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Gene ontology
Version 2014-12-22
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Details for lanosterol synthase activity
5.4.99.7
Gene ontology ID
GO:0000250
Definition
Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus
Synonyms
1. (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)
2. 2,3-epoxysqualene lanosterol cyclase activity
3. 2,3-epoxysqualene--lanosterol cyclase activity
4. 2,3-epoxysqualene-lanosterol cyclase activity
5. 2,3-oxidosqualene sterol cyclase activity
6. 2,3-oxidosqualene-lanosterol cyclase activity
7. lanosterol 2,3-oxidosqualene cyclase activity
8. OSC
9. oxidosqualene--lanosterol cyclase activity
10. oxidosqualene-lanosterol cyclase activity
11. oxidosqualene:lanosterol cyclase activity
12. squalene 2,3-epoxide:lanosterol cyclase activity
13. squalene epoxidase-cyclase activity
14. squalene-2,3-oxide-lanosterol cyclase activity
References
1. EC 5.4.99.7
2. RHEA: 14621
3. KEGG REACTION: R03199
4. MetaCyc LANOSTEROL-SYNTHASE-RXN
5. Reactome: R-HSA-191366 "Squalene 2,3-epoxide cyclizes, forming lanosterol"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
isomerase activity is a
intramolecular transferase activity is a
oxidosqualene cyclase activity is a
lanosterol synthase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity is a
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity is a
cis-trans isomerase activity is a
dihydroneopterin triphosphate 2'-epimerase activity is a
eoxin A4 synthase activity is a
hepoxilin A3 synthase activity is a
hexulose-6-phosphate isomerase activity is a
intramolecular lyase activity is a
intramolecular oxidoreductase activity is a
intramolecular transferase activity is a
(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity is a
2-acetolactate mutase activity is a
2-methyleneglutarate mutase activity is a
4-carboxymethyl-4-methylbutenolide mutase activity is a
5-(carboxyamino)imidazole ribonucleotide mutase activity is a
camelliol C synthase activity is a
chorismate mutase activity is a
D-ribose pyranase activity is a
intramolecular transferase activity, phosphotransferases is a
intramolecular transferase activity, transferring acyl groups is a
intramolecular transferase activity, transferring amino groups is a
intramolecular transferase activity, transferring hydroxy groups is a
isobutyryl-CoA mutase activity is a
isomaltulose synthase activity is a
maltose alpha-D-glucosyltransferase activity is a
methylaspartate mutase activity is a
methylmalonyl-CoA mutase activity is a
o-hydroxylaminobenzoate mutase activity is a
oxidosqualene cyclase activity is a
alpha-amyrin synthase activity is a
arabidiol synthase activity is a
baruol synthase activity is a
beta-amyrin synthase activity is a
cucurbitadienol synthase activity is a
cycloartenol synthase activity is a
lanosterol synthase activity is a
lupeol synthase activity is a
marneral synthase activity is a
thalianol synthase activity is a
pivalyl-CoA mutase activity is a
pseudouridine synthase activity is a
UDP-arabinopyranose mutase activity is a
UDP-galactopyranose mutase activity is a
N-acylmannosamine-6-phosphate 2-epimerase activity is a
peroxynitrite isomerase activity is a
racemase and epimerase activity is a
sulfoquinovose isomerase activity is a
thiocyanate isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a