For more than a decade now we are developing the enzyme and metabolic
information system BRENDA. Since 1998 it is available as an INTERNET
resource to the scientific community and it is heavily used with several
thousand queries per day. We will continue the scientific development of
the database and are always grateful about comments to improve its
quality and usefulness.
Most of the money for the development of the database has come from
public sources so far. Unfortunately these sources are no longer
available for the further BASIC funding, i.e. the daily business of
extracting information from the primary literature. This reflects the
general policy of the European and German government not to fund
scientific infrastructure longer than a certain period of time. As we
are dedicated to continue this service we decided to keep the service
free for academic community whereas use by commercial users (presently
ca. 30% of the web queries) now requires a license.
Initially we had planned to keep the webpage open relying on the
fairness of our commercial users. Unfortunately the experiences of the
distributor of BRENDA has shown so far that many companies are unwilling
to buy the (legally required) license as long as their scientists can
access our service on the internet. Therefore we stopped the commercial
use of the BRENDA webpage without a license.
We have tried to find a solution that hampers the normal academic use of
BRENDA as little as possible. If you find that our present solution
creates any problems please send an e-mail to