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Gene ontology
Version 2014-12-22
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Details for dopamine beta-monooxygenase activity
1.14.17.1
Gene ontology ID
GO:0004500
Definition
Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O
Synonyms
1. (3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity
2. 3,4-dihydroxyphenethylamine beta-oxidase activity
3. 3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)
4. 4-(2-aminoethyl)pyrocatechol beta-oxidase activity
5. dopa beta-hydroxylase activity
6. dopamine b-hydroxylase activity
7. dopamine beta-hydroxylase activity
8. dopamine beta-oxidase activity
9. dopamine hydroxylase activity
10. dopamine-B-hydroxylase activity
11. MDBH (membrane-associated dopamine beta-monooxygenase)
12. oxygenase, dopamine beta-mono-
13. phenylamine beta-hydroxylase activity
14. SDBH (soluble dopamine beta-monooxygenase)
References
1. EC 1.14.17.1
2. RHEA: 19117
3. KEGG REACTION: R02535
4. MetaCyc DOPAMINE-BETA-MONOOXYGENASE-RXN
5. Reactome: R-HSA-209891 "Dopamine is oxidised to noradrenaline"
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