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Gene ontology
Version 2014-12-22
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Details for GTP cyclohydrolase I activity
3.5.4.16
Gene ontology ID
GO:0003934
Definition
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate
Synonyms
1. dihydroneopterin triphosphate synthase activity
2. GTP 7,8-8,9-dihydrolase activity
3. GTP 8-formylhydrolase activity
4. guanosine triphosphate 8-deformylase activity
5. guanosine triphosphate cyclohydrolase activity
References
1. EC 3.5.4.16
2. KEGG REACTION: R00424
3. MetaCyc GTP-CYCLOHYDRO-I-RXN
4. Reactome: R-HSA-1474146 "GCH1 reduces GTP to dihydroneopterin triphosphate"
5. RHEA: 17473
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
hydrolase activity is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is a
cyclohydrolase activity is a
GTP cyclohydrolase activity is a
GTP cyclohydrolase I activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
beta-alanyl-dopamine hydrolase activity is a
beta-alanyl-histamine hydrolase activity is a
coenzyme F390-A hydrolase activity is a
coenzyme F390-G hydrolase activity is a
deacetylase activity is a
deaminase activity is a
hydrolase activity, acting on acid anhydrides is a
hydrolase activity, acting on acid carbon-carbon bonds is a
hydrolase activity, acting on acid carbon-phosphorus bonds is a
hydrolase activity, acting on acid halide bonds is a
hydrolase activity, acting on acid phosphorus-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-sulfur bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity is a
3-(N-formyl)-formiminopyruvate hydrolase activity is a
3-formiminopyruvate hydrolase activity is a
aminohydroquinone monooxygenase activity is a
gamma-aminovinylacetate deaminase activity is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is a
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity is a
5-fluorocytosine deaminase activity is a
8-oxoguanine deaminase activity is a
aminoimidazolase activity is a
cyclohydrolase activity is a
GTP cyclohydrolase activity is a
archaeal-specific GTP cyclohydrolase activity is a
GTP cyclohydrolase I activity is a
GTP cyclohydrolase II activity is a
GTP cyclohydrolase IIa activity is a
IMP cyclohydrolase activity is a
methenyltetrahydrofolate cyclohydrolase activity is a
methenyltetrahydromethanopterin cyclohydrolase activity is a
phosphoribosyl-AMP cyclohydrolase activity is a
N-cyclopropylammelide alkylamino hydrolase activity is a
N-cyclopropylammeline deaminase activity is a
N-cyclopropylmelamine deaminase activity is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles is a
hydroxydechloroatrazine ethylaminohydrolase activity is a
IAA-amino acid conjugate hydrolase activity is a
jasmonic acid hydrolase is a
jasmonyl-Ile conjugate hydrolase activity is a
N-acetyl-anhydromuramoyl-L-alanine amidase activity is a
N-isopropylammelide isopropylaminohydrolase activity is a
riboflavinase activity is a
thiaminase activity is a
trans-ACOHDA hydrolase activity is a
hydrolase activity, acting on carbon-sulfur bonds is a
hydrolase activity, acting on ester bonds is a
hydrolase activity, acting on ether bonds is a
hydrolase activity, acting on glycosyl bonds is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a