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Gene ontology
Version 2014-12-22
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Details for N,N-dimethylaniline monooxygenase activity
1.14.13.8
Gene ontology ID
GO:0004499
Definition
Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O
Synonyms
1. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity
2. dimethylaniline monooxygenase (N-oxide-forming) activity
3. dimethylaniline N-oxidase activity
4. dimethylaniline oxidase activity
5. DMA oxidase activity
6. FAD-containing monooxygenase activity
7. flavin mixed function oxidase activity
8. flavin monooxygenase activity
9. flavin-containing monooxygenase activity
10. FMO activity
11. FMO-I
12. FMO-II
13. FMO1
14. FMO2
15. FMO3
16. FMO4
17. FMO5
18. methylphenyltetrahydropyridine N-monooxygenase activity
19. mixed-function amine oxidase activity
20. N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming)
21. Ziegler's enzyme
References
1. EC 1.14.13.8
2. MetaCyc 1.14.13.8-RXN
3. Reactome: R-HSA-139970 "FMO3:FAD N-oxidises TMA to TMAO"
4. Reactome: R-HSA-217255 "FMO1:FAD N-oxidises TAM"
5. Reactome: R-HSA-5602966 "Defective FMO3 does not N-oxidise TMA"
6. RHEA: 24468
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