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Gene ontology
Version 2014-12-22
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Details for histone demethylase activity (H3-K36 specific)
1.14.11.27
Gene ontology ID
GO:0051864
Definition
Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein
Synonyms
1. [histone-H3]-lysine-36 demethylase activity
2. H3-K36-specific demethylase activity
3. histone H3-lysine-36 demethylase activity
4. histone-lysine (H3-K36) demethylase activity
5. histone-lysine demethylase activity (H3-K36 specific)
6. histone-lysine(H3-K36) demethylase activity
7. JHDM1A activity
8. JmjC domain-containing histone demethylase 1A activity
9. protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity
10. protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity
References
1. PMID 16362057
2. EC 1.14.11.27
3. MetaCyc RXN-8660
4. MetaCyc RXN-8661
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