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Gene ontology
Version 2014-12-22
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Details for glutathione peroxidase activity
1.11.1.9
Gene ontology ID
GO:0004602
Definition
Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O
Synonyms
1. glutathione:hydrogen-peroxide oxidoreductase activity
2. GSH peroxidase activity
3. non-selenium glutathione peroxidase activity
4. reduced glutathione peroxidase activity
5. selenium-glutathione peroxidase activity
References
1. EC 1.11.1.9
2. MetaCyc GLUTATHIONE-PEROXIDASE-RXN
3. Reactome: R-HSA-2161791 "15S-HpETE is reduced to 15S-HETE by GPX1/2/4"
4. Reactome: R-HSA-2161946 "5S-HpETE is reduced to 5S-HETE by GPX1/2/4"
5. Reactome: R-HSA-2161959 "12R-HpETE is reduced to 12R-HETE by GPX1/2/4"
6. Reactome: R-HSA-2161999 "12S-HpETE is reduced to 12S-HETE by GPX1/2/4"
7. Reactome: R-HSA-3323013 "GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O"
8. Reactome: R-HSA-3341277 "GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O"
9. Reactome: R-HSA-3341397 "GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O"
10. Reactome: R-HSA-3343700 "PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O"
11. Reactome: R-HSA-6799695 "GPX5,6 reduce H2O2 to H2O"
12. Reactome: R-HSA-71676 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O"
13. RHEA: 16833
Legend
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Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular detoxification is a
cellular oxidant detoxification is a
antioxidant activity part of
peroxidase activity is a
glutathione peroxidase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular detoxification of aldehyde is a
cellular detoxification of cadmium ion is a
cellular detoxification of copper ion is a
cellular detoxification of fluoride is a
cellular detoxification of nitrogen compound is a
cellular oxidant detoxification is a
antioxidant activity part of
glutathione dehydrogenase (ascorbate) activity is a
glutathione-disulfide reductase activity is a
peroxidase activity is a
bromide peroxidase activity is a
catalase activity is a
chloride peroxidase activity is a
cytochrome-c peroxidase activity is a
diarylpropane peroxidase activity is a
fatty acid peroxidase activity is a
glutathione peroxidase activity is a
iodide peroxidase activity is a
L-ascorbate peroxidase activity is a
manganese peroxidase activity is a
NADH peroxidase activity is a
NADPH peroxidase activity is a
reactive-black-5:hydrogen-peroxide oxidoreductase activity is a
thiocyanate peroxidase activity is a
thioredoxin peroxidase activity is a
tryparedoxin peroxidase activity is a
peroxiredoxin activity is a
sulfiredoxin activity is a
superoxide dismutase activity is a
superoxide reductase activity is a
thioredoxin-disulfide reductase activity is a
cellular detoxification of hydrogen peroxide is a
removal of superoxide radicals is a
toxic metabolite repair is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a