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Gene ontology
Version 2014-12-22
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Details for amidophosphoribosyltransferase activity
2.4.2.14
Gene ontology ID
GO:0004044
Definition
Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O
Synonyms
1. 5'-phosphoribosylpyrophosphate amidotransferase activity
2. 5-phosphoribosyl-1-pyrophosphate amidotransferase activity
3. 5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)
4. 5-phosphororibosyl-1-pyrophosphate amidotransferase activity
5. alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity
6. glutamine 5-phosphoribosylpyrophosphate amidotransferase activity
7. glutamine phosphoribosyldiphosphate amidotransferase activity
8. glutamine phosphoribosylpyrophosphate amidotransferase activity
9. glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity
10. phosphoribose pyrophosphate amidotransferase activity
11. phosphoribosyl pyrophosphate amidotransferase activity
12. phosphoribosyldiphosphate 5-amidotransferase activity
13. phosphoribosylpyrophosphate glutamyl amidotransferase activity
References
1. EC 2.4.2.14
2. RHEA: 14905
3. KEGG REACTION: R01072
4. MetaCyc PRPPAMIDOTRANS-RXN
5. Reactome: R-HSA-73815 "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate"
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