2.5.1.10Gene ontology ID
GO:0004337
Definition
Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate
Comment
Note that this is the second step in the formation of farnesyl diphosphate. The first step is 'dimethylallyltransferase activity ; GO:0004161'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'.
Synonyms
1. farnesyl diphosphate synthetase activity
2. farnesyl pyrophosphate synthetase activity
3. farnesyl-diphosphate synthase activity
4. farnesylpyrophosphate synthetase activity
5. FPP synthetase activity
6. geranyl transferase I
7. geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity
8. geranyltransferase activity
References
1. EC 2.5.1.102. RHEA: 19361
3. KEGG REACTION: R02003
4. MetaCyc FPPSYN-RXN5. Reactome: R-HSA-191303 "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate"
6. Reactome: R-HSA-8870469 "RGGT geranylgeranylates RAB proteins"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA