format-version: 1.2
date: 21:05:2009 21:34
auto-generated-by: OBO-Edit 2.000-beta49

[Term]
id: BTO:0000000
name: brenda source tissue ontology
namespace: BrendaTissueOBO
def: "A structured controlled vocabulary for the source of an enzyme. It comprises terms of tissues, cell lines, cell types and cell cultures from uni- and multicellular organisms." [curators:mgr]

[Term]
id: BTO:0000001
name: culture condition:-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000216 ! culture condition

[Term]
id: BTO:0000002
name: culture condition:1,4-dichlorobenzene-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000003
name: intestinal cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000648 ! intestine

[Term]
id: BTO:0000004
name: culture condition:2,5-dihydroxybenzoate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000005
name: culture condition:2-aminobenzenesulfonate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000006
name: osteoblastoma cell
namespace: BrendaTissueOBO
def: "A benign tumor cell of bone. " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000372 ! bone cancer cell
relationship: DRV BTO:0001593 ! osteoblast

[Term]
id: BTO:0000007
name: HEK-293 cell
namespace: BrendaTissueOBO
def: "Established from a human primary embryonal kidney transformed by adenovirus type 5." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "293 cell" RELATED []
synonym: "A-293 cell" RELATED []
synonym: "A293 cell" RELATED []
synonym: "HEK cell" RELATED []
synonym: "HEK293 cell" RELATED []
synonym: "human embryonal kidney cell" RELATED []
synonym: "human embryonic kidney cell" RELATED []
is_a: BTO:0000067 ! kidney cell line
is_a: BTO:0002733 ! embryonic kidney cell line

[Term]
id: BTO:0000008
name: culture condition:3-chlorobenzoate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000009
name: culture condition:3-hydroxybenzoate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000010
name: culture condition:3-methylcrotonoyl-CoA-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000011
name: 3T3-L1 cell
namespace: BrendaTissueOBO
def: "L1 is a continuous substrain of 3T3 (Swiss albino) developed through clonal isolation. Cells undergo a pre-adipose to adipose like conversion as they progress from a rapidly dividing to a confluent and contact inhibited state. A high serum content in the medium enhances fat accumulation." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
relationship: DRV BTO:0000944 ! NIH-3T3 cell

[Term]
id: BTO:0000012
name: culture condition:4-(methoxymethyl)phenol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000013
name: culture condition:4-chlorophenol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000014
name: culture condition:4-hydroxybenzoate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000015
name: culture condition:4-methylmuconolactone-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000016
name: A-172 cell
namespace: BrendaTissueOBO
def: "Human brain glioblastoma cell line. Established from a 53 year old man." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "A172 cell" RELATED []
is_a: BTO:0001530 ! glioblastoma cell line

[Term]
id: BTO:0000017
name: A-431 cell
namespace: BrendaTissueOBO
def: "Human epidermoid carcinoma established from the solid tumor of an 85-year-old woman; cells were reported to have large numbers of EGF binding sites; cell line was used as indicator cell line for anti-TGF binding." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "A431 cell" RELATED []
is_a: BTO:0000297 ! carcinoma cell line

[Term]
id: BTO:0000018
name: A-549 cell
namespace: BrendaTissueOBO
def: "Human lung carcinoma established from an explanted lung tumor which was removed from a 58-year-old Caucasian man in 1972; cells were described to induce tumors in athmyic mice and to synthesize lecithin." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "A549 cell" RELATED []
synonym: "NCI-A549 cell" RELATED []
is_a: BTO:0000762 ! lung cancer cell line

[Term]
id: BTO:0000019
name: A7r5 cell
namespace: BrendaTissueOBO
def: "Rat embryonic thoracic aorta smooth muscle cell line. The cells exhibit an increase in activity of the enzymes myokinase and creatine phosphokinase (CPK) as the culture reaches stationary phase. Muscle type CPK is synthesized after cell division has ceased." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000669 ! embryonic cell line
is_a: BTO:0001200 ! aorta thoracica smooth muscle cell line

[Term]
id: BTO:0000020
name: abdomen
namespace: BrendaTissueOBO
def: "1: The part of the body between the thorax and the pelvis; also: the cavity of this part of the trunk containing the chief viscera.\n2: The posterior section of the body behind the thorax in an arthropod." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=abdomen]
synonym: "abdominal cavity" RELATED []
relationship: part_of BTO:0001493 ! trunk

[Term]
id: BTO:0000021
name: head muscle
namespace: BrendaTissueOBO
is_a: BTO:0001103 ! skeletal muscle
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0000022
name: abdominal ganglion
namespace: BrendaTissueOBO
def: "The visceral sac's nerve knot is called visceral ganglion. In contrary to the mostly paired other ganglia this nerve knot is unpaired. The visceral ganglion innerves the pallial organs as well as the inner organs." [:Biology, :Czihak, :Langer, :Ziegler, Snails Nervous System:1992]
synonym: "visceral ganglion" RELATED []
is_a: BTO:0000497 ! ganglion
relationship: part_of BTO:0001448 ! visceral hump

[Term]
id: BTO:0000023
name: pectoral muscle
namespace: BrendaTissueOBO
def: "Any of the muscles which connect the ventral walls of the chest with the bones of the upper arm and shoulder and of which there are two on each side of the human body." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pectoral+muscle]
synonym: "breast muscle" RELATED []
synonym: "pectoralis muscle" RELATED []
is_a: BTO:0000508 ! thorax muscle

[Term]
id: BTO:0000024
name: abomasum
namespace: BrendaTissueOBO
def: "The fourth compartment of the ruminant stomach that follows the omasum and has a true digestive function." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=abomasum]
synonym: "fourth stomach" RELATED []
is_a: BTO:0001307 ! stomach

[Term]
id: BTO:0000025
name: amniotic cavity
namespace: BrendaTissueOBO
def: "The space within the amnion." [Medical Dictionary:http\://www.edoc.co.za/medilink/dict/359.html]
relationship: part_of BTO:0000065 ! amnion

[Term]
id: BTO:0000026
name: culture condition:galactose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000027
name: achene
namespace: BrendaTissueOBO
def: "A small dry indehiscent one-seeded fruit (as of a sunflower) developing from a simple ovary and usually having a thin pericarp attached to the seed at only one point." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000486 ! fruit

[Term]
id: BTO:0000028
name: pancreatic acinar cell
namespace: BrendaTissueOBO
def: "Cells of the pancreas that secrete digestive enzymes, the archetypal secretory cell upon which much of the early work on the sequence of events in the secretory process was done. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "exocrine pancreas cell" RELATED []
synonym: "pancreatic acinus" RELATED []
is_a: BTO:0000433 ! exocrine acinar cell
relationship: part_of BTO:0000434 ! exocrine pancreas

[Term]
id: BTO:0000029
name: adductor longus
namespace: BrendaTissueOBO
def: "Adductor arising from the superior ramus of the pubis and inserted into the middle third of the linea aspera." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "long adductor muscle" RELATED []
synonym: "musculus adductor longus" RELATED []
is_a: BTO:0000030 ! adductor

[Term]
id: BTO:0000030
name: adductor
namespace: BrendaTissueOBO
def: "Any of three powerful triangular muscles that contribute to the adduction of the human thigh." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "adductor muscle" RELATED []
is_a: BTO:0001367 ! thigh muscle
relationship: part_of BTO:0001376 ! thigh

[Term]
id: BTO:0000031
name: fruit peduncle
namespace: BrendaTissueOBO
relationship: part_of BTO:0000486 ! fruit

[Term]
id: BTO:0000032
name: colonic adenocarcinoma cell
namespace: BrendaTissueOBO
def: "A cell of an adenocarcinoma of the colon is a malignant neoplastic epithelial lesion, arising from the colonic mucosa." [Brown Medical School \, Digital Pathology:http\://www.brown.edu/Courses/Digital_Path/GI/colonic_adenocarcinoma.htm]
synonym: "adenocarcinoma cell, colon" RELATED []
synonym: "colon adenocarcinoma cell" RELATED []
is_a: BTO:0000035 ! colorectal adenocarcinoma cell
is_a: BTO:0000586 ! colonic cancer cell

[Term]
id: BTO:0000033
name: SW-403 cell
namespace: BrendaTissueOBO
def: "Human colon adenocarcinoma, established from the adenocarcinoma (grade III) of a 51-year-old Caucasian woman; cells were described to produce carcinoembryonic antigen (CEA) and to be tumorigenic in nude mice." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "SW403 cell" RELATED []
is_a: BTO:0001913 ! colonic adenocarcinoma cell line

[Term]
id: BTO:0000034
name: apical meristem
namespace: BrendaTissueOBO
def: "A group of cells at the tip of the stem and root that give rise by cell division to the primary tissues and are ultimately responsible for the structural organization of the entire primary plant body." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0000231" RELATED []
relationship: part_of BTO:0000247 ! shoot tip
relationship: part_of BTO:0001191 ! root tip
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0000035
name: colorectal adenocarcinoma cell
namespace: BrendaTissueOBO
def: "Adenocarcinoma cell related to the colon and/or rectum." [Medical Dictionary:http\://www.medterms.com/]
synonym: "adenocarcinoma cell, colorectal" RELATED []
is_a: BTO:0000193 ! rectal cancer cell
is_a: BTO:0000586 ! colonic cancer cell
is_a: BTO:0000604 ! adenocarcinoma cell

[Term]
id: BTO:0000036
name: gastric adenocarcinoma cell
namespace: BrendaTissueOBO
def: "A cell of any of a group of common stomach cancers, usually located in the antrum; it may present as a bulky mass with central ulceration invading the wall, a mass that narrows the antral lumen, a polypoid lesion, or a tumor that spreads superficially over the mucosal surface. It is common in Japan, Chile, Iceland, and Finland but the incidence is decreasing in North America and elsewhere. There may be links to certain dietary substances such as nitrosamines and benzpyrene." [Dorlands Medical Dictionary:MerckSource]
synonym: "adenocarcinoma cell of the stomach" RELATED []
synonym: "gastric carcinoma cell" RELATED []
is_a: BTO:0000498 ! gastric cancer cell
is_a: BTO:0000604 ! adenocarcinoma cell

[Term]
id: BTO:0000037
name: renal cell carcinoma cell
namespace: BrendaTissueOBO
def: "Carcinoma cell of the renal parenchyma usually occurring in middle age or later and composed of tubular cells in varying arrangements; symptoms depend on extent of invasion." [Dorlands Medical Dictionary:MerckSource]
synonym: "adenocarcinoma cell of kidney" RELATED []
synonym: "CCRCC cell" RELATED []
synonym: "clear cell carcinoma cell" RELATED []
synonym: "clear cell renal cell carcinoma cell" RELATED []
synonym: "Grawitz`s tumor cell" RELATED []
synonym: "hypernephroid carcinoma cell" RELATED []
synonym: "hypernephroma cell" RELATED []
synonym: "kidney adenocarcinoma cell" RELATED []
synonym: "renal adenocarcinoma cell" RELATED []
is_a: BTO:0000604 ! adenocarcinoma cell
is_a: BTO:0000680 ! kidney cancer cell

[Term]
id: BTO:0000038
name: SW-480 cell
namespace: BrendaTissueOBO
def: "Human colon adenocarcinoma, established from the tumor of a 50-year-old Caucasian man with colon adenocarcinoma." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "SW480 cell" RELATED []
is_a: BTO:0001913 ! colonic adenocarcinoma cell line

[Term]
id: BTO:0000039
name: root cap
namespace: BrendaTissueOBO
def: "A thimble-shaped group of cells found at the tip of roots; it functions to protect the meristem." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005429" RELATED []
relationship: part_of BTO:0001191 ! root tip

[Term]
id: BTO:0000040
name: adenohypophysis
namespace: BrendaTissueOBO
def: "The anterior glandular lobe of the pituitary gland." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=adenohypophysis]
synonym: "anterior pituitary" RELATED []
synonym: "anterior pituitary gland" RELATED []
relationship: part_of BTO:0000496 ! anterior lobe

[Term]
id: BTO:0000041
name: medulla oblongata
namespace: BrendaTissueOBO
def: "The part of the vertebrate brain that is continuous posteriorly with the spinal cord and that contains the centers controlling involuntary vital functions." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=medulla+oblongata]
relationship: part_of BTO:0000758 ! myelencephalon

[Term]
id: BTO:0000042
name: animal
namespace: BrendaTissueOBO
def: "Any of a kingdom (Animalia) of living things including many-celled organisms and often many of the single-celled ones (as protozoans) that typically differ from plants in having cells without cellulose walls, in lacking chlorophyll and the capacity for photosynthesis, in requiring more complex food materials (as proteins), in being organized to a greater degree of complexity, and in having the capacity for spontaneous movement and rapid motor responses to stimulation." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=animal]
synonym: "animalia" RELATED []
synonym: "metazoa" RELATED []
is_a: BTO:0000000 ! brenda source tissue ontology

[Term]
id: BTO:0000043
name: cerebellar cortex
namespace: BrendaTissueOBO
def: "The superficial gray matter of the cerebellum. It consists of three layers, the stratum moleculare, stratum granulosum, and stratum purkinjense." [Dorlands Medical Dictionary:MerckSource]
synonym: "cortex cerebellaris" RELATED []
relationship: part_of BTO:0000232 ! cerebellum

[Term]
id: BTO:0000044
name: tear gland
namespace: BrendaTissueOBO
def: "An acinous gland that is about the size and shape of an almond, secretes tears, and is situated laterally and superiorly to the bulb of the eye in a shallow depression on the inner surface of the frontal bone." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "lacrimal gland" RELATED []
is_a: BTO:0000431 ! excretory gland
relationship: part_of BTO:0000439 ! eye

[Term]
id: BTO:0000045
name: adrenal cortex
namespace: BrendaTissueOBO
def: "The outer portion of the adrenal glands that produces several steroid hormones, including cortisol and aldosterone." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "cortex glandulae suprarenalis" RELATED []
synonym: "suprarenal cortex" RELATED []
relationship: part_of BTO:0000047 ! adrenal gland

[Term]
id: BTO:0000046
name: Y-1 cell
namespace: BrendaTissueOBO
def: "Mouse adrenal cortex tumor. Mouse, LAF1 male; Tissue: adrenal cortex; Tumor: adrenal tumor." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "Y1 cell" RELATED []
is_a: BTO:0000851 ! adrenal cortex cell line

[Term]
id: BTO:0000047
name: adrenal gland
namespace: BrendaTissueOBO
def: "Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=adrenal+gland]
synonym: "adrenal" RELATED []
synonym: "adrenal capsule" RELATED []
synonym: "atrabiliary capsule" RELATED []
synonym: "epinephros" RELATED []
synonym: "glandula suprarenalis" RELATED []
synonym: "suprarenal capsule" RELATED []
synonym: "suprarenal gland" RELATED []
is_a: BTO:0001488 ! endocrine gland
is_a: BTO:0001491 ! viscus

[Term]
id: BTO:0000048
name: zona glomerulosa
namespace: BrendaTissueOBO
def: "The outermost of the three layers of the adrenal cortex that consists of round masses of granular epithelial cells that stain deeply." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "glomerulosa" RELATED []
relationship: part_of BTO:0000045 ! adrenal cortex

[Term]
id: BTO:0000049
name: adrenal medulla
namespace: BrendaTissueOBO
def: "The inner, reddish-brown portion of the adrenal glands that synthesizes, stores, and releases epinephrine and norepinephrine." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000047 ! adrenal gland

[Term]
id: BTO:0000050
name: zona fasciculata
namespace: BrendaTissueOBO
def: "The middle of the three layers of the adrenal cortex that consists of radially arranged columnar epithelial cells. " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0000045 ! adrenal cortex

[Term]
id: BTO:0000051
name: tendon sheath
namespace: BrendaTissueOBO
def: "A synovial sheath covering a tendon (as in the hand or foot) . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0001356 ! tendon

[Term]
id: BTO:0000052
name: stoma
namespace: BrendaTissueOBO
def: "The epidermal complex consisting of two guard cells and the pore between them." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005350" RELATED []
synonym: "stomatal complex" RELATED []
relationship: part_of BTO:0000718 ! leaf epidermis

[Term]
id: BTO:0000053
name: albedo
namespace: BrendaTissueOBO
def: "The spongy white tissue on the inside of the rind of citrus fruit." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000733 ! exocarp

[Term]
id: BTO:0000054
name: albumen gland
namespace: BrendaTissueOBO
def: "The posterior oviduct opens into the large white albumen gland which adds a layer of albumen to the zygote before it reaches the egg capsule gland." [Invertebrate Anatomy OnLine \, Ilyanassa obsoleta:http\://www.lander.edu/rsfox/310ilyanassaLab.html]
is_a: BTO:0000254 ! female reproductive gland
relationship: REL BTO:0000369 ! egg

[Term]
id: BTO:0000055
name: pars recta
namespace: BrendaTissueOBO
def: "Proximal straight tubule: part of the descending limb of the renal tubule, extending from the proximal convoluted tubule to the thin tubule." [Dorlands Medical Dictionary:MerckSource]
synonym: "pars recta tubuli renalis" RELATED []
relationship: part_of BTO:0001498 ! renal proximal tubule

[Term]
id: BTO:0000056
name: zona reticulata
namespace: BrendaTissueOBO
def: "The innermost of the three layers of the adrenal cortex that consists of irregularly arranged cylindrical masses of epithelial cells. " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0000045 ! adrenal cortex

[Term]
id: BTO:0000057
name: aleurone layer
namespace: BrendaTissueOBO
def: "A group of cells rich in protein granules and located as the outer layer of the endosperm of many grain seeds." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "aleurone" RELATED []
synonym: "GRO:0005360" RELATED []
is_a: BTO:0000390 ! endosperm

[Term]
id: BTO:0000058
name: alimentary canal
namespace: BrendaTissueOBO
def: "The mucous membrane-lined tube of the digestive system through which food passes, in which digestion takes place, and from which wastes are eliminated. It extends from the mouth to the anus and includes the pharynx, esophagus, stomach, and intestines." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "digestive canal" RELATED []
synonym: "digestive tract" RELATED []
synonym: "digestive tube" RELATED []
is_a: BTO:0001491 ! viscus

[Term]
id: BTO:0000059
name: renal epithelium
namespace: BrendaTissueOBO
synonym: "kidney epithelium" RELATED []
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0000671 ! kidney

[Term]
id: BTO:0000060
name: alveolus
namespace: BrendaTissueOBO
def: "A tiny, thin-walled, capillary-rich sac in the lungs where the exchange of oxygen and carbon dioxide takes place." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "air sac" RELATED []
synonym: "alveoli" RELATED []
relationship: part_of BTO:0000061 ! alveolar sac

[Term]
id: BTO:0000061
name: alveolar sac
namespace: BrendaTissueOBO
def: "Each large alveolar sac is like a grape cluster which contains ten or more alveoli." [The Probert Encyclopaedia \, Medicine:http\://www.probertencyclopaedia.com/E1B.HTM]
relationship: part_of BTO:0000136 ! bronchoalveolar system

[Term]
id: BTO:0000062
name: amastigote
namespace: BrendaTissueOBO
def: "Any of the bodies representing the morphologic (leishmanial) stage in the life cycle of all trypanosomatid protozoa resembling the typical adult form of members of the genus Leishmania, in which the oval or round cell has a nucleus, kinetoplast, and basal body but lacks a free-flowing flagellum, the flagellum being either very short or entirely absent." [Dorlands Medical Dictionary:MerckSource]
synonym: "aflagellate form" RELATED []
synonym: "Leishman-Donovan body" RELATED []
synonym: "leishmanial form" RELATED []
synonym: "micromastigote" RELATED []
synonym: "spheromastigote" RELATED []
is_a: BTO:0000092 ! trypanosome

[Term]
id: BTO:0000063
name: culture condition:ammonium malate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000064
name: amniochorion
namespace: BrendaTissueOBO
def: "Pertaining to the amnion and chorion." [Dorlands Medical Dictionary:MerckMedicus]
synonym: "Chorioamnion" RELATED []
is_a: BTO:0000473 ! fetal membrane

[Term]
id: BTO:0000065
name: amnion
namespace: BrendaTissueOBO
def: "A thin, tough, membranous sac that encloses the embryo or fetus of a mammal, bird, or reptile. It is filled with a serous fluid in which the embryo is suspended." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000473 ! fetal membrane

[Term]
id: BTO:0000066
name: amniocyte
namespace: BrendaTissueOBO
def: "A cell of fetal origin obtained in an amniotic fluid specimen." [Dorlands Medical Dictionary:MerckMedicus]
synonym: "amniotic cell" RELATED []
relationship: part_of BTO:0000065 ! amnion

[Term]
id: BTO:0000067
name: kidney cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000671 ! kidney

[Term]
id: BTO:0000068
name: amniotic fluid
namespace: BrendaTissueOBO
def: "Fluid within the amniotic cavity produced by the amnion during the early embryonic period, and later by the lungs and kidneys; at first crystal clear, it later becomes cloudy. It protects the embryo and fetus from injury. The amount at term normally varies from 500 to 1500 mL." [Dorlands Medical Dictionary:MerckSource]
synonym: "acqua amnii" RELATED []
synonym: "liquor amnii" RELATED []
relationship: REL BTO:0000025 ! amniotic cavity

[Term]
id: BTO:0000069
name: WISH cell
namespace: BrendaTissueOBO
def: "Human amnion cell line with HeLa markers." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000110 ! amniotic cell line

[Term]
id: BTO:0000070
name: amoeba
namespace: BrendaTissueOBO
def: "Any of a large genus (Amoeba) of naked rhizopod protozoans with lobed and never anastomosing pseudopodia, without permanent organelles or supporting structures, and of wide distribution in fresh and salt water and moist terrestrial environments." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=amoeba]
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0000071
name: amoebocyte
namespace: BrendaTissueOBO
def: "A cell (as a phagocyte) having amoeboid form or movements." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=amoebocyte]
is_a: BTO:0001044 ! phagocyte
is_a: BTO:0002856 ! coelomocyte

[Term]
id: BTO:0000072
name: carpel
namespace: BrendaTissueOBO
def: "The female reproductive part of a flower, consisting of stigma, style, and ovary." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005441" RELATED []
synonym: "pistil" RELATED []
relationship: part_of BTO:0001733 ! gynoecium

[Term]
id: BTO:0000073
name: culture condition:aniline-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000074
name: antenna
namespace: BrendaTissueOBO
def: "One of a pair of slender movable segmented sensory organs on the head of insects, myriapods, and crustaceans." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=antenna]
is_a: BTO:0000202 ! sense organ
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0000075
name: antennal gland
namespace: BrendaTissueOBO
def: "Excretory gland situated in the basal article of the antennal peduncle." [Crustacea Glossary:http\://atiniui.nhm.org/glossary/index.html?terms=Antennal+gland]
is_a: BTO:0000431 ! excretory gland
relationship: part_of BTO:0000074 ! antenna

[Term]
id: BTO:0000076
name: anterior midgut
namespace: BrendaTissueOBO
relationship: part_of BTO:0000863 ! midgut

[Term]
id: BTO:0000077
name: posterior midgut
namespace: BrendaTissueOBO
relationship: part_of BTO:0000863 ! midgut

[Term]
id: BTO:0000078
name: microglia
namespace: BrendaTissueOBO
alt_id: BTO:0000103
def: "MERGED DEFINITION:\nTARGET DEFINITION: The small, non-neural, interstitial cells of mesodermal origin that form part of the supporting structure of the central nervous system. They are of various forms and may have slender branched processes. They are migratory and act as phagocytes to waste products of nerve tissue. \n--------------------\nSOURCE DEFINITION: One of the small interstitial phagocytic cells of the microglia." [Dorlands Medical Dictionary:MerckSource]
synonym: "Hortega cell" RELATED []
synonym: "microglial cell" EXACT []
synonym: "microgliocyte" RELATED []
is_a: BTO:0000524 ! glia
is_a: BTO:0000801 ! macrophage

[Term]
id: BTO:0000079
name: anther
namespace: BrendaTissueOBO
def: "The male reproductive organ enclosing and containing the pollen grains. " [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005596" RELATED []
relationship: part_of BTO:0001559 ! stamen

[Term]
id: BTO:0000080
name: male reproductive gland
namespace: BrendaTissueOBO
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0000082 ! male reproductive system

[Term]
id: BTO:0000081
name: reproductive system
namespace: BrendaTissueOBO
def: "Reproductive: of, relating to, or capable of reproduction." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=reproductive]
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000082
name: male reproductive system
namespace: BrendaTissueOBO
def: "The reproductive system in men includes the prostate, the testes, and the penis. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
is_a: BTO:0000081 ! reproductive system

[Term]
id: BTO:0000083
name: female reproductive system
namespace: BrendaTissueOBO
def: "The reproductive system in women includes the ovaries, the fallopian tubes, the uterus (womb), the cervix, and the vagina (birth canal)." [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "gynaecological tissue" RELATED []
is_a: BTO:0000081 ! reproductive system

[Term]
id: BTO:0000084
name: vermiform appendix
namespace: BrendaTissueOBO
def: "A narrow blind tube usually about three or four inches (7.6 to 10.2 centimeters) long that extends from the cecum in the lower right-hand part of the abdomen, has much lymphoid wall tissue, normally communicates with the cavity of the cecum, and represents an atrophied terminal part of the cecum. " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0000166 ! cecum

[Term]
id: BTO:0000085
name: appressorium
namespace: BrendaTissueOBO
def: "The flattened thickened tip of a hyphal branch by which some parasitic fungi are attached to their host." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=appressorium]
relationship: part_of BTO:0000612 ! hypha

[Term]
id: BTO:0000086
name: culture condition:arabinose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000087
name: arterial smooth muscle
namespace: BrendaTissueOBO
synonym: "arterial smooth muscle cell" RELATED []
is_a: BTO:0001260 ! smooth muscle
relationship: part_of BTO:0000573 ! artery

[Term]
id: BTO:0000088
name: cardiovascular system
namespace: BrendaTissueOBO
def: "The system of heart and blood vessels." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cardiovascular]
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000089
name: blood
namespace: BrendaTissueOBO
def: "1: The fluid that circulates in the heart, arteries, capillaries, and veins of a vertebrate animal carrying nourishment and oxygen to and bringing away waste products from all parts of the body.\n2: A comparable fluid of an invertebrate." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=blood]
relationship: part_of BTO:0000570 ! hematopoietic system

[Term]
id: BTO:0000090
name: ascidian
namespace: BrendaTissueOBO
def: "Any of a class (Ascidiacea) of solitary or colonial sessile tunicates that have an oral and an atrial siphon." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ascidian]
synonym: "sea squirt" RELATED []
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0000091
name: ascites
namespace: BrendaTissueOBO
def: "Accumulation of serous fluid in the spaces between tissues and organs in the cavity of the abdomen." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ascites]
synonym: "ascites fluid" RELATED []
relationship: part_of BTO:0000020 ! abdomen

[Term]
id: BTO:0000092
name: trypanosome
namespace: BrendaTissueOBO
def: "Any of a genus (Trypanosoma) of parasitic flagellate protozoans that infest the blood of various vertebrates including humans, are usually transmitted by the bite of an insect, and include some that cause serious disease (as sleeping sickness)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=trypanosome]
is_a: BTO:0000464 ! flagellate

[Term]
id: BTO:0000093
name: MCF-7 cell
namespace: BrendaTissueOBO
def: "Human breast adenocarcinoma, established from the pleural effusion of a 69-year-old caucasian woman with metastatic mammary carcinoma (after radio- and hormone therapy) in 1970; cells were described of being positive for cytoplasmic estrogen receptors and  having the capability to form domes." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "MCF7 cell" RELATED []
is_a: BTO:0001912 ! breast adenocarcinoma cell line

[Term]
id: BTO:0000094
name: ascites tumor cell
namespace: BrendaTissueOBO
relationship: DRV BTO:0000091 ! ascites

[Term]
id: BTO:0000095
name: F9 cell
namespace: BrendaTissueOBO
def: "Mouse embryonal carcinoma, initiated from a testicular teratocarcinoma of a strain 129 mouse." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "F9 EC cell" RELATED []
synonym: "F9 embryonal carcinoma cell" RELATED []
synonym: "F9-EC cell" RELATED []
is_a: BTO:0000306 ! teratocarcinoma cell line
is_a: BTO:0001437 ! embryonic carcinoma cell line

[Term]
id: BTO:0000096
name: urinary bladder cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001418 ! urinary bladder

[Term]
id: BTO:0000097
name: ascospore
namespace: BrendaTissueOBO
def: "Any of the spores contained in an ascus." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ascospore]
synonym: "FAO:0000016" RELATED []
is_a: BTO:0001171 ! spore
relationship: part_of BTO:0002161 ! ascocarp

[Term]
id: BTO:0000098
name: astroblast
namespace: BrendaTissueOBO
def: "An embryonic astrocyte." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000930 ! neuroblast

[Term]
id: BTO:0000099
name: astrocyte
namespace: BrendaTissueOBO
def: "A star-shaped cell, especially a neuroglial cell of nervous tissue." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000771 ! macroglia
relationship: DRV BTO:0000098 ! astroblast
relationship: part_of BTO:0003852 ! astroglia

[Term]
id: BTO:0000100
name: astrocytoma cell
namespace: BrendaTissueOBO
def: "A tumor cell composed of astrocytes; it is the most common type of primary brain tumor and is also found throughout the central nervous system. One classification groups astrocytomas according to their histologic appearance and distinguishes pilocytic, protoplasmic, gemistocytic, and fibrillary types. Another classification groups them in order of increasing malignancy as Grade I, Grade II, Grade III, and Grade IV types." [Dorlands Medical Dictionary:MerckSource]
synonym: "astrocytic glioma cell" RELATED []
is_a: BTO:0000526 ! glioma cell
relationship: DRV BTO:0000099 ! astrocyte

[Term]
id: BTO:0000101
name: astrocytoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000690 ! brain cancer cell line
relationship: DRV BTO:0000100 ! astrocytoma cell
relationship: DRV BTO:0001531 ! glial cell line

[Term]
id: BTO:0000102
name: blood clot
namespace: BrendaTissueOBO
def: "A semisolid gelatinous mass of coagulated blood that consists of red blood cells, white blood cells, and platelets entrapped in a fibrin network." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "thrombus" RELATED []
relationship: DRV BTO:0000089 ! blood

[Term]
id: BTO:0000104
name: lymphoma cell line
namespace: BrendaTissueOBO
def: "Lymphoma means any neoplastic disorder of the lymphoid tissue." [Dorlands Medical Dictionary:MerckSource]
synonym: "lymphadenoma cell line" RELATED []
relationship: DRV BTO:0000785 ! lymphoma cell
relationship: DRV BTO:0001586 ! lymphoid cell line

[Term]
id: BTO:0000105
name: upper epidermis
namespace: BrendaTissueOBO
def: "The epidermal layer directed towards the axis." [Gramene DB:http\://dev.gramene.org/db/ontology/search/]
synonym: "adaxial epidermis" RELATED []
synonym: "GRO:0005683" RELATED []
is_a: BTO:0000718 ! leaf epidermis

[Term]
id: BTO:0000106
name: cranial ganglion
namespace: BrendaTissueOBO
is_a: BTO:0000497 ! ganglion

[Term]
id: BTO:0000107
name: B95-8 cell
namespace: BrendaTissueOBO
def: "Marmoset monkey lymphocytes, established from peripheral blood lymphocytes of a marmoset monkey (saguinus oedipus); cells were described to release high titers of Epstein-Barr virus (EBV) providing a source for transformation of B cells and establishment of continuous cell lines; this cell line has been assigned by the ZKBS (German Central Commission for Biological Safety) to risk group 2." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0001522 ! B-lymphocyte cell line

[Term]
id: BTO:0000108
name: olfactory epithelium
namespace: BrendaTissueOBO
def: "Pseudostratified epithelium lining the olfactory region of the nasal cavity, and containing the receptors for the sense of smell." [Dorlands Medical Dictionary:MerckSource]
synonym: "nasal cavity olfactory epithelium" RELATED []
synonym: "nasal epithelium" RELATED []
synonym: "olfactory mucosa" RELATED []
is_a: BTO:0000912 ! nasal mucosa

[Term]
id: BTO:0000109
name: bacteroid
namespace: BrendaTissueOBO
def: "An irregularly shaped bacterium (as a rhizobium) found especially in root nodules of legumes." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=bacteroid]
is_a: BTO:0000284 ! organism form
relationship: REL BTO:0001190 ! root nodule

[Term]
id: BTO:0000110
name: amniotic cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000065 ! amnion

[Term]
id: BTO:0000111
name: BALB/3T12-3 cell
namespace: BrendaTissueOBO
def: "Derived from a 14-17 day old BALB/c mouse embryo. The cells are tumorigenic, are insensitive to contact inhibition and are susceptible to transformation with SV40 virus." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "3T12 cell" RELATED []
is_a: BTO:0001958 ! embryonic fibroblast cell line

[Term]
id: BTO:0000112
name: sieve cell
namespace: BrendaTissueOBO
def: "The phloem conducting cell in nonangiosperms; they are long and tapered with small sieve areas over much of their surfaces. " [Botany - An Introduction to Plant Biology \, Third Edition:http\://biology.jbpub.com/Botany/interactive_glossary_showterm.cfm?term=sieve]
relationship: part_of BTO:0001058 ! phloem

[Term]
id: BTO:0000113
name: cervical ganglion
namespace: BrendaTissueOBO
def: "Any of three sympathetic ganglia on each side of the neck.  " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0001333 ! sympathetic ganglion

[Term]
id: BTO:0000114
name: basidiocarp
namespace: BrendaTissueOBO
def: "The large fruiting body characteristic of the majority of fungi of the subphylum Basidiomycotina; it is composed of masses of intertwined hyphal elements and produces basidia. Mushrooms and toadstools are common examples." [Dorlands Medical Dictionary:MerckSource]
synonym: "FAO:0000012" RELATED []
is_a: BTO:0000487 ! fruitbody

[Term]
id: BTO:0000115
name: BC3H1 cell
namespace: BrendaTissueOBO
def: "Mouse brain tumor cell line. Established from a mouse tumor induced by nitrosoethylurea with properties characteristic of muscle; cells were described to synthesize adenylate and creatine phosphokinases." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000690 ! brain cancer cell line

[Term]
id: BTO:0000116
name: plant epidermis
namespace: BrendaTissueOBO
def: "A thin surface layer of tissue in higher plants formed by growth of a primary meristem." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=epidermis]
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0000117
name: culture condition:benzoate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000118
name: culture condition:benzoylformate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000119
name: berry
namespace: BrendaTissueOBO
def: "A simple fruit (as a currant, grape, tomato, or banana) with a pulpy or fleshy pericarp." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=berry]
is_a: BTO:0000486 ! fruit

[Term]
id: BTO:0000120
name: BHK-21 cell
namespace: BrendaTissueOBO
def: "Syrian hamster kidney BHK-21 is a subclone (clone 13) of the parental line established from the kidneys of five unsexed, one-day-old hamsters in 1961; cells can be used for virus replication studies." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "baby hamster kidney cell" RELATED []
synonym: "BHK 21 cell" RELATED []
synonym: "BHK-21/C13 cell" RELATED []
is_a: BTO:0001131 ! BHK cell

[Term]
id: BTO:0000121
name: bile
namespace: BrendaTissueOBO
def: "A fluid secreted by the liver and poured into the small intestine via the bile ducts. Important constituents are conjugated bile salts, cholesterol, phospholipid, bilirubin diglucuronide, and electrolytes. Bile is alkaline due to its bicarbonate content, is golden brown to greenish yellow in color, and has a bitter taste. Bile secreted by the liver is concentrated in the gallbladder." [Dorlands Medical Dictionary:MerckSource]
synonym: "fel" RELATED []
synonym: "gall" RELATED []
is_a: BTO:0000346 ! digestive juice
relationship: DRV BTO:0000759 ! liver
relationship: REL BTO:0000493 ! gall bladder

[Term]
id: BTO:0000122
name: bile duct
namespace: BrendaTissueOBO
def: "Any of the ducts that convey bile in and from the liver." [Dorlands Medical Dictionary:MerckSource]
synonym: "biliary duct" RELATED []
synonym: "gall duct" RELATED []
relationship: part_of BTO:0000759 ! liver

[Term]
id: BTO:0000123
name: bladder
namespace: BrendaTissueOBO
def: "A membranous sac in animals that serves as the receptacle of a liquid or contains gas." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=bladder]
is_a: BTO:0001491 ! viscus

[Term]
id: BTO:0000124
name: microspore
namespace: BrendaTissueOBO
def: "Haploid cells produced by meiosis in the anthers of angiosperms; four microspores are produced from a single microsporocyte." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
relationship: DRV BTO:0000540 ! pollen mother cell

[Term]
id: BTO:0000125
name: blast cell
namespace: BrendaTissueOBO
def: "In the monophyletic theory, the least differentiated, totipotential blood cell without commitment as to its particular series, from which all blood cells are derived, preceding a stem cell. " [Dorlands Medical Dictionary:MerckSource]
synonym: "blast" RELATED []
synonym: "hematoblast" RELATED []
synonym: "hematocytoblast" RELATED []
synonym: "hemocytoblast" RELATED []
relationship: part_of BTO:0000089 ! blood

[Term]
id: BTO:0000126
name: blastoderm
namespace: BrendaTissueOBO
def: "The mass of cells produced by cleavage of a fertilized ovum, forming the hollow sphere of the blastula, or the cellular cap above a floor of segmented yolk in the discoblastula of telolecithal eggs. " [Dorlands Medical Dictionary:MerckSource]
synonym: "germinal membrane" RELATED []
synonym: "membrana germinativa" RELATED []
relationship: part_of BTO:0000128 ! blastula
relationship: part_of BTO:0000535 ! germ cell

[Term]
id: BTO:0000127
name: blastospore
namespace: BrendaTissueOBO
def: "A fungal spore produced by budding." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=blastospore]
is_a: BTO:0001171 ! spore

[Term]
id: BTO:0000128
name: blastula
namespace: BrendaTissueOBO
def: "The usually spherical structure produced by cleavage of a zygote, consisting of a single layer of cells (blastoderm) surrounding a fluid-filled cavity (blastocoele)." [Dorlands Medical Dictionary:MerckSource]
synonym: "blastosphere" RELATED []
relationship: DRV BTO:0001508 ! morula

[Term]
id: BTO:0000129
name: basophil
namespace: BrendaTissueOBO
def: "Mammalian granulocyte with large heterochromatic basophilic granules that contain histamine bound to a protein and heparin-like mucopolysaccharide matrix. They are not phagocytic. Very similar to mast cells though it is not clear whether they have common lineage." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "basophil granulocyte" RELATED []
is_a: BTO:0000539 ! granulocyte

[Term]
id: BTO:0000130
name: neutrophil
namespace: BrendaTissueOBO
def: "A granulocyte that is the chief phagocytic white blood cell of the blood." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=neutrophil]
synonym: "neutrophil granulocyte" RELATED []
is_a: BTO:0000539 ! granulocyte
is_a: BTO:0001044 ! phagocyte

[Term]
id: BTO:0000131
name: blood plasma
namespace: BrendaTissueOBO
def: "The fluid portion of the blood in which the particulate components are suspended." [Dorlands Medical Dictionary:MerckSource]
synonym: "plasma" RELATED []
relationship: part_of BTO:0000089 ! blood

[Term]
id: BTO:0000132
name: blood platelet
namespace: BrendaTissueOBO
def: "A minute, nonnucleated, disklike cytoplasmic body found in the blood plasma of mammals that is derived from a megakaryocyte and functions to promote blood clotting" [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "platelet" RELATED []
synonym: "thrombocyte" RELATED []
relationship: DRV BTO:0000843 ! megakaryocyte
relationship: part_of BTO:0000131 ! blood plasma

[Term]
id: BTO:0000133
name: blood serum
namespace: BrendaTissueOBO
def: "The cell-free portion of the blood from which the fibrinogen has been separated in the process of clotting." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0001239 ! serum
relationship: part_of BTO:0000131 ! blood plasma

[Term]
id: BTO:0000134
name: bloodstream form
namespace: BrendaTissueOBO
def: "When living in the mammalian bloodstream T. brucei has neither a functional Krebs cycle nor oxidative phosphorylation nor does it store any carbohydrates. In the bloodstream form. Its metabolism is restricted to the glycolytic pathway alone. " [PMID:9013556]
is_a: BTO:0000092 ! trypanosome

[Term]
id: BTO:0000135
name: aorta
namespace: BrendaTissueOBO
def: "The great arterial trunk that carries blood from the heart to be distributed by branch arteries through the body." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=aorta]
relationship: part_of BTO:0000562 ! heart

[Term]
id: BTO:0000136
name: bronchoalveolar system
namespace: BrendaTissueOBO
def: "System pertaining to a bronchus and alveoli." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000763 ! lung

[Term]
id: BTO:0000137
name: pulmonary artery endothelium
namespace: BrendaTissueOBO
is_a: BTO:0000393 ! endothelium
relationship: part_of BTO:0000778 ! pulmonary artery

[Term]
id: BTO:0000138
name: midbrain
namespace: BrendaTissueOBO
def: "The middle of the three primary divisions of the developing vertebrate brain or the corresponding part of the adult brain." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=midbrain]
synonym: "mesencephalon" RELATED []
relationship: part_of BTO:0000146 ! brain stem

[Term]
id: BTO:0000139
name: body wall
namespace: BrendaTissueOBO
def: "The portion of an animal body that consists of ectoderm and mesoderm, forms the external body surface, and encloses the body cavity." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000140
name: bone
namespace: BrendaTissueOBO
def: "The hard form of connective tissue that constitutes the majority of the skeleton of most vertebrates; it consists of an organic component (the cells and matrix) and an inorganic, or mineral, component; the matrix contains a framework of collagenous fibers and is impregnated with the mineral component, chiefly calcium phosphate (85 per cent) and calcium carbonate (10 per cent), which imparts the quality of rigidity to bone. " [Dorlands Medical Dictionary:MerckSource]
synonym: "osseous tissue" RELATED []
is_a: BTO:0000421 ! connective tissue
relationship: part_of BTO:0001486 ! skeletal system

[Term]
id: BTO:0000141
name: bone marrow
namespace: BrendaTissueOBO
def: "The soft, fatty, vascular tissue that fills most bone cavities and is the source of red blood cells and many white blood cells." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "bone marrow cell" RELATED []
synonym: "medulla ossium" RELATED []
relationship: part_of BTO:0001486 ! skeletal system

[Term]
id: BTO:0000142
name: brain
namespace: BrendaTissueOBO
def: "1: The portion of the vertebrate central nervous system that constitutes the organ of thought and neural coordination, includes all the higher nervous centers receiving stimuli from the sense organs and interpreting and correlating them to formulate the motor impulses, is made up of neurons and supporting and nutritive structures, is enclosed within the skull, and is continuous with the spinal cord through the foramen magnum.\n2: A nervous center in invertebrates comparable in position and function to the vertebrate brain." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=brain]
relationship: part_of BTO:0000227 ! central nervous system
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0000143
name: substantia nigra
namespace: BrendaTissueOBO
def: "The substantia nigra is located in the mesencephalon (mid brain) region of the brain. It is part of the basal ganglia." [Anatomy of the Brain:http\://biology.about.com/library/organs/brain/blsubstantianigra.htm]
relationship: part_of BTO:0000138 ! midbrain
relationship: part_of BTO:0000235 ! basal ganglion

[Term]
id: BTO:0000144
name: meninx
namespace: BrendaTissueOBO
def: "Any of the three membranes that envelop the brain and spinal cord." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=meninx]
synonym: "meninges" RELATED []
relationship: part_of BTO:0000142 ! brain
relationship: part_of BTO:0000282 ! head
relationship: part_of BTO:0001279 ! spinal cord

[Term]
id: BTO:0000145
name: brain myelin
namespace: BrendaTissueOBO
relationship: part_of BTO:0000236 ! cerebral white matter

[Term]
id: BTO:0000146
name: brain stem
namespace: BrendaTissueOBO
def: "The part of the brain composed of the mesencephalon, pons, and medulla oblongata and connecting the spinal cord with the forebrain and cerebrum." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=brain+stem]
synonym: "brainstem" RELATED []
synonym: "truncus encephalicus" RELATED []
relationship: part_of BTO:0000142 ! brain

[Term]
id: BTO:0000147
name: microgametophyte
namespace: BrendaTissueOBO
def: "A plant body or cell lineage, formed by vegetative growth of the microspore, that produces the male gametes of a heterosporous plant. " [Jim Croft`s Flora of Australia:http\://www.cartage.org.lb/en/themes/Reference/dictionary/Biologie/M/182.html]
synonym: "GRO:0000162" RELATED []
synonym: "male gametophyte" RELATED []
is_a: BTO:0000495 ! gametophyte

[Term]
id: BTO:0000148
name: branch
namespace: BrendaTissueOBO
def: "A natural subdivision of a plant stem; especially: a secondary shoot or stem (as a bough) arising from a main axis (as of a tree)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=branch]
synonym: "axillary shoot" RELATED []
synonym: "GRO:0005304" RELATED []
synonym: "lateral shoot" RELATED []
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0000149
name: breast
namespace: BrendaTissueOBO
def: "1: The fore or ventral part of the body between the neck and the abdomen.\n2: Either of the pair of mammary glands extending from the front of the chest in pubescent and adult human females and some other mammals." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=breast]
is_a: BTO:0000254 ! female reproductive gland
is_a: BTO:0000431 ! excretory gland
relationship: part_of BTO:0001368 ! thorax

[Term]
id: BTO:0000150
name: breast cancer cell
namespace: BrendaTissueOBO
alt_id: BTO:0001005
def: "Breast cancer is an uncontrolled growth of malignant breast tissue. Most breast cancers begin in the milk ducts: these are called intraductal cancers. A few, like lobular cancer, start in the milk sacs or lobes." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "breast adenocarcinoma cell" RELATED []
synonym: "breast carcinoma cell" RELATED []
synonym: "mammary carcinoma cell" RELATED []
synonym: "mammary tumor cell" RELATED []
is_a: BTO:0000604 ! adenocarcinoma cell
relationship: DRV BTO:0000149 ! breast

[Term]
id: BTO:0000151
name: extensor
namespace: BrendaTissueOBO
def: "A muscle that, upon contraction, tends to straighten a limb. The antagonist of a flexor muscle." [Illustrated Encyclopedia of Human Anatomic Variation:Part I Muscular System http\://www.vh.org/adult/provider/anatomy/AnatomicVariants/MuscularSystem/Terminology.html]
is_a: BTO:0001103 ! skeletal muscle

[Term]
id: BTO:0000152
name: infected cell
namespace: BrendaTissueOBO
is_a: BTO:0000214 ! cell culture

[Term]
id: BTO:0000153
name: Walker carcinoma 256 cell
namespace: BrendaTissueOBO
def: "A cell of a transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "Walker carcinosarcoma 256 cell" RELATED []
is_a: BTO:0000150 ! breast cancer cell
is_a: BTO:0001207 ! sarcoma cell

[Term]
id: BTO:0000154
name: BRL-3A cell
namespace: BrendaTissueOBO
def: "Rat liver cell line. Established from the buffalo strain of rattus norvegicus." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "BRL3A cell" RELATED []
relationship: DRV BTO:0001933 ! BRL cell

[Term]
id: BTO:0000155
name: bronchoalveolar lavage
namespace: BrendaTissueOBO
def: "A technique by which cells and fluid from bronchioles and lung alveoli are removed for diagnosis of disease or evaluation of treatment. A bronchoscope is wedged into a bronchus and sterile saline is pumped in and then removed along with the fluid and cells to be analyzed." [Dorlands Medical Dictionary:MerckSource]
synonym: "BAL cell" RELATED []
synonym: "bronchoalveolar lavage fluid" RELATED []
relationship: REL BTO:0000136 ! bronchoalveolar system

[Term]
id: BTO:0000156
name: brown adipose tissue
namespace: BrendaTissueOBO
def: "A mammalian heat-producing tissue occurring especially in human newborns and in hibernators." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=brown+fat]
synonym: "brown fat" RELATED []
is_a: BTO:0001487 ! adipose tissue

[Term]
id: BTO:0000157
name: aorta thoracica
namespace: BrendaTissueOBO
def: "Thoracic part of aorta: the proximal portion of the descending aorta, which proceeds from the arch of the aorta and gives rise to the bronchial, esophageal, pericardiac, and mediastinal branches, and the superior phrenic, posterior intercostal III to XI, and subcostal arteries; it is continuous through the diaphragm with the abdominal aorta. " [Dorlands Medical Dictionary:MerckSource]
synonym: "aorta thoracalis" RELATED []
synonym: "pars thoracica aortae" RELATED []
synonym: "thoracic aorta" RELATED []
is_a: BTO:0000135 ! aorta

[Term]
id: BTO:0000158
name: plant bud
namespace: BrendaTissueOBO
def: "A small lateral or terminal protuberance on the stem of a plant that may develop into a flower, leaf, or shoot." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=bud]
synonym: "bud" RELATED []
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0000159
name: bulb
namespace: BrendaTissueOBO
def: "A resting stage of a plant (as the lily, onion, hyacinth, or tulip) that is usually formed underground and consists of a short stem base bearing one or more buds enclosed in overlapping membranous or fleshy leaves." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=bulb]
is_a: BTO:0000720 ! plant form

[Term]
id: BTO:0000160
name: bundle sheath
namespace: BrendaTissueOBO
def: "Sheath of parenchyma or sclerenchyma cells surrounding the vascular bundles in leaves." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005726" RELATED []
relationship: part_of BTO:0000713 ! leaf

[Term]
id: BTO:0000161
name: lung fibroblast cell line
namespace: BrendaTissueOBO
is_a: BTO:0000353 ! lung cell line
is_a: BTO:0000453 ! fibroblast cell line
relationship: DRV BTO:0000764 ! lung fibroblast

[Term]
id: BTO:0000162
name: culture condition:butyrate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000163
name: corolla
namespace: BrendaTissueOBO
def: "Collective term for the petals of a flower." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005654" RELATED []
relationship: part_of BTO:0001727 ! perianth

[Term]
id: BTO:0000164
name: Burkitt lymphoma cell
namespace: BrendaTissueOBO
def: "Malignant tumour cell of lymphoblasts derived from B-lymphocytes. Most commonly affects children in tropical Africa: both Epstein-Barr virus and immunosuppression due to malarial infection are involved." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "African lymphoma cell" RELATED []
synonym: "Burkitt's lymphoma cell" RELATED []
is_a: BTO:0000785 ! lymphoma cell

[Term]
id: BTO:0000165
name: C2C12 cell
namespace: BrendaTissueOBO
def: "This is a subclone (produced by H. Blau, et al) of the mouse myoblast cell line established by D. Yaffe and O. Saxel. The C2C12 cell line differentiates rapidly, forming contractile myotubes and producing characteristic muscle proteins. Treatment with bone morphogenic protein 2 (BMP-2) cause a shift in the differentiation pathway from myoblastic to osteoblastic. " [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000256 ! myoblast cell line

[Term]
id: BTO:0000166
name: cecum
namespace: BrendaTissueOBO
def: "The first part of the large intestine, forming a dilated pouch into which open the ileum, colon, and appendix vermiformis." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "blind intestine" RELATED []
synonym: "blindgut" RELATED []
synonym: "caecum" RELATED []
synonym: "intestinum caecum" RELATED []
relationship: part_of BTO:0000706 ! large intestine
relationship: part_of BTO:0002273 ! ileocecum

[Term]
id: BTO:0000167
name: adenocarcinoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000297 ! carcinoma cell line
relationship: DRV BTO:0000604 ! adenocarcinoma cell

[Term]
id: BTO:0000168
name: carotid artery
namespace: BrendaTissueOBO
def: "A key artery located in the front of the neck that carries blood from the heart to the brain. Cholesterol plaques on the inner wall of the carotid artery can lead to stroke." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0000573 ! artery
relationship: part_of BTO:0000420 ! neck

[Term]
id: BTO:0000169
name: calyx
namespace: BrendaTissueOBO
def: "The usually green outer whorl of a flower consisting of sepals." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=calyx]
synonym: "GRO:0005653" RELATED []
relationship: part_of BTO:0001727 ! perianth

[Term]
id: BTO:0000170
name: cambium
namespace: BrendaTissueOBO
def: "A thin formative layer between the xylem and phloem of most vascular plants that gives rise to new cells and is responsible for secondary growth;\nA lateral meristem in vascular plants, including the vascular cambium and cork cambium, that forms parallel rows of cells resulting in secondary tissues." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cambium, The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "GRO:0005597" RELATED []
relationship: DRV BTO:0001119 ! procambium
relationship: part_of BTO:0001188 ! root
relationship: part_of BTO:0001299 ! stele

[Term]
id: BTO:0000171
name: L-cell
namespace: BrendaTissueOBO
def: "A cultured line of C3H mouse FIBROBLASTS that do not adhere to one another and do not express CADHERINS." [Medical Dictionary Online:http\://www.online-medical-dictionary.org/]
is_a: BTO:0000453 ! fibroblast cell line

[Term]
id: BTO:0000172
name: pileus
namespace: BrendaTissueOBO
def: "The convex, concave, or flattened spore-bearing structure of some basidiomycetes that is attached superiorly to the stem and typically is expanded with gills or pores on the underside." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pileus]
synonym: "cap" RELATED []
relationship: part_of BTO:0000487 ! fruitbody

[Term]
id: BTO:0000173
name: fruit capsule
namespace: BrendaTissueOBO
def: "A simple fruit that develops from a compound ovary with two or more carpels; capsules dehisce in many ways, example: cotton." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "plant capsule" RELATED []
is_a: BTO:0000486 ! fruit
is_a: BTO:0001287 ! sporangium

[Term]
id: BTO:0000174
name: embryonic structure
namespace: BrendaTissueOBO
def: "An anatomical structure that exists only before the organism is fully formed. In mammals, for example, a structure that exists only prior to the birth of the organism. This structure may be normal or abnormal." [Harvard Medical School:http\://dsg.harvard.edu/courses/hst952/UMLSSemanticTypes.doc]
is_a: BTO:0000284 ! organism form
is_a: BTO:0001489 ! whole body

[Term]
id: BTO:0000175
name: epithalamus
namespace: BrendaTissueOBO
def: "The caudal part of the roof and the adjoining lateral walls of the third ventricle of the diencephalon, comprising the habenular nuclei and their commissure, pineal body, and commissure of the epithalamus." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=epithalamus]
relationship: part_of BTO:0000342 ! diencephalon

[Term]
id: BTO:0000176
name: carcinoma cell
namespace: BrendaTissueOBO
def: "A cell of malignant new growth made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases." [Dorlands Medical Dictionary:MerckSource]
synonym: "basal cell epithelioma cell" RELATED []
synonym: "epithelial cancer cell" RELATED []
synonym: "epithelial carcinoma cell" RELATED []
synonym: "malignant epithelioma cell" RELATED []
is_a: BTO:0000415 ! epithelioma cell

[Term]
id: BTO:0000177
name: BG-1 cell
namespace: BrendaTissueOBO
def: "Ovarian adenocarcinoma cell line." [PMID:11578462]
synonym: "BG1 cell" RELATED []
is_a: BTO:0001882 ! ovary adenocarcinoma cell line

[Term]
id: BTO:0000178
name: adenoma cell
namespace: BrendaTissueOBO
def: "A benign epithelial tumor cell in which the cells form recognizable glandular structures or in which the cells are clearly derived from glandular epithelium." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000415 ! epithelioma cell

[Term]
id: BTO:0000179
name: Colo-205 cell
namespace: BrendaTissueOBO
def: "Human Caucasian colon adenocarcinoma cell line. Isolated from ascitic fluid of a 70-year-old Caucasian male with carcinoma of the colon." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "Colo205 cell" RELATED []
is_a: BTO:0001913 ! colonic adenocarcinoma cell line

[Term]
id: BTO:0000180
name: cervical carcinoma cell
namespace: BrendaTissueOBO
def: "A cancer cell of the uterine cervix (the neck of the uterus)." [The Cancer Information Network \, Medical Terms Used In Oncology:http\://www.cancerlinksusa.com/tools/glossary.htm]
synonym: "carcinoma cell, cervical" RELATED []
synonym: "carcinoma cell. cervix" RELATED []
synonym: "cervical cancer cell" RELATED []
synonym: "cervix carcinoma cell" RELATED []
is_a: BTO:0001421 ! uterine cervix

[Term]
id: BTO:0000181
name: Lewis lung carcinoma cell line
namespace: BrendaTissueOBO
synonym: "LLC cell line" RELATED []
is_a: BTO:0000762 ! lung cancer cell line
relationship: DRV BTO:0000745 ! Lewis lung carcinoma cell

[Term]
id: BTO:0000182
name: HT-29 cell
namespace: BrendaTissueOBO
def: "Human colon adenocarcinoma, established from the primary tumor of a 44-year-old Caucasian woman with colon adenocarcinoma in 1964; described to be heterotransplantable forming well-differentiated grade I tumors." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0001913 ! colonic adenocarcinoma cell line

[Term]
id: BTO:0000183
name: pancreatic cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000988 ! pancreas

[Term]
id: BTO:0000184
name: medullary thyroid carcinoma cell
namespace: BrendaTissueOBO
def: "A cell ot a type of thyroid gland carcinoma that contains amyloid deposits and parafollicular cells and secretes calcitonin. It occurs in both an autosomal dominant form as a component of multiple endocrine neoplasia, types II and III, and in a nonfamilial form." [Dorlands Medical Dictionary:MerckSource]
synonym: "medullary carcinoma cell of thyroid gland" RELATED []
synonym: "MTC cell" RELATED []
synonym: "thyroid carcinoma cell, medullary" RELATED []
is_a: BTO:0000191 ! medullary carcinoma cell
is_a: BTO:0000196 ! thyroid cancer cell

[Term]
id: BTO:0000185
name: medullary breast carcinoma cell
namespace: BrendaTissueOBO
def: "A cell of a rare type of breast cancer that often can be treated successfully. It is marked by lymphocytes (a type of white blood cell) in and around the tumor that can be seen when viewed under a microscope.  " [Glossary of Cancer terms:http\://www.webref.org/cancer/m/medullary_breast_carcinoma.htm]
is_a: BTO:0000150 ! breast cancer cell
is_a: BTO:0000191 ! medullary carcinoma cell

[Term]
id: BTO:0000186
name: lobular carcinoma cell
namespace: BrendaTissueOBO
def: "A cell of an infiltrating (invasive) breast cancer, relatively uncommon, accounting for only 5%-10% of breast tumours in most series. It is often an area of ill-defined thickening in the breast, in contrast to the dominant lump characteristic of ductal carcinoma. It is typically composed of small cells in a linear arrangement with a tendency to grow around ducts and lobules. There is likelihood of axillary nodal involvement with metastasis to meningeal and serosal surfaces. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0000150 ! breast cancer cell

[Term]
id: BTO:0000187
name: myeloblast
namespace: BrendaTissueOBO
def: "A large mononuclear nongranular bone-marrow cell; especially: one that is a precursor of a myelocyte." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=myeloblast]
relationship: part_of BTO:0000141 ! bone marrow

[Term]
id: BTO:0000188
name: colonic cell line
namespace: BrendaTissueOBO
is_a: BTO:0000003 ! intestinal cell line
relationship: DRV BTO:0000269 ! colon

[Term]
id: BTO:0000189
name: small cell lung cancer cell
namespace: BrendaTissueOBO
def: "A cell of a common, highly malignant form of bronchogenic carcinoma in the wall of a major bronchus, occurring mainly in middle-aged individuals with a history of tobacco smoking; it is radiosensitive and has small oval undifferentiated cells that are intensely hematoxyphilic. Metastasis to the hilum and to mediastinal lymph nodes is common. " [Dorlands Medical Dictionary:MerckSource]
synonym: "SCLC cell" RELATED []
synonym: "small cell carcinoma cell" RELATED []
synonym: "small cell lung carcinoma cell" RELATED []
is_a: BTO:0002061 ! bronchogenic carcinoma cell

[Term]
id: BTO:0000190
name: Ehrlich tumor carcinoma cell
namespace: BrendaTissueOBO
def: "A Ehrlich tumor carcinoma is a transplantable, poorly differentiated malignant tumour  which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0000150 ! breast cancer cell

[Term]
id: BTO:0000191
name: medullary carcinoma cell
namespace: BrendaTissueOBO
def: "A cell of a carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "carcinoma molle cell" RELATED []
synonym: "carcinoma spongiosum cell" RELATED []
synonym: "cerebriform cancer cell" RELATED []
synonym: "cerebriform carcinoma cell" RELATED []
synonym: "encephaloid cancer cell" RELATED []
synonym: "soft cancer cell" RELATED []
is_a: BTO:0000176 ! carcinoma cell

[Term]
id: BTO:0000192
name: nasopharyngeal carcinoma cell
namespace: BrendaTissueOBO
def: "A cell of a disease in which cancer (malignant) cells are found in the tissues of the nasopharynx." [The Cancer Center at Saint Mary's Mercy Medical Center \, Glossary of Terms:http\://www.smcancercenter.com/resource/n.shtml]
synonym: "carcinoma cell, nasopharynx" RELATED []
synonym: "nasopharyngeal cancer cell" RELATED []
synonym: "nasopharynx cancer cell" RELATED []
synonym: "nasopharynx carcinoma cell" RELATED []
is_a: BTO:0000176 ! carcinoma cell
relationship: DRV BTO:0000662 ! nasopharynx

[Term]
id: BTO:0000193
name: rectal cancer cell
namespace: BrendaTissueOBO
def: "Cancer cell of the rectum." [Atlas of Gastroenterological Endoscopy:http\://www.endoskopischer-atlas.de/lexe.htm]
synonym: "carcinoma cell, rectal" RELATED []
synonym: "rectal carcinoma cell" RELATED []
relationship: DRV BTO:0001158 ! rectum

[Term]
id: BTO:0000194
name: endometrioid carcinoma cell
namespace: BrendaTissueOBO
def: "Ovarian carcinoma cell which resembles typical carcinoma of the endometrium and may be seen with a synchronous endometrial carcinoma. When they appear together, both tend to be of low stage. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0001023 ! ovary cancer cell
relationship: DRV BTO:0001422 ! uterine endometrium

[Term]
id: BTO:0000195
name: CACO-2 cell
namespace: BrendaTissueOBO
def: "Human colon adenocarcinoma cell line, established from the primary colon tumor (adenocarcinoma) of a 72-year-old Caucasian man in 1974." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "Caco-2 cell" RELATED []
is_a: BTO:0001913 ! colonic adenocarcinoma cell line

[Term]
id: BTO:0000196
name: thyroid cancer cell
namespace: BrendaTissueOBO
def: "Cancer cell of the thyroid gland." [Aristoteles University of Thessaloniki \, Dictionary of Medical Terms:http\://www.med.auth.gr/db/dictionary1/gr/]
synonym: "carcinoma cell, thyroid" RELATED []
synonym: "thyroid carcinoma cell" RELATED []
relationship: DRV BTO:0001379 ! thyroid gland

[Term]
id: BTO:0000197
name: carcinosarcoma cell
namespace: BrendaTissueOBO
def: "A cell of a malignant tumor that is a mixture of carcinoma (cancer of epithelial tissue, which is skin and tissue that lines or covers the internal organs) and sarcoma (cancer of connective tissue, such as bone, cartilage, and fat).  " [Medical Dictionary \, Hyperdictionary:http\://www.hyperdictionary.com/medical/carcinosarcoma]
is_a: BTO:0000176 ! carcinoma cell
is_a: BTO:0001207 ! sarcoma cell

[Term]
id: BTO:0000198
name: cardia
namespace: BrendaTissueOBO
def: "The opening of the esophagus into the stomach; also: the part of the stomach adjoining this opening." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cardia]
relationship: part_of BTO:0000959 ! esophagus

[Term]
id: BTO:0000199
name: cardiac muscle
namespace: BrendaTissueOBO
def: "The principal muscle tissue of the vertebrate heart made up of striated fibers that appear to be separated from each other under the electron microscope but that function in long-term rhythmic contraction as if in protoplasmic continuity." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cardiac+muscle]
synonym: "heart muscle" RELATED []
relationship: part_of BTO:0000562 ! heart
relationship: part_of BTO:0001369 ! vertebrate muscular system

[Term]
id: BTO:0000200
name: culture condition:2-chloropropionate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000201
name: pheochromocytoma cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001054 ! pheochromocytoma cell

[Term]
id: BTO:0000202
name: sense organ
namespace: BrendaTissueOBO
def: "A bodily structure that receives a stimulus (as heat or sound waves) and is affected in such a manner as to initiate a wave of excitation in associated sensory nerve fibers which convey specific impulses to the central nervous system where they are interpreted as corresponding sensations: RECEPTOR." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sense+organ]
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000203
name: respiratory system
namespace: BrendaTissueOBO
def: "A system of organs subserving the function of respiration and in air-breathing vertebrates consisting typically of the lungs and their nervous and circulatory supply and the channels by which these are continuous with the outer air." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=respiratory+system]
synonym: "respiratory tract" RELATED []
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000204
name: carotid body
namespace: BrendaTissueOBO
def: "A small cluster of chemoreceptive and supporting cells located near the bifurcation of the internal carotid artery. The carotid body, which is richly supplied with fenestrated capillaries, senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0000202 ! sense organ
relationship: part_of BTO:0000168 ! carotid artery

[Term]
id: BTO:0000205
name: nerve plexus
namespace: BrendaTissueOBO
def: "A plexus made up of intermingled nerve fibers." [Dorlands Medical Dictionary:MerckSource]
relationship: DRV BTO:0000925 ! nerve

[Term]
id: BTO:0000206
name: cartilage
namespace: BrendaTissueOBO
def: "A specialized, fibrous connective tissue, forming most of the temporary skeleton of the embryo, providing a model in which most of the bones develop, and constituting an important part of the growth mechanism of the organism. It exists in several types, the most important of which are hyaline cartilage, elastic cartilage, and fibrocartilage. Also used as a general term to designate a mass of such tissue in a particular site in the body. " [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000421 ! connective tissue
relationship: part_of BTO:0001486 ! skeletal system

[Term]
id: BTO:0000207
name: tibial cartilage
namespace: BrendaTissueOBO
def: "Cartilage pertaining to the tibia." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000206 ! cartilage
is_a: BTO:0001252 ! tibia

[Term]
id: BTO:0000208
name: caryopsis
namespace: BrendaTissueOBO
def: "Simple, dry, indehiscent fruit with a single seed that is fused to the ovary wall, example: wheat." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "grain" RELATED []
is_a: BTO:0000486 ! fruit

[Term]
id: BTO:0000209
name: corpus epididymis
namespace: BrendaTissueOBO
def: "The body of the epididymis." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000408 ! epididymis

[Term]
id: BTO:0000210
name: cauda epididymis
namespace: BrendaTissueOBO
def: "The tail of the epididymis." [Dorlands Medical Dictionary:MerckSource]
synonym: "epididymal cauda" RELATED []
relationship: part_of BTO:0000408 ! epididymis

[Term]
id: BTO:0000211
name: caudate nucleus
namespace: BrendaTissueOBO
def: "One of the centrally-located portions of the brain affected by Huntington's Disease. Speech and swallowing problems arise when this region and another region called the putamen are affected." [Dictionary of Huntington's Disease (HD) Terms:http\://www.hdsa-wi.org/dictionary.htm]
relationship: part_of BTO:0000418 ! neostriatum
relationship: part_of BTO:0001311 ! corpus striatum

[Term]
id: BTO:0000212
name: caudate putamen
namespace: BrendaTissueOBO
def: "A centrally-located portion of the brain affected by Huntington's Disease. The putamen is structurally similar to the caudate nucleus together with which it composes what is termed the striatum." [Dictionary of Huntington's Disease (HD) Terms:http\://www.hdsa-wi.org/dictionary.htm]
relationship: part_of BTO:0000418 ! neostriatum
relationship: part_of BTO:0002250 ! nucleus lentiformis

[Term]
id: BTO:0000213
name: cecum mucosa
namespace: BrendaTissueOBO
is_a: BTO:0000642 ! intestinal mucosa
relationship: part_of BTO:0000166 ! cecum

[Term]
id: BTO:0000214
name: cell culture
namespace: BrendaTissueOBO
def: "Cells taken from a living organism and grown under controlled conditions (in culture). Methods used to maintain cell lines or strains." [Glossary of Fermentation & Cell Culture Terms:http\://www.nbsc.com/files/papers/bp0600_gloss_36-44.pdf]
is_a: BTO:0001490 ! other source

[Term]
id: BTO:0000215
name: culture condition:galactonate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000216
name: culture condition
namespace: BrendaTissueOBO
relationship: part_of BTO:0000214 ! cell culture

[Term]
id: BTO:0000217
name: MH-7777A cell
namespace: BrendaTissueOBO
def: "Rat hepatoma, established from the liver tumor of a Buffalo rat; tumor cells were propagated in the hind leg." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000218
name: BALB/3T3 cell
namespace: BrendaTissueOBO
def: "The BALB/3T3 clone A31 is one of several cell lines (see BALB/3T12) developed in 1968 from disaggregated 14- to 17-day-old BALB/c mouse embryos." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "BALB/3T3 clone A31" RELATED []
synonym: "BALBc/3T3 cell" RELATED []
is_a: BTO:0001958 ! embryonic fibroblast cell line

[Term]
id: BTO:0000219
name: MH-3924 cell
namespace: BrendaTissueOBO
def: "Rat Morris hepatoma cell line." [PMID:12798353, PMID:3716925]
synonym: "MH3924 cell" RELATED []
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000220
name: MH1C1 cell
namespace: BrendaTissueOBO
def: "Rat hepatoma, a clonal strain of epithelial cells was derived from a transplantable Morris hepatoma (#7795, Buffalo strain) in 1967; cells were described to synthesize and to secrete serum albumin and serum complement component C9." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "MH 1 C 1 cell" RELATED []
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000221
name: cell suspension culture
namespace: BrendaTissueOBO
def: "Particles floating in (not necessarily on) a liquid medium, or the mix of particles and liquid itself." [Glossary of Fermentation & Cell Culture Terms:http\://www.nbsc.com/files/papers/bp0600_gloss_36-44.pdf]
is_a: BTO:0000214 ! cell culture

[Term]
id: BTO:0000222
name: myoblast
namespace: BrendaTissueOBO
def: "An embryonic cell that becomes a cell of muscle fiber." [Dorlands Medical Dictionary:MerckSource]
synonym: "sarcoblast" RELATED []
relationship: part_of BTO:0000379 ! embryo

[Term]
id: BTO:0000223
name: teratocarcinoma cell
namespace: BrendaTissueOBO
def: "A malignant tumor cell of the testis composed of teratoma and embryonal carcinoma." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000279 ! testicular cancer cell

[Term]
id: BTO:0000224
name: liver cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000759 ! liver

[Term]
id: BTO:0000225
name: CEM cell
namespace: BrendaTissueOBO
def: "CEM is a camptothecin (CPT) resistant derivative of the human T cell leukemia cell line CCRF-CEM. The cell line was selected and subcloned in 1991 for resistance to CPT. Established from an 4-year-old caucasian female." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
relationship: DRV BTO:0000736 ! CCRF-CEM cell

[Term]
id: BTO:0000226
name: gitter cell
namespace: BrendaTissueOBO
def: "A microglial cell that is globular and swollen after having phagocytized debris from cells destroyed pathologically in the central nervous system." [Dorlands Medical Dictionary:MerckSource]
synonym: "compound granular corpuscle" RELATED []
synonym: "compound granule cell" RELATED []
is_a: BTO:0000078 ! microglia

[Term]
id: BTO:0000227
name: central nervous system
namespace: BrendaTissueOBO
def: "The central nervous system is that part of the nervous system that consists of the brain and spinal cord. The central nervous system (CNS) is one of the two major divisions of the nervous system. The other is the peripheral nervous system (PNS) which is outside the brain and spinal cord. " [Medical Dictionary:http\://www.medterms.com/]
synonym: "CNS" RELATED []
relationship: part_of BTO:0001484 ! nervous system

[Term]
id: BTO:0000228
name: C-1300 cell
namespace: BrendaTissueOBO
def: "Mouse neuroblastoma cell line." [PMID:11579158]
synonym: "C1300 cell" RELATED []
is_a: BTO:0000932 ! neuroblastoma cell line

[Term]
id: BTO:0000229
name: centrum semiovale
namespace: BrendaTissueOBO
def: "The white matter of the cerebral hemispheres which underlies the cerebral cortex and which, in horizontal sections superior to the corpus callosum, has a semioval shape; it contains projection, commissural, and association fibers." [Dorlands Medical Dictionary:MerckSource]
synonym: "semioval center" RELATED []
relationship: part_of BTO:0000236 ! cerebral white matter

[Term]
id: BTO:0000230
name: subarachnoid space
namespace: BrendaTissueOBO
def: "The space between the arachnoidea mater and the pia mater, containing cerebrospinal fluid and bridged by delicate trabeculae." [Dorlands Medical Dictionary:MerckSource]
synonym: "cavitas subarachnoidea" RELATED []
synonym: "spatium leptomeningeum" RELATED []
synonym: "spatium subarachnoideum" RELATED []
synonym: "subarachnoid cavity" RELATED []
relationship: part_of BTO:0000818 ! spinal column

[Term]
id: BTO:0000231
name: cerebral hemisphere
namespace: BrendaTissueOBO
def: "Either of the two hollow convoluted lateral halves of the cerebrum." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cerebral+hemisphere]
relationship: part_of BTO:0000239 ! telencephalon

[Term]
id: BTO:0000232
name: cerebellum
namespace: BrendaTissueOBO
def: "A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cerebellum]
relationship: part_of BTO:0000673 ! metencephalon

[Term]
id: BTO:0000233
name: cerebral cortex
namespace: BrendaTissueOBO
def: "The surface layer of gray matter of the cerebrum that functions chiefly in coordination of sensory and motor information." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cerebral+cortex]
synonym: "brain cortex" RELATED []
relationship: part_of BTO:0000231 ! cerebral hemisphere

[Term]
id: BTO:0000234
name: vein
namespace: BrendaTissueOBO
def: "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=vein]
is_a: BTO:0001102 ! blood vessel

[Term]
id: BTO:0000235
name: basal ganglion
namespace: BrendaTissueOBO
def: "Any of four deeply placed masses of gray matter (as the amygdala) in each cerebral hemisphere. Location: The basal ganglion is located deep within the cerebral hemispheres in the telencephalon region of the brain. It consists of the corpus stratium, subthalamic nucleus and the substantia nigra. " [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=basal+ganglion]
synonym: "basal nucleus" RELATED []
is_a: BTO:0000497 ! ganglion
relationship: part_of BTO:0000233 ! cerebral cortex

[Term]
id: BTO:0000236
name: cerebral white matter
namespace: BrendaTissueOBO
def: "Whitish nerve tissue, especially of the brain and spinal cord, consisting chiefly of myelinated nerve fibers." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "white matter" RELATED []
relationship: part_of BTO:0000142 ! brain
relationship: part_of BTO:0001279 ! spinal cord

[Term]
id: BTO:0000237
name: cerebrospinal fluid
namespace: BrendaTissueOBO
def: "The serumlike fluid that circulates through the ventricles of the brain, the cavity of the spinal cord, and the subarachnoid space, functioning in shock absorption." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "cerebral spinal fluid" RELATED []
synonym: "CSF" RELATED []
synonym: "spinal fluid" RELATED []
relationship: DRV BTO:0000258 ! choroid plexus
relationship: part_of BTO:0000230 ! subarachnoid space
relationship: part_of BTO:0001279 ! spinal cord

[Term]
id: BTO:0000238
name: cerebrovascular endothelial cell
namespace: BrendaTissueOBO
def: "Endothelial cell of or involving the cerebrum and the blood vessels supplying it." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cerebrovascular]
is_a: BTO:0001854 ! vascular endothelial cell
relationship: part_of BTO:0000239 ! telencephalon
relationship: part_of BTO:0001852 ! cerebrovascular endothelium

[Term]
id: BTO:0000239
name: telencephalon
namespace: BrendaTissueOBO
def: "An enlarged anterior or upper part of the brain; especially: the expanded anterior portion of the brain that in higher mammals overlies the rest of the brain, consists of cerebral hemispheres and connecting structures, and is considered to be the seat of conscious mental processes." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=telencephalon]
synonym: "cerebrum" RELATED []
relationship: part_of BTO:0000478 ! forebrain

[Term]
id: BTO:0000240
name: inferior cervical ganglion
namespace: BrendaTissueOBO
def: "An inconstant ganglion formed in place of the usual cervicothoracic ganglion by fusion of the lower two cervical ganglia in instances where the first thoracic ganglion remains separate." [Dorlands Medical Dictionary:MerckSource]
synonym: "ganglion cervicale inferioris" RELATED []
is_a: BTO:0000113 ! cervical ganglion

[Term]
id: BTO:0000241
name: cervical epithelium
namespace: BrendaTissueOBO
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0001421 ! uterine cervix

[Term]
id: BTO:0000242
name: cervical mucus
namespace: BrendaTissueOBO
def: "A substance produced by the cervix and endocervical glands." [Dictionary of Terms:http\://www.dreamababy.com/dictionary.htm]
relationship: REL BTO:0001421 ! uterine cervix

[Term]
id: BTO:0000243
name: vagina
namespace: BrendaTissueOBO
def: "A canal in a female mammal that leads from the uterus to the external orifice of the genital canal." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=vagina]
is_a: BTO:0003099 ! internal female genital organ
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0000244
name: culture condition:chlorobenzene-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000245
name: culture condition:chlorobenzoate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000246
name: CHO cell
namespace: BrendaTissueOBO
def: "Chinese hamster ovary cell line, that was initiated from an ovary biopsy of an adult Chinese hamster in 1957." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000977 ! ovary cell line

[Term]
id: BTO:0000247
name: shoot tip
namespace: BrendaTissueOBO
def: "The terminal bud (0.1 - 1.0 mm) of a plant, which consists of the apical meristem (0.05 - 0.1 mm) and the immediate surrounding leaf primordia and developing leaves and adjacent stem tissue." [Dictionary of Genomics (Japan):http\://cny.new21.net/dictionary/s-e.html]
synonym: "GRO:0000370" RELATED []
synonym: "shoot apex" RELATED []
relationship: part_of BTO:0001243 ! shoot

[Term]
id: BTO:0000248
name: chondroclast
namespace: BrendaTissueOBO
def: "A giant cell of the class that is believed associated with the absorption of cartilage." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000801 ! macrophage
relationship: part_of BTO:0000206 ! cartilage

[Term]
id: BTO:0000249
name: chondrocyte
namespace: BrendaTissueOBO
def: "Cartilage cells. They make the structural components of cartilage." [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "cartilage cell" RELATED []
is_a: BTO:0000206 ! cartilage

[Term]
id: BTO:0000250
name: chondrosarcoma cell
namespace: BrendaTissueOBO
def: "Chondrosarcoma is a malignant tumor derived from cartilage cells or their precursors, but lacking direct osteoid formation; it occurs predominantly in the pelvis, femur, and shoulder girdle in middle-aged to older adults. It may be primary, arising from cartilage cells, or secondary to a pre-existing benign lesion." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000372 ! bone cancer cell
is_a: BTO:0001207 ! sarcoma cell

[Term]
id: BTO:0000251
name: chorioallantois
namespace: BrendaTissueOBO
def: "A vascular fetal membrane composed of the fused chorion and adjacent wall of the allantois that in the hen's egg is used as a living culture medium for viruses and for tissues." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=chorioallantois]
synonym: "chorioallantoic membrane" RELATED []
is_a: BTO:0000473 ! fetal membrane

[Term]
id: BTO:0000252
name: chorion
namespace: BrendaTissueOBO
def: "The outer membrane of the two membranes enclosing the embryo in reptiles, birds, and mammals. In placental mammals it contributes to the development of the placenta." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000473 ! fetal membrane

[Term]
id: BTO:0000253
name: BEN cell
namespace: BrendaTissueOBO
def: "Human lung carcinoma; established from the supraclavicular tumor cells-containing lymph node of a 71-year-old man with poorly differentiated carcinoma of the lung." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000762 ! lung cancer cell line

[Term]
id: BTO:0000254
name: female reproductive gland
namespace: BrendaTissueOBO
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0000255
name: brain cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000142 ! brain

[Term]
id: BTO:0000256
name: myoblast cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000222 ! myoblast

[Term]
id: BTO:0000257
name: uterine cancer cell
namespace: BrendaTissueOBO
relationship: DRV BTO:0001424 ! uterus

[Term]
id: BTO:0000258
name: choroid plexus
namespace: BrendaTissueOBO
def: "The choroid plexus is tissue located in the spaces inside the brain called ventricles. The choroid plexus makes the fluid that fills the ventricles and surrounds the brain and spinal cord." [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
relationship: part_of BTO:0001442 ! brain ventricle

[Term]
id: BTO:0000259
name: chromaffin cell
namespace: BrendaTissueOBO
def: "A type of amine precursor uptake and decarboxylation cells that stain readily with chromium salts, their cytoplasmic granules taking on a characteristic brown color; they are found especially in cells of the adrenal medulla and in paraganglia of the coccygeal gland and carotid gland, along the sympathetic nerves, and in various organs. They contain chromaffin granules. " [Dorlands Medical Dictionary:MerckSource]
synonym: "pheochrome cell" RELATED []
synonym: "pheochromocytes" RELATED []
relationship: part_of BTO:0000049 ! adrenal medulla

[Term]
id: BTO:0000260
name: ciliary body
namespace: BrendaTissueOBO
def: "Tissue that includes the group of muscles that act on the eye lens to produce accommodation and the arterial circle of the iris. The inner ciliary epithelium is continuous with the pigmented retinal epithelium, the outer ciliary epithelium secretes the aqueous humour." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000439 ! eye

[Term]
id: BTO:0000261
name: culture condition:mannitol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000262
name: clove
namespace: BrendaTissueOBO
def: "One of the small bulbs (as in garlic) developed in the axils of the scales of a large bulb." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=clove]
is_a: BTO:0000159 ! bulb

[Term]
id: BTO:0000263
name: P-388D1(IL-1) cell
namespace: BrendaTissueOBO
def: "Mouse monocytes-macrophages, established from the ascites of a DBA/2 mouse with a lymphoid neoplasm induced by methylcholanthrene and subsequently enriched for adherent (monocyte-macrophage) cells by selection (yielding this IL1-producing subclone); reported to produce IL-1 after stimulation with LPS or PMA, to phagocytize latex articles and to synthesize lysozyme." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000984 ! P-388D1 cell

[Term]
id: BTO:0000264
name: bone marrow cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000141 ! bone marrow

[Term]
id: BTO:0000265
name: coagulating gland
namespace: BrendaTissueOBO
is_a: BTO:0000080 ! male reproductive gland

[Term]
id: BTO:0000266
name: cob
namespace: BrendaTissueOBO
def: "The central axis/core of the ear (distal end of the lateral branch/ear shoot) upon which the kernels (caryopses) are borne. The cob is similar to the central spike of the tassel (male inflorescence) in that it produces multiple rows of paired spikelets (polystichous phyllotaxy)." [Maize DB:http\://www.maizemap.org/MMP_Downloads/POC/Zea_mays_anatomy_ontology_definitions.txt]
comment: Zea mays.
synonym: "GRO:0005440" RELATED []
is_a: BTO:0001278 ! spike

[Term]
id: BTO:0000267
name: cochlea
namespace: BrendaTissueOBO
def: "A division of the bony labyrinth of the inner ear of higher vertebrates that is usually coiled like a snail shell and is the seat of the hearing organ." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cochlea]
relationship: part_of BTO:0003381 ! vestibular system

[Term]
id: BTO:0000268
name: coleoptile
namespace: BrendaTissueOBO
def: "The first leaf of a monocotyledon forming a protective sheath about the plumule." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=coleoptile]
synonym: "GRO:0005373" RELATED []
relationship: part_of BTO:0001495 ! plumule

[Term]
id: BTO:0000269
name: colon
namespace: BrendaTissueOBO
def: "The part of the large intestine that extends from the cecum to the rectum." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=colon]
relationship: part_of BTO:0000706 ! large intestine
relationship: part_of BTO:0001613 ! colorectum

[Term]
id: BTO:0000270
name: colon ascendens
namespace: BrendaTissueOBO
def: "The portion of the colon between the cecum and the right colic flexure." [Dorlands Medical Dictionary:MerckSource]
synonym: "ascending colon" RELATED []
relationship: part_of BTO:0000269 ! colon

[Term]
id: BTO:0000271
name: colonic mucosa
namespace: BrendaTissueOBO
synonym: "colon mucosa" RELATED []
is_a: BTO:0000642 ! intestinal mucosa
relationship: part_of BTO:0000269 ! colon

[Term]
id: BTO:0000272
name: colon transversum
namespace: BrendaTissueOBO
def: "The portion of the colon that runs transversely across the upper part of the abdomen, from the right to the left colic flexure." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000269 ! colon

[Term]
id: BTO:0000273
name: ink gland
namespace: BrendaTissueOBO
def: "The ink gland and ink sac are specializations of the rectal gland. " [The Columbia Encyclopedia:Sixth Edition. 2001]
is_a: BTO:0001157 ! rectal gland

[Term]
id: BTO:0000274
name: apical bud
namespace: BrendaTissueOBO
def: "The uppermost bud on a stem." [Glossary of Gardening Terms:http\://www.geocities.com/impatients63/DictB.htm]
synonym: "terminal bud" RELATED []
is_a: BTO:0000158 ! plant bud

[Term]
id: BTO:0000275
name: colonocyte
namespace: BrendaTissueOBO
relationship: REL BTO:0000305 ! crypt

[Term]
id: BTO:0000276
name: colostrum
namespace: BrendaTissueOBO
def: "Milk secreted for a few days after parturition and characterized by high protein and antibody content." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=colostrum]
is_a: BTO:0000868 ! milk

[Term]
id: BTO:0000277
name: columnella muscle
namespace: BrendaTissueOBO
def: "The muscle of the central column or axis of a spiral univalve shell." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=columella]
synonym: "columella muscle" RELATED []
is_a: BTO:0001262 ! soft body part
relationship: part_of BTO:0001266 ! invertebrate muscular system

[Term]
id: BTO:0000278
name: commercial preparation
namespace: BrendaTissueOBO
synonym: "commercial product" RELATED []
is_a: BTO:0001490 ! other source

[Term]
id: BTO:0000279
name: testicular cancer cell
namespace: BrendaTissueOBO
def: "Cancer that forms in tissues of the testis. Testicular cancer usually occurs in young or middle-aged men. Two main types of testicular cancer are seminomas (cancers that grow slowly and are sensitive to radiation therapy) and nonseminomas (different cell types that grow more quickly than seminomas)." [Dictionary of Cancer Terms:http\://www.cancer.gov/]
synonym: "testicular carcinoma cell" RELATED []
relationship: DRV BTO:0001363 ! testis

[Term]
id: BTO:0000280
name: cone
namespace: BrendaTissueOBO
def: "A mass of ovule-bearing or pollen-bearing scales or bracts in trees of the pine family or in cycads that are arranged usually on a somewhat elongated axis." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cone]
is_a: BTO:0000469 ! flower

[Term]
id: BTO:0000281
name: conidiophore
namespace: BrendaTissueOBO
def: "A specialized fungal hypha that produces conidia." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000612 ! hypha

[Term]
id: BTO:0000282
name: head
namespace: BrendaTissueOBO
def: "The upper or anterior division of the animal body that contains the brain, the chief sense organs, and the mouth." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=head]
relationship: part_of BTO:0001493 ! trunk

[Term]
id: BTO:0000283
name: conidium
namespace: BrendaTissueOBO
def: "An asexual spore produced on a conidiophore." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=conidium]
synonym: "conidiospore" RELATED []
is_a: BTO:0001171 ! spore
relationship: part_of BTO:0000281 ! conidiophore

[Term]
id: BTO:0000284
name: organism form
namespace: BrendaTissueOBO
is_a: BTO:0001489 ! whole body

[Term]
id: BTO:0000285
name: corm
namespace: BrendaTissueOBO
def: "A rounded thick modified underground stem base bearing membranous or scaly leaves and buds and acting as a vegetative reproductive structure." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=corm]
synonym: "GRO:0005787" RELATED []
is_a: BTO:0000720 ! plant form
is_a: BTO:0001300 ! stem

[Term]
id: BTO:0000286
name: cornea
namespace: BrendaTissueOBO
def: "The transparent part of the coat of the eyeball that covers the iris and pupil and admits light to the interior." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cornea]
relationship: part_of BTO:0000439 ! eye

[Term]
id: BTO:0000287
name: corneal epithelium
namespace: BrendaTissueOBO
def: "Posterior epithelium of cornea: the mesothelial layer covering the posterior surface of the posterior limiting lamina of the cornea; it was once believed to extend to the anterior surface of the stroma of the iris." [Dorlands Medical Dictionary:MerckSource]
synonym: "anterior endothelium of cornea" RELATED []
synonym: "corneal endothelium" RELATED []
synonym: "endothelium anterius corneae" RELATED []
synonym: "endothelium camerae anterioris bulbi" RELATED []
synonym: "endothelium corneale" RELATED []
synonym: "epithelium posterius corneae" RELATED []
relationship: part_of BTO:0000286 ! cornea

[Term]
id: BTO:0000288
name: corona
namespace: BrendaTissueOBO
def: "An appendage or series of united appendages on the inner side of the corolla in some flowers (as the daffodil, jonquil, or milkweed)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=corona]
synonym: "paracorolla" RELATED []
relationship: part_of BTO:0000163 ! corolla

[Term]
id: BTO:0000289
name: cytotoxic T-cell
namespace: BrendaTissueOBO
def: "Subset of T-lymphocytes (mostly CD8+) responsible for lysing target cells and for killing virus-infected cells." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "CTL" RELATED []
synonym: "cytolytic T-cell" RELATED []
synonym: "cytolytic T-lymphocyte" RELATED []
synonym: "cytotoxic T-lymphocyte" RELATED []
synonym: "killer T-cell" RELATED []
synonym: "killer T-lymphocyte" RELATED []
is_a: BTO:0000782 ! T-lymphocyte

[Term]
id: BTO:0000290
name: coronary artery
namespace: BrendaTissueOBO
def: "Either of two arteries that arise one from the left and one from the right side of the aorta immediately above the semilunar valves and supply the tissues of the heart itself." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=coronary+artery]
is_a: BTO:0000573 ! artery

[Term]
id: BTO:0000291
name: corpus allatum
namespace: BrendaTissueOBO
def: "One of a pair of separate or fused bodies in many insects that are sometimes closely associated with the corpora cardiaca and that secrete hormones (as juvenile hormone)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=allatum]
synonym: "corpora allata" RELATED []
is_a: BTO:0001488 ! endocrine gland
is_a: BTO:0001803 ! retrocerebral complex

[Term]
id: BTO:0000292
name: corpus luteum
namespace: BrendaTissueOBO
def: "A yellowish mass of progesterone-secreting endocrine tissue that forms immediately after ovulation from the ruptured graafian follicle in the mammalian ovary." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=corpus+luteum]
synonym: "luteal gland" RELATED []
is_a: BTO:0000389 ! mature ovarian follicle

[Term]
id: BTO:0000293
name: occipital lobe
namespace: BrendaTissueOBO
def: "This lobe is located at the back of the head and is involved in vision and reading." [Princeton University \, Department of Molecular Biology:http\://www.molbio.princeton.edu/courses/mb427/2000/projects/0008/anatobrainmain.html]
synonym: "occipital cortex" RELATED []
relationship: part_of BTO:0000445 ! cerebral lobe

[Term]
id: BTO:0000294
name: dermis
namespace: BrendaTissueOBO
def: "The sensitive vascular inner mesodermic layer of the skin." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=dermis]
synonym: "corium" RELATED []
synonym: "cutis" RELATED []
relationship: part_of BTO:0001253 ! skin

[Term]
id: BTO:0000295
name: WEHI-3 cell
namespace: BrendaTissueOBO
def: "Mouse, BALB/c, monocyte, monocytic leukemia cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0002332 ! monocytic leukemia cell line

[Term]
id: BTO:0000296
name: SW-1088 cell
namespace: BrendaTissueOBO
def: "Brain astrocytoma cell line. The SW 1088 cell line was initiated by A. Leibovitz at the Scott and White Clinic, Temple, Texas in 1975 from an astrocytoma taken from a 72 year old male Caucasian." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "SW1088 cell" RELATED []
is_a: BTO:0000101 ! astrocytoma cell line

[Term]
id: BTO:0000297
name: carcinoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0001120 ! epithelial cell line
relationship: DRV BTO:0000176 ! carcinoma cell

[Term]
id: BTO:0000298
name: COS-7 cell
namespace: BrendaTissueOBO
def: "African green monkey kidney derived from CV-1, a simian cell line (cercopithecus aethiops), by transformation with an origin-defective mutant of SV-40; cells were described to support the growth of SV-40 viruses." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "COS7 cell" RELATED []
is_a: BTO:0000067 ! kidney cell line

[Term]
id: BTO:0000299
name: cotton fiber
namespace: BrendaTissueOBO
def: "Each seed of a cotton plant is surrounded with downy fiber, white or creamy in color and easily spun. The fibers flatten and twist naturally as they dry." [The Columbia Encyclopedia:Sixth Edition. 2001]
synonym: "cotton fibre" RELATED []
is_a: BTO:0000450 ! fiber
relationship: REL BTO:0001226 ! seed

[Term]
id: BTO:0000300
name: cotyledon
namespace: BrendaTissueOBO
def: "A seed leaf; the first leaf formed in a seed." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005358" RELATED []
is_a: BTO:0000713 ! leaf
relationship: DRV BTO:0001226 ! seed
relationship: part_of BTO:0001233 ! plant embryo

[Term]
id: BTO:0000301
name: crop
namespace: BrendaTissueOBO
def: "A pouched enlargement of the gullet of many birds that serves as a receptacle for food and for its preliminary maceration; also: an enlargement of the gullet of another animal (as an insect)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=crop]
relationship: part_of BTO:0001049 ! pharynx

[Term]
id: BTO:0000302
name: ring gland
namespace: BrendaTissueOBO
def: "Hormonal cells involved in the production and release of ecdysone and juvenile hormone." [East Tennessee State University \, Department of Biological Sciences \, Dr. Karl H. Joplin:http\://www.etsu.edu/biology/joplin.htm]
relationship: part_of BTO:0000291 ! corpus allatum
relationship: part_of BTO:0000432 ! corpus cardiacum
relationship: part_of BTO:0000707 ! larva
relationship: part_of BTO:0001143 ! pupa
relationship: part_of BTO:0001368 ! thorax

[Term]
id: BTO:0000303
name: crown gall
namespace: BrendaTissueOBO
def: "A disease that affects many species of plants and is caused by a bacterium (Agrobacterium tumefaciens) which forms tumorous enlargements just below the ground on the stem." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=crown+gall]
is_a: BTO:0000677 ! plant tumor tissue

[Term]
id: BTO:0000304
name: PANC-1 cell
namespace: BrendaTissueOBO
def: "Human, Caucasian, pancreas, carcinoma cell line. Established from a pancreatic carcinoma of ductal origin from a 56-year-old Caucasian male. Cells possess the type B phenotype for G6PD." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000794 ! pancreatic cancer cell line

[Term]
id: BTO:0000305
name: crypt
namespace: BrendaTissueOBO
def: "A crypt is a deep pit that protrudes down into the connective tissue surrounding the small intestine. The epithelium at the base of the crypt is the site of stem cell proliferation and the differentiated cells move upwards and are shed 3-5 days later at the tips of the villi." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000651 ! small intestine
relationship: REL BTO:0000421 ! connective tissue

[Term]
id: BTO:0000306
name: teratocarcinoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0001560 ! testicular cancer cell line
relationship: DRV BTO:0000223 ! teratocarcinoma cell

[Term]
id: BTO:0000307
name: crystalline style
namespace: BrendaTissueOBO
def: "The crystalline style, a gelatinous rod, projects into the stomach and stirs the contents as well as produces digestive enzymes to aid digestion. " [Aquaculture Curriculum Guide:http\://aquanic.org/publicat/govagen/ncae/bcccult.pdf]
comment: In mollusks, valves.
relationship: part_of BTO:0000511 ! gastrointestinal tract

[Term]
id: BTO:0000308
name: cytotoxic T-lymphocyte cell line
namespace: BrendaTissueOBO
synonym: "CTL cell line" RELATED []
is_a: BTO:0001045 ! T-lymphocyte cell line

[Term]
id: BTO:0000309
name: bundle sheath cell
namespace: BrendaTissueOBO
def: "Cells surrounding the vascular bundle in C4 plants." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005728" RELATED []
relationship: part_of BTO:0000160 ! bundle sheath

[Term]
id: BTO:0000310
name: protophloem
namespace: BrendaTissueOBO
def: "The first-formed phloem that develops from procambium, consists of narrow thin-walled cells capable of a limited amount of stretching, and is usually associated with a region of rapid growth." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=protophloem]
synonym: "GRO:0000346" RELATED []
relationship: DRV BTO:0001119 ! procambium

[Term]
id: BTO:0000311
name: culture filtrate
namespace: BrendaTissueOBO
relationship: part_of BTO:0000214 ! cell culture

[Term]
id: BTO:0000312
name: motoneuron
namespace: BrendaTissueOBO
def: "A neuron with a motor function; an efferent neuron conveying motor impulses." [Dorlands Medical Dictionary:MerckSource]
synonym: "motor neuron" RELATED []
is_a: BTO:0000938 ! neuron

[Term]
id: BTO:0000313
name: hypodermis
namespace: BrendaTissueOBO
def: "1: Subcutaneous tissue.  \n2: The outer cellular layer of the body of invertebrates which secretes the cuticular exoskeleton." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000634 ! integument

[Term]
id: BTO:0000314
name: neuroepithelium
namespace: BrendaTissueOBO
def: "1: Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue. \n2: The epithelium of the ectoderm, from which the central nervous system is developed." [Dorlands Medical Dictionary:MerckSource]
synonym: "sensory epithelium" RELATED []
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0000315 ! ectoderm

[Term]
id: BTO:0000315
name: ectoderm
namespace: BrendaTissueOBO
def: "The outer of the three germ layers of the embryo (the other two being mesoderm and endoderm). Ectoderm gives rise to epidermis and neural tissue." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000556 ! germ layer

[Term]
id: BTO:0000316
name: culture medium
namespace: BrendaTissueOBO
def: "A substance, either solid or liquid, used for the cultivation, isolation, identification, or storage of microorganisms." [Biology-Online Dictionary:http\://www.biology-online.org/dictionary/]
synonym: "growth medium" RELATED []
synonym: "medium" RELATED []
synonym: "nutrient medium" RELATED []
relationship: part_of BTO:0000214 ! cell culture

[Term]
id: BTO:0000317
name: caulonema
namespace: BrendaTissueOBO
def: "The secondary, bud-generating part of the filamentous moss protonema, typically reddish-brown, having few chloroplasts and consisting of long cells with oblique end walls." [Glossarium Polyglottum Bryoloigiae:http\://mobot.mobot.org/cgi-bin/search_vast?GLOSE=208]
relationship: part_of BTO:0001134 ! protonema

[Term]
id: BTO:0000318
name: CV-1 cell
namespace: BrendaTissueOBO
alt_id: BTO:0002653
def: "Normal kidney cell line. The CV-1 cell line was derived from the kidney of a male adult African green monkey by F.C. Jensen, et al. in March, 1964 for use in Rous sarcoma virus transformation studies." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "CV 1 cell" RELATED []
synonym: "CV1 cell" RELATED []
is_a: BTO:0000067 ! kidney cell line
is_a: BTO:0000453 ! fibroblast cell line

[Term]
id: BTO:0000319
name: culture condition:cyclohexanol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000320
name: cyst
namespace: BrendaTissueOBO
def: "A body resembling a cyst: as a \n1. capsule formed about a minute organism going into a resting or spore stage; also: this capsule with its contents.\n2. a resistant cover about a parasite produced by the parasite or the host." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cyst]
is_a: BTO:0000139 ! body wall
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0000321
name: plant cuticle
namespace: BrendaTissueOBO
def: "A thin continuous fatty or waxy film on the external surface of many higher plants that consists chiefly of cutin." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cuticle]
synonym: "GRO:0005686" RELATED []
relationship: part_of BTO:0000718 ! leaf epidermis

[Term]
id: BTO:0000322
name: cytotrophoblast
namespace: BrendaTissueOBO
def: "The cellular (inner) layer of the trophoblast. " [Dorlands Medical Dictionary:MerckSource]
synonym: "Langhans' layer" RELATED []
relationship: part_of BTO:0001079 ! trophoblast

[Term]
id: BTO:0000323
name: culture condition:D-mandelate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000324
name: culture condition:D-arabinose-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000325
name: culture condition:D-galactose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000326
name: culture condition:D-lyxose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000327
name: culture condition:D-mannose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000328
name: culture condition:D-phenylglycine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000329
name: culture condition:D-ribose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000330
name: culture condition:D-ribose-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000331
name: L-929 cell
namespace: BrendaTissueOBO
def: "Mouse connective tissue fibroblast, established from the normal subcutaneous areolar and adipose tissue of a male C3H/An mouse; used as target in TNF detection assays." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "L929 cell" RELATED []
synonym: "NCTC clone 929" RELATED []
is_a: BTO:0000453 ! fibroblast cell line

[Term]
id: BTO:0000332
name: culture condition:dark-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000333
name: renal corpuscle
namespace: BrendaTissueOBO
def: "A mass of arterial capillaries enveloped in a capsule and attached to a tubule in the kidney." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "Malphigian corpuscle" RELATED []
relationship: part_of BTO:0000924 ! nephron

[Term]
id: BTO:0000334
name: decidua parietalis
namespace: BrendaTissueOBO
def: "The part of the decidua in the pregnant human female lining the uterus . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "decidua vera" RELATED []
relationship: part_of BTO:0001360 ! decidua

[Term]
id: BTO:0000335
name: deciduoma cell
namespace: BrendaTissueOBO
def: "1: A cell of a mass of tissue formed in the uterus following pregnancy that contains remnants of chorionic or decidual tissue.\n2: A cell of decidual tissue induced in the uterus (as by trauma) in the absence of pregnancy." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: DRV BTO:0001360 ! decidua

[Term]
id: BTO:0000336
name: caput epididymis
namespace: BrendaTissueOBO
def: "The head of the epididymis." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000408 ! epididymis

[Term]
id: BTO:0000337
name: dental follicle
namespace: BrendaTissueOBO
def: "The structure within the developing alveolar bone of the jaws enclosing the tooth germ. " [Dorlands Medical Dictionary:MerckSource]
synonym: "tooth follicle" RELATED []
is_a: BTO:0001511 ! tooth germ
relationship: REL BTO:0001090 ! mouth

[Term]
id: BTO:0000338
name: dental plaque
namespace: BrendaTissueOBO
def: "A soft, thin film of food debris, mucin, and dead epithelial cells deposited on the teeth, providing the medium for the growth of various bacteria. The main inorganic components are calcium and phosphorus, with small amounts of magnesium, potassium, and sodium; the organic matrix consists of polysaccharides, proteins, carbohydrates, lipids, and other components. Plaque plays an important etiologic role in the development of dental caries and periodontal and gingival diseases and provides the base for the development of materia alba; calcified plaque forms dental calculus." [Dorlands Medical Dictionary:MerckSource]
synonym: "bacterial plaque" RELATED []
relationship: REL BTO:0000397 ! tooth

[Term]
id: BTO:0000339
name: dental pulp
namespace: BrendaTissueOBO
def: "The soft sensitive tissue that fills the central cavity of a tooth." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=dental+pulp]
synonym: "dental pulp cell" RELATED []
relationship: part_of BTO:0000397 ! tooth

[Term]
id: BTO:0000340
name: culture condition:deoxyribonucleoside-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000341
name: diaphragm
namespace: BrendaTissueOBO
def: "The thin muscle below the lungs and heart that separates the chest from the abdomen." [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "diaphragm muscle" RELATED []
is_a: BTO:0000508 ! thorax muscle
relationship: part_of BTO:0000088 ! cardiovascular system

[Term]
id: BTO:0000342
name: diencephalon
namespace: BrendaTissueOBO
def: "The posterior subdivision of the forebrain." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=diencephalon]
synonym: "betweenbrain" RELATED []
synonym: "interbrain" RELATED []
relationship: part_of BTO:0000478 ! forebrain

[Term]
id: BTO:0000343
name: renal tubule
namespace: BrendaTissueOBO
def: "One of the minute, reabsorptive, secretory, and collecting canals, made up of basement membrane lined with epithelium, that form the substance of the kidneys." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000924 ! nephron

[Term]
id: BTO:0000344
name: stratum corneum
namespace: BrendaTissueOBO
def: "The horny outer layer of the epidermis, consisting mainly of dead or peeling cells." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "horny layer" RELATED []
relationship: part_of BTO:0000404 ! epidermis

[Term]
id: BTO:0000345
name: digestive gland
namespace: BrendaTissueOBO
def: "A gland, such as the liver or pancreas, that secretes into the alimentary canal substances necessary for digestion." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0001488 ! endocrine gland

[Term]
id: BTO:0000346
name: digestive juice
namespace: BrendaTissueOBO
synonym: "digestive fluid" RELATED []
relationship: DRV BTO:0000345 ! digestive gland

[Term]
id: BTO:0000347
name: reticulum
namespace: BrendaTissueOBO
def: "The second compartment of the stomach of a ruminant in which folds of the mucous membrane form hexagonal cells." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=reticulum]
is_a: BTO:0000480 ! forestomach

[Term]
id: BTO:0000348
name: omasum
namespace: BrendaTissueOBO
def: "The third division of the stomach of a ruminant animal, located between the abomasum and the reticulum" [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000480 ! forestomach

[Term]
id: BTO:0000349
name: gut cavity
namespace: BrendaTissueOBO
relationship: part_of BTO:0000545 ! gut

[Term]
id: BTO:0000350
name: culture condition:dimethylamine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000351
name: disc
namespace: BrendaTissueOBO
def: "The central part of the flower head of a typical composite made up of closely packed tubular flowers." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=disc]
synonym: "discus" RELATED []
synonym: "disk" RELATED []
relationship: part_of BTO:0000469 ! flower

[Term]
id: BTO:0000352
name: culture condition:DL-mandelate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000353
name: lung cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000763 ! lung

[Term]
id: BTO:0000354
name: DON cell
namespace: BrendaTissueOBO
def: "Lung cell line, established from a 8-months-old male of Cricetulus griseus (hamster, Chinese)." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000353 ! lung cell line

[Term]
id: BTO:0000355
name: dormant eye
namespace: BrendaTissueOBO
def: "An undeveloped growth bud." [Gardening Glossary:http\://www.boldweb.com/greenweb/glossary.htm]
is_a: BTO:0000158 ! plant bud
relationship: part_of BTO:0000285 ! corm

[Term]
id: BTO:0000356
name: breast cancer cell line
namespace: BrendaTissueOBO
is_a: BTO:0000816 ! breast cell line
relationship: DRV BTO:0000150 ! breast cancer cell

[Term]
id: BTO:0000357
name: nectary
namespace: BrendaTissueOBO
def: "A plant gland that secretes nectar." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nectary]
relationship: part_of BTO:0000469 ! flower

[Term]
id: BTO:0000358
name: McA-RH7777 cell
namespace: BrendaTissueOBO
alt_id: BTO:0003305
def: "Liver, hepatoma; Morris hepatoma 7777 cell line, established from a rattus norvegicus female." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "McArdle-RH7777 cell" RELATED []
synonym: "McArdleRH7777 cell" RELATED []
synonym: "McARH7777 hepatoma cell" RELATED []
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000359
name: middle cervical ganglion
namespace: BrendaTissueOBO
def: "A variable ganglion, often fused with the vertebral ganglion, on the sympathetic trunk at about the level of the cricoid cartilage; its postganglionic fibers are distributed mainly to the heart, cervical region, and upper limb." [Dorlands Medical Dictionary:MerckSource]
synonym: "ganglion cervicale medium" RELATED []
is_a: BTO:0000113 ! cervical ganglion

[Term]
id: BTO:0000360
name: posterior spinal root
namespace: BrendaTissueOBO
def: "The sensory division of each spinal nerve, attached centrally to the spinal cord and joining peripherally with the anterior (motor) root to form the nerve before it emerges through the intervertebral foramen: each posterior root bears a spinal ganglion and conveys sensory fibers to the spinal cord. There are 31 anterior and 31 posterior nerve roots: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. " [Dorlands Medical Dictionary:MerckSource]
synonym: "dorsal root of spinal nerve" RELATED []
synonym: "posterior root of spinal nerve" RELATED []
synonym: "radix posterior nervi spinalis" RELATED []
synonym: "root dorsali nervi spinalis" RELATED []
synonym: "root sensoria nervi spinalis" RELATED []
synonym: "sensory root of spinal nerve" RELATED []
synonym: "sensory spinal root" RELATED []
relationship: part_of BTO:0000883 ! spinal root

[Term]
id: BTO:0000361
name: stratum granulosum
namespace: BrendaTissueOBO
def: "A layer of granular cells lying immediately above the stratum germinativum in most parts of the epidermis . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0000404 ! epidermis

[Term]
id: BTO:0000362
name: urinary bladder cancer cell
namespace: BrendaTissueOBO
def: "Cancer cell of the organ responsible for temporarily holding urine after it leaves the kidneys." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "bladder cancer cell" RELATED []
synonym: "bladder carcinoma cell" RELATED []
synonym: "bladder tumour cell" RELATED []
synonym: "urinary bladder carcinoma cell" RELATED []
relationship: DRV BTO:0001418 ! urinary bladder

[Term]
id: BTO:0000363
name: culture condition:dulcitol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000364
name: stratum lucidum
namespace: BrendaTissueOBO
def: "A thin somewhat translucent layer of cells lying superficial to the stratum granulosum and under the stratum corneum esp. in thickened parts of the epidermis . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0000404 ! epidermis

[Term]
id: BTO:0000365
name: duodenum
namespace: BrendaTissueOBO
def: "The first part of the small intestine extending from the pylorus to the jejunum." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=duodenum]
relationship: part_of BTO:0000651 ! small intestine

[Term]
id: BTO:0000366
name: duodenal juice
namespace: BrendaTissueOBO
synonym: "duodenal luminal fluid" RELATED []
relationship: DRV BTO:0000365 ! duodenum

[Term]
id: BTO:0000367
name: duodenal mucosa
namespace: BrendaTissueOBO
def: "The duodenal mucosa (and that of the rest of the intestines) is classified as simple columnar. The cells rest on a basal lamina, which you may be able to make out in this image as a bright line underneath the cells. They sit over the lamina propria, the loose collagenous CT, filled with cells, that constitutes the core of each villus." [Veterinary Histology:http\://education.vetmed.vt.edu/Curriculum/VM8054/Labs/Lab19/EXAMPLES/Exduomuc.htm]
synonym: "duodenum mucosa" RELATED []
is_a: BTO:0000642 ! intestinal mucosa
relationship: part_of BTO:0000365 ! duodenum

[Term]
id: BTO:0000368
name: ear
namespace: BrendaTissueOBO
def: "The organ of hearing." [Dorlands Medical Dictionary:MerckSource]
synonym: "auris" RELATED []
is_a: BTO:0000202 ! sense organ
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0000369
name: egg
namespace: BrendaTissueOBO
def: "The hard-shelled reproductive body produced by a bird and especially by the common domestic chicken; also: its contents used as food." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=egg]
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0000370
name: egg white
namespace: BrendaTissueOBO
def: "Eggs are composed of 56 to 61% egg white and 27 to 32% egg yolk. The egg white is approximately 87 to 89% water and 9 to 11% protein, whereas the egg yolk contains 50% water, 32 to 35% lipid, and 16% protein. The predominant protein in the egg white is ovalbumin, comprising 54% of the protein present. Other major proteins in the egg white are ovotransferrin (12%), ovomucoid (11%), ovomucin (3.5%), and lysozyme." [Database of Food Allergens in AgMoBiol (Lab of Agricultural Molecular Biology):http\://ambl.lsc.pku.edu.cn/yjwy/Allergens2.htm]
relationship: part_of BTO:0000369 ! egg

[Term]
id: BTO:0000371
name: egg yolk
namespace: BrendaTissueOBO
def: "The yellow spheroidal mass of stored food that forms the inner portion of the egg of a bird or reptile and is surrounded by the white." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=egg+yolk]
synonym: "yolk" RELATED []
relationship: part_of BTO:0000369 ! egg

[Term]
id: BTO:0000372
name: bone cancer cell
namespace: BrendaTissueOBO
def: "Cancer cell of the skeleton. Cancers that begin in bone are rare but it is not unusual for cancers to spread (metastasize) to bone from other parts of the body. This is not called bone cancer, but is named for the organ or tissue in which the cancer begins." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
relationship: DRV BTO:0000140 ! bone

[Term]
id: BTO:0000373
name: Ehrlich ascites carcinoma cell
namespace: BrendaTissueOBO
def: "Mouse cancer cell." [PMID:2791164]
synonym: "EAT cell" RELATED []
synonym: "Ehrlich ascites tumor cell" RELATED []
is_a: BTO:0000150 ! breast cancer cell

[Term]
id: BTO:0000374
name: bone cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000140 ! bone

[Term]
id: BTO:0000375
name: keratinocyte cell line
namespace: BrendaTissueOBO
synonym: "KC" RELATED []
relationship: DRV BTO:0000667 ! keratinocyte

[Term]
id: BTO:0000376
name: electric organ
namespace: BrendaTissueOBO
def: "A specialized tract of tissue (as in the electric eel) in which electricity is generated." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=electric+organ]
relationship: part_of BTO:0001348 ! tail

[Term]
id: BTO:0000377
name: elementary body
namespace: BrendaTissueOBO
def: "The infectious form of chlamydiaceae. Infection occurs when the small, rigid-walled extracellular form (elementary body) enters the cell and changes into a larger, thin-walled form (initial body) that divides by fission. The daughter cells thus formed reorganize and condense to become elementary bodies that then infect other cells. The organisms are parasites of humans and other vertebrates, capable of producing a variety of diseases. They have also been found in arthropods. The family contains the genus Chlamydia." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0000378
name: elytron
namespace: BrendaTissueOBO
def: "One of the anterior wings in beetles and some other insects that serve to protect the posterior pair of functional wings." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=elytron]
is_a: BTO:0001463 ! wing

[Term]
id: BTO:0000379
name: embryo
namespace: BrendaTissueOBO
def: "An animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems; especially: the developing human individual from the time of implantation to the end of the eighth week after conception." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=embryo]
is_a: BTO:0000174 ! embryonic structure

[Term]
id: BTO:0000380
name: embryonic axis
namespace: BrendaTissueOBO
def: "The main root/shoot body of a seedling." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0000387" RELATED []
relationship: part_of BTO:0001233 ! plant embryo

[Term]
id: BTO:0000381
name: embryonic blood
namespace: BrendaTissueOBO
is_a: BTO:0000089 ! blood
relationship: part_of BTO:0000379 ! embryo

[Term]
id: BTO:0000382
name: Kc cell
namespace: BrendaTissueOBO
def: "Drosophila embryo cell line. Morphology: Semi-Adherent." [European collection of cell cultures:ECACC]
is_a: BTO:0000669 ! embryonic cell line

[Term]
id: BTO:0000383
name: renal cell carcinoma cell line
namespace: BrendaTissueOBO
synonym: "hypernephroma cell line" RELATED []
synonym: "kidney adenocarcinoma cell line" RELATED []
synonym: "RCC cell line" RELATED []
synonym: "renal cell adenocarcinoma cell line" RELATED []
is_a: BTO:0003192 ! renal cancer cell line

[Term]
id: BTO:0000384
name: emulsin
namespace: BrendaTissueOBO
def: "The white milky pulp or extract of bitter almonds." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=emulsin]
is_a: BTO:0000659 ! juice
is_a: BTO:0001142 ! pulp

[Term]
id: BTO:0000385
name: bone cancer cell line
namespace: BrendaTissueOBO
is_a: BTO:0000374 ! bone cell line
relationship: DRV BTO:0000372 ! bone cancer cell

[Term]
id: BTO:0000386
name: culture condition:(NH4)2SO4-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000387
name: endocardium
namespace: BrendaTissueOBO
def: "A thin serous membrane lining the cavities of the heart." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=endocardium]
relationship: part_of BTO:0000562 ! heart

[Term]
id: BTO:0000388
name: endodermis
namespace: BrendaTissueOBO
def: "The innermost tissue of the cortex in many roots and stems." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=endodermis]
relationship: part_of BTO:0000713 ! leaf
relationship: part_of BTO:0001184 ! rind
relationship: part_of BTO:0001188 ! root

[Term]
id: BTO:0000389
name: mature ovarian follicle
namespace: BrendaTissueOBO
def: "A liquid-filled cavity in a mammalian ovary containing a mature egg before ovulation." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=graafian+follicle]
synonym: "antral follicle" RELATED []
synonym: "folliculi ovarici vesiculosi" RELATED []
synonym: "graafian follicle" RELATED []
synonym: "preovulatory follicle" RELATED []
synonym: "secondary ovarian follicle" RELATED []
synonym: "vesicular ovarian follicle" RELATED []
is_a: BTO:0000475 ! ovarian follicle

[Term]
id: BTO:0000390
name: endosperm
namespace: BrendaTissueOBO
def: "A triploid nutritive tissue resulting from the fusion of a haploid sperm nucleus with the two haploid polar nuclei in the ovule of angiosperms." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005361" RELATED []
relationship: part_of BTO:0001226 ! seed

[Term]
id: BTO:0000391
name: DLD-1 cell
namespace: BrendaTissueOBO
def: "Human colon adenocarcinoma established from a colorectal adenocarcinoma." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0001913 ! colonic adenocarcinoma cell line

[Term]
id: BTO:0000392
name: plasma cell
namespace: BrendaTissueOBO
def: "A terminally differentiated cell of the B lymphocyte lineage that produces antibodies; plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern." [Dorlands Medical Dictionary:MerckSource]
synonym: "plasmacyte" RELATED []
synonym: "plasmocyte" RELATED []
relationship: DRV BTO:0000776 ! B-lymphocyte
relationship: part_of BTO:0000141 ! bone marrow

[Term]
id: BTO:0000393
name: endothelium
namespace: BrendaTissueOBO
def: "An epithelium of mesodermal origin composed of a single layer of thin flattened cells that lines internal body cavities." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=endothelium]
is_a: BTO:0000416 ! epithelium

[Term]
id: BTO:0000394
name: aorta endothelium
namespace: BrendaTissueOBO
def: "Simple squamous epithelium which lines the lumen side of the blood vessel. " [Histology Laboratory Index://erl.pathology.iupui.edu/Histo/generator.cfm?UnlabeledImage=EPI_01U&Lab=Epithelium]
synonym: "aortic endothelium" RELATED []
is_a: BTO:0000393 ! endothelium
is_a: BTO:0001853 ! vascular endothelium
relationship: part_of BTO:0000135 ! aorta

[Term]
id: BTO:0000395
name: alveolar cell
namespace: BrendaTissueOBO
def: "Any cell of the walls of the pulmonary alveoli; the term is often limited to alveolar epithelial cells (type I and type II alveolar cells) and alveolar macrophages. " [Dorlands Medical Dictionary:MerckSource]
synonym: "pneumocyte" RELATED []
synonym: "pneumonocyte" RELATED []
relationship: part_of BTO:0002543 ! alveolar wall

[Term]
id: BTO:0000396
name: EAhy 926 cell
namespace: BrendaTissueOBO
def: "The EAhy 926 cell is a hybridoma line derived from human endothelium and A549/8 cells. They display stable endothelial characteristics and may provide an indication of how endothelial cells respond to photodynamic therapy." [The photodynamic response of an endothelial hybridoma cell line using zinc (II) tetrasubstituted phthalocyanines:Cruse-Sawyer \, J.E. \, Dixon \, B. \, Roberts \, D.J.H. \, Schofield \, J. \, Griffiths \, J. and Brown \, S.B. (1995) in '5th International Photodynamic Association Biennial Meeting' \, D.A. Cortese \, ed. Proc. SPIE \, 2371 \, 198-203.]
synonym: "EA.hy 926 cell" RELATED []
synonym: "EA.hy926 cell" RELATED []
synonym: "EAhy926 cell" RELATED []
is_a: BTO:0000762 ! lung cancer cell line
is_a: BTO:0001519 ! endothelial cell line

[Term]
id: BTO:0000397
name: tooth
namespace: BrendaTissueOBO
def: "1: One of the hard bony appendages that are borne on the jaws or in many of the lower vertebrates on other bones in the walls of the mouth or pharynx and serve especially for the prehension and mastication of food and as weapons of offense and defense.\n2: Any of various usually hard and sharp processes especially about the mouth of an invertebrate." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tooth]
relationship: part_of BTO:0001090 ! mouth

[Term]
id: BTO:0000398
name: enterocyte
namespace: BrendaTissueOBO
def: "Cell of the intestinal epithelium." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000781 ! intestinal epithelium

[Term]
id: BTO:0000399
name: eosinophil
namespace: BrendaTissueOBO
def: "A white blood cell or other granulocyte with cytoplasmic inclusions readily stained by eosin." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=eosinophil]
synonym: "eosinophil granulocyte" RELATED []
is_a: BTO:0000539 ! granulocyte

[Term]
id: BTO:0000400
name: sarcoma cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001207 ! sarcoma cell

[Term]
id: BTO:0000401
name: ependymal epithelium
namespace: BrendaTissueOBO
def: "Ependymal epithelium lining the ventricular cavities and canals of the CNS is simple, columnar or cuboidal." [West Virginia University \, Anatomy Department \, Beresford \, W.A. \, Histology Chapter 11 \, Central Nervous System:http\://wberesford.hsc.wvu.edu/histolch11.htm]
synonym: "ependyma" RELATED []
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0001442 ! brain ventricle

[Term]
id: BTO:0000402
name: epicotyl
namespace: BrendaTissueOBO
def: "Portion of the shoot of an angiosperm embryo or seedling above the cotyledons. " [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005383" RELATED []
relationship: part_of BTO:0001495 ! plumule

[Term]
id: BTO:0000403
name: mastocytoma cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000832 ! mastocytoma cell

[Term]
id: BTO:0000404
name: epidermis
namespace: BrendaTissueOBO
def: "The outer epithelial layer of the external integument of the animal body that is derived from the embryonic epiblast; specifically: the outer nonsensitive and nonvascular layer of the skin of a vertebrate that overlies the dermis." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=epidermis]
relationship: part_of BTO:0001253 ! skin

[Term]
id: BTO:0000405
name: penis
namespace: BrendaTissueOBO
def: "A male organ of copulation that in male mammals including humans usually functions as the channel by which urine leaves the body." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=penis]
is_a: BTO:0003097 ! external male genital organ
relationship: part_of BTO:0000082 ! male reproductive system

[Term]
id: BTO:0000406
name: L-428 cell
namespace: BrendaTissueOBO
def: "Human Hodgkin's lymphoma, established from the pleural effusion of a 37-year-old woman with Hodgkin's lymphoma (stage IVB, nodular sclerosis, refractory, terminal) in 1978." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "L428 cell" RELATED []
is_a: BTO:0000104 ! lymphoma cell line

[Term]
id: BTO:0000407
name: osteosarcoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000385 ! bone cancer cell line

[Term]
id: BTO:0000408
name: epididymis
namespace: BrendaTissueOBO
def: "A system of ductules emerging posteriorly from the testis that holds sperm during maturation and that forms a tangled mass before uniting into a single coiled duct which is continuous with the vas deferens." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=epididymis]
is_a: BTO:0003096 ! internal male genital organs
relationship: part_of BTO:0000082 ! male reproductive system

[Term]
id: BTO:0000409
name: epimastigote
namespace: BrendaTissueOBO
def: "Any of the bodies representing the morphologic (crithidial) stage in the life cycle of certain trypanosomatid protozoa resembling the typical adult form of members of the genus Crithidia, in which the kinetoplast and basal body are located anterior to the central vesicular nucleus of the slender elongate cell and the flagellum is attached to the body up to the anterior end by a short undulating membrane before becoming free-flowing." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000092 ! trypanosome

[Term]
id: BTO:0000410
name: immature ovarian follicle
namespace: BrendaTissueOBO
def: "Primary ovarian follicles: immature ovarian follicles, each comprising an immature ovum and the specialized epithelial cells (follicle cells) that surround it." [Dorlands Medical Dictionary:MerckSource]
synonym: "primary ovarian follicle" RELATED []
is_a: BTO:0000475 ! ovarian follicle

[Term]
id: BTO:0000411
name: cervical mucosa
namespace: BrendaTissueOBO
def: "Lining of the head of the uterus (cervix); contains large branched glands; does not undergo sloughing." [Review Glossary:http\://medinfo.ufl.edu/]
is_a: BTO:0000886 ! mucosa
relationship: part_of BTO:0001421 ! uterine cervix
relationship: part_of BTO:0001424 ! uterus

[Term]
id: BTO:0000412
name: epiphyseal growth plate
namespace: BrendaTissueOBO
def: "The disk or plate of cartilage interposed between the epiphysis and the shaft of the bone during the period of growth; by its growth the bone increases in length. " [Dorlands Medical Dictionary:MerckSource]
synonym: "cartilago epiphysialis" RELATED []
synonym: "epiphyseal cartilage" RELATED []
synonym: "epiphyseal disk" RELATED []
synonym: "epiphyseal growth disk" RELATED []
synonym: "growth plate" RELATED []
synonym: "physis" RELATED []
is_a: BTO:0000206 ! cartilage
relationship: part_of BTO:0000140 ! bone

[Term]
id: BTO:0000413
name: epiphysis
namespace: BrendaTissueOBO
def: "A part or process of a bone that ossifies separately and later becomes ankylosed to the main part of the bone; especially: an end of a long bone." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=epiphysis]
relationship: part_of BTO:0000140 ! bone

[Term]
id: BTO:0000414
name: epithelial cell
namespace: BrendaTissueOBO
def: "Cell that cover the surface of the body and line its cavities." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000416 ! epithelium

[Term]
id: BTO:0000415
name: epithelioma cell
namespace: BrendaTissueOBO
def: "A neoplasm cell of epithelial origin, ranging from benign (adenoma and papilloma) to malignant (carcinoma)." [Dorlands Medical Dictionary:MerckSource]
relationship: DRV BTO:0000414 ! epithelial cell

[Term]
id: BTO:0000416
name: epithelium
namespace: BrendaTissueOBO
def: "1: A membranous cellular tissue that covers a free surface or lines a tube or cavity of an animal body and serves especially to enclose and protect the other parts of the body, to produce secretions and excretions, and to function in assimilation.\n2: A usually thin layer of parenchyma that lines a cavity or tube of a plant." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=epithelium]
is_a: BTO:0000634 ! integument

[Term]
id: BTO:0000417
name: bile duct epithelium
namespace: BrendaTissueOBO
def: "The irregularly shaped proliferating bile ducts are lined by normal cuboidal epithelium." [eMedicine \, Nazer H. \, Congenital Hepatic Fibrosis:http\://www.emedicine.com/ped/topic459.htm]
is_a: BTO:0001513 ! biliary epithelium
relationship: part_of BTO:0000122 ! bile duct

[Term]
id: BTO:0000418
name: neostriatum
namespace: BrendaTissueOBO
def: "The neostriatum is a compound structure comprised of the putamen and caudate nucleus. In birds, it also includes the high vocal center; it has evolved into a structure nowadays called nidopallium." [Wikipedia:The Free Encyclopedia]
relationship: part_of BTO:0001311 ! corpus striatum

[Term]
id: BTO:0000419
name: respiratory epithelium
namespace: BrendaTissueOBO
def: "Epithelium of the respiratory portion of the bronchial tree." [Review Glossary:http\://medinfo.ufl.edu/]
synonym: "airway epithelial cell" RELATED []
synonym: "airway epithelium" RELATED []
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0000136 ! bronchoalveolar system

[Term]
id: BTO:0000420
name: neck
namespace: BrendaTissueOBO
def: "The part of an animal that connects the head with the body." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=neck]
relationship: part_of BTO:0001493 ! trunk

[Term]
id: BTO:0000421
name: connective tissue
namespace: BrendaTissueOBO
def: "The tissue which binds together and is the support of the various structures of the body. It is made up of fibroblasts, fibroglia, collagen fibrils, and elastic fibrils. It is derived from the mesoderm and in a broad sense includes the collagenous, elastic, mucous, reticular, osseous, and cartilaginous tissue. Some also include the blood in this group of tissues. Connective tissue is classified according to concentration of fibers as loose (areolar) and dense, the latter having more abundant fibers than the former." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000422
name: vaginal epithelium
namespace: BrendaTissueOBO
def: "Vaginal epithelium is stratified squamous epithelium having a thickness of 15-200 microns." [Dictionary of Sexuality:http\://www.sex-dictionary.info/alphabet/vagina.htm]
synonym: "epithelium, vaginal" RELATED []
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0000243 ! vagina

[Term]
id: BTO:0000423
name: epitrochlearis
namespace: BrendaTissueOBO
def: "Pertaining to muscles associated with the humeral epichondyle." [Illustrated Encyclopedia of Human Anatomic Variation:Part I Muscular System http\://www.vh.org/adult/provider/anatomy/AnatomicVariants/MuscularSystem/Terminology.html]
is_a: BTO:0000479 ! forelimb muscle

[Term]
id: BTO:0000424
name: erythrocyte
namespace: BrendaTissueOBO
def: "Any of the hemoglobin-containing cells that carry oxygen to the tissues and are responsible for the red color of vertebrate blood." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=erythrocyte]
synonym: "red blood cell" RELATED []
synonym: "red blood corpuscle" RELATED []
is_a: BTO:0000574 ! hematopoietic cell
relationship: DRV BTO:0001571 ! erythroblast
relationship: DRV BTO:0002731 ! erythroid cell

[Term]
id: BTO:0000425
name: erythrocytic stage
namespace: BrendaTissueOBO
def: "Merozoites from the liver infect red blood cells and replicate asexually through schizogony. This is the erythrocytic stage." [LifeCycle&Pathology of Plasmodium species:http\://www.msu.edu/course/zol/316/psppblood.htm]
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0000426
name: erythroleukemia cell
namespace: BrendaTissueOBO
def: "Cancer cell of the blood-forming tissues in which large numbers of immature, abnormal red blood cells are found in the blood and bone marrow. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
is_a: BTO:0000583 ! bone marrow cancer cell
is_a: BTO:0001271 ! leukemia cell

[Term]
id: BTO:0000427
name: pituitary gland cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001073 ! hypophysis

[Term]
id: BTO:0000428
name: culture condition:ethanol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000429
name: H69AR cell
namespace: BrendaTissueOBO
def: "Multidrug-resistant cell line, variant of H69." [HyperCLDB:http\://www.biotech.ist.unige.it/]
relationship: DRV BTO:0000679 ! H69 cell

[Term]
id: BTO:0000430
name: EUE cell
namespace: BrendaTissueOBO
def: "Human embryonic epithelial cell line." [PMID:9691432]
is_a: BTO:0000669 ! embryonic cell line
is_a: BTO:0001120 ! epithelial cell line

[Term]
id: BTO:0000431
name: excretory gland
namespace: BrendaTissueOBO
def: "A gland that discharges its secretion through a duct opening on an internal or external surface of the body, as a lacrimal gland." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000522 ! gland

[Term]
id: BTO:0000432
name: corpus cardiacum
namespace: BrendaTissueOBO
def: "A pair of neurohemal organs located on the walls of the aorta just behind the brain. The corpora cardiaca release their store of PTTH only after they receive a signal from neurosecretory cells in the brain." [Insect Physiology \, The endocrine system:http\://www.cals.ncsu.edu/course/ent425/tutorial/endocrine.html]
synonym: "corpora cardiaca" RELATED []
is_a: BTO:0001488 ! endocrine gland
is_a: BTO:0001803 ! retrocerebral complex

[Term]
id: BTO:0000433
name: exocrine acinar cell
namespace: BrendaTissueOBO
relationship: part_of BTO:0000765 ! exocrine gland

[Term]
id: BTO:0000434
name: exocrine pancreas
namespace: BrendaTissueOBO
def: "That part of the pancreas that acts as an exocrine gland, consisting of the pancreatic acini, which produce pancreatic juice and secrete it into the duodenum to aid in protein digestion." [Dorlands Medical Dictionary:MerckSource]
synonym: "exocrine part of pancreas" RELATED []
relationship: part_of BTO:0000988 ! pancreas

[Term]
id: BTO:0000435
name: stratum spinosum
namespace: BrendaTissueOBO
def: "The layers of prickle cells over the layer of the stratum germinativum capable of undergoing mitosis." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "prickle cell layer" RELATED []
relationship: part_of BTO:0000404 ! epidermis

[Term]
id: BTO:0000436
name: extensor digitorum longus
namespace: BrendaTissueOBO
def: "A pennate muscle on the lateral part of the front of the leg that extends the four small toes and dorsally flexes and pronates." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000151 ! extensor
relationship: part_of BTO:0000476 ! foot

[Term]
id: BTO:0000437
name: culture condition:glycerol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000438
name: stratum germinativum
namespace: BrendaTissueOBO
def: "The innermost layer of the epidermis consisting of a single row of columnar or cuboidal epithelial cells that continually divide and replace the rest of the epidermis as it wears away." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "Malpighian layer" RELATED []
relationship: part_of BTO:0000404 ! epidermis

[Term]
id: BTO:0000439
name: eye
namespace: BrendaTissueOBO
def: "An organ of sight; especially: a nearly spherical hollow organ that is lined with a sensitive retina, is lodged in a bony orbit in the skull, is the vertebrate organ of sight, and is normally paired.\n2: All the visible structures within and surrounding the orbit and including eyelids, eyelashes, and eyebrows." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=eye]
is_a: BTO:0000202 ! sense organ
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0000440
name: feces
namespace: BrendaTissueOBO
def: "Waste matter discharged from the body; especially: waste (as feces) discharged from the alimentary canal." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=feces]
synonym: "excrement" RELATED []
synonym: "faeces" RELATED []
relationship: DRV BTO:0000058 ! alimentary canal

[Term]
id: BTO:0000441
name: adipose
namespace: BrendaTissueOBO
def: "Of or relating to animal fat; broadly: FAT." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=adipose]
synonym: "fat" RELATED []
relationship: part_of BTO:0000443 ! adipocyte

[Term]
id: BTO:0000442
name: fat body
namespace: BrendaTissueOBO
def: "A fatty tissue especially of nearly mature insect larvae that serves as a food reserve." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=fat+body]
is_a: BTO:0001487 ! adipose tissue

[Term]
id: BTO:0000443
name: adipocyte
namespace: BrendaTissueOBO
def: "One of the fat-laden cells making up adipose tissue." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=adipocyte]
synonym: "fat cell" RELATED []
synonym: "lipocyte" RELATED []
relationship: part_of BTO:0000156 ! brown adipose tissue
relationship: part_of BTO:0000444 ! fat pad
relationship: part_of BTO:0001456 ! white adipose tissue

[Term]
id: BTO:0000444
name: fat pad
namespace: BrendaTissueOBO
def: "An accumulation of adipose tissue (fat cells) enclosed in fibrous tissue." [The JKL Medical Dictionary:http\://www.jklcompany.com/f.html]
is_a: BTO:0001487 ! adipose tissue

[Term]
id: BTO:0000445
name: cerebral lobe
namespace: BrendaTissueOBO
def: "The well defined areas of the cerebral cortex, demarcated by fissures, sulci, and arbitrary lines, including the frontal, temporal, parietal, and occipital lobes." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000233 ! cerebral cortex

[Term]
id: BTO:0000446
name: FDCP-Mix cl.A4 cell
namespace: BrendaTissueOBO
def: "Mouse bone marrow cell line, established from the long-term bone marrow cultures of BDF1 mice; cells are mIL-3-dependent (FDCP means \"factor dependent cell-Paterson\" after the Paterson Institute, Manchester, UK); it is described that cells can be maintained in a primitive state or induced to differentiate." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000264 ! bone marrow cell line

[Term]
id: BTO:0000447
name: feather
namespace: BrendaTissueOBO
def: "Any of the light horny epidermal outgrowths that form the external covering of the body of birds and that consist of a shaft bearing on each side a series of barbs which bear barbules which in turn bear barbicels commonly ending in hooked hamuli and interlocking with the barbules of an adjacent barb to link the barbs into a continuous vane." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=feather]
relationship: part_of BTO:0000404 ! epidermis
relationship: part_of BTO:0001463 ! wing

[Term]
id: BTO:0000448
name: fetal serum
namespace: BrendaTissueOBO
is_a: BTO:0001239 ! serum
relationship: part_of BTO:0000449 ! fetus

[Term]
id: BTO:0000449
name: fetus
namespace: BrendaTissueOBO
def: "An unborn or unhatched vertebrate especially after attaining the basic structural plan of its kind; specifically: a developing human from usually three months after conception to birth." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=fetus]
is_a: BTO:0000174 ! embryonic structure

[Term]
id: BTO:0000450
name: fiber
namespace: BrendaTissueOBO
def: "An elongated tapering thick-walled plant cell void at maturity that imparts elasticity, flexibility, and tensile strength." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=fiber]
comment: American Cotton (Gossypium hirsutum).
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0000451
name: fibrillar flight muscle
namespace: BrendaTissueOBO
def: "Insect flight muscle responsible for indirect flight. A single nerve impulse results in many cycles of flight muscle contraction and relaxation. " [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
is_a: BTO:0000467 ! flight muscle

[Term]
id: BTO:0000452
name: fibroblast
namespace: BrendaTissueOBO
def: "A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=fibroblast]
is_a: BTO:0000421 ! connective tissue

[Term]
id: BTO:0000453
name: fibroblast cell line
namespace: BrendaTissueOBO
synonym: "FCL" RELATED []
relationship: DRV BTO:0000452 ! fibroblast

[Term]
id: BTO:0000454
name: 3T6-Swiss albino cell
namespace: BrendaTissueOBO
def: "The 3T6 cell line is a collagen and hyaluronic acid secreting line established by G. Todaro and H. Green in 1963 from disaggregated Swiss mouse embryos." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0001958 ! embryonic fibroblast cell line

[Term]
id: BTO:0000455
name: JTC-15 cell
namespace: BrendaTissueOBO
def: "Rat hepatoma, established in 1963 from the ascites of a rat with hepatoma induced with 4-dimethylaminoazobenzene." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000582 ! hepatoma ascites cell line

[Term]
id: BTO:0000456
name: plasmacytoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0001035 ! hematopoietic cell line
relationship: DRV BTO:0001087 ! plasmacytoma cell

[Term]
id: BTO:0000457
name: CHO-K1 cell
namespace: BrendaTissueOBO
def: "Chinese hamster ovary cells, subclone from parental CHO cell line that was initiated from an ovary biopsy of an adult Chinese hamster in 1957." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
relationship: DRV BTO:0000246 ! CHO cell

[Term]
id: BTO:0000458
name: WI-38 cell
namespace: BrendaTissueOBO
def: "Human embryonic lung fibroblast cell line.The WI-38 human diploid cell line was derived by Leonard Hayflick from normal embryonic (3 months gestation) lung tissue." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000161 ! lung fibroblast cell line
is_a: BTO:0001958 ! embryonic fibroblast cell line

[Term]
id: BTO:0000459
name: fibrosarcoma cell
namespace: BrendaTissueOBO
def: "Fibrosarcoma is a malignant tumour derived from connective tissue fibroblast." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0001207 ! sarcoma cell
is_a: BTO:0001622 ! fibroblastoma cell

[Term]
id: BTO:0000460
name: fibrosarcoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000400 ! sarcoma cell line
is_a: BTO:0000453 ! fibroblast cell line
relationship: DRV BTO:0000459 ! fibrosarcoma cell

[Term]
id: BTO:0000461
name: HSDM1C1 cell
namespace: BrendaTissueOBO
def: "Mouse Swiss Albino fibrosarcoma cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000460 ! fibrosarcoma cell line

[Term]
id: BTO:0000462
name: fiddlehead
namespace: BrendaTissueOBO
def: "The coiled young frond of any of various ferns, some of which are considered a delicacy when cooked." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "crosier" RELATED []
is_a: BTO:0000713 ! leaf

[Term]
id: BTO:0000463
name: filament
namespace: BrendaTissueOBO
def: "A chainlike series of cells, as in many algae;\nPart of the stamen in a flower that supports the anther." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html, The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0001064 ! phycobiont
relationship: part_of BTO:0001461 ! whole plant
relationship: part_of BTO:0001559 ! stamen

[Term]
id: BTO:0000464
name: flagellate
namespace: BrendaTissueOBO
def: "A flagellate protozoan or alga." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=flagellate]
is_a: BTO:0000720 ! plant form
is_a: BTO:0002503 ! protozoan

[Term]
id: BTO:0000465
name: flavedo
namespace: BrendaTissueOBO
def: "Oil exists in the yellow layer of the peel of the lemon which is known as the \"flavedo\". It is found in balloon-like cells called \"oil glands\"." [Mount Albert Research Centre \, Auckland:Lodge \, N. \, The Unique Character of New Zealand Lemon Oil and Other Innovative Opportunities from Citrus]
relationship: part_of BTO:0000733 ! exocarp

[Term]
id: BTO:0000466
name: flexor digitorum longus
namespace: BrendaTissueOBO
def: "A muscle of the tibial side of the leg that flexes the terminal phalanx of each of the four small toes . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000477 ! foot muscle
is_a: BTO:0000722 ! leg muscle
is_a: BTO:0001257 ! flexor

[Term]
id: BTO:0000467
name: flight muscle
namespace: BrendaTissueOBO
relationship: part_of BTO:0001266 ! invertebrate muscular system
relationship: part_of BTO:0001463 ! wing

[Term]
id: BTO:0000468
name: floret
namespace: BrendaTissueOBO
def: "1: A small or reduced flower, especially one of the grasses and composite plants, such as a daisy.\n2: Any of the tight, branched clusters of flower buds that together form a head of cauliflower or broccoli." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "GRO:0005733" RELATED []
is_a: BTO:0000469 ! flower

[Term]
id: BTO:0000469
name: flower
namespace: BrendaTissueOBO
def: "The reproductive structure of the anthophyta or angiosperms. " [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005367" RELATED []
relationship: part_of BTO:0000628 ! inflorescence

[Term]
id: BTO:0000470
name: flower bud
namespace: BrendaTissueOBO
def: "A bud that will develop into a flower." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000158 ! plant bud
relationship: part_of BTO:0000628 ! inflorescence

[Term]
id: BTO:0000471
name: culture condition:fluorene-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000472
name: FM3A cell
namespace: BrendaTissueOBO
def: "Mouse mammary carcinoma cell line." [European collection of cell cultures:ECACC]
is_a: BTO:0000356 ! breast cancer cell line

[Term]
id: BTO:0000473
name: fetal membrane
namespace: BrendaTissueOBO
def: "Any membrane that functions for the protection or nourishment of respiration or excretion of a developing fetus." [Real Dictionary.com:http\://www.realdictionary.com/f/dir/fetalmembrane.asp]
relationship: part_of BTO:0000449 ! fetus

[Term]
id: BTO:0000474
name: allantois
namespace: BrendaTissueOBO
def: "A vascular fetal membrane of reptiles, birds, and mammals that is formed as a pouch from the hindgut and that in placental mammals is intimately associated with the chorion in formation of the placenta." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=allantois]
is_a: BTO:0000473 ! fetal membrane

[Term]
id: BTO:0000475
name: ovarian follicle
namespace: BrendaTissueOBO
def: "A vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells.\nBut there are also insect ovarian follicle cells." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=follicle, PMID:10440860]
relationship: part_of BTO:0000975 ! ovary

[Term]
id: BTO:0000476
name: foot
namespace: BrendaTissueOBO
def: "1: The terminal part of the vertebrate leg upon which an individual stands.\n2: An invertebrate organ of locomotion or attachment; especially: a ventral muscular surface or process of a mollusk." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=foot]
is_a: BTO:0001492 ! limb
relationship: part_of BTO:0000721 ! leg

[Term]
id: BTO:0000477
name: foot muscle
namespace: BrendaTissueOBO
is_a: BTO:0000722 ! leg muscle

[Term]
id: BTO:0000478
name: forebrain
namespace: BrendaTissueOBO
def: "The anterior of the three primary divisions of the developing vertebrate brain or the corresponding part of the adult brain that includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and that especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=forebrain]
synonym: "prosencephalon" RELATED []
relationship: part_of BTO:0000142 ! brain

[Term]
id: BTO:0000479
name: forelimb muscle
namespace: BrendaTissueOBO
def: "A muscle of a limb  (as an arm, wing, fin, or leg) that is situated anteriorly." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=forelimb]
is_a: BTO:0001103 ! skeletal muscle

[Term]
id: BTO:0000480
name: forestomach
namespace: BrendaTissueOBO
def: "Any of the first three stomachs of a ruminant, i.e., the rumen, reticulum, or omasum." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0001307 ! stomach

[Term]
id: BTO:0000481
name: culture condition:formate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000482
name: renal distal tubule
namespace: BrendaTissueOBO
def: "A distal, convoluted part of the ascending limb of the renal tubule, extending from the distal straight tubule to the junctional (connecting) tubule." [Dorlands Medical Dictionary:MerckSource]
synonym: "distal convoluted tubule" RELATED []
synonym: "distal tubule" RELATED []
relationship: part_of BTO:0000343 ! renal tubule

[Term]
id: BTO:0000483
name: frond
namespace: BrendaTissueOBO
def: "A large leaf (especially of a palm or fern) usually with many divisions." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=frond]
is_a: BTO:0000713 ! leaf

[Term]
id: BTO:0000484
name: frontal lobe
namespace: BrendaTissueOBO
def: "Front part of the brain; involved in planning, organizing, problem solving, selective attention, personality and a variety of \"higher cognitive functions\" including behavior and emotions." [A Guide to Brain Anatomy:http\://www.waiting.com/brainanatomy.html]
synonym: "frontal cortex" RELATED []
relationship: part_of BTO:0000445 ! cerebral lobe

[Term]
id: BTO:0000485
name: culture condition:fructose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000486
name: fruit
namespace: BrendaTissueOBO
def: "The mature ovary or ovaries of a seed-bearing plant, together with accessory parts, containing the seeds and occurring in a wide variety of forms." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "GRO:0005250" RELATED []
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0000487
name: fruitbody
namespace: BrendaTissueOBO
def: "Any specialized structure which bears or contains sexually or asexually derived spores." [Microbial Structure Ontology Project:http\://www.geneontology.org/doc/microbial_structure_ontology/ont.defs.html]
synonym: "fruiting body" RELATED []
relationship: part_of BTO:0001494 ! fungus

[Term]
id: BTO:0000488
name: lower epidermis
namespace: BrendaTissueOBO
def: "The epidermal layer directed away or outwards from the axis." [Gramene DB:http\://dev.gramene.org/db/ontology/search/]
synonym: "abaxial epidermis" RELATED []
synonym: "GRO:0005682" RELATED []
is_a: BTO:0000718 ! leaf epidermis

[Term]
id: BTO:0000489
name: intestinal cancer cell
namespace: BrendaTissueOBO
is_a: BTO:0001533 ! gastrointestinal cancer cell
relationship: DRV BTO:0000648 ! intestine

[Term]
id: BTO:0000490
name: prostate gland ventral lobe
namespace: BrendaTissueOBO
relationship: part_of BTO:0000548 ! prostate gland lobe

[Term]
id: BTO:0000491
name: excretion
namespace: BrendaTissueOBO
def: "The matter, such as urine or sweat, that is excreted from the blood, tissues, or organs." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: DRV BTO:0000431 ! excretory gland

[Term]
id: BTO:0000492
name: MST cell
namespace: BrendaTissueOBO
def: "Furth murine mastocytoma cell line." [PMID:1454815]
is_a: BTO:0000403 ! mastocytoma cell line

[Term]
id: BTO:0000493
name: gall bladder
namespace: BrendaTissueOBO
def: "A small, pear-shaped muscular sac, located under the right lobe of the liver, in which bile secreted by the liver is stored until needed by the body for digestion." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000123 ! bladder

[Term]
id: BTO:0000494
name: germinal disc
namespace: BrendaTissueOBO
def: "A flattish area in a blastocyst in which the first traces of the embryo are seen, visible early in the second week in human development." [Dorlands Medical Dictionary:MerckSource]
synonym: "embryonic disc" RELATED []
synonym: "gastrodisk" RELATED []
synonym: "germ disc" RELATED []
is_a: BTO:0000514 ! germ
relationship: part_of BTO:0001099 ! blastocyst

[Term]
id: BTO:0000495
name: gametophyte
namespace: BrendaTissueOBO
def: "The individual or generation of a plant exhibiting alternation of generations that bears sex organs." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gametophyte]
is_a: BTO:0000720 ! plant form

[Term]
id: BTO:0000496
name: anterior lobe
namespace: BrendaTissueOBO
def: "The portion of the cerebellum lying in front of the primary fissure, comprising the lingula, central lobule, culmen, alae of central lobules, and quadrangular lobules." [Dorlands Medical Dictionary:MerckSource]
synonym: "cranial lobe" RELATED []
synonym: "rostral lobe" RELATED []
relationship: part_of BTO:0001073 ! hypophysis

[Term]
id: BTO:0000497
name: ganglion
namespace: BrendaTissueOBO
def: "A group of nerve cell bodies located outside the central nervous system. The term is occasionally applied to certain nuclear groups within the brain or spinal cord, such as the basal ganglia." [Dorlands Medical Dictionary:MerckMedicus]
synonym: "neural ganglion" RELATED []
relationship: part_of BTO:0001484 ! nervous system

[Term]
id: BTO:0000498
name: gastric cancer cell
namespace: BrendaTissueOBO
def: "Gastric cancer cell is cancer cell of the stomach." [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "stomach cancer cell" RELATED []
relationship: DRV BTO:0001307 ! stomach

[Term]
id: BTO:0000499
name: gastric corpus mucosa
namespace: BrendaTissueOBO
relationship: part_of BTO:0000505 ! gastric corpus
relationship: part_of BTO:0001308 ! gastric mucosa

[Term]
id: BTO:0000500
name: gastric epithelium
namespace: BrendaTissueOBO
def: "Epithelium of the stomach." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gastric]
synonym: "gastric epithelial cell" RELATED []
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0001307 ! stomach

[Term]
id: BTO:0000501
name: gastric juice
namespace: BrendaTissueOBO
def: "A thin watery acid digestive fluid secreted by glands in the mucous membrane of the stomach." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gastric+juice]
synonym: "succus gastricus" RELATED []
is_a: BTO:0000346 ! digestive juice
relationship: DRV BTO:0000503 ! gastric gland

[Term]
id: BTO:0000502
name: gastric fundus
namespace: BrendaTissueOBO
def: "That part of the stomach to the left and above the level of the entrance of the esophagus." [Dorlands Medical Dictionary:MerckSource]
synonym: "fundus gastricus" RELATED []
synonym: "fundus of stomach" RELATED []
synonym: "fundus ventricularis" RELATED []
synonym: "fundus ventriculi" RELATED []
relationship: part_of BTO:0001307 ! stomach

[Term]
id: BTO:0000503
name: gastric gland
namespace: BrendaTissueOBO
def: "Any of various glands in the walls of the stomach that secrete gastric juice." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gastric+gland]
relationship: part_of BTO:0001308 ! gastric mucosa

[Term]
id: BTO:0000504
name: pancreatic juice
namespace: BrendaTissueOBO
def: "The liquid secretion of the exocrine pancreas, which is discharged into the duodenum." [Dorlands Medical Dictionary:MerckSource]
synonym: "succus pancreaticus" RELATED []
is_a: BTO:0000346 ! digestive juice
relationship: DRV BTO:0000028 ! pancreatic acinar cell

[Term]
id: BTO:0000505
name: gastric corpus
namespace: BrendaTissueOBO
def: "That part of the stomach between the fundus and the pyloric part." [Dorlands Medical Dictionary:MerckSource]
synonym: "corpus gastricum" RELATED []
synonym: "corpus ventriculare" RELATED []
synonym: "corpus ventriculi" RELATED []
synonym: "gastric body" RELATED []
synonym: "stomach body" RELATED []
relationship: part_of BTO:0001307 ! stomach

[Term]
id: BTO:0000506
name: gastrocnemius
namespace: BrendaTissueOBO
def: "The largest and most superficial muscle of the calf of the leg arising by two heads from the condyles of the femur and attaching to a tendon that becomes part of the Achilles tendon." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gastrocnemicus]
synonym: "gastrocnemius muscle" RELATED []
is_a: BTO:0000722 ! leg muscle
relationship: part_of BTO:0000721 ! leg

[Term]
id: BTO:0000507
name: foregut
namespace: BrendaTissueOBO
def: "1: The anterior part of the embryonic alimentary canal of a vertebrate from which the pharynx, lungs, esophagus, stomach, liver, pancreas, and duodenum develop. \n2: The first part of the alimentary canal of an arthropod or annelid, which includes the buccal cavity, esophagus, crop, and gizzard." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000545 ! gut

[Term]
id: BTO:0000508
name: thorax muscle
namespace: BrendaTissueOBO
is_a: BTO:0001103 ! skeletal muscle
relationship: part_of BTO:0001368 ! thorax

[Term]
id: BTO:0000509
name: gastrodermis
namespace: BrendaTissueOBO
def: "The tissue lining the gut cavity of an invertebrate, which is responsible for digestion and absorption." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000349 ! gut cavity

[Term]
id: BTO:0000510
name: hindgut
namespace: BrendaTissueOBO
def: "The caudal portion of the embryonic alimentary canal in vertebrates." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000545 ! gut

[Term]
id: BTO:0000511
name: gastrointestinal tract
namespace: BrendaTissueOBO
def: "The gastrointestinal tract includes both stomach and intestine." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gastrointestinal]
relationship: part_of BTO:0000058 ! alimentary canal

[Term]
id: BTO:0000512
name: genitalia
namespace: BrendaTissueOBO
def: "The external genital organs." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=genitalia]
relationship: part_of BTO:0000081 ! reproductive system

[Term]
id: BTO:0000513
name: culture condition:geranoic acid-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000514
name: germ
namespace: BrendaTissueOBO
def: "A small mass of living substance capable of developing into an organism or one of its parts." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=germ]
is_a: BTO:0000174 ! embryonic structure
is_a: BTO:0000720 ! plant form

[Term]
id: BTO:0000515
name: haustorium
namespace: BrendaTissueOBO
def: "A food-absorbing outgrowth of a plant organ (as a hypha or stem)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=haustorium]
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0000516
name: ghost
namespace: BrendaTissueOBO
def: "A red blood cell that has lost its hemoglobin." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ghost]
is_a: BTO:0000424 ! erythrocyte

[Term]
id: BTO:0000517
name: culture condition:5-methylcytosine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000518
name: gill
namespace: BrendaTissueOBO
def: "A paired respiratory organ in fishes consisting of gill filaments on the gill arch in the posterior portion of the head and usually providing the primary exchange of gases between the blood and the surrounding water." [Dictionary of Ichthyology:http\://www.briancoad.com/Dictionary/Introduction.htm]
synonym: "branchia" RELATED []
is_a: BTO:0000203 ! respiratory system

[Term]
id: BTO:0000519
name: gingiva
namespace: BrendaTissueOBO
def: "The tissue that surrounds the necks of teeth and covers the alveolar parts of the jaws; broadly: the alveolar portion of a jaw with its enveloping soft tissues." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gingiva]
synonym: "gum" RELATED []
relationship: part_of BTO:0001021 ! periodontium

[Term]
id: BTO:0000520
name: gizzard
namespace: BrendaTissueOBO
def: "1: The muscular enlargement of the alimentary canal of birds that has usually thick muscular walls and a tough horny lining for grinding the food and when the crop is present follows it and the proventriculus.\n2: A thickened part of the alimentary canal in some animals (as an insect or an earthworm) that is similar in function to the crop of a bird." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gizzard]
is_a: BTO:0002263 ! ventriculus
relationship: part_of BTO:0000058 ! alimentary canal

[Term]
id: BTO:0000521
name: gizzard smooth muscle
namespace: BrendaTissueOBO
is_a: BTO:0001260 ! smooth muscle
relationship: part_of BTO:0000520 ! gizzard

[Term]
id: BTO:0000522
name: gland
namespace: BrendaTissueOBO
def: "A cell, group of cells, or organ of endothelial origin that selectively removes materials from the blood, concentrates or alters them, and secretes them for further use in the body or for elimination from the body." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gland]
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000523
name: gleba
namespace: BrendaTissueOBO
def: "The fleshy, spore-bearing inner mass of a puffball." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000487 ! fruitbody

[Term]
id: BTO:0000524
name: glia
namespace: BrendaTissueOBO
alt_id: BTO:0000525
def: "MERGED DEFINITION:\nTARGET DEFINITION: The delicate network of branched cells and fibers that supports the tissue of the central nervous system.\n--------------------\nSOURCE DEFINITION: The cells of the supportive tissue of the central nervous system (neuroglia). These non-neural cells are of three kinds: astrocytes, oligodendrocytes (collectively termed macroglia) and microglia." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "glial cell" EXACT []
synonym: "neuroglia" RELATED []
synonym: "neuroglia cell" RELATED []
synonym: "neuroglial cell" RELATED []
relationship: part_of BTO:0000142 ! brain
relationship: part_of BTO:0001279 ! spinal cord

[Term]
id: BTO:0000526
name: glioma cell
namespace: BrendaTissueOBO
def: "A tumor cell originating in the neuroglia of the brain or spinal cord." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "neurogliocytoma cell" RELATED []
synonym: "neuroglioma cell" RELATED []
synonym: "neurospongioma cell" RELATED []
relationship: DRV BTO:0000524 ! glia

[Term]
id: BTO:0000527
name: glioblastoma cell
namespace: BrendaTissueOBO
def: "Glioblastoma is a general term for malignant forms of astrocytoma." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000100 ! astrocytoma cell

[Term]
id: BTO:0000528
name: JTC-27 cell
namespace: BrendaTissueOBO
def: "Rat hepatoma, established from the transplantable rat ascites hepatoma AH-601 induced by feeding with aminoazotoluene; the hepatoma was passaged by intraperitoneal transplantation though JAR-2 rats." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000582 ! hepatoma ascites cell line

[Term]
id: BTO:0000529
name: C6 cell
namespace: BrendaTissueOBO
def: "The glial cell strain, C6, was cloned from a rat glial tumor induced by N-nitrosomethylurea by Benda et al. after a series of alternate culture and animal passages. Tissue: brain; glial cell; glioma. Morphology: fibroblast." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "C6 glioma cell" RELATED []
is_a: BTO:0000711 ! glioma cell line

[Term]
id: BTO:0000530
name: renal glomerulus
namespace: BrendaTissueOBO
def: "Globular tufts of capillaries, one projecting into the expanded end or capsule of each of the uriniferous tubules, which together with its surrounding capsule (glomerular capsule) constitute the renal corpuscle." [Dorlands Medical Dictionary:MerckSource]
synonym: "glomerular tuft" RELATED []
synonym: "glomerulus" RELATED []
synonym: "malphigian glomerulus" RELATED []
relationship: part_of BTO:0000333 ! renal corpuscle

[Term]
id: BTO:0000531
name: gluteal muscle
namespace: BrendaTissueOBO
def: "Any one of three large skeletal muscles that form the buttock and move the thigh." [Webster's Revised Unabridged Dictionary:1913]
synonym: "gluteus" RELATED []
is_a: BTO:0001261 ! abdominal muscle
relationship: REL BTO:0001367 ! thigh muscle
relationship: REL BTO:0001376 ! thigh

[Term]
id: BTO:0000532
name: culture condition:glycine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000533
name: culture condition:dihydroxyacetone-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000534
name: gonad
namespace: BrendaTissueOBO
def: "A reproductive gland (as an ovary or testis) that produces gametes." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gonad]
is_a: BTO:0000080 ! male reproductive gland
is_a: BTO:0000254 ! female reproductive gland

[Term]
id: BTO:0000535
name: germ cell
namespace: BrendaTissueOBO
def: "1. A gamete (as an egg or sperm cell) or one of its antecedent cells. \n2. A mature male or female germ cell usually possessing a haploid chromosome set and capable of initiating formation of a new diploid individual by fusion with a gamete of the opposite sex." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=germ+cell]
synonym: "gamete" RELATED []
synonym: "germ cell" RELATED []
relationship: DRV BTO:0000996 ! gametocyte
relationship: part_of BTO:0000514 ! germ

[Term]
id: BTO:0000536
name: gracilis muscle
namespace: BrendaTissueOBO
def: "The Gracilis is the most superficial muscle on the medial side of the thigh. It is thin and flattened, broad above, narrow and tapering below. It arises by a thin aponeurosis from the anterior margins of the lower half of the symphysis pubis and the upper half of the pubic arch. The fibers run vertically downward, and end in a rounded tendon, which passes behind the medial condyle of the femur, curves around the medial condyle of the tibia, where it becomes flattened, and is inserted into the upper part of the medial surface of the body of the tibia, below the condyle." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "gracilis" RELATED []
is_a: BTO:0001367 ! thigh muscle
relationship: part_of BTO:0001376 ! thigh

[Term]
id: BTO:0000537
name: nectar
namespace: BrendaTissueOBO
def: "A sweet liquid that is secreted by the nectaries of a plant and is the chief raw material of honey." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nectar]
relationship: DRV BTO:0000357 ! nectary

[Term]
id: BTO:0000538
name: alveolar cell type II
namespace: BrendaTissueOBO
def: "Pleomorphic cells of the pulmonary alveolar epithelium that secrete surfactant and are distinguished by abundant cytoplasm containing numerous lipid-rich multilamellar bodies." [Dorlands Medical Dictionary:MerckSource]
synonym: "alveolar type II cell" RELATED []
synonym: "granular pneumonocytes" RELATED []
synonym: "great alveolar cell" RELATED []
synonym: "large alveolar cell" RELATED []
synonym: "T2 cell" RELATED []
is_a: BTO:0000395 ! alveolar cell

[Term]
id: BTO:0000539
name: granulocyte
namespace: BrendaTissueOBO
def: "A polymorphonuclear white blood cell with granule-containing cytoplasm." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=granulocyte]
is_a: BTO:0000751 ! leukocyte

[Term]
id: BTO:0000540
name: pollen mother cell
namespace: BrendaTissueOBO
def: "A diploid plant cell that forms four microspores by meiosis; the microspores give rise to pollen grains in seed plants." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "GRO:0005828" RELATED []
relationship: part_of BTO:0000079 ! anther

[Term]
id: BTO:0000541
name: prostate gland dorsolateral lobe
namespace: BrendaTissueOBO
relationship: part_of BTO:0000548 ! prostate gland lobe

[Term]
id: BTO:0000542
name: granulosa cell
namespace: BrendaTissueOBO
def: "One of the estrogen-secreting cells of the epithelial lining of a graafian follicle or its follicular precursor." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=granulosa+cell]
synonym: "ovarian granulosa cell" RELATED []
relationship: part_of BTO:0000389 ! mature ovarian follicle
relationship: part_of BTO:0000410 ! immature ovarian follicle

[Term]
id: BTO:0000543
name: ground meristem
namespace: BrendaTissueOBO
def: "The part of a primary apical meristem remaining after differentiation of protoderm and procambium." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ground+meristem]
synonym: "GRO:0005755" RELATED []
relationship: part_of BTO:0000034 ! apical meristem

[Term]
id: BTO:0000544
name: guard cell
namespace: BrendaTissueOBO
def: "One of the two crescent-shaped epidermal cells that border and open and close a plant stoma." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=guard+cell]
synonym: "GRO:0000293" RELATED []
relationship: part_of BTO:0000718 ! leaf epidermis

[Term]
id: BTO:0000545
name: gut
namespace: BrendaTissueOBO
def: "1: The alimentary canal or a portion thereof, especially the intestine or stomach. \n2: The embryonic digestive tube, consisting of the foregut, the midgut, and the hindgut." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000058 ! alimentary canal
relationship: part_of BTO:0000379 ! embryo

[Term]
id: BTO:0000546
name: gut mucosa
namespace: BrendaTissueOBO
is_a: BTO:0000886 ! mucosa
relationship: part_of BTO:0000349 ! gut cavity

[Term]
id: BTO:0000547
name: gut wall
namespace: BrendaTissueOBO
relationship: part_of BTO:0000545 ! gut

[Term]
id: BTO:0000548
name: prostate gland lobe
namespace: BrendaTissueOBO
def: "The prostate consists of a median lobe and two lateral lobes." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0001129 ! prostate gland

[Term]
id: BTO:0000549
name: culture condition:H2/CO2-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000550
name: H35 cell
namespace: BrendaTissueOBO
def: "Rat hepatoma cell line." [PMID:11513951]
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000551
name: lung cancer cell
namespace: BrendaTissueOBO
def: "Cancer cell of the major organ of respiration the lung." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "lung carcinoma cell" RELATED []
relationship: DRV BTO:0000763 ! lung

[Term]
id: BTO:0000552
name: HaCaT cell
namespace: BrendaTissueOBO
def: "HaCaT is a spontaneously immortalized human keratinocyte cell line." [PMID:11836560]
is_a: BTO:0000375 ! keratinocyte cell line

[Term]
id: BTO:0000553
name: peripheral blood
namespace: BrendaTissueOBO
def: "Blood circulating throughout the body. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
relationship: part_of BTO:0000089 ! blood

[Term]
id: BTO:0000554
name: hair follicle
namespace: BrendaTissueOBO
def: "The tubular epithelial sheath that surrounds the lower part of the hair shaft and encloses at the bottom a vascular papilla supplying the growing basal part of the hair with nourishment." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hair+follicle]
is_a: BTO:0001470 ! epidermal cell
relationship: REL BTO:0001501 ! hair

[Term]
id: BTO:0000555
name: hair root
namespace: BrendaTissueOBO
def: "The enlarged basal part of a hair within the skin." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0001501 ! hair

[Term]
id: BTO:0000556
name: germ layer
namespace: BrendaTissueOBO
def: "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
relationship: part_of BTO:0000379 ! embryo

[Term]
id: BTO:0000557
name: harderian gland
namespace: BrendaTissueOBO
def: "An accessory lacrimal gland on the inner side of the orbit in reptiles and birds but usually degenerate in mammals." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000044 ! tear gland

[Term]
id: BTO:0000558
name: hatching gland
namespace: BrendaTissueOBO
def: "A transversely oriented set of cells located deep to the enveloping layer on the pericardial membrane, especially prominent during pharyngula period because of the brightly refractile cytoplasmic granules (containing hatching enzymes) of the principal cells of the gland;The fish hatching gland is a unicellular holocrine gland. Although it has recently been found that the precursors or immature forms of the gland cells considerably migrate in the embryonic body during development (see later), the final location of the hatching gland cells in fish is generally restricted to anterior and/or dorsal regions of a well-grown prehatching embryo. In medaka, the final location is somewhat unique: The giant gland cells are mostly localized in the inner surface of the buccal (or pharyngeal) cavity. " [Fish Biol J Medaka:9 \, 5-15 \, 1997 \, Yamagami \, K. \, A Short History of the Hatching Enzyme Studies in Medaka, The Zebrafish Information Network \, Glossary:http\://zfin.org/zf_info/zfbook/stages/gloss.html]
is_a: BTO:0000254 ! female reproductive gland
relationship: part_of BTO:0000379 ! embryo
relationship: part_of BTO:0001049 ! pharynx

[Term]
id: BTO:0000559
name: hatching liquid
namespace: BrendaTissueOBO
relationship: DRV BTO:0000558 ! hatching gland

[Term]
id: BTO:0000560
name: haustorial mother cell
namespace: BrendaTissueOBO
def: "When the tip of the infection hypha contacts a host cell wall, a haustorial mother cell (HM) is formed from which the haustorium (H) invades the host cell." [PMID:12167330]
relationship: part_of BTO:0000515 ! haustorium

[Term]
id: BTO:0000561
name: posterior lobe
namespace: BrendaTissueOBO
def: "The portion of the cerebellum separated from the anterior lobe by the primary fissure and from the flocculonodular lobe by the dorsolateral fissure; it comprises the declive, folium vermis, tuber vermis, pyramid, uvula, simple lobule, inferior and superior semilunar lobules, and tonsils." [Dorlands Medical Dictionary:MerckSource]
synonym: "caudal lobe" RELATED []
synonym: "lobe caudalis cerebelli" RELATED []
synonym: "middle lobe" RELATED []
relationship: part_of BTO:0000937 ! neurohypophysis

[Term]
id: BTO:0000562
name: heart
namespace: BrendaTissueOBO
def: "1: A hollow muscular organ of vertebrate animals that by its rhythmic contraction acts as a force pump maintaining the circulation of the blood. \n2: A structure in an invertebrate animal functionally analogous to the vertebrate heart." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=heart]
relationship: part_of BTO:0000088 ! cardiovascular system

[Term]
id: BTO:0000563
name: culture condition:aerobically-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000564
name: heart valve
namespace: BrendaTissueOBO
def: "A structure especially in a vein or lymphatic that closes temporarily a passage or orifice or permits movement of fluid in one direction only." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=valve]
relationship: part_of BTO:0000562 ! heart

[Term]
id: BTO:0000565
name: HEL cell
namespace: BrendaTissueOBO
def: "Human erythroleukemia, established from the peripheral blood of a 30-year-old man with erythroleukemia (AML M6) in relapse (after treatment for Hodgkin's disease) in 1980; cells were described to be capable of spontaneous and induced globin synthesis." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000846 ! erythroleukemia cell line

[Term]
id: BTO:0000566
name: pancreatic islet cancer cell
namespace: BrendaTissueOBO
relationship: DRV BTO:0000991 ! pancreatic islet

[Term]
id: BTO:0000567
name: HeLa cell
namespace: BrendaTissueOBO
def: "Human cervix carcinoma established from the epitheloid cervix carcinoma of a 31-year-old black woman in 1951; later diagnosis changed to adenocarcinoma; first aneuploid, continuously cultured human cell line." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "HELA cell" RELATED []
is_a: BTO:0000167 ! adenocarcinoma cell line

[Term]
id: BTO:0000568
name: HeLa-S3 cell
namespace: BrendaTissueOBO
def: "Human cervix carcinoma cell line is a subclone of its parent HELA derived in 1955." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "HeLa S3 cell" RELATED []
relationship: DRV BTO:0000567 ! HeLa cell

[Term]
id: BTO:0000569
name: exoerythrocytic stage
namespace: BrendaTissueOBO
def: "The spozoites move to the liver, enter liver cells and replicate asexually through schizogony. This is the exoerythrocytic stage." [LifeCycle&Pathology of Plasmodium species:http\://www.msu.edu/course/zol/316/psppblood.htm]
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0000570
name: hematopoietic system
namespace: BrendaTissueOBO
def: "The tissues concerned in production of the blood, including the bone marrow, liver, lymph nodes, spleen, and thymus." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000571
name: hemocyte
namespace: BrendaTissueOBO
def: "A blood cell especially of an invertebrate animal." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hemocyte]
synonym: "haemocyte" RELATED []
is_a: BTO:0000574 ! hematopoietic cell

[Term]
id: BTO:0000572
name: hemolymph
namespace: BrendaTissueOBO
def: "The circulatory fluid of various invertebrate animals that is functionally comparable to the blood and lymph of vertebrates." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hemolymph]
relationship: part_of BTO:0000570 ! hematopoietic system

[Term]
id: BTO:0000573
name: artery
namespace: BrendaTissueOBO
def: "Any of the tubular branching muscular- and elastic-walled vessels that carry blood from the heart through the body." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=artery]
is_a: BTO:0001102 ! blood vessel

[Term]
id: BTO:0000574
name: hematopoietic cell
namespace: BrendaTissueOBO
def: "A blood cell." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hematopoietic]
synonym: "blood cell" RELATED []
synonym: "hemopoietic cell" RELATED []
relationship: part_of BTO:0000089 ! blood

[Term]
id: BTO:0000575
name: hepatocyte
namespace: BrendaTissueOBO
def: "A liver cell. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
relationship: part_of BTO:0000759 ! liver

[Term]
id: BTO:0000576
name: B-16 cell
namespace: BrendaTissueOBO
def: "Mouse melanoma tumor cell." [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "B16 cell" RELATED []
is_a: BTO:0000848 ! melanoma cell

[Term]
id: BTO:0000577
name: Morris hepatoma 3924A cell
namespace: BrendaTissueOBO
def: "Rat Morris hepatoma 3924A cell." [PMID:11895004]
synonym: "3924A cell" RELATED []
synonym: "MH-3924A cell" RELATED []
synonym: "MH3924A cell" RELATED []
is_a: BTO:0001080 ! Morris hepatoma cell

[Term]
id: BTO:0000578
name: hepatoma cell line
namespace: BrendaTissueOBO
synonym: "HCC cell line" RELATED []
synonym: "hepatocarcinoma cell line" RELATED []
synonym: "hepatocellular carcinoma cell line" RELATED []
relationship: DRV BTO:0000224 ! liver cell line
relationship: DRV BTO:0000608 ! hepatoma cell

[Term]
id: BTO:0000579
name: eye cancer cell
namespace: BrendaTissueOBO
def: "A cell of a cancerous growth in any part of the eye." [Access Med Health Information Library:http\://www.hendrickhealth.org/healthy/002065.htm]
relationship: DRV BTO:0000439 ! eye

[Term]
id: BTO:0000580
name: blood cancer cell
namespace: BrendaTissueOBO
def: "The major forms of blood cancer are lymphoma, leukemia and multiple myeloma. They affect the way a body makes blood and provides immunity from other diseases." [Aetna InteliHealth:http\://www.intelihealth.com/IH/ihtIH/WSIHW000/8096/8514.html]
relationship: DRV BTO:0000089 ! blood

[Term]
id: BTO:0000581
name: MOPC-315 cell
namespace: BrendaTissueOBO
def: "Mouse B lymphocyte; plasmacytoma; myeloma. MOPC 315 plasmacytoma  was induced with mineral oil in a BALB/c mouse. " [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "MOPC 315 cell" RELATED []
relationship: DRV BTO:0001087 ! plasmacytoma cell

[Term]
id: BTO:0000582
name: hepatoma ascites cell line
namespace: BrendaTissueOBO
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000583
name: bone marrow cancer cell
namespace: BrendaTissueOBO
relationship: DRV BTO:0000141 ! bone marrow

[Term]
id: BTO:0000584
name: pancreatic cancer cell
namespace: BrendaTissueOBO
def: "Pancreatic cancer is a disease in which malignant (cancer) cells are found in the tissues of the pancreas. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "exocrine cancer cell" RELATED []
synonym: "pancreatic adenocarcinoma cell" RELATED []
synonym: "pancreatic carcinoma cell" RELATED []
is_a: BTO:0000604 ! adenocarcinoma cell
relationship: DRV BTO:0000988 ! pancreas

[Term]
id: BTO:0000585
name: intraocular melanoma cell
namespace: BrendaTissueOBO
def: "Cancer cell of the part of the eye called the uvea, which is composed of the iris (the colored part of the eye), the ciliary body (a muscle in the eye), and the choroid (a layer of tissue in the back of the eye). It is a type of MELANOMA and a very rare cancer, but the most common form of EYE CANCER in adults. If melanoma starts in the iris, there may be a dark spot on the iris. A symptom of melanoma in the ciliary body or choroid may be blurry vision." [The Cancer Dictionary:http\://ihc.cancersource.com/Resources/glossary/]
synonym: "ocular melanoma cell" RELATED []
is_a: BTO:0000579 ! eye cancer cell
is_a: BTO:0000848 ! melanoma cell

[Term]
id: BTO:0000586
name: colonic cancer cell
namespace: BrendaTissueOBO
def: "A malignant tumour arising from the inner wall of the large intestine." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "carcinoma cell, colon" RELATED []
synonym: "colon cancer cell" RELATED []
synonym: "colon carcinoma cell" RELATED []
synonym: "colonic carcinoma cell" RELATED []
is_a: BTO:0001533 ! gastrointestinal cancer cell
relationship: DRV BTO:0000269 ! colon

[Term]
id: BTO:0000587
name: C 108 cell
namespace: BrendaTissueOBO
def: "Mouse, C57BL/6,Lewis lung carcinoma cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000181 ! Lewis lung carcinoma cell line

[Term]
id: BTO:0000588
name: LL/2 (LLC1) cell
namespace: BrendaTissueOBO
def: "Mouse C57BL Lewis lung carcinoma cell line." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "LL/2(LLC1) cell" RELATED []
synonym: "LLC1 cell" RELATED []
is_a: BTO:0000181 ! Lewis lung carcinoma cell line

[Term]
id: BTO:0000589
name: primary meristem
namespace: BrendaTissueOBO
def: "Meristem (as procambium) derived from the apical meristem." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=primary+meristem]
synonym: "GRO:0005613" RELATED []
relationship: DRV BTO:0000034 ! apical meristem

[Term]
id: BTO:0000590
name: Alzheimer specific cell type
namespace: BrendaTissueOBO
def: "Alzheimer is a disease marked by the loss of cognitive ability, generally over a period of 10 to 15 years, and associated with the development of abnormal tissues and protein deposits in the cerebral cortex." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: REL BTO:0000233 ! cerebral cortex

[Term]
id: BTO:0000591
name: N1-S1 cell
namespace: BrendaTissueOBO
def: "The N1-S1 cell line was established from a Novikoff hepatoma induced by feeding 4-dimethylaminoazobenzene to a male rat." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
comment: Novikoff hepatoma cell line.
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000592
name: adrenal gland cancer cell
namespace: BrendaTissueOBO
def: "Adrenal gland cancers are rare cancers occuring in the endocrine tissue of the adrenals. They are characterized by overproduction of adrenal gland hormones." [Gale Encyclopedia of Medicine:Published December \, 2002 by the Gale Group]
synonym: "adrenal gland tumor cell" RELATED []
relationship: DRV BTO:0000047 ! adrenal gland

[Term]
id: BTO:0000593
name: Yoshida AH-130 cell
namespace: BrendaTissueOBO
def: "Undifferentiated, fast growing rat ascites hepatoma cell line." [PMID:2852063]
synonym: "Yoshida AH130 cell" RELATED []
is_a: BTO:0001404 ! Yoshida ascites hepatoma cell line

[Term]
id: BTO:0000594
name: liver cancer cell
namespace: BrendaTissueOBO
def: "Malignant (cancer) cells are found in the tissues of the liver. " [Medical Encyclopedia:http\://www.nlm.nih.gov/medlineplus/encyclopedia.html]
relationship: DRV BTO:0000759 ! liver

[Term]
id: BTO:0000595
name: FDCP-1 cell
namespace: BrendaTissueOBO
def: "Mouse bone marrow cell line, established from the long-term bone marrow culture of B6D2F1 mice; cells are IL-3-dependent; their differentiation is blocked; this subclone is responsive to G-CSF." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000264 ! bone marrow cell line

[Term]
id: BTO:0000596
name: P-19 cell
namespace: BrendaTissueOBO
def: "Mouse embryonal carcinoma cell line, established from the teratocarcinoma induced in a C3H/He strain mouse." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "P19 cell" RELATED []
is_a: BTO:0000306 ! teratocarcinoma cell line
is_a: BTO:0001437 ! embryonic carcinoma cell line

[Term]
id: BTO:0000597
name: hepatopancreas
namespace: BrendaTissueOBO
def: "Digestive gland of crustaceans with functions approximately analogous to liver and pancreas of vertebrates - enzyme secretion, food absorption and storage." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "midgut gland" RELATED []
is_a: BTO:0000345 ! digestive gland
relationship: part_of BTO:0000863 ! midgut

[Term]
id: BTO:0000598
name: B5/589 cell
namespace: BrendaTissueOBO
def: "Human mammary epithelial cell line." [PMID:7680645]
is_a: BTO:0002768 ! mammary epithelial cell line

[Term]
id: BTO:0000599
name: Hep-G2 cell
namespace: BrendaTissueOBO
def: "Human hepatocellular carcinoma, established from the tumor tissue of a 15-year-old Argentine boy with hepatocellular carcinoma in 1975; cell line is patented; cells were described to not harbor a hepatitis B virus genome; cells reportedly produce a variety of proteins: alpha-fetoprotein, albumin, alpha2-macroglobulin, alpha1-antitrypsin, transferrin, alpha1-antichymotrypsin, haptoglobin, complement (C3, C4), C3 activator, fibrinogen, alpha1-acid glycoprotein, alpha2-HS glycoprotein, beta-lipoprotein, retinol binding protein." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "HepG2 cell" RELATED []
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000600
name: heterocyst
namespace: BrendaTissueOBO
def: "A large transparent thick-walled cell that is found in the filaments of some blue-green algae and is the site of nitrogen fixation." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=heterocyst]
relationship: part_of BTO:0001064 ! phycobiont

[Term]
id: BTO:0000601
name: hippocampus
namespace: BrendaTissueOBO
def: "A curved elongated ridge that extends over the floor of the descending horn of each lateral ventricle of the brain and consists of gray matter covered on the ventricular surface with white matter;\nThe hippocampus is a part of the temporal lobe, which has a well established role in learning, memory and emotion." [A Digital Atlas of Neurochemical Anatomy in the Hippocampus:http\://www.isbe.man.ac.uk/research/Hippocampus/dp.html, From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hippocampus]
relationship: part_of BTO:0000928 ! limbic system
relationship: part_of BTO:0001355 ! temporal lobe

[Term]
id: BTO:0000602
name: histiocyte
namespace: BrendaTissueOBO
def: "A nonmotile macrophage of extravascular tissues and especially connective tissue." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=histiocyte]
synonym: "tissue macrophage" RELATED []
is_a: BTO:0000801 ! macrophage

[Term]
id: BTO:0000603
name: pre-B acute lymphoblastic leukemia cell line
namespace: BrendaTissueOBO
alt_id: BTO:0001554
synonym: "pre-B leukemia cell line" RELATED []
is_a: BTO:0000739 ! lymphoblastic leukemia cell line
is_a: BTO:0002144 ! acute lymphoblastic leukemia cell line
relationship: DRV BTO:0001094 ! pre-B acute lymphoblastic leukemia cell

[Term]
id: BTO:0000604
name: adenocarcinoma cell
namespace: BrendaTissueOBO
def: "A cell of a cancer that begins in cells that line certain internal organs and that have glandular (secretory) properties. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
is_a: BTO:0000176 ! carcinoma cell

[Term]
id: BTO:0000605
name: honey
namespace: BrendaTissueOBO
def: "A sweet viscid material elaborated out of the nectar of flowers in the honey sac of various bees." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=honey]
relationship: DRV BTO:0000537 ! nectar

[Term]
id: BTO:0000606
name: LK63 cell
namespace: BrendaTissueOBO
def: "Pre-B-cell acute lymphoblastic leukemia cell line." [PMID:1737782]
is_a: BTO:0000603 ! pre-B acute lymphoblastic leukemia cell line

[Term]
id: BTO:0000607
name: HTC cell
namespace: BrendaTissueOBO
def: "Rat hepatoma cell line. Derived from a rat ascites tumour, which in turn was derived from a solid hepatoma induced in male Buffalo rats by feeding them 0.04% N,N'-2,7fluorenyle-bis-2,2,2-trifluoroacetamide for 12.4 months." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000582 ! hepatoma ascites cell line

[Term]
id: BTO:0000608
name: hepatoma cell
namespace: BrendaTissueOBO
def: "Primary carcinoma of the liver cells. It ranges from a well-differentiated tumour difficult to distinguish from normal hepatocytes to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic or may form giant cells. Several classification schemes have been suggested. Hepatocellular carcinoma is very rare in the united states and western europe, but it is one of the most common cancers in eastern asia and sub-saharan africa. The cases are preponderantly male and, racially, whites have the lowest rates. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "HCC cell" RELATED []
synonym: "hepatocarcinoma cell" RELATED []
synonym: "hepatocellular carcinoma cell" RELATED []
synonym: "liver adenocarcinoma cell" RELATED []
is_a: BTO:0000594 ! liver cancer cell
is_a: BTO:0000604 ! adenocarcinoma cell

[Term]
id: BTO:0000609
name: husk
namespace: BrendaTissueOBO
def: "A usually dry or membranous outer covering (as a pod or hull or one composed of bracts) of various seeds and fruits." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=husk]
relationship: part_of BTO:0000486 ! fruit
relationship: part_of BTO:0001226 ! seed

[Term]
id: BTO:0000610
name: hybridoma cell
namespace: BrendaTissueOBO
def: "A cell hybrid in which a tumour cell forms one of the original source cells. In practice, confined to hybrids between T- or B-lymphocytes and appropriate myeloma cell lines." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: DRV BTO:0000776 ! B-lymphocyte
relationship: DRV BTO:0000782 ! T-lymphocyte

[Term]
id: BTO:0000611
name: culture condition:hydroxyproline-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000612
name: hypha
namespace: BrendaTissueOBO
def: "1: One of the filaments or threads composing the mycelium of a fungus.  \n2: Branching filamentous outgrowths produced by certain bacteria (e.g., Actinomyces, Hyphomicrobium), sometimes forming a mycelium." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0001436 ! mycelium

[Term]
id: BTO:0000613
name: hypocotyl
namespace: BrendaTissueOBO
def: "The part of the axis of a plant embryo or seedling below the cotyledon." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hypocotyl]
synonym: "GRO:0005342" RELATED []
relationship: part_of BTO:0001228 ! seedling
relationship: part_of BTO:0001233 ! plant embryo

[Term]
id: BTO:0000614
name: hypothalamus
namespace: BrendaTissueOBO
def: "A basal part of the diencephalon that lies beneath the thalamus on each side, forms the floor of the third ventricle, and includes vital autonomic regulatory centers.\nThe ventral part of the diencephalon that forms the floor and part of the lateral wall of the third ventricle. Anatomically, it includes the preoptic area, optic tract, optic chiasm, mammillary bodies, tuber cinereum, infundibulum, and neurohypophysis, but for physiological purposes the neurohypophysis is considered a distinct structure. The hypothalamus may be divided into five regions or areas (area hypothalamica rostralis, area hypothalamica dorsalis, area hypothalamica intermedia, area hypothalamica lateralis and area hypothalamica posterior) or into three longitudinal zones (periventricular zone, medial zone, and lateral zone). The hypothalamic nuclei constitute that part of the corticodiencephalic mechanism that activates, controls and integrates the peripheral autonomic mechanisms, endocrine activity, and many somatic functions, e.g., a general regulation of water balance, body temperature, sleep, and food intake, and the development of secondary sex characteristics. The hypothalamus secretes vasopressin and oxytocin, which are stored in the pituitary, as well as many releasing factors (hypophysiotropic hormones), by means of which it exerts control over functions of the adenohypophysis." [Dorlands Medical Dictionary:MerckSource, From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hypothalamus]
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0000342 ! diencephalon
relationship: part_of BTO:0000928 ! limbic system

[Term]
id: BTO:0000615
name: corpus callosum
namespace: BrendaTissueOBO
def: "The great band of commissural fibers uniting the cerebral hemispheres of higher mammals including humans." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=corpus+callosum]
relationship: part_of BTO:0000231 ! cerebral hemisphere

[Term]
id: BTO:0000616
name: I-cell
namespace: BrendaTissueOBO
def: "An abnormal fibroblast containing a large number of dark inclusions that fill the central part of the cytoplasm except for the juxtanuclear zone; seen in mucolipidosis II." [Dorlands Medical Dictionary:MerckSource]
relationship: DRV BTO:0000452 ! fibroblast

[Term]
id: BTO:0000617
name: ileal carcinoid cell
namespace: BrendaTissueOBO
synonym: "ileal tumor cell" RELATED []
is_a: BTO:0000729 ! carcinoid cell
relationship: DRV BTO:0000620 ! ileum

[Term]
id: BTO:0000618
name: ileal lavage
namespace: BrendaTissueOBO
relationship: REL BTO:0000620 ! ileum

[Term]
id: BTO:0000619
name: ileal mucosa
namespace: BrendaTissueOBO
is_a: BTO:0000642 ! intestinal mucosa
relationship: part_of BTO:0000620 ! ileum

[Term]
id: BTO:0000620
name: ileum
namespace: BrendaTissueOBO
def: "The last division of the small intestine extending between the jejunum and large intestine." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ileum]
synonym: "intestinum ileum" RELATED []
relationship: part_of BTO:0000651 ! small intestine
relationship: part_of BTO:0002273 ! ileocecum

[Term]
id: BTO:0000621
name: iliopsoas muscle
namespace: BrendaTissueOBO
def: "Two muscles that lie together low down in the rear of the abdomen;\nA compound muscle, consisting of the iliacus musculus and psoas major musculus. " [Encyclopaedia Familyhealth:http\://www.tiscali.co.uk/reference/encyclopaedia/familyhealth/dict/pages/i/46.html, Medical Dictionary:http\://cancerweb.ncl.ac.uk/omd/]
is_a: BTO:0001261 ! abdominal muscle

[Term]
id: BTO:0000622
name: culture condition:cyclopentanol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000623
name: culture condition:2-butyne-1,4-diol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000624
name: culture condition:cyclohexane-1,2-diol-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000625
name: culture condition:D-xylose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000626
name: culture condition:DL-5-methyltryptophan-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000627
name: HIT-T15 cell
namespace: BrendaTissueOBO
def: "Pancreatic beta cell line." [PMID:11226251]
is_a: BTO:0000183 ! pancreatic cell line
is_a: BTO:0000716 ! pancreatic beta cell line

[Term]
id: BTO:0000628
name: inflorescence
namespace: BrendaTissueOBO
def: "A flower cluster with a definite arrangement." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005317" RELATED []
synonym: "panicle" RELATED []
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0000629
name: ink
namespace: BrendaTissueOBO
def: "The black protective secretion of a cephalopod;\nThe ink is composed mostly of melanin and has been used as the artists pigment, sepia." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ink, The Columbia Encyclopedia:Sixth Edition. 2001]
relationship: DRV BTO:0000273 ! ink gland

[Term]
id: BTO:0000630
name: inner ear
namespace: BrendaTissueOBO
def: "The essential organ of hearing and equilibrium that is located in the temporal bone, is innervated by the auditory nerve, and includes the vestibule, the semicircular canals, and the cochlea." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=inner+eat]
synonym: "auris interna" RELATED []
synonym: "internal ear" RELATED []
relationship: part_of BTO:0000368 ! ear

[Term]
id: BTO:0000631
name: culture condition:inositol-deficient-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000632
name: insulinoma cell
namespace: BrendaTissueOBO
def: "A cell of a usually benign tumor of the insulin-secreting cells of the pancreas. " [Medical Encyclopedia:http\://www.nlm.nih.gov/medlineplus/encyclopedia.html]
is_a: BTO:0000584 ! pancreatic cancer cell

[Term]
id: BTO:0000633
name: intestine-407 cell
namespace: BrendaTissueOBO
def: "Human Caucasian embryonic intestine, HeLa characteristics." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "INT 407 cell" RELATED []
synonym: "intestine 407 cell" RELATED []
is_a: BTO:0000003 ! intestinal cell line

[Term]
id: BTO:0000634
name: integument
namespace: BrendaTissueOBO
def: "Something that covers or encloses; especially: an enveloping layer (as a skin, membrane, or husk) of an organism or one of its parts." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=integument]
synonym: "tegument" RELATED []
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0000635
name: yellow bone marrow
namespace: BrendaTissueOBO
def: "Ordinary bone marrow of the kind in which the fat cells predominate." [Dorlands Medical Dictionary:MerckSource]
synonym: "fat marrow" RELATED []
synonym: "medulla ossium flava" RELATED []
synonym: "yellow marrow" RELATED []
is_a: BTO:0000141 ! bone marrow

[Term]
id: BTO:0000636
name: internode
namespace: BrendaTissueOBO
def: "Region on a stem between nodes." [:PAE Virtual Glossary]
synonym: "GRO:0005303" RELATED []
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0000637
name: interphotoreceptor matrix
namespace: BrendaTissueOBO
def: "The interphotoreceptor matrix is a mucopolysaccharide matrix surrounding the outer segments of the photoreceptors. This contributes to the adhesion of the retina to the retinal pigment epithelium (RPE)." [:ARMD, :eMedicine, :Lee, :P.J., Retinal Electronic Prosthesis and RPE Transplantation:http\://www.emedicine.com/oph/topic763.htm]
relationship: part_of BTO:0001175 ! retina

[Term]
id: BTO:0000638
name: interrenal cell
namespace: BrendaTissueOBO
def: "Interrenal cells in elasmobranchs and bony fishes represent the equivalent of the mammalian adrenal cortex. The interrenal cells' appearance varies greatly in response to stress and reproduction. These cells produce corticosteroids with cortisol being the most quantitatively important." [:University of Victoria, Advanced imaging laboratory:http\://web.uvic.ca/ail/examples.html]
relationship: part_of BTO:0000808 ! interrenal gland

[Term]
id: BTO:0000639
name: intersegmental muscle
namespace: BrendaTissueOBO
def: "The short intersegmental muscle is located between the prothorax and the mesothorax." [:1999, :93-103, :Evolution of the metathoracic tympanal ear and its mesothoracic homologue in the Macrolepidoptera (Insecta), :G.G.E.; Fullard, :J.H., :Yack J.E.; Scudder, Zoomorphology:119]
relationship: part_of BTO:0001266 ! invertebrate muscular system
relationship: part_of BTO:0001368 ! thorax

[Term]
id: BTO:0000640
name: intestinal gland
namespace: BrendaTissueOBO
def: "Any of the tubular glands of the intestinal mucous membrane." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "crypt of Lieberkühn" RELATED []
synonym: "gland of Lieberkühn" RELATED []
synonym: "Lieberkühn`s gland" RELATED []
relationship: part_of BTO:0000642 ! intestinal mucosa

[Term]
id: BTO:0000641
name: colon descendens
namespace: BrendaTissueOBO
def: "The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending colon lying in the left iliac fossa is sometimes called the iliac colon." [Dorlands Medical Dictionary:MerckSource]
synonym: "descending colon" RELATED []
relationship: part_of BTO:0000269 ! colon

[Term]
id: BTO:0000642
name: intestinal mucosa
namespace: BrendaTissueOBO
def: "The surface lining of the intestines where the cells absorb nutrients." [:International Foundation for Functional Gastrointestinal Disorders, Glossary of terms:http\://www.iffgd.org/GIDisorders/glossary.html]
is_a: BTO:0000886 ! mucosa
relationship: part_of BTO:0000648 ! intestine

[Term]
id: BTO:0000643
name: intestinal muscle
namespace: BrendaTissueOBO
synonym: "intestinal smooth muscle" RELATED []
is_a: BTO:0001260 ! smooth muscle
relationship: part_of BTO:0000648 ! intestine

[Term]
id: BTO:0000644
name: intestinal juice
namespace: BrendaTissueOBO
def: "A fluid that is secreted in small quantity in the small intestine, is highly variable in constitution, and contains esp. various enzymes (as erepsin, lipase, lactase, enterokinase, and amylase) and mucus." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "succus entericus" RELATED []
is_a: BTO:0000346 ! digestive juice
relationship: DRV BTO:0000640 ! intestinal gland
relationship: REL BTO:0000651 ! small intestine

[Term]
id: BTO:0000645
name: colon sigmoideum
namespace: BrendaTissueOBO
def: "The S-shaped part of the colon which lies in the pelvis, extending from the pelvic brim to the third segment of the sacrum, and continuous above with the descending (or iliac) colon and below with the rectum." [Dorlands Medical Dictionary:MerckSource]
synonym: "pelvic colon" RELATED []
synonym: "sigmoid colon" RELATED []
synonym: "sigmoid flexure" RELATED []
relationship: part_of BTO:0000269 ! colon

[Term]
id: BTO:0000646
name: left colon
namespace: BrendaTissueOBO
def: "The distal portion of the colon; it develops embryonically from the hindgut and functions in the storage and elimination of waste." [Dorlands Medical Dictionary:MerckSource]
synonym: "distal colon" RELATED []
relationship: DRV BTO:0000510 ! hindgut
relationship: part_of BTO:0000269 ! colon

[Term]
id: BTO:0000647
name: intestinal wall
namespace: BrendaTissueOBO
synonym: "bowel wall" RELATED []
synonym: "gut wall" RELATED []
relationship: part_of BTO:0000648 ! intestine

[Term]
id: BTO:0000648
name: intestine
namespace: BrendaTissueOBO
def: "The tubular part of the alimentary canal that extends from the stomach to the anus." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=intestine]
synonym: "bowel" RELATED []
synonym: "gut" RELATED []
relationship: part_of BTO:0000511 ! gastrointestinal tract

[Term]
id: BTO:0000649
name: right colon
namespace: BrendaTissueOBO
def: "The proximal portion of the colon, extending from the ileocecal valve usually to a point proximal to the left colic flexure; it develops embryonically from the terminal portion of the midgut and functions in absorption." [Dorlands Medical Dictionary:MerckSource]
synonym: "proximal colon" RELATED []
relationship: DRV BTO:0000863 ! midgut
relationship: part_of BTO:0000269 ! colon

[Term]
id: BTO:0000650
name: endocrine pancreas
namespace: BrendaTissueOBO
def: "That part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin, glucagon, somatostatin, and sometimes pancreatic polypeptide directly into the bloodstream." [Dorlands Medical Dictionary:MerckSource]
synonym: "endocrine part of pancreas" RELATED []
relationship: part_of BTO:0000988 ! pancreas

[Term]
id: BTO:0000651
name: small intestine
namespace: BrendaTissueOBO
def: "The part of the intestine that lies between the stomach and colon, consists of duodenum, jejunum, and ileum, secretes digestive enzymes, and is the chief site of the absorption of digested nutrients. The proximal portion of the intestine." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=small+intestine]
synonym: "intestinum tenue" RELATED []
relationship: part_of BTO:0000648 ! intestine

[Term]
id: BTO:0000652
name: culture condition:mannuronate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000653
name: iris
namespace: BrendaTissueOBO
def: "The circular pigmented membrane behind the cornea, perforated by the pupil; the most anterior portion of the vascular tunic of the eye, it is made up of a flat bar of circular muscular fibers surrounding the pupil, a thin layer of smooth muscle fibers by which the pupil is dilated, thus regulating the amount of light entering the eye, and posteriorly two layers of pigmented epithelial cells. " [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000439 ! eye

[Term]
id: BTO:0000654
name: ciliary muscle
namespace: BrendaTissueOBO
def: "One of the muscles that relax the zonules to enable the lens to change shape for focusing. The zonules are fibers that hold the lens suspended in position and enable it to change shape during accommodation." [Medical Dictionary:http\://www.medterms.com/]
synonym: "Bowman`s muscles" RELATED []
synonym: "musculus ciliarus" RELATED []
is_a: BTO:0000021 ! head muscle
relationship: part_of BTO:0000439 ! eye

[Term]
id: BTO:0000655
name: iris smooth muscle
namespace: BrendaTissueOBO
is_a: BTO:0001260 ! smooth muscle
relationship: part_of BTO:0000653 ! iris

[Term]
id: BTO:0000656
name: iris sphincter muscle
namespace: BrendaTissueOBO
def: "Circular fibers of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil." [Dorlands Medical Dictionary:MerckSource]
synonym: "musculus sphincter pupillae" RELATED []
synonym: "sphincter muscle of pupil" RELATED []
is_a: BTO:0000655 ! iris smooth muscle

[Term]
id: BTO:0000657
name: jejunum
namespace: BrendaTissueOBO
def: "The section of the small intestine that comprises the first two fifths beyond the duodenum and that is larger, thicker-walled, and more vascular and has more circular folds than the ileum." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=jejunum]
synonym: "intestinum jejunum" RELATED []
relationship: part_of BTO:0000651 ! small intestine

[Term]
id: BTO:0000658
name: uterine adenocarcinoma cell
namespace: BrendaTissueOBO
def: "The most common form of endometrial carcinoma, containing tumor cells differentiated into glandular tissue with little or no stroma." [Dorlands Medical Dictionary:MerckSource]
synonym: "endometrial adenocarcinoma cell" RELATED []
synonym: "endometrial carcinoma cell" RELATED []
synonym: "endometrioid adenocarcinoma cell" RELATED []
synonym: "uterine cancer cell" RELATED []
is_a: BTO:0000257 ! uterine cancer cell
is_a: BTO:0000604 ! adenocarcinoma cell

[Term]
id: BTO:0000659
name: juice
namespace: BrendaTissueOBO
def: "The extractable fluid contents of cells or tissues." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=juice]
relationship: part_of BTO:0000486 ! fruit

[Term]
id: BTO:0000660
name: mycelial cord
namespace: BrendaTissueOBO
def: "Multihyphal linear aggregate; linearly extending, loose agglomeration of hyphae; generally not hardened or melanized." [Concepts in Mycology:http\://facstaff.bloomu.edu/chamuris/text/glossary.html]
synonym: "FAO:0001006" RELATED []
is_a: BTO:0001436 ! mycelium

[Term]
id: BTO:0000661
name: JURKAT cell
namespace: BrendaTissueOBO
def: "Human T cell leukemia, established from the peripheral blood of a 14-year-old boy with acute lymphoblastic leukemia (ALL) at first relapse in 1976; often this cell line is called \"JM (JURKAT and JM are derived from the same patient and are sister clones), occasionally JM may be a subclone with somewhat divergent features." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "JM cell" RELATED []
is_a: BTO:0002144 ! acute lymphoblastic leukemia cell line
is_a: BTO:0002504 ! T-lymphoblastic leukemia cell line

[Term]
id: BTO:0000662
name: nasopharynx
namespace: BrendaTissueOBO
def: "The upper part of the throat behind the nose. An opening on each side of the nasopharynx leads into the ear. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
relationship: part_of BTO:0001049 ! pharynx

[Term]
id: BTO:0000663
name: juxtaglomerular tumor cell
namespace: BrendaTissueOBO
def: "A rare benign tumor cell of renal juxtaglomerular cells in young men, causing hyperreninemia." [Dorlands Medical Dictionary:MerckSource]
synonym: "juxtaglomerular cell tumor cell" RELATED []
synonym: "kidney hemangiopericytoma cell" RELATED []
is_a: BTO:0000680 ! kidney cancer cell

[Term]
id: BTO:0000664
name: K-562 cell
namespace: BrendaTissueOBO
def: "Human chronic myeloid leukemia in blast crisis established from the pleural effusion of a 53-year-old woman with chronic myeloid leukemia (CML) in blast crisis in 1970; cells can be used as highly sensitive targets in in-vitro natural killer assays; cells produce hemoglobin; cells carry  the Philadelphia chromosome with a b3-a2 fusion gene." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "K562 cell" RELATED []
synonym: "K562wt cell" RELATED []
is_a: BTO:0002580 ! chronic myeloid leukemia cell line

[Term]
id: BTO:0000665
name: KB cell
namespace: BrendaTissueOBO
def: "Human cervix carcinoma (derivative of HELA) originally described as \"epidermoid carcinoma established from the mouth of a Caucasian man in 1954\"; however, as shown by DSMZ DNA fingerprinting (see below) this cell line must be considered an HELA subclone." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
relationship: DRV BTO:0000567 ! HeLa cell

[Term]
id: BTO:0000666
name: LoVo cell
namespace: BrendaTissueOBO
def: "Human colon adenocarcinoma cell line, established from the metastatic nodule resected from a 56-year-old Caucasian man with colon adenocarcinoma in 1972." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "LOVO cell" RELATED []
is_a: BTO:0001913 ! colonic adenocarcinoma cell line

[Term]
id: BTO:0000667
name: keratinocyte
namespace: BrendaTissueOBO
def: "Skin cell, of the keratinized layer of epidermis: its characteristic intermediate filament protein is cytokeratin." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0001470 ! epidermal cell

[Term]
id: BTO:0000668
name: kernel
namespace: BrendaTissueOBO
def: "The inner softer part of a seed, fruit stone, or nut." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=kernel]
relationship: part_of BTO:0000486 ! fruit
relationship: part_of BTO:0001226 ! seed

[Term]
id: BTO:0000669
name: embryonic cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000379 ! embryo

[Term]
id: BTO:0000670
name: KG-1 cell
namespace: BrendaTissueOBO
def: "Human acute myeloid leukemia, established from the bone marrow of a 59-year-old man with erythroleukemia that developped into acute myeloid leukemia (AML) at relapse in 1977; cells were described to form colonies in soft-agar in response to colony-stimulating factor." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "KG1 cell" RELATED []
is_a: BTO:0001883 ! acute myeloid leukemia cell line

[Term]
id: BTO:0000671
name: kidney
namespace: BrendaTissueOBO
def: "1: One of a pair of vertebrate organs situated in the body cavity near the spinal column that excrete waste products of metabolism, in humans are bean-shaped organs about 4 1/2 inches (11 1/2 centimeters) long lying behind the peritoneum in a mass of fatty tissue, and consist chiefly of nephrons by which urine is secreted, collected, and discharged into a main cavity whence it is conveyed by the ureter to the bladder.\n2: Any of various excretory organs of invertebrate animals." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=kidney]
is_a: BTO:0000431 ! excretory gland
is_a: BTO:0001491 ! viscus
relationship: part_of BTO:0001244 ! urinary tract
relationship: part_of BTO:0003092 ! urinary system

[Term]
id: BTO:0000672
name: hindbrain
namespace: BrendaTissueOBO
def: "The posterior of the three primary divisions of the developing vertebrate brain or the corresponding part of the adult brain that includes the cerebellum, the medulla oblongata, and in mammals the pons and that controls autonomic functions and equilibrium." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hindbrain]
synonym: "rhombencephalon" RELATED []
relationship: part_of BTO:0000146 ! brain stem

[Term]
id: BTO:0000673
name: metencephalon
namespace: BrendaTissueOBO
def: "The anterior segment of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the cerebellum and pons." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=metencephalon]
relationship: part_of BTO:0000672 ! hindbrain

[Term]
id: BTO:0000674
name: BHK 165-23 cell
namespace: BrendaTissueOBO
def: "Baby hamster kidney cell line." [PMID:2903106]
synonym: "BHK 165-23 cell" RELATED []
is_a: BTO:0001131 ! BHK cell

[Term]
id: BTO:0000675
name: SW-620 cell
namespace: BrendaTissueOBO
def: "Human, Caucasian, colon, adenocarcinoma cell line; established from the tissue of a 51-year-old Caucasian male." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "SW620 cell" RELATED []
is_a: BTO:0001913 ! colonic adenocarcinoma cell line

[Term]
id: BTO:0000676
name: fibroadenoma cell
namespace: BrendaTissueOBO
def: "A cell of adenoma containing fibrous tissue." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000178 ! adenoma cell

[Term]
id: BTO:0000677
name: plant tumor tissue
namespace: BrendaTissueOBO
relationship: DRV BTO:0001461 ! whole plant

[Term]
id: BTO:0000678
name: G-402 cell
namespace: BrendaTissueOBO
def: "Human Caucasian renal leiomyoblastoma cell line, derived from a tumour of a 9-month-old female Caucasian. Highly transformed and grows in soft agar. " [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0003192 ! renal cancer cell line

[Term]
id: BTO:0000679
name: H69 cell
namespace: BrendaTissueOBO
def: "Human Caucasian lung small cell carcinoma cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000762 ! lung cancer cell line

[Term]
id: BTO:0000680
name: kidney cancer cell
namespace: BrendaTissueOBO
def: "A cell of benign or cancerous growth originating from kidney tissue (for example renal cell carcinoma, hypernephroma). " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "kidney carcinoma cell" RELATED []
synonym: "kidney tumor cell" RELATED []
synonym: "renal cancer cell" RELATED []
relationship: DRV BTO:0000671 ! kidney

[Term]
id: BTO:0000681
name: KM-3 cell
namespace: BrendaTissueOBO
def: "Human pre-B lymphocytic leukemia cell line." [PMID:9756922]
synonym: "KM3 cell" RELATED []
is_a: BTO:0000741 ! lymphocytic leukemia cell line

[Term]
id: BTO:0000682
name: Koji culture
namespace: BrendaTissueOBO
def: "Solid-state culture of fungus (e.g. aspergillus, penicilium) on wheat bran or other cereals." [curators:mgr]
is_a: BTO:0000214 ! cell culture
is_a: BTO:0001494 ! fungus

[Term]
id: BTO:0000683
name: Krebs ascites cell
namespace: BrendaTissueOBO
is_a: BTO:0000094 ! ascites tumor cell
is_a: BTO:0000785 ! lymphoma cell

[Term]
id: BTO:0000684
name: Krebs II ascites cell
namespace: BrendaTissueOBO
is_a: BTO:0000683 ! Krebs ascites cell

[Term]
id: BTO:0000685
name: Kupffer cell
namespace: BrendaTissueOBO
def: "Large star-shaped or pyramidal cells with a large oval nucleus and a small prominent nucleolus. These intensely phagocytic cells line the walls of the sinusoids of the liver and form a part of the reticuloendothelial system." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000801 ! macrophage
relationship: part_of BTO:0000759 ! liver
relationship: part_of BTO:0000831 ! liver reticuloendothelial system

[Term]
id: BTO:0000686
name: Kurloff cell
namespace: BrendaTissueOBO
def: "Cells found in the blood and organs of guinea pigs that contain large secretory granules but are of unknown function. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0000574 ! hematopoietic cell
relationship: part_of BTO:0000089 ! blood

[Term]
id: BTO:0000687
name: culture condition:L-mandelate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000688
name: culture condition:acetate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000689
name: culture condition:L-allo-threonine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000690
name: brain cancer cell line
namespace: BrendaTissueOBO
synonym: "brain tumor cell line" RELATED []
is_a: BTO:0000255 ! brain cell line
relationship: DRV BTO:0001573 ! brain cancer cell

[Term]
id: BTO:0000691
name: culture condition:L-fucose-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000692
name: culture condition:L-glucose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000693
name: culture condition:L-lyxose-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000694
name: culture condition:L-phenylalanine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000695
name: culture condition:L-phenylglycine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000696
name: culture condition:L-rhamnose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000697
name: culture condition:L-rhamnose-induced cell
namespace: BrendaTissueOBO
is_a: BTO:0000001 ! culture condition:-induced cell

[Term]
id: BTO:0000698
name: culture condition:L-ribose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000699
name: culture condition:L-serine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000700
name: culture condition:L-threonine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000701
name: culture condition:L-tyrosine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000702
name: L-1210 cell
namespace: BrendaTissueOBO
def: "Mouse lymphocytic leukemia established from the methylcholanthrene-induced tumor in a DBA strain mouse (subline 212, 8-month-old female) in 1949; the cells were propagated by heterotransplantation into DBA/2 mice; an in-vitro suspension culture was first reported in 1966; cells are used for cytotoxicity studies." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "L1210 cell" RELATED []
is_a: BTO:0000741 ! lymphocytic leukemia cell line

[Term]
id: BTO:0000703
name: lacquer
namespace: BrendaTissueOBO
def: "Any of various durable natural varnishes; especially: a varnish obtained from an Asian sumac (Rhus verniciflua)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=lacquer]
synonym: "Japanese lacquer" RELATED []
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0000704
name: culture condition:D-lactate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000705
name: Langerhans cell
namespace: BrendaTissueOBO
def: "Stellate dendritic cells, derived from precursors in the bone marrow, that appear clear on light microscopy and have a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; they lack tonofilaments, desmosomes, and melanosomes. Langerhans' cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. They have surface markers characteristic of macrophages and are believed to be antigen-presenting cells involved in contact allergic responses and other cell-mediated immune reactions in the skin." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000801 ! macrophage
is_a: BTO:0001470 ! epidermal cell
relationship: part_of BTO:0000435 ! stratum spinosum

[Term]
id: BTO:0000706
name: large intestine
namespace: BrendaTissueOBO
def: "The more terminal division of the vertebrate intestine that is wider and shorter than the small intestine, typically divided into cecum, colon, and rectum, and concerned especially with the resorption of water and the formation of feces." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=large+intestine]
relationship: part_of BTO:0000648 ! intestine

[Term]
id: BTO:0000707
name: larva
namespace: BrendaTissueOBO
def: "1: The immature, wingless, and often wormlike feeding form that hatches from the egg of many insects, alters chiefly in size while passing through several molts, and is finally transformed into a pupa or chrysalis from which the adult emerges.\n2: The early form of an animal (as a frog or sea urchin) that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=larva]
is_a: BTO:0000174 ! embryonic structure

[Term]
id: BTO:0000708
name: larval integument
namespace: BrendaTissueOBO
relationship: part_of BTO:0000707 ! larva

[Term]
id: BTO:0000709
name: secondary spermatocyte
namespace: BrendaTissueOBO
def: "One of the two cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids; called also prespermatid." [Dorlands Medical Dictionary:MerckSource]
synonym: "prespermatid" RELATED []
relationship: DRV BTO:0001115 ! primary spermatocyte

[Term]
id: BTO:0000710
name: latex
namespace: BrendaTissueOBO
def: "A milky usually white fluid that is produced by cells of various seed plants (as of the milkweed, spurge, and poppy families) and is the source of rubber, gutta-percha, chicle, and balata." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=latex]
synonym: "latex milk" RELATED []
relationship: part_of BTO:0000712 ! laticifer

[Term]
id: BTO:0000711
name: glioma cell line
namespace: BrendaTissueOBO
synonym: "neuroglioma cell line" RELATED []
is_a: BTO:0001531 ! glial cell line
relationship: DRV BTO:0000526 ! glioma cell

[Term]
id: BTO:0000712
name: laticifer
namespace: BrendaTissueOBO
def: "A plant cell or vessel that contains latex." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=laticifier]
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0000713
name: leaf
namespace: BrendaTissueOBO
def: "A lateral outgrowth from a plant stem that is typically a flattened expanded variably shaped greenish organ, constitutes a unit of the foliage, and functions primarily in food manufacture by photosynthesis." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=leaf]
synonym: "GRO:0005306" RELATED []
relationship: part_of BTO:0001243 ! shoot
relationship: part_of BTO:0001495 ! plumule

[Term]
id: BTO:0000714
name: leaf axil
namespace: BrendaTissueOBO
def: "The angle between a leaf and the axis from which it arises." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=axil]
relationship: part_of BTO:0000713 ! leaf

[Term]
id: BTO:0000715
name: leaf base
namespace: BrendaTissueOBO
def: "The youngest tissue at the base of the leaf." [PMID:12837815]
synonym: "GRO:0005326" RELATED []
relationship: part_of BTO:0000719 ! leaf lamina

[Term]
id: BTO:0000716
name: pancreatic beta cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000783 ! pancreatic beta cell

[Term]
id: BTO:0000717
name: pericardium
namespace: BrendaTissueOBO
def: "1: The conical sac of serous membrane that encloses the heart and the roots of the great blood vessels of vertebrates.\n2: A cavity or space that contains the heart of an invertebrate and in arthropods is a part of the hemocoel." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pericardium]
relationship: part_of BTO:0000088 ! cardiovascular system

[Term]
id: BTO:0000718
name: leaf epidermis
namespace: BrendaTissueOBO
def: "The blade consists of an upper and a lower layer of closely fitted epidermal cells, including specialized paired guard cells that control the size of tiny pores, or stomata, for gaseous exchange and the release of water vapor (see transpiration). The upper epidermis is usually coated with a waterproof cuticle and contains fewer stomata than the underside, if any at all." [The Columbia Encyclopedia:Sixth Edition. 2001]
relationship: part_of BTO:0000719 ! leaf lamina

[Term]
id: BTO:0000719
name: leaf lamina
namespace: BrendaTissueOBO
def: "The blade or flat part of a leaf." [Gramene DB:http\://dev.gramene.org/db/ontology/search/]
synonym: "GRO:0005323" RELATED []
synonym: "leaf blade" RELATED []
relationship: part_of BTO:0000713 ! leaf

[Term]
id: BTO:0000720
name: plant form
namespace: BrendaTissueOBO
is_a: BTO:0001461 ! whole plant

[Term]
id: BTO:0000721
name: leg
namespace: BrendaTissueOBO
def: "A limb of an animal used especially for supporting the body and for walking." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=leg]
is_a: BTO:0001729 ! forelimb

[Term]
id: BTO:0000722
name: leg muscle
namespace: BrendaTissueOBO
is_a: BTO:0001103 ! skeletal muscle

[Term]
id: BTO:0000723
name: lens
namespace: BrendaTissueOBO
def: "A highly transparent biconvex lens-shaped or nearly spherical body in the eye that focuses light rays (as upon the retina)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=lens]
synonym: "crystalline lens" RELATED []
synonym: "lens capsule" RELATED []
synonym: "ocular lens" RELATED []
relationship: part_of BTO:0000439 ! eye

[Term]
id: BTO:0000724
name: lens fiber
namespace: BrendaTissueOBO
relationship: part_of BTO:0000723 ! lens

[Term]
id: BTO:0000725
name: hematopoietic stem cell
namespace: BrendaTissueOBO
def: "A blood cell progenitor or mother cell representing a slightly later stage than the blast cell; it has the capacity for both replication and differentiation, and has pluripotentiality, giving rise to precursors of various different blood cell lines, such as the proerythrocyte and myeloblast, which cannot self-replicate and must differentiate into more mature daughter cells." [Dorlands Medical Dictionary:MerckSource]
synonym: "CFU-S" RELATED []
synonym: "colony forming unit spleen" RELATED []
synonym: "HSC" RELATED []
synonym: "HSC cell" RELATED []
synonym: "progenitor cell" RELATED []
is_a: BTO:0002666 ! adult stem cell
relationship: DRV BTO:0000125 ! blast cell

[Term]
id: BTO:0000726
name: RPMI-8226 cell
namespace: BrendaTissueOBO
alt_id: BTO:0003509
def: "Human multiple myeloma cell line; established from the peripheral blood of a 61-year-old man with multiple myeloma (IgG lambda-type) at diagnosis in 1966; described to produce and secrete only lambda light chains (but not heavy chains)." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "RPMI8226 cell" RELATED []
is_a: BTO:0000727 ! multiple myeloma cell line
is_a: BTO:0000849 ! melanoma cell line

[Term]
id: BTO:0000727
name: multiple myeloma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000899 ! myeloma cell line
relationship: DRV BTO:0002101 ! multiple myeloma cell

[Term]
id: BTO:0000728
name: Brown Pearce carcinoma cell
namespace: BrendaTissueOBO
def: "Brown-Pearce epithelioma in rabbit eyes (Brown and Pearce developed this eye cancer of a rabbit)." [PMID:478776]
is_a: BTO:0000176 ! carcinoma cell
is_a: BTO:0000579 ! eye cancer cell

[Term]
id: BTO:0000729
name: carcinoid cell
namespace: BrendaTissueOBO
def: "A cell of a benign or malignant tumor arising especially from the mucosa of the gastrointestinal tract." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=carcinoid]
is_a: BTO:0001533 ! gastrointestinal cancer cell
relationship: DRV BTO:0000642 ! intestinal mucosa
relationship: DRV BTO:0001308 ! gastric mucosa

[Term]
id: BTO:0000730
name: endocarp
namespace: BrendaTissueOBO
def: "The inner layer of the pericarp of a fruit (as an apple or orange) when it consists of two or more layers of different texture or consistency." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=endocarp]
synonym: "GRO:0005240" RELATED []
relationship: part_of BTO:0001017 ! pericarp

[Term]
id: BTO:0000731
name: acute lymphoblastic leukemia cell
namespace: BrendaTissueOBO
def: "Lymphocytic leukemia cell that is marked by an abnormal increase in the number of lymphoblasts, that is characterized by rapid onset and progression of symptoms which include fever, anemia, pallor, fatigue, appetite loss, bleeding, thrombocytopenia, granulocytopenia, bone and joint pain, and enlargement of the lymph nodes, liver, and spleen, and that occurs chiefly during childhood." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "acute lymphocytic leukemia cell" RELATED []
synonym: "ALL cell" RELATED []
is_a: BTO:0003676 ! lymphoblastic leukemia cell

[Term]
id: BTO:0000732
name: KU-812 cell
namespace: BrendaTissueOBO
def: "Human chronic myeloid leukemia in myeloid blast crisis, established from the peripheral blood of a 38-year-old man with chronic myeloid leukemia (CML) in myeloid blast crisis; described to express basophilic features." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "KU812 cell" RELATED []
is_a: BTO:0002580 ! chronic myeloid leukemia cell line

[Term]
id: BTO:0000733
name: exocarp
namespace: BrendaTissueOBO
def: "The outermost layer of the pericarp of a fruit.\nThe skin or rind of a fruit." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=exocarp]
synonym: "GRO:0005242" RELATED []
synonym: "peel" RELATED []
relationship: part_of BTO:0001017 ! pericarp

[Term]
id: BTO:0000734
name: myelocyte
namespace: BrendaTissueOBO
def: "A bone-marrow cell: especially:  a motile cell with cytoplasmic granules that gives rise to the blood granulocytes and occurs abnormally in the circulating blood (as in myelogenous leukemia)." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: DRV BTO:0000187 ! myeloblast

[Term]
id: BTO:0000735
name: sporophyte
namespace: BrendaTissueOBO
def: "The individual or generation of a plant exhibiting alternation of generations that bears asexual spores." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sporophyte]
is_a: BTO:0000720 ! plant form

[Term]
id: BTO:0000736
name: CCRF-CEM cell
namespace: BrendaTissueOBO
def: "Peripheral blood, T lymphoblast, acute lymphoblastic leukemia cell line. CCRF-CEM is a T lymphoblastoid cell line derived by G.E. Foley, et al. Cells were obtained in November, 1964 from peripheral blood buffy coat of a 4-year-old Caucasian female with acute lymphoblastic leukemia." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0002144 ! acute lymphoblastic leukemia cell line
is_a: BTO:0002504 ! T-lymphoblastic leukemia cell line

[Term]
id: BTO:0000737
name: leukemia cell line
namespace: BrendaTissueOBO
is_a: BTO:0001035 ! hematopoietic cell line
relationship: DRV BTO:0001271 ! leukemia cell

[Term]
id: BTO:0000738
name: HL-60 cell
namespace: BrendaTissueOBO
def: "Human acute myeloid leukemia established from the peripheral blood of a 35-year-old woman with acute myeloid leukemia (AML FAB M2) in 1976." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "HL60 cell" RELATED []
is_a: BTO:0001883 ! acute myeloid leukemia cell line

[Term]
id: BTO:0000739
name: lymphoblastic leukemia cell line
namespace: BrendaTissueOBO
def: "Lymphocytic leukemia cell line characterized by an abnormal increase in the number of lymphoblasts." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=lymphoblastic leukemia]
is_a: BTO:0000741 ! lymphocytic leukemia cell line
is_a: BTO:0000773 ! lymphoblastoid cell line

[Term]
id: BTO:0000740
name: myelocytic leukemia cell line
namespace: BrendaTissueOBO
alt_id: BTO:0002407
def: "A cell line of leukemia characterized by proliferation of myeloid tissue (as of the bone marrow and spleen) and an abnormal increase in the number of granulocytes, myelocytes, and myeloblasts in the circulating blood." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=myeloid]
synonym: "granulocytic leukemia cell line" RELATED []
synonym: "myelogenous leukemia cell line" RELATED []
synonym: "myeloid leukemia cell line" RELATED []
is_a: BTO:0000737 ! leukemia cell line
relationship: DRV BTO:0001056 ! myelocytic leukemia cell

[Term]
id: BTO:0000741
name: lymphocytic leukemia cell line
namespace: BrendaTissueOBO
is_a: BTO:0000737 ! leukemia cell line
relationship: DRV BTO:0000744 ! lymphocytic leukemia cell

[Term]
id: BTO:0000742
name: myotome
namespace: BrendaTissueOBO
def: "The portion of an embryonic somite from which skeletal musculature is produced." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=myotome]
relationship: part_of BTO:0001558 ! somite

[Term]
id: BTO:0000743
name: pre-B-lymphocyte cell line
namespace: BrendaTissueOBO
synonym: "pre-B-cell line" RELATED []
relationship: DRV BTO:0001133 ! pre-B-lymphocyte

[Term]
id: BTO:0000744
name: lymphocytic leukemia cell
namespace: BrendaTissueOBO
def: "Leukemia cell of either of two types marked by an abnormal increase in the number of white blood cells (as lymphocytes) which accumulate in bone marrow, lymphoid tissue (as of the lymph nodes and spleen), and circulating blood." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "leukemia cell, lymphocytic" RELATED []
synonym: "lymphatic leukemia cell" RELATED []
synonym: "lymphoid leukemia cell" RELATED []
is_a: BTO:0001271 ! leukemia cell

[Term]
id: BTO:0000745
name: Lewis lung carcinoma cell
namespace: BrendaTissueOBO
def: "A cell of a carcinoma discovered by dr. Margaret r. Lewis of the wistar institute in 1951. This tumour originated spontaneously as a carcinoma of the lung of a c57bl mouse. The tumour does not appear to be grossly haemorrhagic and the majority of the tumour tissue is a semifirm homogeneous mass. It is also called 3ll and llc and is used as a transplantable malignancy. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "LLC cell" RELATED []
is_a: BTO:0000551 ! lung cancer cell

[Term]
id: BTO:0000746
name: preadipocyte cell line
namespace: BrendaTissueOBO
synonym: "proadipocyte cell line" RELATED []
is_a: BTO:0003452 ! adipocyte cell line
relationship: DRV BTO:0001107 ! preadipocyte

[Term]
id: BTO:0000747
name: sporangiospore
namespace: BrendaTissueOBO
def: "A spore that develops within a sporangium. " [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
relationship: DRV BTO:0001287 ! sporangium

[Term]
id: BTO:0000748
name: P-388 cell
namespace: BrendaTissueOBO
def: "An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene." [Medical Encyclopedia:http\://www.nlm.nih.gov/medlineplus/encyclopedia.html]
synonym: "P388 cell" RELATED []
is_a: BTO:0000741 ! lymphocytic leukemia cell line

[Term]
id: BTO:0000749
name: sporozoan
namespace: BrendaTissueOBO
def: "Any of a large class (Sporozoa) of strictly parasitic protozoans that have a complicated life cycle usually involving both asexual and sexual generations often in different hosts and include important pathogens (as malaria parasites and babesias)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sporozoan]
synonym: "sporozoa" RELATED []
is_a: BTO:0002503 ! protozoan

[Term]
id: BTO:0000750
name: plant ovary
namespace: BrendaTissueOBO
def: "The enlarged rounded usually basal portion of the pistil or gynoecium of an angiospermous plant that bears the ovules and consists of one or more carpels" [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ovary]
relationship: part_of BTO:0000072 ! carpel

[Term]
id: BTO:0000751
name: leukocyte
namespace: BrendaTissueOBO
def: "Any of the blood cells that are colorless, lack hemoglobin, contain a nucleus, and include the lymphocytes, monocytes, neutrophils, eosinophils, and basophils." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=leukocyte]
synonym: "PMN cell" RELATED []
synonym: "polymorphonuclear cell" RELATED []
synonym: "white blood cell" RELATED []
is_a: BTO:0000878 ! mononuclear cell

[Term]
id: BTO:0000752
name: lymph vessel
namespace: BrendaTissueOBO
def: "A vessel that contains or conveys lymph, that originates as an interfibrillar or intercellular cleft or space in a tissue or organ, and that if small has no distinct walls or walls composed only of endothelial cells and if large resembles a vein in structure." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "lymphatic vessel" RELATED []
relationship: part_of BTO:0000570 ! hematopoietic system

[Term]
id: BTO:0000753
name: lymphoid tissue
namespace: BrendaTissueOBO
def: "Tissue that is particularly rich in lymphocytes (and accessory cells such as macrophages and reticular cells), particularly the lymph nodes, spleen, thymus, Peyer's patches, pharyngeal tonsils, adenoids, and (in birds) the Bursa of Fabricius." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000570 ! hematopoietic system

[Term]
id: BTO:0000754
name: lewy body
namespace: BrendaTissueOBO
def: "Hyaline eosinophilic concentrically-laminated inclusions found in the substantia nigra and locus ceruleus of patients with Parkinsonism and Lewy body dementia." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000143 ! substantia nigra

[Term]
id: BTO:0000755
name: Leydig cell
namespace: BrendaTissueOBO
def: "Interstitial cells of the mammalian testis, involved in synthesis of testosterone." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "interstitial cell" RELATED []
relationship: part_of BTO:0001363 ! testis

[Term]
id: BTO:0000756
name: pituitary gland tumor cell line
namespace: BrendaTissueOBO
is_a: BTO:0000427 ! pituitary gland cell line
relationship: DRV BTO:0001076 ! pituitary gland tumor cell

[Term]
id: BTO:0000757
name: plasmodium
namespace: BrendaTissueOBO
def: "Multinucleate mass of protoplasm bounded only by a plasma membrane; the main vegetative form of acellular slime moulds." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0001494 ! fungus

[Term]
id: BTO:0000758
name: myelencephalon
namespace: BrendaTissueOBO
def: "The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=myelencephalon]
relationship: part_of BTO:0000672 ! hindbrain

[Term]
id: BTO:0000759
name: liver
namespace: BrendaTissueOBO
def: "1: A large very vascular glandular organ of vertebrates that secretes bile and causes important changes in many of the substances contained in the blood (as by converting sugars into glycogen which it stores up until required and by forming urea).\n2: Any of various large compound glands associated with the digestive tract of invertebrate animals and probably concerned with the secretion of digestive enzymes." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=liver]
is_a: BTO:0000345 ! digestive gland
is_a: BTO:0001491 ! viscus

[Term]
id: BTO:0000760
name: LLC-PK1 cell
namespace: BrendaTissueOBO
def: "Pig normal kidney cell line, established from a 3- to 4-week-old male of sus scrofa." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0002578 ! LLC-PK cell

[Term]
id: BTO:0000761
name: collecting duct
namespace: BrendaTissueOBO
def: "The arcuate renal tubule, straight collecting tubule, and papillary duct considered together. " [Dorlands Medical Dictionary:MerckSource]
synonym: "renal collecting tubule" RELATED []
synonym: "tubulus renalis colligens" RELATED []
is_a: BTO:0000343 ! renal tubule

[Term]
id: BTO:0000762
name: lung cancer cell line
namespace: BrendaTissueOBO
alt_id: BTO:0002417
synonym: "lung carcinoma cell line" RELATED []
is_a: BTO:0000297 ! carcinoma cell line
is_a: BTO:0000353 ! lung cell line
relationship: DRV BTO:0000551 ! lung cancer cell

[Term]
id: BTO:0000763
name: lung
namespace: BrendaTissueOBO
def: "One of the usually paired compound saccular thoracic organs that constitute the basic respiratory organ of air-breathing vertebrates." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=lung]
is_a: BTO:0000203 ! respiratory system

[Term]
id: BTO:0000764
name: lung fibroblast
namespace: BrendaTissueOBO
is_a: BTO:0000452 ! fibroblast
relationship: part_of BTO:0000763 ! lung

[Term]
id: BTO:0000765
name: exocrine gland
namespace: BrendaTissueOBO
def: "An externally secreting gland, such as a salivary gland or sweat gland that releases its secretions directly or through a duct." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000522 ! gland

[Term]
id: BTO:0000766
name: blood vessel endothelium
namespace: BrendaTissueOBO
relationship: part_of BTO:0001102 ! blood vessel

[Term]
id: BTO:0000767
name: mesenteric lymph node
namespace: BrendaTissueOBO
def: "Nodes that lie at the root of the mesentery, receiving lymph from parts of the small intestine, cecum, appendix, and large intestine; they comprise three groups: the juxtaintestinal, central superior, and inferior mesenteric lymph nodes." [Dorlands Medical Dictionary:MerckSource]
synonym: "nodi lymphoidei mesenterici" RELATED []
is_a: BTO:0000784 ! lymph node
relationship: part_of BTO:0001380 ! mesentery

[Term]
id: BTO:0000768
name: infundibulum
namespace: BrendaTissueOBO
def: "The hollow conical process of gray matter by which the pituitary gland is continuous with the brain." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=infundibulum]
relationship: part_of BTO:0000937 ! neurohypophysis

[Term]
id: BTO:0000769
name: submandibular lymph node
namespace: BrendaTissueOBO
def: "The three to six nodes alongside the submandibular gland, through which lymph drains from the adjacent skin and mucous membrane." [Dorlands Medical Dictionary:MerckSource]
synonym: "nodi lymphoidei submandibulares" RELATED []
is_a: BTO:0000784 ! lymph node

[Term]
id: BTO:0000770
name: oligodendroglia
namespace: BrendaTissueOBO
def: "Neuroglia consisting of cells similar to but smaller than astrocytes, found in the central nervous system and associated with the formation of myelin." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000524 ! glia

[Term]
id: BTO:0000771
name: macroglia
namespace: BrendaTissueOBO
def: "Neuroglial cells of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. Originally, the term was used for the astrocytes alone." [Dorlands Medical Dictionary:MerckSource]
synonym: "macroglial cell" EXACT []
is_a: BTO:0000524 ! glia

[Term]
id: BTO:0000772
name: lymphoblast
namespace: BrendaTissueOBO
def: "Often referred to as a blast cell. Unlike other usages of the suffix -blast a lymphoblast is a further differentiation of a lymphocyte, T- or B-, occasioned by an antigenic stimulus. The lymphoblast usually develops by enlargement of a lymphocyte, active re-entry to the S phase of the cell cycle, mitogenesis and production of much m-RNA and ribosomes." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000775 ! lymphocyte

[Term]
id: BTO:0000773
name: lymphoblastoid cell line
namespace: BrendaTissueOBO
def: "Human cell line from tissue infected with Epstein-Barr virus, resembling a lymphoblast." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "lymphoblastoid cell" RELATED []
relationship: DRV BTO:0000772 ! lymphoblast

[Term]
id: BTO:0000774
name: lymphoblastoma cell
namespace: BrendaTissueOBO
def: "A cell of any of several diseases of lymph nodes marked by the formation of tumorous masses composed of mature or immature lymphocytes . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: DRV BTO:0000784 ! lymph node

[Term]
id: BTO:0000775
name: lymphocyte
namespace: BrendaTissueOBO
def: "Any of the colorless weakly motile cells originating from stem cells and differentiating in lymphoid tissue (as of the thymus or bone marrow) that are the typical cellular elements of lymph, include the cellular mediators of immunity, and constitute 20 to 30 percent of the white blood cells of normal human blood." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=lymphocyte]
is_a: BTO:0000751 ! leukocyte
is_a: BTO:0001096 ! lymphoid cell

[Term]
id: BTO:0000776
name: B-lymphocyte
namespace: BrendaTissueOBO
def: "Any of the lymphocytes that have antibody molecules on the surface and comprise the antibody-secreting plasma cells when mature." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=B+cell]
synonym: "B cell" RELATED []
synonym: "B lymphocyte" RELATED []
synonym: "B-cell" RELATED []
is_a: BTO:0000775 ! lymphocyte

[Term]
id: BTO:0000777
name: adenoid
namespace: BrendaTissueOBO
def: "An enlarged mass of lymphoid tissue at the back of the pharynx characteristically obstructing breathing." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=adenoid]
synonym: "pharyngeal tonsil" RELATED []
is_a: BTO:0000753 ! lymphoid tissue
relationship: REL BTO:0001049 ! pharynx

[Term]
id: BTO:0000778
name: pulmonary artery
namespace: BrendaTissueOBO
def: "An artery that conveys venous blood from the heart to the lungs." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pulmonary+artery]
is_a: BTO:0000573 ! artery

[Term]
id: BTO:0000779
name: mesenteric artery
namespace: BrendaTissueOBO
def: "Either of two arteries arising from the aorta and passing between the two layers of the mesentery to the intestine:  a:  one that arises just above the bifurcation of the abdominal aorta into the common iliac arteries and supplies the left half of the transverse colon, the descending colon, the sigmoid colon, and most of the rectum - called also inferior mesenteric artery   b:  a large artery that arises from the aorta just below the celiac artery at the level of the first lumbar vertebra and supplies the greater part of the small intestine, the cecum, the ascending colon, and the right half of the transverse colon." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "superior mesenteric artery" RELATED []
is_a: BTO:0000573 ! artery

[Term]
id: BTO:0000780
name: alveolar cell type I
namespace: BrendaTissueOBO
def: "The flattened cells of the alveolar epithelium, distinguished by their greatly attenuated cytoplasm and paucity of organelles." [Dorlands Medical Dictionary:MerckSource]
synonym: "membranous pneumocyte" RELATED []
synonym: "small alveolar cell" RELATED []
synonym: "squamous alveolar cell" RELATED []
is_a: BTO:0000395 ! alveolar cell

[Term]
id: BTO:0000781
name: intestinal epithelium
namespace: BrendaTissueOBO
def: "The endodermally-derived epithelium of the intestine varies considerably, but the absorptive epithelium of small intestine is usually implied." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0000648 ! intestine

[Term]
id: BTO:0000782
name: T-lymphocyte
namespace: BrendaTissueOBO
def: "Any of several lymphocytes (as a helper T cell) that differentiate in the thymus, possess highly specific cell-surface antigen receptors, and include some that control the initiation or suppression of cell-mediated and humoral immunity (as by the regulation of T and B cell maturation and proliferation) and others that lyse antigen-bearing cells." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=T+cell]
synonym: "T cell" RELATED []
synonym: "T lymphocyte" RELATED []
synonym: "T-cell" RELATED []
is_a: BTO:0000775 ! lymphocyte

[Term]
id: BTO:0000783
name: pancreatic beta cell
namespace: BrendaTissueOBO
def: "One of the cells that compose the bulk of the islets of Langerhans and secrete insulin." [Dorlands Medical Dictionary:MerckSource]
synonym: "beta cell" RELATED []
relationship: part_of BTO:0000991 ! pancreatic islet

[Term]
id: BTO:0000784
name: lymph node
namespace: BrendaTissueOBO
def: "Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=lymph+node]
synonym: "lymph gland" RELATED []
is_a: BTO:0000753 ! lymphoid tissue
is_a: BTO:0001488 ! endocrine gland

[Term]
id: BTO:0000785
name: lymphoma cell
namespace: BrendaTissueOBO
def: "A tumor cell of lymphoid tissue." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=lymphoma]
synonym: "lymph node cancer cell" RELATED []
synonym: "lymphadenoma cell" RELATED []
is_a: BTO:0000580 ! blood cancer cell
relationship: DRV BTO:0000753 ! lymphoid tissue

[Term]
id: BTO:0000786
name: tongue cancer cell line
namespace: BrendaTissueOBO
is_a: BTO:0000885 ! tongue cell line

[Term]
id: BTO:0000787
name: gastric cancer cell line
namespace: BrendaTissueOBO
is_a: BTO:0001088 ! gastric cell line
relationship: DRV BTO:0000498 ! gastric cancer cell

[Term]
id: BTO:0000788
name: 70Z/3 cell
namespace: BrendaTissueOBO
def: "Mouse, (C57BL/6xDBA/2)F1, blood, leukemia, pre-B cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000603 ! pre-B acute lymphoblastic leukemia cell line
is_a: BTO:0000743 ! pre-B-lymphocyte cell line

[Term]
id: BTO:0000789
name: CA-46 cell
namespace: BrendaTissueOBO
def: "Human Burkitt's lymphoma, established from the ascites fluid of a patient with American-type Burkitt's lymphoma." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "CA46 cell" RELATED []
is_a: BTO:0000889 ! Burkitt lymphoma cell line

[Term]
id: BTO:0000790
name: pharyngeal cancer cell line
namespace: BrendaTissueOBO
synonym: "pharynx carcinoma cell line" RELATED []
is_a: BTO:0000819 ! pharyngeal cell line

[Term]
id: BTO:0000791
name: BW-5147 cell
namespace: BrendaTissueOBO
def: "Mouse AKR/J thymic lymphoma cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "BW5147 cell" RELATED []
is_a: BTO:0001377 ! thymus lymphoma cell line

[Term]
id: BTO:0000792
name: urinary bladder cancer cell line
namespace: BrendaTissueOBO
synonym: "urinary bladder carcinoma cell line" RELATED []
is_a: BTO:0000096 ! urinary bladder cell line
relationship: DRV BTO:0000362 ! urinary bladder cancer cell

[Term]
id: BTO:0000793
name: SH-SY5Y cell
namespace: BrendaTissueOBO
def: "Human neuroblastoma clonal subline of the neuroepithelioma cell line SK-N-SH that had been established in 1970 from the bone marrow biopsy of a 4-year-old girl with metastatic neuroblastoma." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "SHSY-5Y cell" RELATED []
synonym: "SK-N-SH-SY5Y cell" RELATED []
synonym: "SY5Y cell" RELATED []
relationship: DRV BTO:0001620 ! SK-N-SH cell

[Term]
id: BTO:0000794
name: pancreatic cancer cell line
namespace: BrendaTissueOBO
is_a: BTO:0000183 ! pancreatic cell line
relationship: DRV BTO:0000584 ! pancreatic cancer cell

[Term]
id: BTO:0000795
name: L-5178-Y cell
namespace: BrendaTissueOBO
def: "Mouse T cell lymphoma, established from an 8-month-old female DBA/2 mouse with T cell lymphoma in 1985." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "L5178Y cell" RELATED []
is_a: BTO:0003212 ! T-lymphoma cell line

[Term]
id: BTO:0000796
name: P-1798 cell
namespace: BrendaTissueOBO
def: "Mouse T-lymphoma cell line." [PMID:6238026]
is_a: BTO:0003212 ! T-lymphoma cell line

[Term]
id: BTO:0000797
name: colonic cancer cell line
namespace: BrendaTissueOBO
synonym: "colon cancer cell line" RELATED []
synonym: "colon carcinoma cell line" RELATED []
synonym: "colonic carcinoma cell line" RELATED []
is_a: BTO:0000188 ! colonic cell line
relationship: DRV BTO:0000586 ! colonic cancer cell

[Term]
id: BTO:0000798
name: BeWo cell
namespace: BrendaTissueOBO
def: "Human placenta choriocarcinoma cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "BEWO cell" RELATED []
is_a: BTO:0001575 ! choriocarcinoma cell line

[Term]
id: BTO:0000799
name: lymphosarcoma cell
namespace: BrendaTissueOBO
def: "A malignant lymphoma cell that tends to metastasize freely especially along the regional lymphatic drainage." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=lymphosarcoma]
is_a: BTO:0000785 ! lymphoma cell
is_a: BTO:0001207 ! sarcoma cell

[Term]
id: BTO:0000800
name: endoderm
namespace: BrendaTissueOBO
def: "A germ layer lying remote from the surface of the embryo that gives rise to internal tissues such as gut." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "hypoblast" RELATED []
is_a: BTO:0000556 ! germ layer

[Term]
id: BTO:0000801
name: macrophage
namespace: BrendaTissueOBO
def: "Relatively long-lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kuppfer cells of the liver, and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa, and tumour cells, release substances that stimulate other cells of the immune system, and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans' giant cells." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "macrophagocyte" RELATED []
relationship: DRV BTO:0000876 ! monocyte

[Term]
id: BTO:0000802
name: alveolar macrophage
namespace: BrendaTissueOBO
def: "Macrophage found in lung and that can be obtained by lung lavage; responsible for clearance of inhaled particles and lung surfactant. Metabolism slightly different from peritoneal macrophages (more oxidative metabolism), often have multivesicular bodies that may represent residual undigested lung surfactant." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "alveolar phagocyte" RELATED []
synonym: "dust cell" RELATED []
is_a: BTO:0000801 ! macrophage

[Term]
id: BTO:0000803
name: pancreatic delta cell
namespace: BrendaTissueOBO
def: "A type of cell in the pancreatic islets that secretes somatostatin." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000991 ! pancreatic islet

[Term]
id: BTO:0000804
name: J-774A.1 cell
namespace: BrendaTissueOBO
def: "Mouse monocytes-macrophages, established from a tumor in a female BALB/c mouse in 1968; cells were described to synthesize lysozyme and interleukin-1 and to have receptors for immunoglobulin and complement." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "J774A.1 cell" RELATED []
is_a: BTO:0002279 ! J-774 cell

[Term]
id: BTO:0000805
name: pancreatic PP cell
namespace: BrendaTissueOBO
def: "Cells in the pancreatic islets, exocrine pancreas, and intestine that secrete pancreatic polypeptide. " [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000434 ! exocrine pancreas
relationship: part_of BTO:0000651 ! small intestine
relationship: part_of BTO:0000991 ! pancreatic islet

[Term]
id: BTO:0000806
name: IC-21 cell
namespace: BrendaTissueOBO
def: "Mouse peritoneal macrophage, SV40 transformed. The IC-21 cell line was derived by transformation of normal C57BL/6 mouse peritoneal macrophages with SV40." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0001008 ! PBMC cell line

[Term]
id: BTO:0000807
name: chorionic cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000252 ! chorion

[Term]
id: BTO:0000808
name: interrenal gland
namespace: BrendaTissueOBO
def: "Structures in fishes homologous to the cortical tissue of the mammalian adrenal gland; they are in close proximity to or imbedded in the kidney. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "interrenal body" RELATED []
is_a: BTO:0001488 ! endocrine gland

[Term]
id: BTO:0000809
name: germ cell cancer cell
namespace: BrendaTissueOBO
synonym: "germ cell tumor cell" RELATED []
relationship: DRV BTO:0000535 ! germ cell

[Term]
id: BTO:0000810
name: malpighian tubule
namespace: BrendaTissueOBO
def: "Any of a group of long blind vessels opening into the posterior part of the alimentary canal in most insects and some other arthropods and functioning primarily as excretory organs." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=malphigian+tubule]
synonym: "malphigian tube" RELATED []
is_a: BTO:0000431 ! excretory gland
is_a: BTO:0001491 ! viscus

[Term]
id: BTO:0000811
name: ovary cancer cell line
namespace: BrendaTissueOBO
synonym: "ovarian cancer cell line" RELATED []
synonym: "ovarian carcinoma cell line" RELATED []
is_a: BTO:0000977 ! ovary cell line
relationship: DRV BTO:0001023 ! ovary cancer cell

[Term]
id: BTO:0000812
name: OVCAR-3 cell
namespace: BrendaTissueOBO
def: "Human, Caucasian, ovary, adenocarcinoma cell line. Species: human, Caucasian female 60 years old; Tissue: ovary; Tumor: adenocarcinoma; Derived from: ascitic fluid." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0001882 ! ovary adenocarcinoma cell line

[Term]
id: BTO:0000813
name: Pt-K1 cell
namespace: BrendaTissueOBO
def: "Marsupial - potoroo, kidney cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "Pt K1 cell" RELATED []
is_a: BTO:0000067 ! kidney cell line

[Term]
id: BTO:0000814
name: CAOV-3 cell
namespace: BrendaTissueOBO
def: "Human ovarian adenocarcinoma cell line; established from a 54-year-old caucasian female." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000167 ! adenocarcinoma cell line
is_a: BTO:0001882 ! ovary adenocarcinoma cell line

[Term]
id: BTO:0000815
name: MDA-MB-231 cell
namespace: BrendaTissueOBO
alt_id: BTO:0003038
def: "Human caucasian, breast adenocarcinoma cell line; established from a  51-years-old caucasian female; Tissue: breast; Tumor: adenocarcinoma; Derived from: pleural effusion." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "HTB-26 cell" RELATED []
synonym: "HTB26 cell" RELATED []
synonym: "MDA-231 cell" RELATED []
synonym: "MDA-MB231 cell" RELATED []
is_a: BTO:0000356 ! breast cancer cell line
is_a: BTO:0001912 ! breast adenocarcinoma cell line

[Term]
id: BTO:0000816
name: breast cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000149 ! breast

[Term]
id: BTO:0000817
name: mammary gland
namespace: BrendaTissueOBO
def: "The specialized accessory gland of the skin of female mammals that secretes milk. In the human female, it is a compound tubuloalveolar gland composed of 15 to 25 lobes arranged radially about the nipple and separated by connective and adipose tissue, each lobe having its own excretory (lactiferous) duct opening on the nipple. The lobes are subdivided into lobules, with the alveolar ducts and alveoli being the secretory portion of the gland." [Dorlands Medical Dictionary:MerckSource]
synonym: "glandula mammaria" RELATED []
synonym: "lactiferous gland" RELATED []
synonym: "mamma" RELATED []
relationship: part_of BTO:0000149 ! breast

[Term]
id: BTO:0000818
name: spinal column
namespace: BrendaTissueOBO
def: "The series of articulated vertebrae, separated by intervertebral disks and held together by muscles and tendons, that extends from the cranium to the coccyx or the end of the tail, encasing the spinal cord and forming the supporting axis of the body; the spine." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "backbone" RELATED []
synonym: "columna vertebralis" RELATED []
synonym: "dorsal spine" RELATED []
synonym: "vertebral column" RELATED []
relationship: part_of BTO:0001486 ! skeletal system

[Term]
id: BTO:0000819
name: pharyngeal cell line
namespace: BrendaTissueOBO
synonym: "pharynx cell line" RELATED []
relationship: DRV BTO:0001049 ! pharynx

[Term]
id: BTO:0000820
name: C127I cell
namespace: BrendaTissueOBO
def: "Mouse mammary gland cell line. C127I cells are suitable hosts for transformation with bovine papilloma virus DNA plasmids." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0003568 ! mammary gland cell line

[Term]
id: BTO:0000821
name: nipple
namespace: BrendaTissueOBO
def: "The protuberance of a mammary gland upon which in the female the lactiferous ducts open and from which milk is drawn." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nipple]
relationship: part_of BTO:0000817 ! mammary gland

[Term]
id: BTO:0000822
name: culture condition:mandelate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000823
name: cerebral gray matter
namespace: BrendaTissueOBO
def: "Brownish-gray nerve tissue, especially of the brain and spinal cord, composed of nerve cell bodies and their dendrites and some supportive tissue" [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "gray matter" RELATED []
relationship: part_of BTO:0000142 ! brain
relationship: part_of BTO:0001279 ! spinal cord

[Term]
id: BTO:0000824
name: culture condition:mannose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000825
name: mantle
namespace: BrendaTissueOBO
def: "A fold or lobe or pair of lobes of the body wall of a mollusk or brachiopod that in shell-bearing forms lines the shell and bears shell-secreting glands." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=mantle]
synonym: "mantle tissue" RELATED []
is_a: BTO:0000139 ! body wall

[Term]
id: BTO:0000826
name: mantle cavity
namespace: BrendaTissueOBO
def: "Within the shell is a fleshy layer of tissue called the mantle; there is a cavity (the mantle cavity) between the mantle and the body wall proper." [The Columbia Encyclopedia:Sixth Edition. 2001]
relationship: part_of BTO:0000825 ! mantle

[Term]
id: BTO:0000827
name: mantle muscle
namespace: BrendaTissueOBO
relationship: part_of BTO:0000825 ! mantle
relationship: part_of BTO:0001266 ! invertebrate muscular system

[Term]
id: BTO:0000828
name: throat
namespace: BrendaTissueOBO
def: ":. The part of the neck in front of the spinal column.\n2: The passage through the neck to the stomach and lungs." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=throat]
relationship: part_of BTO:0000420 ! neck

[Term]
id: BTO:0000829
name: marrow
namespace: BrendaTissueOBO
def: "1: A soft highly vascular modified connective tissue that occupies the cavities and cancellous part of most bones.\n2: The substance of the spinal cord." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=marrow]
is_a: BTO:0000421 ! connective tissue

[Term]
id: BTO:0000830
name: mast cell
namespace: BrendaTissueOBO
def: "A large cell that occurs especially in connective tissue and has basophilic granules containing substances (as histamine and heparin) which mediate allergic reactions." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=mast+cell]
synonym: "labrocyte" RELATED []
synonym: "mastocyte" RELATED []
is_a: BTO:0000421 ! connective tissue

[Term]
id: BTO:0000831
name: liver reticuloendothelial system
namespace: BrendaTissueOBO
is_a: BTO:0001174 ! reticuloendothelial system

[Term]
id: BTO:0000832
name: mastocytoma cell
namespace: BrendaTissueOBO
def: "A nodule of mast cells. Mastocytomas can involve the skin, subcutaneous tissue, and sometimes muscle. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "mast cell tumor cell" RELATED []
relationship: DRV BTO:0000830 ! mast cell

[Term]
id: BTO:0000833
name: RBL-2H3 cell
namespace: BrendaTissueOBO
def: "Rat basophilic leukemia; the rat basophlic leukemia (RBL) line was originally obtained by Eccleston et al. and was maintained by serial passage in neonatal Wistar rats; four cell lines (named RBL I-IV) were started from this tumor between 1973 and 1975; the subline RBL-IV HR+ was derived from RBL-IV; further subcloning established the cell line RBL-2H3; cells are described to release histamine as an IgE-mediated reaction." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "RBL2H3 cell" RELATED []
is_a: BTO:0001018 ! basophilic leukemia cell line

[Term]
id: BTO:0000834
name: Detroit 562 cell
namespace: BrendaTissueOBO
def: "Human, Caucasian female, pharynx, carcinoma cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000790 ! pharyngeal cancer cell line

[Term]
id: BTO:0000835
name: culture condition:L-idonate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000836
name: MDBK cell
namespace: BrendaTissueOBO
def: "The MDBK cell line was derived from a kidney of an apparently normal adult steer, February 18, 1957, by S.H. Madin and N.B. Darby. " [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000067 ! kidney cell line

[Term]
id: BTO:0000837
name: MDCK cell
namespace: BrendaTissueOBO
def: "The MDCK cell line was derived from a kidney of an apparently normal adult female cocker spaniel, September, 1958, by S.H. Madin and N.B. Darby. The cells are positive for keratin by immunoperoxidase staining. MDCK cells have been used to study processing of beta amyloid precursor protein and sorting of its proteolytic products." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "Madin-Darby canine kidney cell line" RELATED []
is_a: BTO:0000067 ! kidney cell line

[Term]
id: BTO:0000838
name: meconium
namespace: BrendaTissueOBO
def: "A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=meconium]
relationship: DRV BTO:0000449 ! fetus

[Term]
id: BTO:0000839
name: mesoderm
namespace: BrendaTissueOBO
def: "Middle of the three germ layers, gives rise to the musculoskeletal, blood, vascular and urinogenital systems, to connective tissue (including that of dermis) and contributes to some glands. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0000556 ! germ layer

[Term]
id: BTO:0000840
name: nose
namespace: BrendaTissueOBO
def: "1a: The part of the face that bears the nostrils and covers the anterior part of the nasal cavity; broadly: this part together with the nasal cavity.\nb: The anterior part of the head at the top or end of the muzzle: snout, proboscis.\n2. The vertebrate olfactory organ." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nose]
is_a: BTO:0000202 ! sense organ
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0000841
name: umbilical artery
namespace: BrendaTissueOBO
def: "Either of a pair of arteries that arise from the hypogastric arteries of the mammalian fetus and pass through the umbilical cord to the placenta to which they carry the deoxygenated blood from the fetus." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000573 ! artery
is_a: BTO:0001847 ! umbilical smooth muscle
relationship: part_of BTO:0001415 ! umbilical cord

[Term]
id: BTO:0000842
name: megagametophyte
namespace: BrendaTissueOBO
def: "The female gametophyte produced by a megaspore." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=megagametophyte]
synonym: "embryo sac" RELATED []
synonym: "female gametophyte" RELATED []
synonym: "GRO:0000188" RELATED []
is_a: BTO:0000495 ! gametophyte
relationship: part_of BTO:0001777 ! megasporangium

[Term]
id: BTO:0000843
name: megakaryocyte
namespace: BrendaTissueOBO
def: "A large cell that has a lobulated nucleus, is found especially in the bone marrow, and is the source of blood platelets." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=megakaryocyte]
synonym: "megacaryocyte" RELATED []
is_a: BTO:0001441 ! marrow cell
relationship: DRV BTO:0001164 ! megakaryoblast

[Term]
id: BTO:0000844
name: megakaryotic cell line
namespace: BrendaTissueOBO
is_a: BTO:0000264 ! bone marrow cell line

[Term]
id: BTO:0000845
name: meiotic cell
namespace: BrendaTissueOBO
def: "A cell that undergoes meiosis: the cellular process that results in the number of chromosomes in gamete-producing cells being reduced to one half and that involves a reduction division in which one of each pair of homologous chromosomes passes to each daughter cell and a mitotic division." [curators:mgr, From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=meiosis]
synonym: "meiocyte" RELATED []
is_a: BTO:0001434 ! vegetative cell

[Term]
id: BTO:0000846
name: erythroleukemia cell line
namespace: BrendaTissueOBO
is_a: BTO:0000737 ! leukemia cell line
relationship: DRV BTO:0000426 ! erythroleukemia cell

[Term]
id: BTO:0000847
name: melanocyte
namespace: BrendaTissueOBO
def: "An epidermal cell that produces melanin." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=melanocyte]
is_a: BTO:0001470 ! epidermal cell

[Term]
id: BTO:0000848
name: melanoma cell
namespace: BrendaTissueOBO
def: "A cell of a form of skin cancer that arises in melanocytes, the cells that produce pigment. Melanoma usually begins in a mole. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
is_a: BTO:0001286 ! skin cancer cell
relationship: DRV BTO:0000847 ! melanocyte

[Term]
id: BTO:0000849
name: melanoma cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000848 ! melanoma cell

[Term]
id: BTO:0000850
name: amelanotic melanoma cell
namespace: BrendaTissueOBO
def: "A cell of unpigmented malignant melanoma." [Dorlands Medical Dictionary:MerckSource]
synonym: "melanoma cell, amelanotic" RELATED []
is_a: BTO:0000848 ! melanoma cell

[Term]
id: BTO:0000851
name: adrenal cortex cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000045 ! adrenal cortex

[Term]
id: BTO:0000852
name: meristem
namespace: BrendaTissueOBO
def: "A formative plant tissue usually made up of small cells capable of dividing indefinitely and giving rise to similar cells or to cells that differentiate to produce the definitive tissues and organs." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=meristem]
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0000853
name: mesangial cell
namespace: BrendaTissueOBO
def: "Cell found within the glomerular lobules of mammalian kidney, where they serve as structural supports, may regulate blood flow, are phagocytic, and may act as accessory cells, presenting antigen in immune responses." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0002494 ! mesangium

[Term]
id: BTO:0000854
name: zygote
namespace: BrendaTissueOBO
def: "Diploid cell resulting from the fusion of male and female gametes at fertilization." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000174 ! embryonic structure

[Term]
id: BTO:0000855
name: lymph
namespace: BrendaTissueOBO
def: "A clear, watery, sometimes faintly yellowish fluid derived from body tissues that contains white blood cells and circulates throughout the lymphatic system, returning to the venous bloodstream through the thoracic duct. Lymph acts to remove bacteria and certain proteins from the tissues, transport fat from the small intestine, and supply mature lymphocytes to the blood." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000570 ! hematopoietic system

[Term]
id: BTO:0000856
name: mesocarp
namespace: BrendaTissueOBO
def: "The middle layer of a pericarp." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=mesocarp]
synonym: "GRO:0005238" RELATED []
relationship: part_of BTO:0001017 ! pericarp
relationship: part_of BTO:0001142 ! pulp

[Term]
id: BTO:0000857
name: umbilical artery endothelium
namespace: BrendaTissueOBO
is_a: BTO:0000393 ! endothelium
relationship: part_of BTO:0000841 ! umbilical artery

[Term]
id: BTO:0000858
name: mesophyll
namespace: BrendaTissueOBO
def: "The photosynthetic parenchyma between the epidermal layers of a foliage leaf." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=mesophyll]
synonym: "GRO:0005645" RELATED []
relationship: part_of BTO:0000718 ! leaf epidermis

[Term]
id: BTO:0000859
name: metacestode
namespace: BrendaTissueOBO
def: "The larval (metacestode) stage of the tapeworm Echinococcus multilocularis." [PMID:9593125]
is_a: BTO:0000707 ! larva
is_a: BTO:0002306 ! cestode

[Term]
id: BTO:0000860
name: CHRB30 cell
namespace: BrendaTissueOBO
def: "Chinese hamster ovary cell line." [PMID:9099718]
is_a: BTO:0000977 ! ovary cell line

[Term]
id: BTO:0000861
name: culture condition:methanol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000862
name: heart ventricle
namespace: BrendaTissueOBO
def: "A chamber of the heart which receives blood from a corresponding atrium and from which blood is forced into the arteries." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ventricle]
synonym: "cardiac ventricle" RELATED []
relationship: part_of BTO:0000562 ! heart

[Term]
id: BTO:0000863
name: midgut
namespace: BrendaTissueOBO
def: "The middle part of an alimentary canal." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=midgut]
relationship: part_of BTO:0000545 ! gut

[Term]
id: BTO:0000864
name: tibialis
namespace: BrendaTissueOBO
def: "Either of two muscles of the calf of the leg." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000722 ! leg muscle
is_a: BTO:0001257 ! flexor

[Term]
id: BTO:0000865
name: anterior spinal root
namespace: BrendaTissueOBO
def: "The motor division of each spinal nerve, attached centrally to the spinal cord and joining peripherally with the corresponding posterior (sensory) root to form the nerve before it emerges through the intervertebral foramen. It conveys motor fibers to skeletal muscle and contains preganglionic autonomic fibers at thoracolumbar and sacral levels. There are 31 anterior and 31 posterior roots: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Called also ventral or motor root of spinal nerve, root ventralis nervi spinalis, and root motoria nervi spinalis." [Dorlands Medical Dictionary:MerckSource]
synonym: "anterior root of spinal nerve" RELATED []
synonym: "motor root of spinal nerve" RELATED []
synonym: "motor spinal root" RELATED []
synonym: "radix anterior nervi spinalis" RELATED []
synonym: "root motoria nervi spinalis" RELATED []
synonym: "root ventralis nervi spinalis" RELATED []
synonym: "ventral root of spinal nerve" RELATED []
relationship: part_of BTO:0000883 ! spinal root

[Term]
id: BTO:0000866
name: midgut secretion
namespace: BrendaTissueOBO
relationship: DRV BTO:0000597 ! hepatopancreas

[Term]
id: BTO:0000867
name: tibialis posterior
namespace: BrendaTissueOBO
def: "A deeply situated muscle that arises from the tibia and fibula, interosseous membrane, and intermuscular septa, that is inserted by a tendon passing under the medial malleolus into the navicular and first cuneiform bones, and that flexes the foot in the direction of the sole and tends to invert it." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "ibialis posticus" RELATED []
synonym: "posterior tibialis" RELATED []
synonym: "tibialis posterior muscle" RELATED []
is_a: BTO:0000864 ! tibialis

[Term]
id: BTO:0000868
name: milk
namespace: BrendaTissueOBO
def: "A fluid secreted by the mammary glands of females for the nourishment of their young; especially: cow's milk used as a food by humans." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=milk]
relationship: DRV BTO:0000817 ! mammary gland

[Term]
id: BTO:0000869
name: milk fat
namespace: BrendaTissueOBO
def: "The suspension in milk which tends to separate out as cream." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000868 ! milk

[Term]
id: BTO:0000870
name: spinal nerve
namespace: BrendaTissueOBO
def: "Any of the paired nerves which leave the spinal cord of a craniate vertebrate, supply muscles of the trunk and limbs, and connect with the nerves of the sympathetic nervous system, which arise by a short motor ventral root and a short sensory dorsal root, and of which there are 31 pairs in humans classified according to the part of the spinal cord from which they arise into 8 cervical pairs, 12 thoracic pairs, 5 lumbar pairs, 5 sacral pairs, and one coccygeal pair." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spinal+nerve]
is_a: BTO:0000925 ! nerve
relationship: part_of BTO:0001028 ! peripheral nervous system

[Term]
id: BTO:0000871
name: RAG cell
namespace: BrendaTissueOBO
def: "Mouse, BALB/cd, kidney, adenocarcinoma cell line. Derived from the original Renal-2a BALB/cd renal adenocarcinoma. Cells produce the unique kidney specific esterase ES-2 and have been used in somatic cell hybridisation studies because of their azaguanine resistant properties." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000167 ! adenocarcinoma cell line
is_a: BTO:0000383 ! renal cell carcinoma cell line

[Term]
id: BTO:0000872
name: oligodendrocytic cell line
namespace: BrendaTissueOBO
synonym: "oligondendrocyte cell line" RELATED []
relationship: DRV BTO:0000962 ! oligodendrocyte
relationship: DRV BTO:0001531 ! glial cell line

[Term]
id: BTO:0000873
name: MOLT-4 cell
namespace: BrendaTissueOBO
def: "Human T cell leukemia established from the peripheral blood of a 19-year-old man with acute lymphoblastic leukemia (ALL) in relapse in 1971; sister cell line of MOLT-3." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "MOLT4 cell" RELATED []
is_a: BTO:0002144 ! acute lymphoblastic leukemia cell line
is_a: BTO:0002504 ! T-lymphoblastic leukemia cell line

[Term]
id: BTO:0000874
name: molting gland
namespace: BrendaTissueOBO
def: "Either of a pair of endocrine glands located in the prothorax of certain insects and regulating molting." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "prothoracic gland" RELATED []
synonym: "Y-organ" RELATED []
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0000707 ! larva
relationship: part_of BTO:0001143 ! pupa
relationship: part_of BTO:0001368 ! thorax

[Term]
id: BTO:0000875
name: N20.1 cell
namespace: BrendaTissueOBO
def: "Oligodendrocytic cell line." [PMID:10037476]
is_a: BTO:0000872 ! oligodendrocytic cell line

[Term]
id: BTO:0000876
name: monocyte
namespace: BrendaTissueOBO
def: "A mononuclear phagocytic leukocyte, 13 to 25 mm in diameter, with an ovoid or kidney-shaped nucleus, containing lacy, linear chromatin and abundant gray-blue cytoplasm filled with fine reddish and azurophilic granules. Formed in the bone marrow from promonocytes, monocytes are transported to tissues such as the lung and liver, where they develop into macrophages." [Dorlands Medical Dictionary:MerckSource]
synonym: "mononuclear leukocyte" RELATED []
synonym: "nongranular leukocyte" RELATED []
is_a: BTO:0000751 ! leukocyte
is_a: BTO:0001433 ! mononuclear phagocyte

[Term]
id: BTO:0000877
name: culture condition:trehalose-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000878
name: mononuclear cell
namespace: BrendaTissueOBO
def: "A cell having only one nucleus, especially: MONOCYTE." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000574 ! hematopoietic cell

[Term]
id: BTO:0000879
name: lateral ventricle
namespace: BrendaTissueOBO
def: "An internal cavity in each cerebral hemisphere that consists of a central body and three cornua including an anterior one curving forward and outward, a posterior one curving backward, and an inferior one curving downward." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0001442 ! brain ventricle

[Term]
id: BTO:0000880
name: culture condition:alkane-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000881
name: Morris hepatoma 7777 cell
namespace: BrendaTissueOBO
def: "Morris hepatoma 7777 is obtained from a male Buffalo strain rat, induced with N-2 fluorenylphthalamic acid." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0001080 ! Morris hepatoma cell

[Term]
id: BTO:0000882
name: culture condition:p-hydroxyphenylacetic acid-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000883
name: spinal root
namespace: BrendaTissueOBO
def: "The anterior and posterior roots of the spinal nerves." [Dorlands Medical Dictionary:MerckSource]
synonym: "nerve root" RELATED []
relationship: part_of BTO:0000870 ! spinal nerve

[Term]
id: BTO:0000884
name: molting fluid
namespace: BrendaTissueOBO
def: "Arthropods (e.g., insects and crustaceans) must molt their exoskeletons periodically in order to grow; in this process the inner layers of the old cuticle are digested by a molting fluid secreted by the epidermal cells, the animal emerges from the old covering, and the new cuticle hardens." [The Columbia Encyclopedia:Sixth Edition. 2001]
synonym: "moulting fluid" RELATED []
relationship: DRV BTO:0000874 ! molting gland

[Term]
id: BTO:0000885
name: tongue cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001385 ! tongue

[Term]
id: BTO:0000886
name: mucosa
namespace: BrendaTissueOBO
def: "A membrane lining all body passages that communicate with the air, such as the respiratory and alimentary tracts, and having cells and associated glands that secrete mucus." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "mucous membrane" RELATED []
synonym: "tunica mucosa" RELATED []
is_a: BTO:0000634 ! integument

[Term]
id: BTO:0000887
name: muscle
namespace: BrendaTissueOBO
def: "A body tissue consisting of long cells that contract when stimulated and produce motion." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=muscle]
is_a: BTO:0001485 ! muscular system

[Term]
id: BTO:0000888
name: muscle fibre
namespace: BrendaTissueOBO
def: "An elongated contractile cell that forms the muscles of the body." [TheFreeDictionary.com:http\://www.thefreedictionary.com/muscle]
synonym: "muscle cell" RELATED []
synonym: "muscle fiber" RELATED []
relationship: part_of BTO:0000887 ! muscle

[Term]
id: BTO:0000889
name: Burkitt lymphoma cell line
namespace: BrendaTissueOBO
synonym: "Burkitt's lymphoma cell line" RELATED []
is_a: BTO:0000104 ! lymphoma cell line
relationship: DRV BTO:0000164 ! Burkitt lymphoma cell

[Term]
id: BTO:0000890
name: mycelial felt
namespace: BrendaTissueOBO
def: "Mass of hyphae, usually in wood or bark; visible with the naked eye." [Concepts in Mycology:http\://facstaff.bloomu.edu/chamuris/text/glossary.html]
is_a: BTO:0001436 ! mycelium

[Term]
id: BTO:0000891
name: NTERA-2 cell
namespace: BrendaTissueOBO
def: "Human embryonal carcinoma (teratocarcinoma). NTERA-2 was cloned from cell line TERA-2 which was derived from a metastatic teratocarcinoma of a 22-year-old Caucasian male." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "NT-2 cell" RELATED []
synonym: "NT2 cell" RELATED []
is_a: BTO:0000306 ! teratocarcinoma cell line
relationship: DRV BTO:0002573 ! TERA-2 cell

[Term]
id: BTO:0000892
name: mycobiont
namespace: BrendaTissueOBO
def: "The fungal component of the lichen partnership, absorbing nutrients and providing structural support for the plant." [Boundary Waters Compendium BWCA Glossary http://www.rook.org/earl/bwca/lists/glossary/]
is_a: BTO:0001494 ! fungus

[Term]
id: BTO:0000893
name: mycorrhiza
namespace: BrendaTissueOBO
def: "The symbiotic association of the mycelium of a fungus with the roots of a seed plant." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=mycorrhiza]
relationship: part_of BTO:0001494 ! fungus

[Term]
id: BTO:0000894
name: myelin
namespace: BrendaTissueOBO
def: "A soft white somewhat fatty material that forms a thick myelin sheath about the protoplasmic core of a myelinated nerve fiber." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=myelin]
relationship: part_of BTO:0000900 ! myelin sheath

[Term]
id: BTO:0000895
name: myelin membrane
namespace: BrendaTissueOBO
def: "The multilamellar myelin membrane is a specisalised lipid-rich domain of the glial cell plasma membrane." [University of Heidelberg \, Neurobiology:http\://server.nbio.uni-heidelberg.de/Groups/WWW_Trotter/Projects.html]
relationship: part_of BTO:0000900 ! myelin sheath

[Term]
id: BTO:0000896
name: bag cell neuron
namespace: BrendaTissueOBO
def: "Cluster of electrically coupled neurons in the abdominal ganglion of Aplysia that are homogeneous, easily dissected out and release peptides that stimulate egg laying." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000022 ! abdominal ganglion

[Term]
id: BTO:0000898
name: myeloma cell
namespace: BrendaTissueOBO
def: "A primary tumor cell of the bone marrow." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=myeloma]
is_a: BTO:0000583 ! bone marrow cancer cell

[Term]
id: BTO:0000899
name: myeloma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000583 ! bone marrow cancer cell
relationship: DRV BTO:0000898 ! myeloma cell

[Term]
id: BTO:0000900
name: myelin sheath
namespace: BrendaTissueOBO
def: "The cylindrical covering on the axons of some neurons; it consists of concentric layers of myelin, formed in the peripheral nervous system by the plasma membrane of Schwann cells, and in the central nervous system by oligodendrocytes. It is interrupted at intervals along its length by gaps known as nodes of Ranvier. Myelin is an electrical insulator that serves to speed the conduction of nerve impulses." [Dorlands Medical Dictionary:MerckSource]
synonym: "medullary sheath" RELATED []
relationship: DRV BTO:0000962 ! oligodendrocyte
relationship: DRV BTO:0001220 ! Schwann cell
relationship: part_of BTO:0000145 ! brain myelin

[Term]
id: BTO:0000901
name: myocardium
namespace: BrendaTissueOBO
def: "The middle and thickest layer of the heart wall, composed of cardiac muscle." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000199 ! cardiac muscle

[Term]
id: BTO:0000902
name: myocyte
namespace: BrendaTissueOBO
def: "A cell of the muscular tissue." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000887 ! muscle

[Term]
id: BTO:0000903
name: atrium
namespace: BrendaTissueOBO
def: "In the heart, the atrium is an upper chamber found on both sides of the heart. The left atrium receives red, oxygenated blood from the lungs by way of the pulmonary veins. The right atrium receives dark red blood from the other parts of the body." [Cardiac and Vascular Health Library:http\://www.saheart.net/library/diction/a.asp]
synonym: "atrial tissue" RELATED []
synonym: "cardiac atrium" RELATED []
relationship: part_of BTO:0000562 ! heart

[Term]
id: BTO:0000904
name: culture condition:beta-aminoisobutyrate-grown cell
namespace: BrendaTissueOBO
synonym: "culture condition:beta-aminoisobutyric acid-grown cell" RELATED []
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000905
name: culture condition:myoinositol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000906
name: myeloid cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001441 ! marrow cell

[Term]
id: BTO:0000907
name: myometrium
namespace: BrendaTissueOBO
def: "The smooth muscle coat of the uterus, which forms the main mass of the organ." [Medical Dictionary Online:http\://www.online-medical-dictionary.org/]
is_a: BTO:0001260 ! smooth muscle
relationship: part_of BTO:0001424 ! uterus

[Term]
id: BTO:0000908
name: myrosin cell
namespace: BrendaTissueOBO
def: "Cell containing glucosinolates (\"mustard oil glucosides\") and myrosinases, enzymes hydrolyzing the glucosinolates. Occur in eleven dicotyledon families, the two largest of which are the Brassicaceae and Euphorbiaceae." [Gramene DB:http\://dev.gramene.org/db/ontology/search/]
synonym: "GRO:0000352" RELATED []
relationship: part_of BTO:0000300 ! cotyledon

[Term]
id: BTO:0000909
name: myxospore
namespace: BrendaTissueOBO
def: "A spore in the fruiting body of a slime mold. " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0001171 ! spore
relationship: part_of BTO:0001291 ! sporophore

[Term]
id: BTO:0000910
name: culture condition:N-acetyl-D-glucosamine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000911
name: culture condition:N-acetyl-D-mannosamine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000912
name: nasal mucosa
namespace: BrendaTissueOBO
def: "The mucosa, or mucous membrane, is a type of tissue that lines the nasal cavity. Mucous membranes are usually moist tissues that are bathed by secretions such as in the nose. " [Medical Encyclopedia:http\://www.nlm.nih.gov/medlineplus/encyclopedia.html]
synonym: "nasal cavity epithelium" RELATED []
is_a: BTO:0000419 ! respiratory epithelium
is_a: BTO:0000973 ! respiratory mucosa
relationship: part_of BTO:0000840 ! nose

[Term]
id: BTO:0000913
name: nasal polyp
namespace: BrendaTissueOBO
def: "Focal accumulations of edema fluid in the mucosa of the nose, with hyperplasia of the associated submucosal connective tissue." [Dorlands Medical Dictionary:MerckSource]
relationship: DRV BTO:0000912 ! nasal mucosa

[Term]
id: BTO:0000914
name: natural killer cell
namespace: BrendaTissueOBO
def: "A large granular lymphocyte capable of killing a tumor or microbial cell without prior exposure to the target cell and without having it presented with or marked by a histocompatibility antigen." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=natural+killer+cell]
synonym: "NK cell" RELATED []
is_a: BTO:0000775 ! lymphocyte

[Term]
id: BTO:0000915
name: nauplius
namespace: BrendaTissueOBO
def: "A crustacean larva in usually the first stage after leaving the egg and with three pairs of appendages, a median eye, and little or no segmentation." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nauplius]
is_a: BTO:0000707 ! larva

[Term]
id: BTO:0000916
name: NC37 cell
namespace: BrendaTissueOBO
def: "Human lymphoblastoid cell line." [Horst Ibelgaufts' COPE Cytokines Online Pathfinder Encyclopaedia:http\://www.copewithcytokines.de/cope.cgi?4459]
is_a: BTO:0000773 ! lymphoblastoid cell line

[Term]
id: BTO:0000917
name: needle
namespace: BrendaTissueOBO
def: "A needle-shaped leaf (as of a conifer)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=needle]
is_a: BTO:0000713 ! leaf

[Term]
id: BTO:0000918
name: nematocyst
namespace: BrendaTissueOBO
def: "One of the stinging organelles of coelenterates used in catching prey." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nematocyst]
is_a: BTO:0001492 ! limb

[Term]
id: BTO:0000919
name: nematode
namespace: BrendaTissueOBO
def: "Any of a phylum (Nematoda or Nemata) of elongated cylindrical worms parasitic in animals or plants or free-living in soil or water." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nematode]
synonym: "roundworm" RELATED []
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0000920
name: neocortex
namespace: BrendaTissueOBO
def: "The newer, six-layered portion of the cerebral cortex, showing stratification and organization characteristic of the most highly evolved type of cerebral tissue." [Dorlands Medical Dictionary:MerckSource]
synonym: "homotypical cortex" RELATED []
synonym: "isocortex" RELATED []
synonym: "neopallium" RELATED []
synonym: "nonolfactory cortex" RELATED []
relationship: part_of BTO:0000233 ! cerebral cortex

[Term]
id: BTO:0000921
name: CAL-27 cell
namespace: BrendaTissueOBO
def: "Human tongue squamous cell carcinoma established from the poorly differentiated squamous cell carcinoma of the tongue removed from a 56-year-old man before treatment in 1982." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "CAL27 cell" RELATED []
is_a: BTO:0003980 ! tongue squamous cell carcinoma cell line

[Term]
id: BTO:0000922
name: neostriatal neuron
namespace: BrendaTissueOBO
relationship: part_of BTO:0000418 ! neostriatum

[Term]
id: BTO:0000923
name: nephridium
namespace: BrendaTissueOBO
def: "A tubular glandular excretory organ characteristic of various invertebrates." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nephridium]
is_a: BTO:0000671 ! kidney

[Term]
id: BTO:0000924
name: nephron
namespace: BrendaTissueOBO
def: "A single excretory unit of the vertebrate kidney." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nephron]
relationship: part_of BTO:0000671 ! kidney

[Term]
id: BTO:0000925
name: nerve
namespace: BrendaTissueOBO
def: "Any of the filamentous bands of nervous tissue that connect parts of the nervous system with the other organs, conduct nervous impulses, and are made up of axons and dendrites together with protective and supportive structures." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nerve]
relationship: part_of BTO:0001484 ! nervous system

[Term]
id: BTO:0000926
name: ophthalmic nerve
namespace: BrendaTissueOBO
def: "The one of the three major branches or divisions of the trigeminal nerve that supply sensory fibers to the lacrimal gland, eyelids, ciliary muscle, nose, forehead, and adjoining parts." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "ophthalmic division" RELATED []
relationship: part_of BTO:0001072 ! trigeminal nerve

[Term]
id: BTO:0000927
name: nerve trunk
namespace: BrendaTissueOBO
def: "The main stem of a nerve, consisting of a bundle of nerve fibers bound together by a tough sheet of connective tissue." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000925 ! nerve

[Term]
id: BTO:0000928
name: limbic system
namespace: BrendaTissueOBO
def: "A group of subcortical structures (as the hypothalamus, the hippocampus, and the amygdala) of the brain that are concerned especially with emotion and motivation." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=limbic+system]
relationship: part_of BTO:0000142 ! brain

[Term]
id: BTO:0000929
name: neural retina
namespace: BrendaTissueOBO
def: "Layer of nerve cells in the retina, embryologically part of the brain. The incoming light passes through nerve-fibres and intermediary nerve cells of the neural retina, before encountering the light-sensitive rods and cones at the interface between neural retina and the pigmented retinal epithelium." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0001175 ! retina

[Term]
id: BTO:0000930
name: neuroblast
namespace: BrendaTissueOBO
def: "Any embryonic cell which develops into a nerve cell or neuron; an immature nerve cell." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000379 ! embryo

[Term]
id: BTO:0000931
name: neuroblastoma cell
namespace: BrendaTissueOBO
def: "Malignant tumour cell derived from primitive ganglion cells. Mainly a tumour of childhood. Commonest sites are adrenal medulla and retroperitoneal tissue. The cells may partially differentiate into cells having the appearance of immature neurons." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "NBL cell" RELATED []
relationship: DRV BTO:0000497 ! ganglion

[Term]
id: BTO:0000932
name: neuroblastoma cell line
namespace: BrendaTissueOBO
synonym: "NBL cell line" RELATED []
relationship: DRV BTO:0000931 ! neuroblastoma cell

[Term]
id: BTO:0000933
name: N18TG2 cell
namespace: BrendaTissueOBO
def: "Mouse neuroblastoma 6-thioguanine resistant mutant of cell line N18 that was established from a mouse of strain A/Jax with neuroblastoma C1300; cells were described to form cAMP in response to prostaglandin E1 and to be aneuploid (modal chromosome number of 81)." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000932 ! neuroblastoma cell line

[Term]
id: BTO:0000934
name: IMR-32 cell
namespace: BrendaTissueOBO
def: "Human neuroblastoma, established from an abdominal mass (diagnosed as neuroblastoma) of a 1-year-old caucasian boy in 1967." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000932 ! neuroblastoma cell line

[Term]
id: BTO:0000935
name: LAN-5 cell
namespace: BrendaTissueOBO
def: "Human neuroblastoma cell line." [PMID:10072300]
synonym: "LAN5 cell" RELATED []
is_a: BTO:0000932 ! neuroblastoma cell line

[Term]
id: BTO:0000936
name: neurofibrillary tangle
namespace: BrendaTissueOBO
def: "Intracellular knot or clump of neurofibrils seen in the cerebral cortex in Alzheimer's disease." [Dorlands Medical Dictionary:MerckSource]
synonym: "neurofilament tangle" RELATED []
is_a: BTO:0000590 ! Alzheimer specific cell type

[Term]
id: BTO:0000937
name: neurohypophysis
namespace: BrendaTissueOBO
def: "The portion of the pituitary gland that is composed of the infundibulum and posterior lobe and is concerned with the secretion of various hormones." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=neurohypophysis]
synonym: "posterior pituitary gland" RELATED []
relationship: part_of BTO:0001073 ! hypophysis

[Term]
id: BTO:0000938
name: neuron
namespace: BrendaTissueOBO
def: "A grayish or reddish granular cell with specialized processes that is the fundamental functional unit of nervous tissue." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=neuron]
synonym: "nerve cell" RELATED []
synonym: "neuronal cell" RELATED []
relationship: DRV BTO:0000930 ! neuroblast
relationship: part_of BTO:0000925 ! nerve
relationship: part_of BTO:0001484 ! nervous system

[Term]
id: BTO:0000939
name: basal cell
namespace: BrendaTissueOBO
def: "One of the innermost cells of the deeper epidermis of the skin." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=basal+cell]
is_a: BTO:0001470 ! epidermal cell

[Term]
id: BTO:0000940
name: juice vesicle
namespace: BrendaTissueOBO
def: "The membranous and fluid-filled cell in a plant." [curators:mgr]
relationship: part_of BTO:0000486 ! fruit

[Term]
id: BTO:0000941
name: CAL-33 cell
namespace: BrendaTissueOBO
def: "Human tongue squamous cell carcinoma established from the surgically removed fragment of a tongue lesion from a 69-year-old man with moderately differentiated squamous cell carcinoma of the tongue in 1983 (prior to therapy)." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0003980 ! tongue squamous cell carcinoma cell line

[Term]
id: BTO:0000942
name: NG-108-15 cell
namespace: BrendaTissueOBO
def: "Neuroblastoma glioma hybrid cell line." [PMID:10550986]
synonym: "NG 108-15 cell" RELATED []
synonym: "NG108-15 cell" RELATED []
is_a: BTO:0000711 ! glioma cell line
is_a: BTO:0000932 ! neuroblastoma cell line

[Term]
id: BTO:0000943
name: culture condition:nicotinic acid-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000944
name: NIH-3T3 cell
namespace: BrendaTissueOBO
def: "Very widely used mouse fibroblast cell line; 3T3 cells have been derived from different mouse strains and it is therefore important to define the particular cell line. NIH strain were from the National Institute of Health in the USA;\nMouse embryonic fibroblast cell line, established from disaggregated Swiss albino mouse embryos in 1962." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ, The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "3T3 cell" RELATED []
synonym: "3T3 fibroblast" RELATED []
synonym: "3T3-Swiss albino cell" RELATED []
synonym: "NIH 3T3 cell" RELATED []
synonym: "NIH/3T3 cell" RELATED []
synonym: "NIH3T3 cell" RELATED []
is_a: BTO:0001958 ! embryonic fibroblast cell line

[Term]
id: BTO:0000945
name: CAL-51 cell
namespace: BrendaTissueOBO
def: "Human breast carcinoma established from the pleural effusion metastasis of a 45-year-old woman with progressive breast adenocarcinoma (after radio-, chemotherapy and surgery) in 1985; rare example of tumor cell line with normal karyotype." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000356 ! breast cancer cell line

[Term]
id: BTO:0000946
name: NT2/D1 cell
namespace: BrendaTissueOBO
def: "Testis; metastatic site: lung malignant pluripotent embryonal carcinoma cell line. The NTERA-2 cl.D1 cell line is a pluripotent human testicular embryonal carcinoma cell line derived by cloning the NTERA-2 cell line." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "NTERA-2 cl.D1 cell" RELATED []
relationship: DRV BTO:0000891 ! NTERA-2 cell

[Term]
id: BTO:0000947
name: neuronal cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000938 ! neuron

[Term]
id: BTO:0000948
name: SKOV-3 cell
namespace: BrendaTissueOBO
def: "Human ovary; metastatic site: ascites adenocarcinoma cell line; established from a 64-year-old caucasian female-" [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "SK-OV-3 cell" RELATED []
synonym: "SKOV3 cell" RELATED []
is_a: BTO:0001882 ! ovary adenocarcinoma cell line

[Term]
id: BTO:0000949
name: Novikoff ascites tumor cell
namespace: BrendaTissueOBO
synonym: "Novikoff ascites hepatoma cell" RELATED []
is_a: BTO:0001330 ! hepatoma ascites cell

[Term]
id: BTO:0000950
name: Novikoff hepatoma cell
namespace: BrendaTissueOBO
def: "Novikoff hepatoma has been induced by feeding 4-dimethylaminoazobenzene to a male rat." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000608 ! hepatoma cell

[Term]
id: BTO:0000951
name: NRK cell
namespace: BrendaTissueOBO
def: "Normal kidney cell line from rattus norvegicus." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000067 ! kidney cell line

[Term]
id: BTO:0000952
name: nuchal ligament
namespace: BrendaTissueOBO
def: "A broad, fibrous, roughly triangular sagittal septum in the back of the neck, separating the right and left sides. It extends from the tips of the spinous processes of all the cervical vertebrae to attach to the entire length of the external occipital crest. Caudally it is continuous with the supraspinous ligament." [Dorlands Medical Dictionary:MerckSource]
synonym: "ligamentum nuchae" RELATED []
relationship: part_of BTO:0000957 ! nape

[Term]
id: BTO:0000953
name: nurse cell
namespace: BrendaTissueOBO
def: "Cells accessory to egg and/or sperm formation in a wide variety of organisms. Usually thought to synthesize special substances and to export these to the developing gamete." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000369 ! egg
relationship: part_of BTO:0001363 ! testis

[Term]
id: BTO:0000954
name: nymph
namespace: BrendaTissueOBO
def: "Any of various immature insects; especially: a larva of an insect (as a grasshopper, true bug, or mayfly) with incomplete metamorphosis that differs from the imago especially in size and in its incompletely developed wings and genitalia." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nymph]
is_a: BTO:0000707 ! larva

[Term]
id: BTO:0000955
name: laryngeal cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001208 ! larynx

[Term]
id: BTO:0000956
name: gut epithelium
namespace: BrendaTissueOBO
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0000545 ! gut

[Term]
id: BTO:0000957
name: nape
namespace: BrendaTissueOBO
def: "The back of the neck." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=nape]
relationship: part_of BTO:0000420 ! neck

[Term]
id: BTO:0000958
name: spermatogonium
namespace: BrendaTissueOBO
def: "An undifferentiated germ cell of a male, originating in a seminiferous tubule and dividing into two primary spermatocytes." [Dorlands Medical Dictionary:MerckSource]
synonym: "spermatophore" RELATED []
synonym: "spermatospore" RELATED []
synonym: "spermospore" RELATED []
is_a: BTO:0000535 ! germ cell
relationship: part_of BTO:0000082 ! male reproductive system

[Term]
id: BTO:0000959
name: esophagus
namespace: BrendaTissueOBO
def: "A muscular tube that in humans is about nine inches (23 centimeters) long and passes from the pharynx down the neck between the trachea and the spinal column and behind the left bronchus where it pierces the diaphragm slightly to the left of the middle line and joins the cardiac end of the stomach." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=esophagus]
synonym: "oesophagus" RELATED []
relationship: part_of BTO:0000058 ! alimentary canal

[Term]
id: BTO:0000960
name: UT-7 cell
namespace: BrendaTissueOBO
def: "Human acute myeloid leukemia established from the bone marrow of a 64-year-old man with acute myeloid leukemia (AML M7) at diagnosis in 1988; cells are constitutively cytokine-dependent and responsive to various cytokines." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0001883 ! acute myeloid leukemia cell line

[Term]
id: BTO:0000961
name: olfactory bulb
namespace: BrendaTissueOBO
def: "A bulbous anterior projection of the olfactory lobe that is the place of termination of the olfactory nerves and is especially well developed in lower vertebrates (as fishes)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=olfactory+bulb]
synonym: "bulbus olfactorius" RELATED []
relationship: part_of BTO:0000928 ! limbic system
relationship: part_of BTO:0001362 ! olfactory lobe

[Term]
id: BTO:0000962
name: oligodendrocyte
namespace: BrendaTissueOBO
def: "One of the cells comprising the oligodendroglia." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "oligodendroglial cell" RELATED []
is_a: BTO:0000771 ! macroglia
relationship: part_of BTO:0000770 ! oligodendroglia

[Term]
id: BTO:0000963
name: oligodendroglioma cell
namespace: BrendaTissueOBO
def: "A rare, slow-growing tumor cell that begins in the oligodendrocytes (brain cells that provide support and nourishment for nerve cells). " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "oligodendroglial tumor cell" RELATED []
relationship: DRV BTO:0000962 ! oligodendrocyte

[Term]
id: BTO:0000964
name: oocyte
namespace: BrendaTissueOBO
def: "An egg before maturation: a female gametocyte." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=oocyte]
is_a: BTO:0000535 ! germ cell
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0000965
name: optic lobe
namespace: BrendaTissueOBO
def: "Either of two prominences of the midbrain concerned with vision." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=optic+lobe]
synonym: "lobus opticus" RELATED []
synonym: "optic tectum" RELATED []
synonym: "superior colliculus" RELATED []
relationship: part_of BTO:0000138 ! midbrain

[Term]
id: BTO:0000966
name: optic nerve
namespace: BrendaTissueOBO
def: "The optic nerve is the nerve that connects the eye to the brain and carries the impulses formed by the retina to the visual cortex of the brain. " [Medical Dictionary:http\://www.medterms.com/]
relationship: part_of BTO:0000439 ! eye

[Term]
id: BTO:0000967
name: osseous plate
namespace: BrendaTissueOBO
synonym: "bony plate" RELATED []
is_a: BTO:0000140 ! bone

[Term]
id: BTO:0000968
name: osteoclast
namespace: BrendaTissueOBO
def: "A large multinucleate cell found in growing bone that resorbs bony tissue, as in the formation of canals and cavities. " [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000140 ! bone
is_a: BTO:0000801 ! macrophage
is_a: BTO:0002050 ! osteogenic cell

[Term]
id: BTO:0000969
name: osteoclastoma cell
namespace: BrendaTissueOBO
def: "An osteolytic tumor cell affecting the metaphyses and epiphyses of long bones, composed of a stroma of spindle cells containing dispersed multinucleate giant cells, and usually being benign but sometimes malignant." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "giant cell myeloma cell" RELATED []
synonym: "giant cell tumor cell" RELATED []
synonym: "giant cell tumor cell of bone" RELATED []
is_a: BTO:0000372 ! bone cancer cell
is_a: BTO:0000898 ! myeloma cell
relationship: DRV BTO:0000968 ! osteoclast

[Term]
id: BTO:0000970
name: osteosarcoma cell
namespace: BrendaTissueOBO
def: "A cell of a sarcoma derived from bone or containing bone tissue." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "osteogenic sarcoma cell" RELATED []
is_a: BTO:0000372 ! bone cancer cell
is_a: BTO:0001207 ! sarcoma cell

[Term]
id: BTO:0000971
name: SAOS-2 cell
namespace: BrendaTissueOBO
def: "Human osteogenic sarcoma, established from the primary osteogenic sarcoma of an 11-year-old Caucasian woman in 1973." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000407 ! osteosarcoma cell line

[Term]
id: BTO:0000972
name: HEP-3B cell
namespace: BrendaTissueOBO
def: "Human hepatocellular carcinoma cell line; established from the tumor tissue of an 8-year-old black boy in 1976; description: cells contain integrated hepatitis B virus genome; cells were described to produce a variety of proteins, e.g. alpha-fetoprotein, albumin, transferrin, alpha2-macroglobulin, alpha1-antitrypsin, haptoglobin and others." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0000973
name: respiratory mucosa
namespace: BrendaTissueOBO
def: "The mucous membrane lining the respiratory tract." [Medical Dictionary Online:http\://www.online-medical-dictionary.org/]
is_a: BTO:0000886 ! mucosa
relationship: part_of BTO:0000203 ! respiratory system

[Term]
id: BTO:0000974
name: culture condition:sulfite-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000975
name: ovary
namespace: BrendaTissueOBO
def: "One of the typically paired essential female reproductive organs that produce eggs and in vertebrates female sex hormones." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ovary]
is_a: BTO:0000254 ! female reproductive gland
is_a: BTO:0003099 ! internal female genital organ
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0000976
name: HEp-2 cell
namespace: BrendaTissueOBO
def: "Human Caucasian larynx carcinoma cell line with HeLa Characteristics." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "Hep2 cell" RELATED []
is_a: BTO:0000955 ! laryngeal cell line

[Term]
id: BTO:0000977
name: ovary cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000975 ! ovary

[Term]
id: BTO:0000978
name: CMK cell
namespace: BrendaTissueOBO
def: "Human acute megakaryocytic leukemia; established from the peripheral blood of a 10-month-old boy with Down's syndrome and acute megakaryocytic leukemia (AML M7) at relapse in 1985." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0001000 ! megakaryocytic leukemia cell line

[Term]
id: BTO:0000979
name: PANC-3 cell
namespace: BrendaTissueOBO
def: "Human pancreas carcinoma cell line." [PMID:11332991]
synonym: "PANC3 cell" RELATED []
is_a: BTO:0000794 ! pancreatic cancer cell line

[Term]
id: BTO:0000980
name: oviduct
namespace: BrendaTissueOBO
def: "A long slender tube that extends from the upper lateral cornu of the uterus to the region of the ovary of the same side; it is attached to the broad ligament by the mesosalpinx, and consists of an ampulla, an infundibulum, an isthmus, two ostia, and a pars uterina." [Dorlands Medical Dictionary:MerckSource]
synonym: "fallopian tube" RELATED []
synonym: "salpinx" RELATED []
synonym: "tuba uterina" RELATED []
synonym: "tuba uterinae" RELATED []
synonym: "uterine tube" RELATED []
is_a: BTO:0003099 ! internal female genital organ
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0000981
name: ovotestis
namespace: BrendaTissueOBO
def: "A hermaphrodite gonad (as in some scale insects)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ovotestis]
is_a: BTO:0000534 ! gonad

[Term]
id: BTO:0000982
name: culture condition:p-cresol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000983
name: culture condition:p-toluate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0000984
name: P-388D1 cell
namespace: BrendaTissueOBO
def: "Lymphoma cell line, established from mus musculus DBA/2. Tumors develop within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 10(7) cells." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "P388D1 cell" RELATED []
is_a: BTO:0000104 ! lymphoma cell line

[Term]
id: BTO:0000985
name: P-815 cell
namespace: BrendaTissueOBO
def: "Mouse mastocytoma, established from the mastocytoma tumor of a DBA/2 mouse treated with methylcolanthrene; used as target cells for cytotoxic T cell assays; as reported cells exhibit no effector activity in an antibody-dependent cell mediated cytotoxic system." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000403 ! mastocytoma cell line

[Term]
id: BTO:0000986
name: pachytene cell
namespace: BrendaTissueOBO
def: "A cell in the third stage of prophase I of meiosis, during which the homologous chromosomes are closely paired and crossing-over takes place." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000845 ! meiotic cell

[Term]
id: BTO:0000987
name: palisade parenchyma
namespace: BrendaTissueOBO
def: "A layer of columnar cells rich in chloroplasts found beneath the upper epidermis of foliage leaves." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=palisade+parenchyma]
synonym: "GRO:0005648" RELATED []
synonym: "palisade layer" RELATED []
synonym: "palisade mesophyll" RELATED []
synonym: "palisade tissue" RELATED []
relationship: part_of BTO:0000718 ! leaf epidermis

[Term]
id: BTO:0000988
name: pancreas
namespace: BrendaTissueOBO
def: "A large lobulated gland of vertebrates that secretes digestive enzymes and the hormones insulin and glucagon." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pancreas]
is_a: BTO:0000345 ! digestive gland
is_a: BTO:0001491 ! viscus

[Term]
id: BTO:0000989
name: taste bud
namespace: BrendaTissueOBO
def: "An end organ mediating the sensation of taste and lying chiefly in the epithelium of the tongue." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=taste+bud]
relationship: part_of BTO:0000992 ! tongue epithelium

[Term]
id: BTO:0000990
name: pancreatic alpha cell
namespace: BrendaTissueOBO
def: "One of the cells in the periphery of the pancreatic islets that secrete somatostatin (alpha1 cells) and glucagon (alpha2 cells)." [Dorlands Medical Dictionary:MerckSource]
synonym: "alpha cell" RELATED []
relationship: part_of BTO:0000991 ! pancreatic islet

[Term]
id: BTO:0000991
name: pancreatic islet
namespace: BrendaTissueOBO
def: "Irregular microscopic structures scattered throughout the pancreas and comprising its endocrine part (the endocrine pancreas). In humans, they are composed of at least four types of cells: the alpha cells, which secrete glucagon; the beta cells, which are the most abundant and secrete insulin; the delta cells, which secrete somatostatin; and the PP cells, which secrete pancreatic polypeptide. Degeneration of the beta cells, whose secretion (insulin) is important in carbohydrate metabolism, is the major cause of type I diabetes mellitus. " [Dorlands Medical Dictionary:MerckSource]
synonym: "island of Langerhans" RELATED []
synonym: "island of pancreas" RELATED []
relationship: part_of BTO:0000650 ! endocrine pancreas

[Term]
id: BTO:0000992
name: tongue epithelium
namespace: BrendaTissueOBO
synonym: "lingual epithelium" RELATED []
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0001385 ! tongue

[Term]
id: BTO:0000993
name: paneth cell
namespace: BrendaTissueOBO
def: "Paneth cell: Coarsely granular secretory cells found in the basal regions of crypts in the small intestine." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000305 ! crypt

[Term]
id: BTO:0000994
name: RBL-1 cell
namespace: BrendaTissueOBO
def: "Rat basophilic leukemia; this rat basophilic leukemia (RBL) cell line was established from chlorethylamine-treated rats." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0001018 ! basophilic leukemia cell line

[Term]
id: BTO:0000995
name: paramyeloblast
namespace: BrendaTissueOBO
def: "Myeloblast: a large mononuclear nongranular bone-marrow cell; especially: one that is a precursor of a myelocyte." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=paramyeloblast]
comment: Paramyeloblast : pathologische Form eines Myeloblasten mit Zeichen der malignen Entdifferenzierung. Paramyeloblasten kommen im Rahmen myeloischer Leukämien v.a. akuter Leukämieformen vor. Sie sind meist undifferenziert und nur mit zytochemischen Reaktionen oder Nachweis von Auer-Körpern zu identifizieren.
is_a: BTO:0000583 ! bone marrow cancer cell
relationship: DRV BTO:0000187 ! myeloblast

[Term]
id: BTO:0000996
name: gametocyte
namespace: BrendaTissueOBO
def: "A cell from which gametes develop by meiotic division, especially a spermatocyte or an oocyte." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000081 ! reproductive system

[Term]
id: BTO:0000997
name: parathyroid gland
namespace: BrendaTissueOBO
def: "Any of usually four small endocrine glands that are adjacent to or embedded in the thyroid gland and produce parathyroid hormone." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=parathyroid+gland]
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0000828 ! throat
relationship: part_of BTO:0001379 ! thyroid gland

[Term]
id: BTO:0000998
name: paraveinal mesophyll
namespace: BrendaTissueOBO
def: "Layer of cells at phloem between spongy & palisade parenchyma. Protein builds up in this layer." [University of Central Oklahoma \, Department of Biology:Plant Anatomy \, Lecture 23 \, Leaf Structure]
is_a: BTO:0000858 ! mesophyll

[Term]
id: BTO:0000999
name: parenchyma
namespace: BrendaTissueOBO
def: "A tissue of higher plants that consists of thin-walled living photosynthetic or storage cells capable of division even when mature and that makes up much of the substance of leaves and roots, the pulp of fruits, and parts of stems and supporting structures." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=parenchyma]
synonym: "GRO:0005421" RELATED []
is_a: BTO:0001310 ! storage tissue
relationship: part_of BTO:0000486 ! fruit
relationship: part_of BTO:0000713 ! leaf
relationship: part_of BTO:0001188 ! root
relationship: part_of BTO:0001300 ! stem
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0001000
name: megakaryocytic leukemia cell line
namespace: BrendaTissueOBO
is_a: BTO:0000737 ! leukemia cell line
is_a: BTO:0001549 ! megakaryocytic cell line

[Term]
id: BTO:0001001
name: parietal lobe
namespace: BrendaTissueOBO
def: "The upper central lobe of the cerebral hemisphere, separated from the temporal lobe below by the lateral sulcus, but continuous at the posterior end of that sulcus, and separated from the frontal lobe by the central sulcus. Behind, it is continuous with the occipital lobe on the lateral surface, but separated from it by the parietooccipital sulcus on the medial surface." [Dorlands Medical Dictionary:MerckSource]
synonym: "parietal cortex" RELATED []
relationship: part_of BTO:0000445 ! cerebral lobe

[Term]
id: BTO:0001002
name: schizont
namespace: BrendaTissueOBO
def: "A multinucleate sporozoan (as a malaria parasite) that reproduces by schizogony." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "agamont" RELATED []
is_a: BTO:0000749 ! sporozoan

[Term]
id: BTO:0001003
name: parotid acinar cell
namespace: BrendaTissueOBO
is_a: BTO:0000433 ! exocrine acinar cell
relationship: part_of BTO:0001004 ! parotid gland

[Term]
id: BTO:0001004
name: parotid gland
namespace: BrendaTissueOBO
def: "Either of a pair of large serous salivary glands situated below and in front of the ear." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=parotid+gland]
is_a: BTO:0001203 ! salivary gland
relationship: part_of BTO:0000368 ! ear

[Term]
id: BTO:0001006
name: pelvis
namespace: BrendaTissueOBO
def: "The inferior portion of the trunk of the body, bounded anteriorly and laterally by the two hip bones and posteriorly by the sacrum and coccyx. The pelvis is divided by a plane passing through the terminal lines into the p. major superiorly and the p. minor inferiorly." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0001493 ! trunk

[Term]
id: BTO:0001007
name: AGS cell
namespace: BrendaTissueOBO
def: "Human Caucasian gastric adenocarcinoma cell line." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0002380 ! gastric adenocarcinoma cell line

[Term]
id: BTO:0001008
name: PBMC cell line
namespace: BrendaTissueOBO
synonym: "peripheral blood mononuclear cell cell line" RELATED []
is_a: BTO:0001035 ! hematopoietic cell line
relationship: DRV BTO:0001025 ! peripheral blood mononuclear cell

[Term]
id: BTO:0001009
name: PC-12 cell
namespace: BrendaTissueOBO
def: "Rat adrenal pheochromocytoma established from a transplantable rat adrenal pheochromocytoma in 1976; cells were described to synthesize catecholamines (dopamine, norepinephrine); in response to nerve growth factor (NGF) a neuronal phenotype could be induced reversibly." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "PC12 cell" RELATED []
is_a: BTO:0000201 ! pheochromocytoma cell line

[Term]
id: BTO:0001010
name: callus
namespace: BrendaTissueOBO
def: "Undifferentiated tissue that develops on or around an injured or cut plant surface or in tissue culture." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000720 ! plant form

[Term]
id: BTO:0001011
name: cerebellar Purkinje cell
namespace: BrendaTissueOBO
def: "Large neurons in the cerebellar cortex that have piriform cell bodies in the Purkinje layer (the stratum purkinjense cerebelli) and large branching dendrite trees going through the outer (molecular) layer towards the surface. " [Dorlands Medical Dictionary:MerckSource]
synonym: "Purkinje cell" RELATED []
synonym: "Purkinje neuron" RELATED []
is_a: BTO:0000938 ! neuron
relationship: part_of BTO:0000043 ! cerebellar cortex

[Term]
id: BTO:0001012
name: pedal ganglion
namespace: BrendaTissueOBO
def: "The pedal ganglia mainly are necessary for coordination of locomotion of a snail." [:Biology, :Czihak, :Langer, :Ziegler, Snails Nervous System:1992]
is_a: BTO:0000497 ! ganglion
relationship: part_of BTO:0001448 ! visceral hump

[Term]
id: BTO:0001013
name: pedal muscle
namespace: BrendaTissueOBO
def: "The foot retractor or protractor muscle of a shell." [curators:mgr]
is_a: BTO:0001262 ! soft body part
relationship: part_of BTO:0001266 ! invertebrate muscular system

[Term]
id: BTO:0001014
name: Mo-T cell
namespace: BrendaTissueOBO
def: "Human hairy cell leukemia T-lymphocyte cell line." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "Mo cell" RELATED []
synonym: "Mo T cell" RELATED []
is_a: BTO:0003681 ! hairy cell leukemia cell line
created_by: Marion
creation_date: 2008-11-04T11:21:32Z

[Term]
id: BTO:0001015
name: culture condition:pentanoate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001016
name: pericardial fluid
namespace: BrendaTissueOBO
def: "A fluid found in small amounts in the potential space between the parietal and visceral laminae of the serous pericardium." [Dorlands Medical Dictionary:MerckSource]
relationship: DRV BTO:0000717 ! pericardium

[Term]
id: BTO:0001017
name: pericarp
namespace: BrendaTissueOBO
def: "The ripened and variously modified walls of a plant ovary." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pericarp]
synonym: "GRO:0005247" RELATED []
relationship: part_of BTO:0000486 ! fruit

[Term]
id: BTO:0001018
name: basophilic leukemia cell line
namespace: BrendaTissueOBO
is_a: BTO:0000737 ! leukemia cell line

[Term]
id: BTO:0001019
name: prostate gland cell line
namespace: BrendaTissueOBO
synonym: "prostate cell line" RELATED []
relationship: DRV BTO:0001129 ! prostate gland

[Term]
id: BTO:0001020
name: periodontal ligament
namespace: BrendaTissueOBO
def: "The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket." [Dorlands Medical Dictionary:MerckSource]
synonym: "alveolar periosteum" RELATED []
synonym: "alveolodental ligament" RELATED []
synonym: "alveolodental membrane" RELATED []
synonym: "desmodontium" RELATED []
synonym: "odontoperiosteum" RELATED []
synonym: "paradentium" RELATED []
synonym: "peridental membrane" RELATED []
synonym: "peridontal membrane" RELATED []
synonym: "peridontium" RELATED []
relationship: part_of BTO:0001021 ! periodontium

[Term]
id: BTO:0001021
name: periodontium
namespace: BrendaTissueOBO
def: "The tissues that invest or help to invest and support the teeth, including the periodontal ligament, gingivae, cementum, and alveolar and supporting bone." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000397 ! tooth

[Term]
id: BTO:0001022
name: periosteum
namespace: BrendaTissueOBO
def: "The dense fibrous membrane covering the surface of bones except at the joints and serving as an attachment for muscles and tendons." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000140 ! bone

[Term]
id: BTO:0001023
name: ovary cancer cell
namespace: BrendaTissueOBO
def: "A malignant tumor cell of the ovary." [Aristoteles University of Thessaloniki \, Dictionary of Medical Terms:http\://www.med.auth.gr/db/dictionary1/gr/]
synonym: "ovarian cancer cell" RELATED []
synonym: "ovarian carcinoma cell" RELATED []
relationship: DRV BTO:0000975 ! ovary

[Term]
id: BTO:0001024
name: retinal rod
namespace: BrendaTissueOBO
def: "Major photoreceptor cell of vertebrate retina (about 125 million in a human eye). Columnar cells having three distinct regions: a region adjacent to, and synapsed with, the neural layer of the retina contains the nucleus and other cytoplasmic organelles, below this is the inner segment, rich in mitochondria, that is connected through a thin neck (in which is located a ciliary body) to the outer segment. The outer segment largely consists of a stack of discs (membrane infoldings that are incompletely separated in cones) that are continually replenished near the inner segment and that are shed from the distal end and phagocytosed by the pigmented epithelium. The membranes of the discs are rich in rhodopsin, the pigment that absorbs light." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0001060 ! photoreceptor

[Term]
id: BTO:0001025
name: peripheral blood mononuclear cell
namespace: BrendaTissueOBO
def: "A mixture of monocytes and lymphocytes; blood leucocytes from which granulocytes have been separated and removed." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "PBM cell" RELATED []
synonym: "PBMC" RELATED []
synonym: "PBMC cell" RELATED []
is_a: BTO:0000878 ! mononuclear cell
relationship: part_of BTO:0000553 ! peripheral blood

[Term]
id: BTO:0001026
name: polymorphonuclear leukocyte
namespace: BrendaTissueOBO
def: "Any fully developed granular leukocyte whose nucleus contains multiple lobes joined by filamentous connections, especially a neutrophil." [Dorlands Medical Dictionary:MerckSource]
synonym: "PML" RELATED []
is_a: BTO:0000130 ! neutrophil
is_a: BTO:0001441 ! marrow cell

[Term]
id: BTO:0001027
name: peripheral nerve
namespace: BrendaTissueOBO
def: "The peripheral nerves include the 12 cranial nerves, the spinal nerves and roots, and what are called the autonomic nerves that are concerned specifically with the regulation of the heart muscle, the muscles in blood vessel walls, and glands. " [Medical Dictionary:http\://www.medterms.com/]
relationship: part_of BTO:0001028 ! peripheral nervous system

[Term]
id: BTO:0001028
name: peripheral nervous system
namespace: BrendaTissueOBO
def: "The peripheral nervous system (PNS) connects the central nervous system (CNS) to sensory organs (such as the eye and ear), other organs of the body, muscles, blood vessels and glands. " [Medical Dictionary:http\://www.medterms.com/]
synonym: "PNS" RELATED []
relationship: part_of BTO:0001484 ! nervous system

[Term]
id: BTO:0001029
name: perisperm
namespace: BrendaTissueOBO
def: "The nutritive tissue that is derived from the nucleus and surrounds the embryo of the seed." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0001226 ! seed

[Term]
id: BTO:0001030
name: J774.2 cell
namespace: BrendaTissueOBO
def: "Mouse, BALB/c, blood, not defined tumor cell line. Recloned from J774.1 original ascites and solid tumour. Produces IL-1." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0002279 ! J-774 cell

[Term]
id: BTO:0001031
name: peritoneal fluid
namespace: BrendaTissueOBO
def: "A liquid that is made in the abdominal cavity to lubricate the surface of the tissue that lines the abdominal wall and pelvic cavity and covers most of the organs in the abdomen." [Dictionary of Cancer Terms:http\://www.cancer.gov/]
relationship: part_of BTO:0001472 ! peritoneum

[Term]
id: BTO:0001032
name: cardiac Purkinje cell
namespace: BrendaTissueOBO
def: "Cells of the Purkinje fibers of the heart; they are large, clear, tightly packed cells with many gap junctions between them and thus conduct impulses rapidly." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0001735 ! cardiac Purkinje fiber

[Term]
id: BTO:0001033
name: prostate cancer cell line
namespace: BrendaTissueOBO
synonym: "CaP cell" RELATED []
synonym: "CaP cell line" RELATED []
is_a: BTO:0001019 ! prostate gland cell line

[Term]
id: BTO:0001034
name: peritoneal macrophage
namespace: BrendaTissueOBO
def: "Macrophage found in peritoneum and that can be obtained by lavage." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000801 ! macrophage

[Term]
id: BTO:0001035
name: hematopoietic cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000574 ! hematopoietic cell

[Term]
id: BTO:0001036
name: retinal cone
namespace: BrendaTissueOBO
def: "The other light-sensitive cell type of the retina, that, unlike retinal rods, is differentially sensitive to particular wavelengths of light, and is important for colour vision. There are three types of cones, each type sensitive to red, green or blue. Present in large numbers in the fovea." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "cone cell" RELATED []
is_a: BTO:0001060 ! photoreceptor

[Term]
id: BTO:0001037
name: sensory cell
namespace: BrendaTissueOBO
def: "1:  A peripheral nerve cell (as an olfactory cell) located at a sensory receiving surface and being the primary receptor of a sensory impulse.  \n2:  A nerve cell (as a spinal ganglion cell) transmitting sensory impulses . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000938 ! neuron
relationship: part_of BTO:0001027 ! peripheral nerve

[Term]
id: BTO:0001038
name: peritrophic membrane
namespace: BrendaTissueOBO
def: "A delicate, cylindrical sheath of chitin continuously secreted from the posterior edge of the foregut of insects and millipedes that ingest solid food, which surrounds the food as it passes through the midgut." [Dorlands Medical Dictionary:MerckSource]
relationship: REL BTO:0000507 ! foregut

[Term]
id: BTO:0001039
name: peritubular cell
namespace: BrendaTissueOBO
def: "Seminiferous tubules are made up of Sertoli cells and germ cells, and they are surrounded by peritubular and myoid cells. " [eMedicine \, Rubenstein J. \, Male Infertility:http\://www.emedicine.com/med/topic1167.htm]
relationship: part_of BTO:0001235 ! seminiferous tubule

[Term]
id: BTO:0001040
name: petal
namespace: BrendaTissueOBO
def: "The often showy flower component attached just inside the sepals; petals are usually colorful to attract pollinators." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005667" RELATED []
relationship: part_of BTO:0000163 ! corolla

[Term]
id: BTO:0001041
name: petiole
namespace: BrendaTissueOBO
def: "A slender stem that supports the blade of a foliage leaf." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=petiole]
synonym: "GRO:0005085" RELATED []
relationship: part_of BTO:0000713 ! leaf

[Term]
id: BTO:0001042
name: amygdala
namespace: BrendaTissueOBO
def: "The one of the four basal ganglia in each cerebral hemisphere that is part of the limbic system and consists of an almond-shaped mass of gray matter in the anterior extremity of the temporal lobe." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=amygdala]
synonym: "amygdaloid body" RELATED []
synonym: "amygdaloid complex" RELATED []
synonym: "amygdaloid nucleus" RELATED []
synonym: "archistriatum" RELATED []
synonym: "corpus amygdaloideum" RELATED []
synonym: "nucleus amygdalae" RELATED []
is_a: BTO:0000235 ! basal ganglion
relationship: part_of BTO:0000928 ! limbic system
relationship: part_of BTO:0001355 ! temporal lobe
relationship: part_of BTO:0003399 ! avian pallium

[Term]
id: BTO:0001043
name: adult
namespace: BrendaTissueOBO
def: "Fully developed and mature: GROWN-UP." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=adult]
synonym: "adult stage" RELATED []
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0001044
name: phagocyte
namespace: BrendaTissueOBO
def: "A cell (as a white blood cell) that engulfs and consumes foreign material (as microorganisms) and debris." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=phagocyte]
is_a: BTO:0000574 ! hematopoietic cell

[Term]
id: BTO:0001045
name: T-lymphocyte cell line
namespace: BrendaTissueOBO
synonym: "T-cell line" RELATED []
is_a: BTO:0001008 ! PBMC cell line
relationship: DRV BTO:0000782 ! T-lymphocyte

[Term]
id: BTO:0001046
name: pharate pupa
namespace: BrendaTissueOBO
def: "Pupa of an insect, having its new cuticle formed beneath its present cuticle, and thus ready for its next moult. " [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0001143 ! pupa

[Term]
id: BTO:0001047
name: pharyngeal mucosa
namespace: BrendaTissueOBO
is_a: BTO:0000886 ! mucosa
relationship: part_of BTO:0001049 ! pharynx

[Term]
id: BTO:0001048
name: pharyngeal muscle
namespace: BrendaTissueOBO
def: "The muscular coat of the pharynx, consisting of The three constrictor muscles and the stylopharyngeal, salpingopharyngeal, and palatopharyngeal muscles." [Dorlands Medical Dictionary:MerckSource]
synonym: "musculus pharyngis" RELATED []
is_a: BTO:0000021 ! head muscle
relationship: part_of BTO:0001049 ! pharynx

[Term]
id: BTO:0001049
name: pharynx
namespace: BrendaTissueOBO
def: "The part of the vertebrate alimentary canal between the cavity of the mouth and the esophagus.\nThe pharynx of Nematodes is an efficient pump and forces food into the intestines." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pharynx, The Phylum Nematoda:http\://www.earthlife.net/inverts/nematoda.html]
relationship: part_of BTO:0000058 ! alimentary canal
relationship: part_of BTO:0001090 ! mouth

[Term]
id: BTO:0001050
name: culture condition:phenol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001051
name: culture condition:phenylacetic acid-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001052
name: ND-1 cell
namespace: BrendaTissueOBO
def: "Prostate carcinoma cell line." [PMID:12067994]
synonym: "ND1 cell" RELATED []
is_a: BTO:0001033 ! prostate cancer cell line

[Term]
id: BTO:0001053
name: culture condition:phenylglyoxylate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001054
name: pheochromocytoma cell
namespace: BrendaTissueOBO
def: "Pheochromocytoma is a rare tumor that arises from tissue in the adrenal gland. The tumor increases production of adrenaline and noradrenaline, which raises blood pressure and heart rate." [Mayoclinic.com:http\://www.mayoclinic.com]
is_a: BTO:0000592 ! adrenal gland cancer cell

[Term]
id: BTO:0001055
name: vulva
namespace: BrendaTissueOBO
def: "The external female genital organs, including the clitoris, vaginal lips, and the opening to the vagina. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0001056
name: myelocytic leukemia cell
namespace: BrendaTissueOBO
def: "Myeloid leukemia is a disease in which cancer (malignant) cells are found in the blood and bone marrow. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "myeloid leukemia cell" RELATED []
is_a: BTO:0001271 ! leukemia cell

[Term]
id: BTO:0001057
name: neural tube
namespace: BrendaTissueOBO
def: "A dorsal tubular structure in the vertebrate embryo formed by longitudinal folding of the neural plate and differentiating into the brain and spinal cord." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: DRV BTO:0001765 ! neural plate

[Term]
id: BTO:0001058
name: phloem
namespace: BrendaTissueOBO
def: "A complex tissue in the vascular system of higher plants that consists mainly of sieve tubes and elongated parenchyma cells usually with fibers and that functions in translocation and in support and storage." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=phloem]
synonym: "GRO:0005417" RELATED []
relationship: DRV BTO:0000310 ! protophloem
relationship: part_of BTO:0001299 ! stele

[Term]
id: BTO:0001059
name: culture condition:phosphonoacetate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001060
name: photoreceptor
namespace: BrendaTissueOBO
def: "A specialized cell type in a multicellular organism that is sensitive to light. This definition excludes single-celled organisms, but includes non-eye receptors, such as snake infra-red (heat) detectors or photosensitive pineal gland cells." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "photoreceptor cell" RELATED []
relationship: part_of BTO:0001175 ! retina

[Term]
id: BTO:0001061
name: PC-3 cell
namespace: BrendaTissueOBO
def: "Human prostate carcinoma cell line; established from the bone marrow metastasis isolated post-mortem from a 62-year-old Caucasian man with grade IV prostate cancer (poorly differentiated adenocarcinoma) after androgen suppression therapy; described to form tumors in nude mice, to grow in soft agar, and to be unresponsive to androgen treatment." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "PC3 cell" RELATED []
is_a: BTO:0001033 ! prostate cancer cell line

[Term]
id: BTO:0001062
name: PPC-1 cell
namespace: BrendaTissueOBO
def: "Human prostate cancer cell line." [PMID:12700285]
is_a: BTO:0001033 ! prostate cancer cell line

[Term]
id: BTO:0001063
name: phrenic nerve
namespace: BrendaTissueOBO
def: "A general motor and sensory nerve on each side of the body that arises chiefly from the fourth cervical nerve, passes down through the thorax to the diaphragm, and supplies or gives off branches supplying especially the pericardium, pleura, and diaphragm." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "diaphragmatic nerve" RELATED []
synonym: "nervus phrenicus" RELATED []
synonym: "phrenic" RELATED []
is_a: BTO:0000925 ! nerve

[Term]
id: BTO:0001064
name: phycobiont
namespace: BrendaTissueOBO
def: "Phycobionts are usually green algae (Chlorophyceae), yellow-green algae (Xanthophyceae), and some other groups of algae." [University of Hamburg \, Faculty of Biology:http\://www.biologie.uni-hamburg.de/b-online/e33/33a.htm]
is_a: BTO:0000720 ! plant form

[Term]
id: BTO:0001065
name: Tsu-Pr1 cell
namespace: BrendaTissueOBO
def: "Human prostate epithelial carcinoma cell line." [PMID:12810698]
is_a: BTO:0001033 ! prostate cancer cell line

[Term]
id: BTO:0001066
name: hippocampal pyramidal layer
namespace: BrendaTissueOBO
def: "A well-defined double layer of pyramidal cells in the hippocampus; their dendrites extend from the stratum oriens to the stratum moleculare." [Dorlands Medical Dictionary:MerckSource]
synonym: "stratum pyramidale hippocampi" RELATED []
relationship: part_of BTO:0000601 ! hippocampus

[Term]
id: BTO:0001067
name: pineal gland
namespace: BrendaTissueOBO
def: "A small, cone-shaped organ in the brain of most vertebrates that secretes the hormone melatonin. " [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "epiphysis cerebri" RELATED []
synonym: "pineal body" RELATED []
synonym: "pineal organ" RELATED []
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0000175 ! epithalamus

[Term]
id: BTO:0001068
name: pinealocyte
namespace: BrendaTissueOBO
def: "The parenchymatous epithelioid cell of the pineal gland that has prominent nucleoli and long processes ending in bulbous expansions. " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "chief cell" RELATED []
synonym: "pineal cell" RELATED []
relationship: part_of BTO:0001067 ! pineal gland

[Term]
id: BTO:0001069
name: pitcher
namespace: BrendaTissueOBO
def: "A modified leaf of a pitcher plant in which the hollowed petiole and base of the blade form an elongated receptacle." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pitcher]
is_a: BTO:0000713 ! leaf

[Term]
id: BTO:0001070
name: pitcher secretion
namespace: BrendaTissueOBO
relationship: DRV BTO:0001069 ! pitcher

[Term]
id: BTO:0001071
name: pith
namespace: BrendaTissueOBO
def: "A usually continuous central strand of spongy tissue in the stems of most vascular plants that probably functions chiefly in storage." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pith]
relationship: part_of BTO:0001299 ! stele

[Term]
id: BTO:0001072
name: trigeminal nerve
namespace: BrendaTissueOBO
def: "Either of the fifth pair of cranial nerves, having sensory and motor functions in the face, teeth, mouth, and nasal cavity. " [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "trigeminus" RELATED []
is_a: BTO:0001104 ! cranial nerve

[Term]
id: BTO:0001073
name: hypophysis
namespace: BrendaTissueOBO
def: "A small oval endocrine organ that is attached to the infundibulum of the brain, consists of an epithelial anterior lobe joined by an intermediate part to a posterior lobe of nervous origin, and produces various internal secretions directly or indirectly impinging on most basic body functions." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=hypophysis]
synonym: "pituitary body" RELATED []
synonym: "pituitary gland" RELATED []
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0000232 ! cerebellum

[Term]
id: BTO:0001074
name: trigeminal nucleus
namespace: BrendaTissueOBO
def: "One of the nuclei of the trigeminal nerve, consisting of a slender column of cells in the lateral central gray matter of the superior part of the fourth ventral and cerebral aqueduct. It is the only central nervous system site of primary sensory neurons; its cells resemble posterior root ganglion cells. The peripheral processes of the cells, which form the mesencephalic tract, carry proprioceptive impulses; the central processes have widespread cerebellar and brain stem connections, including the motor nucleus of the trigeminal nerve. " [Dorlands Medical Dictionary:MerckSource]
synonym: "mesencephalic nucleus of trigeminal nerve" RELATED []
synonym: "nucleus mesencephalicus nervi trigemini" RELATED []
synonym: "nucleus mesencephalicus trigeminalis" RELATED []
synonym: "nucleus tractus mesencephali nervi trigeminalis" RELATED []
relationship: part_of BTO:0001072 ! trigeminal nerve

[Term]
id: BTO:0001075
name: motor trigeminal nucleus
namespace: BrendaTissueOBO
is_a: BTO:0001074 ! trigeminal nucleus

[Term]
id: BTO:0001076
name: pituitary gland tumor cell
namespace: BrendaTissueOBO
def: "A benign tumor of the pituitary, the master gland that controls other glands and influences numerous body functions including growth. Although the tumor itself is not cancerous, it may affect pituitary function, and therefore may need to be removed." [Medical Dictionary:http\://www.medterms.com/]
synonym: "pituitary adenoma cell" RELATED []
synonym: "pituitary tumor cell" RELATED []
relationship: DRV BTO:0001073 ! hypophysis

[Term]
id: BTO:0001077
name: AtT-20 cell
namespace: BrendaTissueOBO
def: "Mouse pituitary tumor cell line. Morphology: small rounded cells." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000756 ! pituitary gland tumor cell line

[Term]
id: BTO:0001078
name: placenta
namespace: BrendaTissueOBO
def: "The vascular organ in mammals except monotremes and marsupials that unites the fetus to the maternal uterus and mediates its metabolic exchanges through a more or less intimate association of uterine mucosal with chorionic and usually allantoic tissues; also: an analogous organ in another animal." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=placenta]
relationship: part_of BTO:0000083 ! female reproductive system
relationship: part_of BTO:0000449 ! fetus

[Term]
id: BTO:0001079
name: trophoblast
namespace: BrendaTissueOBO
def: "A thin layer of ectoderm that forms the wall of many mammalian blastulas and functions in the nutrition and implantation of the embryo." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=trophoblast]
synonym: "trophoderm" RELATED []
relationship: part_of BTO:0000128 ! blastula

[Term]
id: BTO:0001080
name: Morris hepatoma cell
namespace: BrendaTissueOBO
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0001081
name: MOLT-3 cell
namespace: BrendaTissueOBO
def: "Human T cell leukemia cell line; established from the peripheral blood of a 19-year-old man with acute lymphoblastic leukemia (ALL) in relapse in 1971; sister cell line of MOLT-4." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0002144 ! acute lymphoblastic leukemia cell line
is_a: BTO:0002504 ! T-lymphoblastic leukemia cell line

[Term]
id: BTO:0001082
name: MM46 cell
namespace: BrendaTissueOBO
def: "Mouse mammary carcinoma cell line." [PMID:11862417]
is_a: BTO:0000356 ! breast cancer cell line

[Term]
id: BTO:0001083
name: MH134 cell
namespace: BrendaTissueOBO
def: "Mouse hepatoma cell line." [PMID:12529995]
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0001084
name: plantlet
namespace: BrendaTissueOBO
def: "A small or young plant." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=plantlet]
is_a: BTO:0000720 ! plant form

[Term]
id: BTO:0001085
name: vascular system
namespace: BrendaTissueOBO
def: "The vessels of the body, especially the blood vessels." [Nephrogenic Diabetes Insipidus Foundation \, NDI Terminology:http\://www.ndif.org/Terms/]
relationship: part_of BTO:0000088 ! cardiovascular system

[Term]
id: BTO:0001086
name: embryonic stem cell
namespace: BrendaTissueOBO
def: "Totipotent cell cultured from early embryo. Have the advantage that following modification in vitrothey can be used to produce chimeric embryos and thus transgenic animals." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "ES cell" RELATED []
relationship: part_of BTO:0000379 ! embryo

[Term]
id: BTO:0001087
name: plasmacytoma cell
namespace: BrendaTissueOBO
def: "Cancer cell of the plasma cells (white blood cells that produce antibodies) that may turn into multiple myeloma. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "plasma cell tumor cell" RELATED []
synonym: "plasmocytoma cell" RELATED []
is_a: BTO:0000580 ! blood cancer cell

[Term]
id: BTO:0001088
name: gastric cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001307 ! stomach

[Term]
id: BTO:0001089
name: MPC-11 cell
namespace: BrendaTissueOBO
def: "Tissue: Mouse BALB/c B-lymphocyte, plasmacytoma, myeloma. Morphology: lymphoblast. MPC-11 cells have been reported to produce murine IL-6." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
comment: Plasmacytoma cell line.
is_a: BTO:0000456 ! plasmacytoma cell line

[Term]
id: BTO:0001090
name: mouth
namespace: BrendaTissueOBO
def: "The natural opening through which food passes into the body of an animal and which in vertebrates is typically bounded externally by the lips and internally by the pharynx and encloses the tongue, gums, and teeth." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=mouth]
synonym: "oral cavity" RELATED []
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0001091
name: axenic culture
namespace: BrendaTissueOBO
def: "A situation in which only one species is present. Thus an axenic culture is uncontaminated by organisms of other species, an axenic organism does not have commensal organisms in the gut etc. Some organisms have obligate symbionts and cannot be grown axenically." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000214 ! cell culture

[Term]
id: BTO:0001092
name: KATO-III cell
namespace: BrendaTissueOBO
def: "Species: human, Mongoloid male 55-year-old; Tissue: stomach; Tumor: carcinoma." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "KATO III cell" RELATED []
is_a: BTO:0000787 ! gastric cancer cell line

[Term]
id: BTO:0001093
name: WEHI-231 cell
namespace: BrendaTissueOBO
def: "Mouse, (BALB/cxNZB) F1, lymphoblastic lymphoma cell line. Morphology: Lymphoblast Mouse B cell lymphoma." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0001518 ! B-lymphoma cell line

[Term]
id: BTO:0001094
name: pre-B acute lymphoblastic leukemia cell
namespace: BrendaTissueOBO
alt_id: BTO:0001555
def: "The most common subtype, consisting of small uniform lymphoblasts that do not synthesize complete functional immunoglobulins. The term has sometimes been restricted to the minority of the larger group that synthesize heavy chains of immunoglobulins." [Dorlands Medical Dictionary:MerckSource]
synonym: "acute lymphoblastic leukemia cell, pre-B-cell type" RELATED []
synonym: "pre-B leukemia cell" RELATED []
is_a: BTO:0000731 ! acute lymphoblastic leukemia cell
is_a: BTO:0001271 ! leukemia cell

[Term]
id: BTO:0001095
name: pod
namespace: BrendaTissueOBO
def: "A dry dehiscent pericarp or fruit that is composed of one or more carpels; especially: legume" [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pod]
synonym: "cod" RELATED []
synonym: "seedcase" RELATED []
is_a: BTO:0000609 ! husk
is_a: BTO:0001017 ! pericarp

[Term]
id: BTO:0001096
name: lymphoid cell
namespace: BrendaTissueOBO
def: "Any of the cells responsible for the production of immunity mediated by cells or antibodies and including lymphocytes, lymphoblasts, and plasma cells. Cells derived from stem cells of the lymphoid lineage: large and small lymphocytes, plasma cells." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/, The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0000753 ! lymphoid tissue

[Term]
id: BTO:0001097
name: pollen
namespace: BrendaTissueOBO
def: "The structure into which a haploid microspore develops; contains a halpoid tube nucleus and two haploid sperm nuclei at maturity." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005650" RELATED []
synonym: "pollen grain" RELATED []
relationship: DRV BTO:0000124 ! microspore
relationship: DRV BTO:0001778 ! microsporangium

[Term]
id: BTO:0001098
name: sorocarp
namespace: BrendaTissueOBO
def: "Fruiting body formed by some cellular slime moulds; has both stalk and spore-mass." [The Dictionary of Cell and Molecular Biology:Third Edition]
is_a: BTO:0000487 ! fruitbody

[Term]
id: BTO:0001099
name: blastocyst
namespace: BrendaTissueOBO
def: "The modified blastula of a placental mammal." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=blastocyst]
is_a: BTO:0000128 ! blastula

[Term]
id: BTO:0001100
name: B-cell acute lymphoblastic leukemia cell
namespace: BrendaTissueOBO
def: "A rare subtype consisting of lymphoblasts that express surface immunoglobulins and have a chromosomal translocation similar to that of Burkitt's lymphoma." [Dorlands Medical Dictionary:MerckSource]
synonym: "acute lymphoblastic leukemia cell, B-cell type" RELATED []
synonym: "B-cell leukemia cell" RELATED []
synonym: "Burkitt-like acute lymphoblastic leukemia cell" RELATED []
is_a: BTO:0000731 ! acute lymphoblastic leukemia cell

[Term]
id: BTO:0001101
name: pons
namespace: BrendaTissueOBO
def: "A broad mass of chiefly transverse nerve fibers conspicuous on the ventral surface of the brain of man and lower mammals at the anterior end of the medulla oblongata." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pons]
relationship: part_of BTO:0000146 ! brain stem
relationship: part_of BTO:0000673 ! metencephalon

[Term]
id: BTO:0001102
name: blood vessel
namespace: BrendaTissueOBO
def: "Any of the vessels through which blood circulates in the body." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=blood+vessel]
relationship: part_of BTO:0001085 ! vascular system

[Term]
id: BTO:0001103
name: skeletal muscle
namespace: BrendaTissueOBO
alt_id: BTO:0002606
def: "A usually voluntary muscle made up of elongated, multinucleated, transversely striated muscle fibers, having principally bony attachments." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "skeletal muscle cell" EXACT []
synonym: "striated muscle" RELATED []
relationship: part_of BTO:0001369 ! vertebrate muscular system
relationship: part_of BTO:0001486 ! skeletal system

[Term]
id: BTO:0001104
name: cranial nerve
namespace: BrendaTissueOBO
def: "Any of several nerves that arise in pairs from the brainstem and reach the periphery through openings in the skull. There are 12 such pairs in mammals, birds, and reptiles and usually 10 pairs in amphibians and fish." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000925 ! nerve

[Term]
id: BTO:0001105
name: insular cortex
namespace: BrendaTissueOBO
def: "The insula is a portion of the cerebral cortex that is not visible until the margins of the lateral sulcus are opened up, or, as in this case, removed. The insular cortex is roughly triangular. Originally part of the superficial cortex, in higher mammals it became submerged beneath the expanding cortex around it, thereby remaining relatively close to the basal ganglia of the hemisphere. Complete submergence of the insular cortex is a feature of the human brain and is not found even in other primates." [The Human Brain \, Chapter 4 \, The Brainstem:http\://www.vh.org/adult/provider/anatomy/BrainAnatomy/Ch4Text/Section05.html]
relationship: part_of BTO:0000233 ! cerebral cortex

[Term]
id: BTO:0001106
name: T-cell acute lymphoblastic leukemia cell
namespace: BrendaTissueOBO
def: "A type of acute lymphoblastic leukemia (ALL), a cancer of the lymphocyte-forming cells called lymphoblasts." [Wikipedia:The Free Encyclopedia]
synonym: "acute lymphoblastic leukemia cell, T-cell type" RELATED []
synonym: "acute T-lymphocytic leukemia cell" RELATED []
synonym: "T-ALL cell" RELATED []
synonym: "T-cell leukemia cell" RELATED []
is_a: BTO:0000731 ! acute lymphoblastic leukemia cell

[Term]
id: BTO:0001107
name: preadipocyte
namespace: BrendaTissueOBO
def: "A precursor to an adipocyte." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000443 ! adipocyte

[Term]
id: BTO:0001108
name: mitral cell layer
namespace: BrendaTissueOBO
relationship: part_of BTO:0000961 ! olfactory bulb

[Term]
id: BTO:0001109
name: HTC-116 cell
namespace: BrendaTissueOBO
def: "Human colon; colorectal carcinoma cell line from a male organism." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "HTC 116 cell" RELATED []
synonym: "HTC116 cell" RELATED []
is_a: BTO:0001616 ! colorectal cancer cell line

[Term]
id: BTO:0001110
name: prepupa
namespace: BrendaTissueOBO
def: "1: An inactive stage just before the pupa in the development of certain insects. \n2:The form of an insect in this stage." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0001143 ! pupa

[Term]
id: BTO:0001111
name: preputial gland
namespace: BrendaTissueOBO
def: "Any of the small glands at the base of the glans penis that secrete smegma." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "gland of Tyson" RELATED []
is_a: BTO:0000080 ! male reproductive gland
relationship: part_of BTO:0001113 ! prepuce

[Term]
id: BTO:0001112
name: preputial gland tumor cell
namespace: BrendaTissueOBO
relationship: DRV BTO:0001111 ! preputial gland

[Term]
id: BTO:0001113
name: prepuce
namespace: BrendaTissueOBO
def: "A fold of skin that covers the glans of the penis." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=prepuce]
synonym: "foreskin" RELATED []
relationship: part_of BTO:0000405 ! penis

[Term]
id: BTO:0001114
name: primary leaf
namespace: BrendaTissueOBO
def: "One of the first pair of leaves to emerge above the cotyledon during the development of a seedling; it is often morphologically distinct from subsequent leaves." [Plant breeding dictionary:http\://www.desicca.de/plant_breeding/Dictionary/Dictionary_A/dictionary_a.html]
is_a: BTO:0000713 ! leaf

[Term]
id: BTO:0001115
name: primary spermatocyte
namespace: BrendaTissueOBO
def: "A cell derived from a spermatogonium and dividing into two secondary spermatocytes; called also spermiocyte." [Dorlands Medical Dictionary:MerckSource]
synonym: "spermiocyte" RELATED []
is_a: BTO:0001275 ! spermatocyte

[Term]
id: BTO:0001116
name: floral primordium
namespace: BrendaTissueOBO
def: "Immediately next to the growing inflorescence tip is the floral primordium, which is a bump of cells representing the very youngest stage of a flower. " [Proceedings of the Royal Society B Biological Sciences:266 \, 185-190 \, 1999 \, Li \, P. and Johnston \, M.O. \, Evolution of meiosis timing during floral development]
synonym: "GRO:0005279" RELATED []
relationship: part_of BTO:0000628 ! inflorescence

[Term]
id: BTO:0001117
name: proboscis
namespace: BrendaTissueOBO
def: "1: The trunk of an elephant; also: any long flexible snout.\n2: Any of various elongated or extensible tubular processes (as the sucking organ of a butterfly) of the oral region of an invertebrate." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=proboscis]
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0001118
name: P3X63Ag8 cell
namespace: BrendaTissueOBO
def: "Mouse, BALB/c, plasmacytoma, B lymphocyte, myeloma cell line. Morphology: lymphoblast. Species: mouse, BALB/c; Tumor: myeloma; Original line: P3K Properties: IgG prod.; resistant to 8-azaguanine; fusion partner; tumorigenicity." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/, HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000456 ! plasmacytoma cell line
is_a: BTO:0000899 ! myeloma cell line
is_a: BTO:0001522 ! B-lymphocyte cell line

[Term]
id: BTO:0001119
name: procambium
namespace: BrendaTissueOBO
def: "The part of the primary meristem of a plant that forms cambium and primary vascular tissues." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=procambium]
synonym: "GRO:0000345" RELATED []
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0001120
name: epithelial cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000416 ! epithelium

[Term]
id: BTO:0001121
name: cauline leaf
namespace: BrendaTissueOBO
def: "Of, having, or growing on a stem. Used especially of leaves arising from the upper part of a stem." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000713 ! leaf
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0001122
name: procyclic form
namespace: BrendaTissueOBO
def: "African trypanosomes have a digenetic life cycle, which includes growth in the bloodstream and tissue spaces of a mammalian host and several distinct developmental stages, including the procyclic form, in an insect host (Glossina spp.,tsetse fly)." [:pp. 8818 -8821, :September 1992, :Vol. 89, High-efficiency clonal growth of bloodstream - and insect -form Trypanosoma brucei on agarose plates:Microbiology]
is_a: BTO:0000092 ! trypanosome

[Term]
id: BTO:0001123
name: peripheral ganglion
namespace: BrendaTissueOBO
is_a: BTO:0000497 ! ganglion

[Term]
id: BTO:0001124
name: promastigote
namespace: BrendaTissueOBO
def: "Any of the bodies representing the morphological (leptomonad) stage in the life cycle of certain trypanosomatid protozoa resembling the typical adult form of members of the genus Leptomonas, in which the elongate or pear-shaped cell has a central nucleus and at the anterior end a kinetoplast and a basal body from which arises a single long, slender flagellum. " [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000092 ! trypanosome

[Term]
id: BTO:0001125
name: culture condition:propanediol-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001126
name: culture condition:propionate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001127
name: primary culture
namespace: BrendaTissueOBO
def: "Freshly isolated cultures from mammalian tissues are known as primary cultures until sub-cultured. At this stage, cells are usually heterogeneous but still closely represent the parent cell types as well as in the expression of tissue specific properties. After several sub-cultures onto fresh media, the cell line will either die out or transform to become a continuous cell line. Such cell lines show many alterations from the primary cultures including change in morphology, chromosomal variation and increase in capacity to give rise to tumors in hosts with week immune systems." [University of British Columbia Biotechnology Laboratory:http\://www.biotech.ubc.ca/db/TEACH/TLEF/006.html]
is_a: BTO:0000214 ! cell culture

[Term]
id: BTO:0001128
name: prostasome
namespace: BrendaTissueOBO
def: "Prostasomes are submicron, membrane-surrounded organelles produced by the epithelial cells of the human prostate gland and are present in appreciable amounts in normal human semen." [Biochimica Clinica:23(4) \, 227-232 \, 1999 \, Ronquist \, G. \, Prostasomes are Pluripotent and Well - Organized Organelles in Human Semen]
relationship: DRV BTO:0001129 ! prostate gland
relationship: part_of BTO:0001230 ! semen

[Term]
id: BTO:0001129
name: prostate gland
namespace: BrendaTissueOBO
def: "A firm partly muscular partly glandular body that is situated about the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=prostate+gland]
synonym: "prostate" RELATED []
is_a: BTO:0000080 ! male reproductive gland
is_a: BTO:0003096 ! internal male genital organs

[Term]
id: BTO:0001130
name: prostate gland cancer cell
namespace: BrendaTissueOBO
def: "A malignant tumour cell of glandular origin in the prostate. Over 95% are adenocarcinomas." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
synonym: "prostate cancer cell" RELATED []
synonym: "prostate carcinoma cell" RELATED []
synonym: "prostate tumor cell" RELATED []
synonym: "prostate tumour cell" RELATED []
relationship: DRV BTO:0001129 ! prostate gland

[Term]
id: BTO:0001131
name: BHK cell
namespace: BrendaTissueOBO
def: "Baby hamster kidney cell line." [PMID:14705734]
is_a: BTO:0000067 ! kidney cell line

[Term]
id: BTO:0001132
name: shoot base
namespace: BrendaTissueOBO
relationship: part_of BTO:0001243 ! shoot

[Term]
id: BTO:0001133
name: pre-B-lymphocyte
namespace: BrendaTissueOBO
synonym: "pre-B-cell" RELATED []
relationship: DRV BTO:0003104 ! pro-B-lymphocyte

[Term]
id: BTO:0001134
name: protonema
namespace: BrendaTissueOBO
def: "The primary usually filamentous thalloid stage of the gametophyte in mosses and in some liverworts comparable to the prothallium in ferns." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=protonema]
is_a: BTO:0000495 ! gametophyte

[Term]
id: BTO:0001135
name: protoxylem
namespace: BrendaTissueOBO
def: "The first-formed xylem developing from procambium and consisting of narrow cells with annular, spiral, or scalariform wall thickenings." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=protoxylem]
synonym: "GRO:0000272" RELATED []
relationship: DRV BTO:0001119 ! procambium

[Term]
id: BTO:0001136
name: proventriculus
namespace: BrendaTissueOBO
def: "1: The glandular or true stomach of a bird that is situated between the crop and gizzard.\n2: A muscular dilatation of the foregut in most mandibulate insects that is armed internally with chitinous teeth or plates for triturating food.3: The thin-walled sac in front of the gizzard of an earthworm." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=proventriculus]
relationship: part_of BTO:0000058 ! alimentary canal

[Term]
id: BTO:0001137
name: right colon mucosa
namespace: BrendaTissueOBO
is_a: BTO:0000271 ! colonic mucosa
relationship: part_of BTO:0000649 ! right colon

[Term]
id: BTO:0001138
name: somatic embryo
namespace: BrendaTissueOBO
def: "An organized embryonic structure morphologically similar to a zygotic embryo but initiated from somatic (non-zygotic) cells. Under in vitro conditions, somatic embryos go through developmental processes similar to embryos of zygotic origin." [Dictionary of Genomics (Japan):http\://cny.new21.net/dictionary/s-e.html]
synonym: "somatic embryoid" RELATED []
is_a: BTO:0000379 ! embryo

[Term]
id: BTO:0001139
name: pseudoplasmodium
namespace: BrendaTissueOBO
def: "A multinucleate plasmodium-like body formed by aggregation of myxamoebae without fusion of their protoplasm." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0002007 ! aggregation stage
relationship: part_of BTO:0001494 ! fungus

[Term]
id: BTO:0001140
name: psoas
namespace: BrendaTissueOBO
def: "Either of two muscles of the loin that rotate the hip joint and flex the spine. " [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0001261 ! abdominal muscle
relationship: part_of BTO:0001505 ! loin

[Term]
id: BTO:0001141
name: pulmonary artery endothelial cell
namespace: BrendaTissueOBO
synonym: "PAEC cell" RELATED []
is_a: BTO:0001176 ! endothelial cell
relationship: part_of BTO:0000137 ! pulmonary artery endothelium

[Term]
id: BTO:0001142
name: pulp
namespace: BrendaTissueOBO
def: "The soft, succulent part of a fruit usually composed of mesocarp." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pulp]
synonym: "fruit pulp" RELATED []
relationship: part_of BTO:0000486 ! fruit

[Term]
id: BTO:0001143
name: pupa
namespace: BrendaTissueOBO
def: "An intermediate usually quiescent stage of a metamorphic insect (as a bee, moth, or beetle) that occurs between the larva and the imago, is usually enclosed in a cocoon or protective covering, and undergoes internal changes by which larval structures are replaced by those typical of the imago." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pupa]
is_a: BTO:0000854 ! zygote

[Term]
id: BTO:0001144
name: chloronema
namespace: BrendaTissueOBO
def: "The primary photosynthetic part of the moss protonema, typically green, having numerous chloroplasts and consisting of short cells with perpendicular end walls." [Glossarium Polyglottum Bryoloigiae:http\://mobot.mobot.org/cgi-bin/search_vast?GLOSE=208]
relationship: part_of BTO:0001134 ! protonema

[Term]
id: BTO:0001145
name: pre-T-lymphocyte
namespace: BrendaTissueOBO
synonym: "pre-T-cell" RELATED []
synonym: "prothymocyte" RELATED []
is_a: BTO:0000782 ! T-lymphocyte

[Term]
id: BTO:0001146
name: pyloric region
namespace: BrendaTissueOBO
def: "Pylorus: the opening from the vertebrate stomach into the intestine." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=pylorus]
relationship: part_of BTO:0000511 ! gastrointestinal tract

[Term]
id: BTO:0001147
name: culture condition:pyridoxine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001148
name: BALL-1 cell
namespace: BrendaTissueOBO
def: "Human acute lymphoblastoid leukemia cell line from peripheral blood." [Cell Name Index:http\://www.jhsf.or.jp/bank/CellName.html]
is_a: BTO:0002144 ! acute lymphoblastic leukemia cell line

[Term]
id: BTO:0001149
name: quadriceps
namespace: BrendaTissueOBO
def: "The greater extensor muscle of the front of the thigh that is divided into four parts: rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis." [Dorlands Medical Dictionary:MerckSource, From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=quadriceps]
synonym: "musculus quadriceps femoris" RELATED []
synonym: "quadriceps muscle of thigh" RELATED []
is_a: BTO:0000151 ! extensor
is_a: BTO:0001367 ! thigh muscle
relationship: part_of BTO:0001376 ! thigh

[Term]
id: BTO:0001150
name: culture condition:quinaldine-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001151
name: MOLT-4F cell
namespace: BrendaTissueOBO
def: "Human acute T lymphoblastic leukemia from peripheral blood." [Cell Name Index:http\://www.jhsf.or.jp/bank/CellName.html]
is_a: BTO:0000873 ! MOLT-4 cell

[Term]
id: BTO:0001152
name: radicle
namespace: BrendaTissueOBO
def: "The lower part of the axis of a plant embryo or seedling." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=radicle]
relationship: part_of BTO:0001228 ! seedling
relationship: part_of BTO:0001233 ! plant embryo

[Term]
id: BTO:0001153
name: radular muscle
namespace: BrendaTissueOBO
relationship: part_of BTO:0001266 ! invertebrate muscular system
relationship: part_of BTO:0001506 ! radula

[Term]
id: BTO:0001154
name: RAJI cell
namespace: BrendaTissueOBO
def: "Human Burkitt's lymphoma cell line, established from the left maxilla of a 12-year-old African boy with Burkitt's lymphoma in 1963; first continuous human hematopoietic cell line; classified as risk category 1 according to the German Central Commission for Biological Safety (ZKBS)." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000889 ! Burkitt lymphoma cell line

[Term]
id: BTO:0001155
name: ray cell
namespace: BrendaTissueOBO
def: "A primary tissue composed of medullary ray: radiating bands of parenchyma cells extending between the vascular bundles of herbaceous dicotyledonous stems and connecting the pith with the cortex." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=ray+cell]
is_a: BTO:0000999 ! parenchyma

[Term]
id: BTO:0001156
name: node
namespace: BrendaTissueOBO
def: "The point on a stem at which leaves and buds are attached." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "stem node" RELATED []
relationship: part_of BTO:0001300 ! stem

[Term]
id: BTO:0001157
name: rectal gland
namespace: BrendaTissueOBO
def: "An evagination of the terminal portion of the intestine of Elasmobranchii. Function formerly thought to be related to digestion or excretion, but now considered to secrete high concentrations of excess sodium chloride. Found also in the coelacanth Latimeria chalumnae." [Dictionary of Ichthyology:http\://www.briancoad.com/Dictionary/Introduction.htm]
relationship: part_of BTO:0001158 ! rectum

[Term]
id: BTO:0001158
name: rectum
namespace: BrendaTissueOBO
def: "The terminal part of the intestine from the sigmoid flexure to the anus." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=rectum]
synonym: "intestinum rectum" RELATED []
relationship: part_of BTO:0000706 ! large intestine
relationship: part_of BTO:0001613 ! colorectum

[Term]
id: BTO:0001159
name: aorta thoracica smooth muscle
namespace: BrendaTissueOBO
synonym: "thoracic aorta smooth muscle" RELATED []
is_a: BTO:0001685 ! aortic smooth muscle
relationship: part_of BTO:0000157 ! aorta thoracica

[Term]
id: BTO:0001160
name: red bone marrow
namespace: BrendaTissueOBO
def: "Marrow of developing bone, of the ribs, vertebrae, and many of the smaller bones; it is the site of production of erythrocytes and granular leukocytes." [Dorlands Medical Dictionary:MerckSource]
synonym: "medulla ossium rubra" RELATED []
synonym: "red marrow" RELATED []
is_a: BTO:0000141 ! bone marrow

[Term]
id: BTO:0001161
name: chorionic villus
namespace: BrendaTissueOBO
def: "One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000252 ! chorion

[Term]
id: BTO:0001162
name: apocrine gland
namespace: BrendaTissueOBO
def: "A gland whose discharged secretion contains part of the secreting cells." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000522 ! gland

[Term]
id: BTO:0001163
name: REH cell
namespace: BrendaTissueOBO
def: "Human B cell precursor leukemia established from the peripheral blood of a 15-year-old North African girl with acute lymphoblastic leukemia (ALL at first relapse) in 1973." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0002144 ! acute lymphoblastic leukemia cell line

[Term]
id: BTO:0001164
name: megakaryoblast
namespace: BrendaTissueOBO
def: "The earliest cytologically identifiable precursor in the thrombocytic series, a large cell that matures to form a promegakaryocyte." [Dorlands Medical Dictionary:MerckSource]
synonym: "megacaryoblast" RELATED []
relationship: part_of BTO:0000141 ! bone marrow

[Term]
id: BTO:0001165
name: renal artery
namespace: BrendaTissueOBO
def: "A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0000573 ! artery
is_a: BTO:0000671 ! kidney

[Term]
id: BTO:0001166
name: renal cortex
namespace: BrendaTissueOBO
def: "Cortex of kidney." [Dorlands Medical Dictionary:MerckSource]
synonym: "kidney cortex" RELATED []
relationship: part_of BTO:0000671 ! kidney

[Term]
id: BTO:0001167
name: renal medulla
namespace: BrendaTissueOBO
def: "The inner section of the kidney." [Aristoteles University of Thessaloniki \, Dictionary of Medical Terms:http\://www.med.auth.gr/db/dictionary1/gr/]
synonym: "kidney medulla" RELATED []
relationship: part_of BTO:0000671 ! kidney

[Term]
id: BTO:0001168
name: rennet
namespace: BrendaTissueOBO
def: "1: The inner lining of the fourth stomach of calves and other young ruminants.\n2: A dried extract made from the stomach lining of a ruminant, used in cheesemaking to curdle milk." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000024 ! abomasum

[Term]
id: BTO:0001169
name: 3T3-F442A cell
namespace: BrendaTissueOBO
def: "Preadipocyte cell line." [PMID:12213191]
is_a: BTO:0000746 ! preadipocyte cell line

[Term]
id: BTO:0001170
name: resting cell
namespace: BrendaTissueOBO
def: "A cell that is not actively in the process of dividing." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0002322 ! cell property

[Term]
id: BTO:0001171
name: spore
namespace: BrendaTissueOBO
def: "A primitive usually unicellular often environmentally resistant dormant or reproductive body produced by plants and some microorganisms and capable of development into a new individual either directly or after fusion with another spore." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spore]
is_a: BTO:0000284 ! organism form
is_a: BTO:0000720 ! plant form
relationship: part_of BTO:0000487 ! fruitbody
relationship: part_of BTO:0000735 ! sporophyte

[Term]
id: BTO:0001172
name: reticulate body
namespace: BrendaTissueOBO
def: "The noninfectious intracellular form of Chlamydia, consisting of fibrillar nuclear material and more ribosomes that occur in elementary bodies, surrounded by a thin trilaminar wall. Reticulate bodies reproduce within vacuoles in the host cell; following the reproductive cycle, reticulate bodies condense into elementary bodies, which are released from the cell." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000284 ! organism form

[Term]
id: BTO:0001173
name: reticulocyte
namespace: BrendaTissueOBO
def: "An immature red blood cell that appears especially during regeneration of lost blood and has a fine basophilic reticulum formed of ribosomal remains." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=reticulocyte]
is_a: BTO:0000424 ! erythrocyte
is_a: BTO:0001441 ! marrow cell

[Term]
id: BTO:0001174
name: reticuloendothelial system
namespace: BrendaTissueOBO
def: "A diffuse system of cells of varying lineage that include esp. the macrophages and the phagocytic endothelial cells lining blood sinuses and that were originally grouped together because of their supposed phagocytic properties based on their ability to take up the vital dye trypan blue." [Dorlands Medical Dictionary:MerckSource]
synonym: "lymphoreticular system" RELATED []
relationship: part_of BTO:0000570 ! hematopoietic system

[Term]
id: BTO:0001175
name: retina
namespace: BrendaTissueOBO
def: "The sensory membrane that lines the eye, is composed of several layers including one containing the rods and cones, and functions as the immediate instrument of vision by receiving the image formed by the lens and converting it into chemical and nervous signals which reach the brain by way of the optic nerve." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=retina]
relationship: part_of BTO:0000439 ! eye

[Term]
id: BTO:0001176
name: endothelial cell
namespace: BrendaTissueOBO
def: "The main type of cell found in the inside lining of blood vessels, lymph vessels, and the heart.  " [Biology Dictionary \, Hyperdictionary:http\://www.hyperdictionary.com/dictionary/endothelial+cell]
relationship: part_of BTO:0000393 ! endothelium
relationship: part_of BTO:0000562 ! heart
relationship: part_of BTO:0000752 ! lymph vessel
relationship: part_of BTO:0000766 ! blood vessel endothelium

[Term]
id: BTO:0001177
name: retinal pigment epithelium
namespace: BrendaTissueOBO
def: "The pigment cell layer that nourishes the retinal cells; located just outside the retina and attached to the choroid." [Alberta Heritage Foundation of Medical Research:http\://www.ahfmr.ab.ca/hta/hta-publications/reports/intraocular99/intraocular.shtml]
synonym: "epithelium, retinal pigment" RELATED []
synonym: "retinal pigment epithelial cell" RELATED []
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0001175 ! retina

[Term]
id: BTO:0001178
name: retinoblastoma cell
namespace: BrendaTissueOBO
def: "A malignant congenital blastoma, occurring in both hereditary and sporadic forms, composed of tumor cells arising from the retinoblasts, appearing in one or both eyes in children under 5 years of age, and usually diagnosed initially by a bright white or yellow pupillary reflex (leukokoria)." [Dorlands Medical Dictionary:MerckSource]
synonym: "glioma retinae cell" RELATED []
is_a: BTO:0000526 ! glioma cell
is_a: BTO:0000579 ! eye cancer cell

[Term]
id: BTO:0001179
name: rhizophore
namespace: BrendaTissueOBO
def: "A leafless stem that produces roots. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0001300 ! stem

[Term]
id: BTO:0001180
name: idioblast
namespace: BrendaTissueOBO
def: "A plant cell committed to develop into a cell type that differs from the surrounding tissue." [Plant breeding dictionary:http\://www.desicca.de/plant_breeding/Dictionary/Dictionary_A/dictionary_a.html]
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0001181
name: rhizome
namespace: BrendaTissueOBO
def: "A somewhat elongate usually horizontal subterranean plant stem that is often thickened by deposits of reserve food material, produces shoots above and roots below, and is distinguished from a true root in possessing buds, nodes, and usually scalelike leaves." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=rhizome]
synonym: "GRO:0005811" RELATED []
relationship: DRV BTO:0001300 ! stem

[Term]
id: BTO:0001182
name: primary root
namespace: BrendaTissueOBO
def: "The main root of a plant is called the primary root; others are called secondary roots." [The New Dictionary of Cultural Literacy:Third Edition. 2002.]
synonym: "GRO:0000303" RELATED []
synonym: "tap root" RELATED []
synonym: "taproot" RELATED []
is_a: BTO:0001188 ! root

[Term]
id: BTO:0001183
name: secondary root
namespace: BrendaTissueOBO
def: "The main root of a plant is called the primary root; others are called secondary roots." [The New Dictionary of Cultural Literacy:Third Edition. 2002.]
relationship: part_of BTO:0001182 ! primary root

[Term]
id: BTO:0001184
name: rind
namespace: BrendaTissueOBO
def: "A tough outer covering such as bark or the skin of some fruits." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=rind]
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0001185
name: RINm5F cell
namespace: BrendaTissueOBO
def: "Insulin secreting pancreatic beta cell line." [PMID:9545239]
is_a: BTO:0000183 ! pancreatic cell line

[Term]
id: BTO:0001186
name: receptacle
namespace: BrendaTissueOBO
def: "The end of the flower stalk upon which the floral organs are borne." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=receptacle]
relationship: part_of BTO:0002244 ! flower stalk

[Term]
id: BTO:0001187
name: roe
namespace: BrendaTissueOBO
def: "The eggs of a fish especially when still enclosed in the ovarian membrane." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=roe]
is_a: BTO:0000369 ! egg

[Term]
id: BTO:0001188
name: root
namespace: BrendaTissueOBO
def: "The usually underground part of a seed plant body that originates usually from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support, and differs from a stem especially in lacking nodes, buds, and leaves." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=root]
synonym: "GRO:0005338" RELATED []
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0001189
name: FAZA cell
namespace: BrendaTissueOBO
def: "Rat hepatoma cell line." [PMID:1917955]
is_a: BTO:0000578 ! hepatoma cell line

[Term]
id: BTO:0001190
name: root nodule
namespace: BrendaTissueOBO
def: "Gall-like structures on the roots of legumes that contain symbiotic nitrogen-fixing bacteria. " [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "nodule" RELATED []
relationship: part_of BTO:0001188 ! root

[Term]
id: BTO:0001191
name: root tip
namespace: BrendaTissueOBO
def: "The root tip is the tip of the root and contains the root cap and the apical meristem (the actively growing region)." [Botany and Paleobotany Dictionary:Plant Glossary]
synonym: "GRO:0000251" RELATED []
relationship: part_of BTO:0001188 ! root

[Term]
id: BTO:0001192
name: rootlet
namespace: BrendaTissueOBO
def: "A small root." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=rootlet]
is_a: BTO:0001188 ! root
relationship: part_of BTO:0001084 ! plantlet

[Term]
id: BTO:0001193
name: C-127 cell
namespace: BrendaTissueOBO
def: "Murine mammary tumor line from a female mus musculus." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
synonym: "C127cell" RELATED []
is_a: BTO:0000356 ! breast cancer cell line

[Term]
id: BTO:0001194
name: rumen
namespace: BrendaTissueOBO
def: "The large first compartment of the stomach of a ruminant in which cellulose is broken down by the action of symbiotic microorganisms." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=rumen]
synonym: "paunch" RELATED []
is_a: BTO:0000480 ! forestomach

[Term]
id: BTO:0001195
name: rumen epithelium
namespace: BrendaTissueOBO
def: "The rumen epithelium is the tissue which lines the largest of the four fore stomachs in the ruminant animal (cows and sheep). Rumen epithelial cells are important because they are responsible for the absorption of nutrients from the rumen into the blood." [PMID:10764086]
is_a: BTO:0000416 ! epithelium
relationship: part_of BTO:0001194 ! rumen

[Term]
id: BTO:0001196
name: SF-21 cell
namespace: BrendaTissueOBO
def: "Insect - fall armyworm (Spodoptera frugiperda) cell line. This cell line (full name: IPLB-SF-21-AE) was derived from immature ovaries of fall armyworm Spodoptera frugiperda pupae (species Spodoptera frugiperda, family Sciaridae, order Lepidoptera); cells are susceptible to Baculovirus infection." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "Sf21 cell" RELATED []
is_a: BTO:0000977 ! ovary cell line

[Term]
id: BTO:0001197
name: S-180 cell
namespace: BrendaTissueOBO
def: "Mouse sarcoma cell line, from an adult mus musculus;\nHighly malignant mouse sarcoma cells, often passaged in ascites form." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/, The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "CCRF S-180 II cell" RELATED []
synonym: "S180 cell" RELATED []
synonym: "sarcoma 180 cell" RELATED []
is_a: BTO:0000400 ! sarcoma cell line

[Term]
id: BTO:0001198
name: atrial gland
namespace: BrendaTissueOBO
def: "The atrial gland is an exocrine organ that secretes into the oviduct of Aplysia californica and expresses three homologous genes belonging to the egg-laying hormone gene family." [ISSN:0302-766X (printed version) ISSN 1432-0878 (electronic version)]
is_a: BTO:0000254 ! female reproductive gland
is_a: BTO:0000765 ! exocrine gland

[Term]
id: BTO:0001199
name: EBTr (NBL-4) cell
namespace: BrendaTissueOBO
def: "Embryonic bovine, trachea cell line; established from a male cow (Bos taurus) embryo." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000669 ! embryonic cell line

[Term]
id: BTO:0001200
name: aorta thoracica smooth muscle cell line
namespace: BrendaTissueOBO
is_a: BTO:0001964 ! aorta smooth muscle cell line
is_a: BTO:0002195 ! vascular smooth muscle cell line
relationship: DRV BTO:0001159 ! aorta thoracica smooth muscle

[Term]
id: BTO:0001201
name: rosette
namespace: BrendaTissueOBO
def: "A cluster of leaves in crowded circles or spirals arising basally from a crown (as in the dandelion) or apically from an axis with greatly shortened internodes (as in many tropical palms)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=rosette]
relationship: REL BTO:0000713 ! leaf

[Term]
id: BTO:0001202
name: saliva
namespace: BrendaTissueOBO
def: "A slightly alkaline secretion of water, mucin, protein, salts, and often a starch-splitting enzyme (as ptyalin) that is secreted into the mouth by salivary glands, lubricates ingested food, and often begins the breakdown of starches." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=saliva]
relationship: DRV BTO:0001203 ! salivary gland

[Term]
id: BTO:0001203
name: salivary gland
namespace: BrendaTissueOBO
def: "The glands of the oral cavity whose combined secretion constitutes the saliva." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000765 ! exocrine gland
relationship: part_of BTO:0001090 ! mouth

[Term]
id: BTO:0001204
name: salt gland
namespace: BrendaTissueOBO
def: "A specialized gland in marine animals that excretes the excess salt taken into the body." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000431 ! excretory gland

[Term]
id: BTO:0001205
name: RT4-D6P2T cell
namespace: BrendaTissueOBO
def: "Rat,  nervous system, immature, Schwann cell derived cell line." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "D6P2T cell" RELATED []
is_a: BTO:0000872 ! oligodendrocytic cell line
is_a: BTO:0001216 ! Schwann cell line

[Term]
id: BTO:0001206
name: sarcocarp
namespace: BrendaTissueOBO
def: "The fleshy part of a stone fruit, situated between the skin, or epicarp, and the stone, or endocarp, as in a peach. The term has also been used to denote, any fruit which is fleshy throughout. " [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
relationship: part_of BTO:0001017 ! pericarp

[Term]
id: BTO:0001207
name: sarcoma cell
namespace: BrendaTissueOBO
def: "A malignant neoplasm cell arising in tissue of mesodermal origin (as connective tissue, bone, cartilage, or striated muscle)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sarcoma]
is_a: BTO:0000372 ! bone cancer cell
is_a: BTO:0001801 ! skeletal muscle cancer cell
relationship: DRV BTO:0000206 ! cartilage

[Term]
id: BTO:0001208
name: larynx
namespace: BrendaTissueOBO
def: "The modified upper part of the trachea of air-breathing vertebrates that in humans, most other mammals, and a few lower forms contains the vocal cords." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=larynx]
relationship: part_of BTO:0000828 ! throat

[Term]
id: BTO:0001209
name: umbilical cord cell line
namespace: BrendaTissueOBO
is_a: BTO:0001975 ! placental cell line
relationship: DRV BTO:0001415 ! umbilical cord

[Term]
id: BTO:0001210
name: SGS cell
namespace: BrendaTissueOBO
def: "Rat Galliera sarcoma cell line from a 2 months old rat Galliera; Tumor: sarcoma Viruses: contains SG-RaLV (Retrovirus type C)." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0000400 ! sarcoma cell line

[Term]
id: BTO:0001211
name: ECV304 cell
namespace: BrendaTissueOBO
def: "Human umbilical cord cell line; endothelial-like from a new born asiatic female; spontaneously transformed." [HyperCLDB:http\://www.biotech.ist.unige.it/]
is_a: BTO:0001209 ! umbilical cord cell line

[Term]
id: BTO:0001212
name: Rous sarcoma cell
namespace: BrendaTissueOBO
def: "Acell type of avian sarcoma transmitted by a retrovirus; it metastasizes freely and is sometimes highly lethal. Experimental inoculation into other fowls produces similar growths. This was the first sarcoma known to be caused by a virus." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0001207 ! sarcoma cell

[Term]
id: BTO:0001213
name: Yoshida ascites sarcoma cell
namespace: BrendaTissueOBO
is_a: BTO:0001214 ! Yoshida sarcoma cell

[Term]
id: BTO:0001214
name: Yoshida sarcoma cell
namespace: BrendaTissueOBO
is_a: BTO:0001207 ! sarcoma cell

[Term]
id: BTO:0001215
name: sartorius
namespace: BrendaTissueOBO
def: "A muscle that crosses the front of the thigh obliquely, assists in rotating the leg to the cross-legged position in which the knees are spread wide apart, and in humans is the longest muscle." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sartorius]
is_a: BTO:0001367 ! thigh muscle
relationship: part_of BTO:0001376 ! thigh

[Term]
id: BTO:0001216
name: Schwann cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001220 ! Schwann cell

[Term]
id: BTO:0001217
name: scape
namespace: BrendaTissueOBO
def: "A peduncle arising at or beneath the surface of the ground in an acaulescent plant (as the tulip); broadly: a flower stalk." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=scape]
synonym: "GRO:0005817" RELATED []
is_a: BTO:0001300 ! stem

[Term]
id: BTO:0001218
name: scapula
namespace: BrendaTissueOBO
def: "Either of a pair of large triangular bones lying one in each dorsal lateral scapula: part of the thorax, being the principal bone of the corresponding half of the shoulder girdle, and articulating with the corresponding clavicle or coracoid." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=scapula+cartilage]
synonym: "scapula bone" RELATED []
synonym: "shoulder blade" RELATED []
is_a: BTO:0000140 ! bone

[Term]
id: BTO:0001219
name: MEB-4 cell
namespace: BrendaTissueOBO
def: "Mouse melanoma cell line." [PMID:12517748]
synonym: "MEB4 cell" RELATED []
is_a: BTO:0000849 ! melanoma cell line

[Term]
id: BTO:0001220
name: Schwann cell
namespace: BrendaTissueOBO
def: "The myelin-secreting cell surrounding a myelinated nerve fiber between two nodes of Ranvier." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=Schwann+cell]
relationship: part_of BTO:0001028 ! peripheral nervous system

[Term]
id: BTO:0001221
name: sciatic nerve
namespace: BrendaTissueOBO
def: "The largest nerve of the body: origin, sacral plexus-L4-S3; it leaves the pelvis through the greater sciatic foramen; branches, divides into the tibial and common peroneal nerves, usually in lower third of thigh; distribution-see individual branches, in this table; modality, general sensory and motor." [Dorlands Medical Dictionary:MerckSource]
synonym: "nervus ischiadicus" RELATED []
synonym: "nervus sciaticus" RELATED []
is_a: BTO:0000925 ! nerve

[Term]
id: BTO:0001222
name: sclerenchyma
namespace: BrendaTissueOBO
def: "A protective or supporting tissue in higher plants composed of cells with walls thickened and often lignified." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sclerenchyma]
synonym: "GRO:0005427" RELATED []
relationship: part_of BTO:0001243 ! shoot

[Term]
id: BTO:0001223
name: scutellum
namespace: BrendaTissueOBO
def: "The single cotyledon in monocotyledon seeds such as grass seeds. " [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005344" RELATED []
is_a: BTO:0000300 ! cotyledon

[Term]
id: BTO:0001224
name: second instar larva
namespace: BrendaTissueOBO
def: "Instar: a stage in the life of an arthropod (as an insect) between two successive molts." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=instar]
is_a: BTO:0000707 ! larva

[Term]
id: BTO:0001225
name: MKN-45 cell
namespace: BrendaTissueOBO
def: "Human gastric adenocarcinoma, established from the poorly differentiated adenocarcinoma of the stomach (medullary type) of a 62-year-old woman." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "MKN45 cell" RELATED []
is_a: BTO:0002380 ! gastric adenocarcinoma cell line

[Term]
id: BTO:0001226
name: seed
namespace: BrendaTissueOBO
def: "A matured ovule containing an embryo and food supply and covered by a seed coat." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005339" RELATED []
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0001227
name: seed coat
namespace: BrendaTissueOBO
def: "The outer layer of a seed that is developed from the integuments of the ovule; the testa." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005359" RELATED []
synonym: "tegmen" RELATED []
synonym: "testa" RELATED []
relationship: part_of BTO:0001226 ! seed

[Term]
id: BTO:0001228
name: seedling
namespace: BrendaTissueOBO
def: "The embryonic product of the germination of a seed; the young shoot and root axis." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
is_a: BTO:0000720 ! plant form
is_a: BTO:0001461 ! whole plant

[Term]
id: BTO:0001229
name: IMR-90 cell
namespace: BrendaTissueOBO
def: "Normal lung fibroblast cell line from a human female. The human diploid fibroblast strain IMR-90 was derived by W.W. Nichols and associates from the lungs of a 16-week female fetus." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000161 ! lung fibroblast cell line
is_a: BTO:0001242 ! fetal cell line

[Term]
id: BTO:0001230
name: semen
namespace: BrendaTissueOBO
def: "A viscid whitish fluid of the male reproductive tract consisting of spermatozoa suspended in secretions of accessory glands." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=semen]
synonym: "seminal fluid" RELATED []
synonym: "sperm" RELATED []
relationship: part_of BTO:0000082 ! male reproductive system

[Term]
id: BTO:0001231
name: trigeminal ganglion
namespace: BrendaTissueOBO
def: "A ganglion on the sensory root of the fifth cranial nerve, situated in a cleft within the dura mater (trigeminal cave) on the anterior surface of the petrous portion of the temporal bone, and giving off the ophthalmic and maxillary and part of the mandibular nerve; it contains the cells of origin of most of the sensory fibers of the trigeminal nerve. " [Dorlands Medical Dictionary:MerckSource]
synonym: "ganglion of trigeminal nerve" RELATED []
synonym: "ganglion trigeminale" RELATED []
synonym: "Gasser's ganglion" RELATED []
synonym: "gasserian ganglion" RELATED []
synonym: "semilunar ganglion" RELATED []
is_a: BTO:0000106 ! cranial ganglion

[Term]
id: BTO:0001232
name: seminal plasma
namespace: BrendaTissueOBO
def: "The fluid portion of the semen, in which the spermatozoa are suspended." [Dorlands Medical Dictionary:MerckSource]
synonym: "prostate fluid" RELATED []
synonym: "prostatic fluid" RELATED []
synonym: "seminal fluid" RELATED []
relationship: DRV BTO:0001129 ! prostate gland
relationship: part_of BTO:0001230 ! semen

[Term]
id: BTO:0001233
name: plant embryo
namespace: BrendaTissueOBO
def: "The early developmental stage that, through embryological development, ultimately becomes an adult individual. In plants, that portion of a seed that will form the growing seedling following germination; it has a radicle, apical meristem, and embryonic leaf or leaves. " [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
synonym: "GRO:0005343" RELATED []
synonym: "plant germ" RELATED []
is_a: BTO:0001461 ! whole plant
relationship: part_of BTO:0001226 ! seed

[Term]
id: BTO:0001234
name: seminal vesicle
namespace: BrendaTissueOBO
def: "Either of a pair of glandular pouches that lie one on either side of the male reproductive tract and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=seminal+vesicle]
synonym: "glandula seminalis" RELATED []
synonym: "glandula vesiculosa" RELATED []
synonym: "seminal gland" RELATED []
synonym: "vesicula seminalis" RELATED []
is_a: BTO:0003096 ! internal male genital organs
relationship: part_of BTO:0000082 ! male reproductive system

[Term]
id: BTO:0001235
name: seminiferous tubule
namespace: BrendaTissueOBO
def: "One of two or three twisted, curved tubules in each lobule of the testis in which spermatozoa develop." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0001363 ! testis

[Term]
id: BTO:0001236
name: semitendinosus
namespace: BrendaTissueOBO
def: "A fusiform muscle of the posterior and inner part of the thigh that arises from the ischial tuberosity along with the biceps femoris, that is inserted by a long round tendon which forms part of the inner hamstring into the inner surface of the upper part of the shaft of the tibia, and that acts to flex the leg and rotate it medially and to extend the thigh." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "musculus semitendinosus" RELATED []
synonym: "semitendinosus muscle" RELATED []
is_a: BTO:0003179 ! hamstring muscle

[Term]
id: BTO:0001237
name: sensillum
namespace: BrendaTissueOBO
def: "A simple epithelial sense organ of an invertebrate (as an insect) usually in the form of a spine, plate, rod, cone, or peg that is composed of one or a few cells with a nerve connection." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sensillum]
is_a: BTO:0000202 ! sense organ
relationship: part_of BTO:0000420 ! neck

[Term]
id: BTO:0001238
name: Sertoli cell
namespace: BrendaTissueOBO
def: "Any of the elongated, striated cells of the seminiferous tubules of the testis, to which spermatids attach for nourishment during spermatogenesis." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0002315 ! supporting cell
relationship: part_of BTO:0001235 ! seminiferous tubule

[Term]
id: BTO:0001239
name: serum
namespace: BrendaTissueOBO
def: "1: The watery portion of an animal fluid remaining after coagulation: a (1): blood serum (2): antiserum b: whey c: a normal or pathological serous fluid (as in a blister).\n2: The watery part of a plant fluid." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=serum]
relationship: part_of BTO:0000570 ! hematopoietic system

[Term]
id: BTO:0001240
name: SF-9 cell
namespace: BrendaTissueOBO
def: "Insect - fall armyworm (Spodoptera frugiperda) cell line, cloned from the parent cell line, IPLB-SF-21-AE, derived from pupal ovarian tissue of the fall armyworm (species Spodoptera frugiperda, family Sciaridae, order Lepidoptera); cells are susceptible to infection with MNPV and other Baculoviruses; cells can be used with Baculovirus expression vectors. It was derived from SF-21." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "Sf9 cell" RELATED []
relationship: DRV BTO:0001196 ! SF-21 cell

[Term]
id: BTO:0001241
name: shell gland
namespace: BrendaTissueOBO
def: "1: A glandular organ in which the rudimentary shell is formed in embryonic mollusks.\n2: A glandular organ which secretes the eggshells of various worms, crustacea, mollusks, etc." [Webster's Revised Unabridged Dictionary:1913]
is_a: BTO:0000254 ! female reproductive gland
relationship: part_of BTO:0000379 ! embryo

[Term]
id: BTO:0001242
name: fetal cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0000449 ! fetus

[Term]
id: BTO:0001243
name: shoot
namespace: BrendaTissueOBO
def: "A sending out of new growth or the growth sent out: as a stem or branch with its leaves and appendages especially when not yet mature." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=shoot]
synonym: "GRO:0005300" RELATED []
is_a: BTO:0001461 ! whole plant

[Term]
id: BTO:0001244
name: urinary tract
namespace: BrendaTissueOBO
def: "The organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra." [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
is_a: BTO:0001491 ! viscus

[Term]
id: BTO:0001245
name: urothelium
namespace: BrendaTissueOBO
def: "The lining of the ureters, bladder, and urethra. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
relationship: part_of BTO:0001409 ! ureter
relationship: part_of BTO:0001418 ! urinary bladder
relationship: part_of BTO:0001426 ! urethra

[Term]
id: BTO:0001246
name: flexor digitorum profundus
namespace: BrendaTissueOBO
def: "A deep muscle of the ulnar side of the forearm that flexes esp. the terminal phalanges of the four fingers . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000479 ! forelimb muscle
is_a: BTO:0001257 ! flexor

[Term]
id: BTO:0001247
name: sieve tube
namespace: BrendaTissueOBO
def: "Found in phloem tissue, sieve tubes lack a nucleus, and are thought to be responsible for the translocation of material across the phloem tissue." [Biology-Online Dictionary:http\://www.biology-online.org/dictionary/]
synonym: "GRO:0005638" RELATED []
relationship: part_of BTO:0001058 ! phloem

[Term]
id: BTO:0001248
name: T-47D cell
namespace: BrendaTissueOBO
def: "Human ductal breast carcinoma ductal cell line. Morphology: epithelial-likeSpecies: human female 54 years old; Tissue: breast; Tumor: carcinoma, ductal; Derived from: T47, originally derived from pleural effusion." [HyperCLDB:http\://www.biotech.ist.unige.it/]
synonym: "T47-D cell" RELATED []
synonym: "T47D cell" RELATED []
relationship: DRV BTO:0003741 ! T-47 cell

[Term]
id: BTO:0001249
name: silique
namespace: BrendaTissueOBO
def: "A narrow elongated two-valved usually many-seeded capsule that is characteristic of the mustard family, opens by sutures at either margin, and has two parietal placentas." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=silique]
synonym: "GRO:0005592" RELATED []
is_a: BTO:0000173 ! fruit capsule

[Term]
id: BTO:0001250
name: silk gland
namespace: BrendaTissueOBO
def: "Any of the glands in silk-spinning insects and spiders that secrete a protein liquid that hardens into silk on exposure to air." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000765 ! exocrine gland

[Term]
id: BTO:0001251
name: liver sinusoidal endothelial cell
namespace: BrendaTissueOBO
def: "Liver sinusoidal endothelial cells (LSEC) constitute the sinusoidal wall, also called the endothelium, or endothelial lining." [PMID:12437787]
synonym: "LSEC" RELATED []
is_a: BTO:0001176 ! endothelial cell
relationship: part_of BTO:0000759 ! liver
relationship: part_of BTO:0000831 ! liver reticuloendothelial system

[Term]
id: BTO:0001252
name: tibia
namespace: BrendaTissueOBO
def: "The shin bone: the inner and larger bone of the leg below the knee; it articulates with the femur and head of the fibula above and with the talus below. " [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000140 ! bone
relationship: part_of BTO:0002345 ! hindlimb

[Term]
id: BTO:0001253
name: skin
namespace: BrendaTissueOBO
def: "The integument of an animal (as a fur-bearing mammal or a bird) separated from the body usually with its hair or feathers." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=skin]
is_a: BTO:0000634 ! integument

[Term]
id: BTO:0001254
name: sweat
namespace: BrendaTissueOBO
def: "The fluid excreted from the sweat glands of the skin." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sweat]
synonym: "skin exudate" RELATED []
relationship: DRV BTO:0001331 ! sweat gland

[Term]
id: BTO:0001255
name: skin fibroblast
namespace: BrendaTissueOBO
is_a: BTO:0000452 ! fibroblast
relationship: part_of BTO:0001253 ! skin

[Term]
id: BTO:0001256
name: parasympathetic ganglion
namespace: BrendaTissueOBO
def: "One of the aggregations of cell bodies of primarily cholinergic neurons of the parasympathetic nervous system, located near to or within the wall of the organs being innervated." [Dorlands Medical Dictionary:MerckSource]
synonym: "ganglion parasympathicum" RELATED []
is_a: BTO:0000497 ! ganglion
relationship: part_of BTO:0001833 ! parasympathetic nervous system

[Term]
id: BTO:0001257
name: flexor
namespace: BrendaTissueOBO
def: "A muscle that when contracted acts to bend a joint or limb in the body." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0001103 ! skeletal muscle

[Term]
id: BTO:0001258
name: small intestine epithelium
namespace: BrendaTissueOBO
is_a: BTO:0000416 ! epithelium
is_a: BTO:0000651 ! small intestine
is_a: BTO:0000781 ! intestinal epithelium

[Term]
id: BTO:0001259
name: small intestine mucosa
namespace: BrendaTissueOBO
is_a: BTO:0000642 ! intestinal mucosa
is_a: BTO:0000651 ! small intestine

[Term]
id: BTO:0001260
name: smooth muscle
namespace: BrendaTissueOBO
def: "Muscle tissue that lacks cross striations, that is made up of elongated spindle-shaped cells having a central nucleus, and that is found in vertebrate visceral structures (as the stomach and bladder) as thin sheets performing functions not subject to conscious control by the mind and in all or most of the musculature of invertebrates other than arthropods." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=smooth+muscle]
synonym: "SMC cell" RELATED []
synonym: "smooth muscle cell" RELATED []
relationship: part_of BTO:0001369 ! vertebrate muscular system

[Term]
id: BTO:0001261
name: abdominal muscle
namespace: BrendaTissueOBO
def: "Muscles forming the wall of the abdomen including rectus abdominis, external and internal oblique muscles, transversus abdominis, and quadratus abdominis." [Medical Dictionary Online:http\://www.online-medical-dictionary.org/]
is_a: BTO:0001103 ! skeletal muscle

[Term]
id: BTO:0001262
name: soft body part
namespace: BrendaTissueOBO
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0001263
name: Friend erythroleukemia cell line
namespace: BrendaTissueOBO
is_a: BTO:0000846 ! erythroleukemia cell line
relationship: DRV BTO:0000426 ! erythroleukemia cell

[Term]
id: BTO:0001264
name: spinal ganglion
namespace: BrendaTissueOBO
def: "A ganglion on the dorsal root of each spinal nerve that is one of a series of ganglia lodging cell bodies of sensory neurons." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spinal+ganglion]
synonym: "dorsal root ganglion" RELATED []
synonym: "ganglion sensorium nervi spinalis" RELATED []
synonym: "ganglion spinale" RELATED []
is_a: BTO:0001123 ! peripheral ganglion
relationship: part_of BTO:0001279 ! spinal cord

[Term]
id: BTO:0001265
name: soleus
namespace: BrendaTissueOBO
def: "A broad flat muscle of the calf of the leg lying immediately below the gastrocnemius." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=soleus]
is_a: BTO:0000722 ! leg muscle
relationship: part_of BTO:0000721 ! leg

[Term]
id: BTO:0001266
name: invertebrate muscular system
namespace: BrendaTissueOBO
is_a: BTO:0001485 ! muscular system

[Term]
id: BTO:0001267
name: urothelial cell line
namespace: BrendaTissueOBO
relationship: DRV BTO:0001245 ! urothelium

[Term]
id: BTO:0001268
name: somatic cell
namespace: BrendaTissueOBO
def: "One of the cells of the body that compose the tissues, organs, and parts of that individual other than the germ cells." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=somatic+cell]
is_a: BTO:0002322 ! cell property

[Term]
id: BTO:0001269
name: spadix
namespace: BrendaTissueOBO
def: "A floral spike with a fleshy or succulent axis usually enclosed in a spathe. " [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spadix]
synonym: "GRO:0005418" RELATED []
is_a: BTO:0001278 ! spike

[Term]
id: BTO:0001270
name: spear
namespace: BrendaTissueOBO
def: "A usually young blade, shoot, or sprout (as of grass)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spear]
is_a: BTO:0001296 ! sprout

[Term]
id: BTO:0001271
name: leukemia cell
namespace: BrendaTissueOBO
def: "A cancer cell of the white blood cells. Leukaemias are grouped by how quickly the disease develops (acute or chronic) as well as by the type of blood cell that is affected." [Online Medical Dictionary:http\://cancerweb.ncl.ac.uk/]
is_a: BTO:0000580 ! blood cancer cell
relationship: DRV BTO:0000751 ! leukocyte

[Term]
id: BTO:0001272
name: sperm flagellum
namespace: BrendaTissueOBO
def: "The posterior, filiform part of spermatozoa, which provides sperm motility." [Medical Dictionary Online:http\://www.online-medical-dictionary.org/]
synonym: "sperm tail" RELATED []
relationship: part_of BTO:0001277 ! spermatozoon

[Term]
id: BTO:0001273
name: spermatheca
namespace: BrendaTissueOBO
def: "A sac for sperm storage in the female reproductive tract of various lower animals and especially insects." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spermatheca]
synonym: "seminal receptacle" RELATED []
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0001274
name: spermatid
namespace: BrendaTissueOBO
def: "One of the haploid cells that are formed by division of the secondary spermatocytes and that differentiate into spermatozoa." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spermatid]
synonym: "spermatoblast" RELATED []
relationship: DRV BTO:0000709 ! secondary spermatocyte

[Term]
id: BTO:0001275
name: spermatocyte
namespace: BrendaTissueOBO
def: "A cell giving rise to sperm cells; especially: a cell that is derived from a spermatogonium and ultimately gives rise to four haploid spermatids." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spermatocyte]
is_a: BTO:0000535 ! germ cell
relationship: DRV BTO:0000958 ! spermatogonium
relationship: part_of BTO:0001230 ! semen

[Term]
id: BTO:0001276
name: pollen tube
namespace: BrendaTissueOBO
def: "The slender tube formed by the pollen grain that penetrates an ovule and releases the male gametes." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: DRV BTO:0001097 ! pollen

[Term]
id: BTO:0001277
name: spermatozoon
namespace: BrendaTissueOBO
def: "A motile male gamete of an animal usually with rounded or elongate head and a long posterior flagellum." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spermatozoon]
synonym: "sperm cell" RELATED []
is_a: BTO:0000535 ! germ cell
relationship: DRV BTO:0001274 ! spermatid
relationship: part_of BTO:0001230 ! semen

[Term]
id: BTO:0001278
name: spike
namespace: BrendaTissueOBO
def: "An elongated inflorescence similar to a raceme but having the flowers sessile on the main axis." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spike]
synonym: "GRO:0005452" RELATED []
is_a: BTO:0000469 ! flower

[Term]
id: BTO:0001279
name: spinal cord
namespace: BrendaTissueOBO
def: "The cord of nervous tissue that extends from the brain lengthwise along the back in the vertebral canal, gives off the pairs of spinal nerves, carries impulses to and from the brain, and serves as a center for initiating and coordinating many reflex acts." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spinal+cord]
relationship: part_of BTO:0000227 ! central nervous system
relationship: part_of BTO:0000282 ! head

[Term]
id: BTO:0001280
name: spinal fluid
namespace: BrendaTissueOBO
def: "A liquid that is comparable to serum but contains less dissolved material, that is secreted from the blood into the lateral ventricles of the brain by the choroid plexus, circulates through the ventricles to the spaces between the meninges about the brain and spinal cord, and is resorbed into the blood through the subarachnoid sinuses, and that serves chiefly to maintain uniform pressure within the brain and spinal cord." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "cerebrospinal fluid" RELATED []
relationship: DRV BTO:0000089 ! blood
relationship: REL BTO:0000879 ! lateral ventricle

[Term]
id: BTO:0001281
name: spleen
namespace: BrendaTissueOBO
def: "A highly vascular ductless organ that is located in the left abdominal region near the stomach or intestine of most vertebrates and is concerned with final destruction of red blood cells, filtration and storage of blood, and production of lymphocytes." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=spleen]
is_a: BTO:0000753 ! lymphoid tissue
is_a: BTO:0001491 ! viscus

[Term]
id: BTO:0001282
name: HT-1080 cell
namespace: BrendaTissueOBO
def: "Human fibrosarcoma cell line; established from the biopsy from a fibrosarcoma of a 35-year-old Caucasian man in 1972; patient did not receive any chemo- or radiotherapy." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000460 ! fibrosarcoma cell line

[Term]
id: BTO:0001283
name: mitral cell
namespace: BrendaTissueOBO
def: "Mitral cells are the principal relay neurons in the olfactory bulb. At the stages 54-56 the main bulb has approximately 1300 of them. Most of them are located in the dorsal part of the bulb. Its dorsal half contains approximately twice as many mitral cells than the ventral half. The external plexiform layer in front of the mitral cell layer can be identified in the dorsal bulb only, while in the ventral bulb the mitral cells are typically located close to and sometimes within the glomerular layer." [Universität Göttingen \, Physiologisches Institut \, Molekulare Neurophysiologie:http\://www.neuro-physiol.med.uni-goettingen.de/UKMN/content/cont03b2.html]
relationship: part_of BTO:0001108 ! mitral cell layer
relationship: part_of BTO:0001317 ! glomerular layer
relationship: part_of BTO:0003796 ! periglomerular cell

[Term]
id: BTO:0001284
name: femur
namespace: BrendaTissueOBO
def: "The bone that extends from the pelvis to the knee, being the longest and largest bone in the body; its head articulates with the acetabulum of the hip bone, and distally, the femur, along with the patella and tibia, forms the knee joint." [Dorlands Medical Dictionary:MerckSource]
synonym: "femoral bone" RELATED []
synonym: "os femorale" RELATED []
synonym: "os femoris" RELATED []
synonym: "thigh bone" RELATED []
is_a: BTO:0000140 ! bone
relationship: part_of BTO:0002345 ! hindlimb

[Term]
id: BTO:0001285
name: sporangiophore
namespace: BrendaTissueOBO
def: "A stalk or similar structure bearing sporangia." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
is_a: BTO:0000468 ! floret

[Term]
id: BTO:0001286
name: skin cancer cell
namespace: BrendaTissueOBO
def: "The two most common forms of skin cancer are basal cell carcinoma and squamous cell carcinoma. Together, these two are also referred to as nonmelanoma skin cancer. Melanoma is generally the most serious form of skin cancer because it tends to spread (metastasize) throughout the body quickly." [Medical Dictionary:http\://www.medterms.com/]
relationship: DRV BTO:0001253 ! skin

[Term]
id: BTO:0001287
name: sporangium
namespace: BrendaTissueOBO
def: "A structure in which spores are produced." [PAE Virtual Glossary \, \"Plants \, Animals \, and the Environment\" Glossary derived from leading WCB/McGraw-Hill textbooks:http\://www.mhhe.com/biosci/pae/glossary.html]
is_a: BTO:0001285 ! sporangiophore

[Term]
id: BTO:0001288
name: adductor brevis
namespace: BrendaTissueOBO
def: "Adductor arising from the inferior ramus of the pubis and inserted into the iliopectineal line and the upper part of the linea aspera." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000030 ! adductor

[Term]
id: BTO:0001289
name: squamous cell carcinoma cell
namespace: BrendaTissueOBO
def: "Carcinoma developed from squamous epithelium, having cuboid cells and characterized by keratinization and often by preservation of intercellular bridges. Initially local and superficial, the lesion may later invade and metastasize." [Dorlands Medical Dictionary:MerckSource]
synonym: "epidermoid carcinoma cell" RELATED []
synonym: "prickle cell carcinoma cell" RELATED []
relationship: DRV BTO:0002072 ! squamous epithelium

[Term]
id: BTO:0001290
name: sporocarp
namespace: BrendaTissueOBO
def: "A structure (as in red algae, fungi, or mosses) in or on which spores are produced." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sporocarp]
is_a: BTO:0000468 ! floret

[Term]
id: BTO:0001291
name: sporophore
namespace: BrendaTissueOBO
def: "The spore-producing organ of a fungus or slime mold." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sporophore]
synonym: "FAO:0000010" RELATED []
relationship: part_of BTO:0000487 ! fruitbody

[Term]
id: BTO:0001292
name: sporozoite
namespace: BrendaTissueOBO
def: "A usually motile infective form of some sporozoans that is a product of sporogony and initiates an asexual cycle in the new host." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sporozoite]
is_a: BTO:0000749 ! sporozoan

[Term]
id: BTO:0001293
name: sporulated oocyst
namespace: BrendaTissueOBO
def: "A sporozoan zygote undergoing sporogenous development." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sporulated+oocyst]
is_a: BTO:0001773 ! oocyst

[Term]
id: BTO:0001294
name: sporulating cell
namespace: BrendaTissueOBO
is_a: BTO:0001434 ! vegetative cell

[Term]
id: BTO:0001295
name: cranium
namespace: BrendaTissueOBO
def: "1: The skull of a vertebrate.\n2: The portion of the skull enclosing the brain; the braincase." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "skull" RELATED []
is_a: BTO:0000140 ! bone
relationship: part_of BTO:0000282 ! head
relationship: part_of BTO:0003370 ! craniofacial region

[Term]
id: BTO:0001296
name: sprout
namespace: BrendaTissueOBO
def: "A young shoot (as from a seed or root)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sprout]
relationship: part_of BTO:0001228 ! seedling

[Term]
id: BTO:0001297
name: sputum
namespace: BrendaTissueOBO
def: "Matter ejected from the lungs, bronchi, and trachea, through the mouth." [Dorlands Medical Dictionary:MerckSource]
synonym: "expectoration" RELATED []
relationship: DRV BTO:0000136 ! bronchoalveolar system
relationship: DRV BTO:0001090 ! mouth
relationship: DRV BTO:0001388 ! trachea

[Term]
id: BTO:0001298
name: basal cell carcinoma cell
namespace: BrendaTissueOBO
def: "Basal cell carcinoma is the most common form of skin cancer and accounts for more than 90 percent of all skin cancer in the U.S. These cancers almost never spread (metastasize) to other parts of the body. They can, however, cause damage by growing and invading surrounding tissue." [Medical Dictionary:http\://www.medterms.com/]
synonym: "basalioma cell" RELATED []
is_a: BTO:0001286 ! skin cancer cell

[Term]
id: BTO:0001299
name: stele
namespace: BrendaTissueOBO
def: "The usually cylindrical central vascular portion of the axis of a vascular plant." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=stele]
synonym: "GRO:0000314" RELATED []
is_a: BTO:0001429 ! vascular bundle
relationship: part_of BTO:0001188 ! root

[Term]
id: BTO:0001300
name: stem
namespace: BrendaTissueOBO
def: "The main trunk of a plant; specifically: a primary plant axis that develops buds and shoots instead of roots." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=stem]
synonym: "axis" RELATED []
synonym: "culm" RELATED []
synonym: "stalk" RELATED []
relationship: part_of BTO:0001243 ! shoot

[Term]
id: BTO:0001301
name: bark
namespace: BrendaTissueOBO
def: "The tough exterior covering of a woody root or stem; specifically: the tissues outside the cambium that include an inner layer especially of secondary phloem and an outer layer of periderm." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=bark]
is_a: BTO:0001184 ! rind
relationship: part_of BTO:0001188 ! root

[Term]
id: BTO:0001302
name: sternum
namespace: BrendaTissueOBO
def: "A compound ventral bone or cartilage of most vertebrates other than fishes that connects the ribs or the shoulder girdle or both and in humans consists of the manubrium, gladiolus, and xiphoid process." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sternum]
synonym: "breastbone" RELATED []
is_a: BTO:0000140 ! bone

[Term]
id: BTO:0001303
name: stigma
namespace: BrendaTissueOBO
def: "The usually apical part of the pistil of a flower which receives the pollen grains and on which they germinate." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=stigma]
synonym: "GRO:0005433" RELATED []
relationship: part_of BTO:0000072 ! carpel

[Term]
id: BTO:0001304
name: stipe
namespace: BrendaTissueOBO
def: "A usually short plant stalk: as a: the stem supporting the cap of a fungus b: a part that is similar to a stipe and connects the holdfast and blade of a frondose alga c: the petiole of a fern frond d: a prolongation of the receptacle beneath the ovary of a seed plant." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=stipe]
is_a: BTO:0000468 ! floret

[Term]
id: BTO:0001305
name: stipule
namespace: BrendaTissueOBO
def: "Either of a pair of appendages borne at the base of the leaf in many plants" [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=stipule]
synonym: "GRO:0005081" RELATED []
relationship: part_of BTO:0000715 ! leaf base

[Term]
id: BTO:0001306
name: stolon
namespace: BrendaTissueOBO
def: "A horizontal branch from the base of a plant that produces new plants from buds at its tip or nodes (as in the strawberry)." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=stolon]
synonym: "runner" RELATED []
is_a: BTO:0000148 ! branch

[Term]
id: BTO:0001307
name: stomach
namespace: BrendaTissueOBO
def: "A dilatation of the alimentary canal of a vertebrate communicating anteriorly with the esophagus and posteriorly with the duodenum." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=stomach]
synonym: "gaster" RELATED []
relationship: part_of BTO:0000511 ! gastrointestinal tract

[Term]
id: BTO:0001308
name: gastric mucosa
namespace: BrendaTissueOBO
def: "The mucous coat of the stomach." [Dorlands Medical Dictionary:MerckSource]
synonym: "stomach mucosa" RELATED []
synonym: "tunica mucosa gastris" RELATED []
is_a: BTO:0000886 ! mucosa
relationship: part_of BTO:0000024 ! abomasum
relationship: part_of BTO:0001307 ! stomach

[Term]
id: BTO:0001309
name: tuberous root
namespace: BrendaTissueOBO
def: "A thick fleshy storage root like a tuber but lacking buds or scale leaves." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tuberous+root]
synonym: "GRO:0005770" RELATED []
is_a: BTO:0001188 ! root
is_a: BTO:0001310 ! storage tissue

[Term]
id: BTO:0001310
name: storage tissue
namespace: BrendaTissueOBO
relationship: part_of BTO:0001461 ! whole plant

[Term]
id: BTO:0001311
name: corpus striatum
namespace: BrendaTissueOBO
def: "Either of a pair of masses of nervous tissue within the brain that contain two large nuclei of gray matter separated by sheets of white matter." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=corpus+striatum]
synonym: "striatum" RELATED []
relationship: part_of BTO:0000235 ! basal ganglion

[Term]
id: BTO:0001312
name: adductor magnus
namespace: BrendaTissueOBO
def: "Adductor arising from the inferior ramus of the pubis and the ischium and inserted behind the first two into the linea aspera." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000030 ! adductor

[Term]
id: BTO:0001313
name: style
namespace: BrendaTissueOBO
def: "A filiform prolongation of a plant ovary bearing a stigma at its apex." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=style]
relationship: part_of BTO:0000072 ! carpel

[Term]
id: BTO:0001314
name: subcutis
namespace: BrendaTissueOBO
def: "The deeper part of the dermis." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=subcutis]
relationship: part_of BTO:0000294 ! dermis

[Term]
id: BTO:0001315
name: sublingual gland
namespace: BrendaTissueOBO
def: "Gland situated or administered under the tongue; the smallest of the three salivary glands, occurring in pairs, predominantly mucous in type, and draining into the oral cavity through 10 to 30 sublingual ducts." [Dorlands Medical Dictionary:MerckSource, From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sublingual+gland]
synonym: "Rivinus gland" RELATED []
is_a: BTO:0001203 ! salivary gland

[Term]
id: BTO:0001316
name: submandibular gland
namespace: BrendaTissueOBO
def: "One of the three chief, paired salivary glands, predominantly serous, lying partly above and partly below the posterior half of the base of the mandible." [Dorlands Medical Dictionary:MerckSource]
synonym: "submaxillary gland" RELATED []
is_a: BTO:0001203 ! salivary gland

[Term]
id: BTO:0001317
name: glomerular layer
namespace: BrendaTissueOBO
def: "The glomerular layer is the most superficial layer, consisting of mitral cell dendritic arborizations (glomeruli), olfactory nerve fibers, and periglomerular cells. Periglomerular cells contact multiple mitral cell dendrites within the glomeruli and provide lateral inhibition of neighboring glomeruli while allowing excitation of a specific mitral cell dendritic tree. Each mitral cell is contacted by at least 1000 olfactory nerve fibers." [Anatomy of Olfactory System:http\://www.emedicine.com/]
relationship: part_of BTO:0000961 ! olfactory bulb

[Term]
id: BTO:0001318
name: submandibular ganglion
namespace: BrendaTissueOBO
def: "A parasympathetic ganglion located superior to the deep part of the submandibular gland, on the lateral surface of the hyoglossus muscle; its preganglionic fibers are derived from the facial nerve by way of the chorda tympani and lingual nerve, and its postganglionic fibers supply the submandibular and sublingual glands; sensory and postganglionic sympathetic fibers pass through the ganglion." [Dorlands Medical Dictionary:MerckSource]
synonym: "Blandin`s ganglion" RELATED []
synonym: "ganglion submandibulare" RELATED []
synonym: "submaxillary ganglion" RELATED []
is_a: BTO:0001256 ! parasympathetic ganglion

[Term]
id: BTO:0001319
name: external plexiform layer
namespace: BrendaTissueOBO
def: "The external plexiform layer contains the passing dendrites of mitral cells and a few tufted cells, which are similar in size to mitral cells. Some of the granule cell dendrites in the plexiform layer contact mitral cell dendrites through a specialized dendrodendritic synapse, which also is termed a reciprocal synapse.Tufted cells also receive granule cell input through dendrodendritic and dendrosomatic contact." [Anatomy of Olfactory System:http\://www.emedicine.com/]
relationship: part_of BTO:0000961 ! olfactory bulb

[Term]
id: BTO:0001320
name: internal plexiform layer
namespace: BrendaTissueOBO
relationship: part_of BTO:0000961 ! olfactory bulb

[Term]
id: BTO:0001321
name: LNCaP cell
namespace: BrendaTissueOBO
def: "Human prostate carcinoma, established from the left supraclavicular lymph node metastasis from a 50-year-old man with prostate carcinoma in 1977; cells were described to be androgen-sensitive." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "LNCAP cell" RELATED []
is_a: BTO:0001033 ! prostate cancer cell line

[Term]
id: BTO:0001322
name: culture condition:succinate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001323
name: BPH-1 cell
namespace: BrendaTissueOBO
def: "Human benign prostate hyperplasia; prostate epithelial cells from a 68-year-old man with benign prostate hyperplasia; cells were immortalized with SV-40 large T-antigen; cells were described to express cytokeratins 8, 18, and 19 (but not 14) and to metabolize prostatic androgens." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "BPH1 cell" RELATED []
is_a: BTO:0001033 ! prostate cancer cell line

[Term]
id: BTO:0001324
name: culture condition:sulfate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001325
name: superior cervical ganglion
namespace: BrendaTissueOBO
def: "The uppermost ganglion on the sympathetic trunk, lying behind the internal carotid artery and in front of the second and third cervical vertebrae; it gives rise to postganglionic fibers to the heart via cervical cardiac nerves, to the pharyngeal plexus and thence to the larynx and pharynx, and to the head via the external and internal carotid plexuses." [Dorlands Medical Dictionary:MerckSource]
synonym: "ganglion cervicale superius" RELATED []
is_a: BTO:0000113 ! cervical ganglion

[Term]
id: BTO:0001326
name: cholangiocarcinoma cell
namespace: BrendaTissueOBO
def: "An adenocarcinoma arising from the epithelium of the intrahepatic bile ducts, composed of eosinophilic cuboidal or columnar epithelial cells arranged in tubules or acini with abundant fibrous stroma; mucus may be secreted but not bile." [Dorlands Medical Dictionary:MerckSource]
relationship: DRV BTO:0000417 ! bile duct epithelium

[Term]
id: BTO:0001327
name: granule cell layer
namespace: BrendaTissueOBO
def: "The granule cell layer contains multiple small round neurons that lack axons. Long dendritic processes of the neurons reach the more superficial layers and inhibit mitral cells and tufted cells. Small distal processes make contacts with the exiting mitral cell axons." [Anatomy of Olfactory System:http\://www.emedicine.com/]
relationship: part_of BTO:0000961 ! olfactory bulb

[Term]
id: BTO:0001328
name: calvarium
namespace: BrendaTissueOBO
def: "An incomplete skull:especially: the portion of a skull including the braincase and excluding the lower jaw or lower jaw and facial portion." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0001295 ! cranium

[Term]
id: BTO:0001329
name: gastrinoma cell
namespace: BrendaTissueOBO
def: "A tumor cell that secretes gastrin; most are islet cell tumors of non-beta cells in the pancreas, but some are found at sites such as the antrum of the stomach, the hilus of the spleen, or regional lymph nodes. This is the usual cause of Zollinger-Ellison syndrome." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000566 ! pancreatic islet cancer cell

[Term]
id: BTO:0001330
name: hepatoma ascites cell
namespace: BrendaTissueOBO
is_a: BTO:0000608 ! hepatoma cell

[Term]
id: BTO:0001331
name: sweat gland
namespace: BrendaTissueOBO
def: "A simple tubular gland of the skin that secretes perspiration, is widely distributed in nearly all parts of the human skin, and consists typically of an epithelial tube extending spirally from a minute pore on the surface of the skin into the dermis or subcutaneous tissues where it ends in a convoluted tuft." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=sweat+gland]
synonym: "glandula sudorifera" RELATED []
synonym: "sudoriferous gland" RELATED []
synonym: "sudoriparous gland" RELATED []
is_a: BTO:0000431 ! excretory gland
is_a: BTO:0000765 ! exocrine gland

[Term]
id: BTO:0001332
name: DU-145 cell
namespace: BrendaTissueOBO
def: "Human prostate carcinoma, established from the tumor tissue removed from the metastatic central nervous system lesion of a 69-year-old man with prostate carcinoma in 1975." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "DU145 cell" RELATED []
is_a: BTO:0001033 ! prostate cancer cell line

[Term]
id: BTO:0001333
name: sympathetic ganglion
namespace: BrendaTissueOBO
def: "Any of the aggregations of cell bodies of primarily adrenergic neurons of the sympathetic nervous system, including the ganglia of the sympathetic trunks, the intermediate ganglia, the prevertebral ganglia, and some ganglionic cells in the autonomic plexuses." [Dorlands Medical Dictionary:MerckSource]
synonym: "ganglion sympatheticum" RELATED []
synonym: "ganglion sympathicum" RELATED []
is_a: BTO:0000497 ! ganglion
relationship: part_of BTO:0001834 ! sympathetic chain

[Term]
id: BTO:0001334
name: papilloma cell
namespace: BrendaTissueOBO
def: "A cell of small benign epithelial tumor, such as a wart, consisting of an overgrowth of cells on a core of smooth connective tissue." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000415 ! epithelioma cell

[Term]
id: BTO:0001335
name: syncytiotrophoblast
namespace: BrendaTissueOBO
def: "Syncytial layer that forms the outermost fetal layer in the placenta and is thus the interface with maternal tissue. Has invasive capacity - though in a regulated manner." [The Dictionary of Cell and Molecular Biology:Third Edition]
relationship: part_of BTO:0001079 ! trophoblast

[Term]
id: BTO:0001336
name: synovial fibroblast
namespace: BrendaTissueOBO
is_a: BTO:0000452 ! fibroblast
relationship: part_of BTO:0001338 ! synovial tissue

[Term]
id: BTO:0001337
name: extensor digitorum brevis
namespace: BrendaTissueOBO
def: "A muscle on the dorsum of the foot that extends the toes. " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000151 ! extensor
relationship: part_of BTO:0000476 ! foot

[Term]
id: BTO:0001338
name: synovial tissue
namespace: BrendaTissueOBO
def: "Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow." [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
synonym: "synovial cell" RELATED []
is_a: BTO:0001486 ! skeletal system

[Term]
id: BTO:0001339
name: synovia
namespace: BrendaTissueOBO
def: "A transparent viscid lubricating fluid secreted by a membrane of an articulation, bursa, or tendon sheath." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=synovia]
synonym: "synovial fluid" RELATED []
relationship: DRV BTO:0001823 ! synovium

[Term]
id: BTO:0001340
name: bronchus
namespace: BrendaTissueOBO
def: "Either of the two primary divisions of the trachea that lead respectively into the right and the left lung." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=bronchus]
relationship: part_of BTO:0000136 ! bronchoalveolar system

[Term]
id: BTO:0001341
name: S49 cell
namespace: BrendaTissueOBO
def: "Mouse T-lymphocyte, lymphoma cell line." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0003212 ! T-lymphoma cell line

[Term]
id: BTO:0001342
name: A3 cell
namespace: BrendaTissueOBO
def: "Human T lymphocyte, acute T cell leukemia cell line. Morphology: lymphoblastoid. The A3 subclone was derived from a Jurkat cell line obtained from the laboratory of Gerald Crabtree at Stanford University. The Jurkat cells were treated with Fas Antibody and isolated by limiting dilution to obtain a cell line that had a low spontaneous rate of resistance to Fas-medicated apoptosis. The resulting wild-type A3 subclone is very sensitive to Fas-mediated apoptosis. " [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
relationship: DRV BTO:0000661 ! JURKAT cell

[Term]
id: BTO:0001343
name: extensor digitorum communis
namespace: BrendaTissueOBO
def: "A muscle on the back of the forearm that extends the fingers and wrist . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
is_a: BTO:0000151 ! extensor
relationship: part_of BTO:0001447 ! forearm

[Term]
id: BTO:0001344
name: adult T-cell lymphoma cell
namespace: BrendaTissueOBO
def: "A cell of a malignancy of mature T lymphocytes with onset in adulthood, believed to be caused by human T-lymphotropic virus 1 and characterized by circulating pleomorphic malignant lymphocytes, skin lesions, lymphadenopathy, hepatosplenomegaly, hypercalcemia, and lytic bone lesions; its course may be subacute or chronic." [Dorlands Medical Dictionary:MerckSource]
synonym: "adult T-cell leukemia cell" RELATED []
synonym: "ATL cell" RELATED []
is_a: BTO:0001271 ! leukemia cell
is_a: BTO:0001825 ! T-cell lymphoma cell

[Term]
id: BTO:0001345
name: T-24 cell
namespace: BrendaTissueOBO
def: "Human urinary bladder carcinoma, established from the primary tumor of an 81-year-old Caucasian woman with urinary bladder carcinoma (transitional cell carcinoma, grade III) in 1970; described to produce a variety of cytokines (e.g. G-CSF, IL-6 and SCF) and to carry a p53 mutation." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "T24 cell" RELATED []
is_a: BTO:0000792 ! urinary bladder cancer cell line

[Term]
id: BTO:0001346
name: tachyzoite
namespace: BrendaTissueOBO
def: "Oval, quickly multiplying trophozoite of Toxoplasma gondii, found in all tissues except non-nucleated erythrocytes during the acute stage of toxoplasmosis. " [Dorlands Medical Dictionary:MerckSource]
synonym: "endocoite" RELATED []
is_a: BTO:0001397 ! trophozoite

[Term]
id: BTO:0001347
name: tadpole
namespace: BrendaTissueOBO
def: "A larval amphibian; specifically: a frog or toad larva that has a rounded body with a long tail bordered by fins and external gills soon replaced by internal gills and that undergoes a metamorphosis to the adult." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tadpole]
is_a: BTO:0000707 ! larva

[Term]
id: BTO:0001348
name: tail
namespace: BrendaTissueOBO
def: "The rear end or a process or prolongation of the rear end of the body of an animal." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tail]
relationship: part_of BTO:0001493 ! trunk

[Term]
id: BTO:0001349
name: NRP-152 cell
namespace: BrendaTissueOBO
def: "Non-tumorigenic rat prostatic epithelial line." [PMID:12876289]
synonym: "NRP152 cell" RELATED []
is_a: BTO:0001019 ! prostate gland cell line

[Term]
id: BTO:0001350
name: tapetum
namespace: BrendaTissueOBO
def: "A layer of nutritive cells that invests the sporogenous tissue in the sporangium of higher plants." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tapetum]
synonym: "GRO:0005649" RELATED []
relationship: part_of BTO:0001287 ! sporangium

[Term]
id: BTO:0001351
name: vomeronasal nerve
namespace: BrendaTissueOBO
def: "A nerve that exists in the human fetus but disappears before birth, that originates in the olfactory epithelial cells of Jacobson's organ, and that passes through the submucous tissue of the nasal septum and the cribriform plate of the ethmoid bone to the olfactory bulb . " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0000449 ! fetus

[Term]
id: BTO:0001352
name: NRP-154 cell
namespace: BrendaTissueOBO
def: "Rat prostate carcinoma cell line." [PMID:10672898]
synonym: "NRP154 cell" RELATED []
is_a: BTO:0001033 ! prostate cancer cell line

[Term]
id: BTO:0001353
name: telson
namespace: BrendaTissueOBO
def: "The terminal segment of the body of an arthropod or segmented worm; especially: that of a crustacean forming the middle lobe of the tail." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=telson]
relationship: part_of BTO:0001348 ! tail

[Term]
id: BTO:0001354
name: telson muscle
namespace: BrendaTissueOBO
relationship: part_of BTO:0001353 ! telson

[Term]
id: BTO:0001355
name: temporal lobe
namespace: BrendaTissueOBO
def: "One of the two parietal lobes of the brain located behind the frontal lobe at the top of the brain. Parietal Lobe, Right - Damage to this area can cause visuo-spatial deficits (e.g., the patient may have difficulty finding their way around new, or even familiar, places). Parietal Lobe, Left - Damage to this area may disrupt a patient's ability to understand spoken and/or written language. The parietal lobes contain the primary sensory cortex which controls sensation (touch, pressure). Behind the primary sensory cortex is a large association area that controls fine sensation (judgment of texture, weight, size, shape)." [A Guide to Brain Anatomy:http\://www.waiting.com/brainanatomy.html]
synonym: "temporal cortex" RELATED []
relationship: part_of BTO:0000445 ! cerebral lobe

[Term]
id: BTO:0001356
name: tendon
namespace: BrendaTissueOBO
def: "A tough cord or band of dense white fibrous connective tissue that unites a muscle with some other part (as a bone) and transmits the force which the muscle exerts." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tendon]
is_a: BTO:0000421 ! connective tissue
relationship: part_of BTO:0001369 ! vertebrate muscular system

[Term]
id: BTO:0001357
name: tentacle
namespace: BrendaTissueOBO
def: "Any of various elongate flexible usually tactile or prehensile processes borne by animals and especially invertebrates chiefly on the head or about the mouth." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tentacle]
relationship: part_of BTO:0000282 ! head
relationship: part_of BTO:0001090 ! mouth

[Term]
id: BTO:0001358
name: culture condition:terephthalate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001359
name: medulloblastoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000690 ! brain cancer cell line
is_a: BTO:0000711 ! glioma cell line
relationship: DRV BTO:0001757 ! medulloblastoma cell

[Term]
id: BTO:0001360
name: decidua
namespace: BrendaTissueOBO
def: "1: The part of the mucous membrane lining the uterus that in higher placental mammals undergoes special modifications in preparation for and during pregnancy and is cast off at parturition.\n2: The part of the mucous membrane of the uterus cast off in the process of menstruation." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=decidua]
synonym: "uterine decidua" RELATED []
relationship: part_of BTO:0000411 ! cervical mucosa

[Term]
id: BTO:0001361
name: CMT93/69 cell
namespace: BrendaTissueOBO
def: "Mouse C57BL/1CRF rectum carcinoma." [European collection of cell cultures:ECACC]
is_a: BTO:0000297 ! carcinoma cell line
relationship: DRV BTO:0003864 ! CMT-93 cell

[Term]
id: BTO:0001362
name: olfactory lobe
namespace: BrendaTissueOBO
def: "An anterior projection of each cerebral hemisphere that is continuous anteriorly with the olfactory nerve;\nA term applied to the olfactory apparatus on the lower surface of the frontal lobe of the brain. It consists of the olfactory bulb, tract, and trigone." [Dorlands Medical Dictionary:MerckSource, From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=olfactory+lobe]
relationship: part_of BTO:0000484 ! frontal lobe

[Term]
id: BTO:0001363
name: testis
namespace: BrendaTissueOBO
def: "A typically paired male reproductive gland that produces sperm and that in most mammals is contained within the scrotum at sexual maturity." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=testis]
synonym: "orchis" RELATED []
synonym: "testicle" RELATED []
synonym: "testiculus" RELATED []
is_a: BTO:0000080 ! male reproductive gland
is_a: BTO:0003096 ! internal male genital organs

[Term]
id: BTO:0001364
name: testis sheath
namespace: BrendaTissueOBO
relationship: part_of BTO:0001363 ! testis

[Term]
id: BTO:0001365
name: thalamus
namespace: BrendaTissueOBO
def: "The largest subdivision of the diencephalon that consists chiefly of an ovoid mass of nuclei in each lateral wall of the third ventricle and functions in the integration of sensory information." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=thalamus]
relationship: part_of BTO:0000342 ! diencephalon

[Term]
id: BTO:0001366
name: thallus
namespace: BrendaTissueOBO
def: "A plant body that is characteristic of thallophytes , lacks differentiation into distinct members (as stem, leaves, and roots), and does not grow from an apical point." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=thallus]
is_a: BTO:0000720 ! plant form

[Term]
id: BTO:0001367
name: thigh muscle
namespace: BrendaTissueOBO
is_a: BTO:0000722 ! leg muscle

[Term]
id: BTO:0001368
name: thorax
namespace: BrendaTissueOBO
def: "1: The part of the mammalian body between the neck and the abdomen; also: its cavity in which the heart and lungs lie.\n2: The middle of the three chief divisions of the body of an insect; also: the corresponding part of a crustacean or an arachnid." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=thorax]
synonym: "chest" RELATED []
relationship: part_of BTO:0001493 ! trunk

[Term]
id: BTO:0001369
name: vertebrate muscular system
namespace: BrendaTissueOBO
is_a: BTO:0001485 ! muscular system

[Term]
id: BTO:0001370
name: THP-1 cell
namespace: BrendaTissueOBO
def: "Human acute monocytic leukemia established from the peripheral blood of a 1-year-old boy with acute monocytic leukemia (AML) at relapse in 1978; the cells can be used for induction of differentiation studies; the cells were described to produce lysozyme and to be phagocytic." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "THP1 cell" RELATED []
is_a: BTO:0002332 ! monocytic leukemia cell line

[Term]
id: BTO:0001371
name: iris dilator muscle
namespace: BrendaTissueOBO
def: "A name given fibers extending radially from the sphincter pupillae to the ciliary margin; innervation, sympathetic; action, dilates iris." [Dorlands Medical Dictionary:MerckSource]
synonym: "dilator pupillae muscle" RELATED []
synonym: "musculus dilator pupillae" RELATED []
is_a: BTO:0000655 ! iris smooth muscle

[Term]
id: BTO:0001372
name: thymocyte
namespace: BrendaTissueOBO
def: "Lymphocyte within the thymus; term usually applied to an immature lymphocyte." [The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "thymus lymphocyte" RELATED []
is_a: BTO:0001145 ! pre-T-lymphocyte
relationship: part_of BTO:0001374 ! thymus

[Term]
id: BTO:0001374
name: thymus
namespace: BrendaTissueOBO
def: "A glandular structure of largely lymphoid tissue that functions especially in the development of the body's immune system, is present in the young of most vertebrates typically in the upper anterior chest or at the base of the neck, and tends to atrophy in the adult." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=thymus]
is_a: BTO:0000753 ! lymphoid tissue
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0001368 ! thorax

[Term]
id: BTO:0001375
name: mandibular nerve
namespace: BrendaTissueOBO
def: "One of three terminal divisions of the trigeminal nerve, passing through the foramen ovale to the infratemporal fossa. Origin, trigeminal ganglion; branches, meningeal ramus, masseteric, deep temporal, lateral and medial pterygoid, buccal, auriculotemporal, lingual, and inferior alveolar nerves; distribution, extensive distribution to muscles of mastication, skin of face, mucous membrane of mouth, and teeth." [Dorlands Medical Dictionary:MerckSource]
synonym: "nervus mandibularis" RELATED []
relationship: part_of BTO:0001072 ! trigeminal nerve

[Term]
id: BTO:0001376
name: thigh
namespace: BrendaTissueOBO
def: "1: The proximal segment of the vertebrate hind limb extending from the hip to the knee and supported by a single large bone. \n2: The segment of the leg immediately distal to the thigh in a bird or in a quadruped in which the true thigh is obscured." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=thigh]
relationship: part_of BTO:0000721 ! leg

[Term]
id: BTO:0001377
name: thymus lymphoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000104 ! lymphoma cell line

[Term]
id: BTO:0001378
name: maxillary nerve
namespace: BrendaTissueOBO
def: "One of the three terminal divisions of the trigeminal nerve, passing through the foramen rotundum, and entering the pterygopalatine fossa. Origin, trigeminal ganglion; branches, meningeal ramus, zygomatic nerve, posterior superior alveolar rami, infraorbital nerve, pterygopalatine nerves, and, indirectly, the branches of the pterygopalatine ganglion; distribution, extensive distribution to skin of face and scalp, mucous membrane of maxillary sinus and nasal cavity, and teeth." [Dorlands Medical Dictionary:MerckSource]
synonym: "nervus maxillaris" RELATED []
relationship: part_of BTO:0001072 ! trigeminal nerve

[Term]
id: BTO:0001379
name: thyroid gland
namespace: BrendaTissueOBO
def: "A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "thyroid" RELATED []
is_a: BTO:0001488 ! endocrine gland
relationship: part_of BTO:0000828 ! throat

[Term]
id: BTO:0001380
name: mesentery
namespace: BrendaTissueOBO
def: "One or more vertebrate membranes that consist of a double fold of the peritoneum and invest the intestines and their appendages and connect them with the dorsal wall of the abdominal cavity." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=mesentery]
relationship: part_of BTO:0001472 ! peritoneum

[Term]
id: BTO:0001381
name: tibial chondrocyte
namespace: BrendaTissueOBO
def: "Chondrocyte pertaining to the tibia." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000207 ! tibial cartilage
is_a: BTO:0000249 ! chondrocyte

[Term]
id: BTO:0001382
name: tibialis anterior
namespace: BrendaTissueOBO
def: "A muscle arising chiefly from the lateral condyle and part of the shaft of the tibia, inserting by a long tendon into the first cuneiform and first metatarsal bones, and acting to flex the foot dorsally and to invert it." [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
synonym: "anterior tibialis" RELATED []
synonym: "ibialis anticus" RELATED []
synonym: "tibialis anterior muscle" RELATED []
is_a: BTO:0000864 ! tibialis

[Term]
id: BTO:0001383
name: alveolar bone
namespace: BrendaTissueOBO
def: "The thin layer of bone making up the bony processes of the maxilla and mandible, and surrounding and containing the teeth; it is pierced by many small openings through which blood vessels, lymphatics, and nerve fibers pass." [Dorlands Medical Dictionary:MerckSource]
relationship: part_of BTO:0000379 ! embryo

[Term]
id: BTO:0001384
name: tissue culture
namespace: BrendaTissueOBO
def: "Growing plant or animal tissues outside of the body, as in a nutrient medium in a laboratory; similar to cell culture, but cells are maintained in their structured, tissue form." [Glossary of Fermentation & Cell Culture Terms:http\://www.nbsc.com/files/papers/bp0600_gloss_36-44.pdf]
is_a: BTO:0000214 ! cell culture

[Term]
id: BTO:0001385
name: tongue
namespace: BrendaTissueOBO
def: "A fleshy movable process of the floor of the mouths of most vertebrates that bears sensory end organs and small glands and functions especially in taking and swallowing food and in humans as a speech organ." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tongue]
is_a: BTO:0000202 ! sense organ
relationship: part_of BTO:0001090 ! mouth

[Term]
id: BTO:0001386
name: tongue muscle
namespace: BrendaTissueOBO
is_a: BTO:0000021 ! head muscle
relationship: part_of BTO:0001385 ! tongue

[Term]
id: BTO:0001387
name: tonsil
namespace: BrendaTissueOBO
def: "Either of a pair of prominent masses of lymphoid tissue that lie one on each side of the throat between the anterior and posterior pillars of the fauces." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tonsil]
relationship: part_of BTO:0000828 ! throat

[Term]
id: BTO:0001388
name: trachea
namespace: BrendaTissueOBO
def: "1: The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi. It is kept patent by a series of about twenty transverse horseshoe-shaped cartilages. Called also windpipe.  \n2: One of a system of minute tubes ramifying throughout the body of a terrestrial arthropod and delivering air to the tissues. Called also tracheal tubule." [Dorlands Medical Dictionary:MerckSource]
synonym: "tracheal tubule" RELATED []
synonym: "windpipe" RELATED []
is_a: BTO:0000203 ! respiratory system

[Term]
id: BTO:0001389
name: tracheal epithelium
namespace: BrendaTissueOBO
is_a: BTO:0000416 ! epithelium
is_a: BTO:0000419 ! respiratory epithelium
relationship: part_of BTO:0001388 ! trachea

[Term]
id: BTO:0001390
name: tracheal mucosa
namespace: BrendaTissueOBO
def: "The tracheal mucosa is columnar and ciliated. It is closely applied to the tracheal cartilages and to the interannular tissues between them. Mucous glands are liberally present." [eMedicine \, Daley B.J. \, Tracheal Tumors:http\://www.emedicine.com/med/topic2975.htm]
is_a: BTO:0000973 ! respiratory mucosa
relationship: part_of BTO:0001388 ! trachea

[Term]
id: BTO:0001391
name: tracheal smooth muscle
namespace: BrendaTissueOBO
is_a: BTO:0001660 ! respiratory smooth muscle
relationship: part_of BTO:0001388 ! trachea

[Term]
id: BTO:0001392
name: culture condition:trans-aconitate-grown cell
namespace: BrendaTissueOBO
is_a: BTO:0001479 ! culture condition:-grown cell

[Term]
id: BTO:0001393
name: mesenchyme
namespace: BrendaTissueOBO
def: "The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
relationship: part_of BTO:0000839 ! mesoderm

[Term]
id: BTO:0001394
name: trapping leaf
namespace: BrendaTissueOBO
is_a: BTO:0000713 ! leaf

[Term]
id: BTO:0001395
name: trichome
namespace: BrendaTissueOBO
def: "A filamentous outgrowth; especially: an epidermal hair structure on a plant." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=trichome]
relationship: part_of BTO:0000718 ! leaf epidermis

[Term]
id: BTO:0001396
name: trophosome tissue
namespace: BrendaTissueOBO
def: "Various chemolithotrophs have been found to live in symbiotic association with animals of the thermal vents. E.g., the 2-m-long tube worms lack a mouth, gut or anus but contain a modified gastrointestinal tract consisting of spongy tissue called the trophosome.  Making up about 50% of the weight of the worm, trophosome tissue is loaded with sulfur granules and large numbers of symbiotic prokaryotic cells (ave. of 4 X 109 cells per g of trophosome tissue.)  Trophosome tissue also shows activity of the enzyme RubisCO and other enzymes of the Calvin cycle, the pathway by which most autotrophic organisms fix CO2 into cellular material." [Colby College \, Department of Biology:http\://www.colby.edu/biology/BI163/HydrothermNOTES.doc]
is_a: BTO:0000058 ! alimentary canal

[Term]
id: BTO:0001397
name: trophozoite
namespace: BrendaTissueOBO
def: "A protozoan, especially of the class Sporozoa, in the active stage of its life cycle." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
is_a: BTO:0000749 ! sporozoan

[Term]
id: BTO:0001398
name: trypomastigote
namespace: BrendaTissueOBO
def: "Any of the bodies representing the morphologic (trypanosomal) stage in the life cycle of certain trypanosomatid protozoa, resembling the typical adult form of members of the genus Trypanosoma, in which the slender elongate cell has a kinetoplast and basal body located at the posterior end and a flagellum running anteriorly along an undulating membrane to become a free-flowing structure. " [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000092 ! trypanosome

[Term]
id: BTO:0001399
name: Tay-Sachs disease specific cell type
namespace: BrendaTissueOBO
def: "Tay-Sachs disease is a lysosomal disease (lipidosis) in which hexosaminidase A, an enzyme that degrades ganglioside GM2, is absent. A hereditary disease that affects young children almost exclusively of eastern European Jewish descent, in which an enzyme deficiency leads to the accumulation of gangliosides in the brain and nerve tissue, resulting in mental retardation, convulsions, blindness, and, ultimately, death." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000., The Dictionary of Cell and Molecular Biology:Third Edition]
synonym: "TSD cell" RELATED []
relationship: REL BTO:0000497 ! ganglion

[Term]
id: BTO:0001400
name: tuber
namespace: BrendaTissueOBO
def: "A short fleshy usually underground stem bearing minute scale leaves each of which bears a bud in its axil and is potentially able to produce a new plant." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=tuber]
is_a: BTO:0001300 ! stem

[Term]
id: BTO:0001401
name: tuber cortex
namespace: BrendaTissueOBO
relationship: part_of BTO:0001400 ! tuber

[Term]
id: BTO:0001402
name: urogenital ridge
namespace: BrendaTissueOBO
def: "A pair of dorsolateral mesodermal ridges in the vertebrate embryo out of which the urogenital organs are developed. " [Fast Health Medical Dictionary:http\://www.fasthealth.com/dictionary/]
relationship: part_of BTO:0000839 ! mesoderm

[Term]
id: BTO:0001403
name: gastrula
namespace: BrendaTissueOBO
def: "An early metazoan embryo in which the ectoderm, mesoderm, and endoderm are established either by invagination of the blastula (as in fish and amphibians) to form a multilayered cellular cup with a blastopore opening into the archenteron or by differentiation of the blastodisc (as in reptiles, birds, and mammals) and inward cellular migration." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=gastrula]
relationship: DRV BTO:0000128 ! blastula
relationship: DRV BTO:0001504 ! blastodisc

[Term]
id: BTO:0001404
name: Yoshida ascites hepatoma cell line
namespace: BrendaTissueOBO
is_a: BTO:0000582 ! hepatoma ascites cell line

[Term]
id: BTO:0001405
name: bronchial cancer cell
namespace: BrendaTissueOBO
relationship: DRV BTO:0001340 ! bronchus

[Term]
id: BTO:0001406
name: HT-144 cell
namespace: BrendaTissueOBO
def: "Homo sapiens (human), morphology: fibroblast, tissue: metastatic site: subcutaneous tissue malignant melanoma, established from a 29-year-old caucasian men." [ATCC American Cell Type Culture Collection:http\://www.lgcstandards-atcc.org/]
is_a: BTO:0000849 ! melanoma cell line

[Term]
id: BTO:0001407
name: neuroendocrine tumor cell
namespace: BrendaTissueOBO
def: "A cell of any of a diverse group of tumors containing neurosecretory cells that cause endocrine dysfunction; most are carcinoids or carcinomas. They occur most often in the gastrointestinal tract, in bronchial and tracheal mucous membranes, and in teratoid ovarian tumors." [Dorlands Medical Dictionary:MerckSource]
is_a: BTO:0000729 ! carcinoid cell
relationship: DRV BTO:0002691 ! neuroendocrine cell

[Term]
id: BTO:0001408
name: locus ceruleus
namespace: BrendaTissueOBO
synonym: "locus caeruleus" RELATED []
synonym: "locus cinereus" RELATED []
synonym: "locus coeruleus" RELATED []
relationship: part_of BTO:0000146 ! brain stem

[Term]
id: BTO:0001409
name: ureter
namespace: BrendaTissueOBO
def: "The tube that carries urine from the kidney to the bladder. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
relationship: part_of BTO:0001244 ! urinary tract
relationship: part_of BTO:0003092 ! urinary system

[Term]
id: BTO:0001410
name: GH3 cell
namespace: BrendaTissueOBO
def: "Rat pituitary tumor, derived in 1965 from a pituitary tumor induced in a female Wistar/Furth rat ollowing repeated transplantation with the MtT/W5 tumor (originally induced in a female F/Fu rat by cranial X-irradiation)." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
is_a: BTO:0000756 ! pituitary gland tumor cell line

[Term]
id: BTO:0001411
name: twig
namespace: BrendaTissueOBO
def: "A small shoot or branch usually without its leaves." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=twig]
is_a: BTO:0001243 ! shoot

[Term]
id: BTO:0001412
name: U-937 cell
namespace: BrendaTissueOBO
def: "Human histiocytic lymphoma established from the pleural effusion of a 37-year-old man with generalized diffuse histiocytic lymphoma in 1974; cells were described to express markers and properties of monocytes; patented cell line." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "U937 cell" RELATED []
is_a: BTO:0000104 ! lymphoma cell line

[Term]
id: BTO:0001413
name: primary cell
namespace: BrendaTissueOBO
def: "A cell taken directly from a living organism, which is not immortalized. " [Northwestern University \, The Department of Biochemistry \, Molecular Biology and Cell Biology (BMBCB):http\://www.biochem.northwestern.edu/holmgren/Glossary/Definitions/Def-P/primary_cell.html]
is_a: BTO:0002322 ! cell property
relationship: part_of BTO:0001127 ! primary culture
relationship: part_of BTO:0001489 ! whole body

[Term]
id: BTO:0001414
name: umbilical vein epithelium
namespace: BrendaTissueOBO
is_a: BTO:0000416 ! epithelium
is_a: BTO:0001509 ! umbilical vein
is_a: BTO:0001847 ! umbilical smooth muscle

[Term]
id: BTO:0001415
name: umbilical cord
namespace: BrendaTissueOBO
def: "A cord arising from the navel that connects the fetus with the placenta; also: yolk stalk" [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=umbilical+cord]
relationship: part_of BTO:0000449 ! fetus
relationship: part_of BTO:0001078 ! placenta

[Term]
id: BTO:0001416
name: umbilical vein endothelium
namespace: BrendaTissueOBO
synonym: "umbilical vein endothelial cell" RELATED []
is_a: BTO:0000393 ! endothelium
relationship: part_of BTO:0001509 ! umbilical vein

[Term]
id: BTO:0001417
name: uredospore
namespace: BrendaTissueOBO
def: "One of the thin-walled spores that are produced by the uredinial hyphae of rust fungi and spread the fungus vegetatively." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=uredospore]
synonym: "FAO:0000026" RELATED []
is_a: BTO:0001171 ! spore
relationship: DRV BTO:0000612 ! hypha

[Term]
id: BTO:0001418
name: urinary bladder
namespace: BrendaTissueOBO
def: "A membranous sac in many vertebrates that serves for the temporary retention of urine and discharges by the urethra." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=urinary+bladder]
synonym: "vesica" RELATED []
is_a: BTO:0000123 ! bladder
relationship: part_of BTO:0001244 ! urinary tract
relationship: part_of BTO:0003092 ! urinary system

[Term]
id: BTO:0001419
name: urine
namespace: BrendaTissueOBO
def: "Waste material that is secreted by the kidney in vertebrates, is rich in end products of protein metabolism together with salts and pigments, and forms a clear amber and usually slightly acid fluid in mammals but is semisolid in birds and reptiles." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=urine]
relationship: DRV BTO:0000671 ! kidney

[Term]
id: BTO:0001420
name: uropygial gland
namespace: BrendaTissueOBO
def: "A large gland at the base of a bird's tail that secretes an oil used in preening." [The American Heritage® Dictionary of the English Language:Fourth Edition. 2000.]
synonym: "oil gland" RELATED []
is_a: BTO:0000765 ! exocrine gland
relationship: part_of BTO:0001348 ! tail

[Term]
id: BTO:0001421
name: uterine cervix
namespace: BrendaTissueOBO
def: "A constricted portion of an organ or part; especially: the narrow outer end of the uterus." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=cervix]
synonym: "cervix" RELATED []
relationship: part_of BTO:0001424 ! uterus

[Term]
id: BTO:0001422
name: uterine endometrium
namespace: BrendaTissueOBO
def: "The mucous membrane lining the uterus." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=endometrium]
synonym: "endometrium" RELATED []
relationship: part_of BTO:0001424 ! uterus

[Term]
id: BTO:0001423
name: uterine lavage
namespace: BrendaTissueOBO
def: "A uterine lavage is a aseptic procedure whereby a sterile solution, usually physiologic saline is infused into the uterus and then allowed to flow out via a sterile catheter placed through the mare's cervix." [Dr. Jon's Breeders' Notebook \, Milfer Farm Inc.:http\://www.milferfarms.com/notebook/week26.htm]
relationship: REL BTO:0001424 ! uterus

[Term]
id: BTO:0001424
name: uterus
namespace: BrendaTissueOBO
def: "An organ of the female mammal for containing and usually for nourishing the young during development previous to birth." [From Merriam-Webster's Online Dictionary at www.Merriam-Webster.com:http\://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=uterus]
synonym: "womb" RELATED []
is_a: BTO:0003099 ! internal female genital organ
relationship: part_of BTO:0000083 ! female reproductive system

[Term]
id: BTO:0001425
name: V-79 cell
namespace: BrendaTissueOBO
def: "Chinese hamster lung fibroblast cell line, established from the lung tissue of a Chinese hamster in 1958." [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH:DSMZ]
synonym: "V79 cell" RELATED []
is_a: BTO:0000161 ! lung fibroblast cell line
is_a: BTO:0000353 ! lung cell line

[Term]
id: BTO:0001426
name: urethra
namespace: BrendaTissueOBO
def: "The tube through which urine leaves the body. It empties urine from the bladder. " [Cancer.gov Dictionary:http\://www.nci.nih.gov/dictionary]
is_a: BTO:0003097 ! external male genital organ
is_a: BTO:0003100 ! external female genital organ
relationship: part_of BTO:0001244 ! urinary tract
relationship: part_of BTO:0003092 ! urinary system

[Term]
id: BTO:0001427
name: vas deferens
namespace: BrendaTissueOBO
def: "A spermatic duct especially of a higher vertebrate that in the human male is a thick-walled tube about two feet (0.61 meters) long that begins at and is continuous with the tail of the epididymis and eventually joins the duct of the seminal vesicle to form the ejaculatory duct." [From Merriam-Webster