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Gene ontology
Version 2014-12-22
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Details for glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
2.4.1.224
Gene ontology ID
GO:0050508
Definition
Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP
Synonyms
1. alpha-N-acetylglucosaminyltransferase II activity
2. glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity
3. glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase activity
4. UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
References
1. EC 2.4.1.224
2. MetaCyc 2.4.1.224-RXN
3. Reactome: R-HSA-2022851 "EXT1:EXT2 transfer GlcNAc to the heparan chain"
4. Reactome: R-HSA-2022919 "EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue"
5. Reactome: R-HSA-3656254 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain"
6. Reactome: R-HSA-3656261 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain"
7. Reactome: R-HSA-9036283 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the terminal GlcA residue"
8. Reactome: R-HSA-9036290 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to heparan"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
transferase activity is a
transferase activity, transferring glycosyl groups is a
transferase activity, transferring hexosyl groups is a
acetylglucosaminyltransferase activity is a
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
Atg8 ligase activity is a
CDP-alcohol phosphotransferase activity is a
glucanosyltransferase activity is a
Kdo transferase activity is a
mannosylphosphate transferase activity is a
molybdopterin molybdotransferase activity is a
transferase activity, transferring acyl groups is a
transferase activity, transferring aldehyde or ketonic groups is a
transferase activity, transferring alkyl or aryl (other than methyl) groups is a
transferase activity, transferring glycosyl groups is a
lipopolysaccharide heptosyltransferase activity is a
transferase activity, transferring hexosyl groups is a
(+)-secoisolariciresinol glucosyltransferase activity is a
(+)-secoisolariciresinol monoglucoside glucosyltransferase activity is a
(+)-sesaminol 2-O-glucosyltransferase activity is a
1,2-rhamnosyltransferase activity is a
1,3-beta-D-glucan phosphorylase activity is a
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity is a
1,3-beta-oligoglucan phosphorylase activity is a
1,4-alpha-glucan branching enzyme activity is a
1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) is a
1,4-alpha-oligoglucan phosphorylase activity is a
16-alpha-hydroxygypsogenate-UDP-glucosyltransferase activity is a
19-O-beta-glucopyranosyl-steviol glucosyltransferase activity is a
2'4'6'34-pentahydroxychalcone 4'-O-glucosyltransferase activity is a
2,5-DHBA UDP-glucosyltransferase activity is a
2-deoxystreptamine glucosyltransferase activity is a
2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity is a
3-hydroxyacyl-CoA-acyl carrier protein transferase activity is a
4-acetamido-4,6-dideoxy-D-galactose transferase activity is a
6-hydroxyflavone-glucosyltransferase activity is a
6C-naringenin dibenzoylmethane tautomer glucosyltransferase activity is a
7-deoxyloganetic acid glucosyltransferase activity is a
7-hydroxyflavone-glucosyltransferase activity is a
8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity is a
abequosyltransferase activity is a
acetylgalactosaminyltransferase activity is a
acetylglucosaminyltransferase activity is a
beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity is a
beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity is a
chitin synthase activity is a
dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity is a
galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity is a
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity is a
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity is a
heparan sulfate N-acetylglucosaminyltransferase activity is a
high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity is a
lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity is a
mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity is a
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity is a
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity is a
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity is a
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity is a
phosphatidylinositol N-acetylglucosaminyltransferase activity is a
poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity is a
steroid N-acetylglucosaminyltransferase activity is a
UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity is a
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity is a
ajugose synthase activity is a
alginate synthase activity is a
alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity is a
alpha-1,3-glucan synthase activity is a
alpha-1,4-glucan synthase activity is a
amylosucrase activity is a
anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity is a
anthocyanidin-3-glucoside rhamnosyltransferase activity is a
apigenin-7-O-glucoside 1,6-glucosyltransferase activity is a
apigeninidin 5-O-glucosyltransferase activity is a
baicalein 7-O-glucuronosyltransferase activity is a
benzyladenine UDP glycosyltransferase activity is a
beta,beta digalactosyldiacylglycerol galactosyltransferase activity is a
beta-chaconine rhamnosyltransferase activity is a
beta-maltose 4-alpha-glucanotransferase activity is a
beta-solanine rhamnosyltransferase activity is a
betanidin 5-O-glucosyltransferase activity is a
betanidin 6-O-glucosyltransferase activity is a
brassicasterol glucosyltransferase activity is a
brassinolide 23-O-glucosyltransferase activity is a
castasterone 23-O-glucosyltransferase activity is a
cellodextrin phosphorylase activity is a
cholesterol alpha-glucosyltransferase activity is a
cis-zeatin UDP glycosyltransferase activity is a
curcumin-4'-O-beta-D-gentiobioside 1,6-glucosyltransferase activity is a
curcumin-4'-O-beta-D-gentiotrioside 1,6-glucosyltransferase activity is a
cyanidin 3-O-galactosyltransferase activity is a
cyanidin 3-O-glucoside 2''-O-glucosyltransferase activity is a
cyanidin 3-O-glucoside 5-O glucosyltransferase (vanilloyl-glucose dependent) activity is a
cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity is a
cyanidin 3-O-glucoside 5-O-glucosyltransferase (sinapoyl-glucose dependent) activity is a
cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity is a
cyanidin 3-O-glucoside 7-O-glucosyltransferase (hydroxybenzoly-glucose dependent) activity is a
cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity is a
cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity is a
cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucosyltransferase activity 5-O-glucosyltransferase activity is a
cyanidin 5,3-O-glycosyltransferase activity is a
cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity is a
cyclomaltodextrin glucanotransferase activity is a
D-inositol-3-phosphate glycosyltransferase activity is a
daphnetin 3-O-glucosyltransferase activity is a
daphnetin 4-O-beta-glucosyltransferase activity is a
decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity is a
delphinidin 3-O-glucoside 2''-O-glucosyltransferase activity is a
delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity is a
delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity is a
delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity is a
delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity is a
dextransucrase activity is a
dextrin dextranase activity is a
diglucosyl diacylglycerol synthase activity is a
dihydroceramide glucosyltransferase activity is a
dihydrozeatin UDP glycosyltransferase activity is a
eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity is a
eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity is a
esculetin 3-O-glucosyltransferase activity is a
esculetin 4-O-beta-glucosyltransferase activity is a
esculetin glucosyltransferase activity is a
flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity is a
flavonol-3-O-glucoside L-rhamnosyltransferase activity is a
fructosyltransferase activity is a
galactosylononitol-raffinose galactosyltransferase activity is a
galactosyltransferase activity is a
GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity is a
genistein-3-O-glucoside 1,6-glucosyltransferase activity is a
glucosyltransferase activity is a
glucuronosyltransferase activity is a
gypsogenate-UDP-glucosyltransferase activity is a
gypsogenin-UDP-glucosyltransferase activity is a
hyaluronan synthase activity is a
inositol phosphoceramide synthase activity is a
inositol phosphorylceramide mannosyltransferase activity is a
inulosucrase activity is a
isopentenyladenine UDP glycosyltransferase activity is a
kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity is a
kaempferol 3-glucoside 7-O-rhamnosyltransferase activity is a
kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity is a
kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity is a
kaempferol-3-glucoside-glucosyltransferase activity is a
kaempferol-3-O-glucoside 1,6-glucosyltransferase activity is a
kaempferol-3-rhamnoside-glucosyltransferase activity is a
kinetin UDP glycosyltransferase activity is a
laminaribiose phosphorylase activity is a
levansucrase activity is a
linamarin synthase activity is a
linear malto-oligosaccharide phosphorylase activity is a
lipid-A-disaccharide synthase activity is a
lipopolysaccharide N-acetylmannosaminouronosyltransferase activity is a
luteolin C-glucosyltransferase activity is a
luteolin-7-O-glucoside 1,6-glucosyltransferase activity is a
luteolinidin 5-O-glucosyltransferase activity is a
maltose synthase activity is a
mannosyl-3-phosphoglycerate synthase activity is a
mannosylfructose-phosphate synthase activity is a
mannosylglycerate synthase activity is a
medicagenate UDP-glucosyltransferase activity is a
myricetin 3-O-glucosyltransferase activity is a
myricetin-3-O-glucoside 1,6-glucosyltransferase activity is a
N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity is a
N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity is a
naringenin chalcone 4'-O-glucosyltransferase activity is a
O antigen polymerase activity is a
oligosaccharyl transferase activity is a
pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity is a
pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity is a
pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity is a
pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity is a
peptidoglycan glycosyltransferase activity is a
phenanthrol glycosyltransferase activity is a
phosphatidylinositol alpha-mannosyltransferase activity is a
polygalacturonate 4-alpha-galacturonosyltransferase activity is a
quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity is a
quercetin 3-glucoside 7-O-rhamnosyltransferase activity is a
quercetin 3-O-beta:-D-galactosyltransferase activity is a
quercetin 3-O-rhamnoside-glucosyltransferase activity is a
quercetin 3-rhamnoside 7-O-rhamnosyltransferase activity is a
quercetin 3-sophoroside 7-O-rhamnosyltransferase activity is a
quercetin gentiobioside 1,6-glucosyltransferase activity is a
quercetin gentiotrioside 1,6-glucosyltransferase activity is a
quercetin-3,4'-O-glucosyltransferase activity is a
quercetin-3-O-glucoside 1,6-glucosyltransferase activity is a
quercetin-4',3-O-glucosyltransferase activity is a
rebaudioside B glucosyltransferase activity is a
scutellarein 7-O-glucuronosyltransferase activity is a
sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity is a
sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity is a
SHG alpha-glucan phosphorylase activity is a
soladodine glucosyltransferase activity is a
solanidine glucosyltransferase activity is a
solanine UDP-galactose galactosyltransferase activity is a
soyasapogenol B glucuronide galactosyltransferase activity is a
soyasapogenol B glucuronosyltransferase activity is a
soyasapogenol B UDP-glucosyl transferase activity is a
soyasapogenol E UDP-glucosyltransferase activity is a
soyasaponin III rhamnosyltransferase activity is a
stachyose galactinol:verbascose galactosyltransferase activity is a
stachyose synthase activity is a
steviol 13-O glucosyltransferase activity is a
steviol 19-O glucosyltransferase activity is a
steviolbioside glucosyltransferase activity (rebaudioside B forming) is a
steviolbioside glucosyltransferase activity (stevioside forming) is a
steviolmonoside glucosyltransferase activity is a
stevioside glucosyltransferase activity (rebaudioside A forming) is a
trans-zeatin-O-glucoside UDP glycosyltransferase activity is a
trehalose synthase activity is a
UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity is a
UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity is a
UDP-D-glucose:cyanidin 5-O-beta-D-glucosyltransferase activity is a
UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity is a
UDP-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase activity is a
UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity is a
UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity is a
UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity is a
UDP-glucose: N-methylanthranilate glucosyltransferase activity is a
UDP-glucose:2-hydroxylamino-4,6-dinitrotoluene-O-glucosyltransferase activity is a
UDP-glucose:4-hydroxylamino-2,6-dinitrotoluene-O-glucosyltransferase activity is a
UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity is a
UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity is a
UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity is a
UDP-glucose:benzyladenine 7-N-glucosyltransferase activity is a
UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity is a
UDP-glucose:coniferaldehyde 4-beta-D-glucosyltransferase activity is a
UDP-glucose:curcumin glucosyltransferase activity is a
UDP-glucose:curcumin monoglucoside glucosyltransferase activity is a
UDP-glucose:dihydrozeatin 7-N-glucosyltransferase activity is a
UDP-glucose:isopentenyladenine 7-N-glucosyltransferase activity is a
UDP-glucose:kinetin 7-N-glucosyltransferase activity is a
UDP-glucose:sinapaldehyde 4-beta-D-glucosyltransferase activity is a
UDP-glucose:trans-zeatin 7-N-glucosyltransferase activity is a
UDP-glucose:trans-zeatin 9-N-glucosyltransferase is a
UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase activity is a
UDP-L-rhamnose:quercetin 3-O-rhamnosyltransferase activity is a
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity is a
UDPG:cyclo-DOPA 5-O-glucosyltransferase activity is a
verbascose galactinol:ajugose galactosyltransferase activity is a
verbascose synthase activity is a
wogonin 7-O-glucosyltransferase activity is a
wogonin 7-O-glucuronosyltransferase activity is a
transferase activity, transferring pentosyl groups is a
UDP-glycosyltransferase activity is a
transferase activity, transferring nitrogenous groups is a
transferase activity, transferring one-carbon groups is a
transferase activity, transferring phosphorus-containing groups is a
transferase activity, transferring selenium-containing groups is a
transferase activity, transferring sulfur-containing groups is a
UDP-L-rhamnose synthase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a