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Gene ontology
Version 2014-12-22
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Details for leukotriene-A4 hydrolase activity
3.3.2.6
Gene ontology ID
GO:0004463
Definition
Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4)
Synonyms
1. (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity
2. leukotriene A(4) hydrolase activity
3. leukotriene A4 hydrolase activity
4. LTA-4 hydrolase activity
5. LTA4 hydrolase activity
6. LTA4H
References
1. EC 3.3.2.6
2. RHEA: 22324
3. KEGG REACTION: R03057
4. MetaCyc LEUKOTRIENE-A4-HYDROLASE-RXN
5. Reactome: R-HSA-266072 "LTA4 is hydolysed to LTB4 by LTA4H"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
hydrolase activity is a
hydrolase activity, acting on ether bonds is a
ether hydrolase activity is a
leukotriene-A4 hydrolase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
beta-alanyl-dopamine hydrolase activity is a
beta-alanyl-histamine hydrolase activity is a
coenzyme F390-A hydrolase activity is a
coenzyme F390-G hydrolase activity is a
deacetylase activity is a
deaminase activity is a
hydrolase activity, acting on acid anhydrides is a
hydrolase activity, acting on acid carbon-carbon bonds is a
hydrolase activity, acting on acid carbon-phosphorus bonds is a
hydrolase activity, acting on acid halide bonds is a
hydrolase activity, acting on acid phosphorus-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-sulfur bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
hydrolase activity, acting on carbon-sulfur bonds is a
hydrolase activity, acting on ester bonds is a
hydrolase activity, acting on ether bonds is a
ether hydrolase activity is a
9,10-epoxy-18-hydroxystearate hydrolase activity is a
9,10-epoxystearate hydrolase activity is a
alkenylglycerophosphocholine hydrolase activity is a
alkenylglycerophosphoethanolamine hydrolase activity is a
aurachin C epoxide hydrolase/isomerase activity is a
cholesterol-5,6-oxide hydrolase activity is a
cis-stilbene-oxide hydrolase activity is a
epoxide hydrolase activity is a
glucosylglycerate hydrolase activity is a
hepoxilin-epoxide hydrolase activity is a
leukotriene-A4 hydrolase activity is a
mannosylglycerate hydrolase activity is a
pyrene-4,5-epoxide hydrolase activity is a
trans-epoxysuccinate hydrolase activity is a
trialkylsulfonium hydrolase activity is a
hydrolase activity, acting on glycosyl bonds is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a