermondii	-	-	285640	-	-	?
propanol + NADH	propionaldehyde + NADH		Zymomonas mobilis	-	-	285622	-	-	-
propanol + NADH	propionaldehyde + NADH		Zymomonas mobilis	-	-	285623	-	285623	-
propanol + NADH	propionaldehyde + NADH		Sulfolobus solfataricus	-	-	285621	-	-	?
propanol + NADH	propionaldehyde + NADH		Oncorhynchus mykiss	-	-	285614	-	-	?
propanol + NADH	propionaldehyde + NADH		Desulfovibrio gigas	-	-	285654	-	-	?
propanol + NADH	propionaldehyde + NADH		Triticum monococcum	-	-	285633	-	-	?
propanol + NADH	propionaldehyde + NADH		Sporotrichum pulverulentum	-	-	285639	-	-	?
propanol + NADH	propionaldehyde + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
propanol + NADH	propionaldehyde + NADH		Triticum turgidum	-	-	285632	-	-	?
propanol + NADH	propionaldehyde + NADH		Euglena longa	-	-	285638	-	-	?
propionaldehyde + NADH	propanol + NAD+		Equus caballus	-	-	285597	-	-	?
propionaldehyde + NADH	propanol + NAD+		Zymomonas mobilis	-	-	285623	-	-	?
propionaldehyde + NADH	propanol + NAD+		Desulfovibrio gigas	-	-	285654	-	-	?
propionaldehyde + NADH	propanol + NAD+		Petroselinum crispum	-	94% of the activity with acetaldehyde	285627	-	-	?
propionaldehyde + NADH + H+	?		Dipodascus capitatus	-	activity is 1.1fold higher than with N-benzyl-3-pyrrolidinone	687850	-	-	?
propiophenone + NADH + H+	1-phenylpropan-1-ol + NAD+		Devosia riboflavina	-	27% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
pyridine-3-aldehyde + NADH + H+	pyridin-3-yl ethanol + NAD+		Devosia riboflavina	-	82% of activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
pyridine-4-aldehyde + NADH + H+	pyridin-4-yl methanol + NAD+		Devosia riboflavina	-	4.4fold higher activity compared to activity with N-benzyl-3-pyrrolidinone	688442	-	-	?
R-(+)-1-phenylethanol + NAD+	1-phenylethanone + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	-
R-(+)-cis-verbenol + NAD+	? + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
R-(+)-trans-bicyclo(2.2.1)-heptanol + NAD+	R-(+)-trans-bicyclo(2.2.1)-heptanal + NADH		Scaptodrosophila lebanonensis	-	R-(+)-trans-bicyclo(2.2.1)-heptanol and S-(-)-trans-bicyclo(2.2.1)-heptanol	285616	-	-	?
rac-3-methylcyclohexanone + NADH + H+	(1S,3S)-3-methylcyclohexanol + NAD+		Thermus sp.	-	-	684246	-	-	?
retinal + NADH + H+	retinol + NAD+		Homo sapiens	-	substrate of isozyme ADH4	691867	-	-	r
retinol + NAD+	retinal + NADH		Homo sapiens	-	-	655197	-	-	?
S-(-)-1-phenylethanol + NAD+	1-phenylethanone + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	-
S-(-)-cis-bicyclo(2.2.1)-heptanol + NAD+	S-(-)-cis-bicyclo(2.2.1)-heptanal + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
secondary alcohol + NAD+	aldehyde + NADH		Geobacillus stearothermophilus	-	-	656475	-	-	?
tert-butyl 3-oxobutanoate + NADH + H+	tert butyl 3-hydroxybutanoate + NAD+		Leifsonia sp.	-	568% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
tetracosanol + NAD+	? + NADH + H+		Equus caballus	-	immobilized HLAD shows about 55% reaction rate and free HLAD shows about 15% reaction rate with tetracosanol compared to ethanol at pH 8.8 and 30�C	697660	-	-	?
tetrahydro-4H-pyran-4-one + NADH + H+	? + NAD+		Thermus sp.	B2ZRE3	10% activity compared to cyclohexanone	695811	-	-	?
trans-4-(N,N-dimethylamino)-cinnamaldehyde + NADH	trans-4-(N,N-dimethylamino)-cinnamyl alcohol + NAD+		Homo sapiens	-	-	285574	-	-	?
trans-4-methylcyclohexanol + NAD+	4-methylcyclohexanone + NADH		Scaptodrosophila lebanonensis	-	-	285616	-	-	?
trans-cinnamaldehyde + NADH + H+	cinnamyl alcohol + NAD+		Sulfolobus solfataricus	-	-	697839	-	-	r
trans-cinnamaldehyde + NADH + H+	cinnamyl alcohol + NAD+		Leifsonia sp.	-	% of the activity with phenyl trifluoromethyl ketone	667255	-	-	?
trans-cinnamyl alcohol + NAD+	(2E)-3-phenylprop-2-enal + NADH + H+		Thermus thermophilus	-	activity is 3.9fold higher than with (S)-(-)-1-phenylethanol	684583	-	-	?
Tris + NAD+	? + NADH		Saccharomyces cerevisiae	-	-	655649	-	-	r
Triton X-100 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	7% activity compared to benzyl alcohol	678779	-	-	?
Triton X-114 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	3% activity compared to benzyl alcohol	678779	-	-	?
Triton X-165 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	24% activity compared to benzyl alcohol	678779	-	-	?
Triton X-35 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	43% activity compared to benzyl alcohol	678779	-	-	?
Triton X-405 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	19% activity compared to benzyl alcohol	678779	-	-	?
Triton X-45 + NAD+	? + NADH		Pseudomonas putida	Q76HN6	7% activity compared to benzyl alcohol	678779	-	-	?
tryptophol + NAD+	? + NADH		Homo sapiens	-	-	285569	-	-	?
vanillyl alcohol + NAD+	vanillin + NADH		Homo sapiens	-	-	285569, 285571	-	-	?
methylglyoxal + NADH	? + NADH		Petroselinum crispum	-	11.9% of the activity with acetaldehyde	285627	-	-	?
additional information	?	-	Geobacillus stearothermophilus	-	broad substrate specificity	656475	-	-	-
additional information	?	-	Saccharomyces cerevisiae	-	constitutive enzyme	285649	-	-	-
additional information	?	-	Zymomonas mobilis	-	key enzyme in ethanol production	285623	-	-	-
additional information	?	-	Candida sp.	-	one constitutive enzyme, ADH-MI and one inducible enzyme, ADH-MII	285637	-	-	-
additional information	?	-	Oncorhynchus mykiss	-	enzyme may be involved in the metabolism of dietary wax esters in salmonid fish	285614	-	-	-
additional information	?	-	Scaptodrosophila lebanonensis	-	the enzyme oxidizes alcohols to aldehydes or ketones both for detoxification and metabolic purposes	285593	-	-	-
additional information	?	-	Mesocricetus auratus	-	involvement in the development of male hamster reproductive system	285602	-	-	-
additional information	?	-	Thermomicrobium roseum	-	enzyme shows high substrate specificity towards primary aliphatic alcohols, no activity with 2-butanol, tert-butanol, isoamyl alcohol, isobutyl alcohol, 1,6-hexadiol, and mono-, di-, and triethanolamine	655262	-	-	-
additional information	?	-	Crocus sativus	-	no activity with methanol, 2-propanol, and isoamyl alcohol	654140	-	-	-
additional information	?	-	Saccharomyces cerevisiae	-	substrate specificity and stereospecificity, substrate binding pocket structure of the 3 isozymes, involving Met294, Trp57, and Trp93	655649	-	-	-
additional information	?	-	Acetobacter pasteurianus	-	substrate specificity of the 2 isozmyes with various substrates, overview, isozymes are highly specific for the (R)-stereoisomers and enantioselctive for the R(-)isomers	655058	-	-	-
additional information	?	-	Sulfolobus solfataricus	P39462	the enzyme undergoes a substantial conformational change in the apo-holo transition, accompanied by loop movements at the domain interface	654684	-	-	-
additional information	?	-	Malus x domestica	-	alcohol dehydrogenase activity may not limit alcohol supply for ester production during ripening	669022	-	-	-
additional information	?	-	Cucumis melo	-	Cm-ADH2 cannot reduce branched aldehydes	670572	-	-	-
additional information	?	-	Saccharomyces cerevisiae	-	effects of pressure on deuterium isotope effects of yeast alcohol dehydrogenase using alternative substrates	667307	-	-	-
additional information	?	-	Flavobacterium frigidimaris	Q8L3C9	no activity with methanol	668532	-	-	-
additional information	?	-	Leifsonia sp.	-	the enzyme does not act on short-chain normal alkyl alcohols, including methanol and ethanol	667255	-	-	-
additional information	?	-	Pseudomonas putida	Q76HN6	no activity towards methanol, ethanol, 1-propanol, triethylene glycol, polyethylene glycol 400, polyethylene glycol 1000, D-sorbitol, D-sorbose, formaldehyde, acetaldehyde, propionaldehyde, butyraldehyde, and valeraldehyde	678779	-	-	-
additional information	?	-	Neurospora crassa	Q9P6C8	ADH1 preferrs primary alcohols containing C3-C8 carbons to secondary alcohols such as 2-propanol and 2-butanol. ADH1 possesses specific carboxylate ester-forming activity	684614	-	-	-
additional information	?	-	Dipodascus capitatus	-	no activity detected with: N-benzyl-2-pyrrolidinone, 2-pyrrolidinone, 3-hexanone, 4-hydroxy-2-butanone, (R)-N-benzyl-3-pyrrolidinol, ethanol, 1,3-propanediol, 1-butanol, 1,4-butanediol, 1,2,3-butanetriol, 1,2,4-butanetriol, acetol, 2-phenyl-1-propanol, 3-phenyl-1-propanol, benzyl alcohol and glycerol. No activity with NADP+ or NADPH	687850	-	-	-
additional information	?	-	Thermus thermophilus	-	preference for reduction of aromatic ketones and alpha-keto esters, and poor activity on aromatic alcohols and aldehydes	684583	-	-	-
additional information	?	-	Devosia riboflavina	-	when NADH is replaced with NADPH, the reaction rate is reduced by 0.6%	688442	-	-	-
additional information	?	-	Equus caballus	-	activity is severely reduced towards aliphatic alcohols of more than 8 carbon atoms for the free enzyme, but not so with immobilized HLAD, exhibiting an activity towards C22 and C24 aliphatic alcohols higher than 50% of the highest value, obtained with C8	697660	-	-	-
additional information	?	-	Homo sapiens	-	differences in the activities of total ADH and class I ADH isoenzyme between cancer liver tissues and healthy hepatocytes may be a factor in ethanol metabolism disorders, which can intensify carcinogenesis	686331	-	-	-
additional information	?	-	Thermus sp.	B2ZRE3	TADH is a NAD(H)-dependent enzyme and shows a very broad substrate spectrum producing exclusively the (S)-enantiomer in high enantiomeric excess (more than 99%) during asymmetric reduction of ketones	695811	-	-	-
additional information	?	-	Homo sapiens	P00326, P08319	1-octanal is no substrate for isozyme ADH1C	701322	-	-	-
additional information	?	-	Homo sapiens	P00326, P08319	1-octanal is no substrate for isozyme ADH2	701322	-	-	-
additional information	?	-	Homo sapiens	P00326, P08319	1-octanal is no substrate for isozyme ADH4	701322	-	-	-
additional information	?	-	Thermus sp.	B2ZRE3	ADH exhibits a clear preference for primary alcohols and corresponding aldehydes for aliphatic substrates, in the oxidative direction activity steeply increases with chain length until 1-propanol and then decreases slightly again with growing chain length, alpha,beta-unsaturated ketones like 3-penten-2-one and cyclohexenone are not converted by ADH, almost no conversion of methanol (0.2%) and (+)-carvone (0.4%) is detected	695811	-	-	-
additional information	?	-	Euglena gracilis	B8QU18	no activity is detected using 1 mM NADP+	699249	-	-	-
additional information	?	-	Geobacillus thermoglucosidasius	Q6RS93	no activity towards methanol	699071	-	-	-
additional information	?	-	Geobacillus thermodenitrificans	A4IP64, A4ISB9	substrates are a broad range of alkyl alcohols from ethanol to 1-triacontanol	712962	-	-	-

NATURAL SUBSTRATES	NATURAL PRODUCTS	REACTION DIAGRAM	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY SUBSTRATE	LITERATURE (Substrate)	COMMENTARY PRODUCT	LITERATURE (Product)
a primary alcohol + NAD+	an aldehyde + NADH + H+		Mus musculus	-	ADH3 is involved in multiple cellular pathways, as diverse as formaldehyde detoxification, retinoid metabolism and NO homeostasis, ADH3 is considered to play only a minor role in hepatic alcohol metabolism because ethanol concentrations rarely exceed 50 mM	697214	-	-
acetaldehyde + NADH + H+	ethanol + NAD+		Saccharomyces cerevisiae	-	cells with an extra copy of ADH1 display chronological life-span extension. Antioxidant enzymes are induced in 2xADH1 cells. Strains carrying an extra ADH1 copy show extended replicative life span and increased Sir2p activity	688866	-	-
all-trans-retinol + NAD+	all-trans-retinal + NADH		Mus musculus	-	-	697214	-	-
all-trans-retinol + NAD+	all-trans-retinal + NADH		Homo sapiens	-	ADH4 might be involved in biosynthesis of retinoic acid	656058	-	-
allyl alcohol + NAD+	acrolein + NADH		Mus musculus	-	-	655233	product is toxic in mouse hepatocytes due to cell protein carbonylation following exposure to crotyl alcohol	-
crotyl alcohol + NAD+	crotonaldehyde + NADH		Mus musculus	-	-	655233	product is toxic in mouse hepatocytes due to cell protein carbonylation following exposure to crotyl alcohol	-
crotyl alcohol + NAD+	crotonaldehyde + NADH		Equus caballus	-	product is toxic in mouse hepatocytes due to cell protein carbonylation following exposure to crotyl alcohol	655233	-	-
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	-	655206	-	-
ethanol + NAD+	acetaldehyde + NADH		Natronomonas pharaonis	-	-	686626	-	-
ethanol + NAD+	acetaldehyde + NADH		Mus musculus	-	role of the major liver isoenzyme A2 in ethanol metabolism	285603	-	-
ethanol + NAD+	acetaldehyde + NADH		Equus caballus	-	plays an important role in the metabolism of ethanol	285657	-	-
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	chi-ADH plays an important role in the metabolism of long chain alcohols and aldehydes	285576	-	-
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	the anodic enzyme form may contribute significantly to alcohol elimination in man, particularly at high concentrations when the other enzyme species are saturated	285573	-	-
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	the enzyme plays a significant role in first-pass metabolism of ethanol in human	285651	-	-
ethanol + NAD+	acetaldehyde + NADH		Homo sapiens	-	enzyme is responsible for the major ethanol oxidation capacity in the body. The products acetaldehyde and NADH are responsible for the most of the toxic effects and metabolic disturbances produced by ethanol ingestion	285565	-	285565
ethanol + NAD+	acetaldehyde + NADH		Saccharomyces cerevisiae	-	rate-limiting step of the alcoholic fermentation	655741	-	-
ethanol + NAD+	acetaldehyde + NADH		Mus musculus	-	DH3 plays an important role in systemic ethanol metabolism at higher levels of blood ethanol through activation by cytoplasmic solution hydrophobicity	667832	-	-
octanol + NAD+	octanal + NADH		Mus musculus	-	-	697214	-	-
isobutyramide + NAD+	?		Homo sapiens	-	-	656058	-	-
additional information	?	-	Saccharomyces cerevisiae	-	constitutive enzyme	285649	-	-
additional information	?	-	Zymomonas mobilis	-	key enzyme in ethanol production	285623	-	-
additional information	?	-	Candida sp.	-	one constitutive enzyme, ADH-MI and one inducible enzyme, ADH-MII	285637	-	-
additional information	?	-	Oncorhynchus mykiss	-	enzyme may be involved in the metabolism of dietary wax esters in salmonid fish	285614	-	-
additional information	?	-	Scaptodrosophila lebanonensis	-	the enzyme oxidizes alcohols to aldehydes or ketones both for detoxification and metabolic purposes	285593	-	-
additional information	?	-	Mesocricetus auratus	-	involvement in the development of male hamster reproductive system	285602	-	-
additional information	?	-	Malus x domestica	-	alcohol dehydrogenase activity may not limit alcohol supply for ester production during ripening	669022	-	-
additional information	?	-	Equus caballus	-	activity is severely reduced towards aliphatic alcohols of more than 8 carbon atoms for the free enzyme, but not so with immobilized HLAD, exhibiting an activity towards C22 and C24 aliphatic alcohols higher than 50% of the highest value, obtained with C8	697660	-	-
additional information	?	-	Homo sapiens	-	differences in the activities of total ADH and class I ADH isoenzyme between cancer liver tissues and healthy hepatocytes may be a factor in ethanol metabolism disorders, which can intensify carcinogenesis	686331	-	-
additional information	?	-	Thermus sp.	B2ZRE3	TADH is a NAD(H)-dependent enzyme and shows a very broad substrate spectrum producing exclusively the (S)-enantiomer in high enantiomeric excess (more than 99%) during asymmetric reduction of ketones	695811	-	-

COFACTOR	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY	LITERATURE	IMAGE
NAD+	Cricetulus griseus	-	-	285556	2D-image
NAD+	Ctenopharyngodon idella	-	-	285557	2D-image
NAD+	Saccharomyces cerevisiae	-	-	285558, 285641, 285642, 285643, 285644, 285645, 285646, 285649, 655735, 667307, 669148, 695705, 697267, 697658, 697669, 699019	2D-image
NAD+	Kluyveromyces marxianus	-	-	285558	2D-image
NAD+	Vicia faba	-	-	285559	2D-image
NAD+	Suncus murinus	-	-	285560	2D-image
NAD+	Oryza sativa	-	-	285561, 285635	2D-image
NAD+	Najas marina	-	-	285562	2D-image
NAD+	Scaptodrosophila lebanonensis	-	-	285563, 285593, 285616, 657317	2D-image
NAD+	Drosophila melanogaster	-	-	285563, 285598, 285613, 285618, 285619, 285620	2D-image
NAD+	Drosophila simulans	-	-	285563, 285618, 285619	2D-image
NAD+	Drosophila virilis	-	-	285563, 285619	2D-image
NAD+	Drosophila funebris, Drosophila immigrans	-	-	285563	2D-image
NAD+	Mus musculus	-	-	285564, 285603, 654730, 667832, 697214, 699982	2D-image
NAD+	Homo sapiens	-	-	285565, 285566, 285567, 285568, 285569, 285570, 285571, 285572, 285573, 285574, 285575, 285576, 285577, 285578, 285608, 285651, 655197, 655206, 656058, 686331, 691867, 697802	2D-image
NAD+	Rattus norvegicus	-	-	285565, 285604, 285605, 285606	2D-image
NAD+	Saimiri sciureus	-	-	285579	2D-image
NAD+	Macaca mulatta	-	-	285580	2D-image
NAD+	Equus caballus	-	kinetics of coenzyme binding in the pH-range 10-12	285581	2D-image
NAD+	Equus caballus	-	-	285582, 285583, 285584, 285585, 285586, 285587, 285588, 285590, 285591, 285592, 285594, 285595, 285596, 285609, 285610, 285641, 285647, 285648, 285653, 285657, 654743, 655206, 668487, 697215, 697660, 697669	2D-image
NAD+	Equus caballus	-	NAD+ acts as an activator which induces an active form of the enzyme	285589	2D-image
NAD+	Equus caballus	-	preferred substrate	285597	2D-image
NAD+	Gallus gallus	-	-	285599	2D-image
NAD+	Oryctolagus cuniculus	-	-	285600, 285601	2D-image
NAD+	Mesocricetus auratus	-	-	285602, 285650	2D-image
NAD+	Saara hardwickii	-	-	285607	2D-image
NAD+	Sulfolobus solfataricus	-	-	285611, 285621, 285625, 677301, 679816, 679883, 681372, 681629, 681763, 682627, 682630, 697839	2D-image
NAD+	Naja naja	-	-	285612	2D-image
NAD+	Oncorhynchus mykiss	-	-	285614	2D-image
NAD+	Coturnix coturnix	-	-	285615	2D-image
NAD+	Drosophila melanogaster	-	NAD+-plus-acetone-induced conversion	285617	2D-image
NAD+	Zymomonas mobilis	-	-	285622, 285623	2D-image
NAD+	Chlamydomonas moewusii	-	-	285624	2D-image
NAD+	Glycine max	-	-	285626, 285635	2D-image
NAD+	Petroselinum crispum	-	-	285627	2D-image
NAD+	Camellia sinensis	-	-	285628	2D-image
NAD+	Brassica napus	-	-	285629	2D-image
NAD+	Zea mays	-	-	285630, 285631, 285635, 285652	2D-image
NAD+	Triticum turgidum	-	-	285632	2D-image
NAD+	Triticum monococcum	-	-	285633	2D-image
NAD+	Hordeum vulgare	-	-	285634	2D-image
NAD+	Avena sativa, Citrullus lanatus, Pisum sativum, Triticum aestivum	-	-	285635	2D-image
NAD+	Emericella nidulans	-	-	285636	2D-image
NAD+	Candida sp.	-	-	285637	2D-image
NAD+	Euglena longa	-	-	285638	2D-image
NAD+	Sporotrichum pulverulentum	-	-	285639	2D-image
NAD+	Meyerozyma guilliermondii	-	-	285640	2D-image
NAD+	Schizosaccharomyces pombe	-	-	285646	2D-image
NAD+	Desulfovibrio gigas	-	-	285654	2D-image
NAD+	Entamoeba histolytica	-	-	285655	2D-image
NAD+	Alligator mississippiensis	-	-	285656	2D-image
NAD+	Crocus sativus	-	-	654140	2D-image
NAD+	Geobacillus stearothermophilus	P42328	dependent on, cofactor binding mechanism and conformation from crystal structure analysis	654751	2D-image
NAD+	Acetobacter pasteurianus	-	dependent on	655058	2D-image
NAD+	Rhodococcus ruber	-	dependent on	655082	2D-image
NAD+	Thermomicrobium roseum	-	-	655262	2D-image
NAD+	Saccharomyces cerevisiae	-	cofactor binding mode	655649	2D-image
NAD+	Thermoanaerobacter brockii	-	-	655735, 697669	2D-image
NAD+	Rana perezi	-	activity with mutants G223D/T224I and G223D/T224I/H225N	656168	2D-image
NAD+	Geobacillus stearothermophilus	-	dependent on	656475	2D-image
NAD+	Aeropyrum pernix	-	the monomer consists of a catalytic and a cofactor-binding domain, the cofactor is bound between 2 domains in a cleft	656525	2D-image
NAD+	Entamoeba histolytica	-	dependent on	656604	2D-image
NAD+	Pseudomonas aeruginosa	-	-	657302	2D-image
NAD+	Escherichia coli, Hafnia alvei, Klebsiella oxytoca, Klebsiella pneumoniae, Pseudomonas aeruginosa	-	strongly preferred as cofactor	660650	2D-image
NAD+	Mucor circinelloides	-	-	667237	2D-image
NAD+	Leifsonia sp.	-	-	667255	2D-image
NAD+	Flavobacterium frigidimaris	Q8L3C9	specific for NAD+, no activity with NADP+, pro-R stereospecificity for hydrogen transfer	668532	2D-image
NAD+	Malus x domestica	-	-	669022	2D-image
NAD+	Brevibacterium sp.	-	-	669540	2D-image
NAD+	Sulfolobus solfataricus	-	dependent	678116, 678121, 680428	2D-image
NAD+	Pseudomonas putida	Q76HN6	-	678779	2D-image
NAD+	Sulfolobus sp.	P50381	dependent	680428	2D-image
NAD+	Thermus thermophilus	-	strict requirement for NAD(H) as the coenzyme. Critical role of the D37 residue in discriminating NAD(H) from NADP(H)	684583	2D-image
NAD+	Neurospora crassa	Q9P6C8	ADH1 preferrs NAD+ 205fold better than NADP+ as cofactor; ADH3 does not react with NADP+	684614	2D-image
NAD+	Thermoanaerobacter ethanolicus	Q0PH30	-	695536	2D-image
NAD+	Thermus sp.	B2ZRE3	dependent on	695811	2D-image
NAD+	Equus caballus	-	the binding of NAD+ is kinetically limited by a unimolecular isomerization (corresponding to the conformational change) that is controlled by deprotonation of the catalytic zinc-water to produce a negatively-charged zinc-hydroxide, which can attract the positively-charged nicotinamide ring	695889	2D-image
NAD+	Saccharomyces carlsbergensis	B6UQD0	-	697267	2D-image
NAD+	Anastrepha fraterculus, Anastrepha obliqua	-	-	698114	2D-image
NAD+	Geobacillus thermoglucosidasius	Q6RS93	dependent on	699071	2D-image
NAD+	Euglena gracilis	B8QU18	specific for NAD+	699249	2D-image
NAD+	Thermoplasma acidophilum	Q9HIM3	shows NAD+ as the preferred co-factor over NADP+	700124	2D-image
NAD+	Homo sapiens	P00326, P08319	;	701322	2D-image
NAD+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	NAD+ is prefered over NADP+; NADP+ is prefered over NAD+	712962	2D-image
NADH	Cricetulus griseus	-	-	285556	2D-image
NADH	Ctenopharyngodon idella	-	-	285557	2D-image
NADH	Saccharomyces cerevisiae	-	-	285558, 285641, 285642, 285643, 285644, 285645, 285646, 285649	2D-image
NADH	Kluyveromyces marxianus	-	-	285558	2D-image
NADH	Vicia faba	-	-	285559	2D-image
NADH	Suncus murinus	-	-	285560	2D-image
NADH	Oryza sativa	-	-	285561, 285635	2D-image
NADH	Najas marina	-	-	285562	2D-image
NADH	Scaptodrosophila lebanonensis	-	-	285563, 285593, 285616	2D-image
NADH	Drosophila melanogaster	-	-	285563, 285598, 285613, 285617, 285618, 285619, 285620	2D-image
NADH	Drosophila simulans	-	-	285563, 285618, 285619	2D-image
NADH	Drosophila virilis	-	-	285563, 285619	2D-image
NADH	Drosophila funebris, Drosophila immigrans	-	-	285563	2D-image
NADH	Mus musculus	-	-	285564, 285603, 654730, 697214	2D-image
NADH	Homo sapiens	-	-	285565, 285566, 285567, 285568, 285569, 285570, 285571, 285572, 285573, 285574, 285575, 285576, 285577, 285578, 285608, 285651, 656058	2D-image
NADH	Rattus norvegicus	-	-	285565, 285604, 285605, 285606	2D-image
NADH	Saimiri sciureus	-	-	285579	2D-image
NADH	Macaca mulatta	-	-	285580	2D-image
NADH	Equus caballus	-	kinetics of coenzyme binding in the pH range 10-12	285581	2D-image
NADH	Equus caballus	-	-	285582, 285583, 285584, 285585, 285586, 285587, 285588, 285589, 285590, 285591, 285592, 285594, 285595, 285596, 285609, 285610, 285641, 285647, 285648, 285653, 285657	2D-image
NADH	Equus caballus	-	preferred coenzyme	285597	2D-image
NADH	Gallus gallus	-	-	285599	2D-image
NADH	Oryctolagus cuniculus	-	-	285600, 285601	2D-image
NADH	Mesocricetus auratus	-	-	285602, 285650	2D-image
NADH	Saara hardwickii	-	-	285607	2D-image
NADH	Sulfolobus solfataricus	-	-	285611, 285621, 285625, 679816, 679883, 681372, 681763	2D-image
NADH	Naja naja	-	-	285612	2D-image
NADH	Oncorhynchus mykiss	-	-	285614	2D-image
NADH	Coturnix coturnix	-	-	285615	2D-image
NADH	Zymomonas mobilis	-	-	285622, 285623, 667340	2D-image
NADH	Chlamydomonas moewusii	-	-	285624	2D-image
NADH	Glycine max	-	-	285626, 285635	2D-image
NADH	Petroselinum crispum	-	-	285627	2D-image
NADH	Camellia sinensis	-	-	285628	2D-image
NADH	Brassica napus	-	-	285629	2D-image
NADH	Zea mays	-	-	285630, 285631, 285635, 285652	2D-image
NADH	Triticum turgidum	-	-	285632	2D-image
NADH	Triticum monococcum	-	-	285633	2D-image
NADH	Hordeum vulgare	-	-	285634	2D-image
NADH	Avena sativa, Citrullus lanatus, Pisum sativum, Triticum aestivum	-	-	285635	2D-image
NADH	Emericella nidulans	-	-	285636	2D-image
NADH	Candida sp.	-	-	285637	2D-image
NADH	Euglena longa	-	-	285638	2D-image
NADH	Sporotrichum pulverulentum	-	-	285639	2D-image
NADH	Meyerozyma guilliermondii	-	-	285640	2D-image
NADH	Schizosaccharomyces pombe	-	-	285646	2D-image
NADH	Desulfovibrio gigas	-	-	285654	2D-image
NADH	Entamoeba histolytica	-	-	285655, 655804	2D-image
NADH	Alligator mississippiensis	-	-	285656	2D-image
NADH	Crocus sativus	-	-	654140	2D-image
NADH	Acetobacter pasteurianus	-	dependent on	655058	2D-image
NADH	Rhodococcus ruber	-	dependent on	655082	2D-image
NADH	Thermomicrobium roseum	-	-	655262	2D-image
NADH	Saccharomyces cerevisiae	-	cofactor binding mode	655649	2D-image
NADH	Rana perezi	-	activity with mutants G223D/T224I and G223D/T224I/H225N	656168	2D-image
NADH	Pseudomonas aeruginosa	-	-	657302	2D-image
NADH	Rhodococcus erythropolis	-	-	658321	2D-image
NADH	Zygosaccharomyces rouxii	-	-	658565	2D-image
NADH	Acinetobacter calcoaceticus	-	-	659674	2D-image
NADH	Neurospora crassa	-	-	659773	2D-image
NADH	Leifsonia sp.	-	-	667255	2D-image
NADH	Brevibacterium sp.	-	-	669540	2D-image
NADH	Cucumis melo	-	-	670572	2D-image
NADH	Sulfolobus solfataricus	-	dependent	678363	2D-image
NADH	Thermus thermophilus	-	strict requirement for NAD(H) as the coenzyme. Critical role of the D37 residue in discriminating NAD(H) from NADP(H)	684583	2D-image
NADH	Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962	2D-image
NADP+	Equus caballus	-	also utilized as coenzyme by the SS isoenzyme	285583	2D-image
NADP+	Oryctolagus cuniculus	-	no activity as coenzyme	285600	2D-image
NADP+	Mesocricetus auratus	-	no activity as coenzyme	285602	2D-image
NADP+	Chlamydomonas moewusii	-	no activity as coenzyme	285624	2D-image
NADP+	Emericella nidulans	-	no activity as coenzyme	285636	2D-image
NADP+	Desulfovibrio gigas	-	at 1.5% of the activity with NAD+	285654	2D-image
NADP+	Saccharomyces cerevisiae, Thermoanaerobacter brockii	-	-	655735	2D-image
NADP+	Rana perezi	-	specific for, residues Gly223, Thr224, His225, Leu200, and Lys228 are involved in cofactor binding pocket formation	656168	2D-image
NADP+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	NAD+ is prefered over NADP+; NADP+ is prefered over NAD+	712962	2D-image
NADPH	Equus caballus	-	also utilized as coenzyme by the SS isoenzyme	285583	2D-image
NADPH	Emericella nidulans	-	no activity as coenzyme	285636	2D-image
NADPH	Desulfovibrio gigas	-	at 1.6% of the activity with NADH	285654	2D-image
NADPH	Rana perezi	-	specific for, residues Gly223, Thr224, His225, Leu200, and Lys228 are involved in cofactor binding pocket formation	656168	2D-image
NADPH	Leifsonia sp.	-	weak activity	667255	2D-image
NADPH	Cucumis melo	-	about 20% of the activity with NADH	670572	2D-image
NADPH	Geobacillus thermodenitrificans	A4IP64, A4ISB9	-	712962	2D-image
3-benzoylpyridine-adenine dinucleotide	Equus caballus	-	can be used as coenzyme	285588	2D-image
additional information	Scaptodrosophila lebanonensis	-	crystallographic study of the coenzyme binding mode	285593	-
additional information	Equus caballus	-	kinetics of native and modified enzyme with coenzyme analogues	285609	-
additional information	Saccharomyces cerevisiae	-	kinetic study on the binding of monomeric and polymeric derivatives of NAD+	285643	-
additional information	Brevibacterium sp.	-	NADP+ shows less than 0.1% of the activity with NAD+	669540	-

METALS and IONS	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY	LITERATURE
Co2+	Saccharomyces cerevisiae	-	construction of an active metal-substituted mutant by substituting Zn2+ for Cu2+ or Co2+, which maintain the same configuration as the native zinc ion, but possessing a wider pH range and a lower activity and substrate affinity than the wild-type enzyme, overview	655741
copper	Macaca mulatta	-	contains 0.5 mol of copper per mol of enzyme	285580
Cu2+	Saccharomyces cerevisiae	-	construction of an active metal-substituted mutant by substituting Zn2+ for Cu2+ or Co2+, which maintain the same configuration as the native zinc ion, but possessing a wider pH range and a lower activity and substrate affinity than the wild-type enzyme, overview	655741
Cu2+	Devosia riboflavina	-	1 mM CuSO4, 1.7fold activation	688442
Fe2+	Candida sp.	-	enhances activity	285637
Fe2+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 136% of initial activity; 1 mM, 168% of initial activity	712962
K+	Thermus thermophilus	-	100 mM KCl, 1.9fold activation	684583
KCl	Natronomonas pharaonis	-	most active at 5 M NaCl or 4 M KCl	686626
Li+	Thermus thermophilus	-	100 mM LiCl, 1.8fold activation	684583
Li+	Devosia riboflavina	-	1 mM LiCl, 1.1fold activation	688442
Mg2+	Candida sp.	-	enhances activity	285637
Na+	Thermus thermophilus	-	100 mM NaCl, 1.8fold activation	684583
Na+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 110% of initial activity	712962
NaCl	Natronomonas pharaonis	-	most active at 5 M NaCl or 4 M KCl	686626
Ni2+	Devosia riboflavina	-	1 mM NiSO4, 1.2fold activation	688442
Zinc	Homo sapiens	-	zinc containing enzyme	285567
Zinc	Homo sapiens	-	contains 3.8 mol of Zn per mol of protein	285571
Zinc	Homo sapiens	-	from beta1gamma1 and gamma1gamma1 isoenzyme the active-site zinc is extracted much more slowly than from beta1beta1 isoenzyme. Characterization of active-site-specific zinc-depleted and reconstituted cobalt(II) alcohol dehydrogenase	285574
Zinc	Homo sapiens	-	3.6-4.2 gatom of zinc per mol	285576
Zinc	Homo sapiens	-	contains 3.7 gatom of zinc per mol of enzyme	285578
Zinc	Saimiri sciureus	-	contains 3.9 gatom of zinc per mol of enzyme	285579
Zinc	Macaca mulatta	-	contains 3.7-4.2 mol of zinc per mol of enzyme	285580
Zinc	Equus caballus	-	substitution of catalytic and /or noncatalytic zinc ions by cobaltous ions	285591
Zinc	Equus caballus	-	contains 4 zinc atoms per molecule	285597
Zinc	Oryctolagus cuniculus	-	contains 3.8 mol of Zn per mol of protein	285600
Zinc	Mus musculus	-	isoenzyme A2 contains 2.7 mol of zinc per mol of enzyme, isoenzyme b2 contains 1.9 mol of zinc per mol of enzyme, isoenzyme C2 contains 3.2 mol of zinc per mol of enzyme. A and C subunits each contain two atoms of zinc, with at least one being involved catalytically, the b subunit probably contains a single non-catalytic zinc atom	285603
Zinc	Rattus norvegicus	-	ADH-1 contains 3.9 mol of zinc per mol of subunit, ADH-2 contains 4.2 mol of zinc per mol of subunit	285604
Zinc	Sulfolobus solfataricus	-	2 mM required for optimal activity	285621
Zinc	Zymomonas mobilis	-	enzyme form ADH I and ADH II contain one zinc atom per subunit	285622
Zinc	Chlamydomonas moewusii	-	contains 4 zinc atoms per dimer	285624
Zinc	Sulfolobus solfataricus	-	-	285625
Zinc	Zea mays	-	required for activity, tightly bound within the enzyme	285630
Zinc	Emericella nidulans	-	contains 1 zinc atom per subunit	285636
Zinc	Mesocricetus auratus	-	isoenzyme AA-ADH contains 4.3 zinc atoms per dimeric molecule, isoenzyme BB-ADH contains 3.7 zinc atoms per dimeric molecule, isoenzyme AA-ADH contains 4.1 zinc atoms per dimeric molecule	285650
Zinc	Homo sapiens	-	enzyme contains 7.59 zinc atoms per molecule	285651
Zinc	Desulfovibrio gigas	-	contains 1.2 Zn atom per subunit	285654
Zinc	Kluyveromyces marxianus	A1IIA3, A1IIA4	KmADH3 appears to belong to the zinc-containing Adh family; KmADH4 appears to belong to the zinc-containing Adh family	685652
Zn	Flavobacterium frigidimaris	Q8L3C9	the enzyme contains 2 gram-atoms Zn per subunit	668532
Zn2+	Saccharomyces cerevisiae	-	activates	285642
Zn2+	Saccharomyces cerevisiae	-	included into the crystal strcuture	654053
Zn2+	Sulfolobus solfataricus	-	the catalytic active site zinc ion is bound to Glu69 in the apoenzyme state, but not in the ternary complex state	654684
Zn2+	Homo sapiens	-	catalytic zinc	654727
Zn2+	Mus musculus	Q9QYY9	catalytic zinc ion	654730
Zn2+	Equus caballus	-	catalytic zinc ion	654743
Zn2+	Geobacillus stearothermophilus	P42328	1 catalytic zinc ion and 1 structural zinc ion per enzyme subunit	654751
Zn2+	Acetobacter pasteurianus	-	ADH I contains 1 Zn2+ per subunit, while ADH II does not contains any metal ions	655058
Zn2+	Rhodococcus ruber	-	1 tightly bound ion per subunit	655082
Zn2+	Mus musculus	-	1 catalytic and 1 structural zinc ion per subunit	655479
Zn2+	Saccharomyces cerevisiae	-	all isozymes, amino acid residues involved in zinc in binding are Cys46, Cys174, His67, Glu68, Asp49, and Thr48, binding mode	655649
Zn2+	Saccharomyces cerevisiae	-	native enzyme contains catalytic zinc ions	655741
Zn2+	Aeropyrum pernix	-	catalytic zinc ion	656525
Zn2+	Pseudomonas aeruginosa	-	1 catalytic and 1 structural zinc ion per subunit, coordination complex geometry	657302
Zn2+	Sulfolobus solfataricus	-	contains a zinc ion which is directly involved in the structural stabilization of enzyme molecule	678363
Zn2+	Sulfolobus solfataricus	-	zinc-containing enzyme	681372
Zn2+	Sulfolobus solfataricus	Q9UXF1	ADH is a putative zinc-dependent alcohol dehydrogenase	681629
Zn2+	Sulfolobus solfataricus	-	contains eight zinc atoms per tetramer	681763
Zn2+	Sulfolobus solfataricus	-	zinc-containing metalloenzyme	682627
Zn2+	Thermus thermophilus	-	1 mM ZnSO4, 1.14fold activation	684583
Zn2+	Devosia riboflavina	-	1 mM ZnSO4, 1.3fold activation	688442
Zn2+	Mus musculus	-	2 atoms are included in each 40 kDa subunit, while one of the zinc ions is considered to serve a structural function only, the other zinc ion functions as a Lewis acid and activates the substrate in the active site, which is located in a cleft between the catalytic and the coenzyme binding domain	697214
Zn2+	Equus caballus	-	zinc metalloenzyme with two zinc atoms per subunit	697215
Zn2+	Saccharomyces cerevisiae	-	contains Zn2+	699019
Zn2+	Geobacillus thermoglucosidasius	Q6RS93	dependent on	699071
Zn2+	Euglena gracilis	B8QU18	20% of activity is obtained when replacing Mg2+ with 5 mM ZnSO4	699249
Zn2+	Thermoplasma acidophilum	Q9HIM3	maximum activity is reached at 0.5 mM Zn2+,Ta1316 ADH is able to tolerate high concentrations of Zn2+	700124
Mg2+	Euglena gracilis	B8QU18	essential for activity, in the absence of Mg2+ in the kinetic assay no ADH activity is detected	699249
additional information	Thermus sp.	B2ZRE3	not stimulated by 10 mM Li+, Mg2+, Co2+, and Ca2+	695811
additional information	Thermoplasma acidophilum	Q9HIM3	Mg2+ does not have any effect on activity	700124
additional information	Geobacillus thermodenitrificans	A4IP64, A4ISB9	enzyme contains neither Fe nor other metals, and Fe is not required for the activity, although sequence analysis reveals that ADH1 belongs to the Fe-containing/activated long-chain alcohol dehydrogenases; enzyme contains neither Fe nor other metals, and Fe is not required for the activity, although sequence analysis reveals that ADH1 belongs to the Fe-containing/activated long-chain alcohol dehydrogenases	712962

INHIBITORS	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY	LITERATURE	IMAGE
1,10-phenanthroline	Ctenopharyngodon idella	-	-	285557	2D-image
1,10-phenanthroline	Homo sapiens	-	-	285569, 285576	2D-image
1,10-phenanthroline	Saimiri sciureus	-	-	285579	2D-image
1,10-phenanthroline	Macaca mulatta	-	-	285580	2D-image
1,10-phenanthroline	Oryctolagus cuniculus	-	-	285600	2D-image
1,10-phenanthroline	Mesocricetus auratus	-	mixed type inhibition	285602	2D-image
1,10-phenanthroline	Mus musculus	-	inhibition of isoenzyme A2 and C2, no inhibition of isoenzyme B2	285603	2D-image
1,10-phenanthroline	Zymomonas mobilis	-	0.2 mM, strong inhibition	285623	2D-image
1,10-phenanthroline	Chlamydomonas moewusii	-	-	285624	2D-image
1,10-phenanthroline	Zea mays	-	-	285630	2D-image
1,10-phenanthroline	Mesocricetus auratus	-	-	285650	2D-image
1,10-phenanthroline	Flavobacterium frigidimaris	Q8L3C9	1 mM, 38% inhibition	668532	2D-image
1,10-phenanthroline	Dipodascus capitatus	-	1 mM, complete inhibition	687850	2D-image
1,10-phenanthroline	Devosia riboflavina	-	1 mM, 6% inhibition	688442	2D-image
1,2-dithioglycerol	Equus caballus	-	competitive	285653	2D-image
1,2-Ethanedithiol	Equus caballus	-	competitive	285653	2D-image
1,3-propanedithiol	Equus caballus	-	competitive	285653	2D-image
1,4-Butanedithiol	Equus caballus	-	competitive	285653	2D-image
1,4-dithioerythritol	Equus caballus	-	competitive	285653	2D-image
1,4-dithiothreitol	Equus caballus	-	competitive	285653	2D-image
1-butyl-3-methylimidazolium tetrafluoroborate	Thermus thermophilus	-	2 mM, 65% inhibition	684583	2D-image
1-hydroxypyridine-2-thione	Equus caballus	-	competitive	285653	2D-image
1-thio-1-phenylmethane	Equus caballus	-	competitive	285653	2D-image
1-thioacetamide	Equus caballus	-	competitive	285653	2D-image
1-thioacetate	Equus caballus	-	competitive	285653	2D-image
1-thiobutane	Equus caballus	-	competitive	285653	2D-image
1-thioethane	Equus caballus	-	competitive	285653	2D-image
1-thioglycerol	Equus caballus	-	competitive	285653	2D-image
1-thiopropane	Equus caballus	-	competitive	285653	2D-image
1-thiosorbitol	Equus caballus	-	competitive	285653	2D-image
12-hydroxydodecanoate	Mesocricetus auratus	-	-	285602	2D-image
2,2'-Bipyridine	Homo sapiens	-	-	285569	2D-image
2,2'-Bipyridine	Macaca mulatta	-	-	285580	2D-image
2,2'-Bipyridyl	Dipodascus capitatus	-	1 mM, 78% inhibition	687850	2D-image
2,2'-Bipyridyl	Devosia riboflavina	-	1 mM, 11% inhibition	688442	2D-image
2,2'-Bipyridyl	Thermus sp.	B2ZRE3	91% relative activity at 10 mM	695811	2D-image
2,2'-dipyridyl	Oryctolagus cuniculus	-	-	285600	2D-image
2,2'-dipyridyl	Desulfovibrio gigas	-	-	285654	2D-image
2,2,2-Trifluoroethanol	Scaptodrosophila lebanonensis	-	competitive towards ethanol	285616	2D-image
2,2,2-Trifluoroethanol	Saccharomyces cerevisiae	-	-	285649	2D-image
2,2,2-Trifluoroethanol	Schizosaccharomyces pombe	Q09669	95 mM, 74% inhibition	684960	2D-image
2,4-Dinitrophenol	Devosia riboflavina	-	1 mM, complete inhibition	688442	2D-image
2-Chloroethanol	Scaptodrosophila lebanonensis	-	competitive towards ethanol	285616	2D-image
2-fluoroethanol	Saccharomyces cerevisiae	-	-	285649	2D-image
2-mercapto-1-methylimidazole	Equus caballus	-	competitive	285653	2D-image
2-mercaptobenzimidazole	Equus caballus	-	competitive	285653	2D-image
2-mercaptobenzothiazole	Equus caballus	-	competitive	285653	2D-image
2-mercaptoethanol	Triticum monococcum	-	-	285633	2D-image
2-mercaptoethanol	Equus caballus	-	competitive	285653	2D-image
2-mercaptoethanol	Devosia riboflavina	-	1 mM, 19% inhibition	688442	2D-image
2-mercaptoimidazole	Equus caballus	-	competitive	285653	2D-image
2-phenylethanethiol	Equus caballus	-	competitive	285653	2D-image
2-pyridylethanethiol	Equus caballus	-	competitive	285653	2D-image
2-thioacetate	Equus caballus	-	competitive	285653	2D-image
2-thiobutane	Equus caballus	-	competitive	285653	2D-image
2-thiopropane	Equus caballus	-	competitive	285653	2D-image
2-thiopyridine	Equus caballus	-	competitive	285653	2D-image
2-thiopyrimidine	Equus caballus	-	competitive	285653	2D-image
3-butylthiolan 1-oxide	Homo sapiens	-	dead-end inhibitor to the enzyme-cofactor complex, inhibition of oxidation reaction	655206	2D-image
3-mercapto-1,2,4-triazole	Equus caballus	-	competitive	285653	2D-image
3-thiopropionate	Equus caballus	-	competitive	285653	2D-image
4-androsten-3,17-dione	Homo sapiens	-	competitive against substrate cyclohexanone	655206	2D-image
4-bromopyrazole	Homo sapiens	-	-	285578	2D-image
4-cyanopyrazole	Homo sapiens	-	-	285578	2D-image
4-iodopyrazole	Homo sapiens	-	-	285578	2D-image
4-iodopyrazole	Sulfolobus solfataricus	-	competitive inhibitor	681763	2D-image
4-methoxypyrazole	Homo sapiens	-	1 mM, 28% inhibition	285578	2D-image
4-methoxypyrazole	Oryctolagus cuniculus	-	-	285600	2D-image
4-methoxypyrazole	Oryctolagus cuniculus	-	class I ADHs migrate towards cathode on starch gel and are very sensitive to 4-methylpyrazole inhibition, class II ADH migrates slowly towards anode and is less sensitive to 4-methylpyrazole, class II ADH migrates rapidly towards anode and is insensitive to 4-methylpyrazole	285601	2D-image
4-methoxypyrazole	Mesocricetus auratus	-	competitive	285602	2D-image
4-methoxypyrazole	Rattus norvegicus	-	0.1-10 mM, ADH-2 is practically insensitive, ADH-3 is very sensitive	285604	2D-image
4-methoxypyrazole	Rattus norvegicus	-	competitive inhibitor of all four isoenzymes	285606	2D-image
4-methoxypyrazole	Homo sapiens	-	-	285608	2D-image
4-methoxypyrazole	Saccharomyces cerevisiae	-	-	285646	2D-image
4-Methylpyrazole	Ctenopharyngodon idella	-	-	285557	2D-image
4-Methylpyrazole	Homo sapiens	-	class III enzyme is completely insensitive to inhibition	285566, 285571	2D-image
4-Methylpyrazole	Homo sapiens	-	poor inhibitor, class II isoenzyme	285569	2D-image
4-Methylpyrazole	Homo sapiens	-	no inhibition by 12 mM	285576	2D-image
4-Methylpyrazole	Homo sapiens	-	1 mM, 31% inhibition	285578	2D-image
4-Methylpyrazole	Saimiri sciureus	-	-	285579	2D-image
4-Methylpyrazole	Macaca mulatta	-	-	285580	2D-image
4-Methylpyrazole	Mesocricetus auratus	-	isoenzyme AA-ADH, BB-ADH and TT-ADH	285650	2D-image
4-Methylpyrazole	Homo sapiens	-	competitive against ethanol	285651	2D-image
4-Methylpyrazole	Equus caballus	-	-	655233	2D-image
4-Methylpyrazole	Mus musculus	-	inhibits cell protein carbonylation following exposure to crotyl alcohol	655233	2D-image
4-Methylpyrazole	Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Pseudomonas aeruginosa	-	-	660650	2D-image
4-Methylpyrazole	Sulfolobus solfataricus	-	competitive inhibitor	681763	2D-image
4-Methylpyrazole	Homo sapiens	P00326, P08319	;	701322	2D-image
4-nitropyrazole	Homo sapiens	-	-	285578	2D-image
4-octylpyrazole	Homo sapiens	-	-	285567	2D-image
4-pentylpyrazole	Homo sapiens	-	-	285567, 285578	2D-image
4-propylpyrazole	Homo sapiens	-	-	285578	2D-image
5,5'-dinitrobis(2-nitrobenzoate)	Devosia riboflavina	-	1 mM, complete inhibition	688442	-
5-beta-D-ribofuranosylnicotinamide adenine dinucleotide	Equus caballus	-	potent and specific inhibitor	285610	2D-image
5alpha-androstan-17beta-ol-3-one	Homo sapiens	-	i.e. 5alpha-dihydrotestosterone, allosteric, competitive against substrate cyclohexanone, noncompetitive against NAD+ nd ethanol	655206	2D-image
6-Thioguanine	Equus caballus	-	competitive	285653	2D-image
6-thioguanosine	Equus caballus	-	competitive	285653	2D-image
8-Amino-6-methoxyquinoline	Homo sapiens	-	-	285567	2D-image
8-hydroxyquinoline 5-sulfonic acid	Homo sapiens	-	-	285576	2D-image
8-hydroxyquinoline 5-sulfonic acid	Saimiri sciureus	-	-	285579	2D-image
acetaldehyde	Meyerozyma guilliermondii	-	linear noncompetitive inhibition	285640	2D-image
acetaldehyde	Crocus sativus	-	product inhibition, 50% inhibition at 16 mM	654140	2D-image
acetaldehyde	Thermomicrobium roseum	-	strong product inhibition	655262	2D-image
acetamide	Saccharomyces cerevisiae	-	-	285649	2D-image
acetone	Drosophila melanogaster	-	product inhibition	285598	2D-image
acetone	Picrophilus torridus	Q6L0S1	50% (v/v), 82% loss of activity	684620	2D-image
Ag+	Oryctolagus cuniculus	-	-	285600	2D-image
AgNO3	Leifsonia sp.	-	0.1 mM, 66% inhibition	667255	2D-image
AgNO3	Devosia riboflavina	-	1 mM, 37% inhibition	688442	2D-image
Al3+	Picrophilus torridus	Q6L0S1	10 mM, 30% loss of activity	684620	2D-image
Al3+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 14.7% residual activity; 1 mM, 18.9% residual activity	712962	2D-image
all-trans-retinal	Homo sapiens	-	product inhibition	656058	2D-image
all-trans-retinoic acid	Homo sapiens	-	weak feedback inhibition	656058	2D-image
Antimycin	Schizosaccharomyces pombe	Q09669	0.0017 mM, 95% inhibition	684960	2D-image
B4O72-	Zea mays	-	-	285631	-
Ba2+	Fragaria x ananassa	-	5 mM, 95% inhibition	669027	2D-image
Ba2+	Methylobacterium extorquens	-	5 mM, 94% inhibition	669027	2D-image
BaCl2	Brevibacterium sp.	-	1 mM, 95% inhibition	669540	2D-image
BaCl2	Devosia riboflavina	-	1 mM, complete inhibition	688442	2D-image
Biochanin A	Mesocricetus auratus	-	inhibition of isoenzyme BB-ADH, no inhibition of isoenzyme AA-ADH and TT-ADH	285650	2D-image
butyramide	Saccharomyces cerevisiae	-	-	285646	2D-image
Ca2+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, no residual activity	712962	2D-image
CaCl2	Thermus thermophilus	-	100 mM, 30% inhibition	684583	2D-image
caffeic acid	Mus musculus	-	mixed type of inhibition	699982	2D-image
Captopril	Equus caballus	-	competitive	285653	2D-image
CHAPS	Picrophilus torridus	Q6L0S1	10% (w/v), 59% inhibition	684620	2D-image
chromomycin A3	Saccharomyces cerevisiae	-	-	699019	2D-image
Cibacron blue	Scaptodrosophila lebanonensis	-	competitive towards NAD+	285616	2D-image
Co2+	Desulfovibrio gigas	-	-	285654	2D-image
Co2+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 51.9% residual activity; 1 mM, 68.7% residual activity	712962	2D-image
CoCl2	Dipodascus capitatus	-	1 mM, 37% inhibition	687850	2D-image
coenzyme A	Equus caballus	-	competitive	285653	2D-image
Cr3+	Fragaria x ananassa	-	5 mM, 88% loss of activity	669027	2D-image
Cr3+	Methylobacterium extorquens	-	5 mM, 84% loss of activity	669027	2D-image
Cu2+	Oryctolagus cuniculus	-	-	285600	2D-image
Cu2+	Zea mays	-	no effect	285630	2D-image
Cu2+	Candida parapsilosis	B2KJ46	1 mM, 99% loss of activity	684556	2D-image
Cu2+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 14.0% residual activity; 1 mM, 44.2% residual activity	712962	2D-image
CuCl2	Flavobacterium frigidimaris	Q8L3C9	1 mM, 68% inhibition	668532	2D-image
CuCl2	Brevibacterium sp.	-	1 mM, complete inhibition	669540	2D-image
CuCl2	Thermus thermophilus	-	1 mM, 24% inhibition	684583	2D-image
CuCl2	Dipodascus capitatus	-	1 mM, complete inhibition	687850	2D-image
cyanide	Zymomonas mobilis	-	competitive with nicotinamide nucleotides. NADH increases cyanide-resistance of ADH II	667340	2D-image
cyclobutyl carbinol	Entamoeba histolytica	-	complete inhibition in vitro at 890 nM, anti-amoebic activity on trophozoites by growth inhibition of recombinant Escherichia coli cells	655804	2D-image
cyclohexylformamide	Mus musculus	Q9QYY9	dead-end inhibition pattern	654730	2D-image
cyclopropyl carbinol	Entamoeba histolytica	-	complete inhibition in vitro at 1820 nM, anti-amoebic activity on trophozoites by growth inhibition of recombinant Escherichia coli cells	655804	2D-image
Cys	Equus caballus	-	competitive	285653	2D-image
cysteamine	Equus caballus	-	competitive	285653	2D-image
daidzein	Mesocricetus auratus	-	inhibition of isoenzyme BB-ADH, no inhibition of isoenzyme AA-ADH and TT-ADH	285650	2D-image
diethyldithiocarbamate	Equus caballus	-	competitive	285653	2D-image
Dimethyl sulfoxide	Equus caballus	-	-	685155	2D-image
dipicolinic acid	Homo sapiens	-	-	285576	2D-image
dipicolinic acid	Saimiri sciureus	-	-	285579	2D-image
dipicolinic acid	Saccharomyces cerevisiae	-	Zn2+ chelator and inhibitor of ADH	699019	2D-image
Disulfiram	Equus caballus	-	competitive	285653	2D-image
dithiothreitol	Devosia riboflavina	-	1 mM, 6% inhibition	688442	2D-image
dithiothreitol	Thermus sp.	B2ZRE3	14% relative activity at 10 mM	695811	2D-image
DMSO	Picrophilus torridus	Q6L0S1	50% (v/v), 29% loss of activity	684620	2D-image
DMSO	Homo sapiens	P00326, P08319	DMSO inhibits isozyme ADH2-catalysed oxidation in an uncompetitive mode and reduction in a mixed mode; DMSO inhibits isozymes ADH1C-catalysed oxidation in an uncompetitive mode and reduction in a mixed mode, no inhibition is detected with isozyme ADH3; DMSO inhibits isozymes ADH4-catalysed oxidation in an uncompetitive mode and reduction in a mixed mode	701322	2D-image
dodecanoic acid	Mus musculus	-	inhibits ADH3 irrespective of substrate	697214	2D-image
EDTA	Homo sapiens	-	-	285569	2D-image
EDTA	Saimiri sciureus	-	-	285579	2D-image
EDTA	Macaca mulatta	-	-	285580	2D-image
EDTA	Sulfolobus solfataricus	-	15 mM, 85% inhibition	285621	2D-image
EDTA	Zea mays	-	-	285631	2D-image
EDTA	Desulfovibrio gigas	-	-	285654	2D-image
EDTA	Acetobacter pasteurianus	-	67% inhibition of ADH II at 5 mM, 45% inhibition of ADH I at 1 mM, irreversible inhibition, addition of Mg2+ and Zn2+ increase the inhibitory effect	655058	2D-image
EDTA	Fragaria x ananassa	-	25% inhibition at 10.5 mM, 44% inhibition at 21 mM	669027	2D-image
EDTA	Methylobacterium extorquens	-	31% inhibition at 10.5 mM, 92% inhibition at 21 mM	669027	2D-image
EDTA	Sulfolobus solfataricus	-	loses 30% of its activity immediately on addition of EDTA	681763	2D-image
EDTA	Devosia riboflavina	-	1 mM, 31% inhibition	688442	2D-image
EDTA	Thermus sp.	B2ZRE3	2.3% relative activity at 10 mM	695811	2D-image
Ellagic acid	Mus musculus	-	mixed type of inhibition	699982	2D-image
ethanol	Crocus sativus	-	substrate inhibition above 0.5 M	654140	2D-image
ethanol	Picrophilus torridus	Q6L0S1	50% (v/v), 59% loss of activity	684620	2D-image
ethanol	Homo sapiens	P00326, P08319	ethanol competitively inhibits the oxidation of 1-hydroxymethylpyrene by ADH1C and ADH3; ethanol competitively inhibits the oxidation of 1-hydroxymethylpyrene by ADH4	701322	2D-image
Fe2+	Fragaria x ananassa	-	5 mM, 61% inhibition	669027	2D-image
Fe2+	Methylobacterium extorquens	-	5 mM, 48% inhibition	669027	2D-image
FeCl2	Flavobacterium frigidimaris	Q8L3C9	1 mM, 57% inhibition	668532	2D-image
FeCl3	Leifsonia sp.	-	1 mM, 34% inhibition	667255	2D-image
FeCl3	Dipodascus capitatus	-	0.1 mM, 13% inhibition	687850	2D-image
FeSO4	Devosia riboflavina	-	1 mM, complete inhibition	688442	2D-image
genistein	Mesocricetus auratus	-	inhibition of isoenzyme BB-ADH, no inhibition of isoenzyme AA-ADH and TT-ADH	285650	2D-image
Glutaraldehyde	Saccharomyces cerevisiae	-	71% relative activity in the presence of 10 mM glutaraldehyde	695705	2D-image
glutathione	Oryctolagus cuniculus	-	-	285600	2D-image
glutathione	Triticum monococcum	-	-	285633	2D-image
glutathione	Equus caballus	-	competitive	285653	2D-image
Guanidine hydrochloride	Sulfolobus solfataricus	-	-	678121	2D-image
H2O2	Equus caballus	-	inactivation is caused by oxidation of its functional Cys residues, coenzyme protects from inactivation	285595	2D-image
H2O2	Saccharomyces cerevisiae	-	-	688657	2D-image
heptafluorobutanol	Saccharomyces cerevisiae	-	-	285646	2D-image
heptane	Picrophilus torridus	Q6L0S1	50% (v/v), 99% loss of activity	684620	2D-image
hexadecane	Picrophilus torridus	Q6L0S1	50% (v/v), 71% loss of activity	684620	2D-image
hexadecyltrimethyl-ammonium bromide	Flavobacterium frigidimaris	Q8L3C9	1 mM, 79% inhibition	668532	2D-image
Hg2+	Oryctolagus cuniculus	-	-	285600	2D-image
Hg2+	Zea mays	-	no effect	285630	2D-image
Hg2+	Sulfolobus solfataricus	-	-	681763	2D-image
HgCl2	Leifsonia sp.	-	0.1 mM, 85% inhibition	667255	2D-image
HgCl2	Flavobacterium frigidimaris	Q8L3C9	1 mM, complete inhibition	668532	2D-image
HgCl2	Brevibacterium sp.	-	1 mM, complete inhibition	669540	2D-image
HgCl2	Thermus thermophilus	-	1 mM, 67% inhibition	684583	2D-image
HgCl2	Dipodascus capitatus	-	1 mM, complete inhibition	687850	2D-image
HgCl2	Devosia riboflavina	-	1 mM, complete inhibition	688442	2D-image
Hydroxylamine hydrochloride	Flavobacterium frigidimaris	Q8L3C9	1 mM, 34% inhibition	668532	2D-image
imidazole	Scaptodrosophila lebanonensis	-	pure competitive inhibition towards ethanol and (R)-(+)-phenylethanol	285616	2D-image
imidazole	Thermomicrobium roseum	-	weak inhibition	655262	2D-image
imidazole	Geobacillus stearothermophilus	-	-	656475	2D-image
Iodine	Sulfolobus solfataricus	-	-	681763	2D-image
iodoacetamide	Chlamydomonas moewusii	-	-	285624	2D-image
iodoacetamide	Zea mays	-	-	285630, 285631	2D-image
iodoacetic acid	Oryctolagus cuniculus	-	-	285600	2D-image
iodoacetic acid	Meyerozyma guilliermondii	-	-	285640	2D-image
iodoacetic acid	Flavobacterium frigidimaris	Q8L3C9	1 mM, 96% inhibition	668532	2D-image
iodoacetic acid	Dipodascus capitatus	-	1 mM, 10% inhibition	687850	2D-image
isoburyramide	Scaptodrosophila lebanonensis	-	competitive towards ethanol and butan-2-ol	285616	2D-image
Isobutyramide	Homo sapiens	-	substrate inhibition, competitive against retinol, noncompetitive against NADH	656058	2D-image
Isobutyramide	Equus caballus	-	-	685155	2D-image
isooctane	Picrophilus torridus	Q6L0S1	50% (v/v), 98% loss of activity	684620	2D-image
Isopropanol	Picrophilus torridus	Q6L0S1	50% (v/v), 88% loss of activity	684620	2D-image
K+	Picrophilus torridus	Q6L0S1	10 mM, 29% loss of activity	684620	2D-image
K+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 70.3% residual activity; 1 mM, 82.3% residual activity	712962	2D-image
KCN	Leifsonia sp.	-	1 mM, 41% inhibition	667255	2D-image
Li+	Fragaria x ananassa	-	5 mM, 32% inhibition	669027	2D-image
Li+	Methylobacterium extorquens	-	5 mM, 28% inhibition	669027	2D-image
methanol	Picrophilus torridus	Q6L0S1	50% (v/v), 30% loss of activity	684620	2D-image
Mg2+	Zea mays	-	-	285631	2D-image
Mg2+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 0.3% residual activity; 1 mM, 74.3% residual activity	712962	2D-image
MgCl2	Thermus thermophilus	-	100 mM, 33% inhibition	684583	2D-image
MgCl2	Dipodascus capitatus	-	1 mM, 10% inhibition	687850	2D-image
mithramycin	Saccharomyces cerevisiae	-	-	699019	2D-image
Mn2+	Desulfovibrio gigas	-	-	285654	2D-image
N-1-methylheptylformamide	Homo sapiens	-	inhibits isozyme gamma(2)gamma(2)	654727	2D-image
N-benzylformamide	Homo sapiens	-	inhibits isozyme beta(1)beta(1)	654727	2D-image
N-cyclopentyl-N-cyclobutylformamide	Homo sapiens	-	inhibits isozyme alphaalpha, complex structure	654727	2D-image
N-ethylmaleimide	Devosia riboflavina	-	1 mM, 11% inhibition	688442	2D-image
N-heptylformamide	Homo sapiens	-	inhibits isozyme beta(1)beta(1)	654727	2D-image
Na+	Picrophilus torridus	Q6L0S1	10 mM, 13% loss of activity	684620	2D-image
NaCN	Saccharomyces cerevisiae	-	-	285649	2D-image
NAD+	Crocus sativus	-	substrate inhibition above 5 mM	654140	2D-image
NADH	Drosophila melanogaster	-	-	285598	2D-image
NADH	Scaptodrosophila lebanonensis	-	competitive towards NAD+	285616	2D-image
NADH	Drosophila melanogaster	-	competitive towards NAD+	285618	2D-image
NADH	Meyerozyma guilliermondii	-	linear competitive inhibition	285640	2D-image
NADP+	Homo sapiens	-	-	285576	2D-image
NaN3	Chlamydomonas moewusii	-	-	285624	2D-image
NEM	Oryctolagus cuniculus	-	-	285600	2D-image
NEM	Zea mays	-	-	285630	2D-image
NEM	Desulfovibrio gigas	-	-	285654	2D-image
NEM	Flavobacterium frigidimaris	Q8L3C9	1 mM, complete inhibition	668532	2D-image
Ni2+	Desulfovibrio gigas	-	-	285654	2D-image
Ni2+	Picrophilus torridus	Q6L0S1	10 mM, 46% loss of activity	684620	2D-image
Ni2+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 18.2% residual activity; 1 mM, 72.7% residual activity	712962	2D-image
NiCl2	Flavobacterium frigidimaris	Q8L3C9	1 mM, 79% inhibition	668532	2D-image
NiCl2	Brevibacterium sp.	-	1 mM, 93% inhibition	669540	2D-image
NiCl2	Dipodascus capitatus	-	1 mM, complete inhibition	687850	2D-image
NO	Equus caballus	-	Cys residues contained within the zinc/thiolate active center may be primary sites of NO interaction	285657	2D-image
o-phenanthroline	Sulfolobus solfataricus	-	loses 30% of its activity immediately on addition of o-phenanthroline	681763	2D-image
Octanoic acid	Equus caballus	-	competitive inhibition of the hydrolysis of p-nitrophenyl octanoate	285594	2D-image
Octanoic acid	Mus musculus	Q9QYY9	dead-end inhibition pattern	654730	2D-image
Octanoic acid	Aeropyrum pernix	-	interacts with the catalytic zinc ion, binding structure	656525	2D-image
p-chloromercuribenzene sulfonate	Desulfovibrio gigas	-	-	285654	2D-image
p-hydroxymercuribenzoate	Zea mays	-	-	285630	2D-image
p-nitrophenol	Equus caballus	-	noncompetitive inhibition of the hydrolysis of p-nitrophenyl octanoate	285594	2D-image
Pb2+	Fragaria x ananassa	-	5 mM, 96% inhibition	669027	2D-image
Pb2+	Methylobacterium extorquens	-	5 mM, 98% inhibition	669027	2D-image
PbCl2	Leifsonia sp.	-	1 mM, 63% inhibition	667255	2D-image
PbCl2	Brevibacterium sp.	-	1 mM, 24% inhibition	669540	2D-image
PbCl2	Devosia riboflavina	-	1 mM, complete inhibition	688442	2D-image
PCMB	Oryctolagus cuniculus	-	-	285600	2D-image
PCMB	Zymomonas mobilis	-	-	285623	2D-image
PCMB	Zea mays	-	-	285630	2D-image
PCMB	Zea mays	-	no effect	285631	2D-image
PCMB	Meyerozyma guilliermondii	-	-	285640	2D-image
PCMB	Desulfovibrio gigas	-	-	285654	2D-image
PCMB	Flavobacterium frigidimaris	Q8L3C9	1 mM, complete inhibition	668532	2D-image
PCMB	Brevibacterium sp.	-	1 mM, complete inhibition	669540	2D-image
PCMB	Dipodascus capitatus	-	0.1 mM, complete inhibition	687850	2D-image
pefabloc	Picrophilus torridus	Q6L0S1	10 mM, 32% inhibition	684620	2D-image
Penicillamine	Equus caballus	-	competitive	285653	2D-image
PMSF	Zea mays	-	-	285630	2D-image
polyoxyethylene octylphenyl ether	Flavobacterium frigidimaris	Q8L3C9	1 mM, 43% inhibition	668532	-
pyrazole	Homo sapiens	-	0.05 mM, 50% inhibition	285565	2D-image
pyrazole	Rattus norvegicus	-	0.05 mM, complete inhibition	285565	2D-image
pyrazole	Homo sapiens	-	-	285567	2D-image
pyrazole	Homo sapiens	-	no inhibition at 1.0 mM	285578	2D-image
pyrazole	Saimiri sciureus	-	organism has a pyrazole-sensitive isoenzyme and a pyrazole-insensitive enzyme	285579	2D-image
pyrazole	Macaca mulatta	-	organism has a pyrazole-sensitive isoenzyme and a pyrazole-insensitive enzyme	285580	2D-image
pyrazole	Scaptodrosophila lebanonensis	-	competitive	285593	2D-image
pyrazole	Oryctolagus cuniculus	-	-	285600	2D-image
pyrazole	Mus musculus	-	inhibition of isoenzyme A2 and C2. Isoenzyme B2 is insensitive to pyrazole inhibition with trans-2-hexen-1-ol as substrate	285603	2D-image
pyrazole	Rattus norvegicus	-	0.1-10 mM, ADH-2 is practically insensitive, ADH-3 is very sensitive	285604	2D-image
pyrazole	Coturnix coturnix	-	pyrazole-sensitive enzyme forms ADH-1, ADH-2, ADH-3 and the pyrazole-insensitive form ADH-An	285615	2D-image
pyrazole	Scaptodrosophila lebanonensis	-	competitive towards ethanol	285616	2D-image
pyrazole	Glycine max	-	-	285626	2D-image
pyrazole	Saccharomyces cerevisiae	-	-	285649	2D-image
pyrazole	Thermomicrobium roseum	-	strong inhibition	655262	2D-image
pyrazole	Sulfolobus solfataricus	-	competitive inhibitor	681763	2D-image
pyrazole	Mus musculus	-	-	699982	2D-image
Pyridine	Thermomicrobium roseum	-	-	655262	2D-image
Pyridine	Geobacillus stearothermophilus	-	-	656475	2D-image
pyridoxal 5'-phosphate	Vicia faba	-	inactivates by modifying its epsilon-amino group, NAD+ protects	285559	2D-image
S-2-Chloro-3-(imidazol-5-yl)propionate	Equus caballus	-	inactivation at pH 8.2, R-2-chloro-3-(imidazol-5-yl)propionate has no effect	285584	2D-image
SDS	Flavobacterium frigidimaris	Q8L3C9	1 mM, 91% inhibition	668532	2D-image
SDS	Picrophilus torridus	Q6L0S1	10% (w/v), 95% inhibition	684620	2D-image
SDS	Saccharomyces cerevisiae	-	in the presence of the surfactant the initial reaction rates are consistently lower than in pure buffer at all the surfactant concentrations considered (0.5-50 mM). This effect is mainly due to an increase in the dissociation constant of beta-NAD+ which reaches its maximum value (7.1 mM) at the critical micelle concentration. Above the critical micelle concentration the effect of the surfactant is mainly due to an increase in the Michaels constants of the alcohol, with values of 41 mM for 15 mM SDS and 50 mM for 50 mM SDS	689887	2D-image
SDS	Thermus sp.	B2ZRE3	0.4% relative activity at 10% (v/v)	695811	2D-image
sodium dodecylsulfate	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 3% residual activity; 1 mM, no residual activity	712962	2D-image
sodium iodoacetate	Sulfolobus solfataricus	-	increasing concentrations od sodium iodoacetate produce a slight decrease in activity	678116	2D-image
sulfonic acid	Homo sapiens	-	-	285576	2D-image
syringaldehyde	Mus musculus	-	mixed type of inhibition	699982	2D-image
tert-butanol	Picrophilus torridus	Q6L0S1	50% (v/v), 92% loss of activity	684620	2D-image
tert-butyl hydroperoxide	Saccharomyces cerevisiae	-	irreversible, inactivation is associated with -SH group oxidation	285641	2D-image
testosterone	Mesocricetus auratus	-	inhibition of isoenzyme BB-ADH, no inhibition of isoenzyme AA-ADH and TT-ADH	285650	2D-image
Thiophenol	Equus caballus	-	competitive	285653	2D-image
Thiourea	Equus caballus	-	competitive	285653	2D-image
Toluene	Picrophilus torridus	Q6L0S1	50% (v/v), 97% loss of activity	684620	2D-image
trichloroethanol	Thermomicrobium roseum	-	weak inhibition	655262	2D-image
trifluoroethanol	Saccharomyces cerevisiae	-	-	285646	2D-image
trifluoroethanol	Homo sapiens	-	competitive against retinol, noncompetitive against NAD+	656058	2D-image
Triton X-100	Picrophilus torridus	Q6L0S1	10% (w/v), 78% inhibition	684620	2D-image
Tween 20	Picrophilus torridus	Q6L0S1	10% (w/v), 82% inhibition	684620	2D-image
Tween 80	Homo sapiens	-	competitive, stabilizes the retinoid compounds, elevates the Km values of the substrates, most effective at 0.1% w/v	654370	2D-image
Tween 80	Picrophilus torridus	Q6L0S1	10% (w/v), 89% inhibition	684620	2D-image
Tween 80	Thermus sp.	B2ZRE3	13% relative activity at 10% (v/v)	695811	2D-image
Urea	Picrophilus torridus	Q6L0S1	5 M, 41% inhibition	684620	2D-image
Urea	Thermus sp.	B2ZRE3	1% relative activity at 5 M	695811	2D-image
Vanillin	Mus musculus	-	mixed type of inhibition	699982	2D-image
Zn2+	Oryctolagus cuniculus	-	-	285600	2D-image
Zn2+	Zea mays	-	-	285631	2D-image
Zn2+	Candida sp.	-	0.1 mM, 20% decrease of activity	285637	2D-image
Zn2+	Desulfovibrio gigas	-	-	285654	2D-image
Zn2+	Fragaria x ananassa	-	5 mM, 17% loss of activity	669027	2D-image
Zn2+	Methylobacterium extorquens	-	5 mM, 29% loss of activity	669027	2D-image
Zn2+	Natronomonas pharaonis	-	-	686626	2D-image
Zn2+	Thermus sp.	B2ZRE3	91% relative activity at 10 mM	695811	2D-image
Zn2+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 14.1% residual activity; 1 mM, 30.5% residual activity	712962	2D-image
ZnSO4	Dipodascus capitatus	-	1 mM, complete inhibition	687850	2D-image
Zr2+	Fragaria x ananassa	-	5 mM, 72% inhibition	669027	2D-image
Zr2+	Methylobacterium extorquens	-	5 mM, 78% inhibition	669027	2D-image
Mn2+	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 14.3% residual activity; 1 mM, 23.4% residual activity	712962	2D-image
additional information	Equus caballus	-	design of inhibitors	285586	-
additional information	Avena sativa, Citrullus lanatus, Glycine max, Oryza sativa, Pisum sativum, Triticum aestivum, Zea mays	-	inactivator from rice seedlings	285635	-
additional information	Saccharomyces cerevisiae	-	use of competitive dead-end inhibitors to determine the chemical mechanism of action of yeast alcohol dehydrogenase	285649	-
additional information	Equus caballus	-	thiols and dithiols have their main effect, at the enzyme-NAD+-thiol complex level, by competition with alcohol for the catalytic zinc	285653	-
additional information	Hafnia alvei	-	no inhibition by 4-methylpyrazole	660650	-
additional information	Sulfolobus solfataricus	-	not affected by Cu2+	681763	-

ACTIVATING COMPOUND	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY	LITERATURE	IMAGE
Acetylsalicylate	Equus caballus	-	enhances activity	668487	2D-image
butyramide	Mus musculus	-	activates ADH3	667832	2D-image
capronamide	Mus musculus	-	activates ADH3	667832	2D-image
EDTA	Candida sp.	-	enhances activity	285637	2D-image
EDTA	Thermus thermophilus	-	10 mM, 1.65fold activation	684583	2D-image
EDTA	Geobacillus thermodenitrificans	A4IP64, A4ISB9	1 mM, 105% of initial activity	712962	2D-image
Glutaraldehyde	Saccharomyces cerevisiae	-	treating with 0.5% glutaraldehyde solution, the activity of the immobilized enzyme is at maximum	695705	2D-image
iodoacetamide	Sulfolobus solfataricus	-	1 mM activates up to 25fold	681763	2D-image
S-nitrosoglutathione	Mus musculus	-	ADH3-mediated alcohol oxidation is promoted in the presence of S-nitrosoglutathione	697214	2D-image
tert-butanol	Mus musculus	-	activates ADH3	667832	2D-image
tert-butyl hydroperoxide	Equus caballus	-	stimulation up to 100 mM	285641	2D-image
Triton X-100	Thermus sp.	B2ZRE3	201% relative activity at 10% (v/v)	695811	2D-image
Urea	Thermus sp.	B2ZRE3	130% relative activity at 1 M	695811	2D-image
Valeramide	Mus musculus	-	activates ADH3	667832	2D-image
iodoacetate	Devosia riboflavina	-	1 mM, 1.1fold activation	688442	2D-image
additional information	Equus caballus	-	isonicotinimidylation and methylation increases activity	285590	-

KM VALUE [mM]	KM VALUE [mM] Maximum	SUBSTRATE	ORGANISM	UNIPROT ACCESSION NO.	COMMENTARY	LITERATURE	IMAGE
0.25	-	(+)-2-methylcyclohexanone	Sulfolobus solfataricus	-	-	285621	-
0.41	-	(R)-2-butanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
7.5	-	(R)-2-butanol	Equus caballus	-	-	285586	2D-image
37.4	-	(R)-2-butanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
1.92	-	(R)-2-octanol	Equus caballus	-	-	285586	2D-image
0.22	-	(R)-2-pentanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
11.7	-	(R)-2-pentanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
31.7	-	(R)-2-pentanol	Equus caballus	-	-	285586	2D-image
0.02	-	(R)-2-phenylpropanol	Brevibacterium sp.	-	-	669540	2D-image
4.2	-	(S)-(+)-1-indanol	Thermus thermophilus	-	65�C	684583	2D-image
4.2	-	(S)-(+)-alpha-tetraol	Thermus thermophilus	-	65�C	684583	2D-image
18.1	-	(S)-(-)-1-phenylethanol	Thermus thermophilus	-	65�C	684583	2D-image
0.012	-	(S)-2-butanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
1.35	-	(S)-2-butanol	Equus caballus	-	-	285586	2D-image
29.8	-	(S)-2-butanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
120	-	(S)-2-butanol	Homo sapiens	-	-	285608	2D-image
0.18	-	(S)-2-octanol	Equus caballus	-	-	285586	2D-image
0.07	-	(S)-2-pentanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.73	-	(S)-2-pentanol	Equus caballus	-	-	285586	2D-image
8.8	-	(S)-2-pentanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.157	-	(S)-2-phenylpropanol	Brevibacterium sp.	-	-	669540	2D-image
8.47	-	(S)-N-benzyl-3-pyrrolidinol	Dipodascus capitatus	-	pH 8.0	687850	2D-image
1.65	-	1,2-Propanediol	Methylobacterium extorquens	-	-	669027	2D-image
15.84	-	1,2-Propanediol	Fragaria x ananassa	-	-	669027	2D-image
0.08	-	1-butanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.17	-	1-butanol	Rattus norvegicus	-	isoenzyme ADH-3, pH 10.0	285604	2D-image
1.6	-	1-butanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
17	-	1-butanol	Rattus norvegicus	-	isoenzyme ADH-1, pH 10.0	285604	2D-image
19.93	-	1-butanol	Fragaria x ananassa	-	-	669027	2D-image
25.78	-	1-butanol	Methylobacterium extorquens	-	-	669027	2D-image
230	-	1-butanol	Rattus norvegicus	-	isoenzyme ADH-1, pH 7.5	285604	2D-image
3.6e-05	-	1-formyl-6-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	2D-image
0.00032	-	1-formyl-6-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	2D-image
0.0009	-	1-formyl-6-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	2D-image
0.0038	-	1-formyl-6-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	2D-image
3.5e-05	-	1-formyl-8-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	2D-image
0.00024	-	1-formyl-8-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	2D-image
0.00131	-	1-formyl-8-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	2D-image
0.00149	-	1-formyl-8-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	2D-image
0.0005	-	1-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	2D-image
0.00055	-	1-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	2D-image
0.00092	-	1-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	2D-image
0.012	-	1-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	2D-image
0.038	-	1-Heptanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.21	-	1-Heptanol	Sulfolobus solfataricus	-	mutant enzyme W95L, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.67	-	1-Heptanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.035	-	1-Hexanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.04	-	1-Hexanol	Sulfolobus solfataricus	-	mutant enzyme W95L, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.88	-	1-Hexanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.00028	-	1-hydroxymethyl-6-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	-
0.00057	-	1-hydroxymethyl-6-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	-
0.00115	-	1-hydroxymethyl-6-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	-
0.0064	-	1-hydroxymethyl-6-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	-
0.00031	-	1-hydroxymethyl-8-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	-
0.0016	-	1-hydroxymethyl-8-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	-
0.0064	-	1-hydroxymethyl-8-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	-
0.059	-	1-hydroxymethyl-8-methylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	-
0.00059	-	1-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	2D-image
0.00075	-	1-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	2D-image
0.0283	-	1-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	2D-image
0.076	-	1-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	2D-image
5.1	-	1-Indanol	Thermus thermophilus	-	65�C	684583	2D-image
27.6	-	1-Indanone	Thermus thermophilus	-	65�C	684583	2D-image
0.025	-	1-Octanol	Rattus norvegicus	-	isoenzyme ADH-3, pH 10.0	285604	2D-image
0.1	-	1-Octanol	Rattus norvegicus	-	isoenzyme ADH-2	285604	2D-image
0.39	-	1-Octanol	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	2D-image
0.5	-	1-Octanol	Rattus norvegicus	-	isoenzyme ADH-1, pH 7.5	285604	2D-image
0.51	-	1-Octanol	Rattus norvegicus	-	isoenzyme ADH-2, pH 10.0	285604	2D-image
0.55	-	1-Octanol	Homo sapiens	-	-	285566	2D-image
3.88	-	1-Octanol	Geobacillus thermodenitrificans	A4IP64, A4ISB9	cosubstrate NADP+, pH 8.0, 60�C	712962	2D-image
0.027	-	1-Pentanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.08	-	1-Pentanol	Rattus norvegicus	-	isoenzyme ADH-3, pH 10.0	285604	2D-image
0.26	-	1-Pentanol	Sulfolobus solfataricus	-	mutant enzyme W95L, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
1.9	-	1-Pentanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
3.1	-	1-Pentanol	Rattus norvegicus	-	isoenzyme ADH-1, pH 10.0	285604	2D-image
27	-	1-Pentanol	Homo sapiens	-	-	285566	2D-image
78	-	1-Pentanol	Rattus norvegicus	-	isoenzyme ADH-2, pH 10.0	285604	2D-image
5.9	-	1-phenyl-1,2-propanedione	Thermus thermophilus	-	65�C	684583	2D-image
0.025	-	1-phenylethanol	Brevibacterium sp.	-	-	669540	2D-image
0.24	-	1-Propanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.33	-	1-Propanol	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
0.33	-	1-Propanol	Sulfolobus solfataricus	-	in the presence of 3 mM NAD+, in 0.1 M glycine-NaOH, pH 9.2, at 65�C	681763	2D-image
0.6	-	1-Propanol	Sulfolobus solfataricus	-	wild type enzyme, at 65�C	678121	2D-image
1.7	-	1-Propanol	Sulfolobus solfataricus	-	mutant enzyme N249Y, at 65�C	678121	2D-image
2.4	-	1-Propanol	Sulfolobus solfataricus	-	carboxymethylated enzyme, at 55�C	678116	2D-image
3.09	-	1-Propanol	Methylobacterium extorquens	-	-	669027	2D-image
3.54	-	1-Propanol	Fragaria x ananassa	-	-	669027	2D-image
6.5	-	1-Propanol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.2	-	11-cis-retinal	Equus caballus	-	reduction with NADH	285648	2D-image
0.018	-	11-cis-retinol	Homo sapiens	-	isozyme ADH1B2, pH 7.5, 25�C	655479	2D-image
0.035	-	11-cis-retinol	Homo sapiens	-	isozyme ADH1B1, pH 7.5, 25�C	655479	2D-image
0.28	-	11-cis-retinol	Equus caballus	-	oxidation with NAD+	285648	2D-image
0.013	-	12-hydroxydodecanoate	Rattus norvegicus	-	isoenzyme ADH-3, pH 10.0	285604	2D-image
0.02	-	12-hydroxydodecanoate	Mesocricetus auratus	-	isoenzyme BB-ADH	285650	2D-image
0.04	-	12-hydroxydodecanoate	Coturnix coturnix	-	enzyme form ADH-3	285615	2D-image
0.047	-	12-hydroxydodecanoate	Homo sapiens	-	-	285651	2D-image
0.048	-	12-hydroxydodecanoate	Homo sapiens	-	-	285608	2D-image
0.05	-	12-hydroxydodecanoate	Mesocricetus auratus	-	isoenzyme BB-ADH and isoenzyme ADH-TT	285650	2D-image
0.06	-	12-hydroxydodecanoate	Mesocricetus auratus	-	isoenzyme AA-ADH	285650	2D-image
0.1	-	12-hydroxydodecanoate	Homo sapiens	-	-	285571	2D-image
0.1	-	12-hydroxydodecanoate	Rattus norvegicus	-	isoenzyme ADH-1, pH 10.0	285604	2D-image
0.23	-	12-hydroxydodecanoate	Homo sapiens	-	-	285569	2D-image
1.4	-	12-hydroxydodecanoate	Rattus norvegicus	-	isoenzyme ADH-1, pH 10.0	285604	2D-image
2.3	-	12-hydroxydodecanoate	Mesocricetus auratus	-	isoenzyme TT-ADH	285650	2D-image
0.056	-	12-Hydroxydodecanoic acid	Homo sapiens	-	-	285566	2D-image
0.11	-	13-cis-retinal	Equus caballus	-	oxidation with NAD+	285648	2D-image
0.137	-	13-cis-retinal	Equus caballus	-	reduction with NADH	285648	2D-image
0.257	-	13-cis-retinol	Equus caballus	-	oxidation with NAD+	285648	2D-image
0.06	-	16-hydroxyhexadecanoate	Homo sapiens	-	-	285569	2D-image
11.2	-	2,2,2-trifluoroacetophenone	Thermus thermophilus	-	65�C	684583	2D-image
11.9	-	2-butanol	Corynebacterium glutamicum R	-	33�C, pH 8	684612	2D-image
15	-	2-Butanone	Equus caballus	-	-	285586	2D-image
0.35	-	2-Buten-1-ol	Rattus norvegicus	-	isoenzyme ADH-3, pH 10.0	285604	2D-image
2.5	-	2-Buten-1-ol	Rattus norvegicus	-	isoenzyme ADH-1, pH 10.0	285604	2D-image
60	-	2-Buten-1-ol	Rattus norvegicus	-	isoenzyme ADH-2, pH 10.0	285604	2D-image
310	-	2-deoxy-D-ribose	Homo sapiens	-	-	285569	2D-image
0.25	-	2-ethoxyethanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	-
0.0021	-	2-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	2D-image
0.0029	-	2-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	2D-image
0.0069	-	2-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	2D-image
0.009	-	2-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	2D-image
0.00048	-	2-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	-
0.0044	-	2-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	-
0.033	-	2-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	-
0.106	-	2-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	-
0.021	-	2-Methylcyclohexanol	Sulfolobus solfataricus	-	-	285621	2D-image
2.7	-	2-methylpropan-1-ol	Scaptodrosophila lebanonensis	-	-	285616	2D-image
14.2	-	2-Pentanone	Equus caballus	-	-	285586	2D-image
0.864	-	2-phenylpropionaldehyde	Brevibacterium sp.	-	-	669540	2D-image
0.6	-	2-Propanol	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
0.6	-	2-Propanol	Sulfolobus solfataricus	-	in the presence of 3 mM NAD+, in 0.1 M glycine-NaOH, pH 9.2, at 65�C	681763	2D-image
1.1	-	2-Propanol	Scaptodrosophila lebanonensis	-	-	285616	2D-image
3.42	-	2-Propanol	Methylobacterium extorquens	-	-	669027	2D-image
11.46	-	2-Propanol	Fragaria x ananassa	-	-	669027	2D-image
19.6	-	2-Propanol	Corynebacterium glutamicum R	-	33�C, pH 8	684612	2D-image
53	-	2-Propanol	Sulfolobus solfataricus	-	carboxymethylated enzyme, at 55�C	678116	2D-image
57.5	-	2-Propanol	Leifsonia sp.	-	25�C, pH 7.0	667255	2D-image
268	-	2-Propanol	Equus caballus	-	wilde-type enzyme ADh1	285647	2D-image
560	-	2-Propanol	Homo sapiens	-	-	285569	2D-image
0.025	-	3,4-dihydro-retinal	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B2	654370	2D-image
0.026	-	3,4-dihydro-retinal	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH4	654370	2D-image
0.024	-	3,4-dihydro-retinol	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B2	654370	2D-image
0.028	-	3,4-dihydro-retinol	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH4	654370	2D-image
0.14	-	3-bromobenzyl alcohol	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
0.9	-	3-bromobenzyl alcohol	Sulfolobus solfataricus	-	carboxymethylated enzyme, at 55�C	678116	2D-image
0.14	-	3-bromobenzylalcohol	Sulfolobus solfataricus	-	in the presence of 3 mM NAD+, in 0.1 M glycine-NaOH, pH 9.2, at 65�C	681763	2D-image
4.4	-	3-Methoxybenzaldehyde	Thermus thermophilus	-	65�C	684583	2D-image
1.2	-	3-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
3.3	-	3-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	carboxymethylated enzyme, at 55�C	678116	2D-image
1.2	-	3-methoxybenzylalcohol	Sulfolobus solfataricus	-	in the presence of 3 mM NAD+, in 0.1 M glycine-NaOH, pH 9.2, at 65�C; in the presence of 5 mM benzylalcohol, in 0.1 M glycine-NaOH, pH 9.2, at 65�C	681763	2D-image
7.5	-	3-methylbutan-2-one	Sulfolobus solfataricus	-	-	285621	2D-image
0.031	-	3-oxo-5beta-androstan-17beta-ol	Equus caballus	-	-	285597	2D-image
0.27	-	3-Pentanol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
1.6	-	3-Pentanol	Equus caballus	-	-	285586	2D-image
75	-	3-Pentanone	Equus caballus	-	-	285586	2D-image
0.032	-	3-Phenyl-1-propanol	Homo sapiens	-	-	285569	2D-image
0.033	-	3-phenylpropanol	Brevibacterium sp.	-	-	669540	2D-image
0.128	-	3beta,12alpha-dihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 2	285606	2D-image
0.16	-	3beta,12alpha-dihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 3	285606	2D-image
0.248	-	3beta,12alpha-dihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 4	285606	2D-image
0.31	-	3beta,12alpha-dihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme I	285606	2D-image
0.149	-	3beta,7alpha,12alpha-trihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme I	285606	2D-image
0.16	-	3beta,7alpha,12alpha-trihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 2	285606	2D-image
0.182	-	3beta,7alpha,12alpha-trihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 3	285606	2D-image
0.35	-	3beta,7alpha-12alpha-trihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 4	285606	2D-image
0.032	-	3beta-7alpha-dihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 3	285606	2D-image
0.064	-	3beta-7alpha-dihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 2	285606	2D-image
0.066	-	3beta-7alpha-dihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 1	285606	2D-image
0.071	-	3beta-7alpha-dihydroxy-5beta-cholanoate	Rattus norvegicus	-	isoenzyme 4	285606	2D-image
0.12	-	4-bromobenzyl alcohol	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
0.4	-	4-bromobenzyl alcohol	Sulfolobus solfataricus	-	carboxymethylated enzyme, at 55�C	678116	2D-image
0.12	-	4-bromobenzylalcohol	Sulfolobus solfataricus	-	in the presence of 3 mM NAD+, in 0.1 M glycine-NaOH, pH 9.2, at 65�C	681763	2D-image
0.28	-	4-carboxybenzaldehyde	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
0.28	-	4-carboxybenzaldehyde	Sulfolobus solfataricus	-	in 50 mM Tris-HCl (pH 7.5) containing 0.2 mM NADH + H+, at 65�C	681763	2D-image
0.00048	-	4-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	2D-image
0.001	-	4-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	2D-image
0.0021	-	4-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	2D-image
0.0038	-	4-formylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	2D-image
0.004	-	4-hydroxy-retinol	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B1	654370	2D-image
0.011	-	4-hydroxy-retinol	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B2	654370	2D-image
0.015	-	4-hydroxy-retinol	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH4	654370	2D-image
0.00037	-	4-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH3, at 21-23�C	701322	-
0.001	-	4-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	-
0.0029	-	4-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	-
0.04	-	4-hydroxymethylpyrene	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	-
0.024	-	4-Methoxybenzaldehyde	Sulfolobus solfataricus	-	wild type enzyme, at 65�C	678121	2D-image
0.14	-	4-Methoxybenzaldehyde	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
0.14	-	4-Methoxybenzaldehyde	Sulfolobus solfataricus	-	in 50 mM Tris-HCl (pH 7.5) containing 0.2 mM NADH + H+, at 65�C	681763	2D-image
0.86	-	4-Methoxybenzaldehyde	Sulfolobus solfataricus	-	mutant enzyme N249Y, at 65�C	678121	2D-image
0.07	-	4-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.12	-	4-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.23	-	4-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	wild type enzyme, at 65�C	678121	2D-image
1.24	-	4-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	mutant enzyme N249Y, at 65�C	678121	2D-image
1.3	-	4-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
1.3	-	4-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
1.4	-	4-Methoxybenzyl alcohol	Sulfolobus solfataricus	-	carboxymethylated enzyme, at 55�C	678116	2D-image
61	-	4-Methoxybenzyl alcohol	Thermus thermophilus	-	65�C	684583	2D-image
1.3	-	4-methoxybenzylalcohol	Sulfolobus solfataricus	-	in the presence of 3 mM NAD+, in 0.1 M glycine-NaOH, pH 9.2, at 65�C	681763	2D-image
6.7	-	4-Methyl-1-pentanol	Equus caballus	-	mutant enzyme W54L	285647	2D-image
53.8	-	4-Methyl-1-pentanol	Equus caballus	-	wilde-type enzyme ADh1	285647	2D-image
0.81	-	4-methylpentan-1-ol	Scaptodrosophila lebanonensis	-	-	285616	2D-image
0.017	-	4-oxo-retinal	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH4	654370	2D-image
0.025	-	4-oxo-retinal	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B1	654370	2D-image
0.027	-	4-oxo-retinal	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B2	654370	2D-image
0.0036	-	5alpha-androstan-17beta-ol-3-one	Homo sapiens	-	pH 7.3, 37�C, ADH1C*2 (gamma2gamma2)	655206	2D-image
0.021	-	5alpha-androstan-17beta-ol-3-one	Rattus norvegicus	-	isoenzyme 2	285606	2D-image
0.025	-	5alpha-androstan-17beta-ol-3-one	Rattus norvegicus	-	isoenzyme 2	285606	2D-image
0.027	-	5alpha-androstan-17beta-ol-3-one	Rattus norvegicus	-	isoenzyme 4	285606	2D-image
0.04	-	5alpha-androstan-17beta-ol-3-one	Rattus norvegicus	-	isoenzyme 1	285606	2D-image
0.011	-	5beta-androstan-17beta-ol-3-one	Equus caballus	-	pH 7.3, 37�C, recombinant enzyme	655206	2D-image
0.046	-	5beta-androstan-17beta-ol-3-one	Homo sapiens	-	pH 7.3, 37�C, ADH1C*2 (gamma2gamma2)	655206	2D-image
0.123	-	5beta-androstan-3beta-ol-17 one	Rattus norvegicus	-	isoenzyme 4	285606	2D-image
0.125	-	5beta-androstan-3beta-ol-17 one	Rattus norvegicus	-	isoenzyme 2	285606	2D-image
0.14	-	5beta-androstan-3beta-ol-17 one	Rattus norvegicus	-	isoenzyme 3	285606	2D-image
0.164	-	5beta-androstan-3beta-ol-17 one	Rattus norvegicus	-	isoenzyme 1	285606	2D-image
0.003	-	5beta-Androstan-3beta-ol-17-one	Equus caballus	-	pH 7.3, 37�C, recombinant enzyme	655206	2D-image
0.058	-	5beta-Androstan-3beta-ol-17-one	Homo sapiens	-	pH 7.3, 37�C, ADH1C*2 (gamma2gamma2)	655206	2D-image
0.008	-	5beta-cholanic acid-3-one	Equus caballus	-	pH 7.3, 37�C, recombinant enzyme	655206	2D-image
0.25	-	5beta-cholanic acid-3-one	Homo sapiens	-	pH 7.3, 37�C, ADH1C*2 (gamma2gamma2)	655206	2D-image
0.047	-	5beta-Pregnan-21-ol-3,20-dione hemisuccinate	Equus caballus	-	-	285597	2D-image
0.0036	-	5beta-pregnan-3,20-dione	Homo sapiens	-	pH 7.3, 37�C, ADH1C*2 (gamma2gamma2)	655206	2D-image
0.027	-	5beta-Pregnan-3beta-ol-20-one	Homo sapiens	-	pH 7.3, 37�C, ADH1C*2 (gamma2gamma2)	655206	2D-image
0.16	-	9-cis-retinal	Equus caballus	-	oxidation with NAD+	285648	2D-image
0.242	-	9-cis-retinal	Equus caballus	-	reduction with NADH	285648	2D-image
0.011	-	9-cis-retinol	Homo sapiens	-	isozyme ADH1B1, pH 7.5, 25�C	655479	2D-image
0.023	-	9-cis-retinol	Homo sapiens	-	isozyme ADH1B2, pH 7.5, 25�C	655479	2D-image
0.3	-	9-cis-retinol	Equus caballus	-	oxidation with NAD+	285648	2D-image
0.0086	-	acetaldehyde	Sporotrichum pulverulentum	-	-	285639	2D-image
0.013	-	acetaldehyde	Natronomonas pharaonis	-	70�C, pH 9.0, 50 mM Tris-HCl, 4 M NaCl	686626	2D-image
0.053	-	acetaldehyde	Emericella nidulans	-	-	285636	2D-image
0.059	-	acetaldehyde	Natronomonas pharaonis	-	40�C, pH 9.0, 50 mM Tris-HCl, 4 M NaCl	686626	2D-image
0.085	-	acetaldehyde	Homo sapiens	-	isoenzyme beta1,beta1	285570, 285575	2D-image
0.086	-	acetaldehyde	Zymomonas mobilis	-	enzyme form ADH I	285623	2D-image
0.1	-	acetaldehyde	Saimiri sciureus	-	pyrazole-sensitive enzyme, pH 7.0	285579	2D-image
0.194	-	acetaldehyde	Meyerozyma guilliermondii	-	-	285640	2D-image
0.217	-	acetaldehyde	Rattus norvegicus	-	isoenzyme 3	285606	2D-image
0.23	-	acetaldehyde	Rattus norvegicus	-	isoenzyme 2	285606	2D-image
0.24	-	acetaldehyde	Homo sapiens	-	isoenzyme gamma2,gamma2; isoenzymes beta2,beta2	285570	2D-image
0.24	-	acetaldehyde	Homo sapiens	-	isoenzymes beta2,beta2	285575	2D-image
0.276	-	acetaldehyde	Rattus norvegicus	-	isoenzyme 4	285606	2D-image
0.3	-	acetaldehyde	Acetobacter pasteurianus	-	isozyme ADH I, pH 5.5, 25�C	655058	2D-image
0.31	-	acetaldehyde	Rattus norvegicus	-	isoenzyme 1	285606	2D-image
0.33	-	acetaldehyde	Homo sapiens	-	isoenzyme gamma1,gamma1	285570	2D-image
0.34	-	acetaldehyde	Homo sapiens	P00326, P08319	isozyme ADH1C, at 21-23�C	701322	2D-image
0.6	-	acetaldehyde	Petroselinum crispum	-	-	285627	2D-image
0.92	-	acetaldehyde	Corynebacterium glutamicum R	-	33�C, pH 7	684612	2D-image
1.25	-	acetaldehyde	Chlamydomonas moewusii	-	-	285624	2D-image
1.25	-	acetaldehyde	Hordeum vulgare	-	isoenzyme II	285634	2D-image
1.3	-	acetaldehyde	Zymomonas mobilis	-	enzyme form ADH II	285623	2D-image
1.45	-	acetaldehyde	Hordeum vulgare	-	isoenzyme I	285634	2D-image
1.8	-	acetaldehyde	Desulfovibrio gigas	-	-	285654	2D-image
1.9	-	acetaldehyde	Crocus sativus	-	pH 8.5	654140	2D-image
2.25	-	acetaldehyde	Geobacillus thermodenitrificans	A4IP64, A4ISB9	cosubstrate NADPH, pH 8.0, 60�C	712962	2D-image
2.83	-	acetaldehyde	Saccharomyces cerevisiae	-	-	285642	2D-image
3.4	-	acetaldehyde	Homo sapiens	-	isoenzyme beta3,beta3	285575	2D-image
4.3	-	acetaldehyde	Homo sapiens	-	isoenzyme alpha,alpha	285570	2D-image
4.71	-	acetaldehyde	Geobacillus thermodenitrificans	A4IP64, A4ISB9	cosubstrate NADH, pH 8.0, 60�C	712962	2D-image
6	-	acetaldehyde	Equus caballus	-	-	285583, 285597	2D-image
7.05	-	acetaldehyde	Oryza sativa	-	-	285561	2D-image
11.5	-	acetaldehyde	Saimiri sciureus	-	pyrazole-insensitive enzyme, pH 7.0	285579	2D-image
12.7	-	acetaldehyde	Homo sapiens	P00326, P08319	isozyme ADH4, at 21-23�C	701322	2D-image
24	-	acetaldehyde	Acetobacter pasteurianus	-	isozyme ADH II, pH 6.0, 25�C	655058	2D-image
26	-	acetaldehyde	Homo sapiens	P00326, P08319	isozyme ADH2, at 21-23�C	701322	2D-image
70	-	acetaldehyde	Zea mays	-	mutant enzyme ADH1-1S1108	285652	2D-image
85	-	acetaldehyde	Zea mays	-	wild-type enzyme ADH1-1S	285652	2D-image
6.6	-	acetone	Sulfolobus solfataricus	-	-	285621	2D-image
135	-	acetone	Equus caballus	-	-	285586	2D-image
0.011	-	all-trans-retinal	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B1	654370	2D-image
0.012	-	all-trans-retinal	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B2	654370	2D-image
0.034	-	all-trans-retinal	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH4	654370	2D-image
0.26	-	all-trans-retinal	Equus caballus	-	oxidation with NAD+	285648	2D-image
0.34	-	all-trans-retinal	Equus caballus	-	reduction with NADH	285648	2D-image
0.009	-	all-trans-retinol	Homo sapiens	-	-	285608	2D-image
0.02	-	all-trans-retinol	Mesocricetus auratus	-	isoenzyme TT-ADH	285650	2D-image
0.023	-	all-trans-retinol	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH4	654370	2D-image
0.03	-	all-trans-retinol	Mesocricetus auratus	-	isoenzyme BB-ADH	285650	2D-image
0.03	-	all-trans-retinol	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B1	654370	2D-image
0.03	-	all-trans-retinol	Homo sapiens	-	isozyme ADH1B1, pH 7.5, 25�C	655479	2D-image
0.033	-	all-trans-retinol	Homo sapiens	-	pH 7.5, 25�C, isozyme ADH1B2	654370	2D-image
0.033	-	all-trans-retinol	Homo sapiens	-	isozyme ADH1B2, pH 7.5, 25�C	655479	2D-image
0.05	-	all-trans-retinol	Mesocricetus auratus	-	isoenzyme AA-ADH	285650	2D-image
0.059	-	all-trans-retinol	Equus caballus	-	oxidation with NAD+	285648	2D-image
0.39	-	Allyl alcohol	Equus caballus	-	pH 7.3, 37�C	655233	2D-image
5.3	-	alpha-tetralol	Thermus thermophilus	-	65�C	684583	2D-image
5.8	-	alpha-tetralone	Thermus thermophilus	-	65�C	684583	2D-image
0.0025	-	Anisaldehyde	Sulfolobus solfataricus	-	-	285621	2D-image
0.09	-	Anisaldehyde	Sulfolobus solfataricus	-	-	285625	2D-image
0.03	-	benzaldehyde	Sulfolobus solfataricus	-	wild type enzyme, at 65�C	678121	2D-image
0.03	-	benzaldehyde	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.07	-	benzaldehyde	Sulfolobus solfataricus	-	mutant enzyme W95L, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.148	-	benzaldehyde	Equus caballus	-	-	285597	2D-image
0.2	-	benzaldehyde	Sulfolobus solfataricus	-	carboxymethylated enzyme, at 55�C	678116	2D-image
0.26	-	benzaldehyde	Sulfolobus solfataricus	-	mutant enzyme N249Y, at 65�C	678121	2D-image
0.28	-	benzaldehyde	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.3	-	benzaldehyde	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
0.3	-	benzaldehyde	Sulfolobus solfataricus	-	in 50 mM Tris-HCl (pH 7.5) containing 0.2 mM NADH + H+, at 65�C	681763	2D-image
2	3	benzaldehyde	Saccharomyces carlsbergensis	B6UQD0	in the presence of 0.25 mM NADH, in 83 mM potassium phosphate, 40 mM KCl, and 0.25 mM EDTA buffer, pH 7.3, at 30�C	697267	2D-image
14	-	benzaldehyde	Saccharomyces cerevisiae	-	isozyme ADH2, in the presence of 0.25 mM NADH, in 83 mM potassium phosphate, 40 mM KCl, and 0.25 mM EDTA buffer, pH 7.3, at 30�C	697267	2D-image
33	-	benzaldehyde	Saccharomyces cerevisiae	-	isozyme ADH1, in the presence of 0.25 mM NADH, in 83 mM potassium phosphate, 40 mM KCl, and 0.25 mM EDTA buffer, pH 7.3, at 30�C	697267	2D-image
0.007	-	benzyl alcohol	Homo sapiens	-	-	285569	2D-image
0.012	-	benzyl alcohol	Brevibacterium sp.	-	-	669540	2D-image
0.013	-	benzyl alcohol	Coturnix coturnix	-	enzyme form ADH-2	285615	2D-image
0.013	-	benzyl alcohol	Sulfolobus solfataricus	-	-	285621	2D-image
0.046	-	benzyl alcohol	Equus caballus	-	-	285597	2D-image
0.05	-	benzyl alcohol	Rattus norvegicus	-	isoenzyme ADH-3, pH 10.0	285604	2D-image
0.12	-	benzyl alcohol	Sulfolobus solfataricus	-	mutant enzyme W95L, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.15	-	benzyl alcohol	Homo sapiens	-	-	285651	2D-image
0.26	-	benzyl alcohol	Sulfolobus solfataricus	-	wild type enzyme, at 65�C	678121	2D-image
0.26	-	benzyl alcohol	Sulfolobus solfataricus	-	wild type enzyme, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
0.8	-	benzyl alcohol	Sulfolobus solfataricus	-	native enzyme, at 55�C	678116	2D-image
1.4	-	benzyl alcohol	Rattus norvegicus	-	isoenzyme ADH-1, pH 10.0	285604	2D-image
1.5	-	benzyl alcohol	Sulfolobus solfataricus	-	mutant enzyme N249Y, at 65�C	678121	2D-image
2	-	benzyl alcohol	Sulfolobus solfataricus	-	carboxymethylated enzyme, at 55�C	678116	2D-image
3.8	-	benzyl alcohol	Sulfolobus solfataricus	-	mutant enzyme W95L/N249Y, in 0.1 M glycine-NaOH buffer (pH 10.5), at 65�C	697839	2D-image
7.72	-	benzyl alcohol	Methylobacterium extorquens	-	-	669027	2D-image
19.96	-	benzyl alcohol	Fragaria x ananassa	-	-	669027	2D-image
24	-	benzyl alcohol	Saccharomyces carlsbergensis	B6UQD0	in the presence of 2 mM NAD+, in 83 mM potassium phosphate, 40 mM KCl, and 0.25 mM EDTA buffer, pH 7.3, at 30�C	697267	2D-image
34	-	benzyl alcohol	Saccharomyces cerevisiae	-	isozyme ADH1, in the presence of 2 mM NAD+, in 83 mM potassium phosphate, 40 mM KCl, and 0.25 mM EDTA buffer, pH 7.3, at 30�C	697267	2D-image
49	-	benzyl alcohol	Saccharomyces cerevisiae	-	isozyme ADH2, in the presence of 2 mM NAD+, in 83 mM potassium phosphate, 40 mM KCl, and 0.25 mM EDTA buffer, pH 7.3, at 30�C	697267	2D-image
0.0145	-	benzylalcohol	Sulfolobus sp.	P50381	in 50 mM glycine-NaOH at pH 10.0	680428	2D-image
0.44	-	benzylalcohol	Sulfolobus solfataricus	Q9UXF1	2 mM zinc sulfate in 100 mM glycine-NaOH (pH 10.5) at 65�C	681629	2D-image
0.8	-	benzylalcohol	Sulfolobus solfataricus	-	in the presence of 3 mM NAD+, in 0.1 M glycine-NaOH, pH 9.2, at 65�C	681763	2D-image
240	-	beta-NAD+	Saccharomyces cerevisiae	-	in presence of 0.5 mM SDS	689887	2D-image
243	-	beta-NAD+	Saccharomyces cerevisiae	-	in presence of 0.5 mM SDS	689887	2D-image
350	-	beta-NAD+	Saccharomyces cerevisiae	-	in presence of 1 mM SDS	689887	2D-image
710	-	beta-NAD+	Saccharomyces cerevisiae	-	in presence of 3 mM SDS	689887	2D-image
1230	-	beta-NAD+	Saccharomyces cerevisiae	-	in presence of 50 mM SDS	689887	2D-image
2290	-	beta-NAD+	Saccharomyces cerevisiae	-	in presence of 15 mM SDS	689887	2D-image
0.055	-	butan-1-ol	Sulfolobus solfataricus	-	-	285621	2D-image
1.9	-	butan-1-ol	Scaptodrosophila lebanonensis	-	-	285616	2D-image
2	-	butan-1-ol	Coturnix coturnix	-	enzyme form ADH-3	285615	2D-image
3.01	-	butan-1-ol	Drosophila simulans	-	-	285619	2D-image
3.31	-	butan-1-ol	Drosophila melanogaster	-	-	285619	2D-image
0.35	-	butan-2-ol	Sulfolobus solfataricus	-	-	285621	2D-image
0.41	-	butan-2-ol	Drosophila simulans	-	-	285619	2D-image
0.86	-	butan-2-ol	Drosophila melanogaster	-	-	285619	2D-image
1.6	-	butan-2-ol	Drosophila virilis	-	-	285619	2D-image
93.3	-	butan-2-ol	Equus caballus	-	wilde-type enzyme ADh1	285647	2D-image
14	-	Butan-2-one	Sulfolobus solfataricus	-	-	285621	2D-image
3	-	Butanal	Rattus norvegicus	-	isoenzyme ADH-1, pH 7.5	285604	2D-image
4.24	-	Butanal	Corynebacterium glutamicum R	-	33�C, pH 7	684612	2D-image
0.012	-	butanol	Saimiri sciureus	-	pyrazole-sensitive enzyme, pH 7.5	285579	2D-image
0.02	-	butanol	Saimiri sciureus	-	pyrazole-sinensitive enzyme, pH 10.0	285579	2D-image
0.06	-	butanol	Saimiri sciureus	-	pyrazole-insensitive enzyme, pH 7.5	285579	2D-image
0.09	-	butanol	Saimiri sciureus	-	pyrazole-sensitive enzyme, pH 10.0	285579	2D-image
0.091	-	butanol	Equus caballus	-	-	285597	2D-image
0.24	-	butanol	Homo sapiens

All organisms
Acetobacter pasteurianus
Acetobacter pasteurianus SKU1108
Acinetobacter calcoaceticus
Aeropyrum pernix
Alligator mississippiensis
Anastrepha fraterculus
Anastrepha obliqua
Avena sativa
Brassica napus
Brevibacterium sp.
Brevibacterium sp. KU 1309
Camellia sinensis
Candida parapsilosis
Candida parapsilosis CCTCC M203011
Candida sp.
Candida sp. N-16
Chlamydomonas moewusii
Citrullus lanatus
Corynebacterium glutamicum R
Coturnix coturnix
Cricetulus griseus
Crocus sativus
Ctenopharyngodon idella
Cucumis melo
Cytophaga sp. KUC-1
Desulfovibrio gigas
Devosia riboflavina
Devosia riboflavina KNK10702
Dipodascus capitatus
Drosophila funebris
Drosophila immigrans
Drosophila melanogaster
Drosophila simulans
Drosophila virilis
Emericella nidulans
Ensifer adhaerens S-5
Entamoeba histolytica
Entamoeba histolytica HM1:1MSS
Equus caballus
Escherichia coli
Euglena gracilis
Euglena gracilis Z
Euglena longa
Flavobacterium frigidimaris
Fragaria x ananassa
Gallus gallus
Geobacillus stearothermophilus
Geobacillus stearothermophilus LLD-R
Geobacillus thermodenitrificans
Geobacillus thermoglucosidasius
Geobacillus thermoglucosidasius M10EXG
Glycine max
Hafnia alvei
Homo sapiens
Hordeum vulgare
Klebsiella oxytoca
Klebsiella pneumoniae
Kluyveromyces lactis
Kluyveromyces marxianus
Leifsonia sp.
Leifsonia sp. S749
Macaca mulatta
Malus x domestica
Mesocricetus auratus
Methylobacterium extorquens
Meyerozyma guilliermondii
Meyerozyma guilliermondii B10-05
Mucor circinelloides
Mucor circinelloides YR-1
Mus musculus
Naja naja
Najas marina
Natronomonas pharaonis
Neurospora crassa
Neurospora crassa FGSC2489
Oncorhynchus mykiss
Oryctolagus cuniculus
Oryza sativa
Petroselinum crispum
Picrophilus torridus
Pisum sativum
Pseudomonas aeruginosa
Pseudomonas aeruginosa PaADH
Pseudomonas fluorescens
Pseudomonas putida
Rana perezi
Rattus norvegicus
Rhodococcus erythropolis
Rhodococcus ruber
Rhodococcus ruber DSM44541
Saara hardwickii
Saccharomyces carlsbergensis
Saccharomyces carlsbergensis Y379-50
Saccharomyces cerevisiae
Saimiri sciureus
Scaptodrosophila lebanonensis
Schizosaccharomyces pombe
Sporotrichum pulverulentum
Sulfolobus solfataricus
Sulfolobus solfataricus DSM1617
Sulfolobus solfataricus Gtheta
Sulfolobus sp.
Sulfolobus sp. RC3
Suncus murinus
Thermoanaerobacter brockii
Thermoanaerobacter ethanolicus
Thermoanaerobacter ethanolicus JW200
Thermomicrobium roseum
Thermoplasma acidophilum
Thermus sp.
Thermus sp. ATN1
Thermus thermophilus
Triticum aestivum
Triticum monococcum
Triticum turgidum
Vicia faba
Vitis vinifera
Zea mays
Zygosaccharomyces rouxii
Zymomonas mobilis