Nitro analogs of substrates for argininosuccinate synthetase and argininosuccinate lyase

Raushel, F.M.; Arch. Biochem. Biophys. 232, 520-525 (1984)

 show all sequences of 6.3.4.5

Data extracted from this reference:

Organism
Organism Primary Accession No. (UniProt) Commentary Textmining
Bos taurus
-
-
-
Substrates and Products (Substrate)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
ATP + L-citrulline + L-Asp
-
 1588 Bos taurus AMP + diphosphate + L-argininosuccinate
-
 1588 Bos taurus
-
Substrates and Products (Substrate) (protein specific)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
ATP + L-citrulline + L-Asp
-
 1588 Bos taurus AMP + diphosphate + L-argininosuccinate
-
 1588 Bos taurus
-

See also following references to EC number 6.3.4.5 (sorted by year of publication):
No.1st authorPub
Med		titleorganimsjournalvolumepagesyearActivating CompoundApplicationCloned(Commentary)Crystallization (Commentary)EngineeringGeneral StabilityInhibitorsKM Value [mM]LocalizationMetals/IonsMolecular Weight [Da]Natural Substrates/ Products (Substrates)Organic Solvent StabilityOrganismOxidation StabilityPosttranslational ModificationPurification (Commentary)ReactionRenatured (Commentary)Source TissueSpecific Activity [micromol/min/mg]Storage StabilitySubstrates and Products (Substrate)SubunitsTemperature Optimum [°C]Temperature Range [°C]Temperature Stability [°C]Turnover Number [1/s]pH OptimumpH RangepH StabilityCofactorKi Value [mM]pI ValueIC50 ValueActivating Compound (protein specific)Application (protein specific)Cloned(Commentary) (protein specific)Cofactor (protein specific)Crystallization (Commentary) (protein specific)Engineering (protein specific)General Stability (protein specific)IC50 Value (protein specific)Inhibitors (protein specific)Ki Value [mM] (protein specific)KM Value [mM] (protein specific)Localization (protein specific)Metals/Ions (protein specific)Molecular Weight [Da] (protein specific)Natural Substrates/ Products (Substrates) (protein specific)Organic Solvent Stability (protein specific)Oxidation Stability (protein specific)Posttranslational Modification (protein specific)Purification (Commentary) (protein specific)Renatured (Commentary) (protein specific)Source Tissue (protein specific)Specific Activity [micromol/min/mg] (protein specific)Storage Stability (protein specific)Substrates and Products (Substrate) (protein specific)Subunits (protein specific)Temperature Optimum [°C] (protein specific)Temperature Range [°C] (protein specific)Temperature Stability [°C] (protein specific)Turnover Number [1/s] (protein specific)pH Optimum (protein specific)pH Range (protein specific)pH Stability (protein specific)pI Value (protein specific)ExpressionGeneral InformationGeneral Information (protein specific)Expression (protein specific)KCat/KM [mM/s]KCat/KM [mM/s] (protein specific)
715188PrimaInhibition of LPS toxicity by ...Homo sapiens, Mus musculusInt. Immunopharmacol.111180-118820112-2----------6-----4---2-----------2-2-----------------4---2---------11---
715624MunEndothelial argininosuccinate ...Homo sapiensJ. Biol. Chem.2862536-25422011-------------3-----1-----------------------------------1-------------11---
703251Ibarra-GonzalezClinical and biochemical chara ...Homo sapiensClin. Biochem.43461-4662010-------------3-----2-----------------------------------2-------------11---
704078DelageArginine deprivation and argin ...Homo sapiensInt. J. Cancer1262762-27722010-1------2----3-----5----------------1---------2--------5------------3223--
703248LarovereCitrullinemia type I, classica ...Homo sapiensClin. Biochem.421166-11682009----1--------5-----1--------------------1--------------1-------------22---
703594El FadiliDown regulation of KMP-11 in L ...Leishmania infantumExp. Parasitol.12351-572009-------------4------------------------------------------------------1--1--
703969EngelMutations and polymorphisms in ...Homo sapiensHum. Mutat.30300-3072009----21--------3--------------------------21----------------------------22---
704070NicholsonEpigenetic silencing of argini ...Homo sapiensInt. J. Cancer1251454-14632009-1-----------2-----3----------------1------------------3------------1111--
704509GuerreiroArgininosuccinate synthetase i ...Homo sapiens, Mus musculusJ. Biol. Chem.28420022-20033200922-----91-1--7--2--4--1-1---1------22--------91-1----2-4--1-1---1----22---
705506NagasakaEvaluation of endogenous nitri ...Homo sapiensMetab. Clin. Exp.58278-2822009-------------4-----1-----------------------------------1-------------22---
690234KarlbergStructure of human argininosuc ...Homo sapiensActa Crystallogr. Sect. D64279-2862008--111----1-2-3--1-----31-------1-----1111------1-2---1----31--------------
690727GoodwinTroglitazone up-regulates vasc ...Bos taurusBiochem. Biophys. Res. Commun.370254-25820081-1---1--1-1-1-----2--2--------1---1-11----1---1-1-----2--2---------------
690765CorbinPhosphorylation of argininosuc ...Bos taurusBiochem. Biophys. Res. Commun.3771042-10462008--1------1-1-2-11--3--2--------1-----11--------1-1--11-3--2---------------
690768GueiIdentification of a liver-spec ...Homo sapiensBiochem. Biophys. Res. Commun.377257-26120081-----1--1-2-4-----3--3--------1---1--1----1---1-2-----3--3---------------
692607SatohClearance of bacterial lipopol ...Mus musculusInnate Immun.1451-602008--------11-2-3-----2--3--------1------1-------11-2-----2--3---------------
692659BowlesPancreatic cancer cell lines d ...Homo sapiensInt. J. Cancer1231950-19552008------1--1-2-5-----8--2--------1------1----1---1-2-----8--2---------------
693030ZhaoAn NADPH sensor protein (HSCAR ...Homo sapiensJ. Biol. Chem.28311004-110132008--1-1----1-2-2-----2--3-1---1--1-----11-1------1-2-----2--3-1---1---------
671250GoodwinTumor necrosis factor-alpha re ...Bos taurusAm. J. Physiol. Heart Circ. Physiol.293H1115-H11212007-1-----------2-----2----------------1------------------2------------------
673486BizzocoTransient ischemia increases n ...Rattus norvegicusExp. Neurol.204252-2592007-1-----------4-----3----------------1------------------3------------------
674048SzlosarekAberrant regulation of arginin ...Homo sapiensInt. J. Cancer1216-112007-1-----------3-----5----------------1------------------5------------------
676120WagemakerArgininosuccinate synthetase a ...Agaricus bisporusMycol. Res.111493-5022007--1-1-----1--4-----4-----------------1--1-------1------4------------------
676636CruzEnzymatic evidence for the key ...Daucus carota, Rhizophagus intraradicesPlant Physiol.144782-7922007------2------5-----310-1-3---2--------------2-----------310-1-3---2---------
672445Brasse-LagnelBiphasic effect of IL-1beta on ...Homo sapiensBiochimie88607-61220061-----1------3-2---13---1----------1-------1--------2--13---1-------------
674383KimCharacterization of late-onset ...Homo sapiensJ. Biochem. Mol. Biol.39400-4052006-1-----------4----------------------1-------------------------------------
675096SatohLiver argininosuccinate syntha ...Mus musculusJ. Endotoxin Res.1221-382006-1----5--11--4--11-15-1-1---1-----1-1-----15---11----1-15-1-1---1---------
675606Endo-Functional complementation of ...Pyropia yezoensisJ. Phycol.421066-10712006-11-------1--1----------------------11----------1-------------------------
661285Brasse-LagnelIL-1beta stimulates argininosu ...Homo sapiensBiochimie87403-4092005-----------1-4-----1--1--------------------------1-----1--1---------------
662377PendletonRegulation of endothelial argi ...Bos taurusJ. Biol. Chem.28024252-242602005-----------1-2-----3--1--------------------------1-----3--1---------------
662205GoodwinArgininosuccinate synthase exp ...Bos taurusJ. Biol. Chem.27918353-183602004-----------1-2-----3--1--------------------------1-----3--1---------------
662254HaoArgininosuccinate synthetase i ...Homo sapiensJ. Biol. Chem.27936192-362002004--1---1----1-4--1-----1--------------1-----1-----1---1----1---------------
650761ShenResistance to the anti-prolife ...Canis lupus familiaris, Homo sapiens, Mus musculusCancer Lett.191165-17020032-----3----3-4---6--9-6-6----------2-------3-----3------9-6-6-------------
652404GotoStructures of argininosuccinat ...Thermus thermophilusJ. Biol. Chem.27822964-229712003--11-----1-1-5--11--2-21----1--------1-1-------1-1---1--2-21----1---------
653046HukkanenInduction of inducible nitric ...Mus musculusJ. Rheumatol.30652-6592003111--------1-4---1----1------------111-----------1--------1---------------
651195Van GeldreL-citrulline recycling by argi ...Rattus norvegicusEur. J. Pharmacol.455149-1602002------1----1-3---1-1--2--------------------1-----1-----1--2---------------
652231LemkeSubstrate induced conformation ...Escherichia coliJ. Biol. Chem.27713074-130812002--11-------1-3--11----21-------------1-1---------1---1----21--------------
652242GotoCrystal structure of argininos ...Thermus thermophilusJ. Biol. Chem.27715890-158962002--11-----1-1-4--11----21-------------1-1-------1-1---1----21--------------
652976HenekaNeuronal and glial coexpressio ...Homo sapiensJ. Neuropathol. Exp. Neurol.60906-9162001-1---------1-4---1----2-------------1------------1--------2---------------
653186KawaharaCo-induction of argininosuccin ...Mus musculus, Rattus norvegicusMol. Brain Res.90165-173200121---------2-4---2-1--21-----------21------------2-----1--21--------------
649104Lemke-Expression, purification, crys ...Escherichia coliActa Crystallogr. Sect. D552028-20301999--11-------1-1--11----21-------------1-1---------1---1----21--------------
653344HammermannInability of rat alveolar macr ...Rattus norvegicusNaunyn-Schmiedebergs Arch. Pharmacol.358601-60719981----------1-2---1-1--21-----------1-------------1-----1--21--------------
1590IsayamaDistribution and co-localizati ...Felis catusArch. Histol. Cytol.60477-4921997-------------4-----2--1--------------------------------2--1---------------
1591DemarquoyRegulation of argininosuccinat ...Rattus norvegicusMol. Cell. Biochem.14347-511995--------4--1-3--------2-----------------------4--1--------2---------------
1597YuPreparation of recombinant arg ...Rattus norvegicusJ. Biochem.117952-9571995--1----------5--1--2--1--------------1---------------1-2--1---------------
1592DemarquoyDemonstration of argininosucci ...Rattus norvegicusMol. Cell. Biochem.136145-1551994--------2----3-----1--1-----------------------2--------1--1---------------
1593PatejunasGeneration of a mouse model fo ...Mus musculusSomatic Cell Mol. Genet.2055-601994-------------6--------1-----------------------------------1---------------
1598ShaheenCharacterization of human wild ...Homo sapiensEnzyme Protein95251-2641994----4--13--12-4--1-----41----------------4----13--12---1----41--------------
1594Arnt-RamosImmunohistochemical localizati ...Rattus norvegicusNeuroscience51773-7891992-----------1-2-----3--2--------------------------1-----3--2---------------
1596WakuiRenal argininosuccinate synthe ...Sus scrofaRenal Physiol. Biochem.151-91992--------1-1--3--1--1--11----------------------1-1----1-1--11--------------
1595IsahikiIdentification of essential ar ...Homo sapiensProtein Seq. Data Anal.2283-2871989------4------3--------1--------------------4--------------1---------------
1584Saheki-Role of argininosuccinate synt ...Homo sapiens, Rattus norvegicusAdv. Enzyme Regul.18221-2381986-----------1-2--------3--------------------------1--------3---------------
1589KumarArgininosuccinate synthetase: ...Bos taurusProc. Natl. Acad. Sci. USA826745-67491985------1------2---1-1--1--------------------1-----------1--1---------------
1588RaushelNitro analogs of substrates fo ...Bos taurusArch. Biochem. Biophys.232520-5251984-------------2--------1-----------------------------------1---------------
1586SahekiSome properties of argininosuc ...Homo sapiens, Rattus norvegicusJ. Biochem.931531-15371983-------5--1--4--1--21-32---------------------5--1----1-21-32--------------
1587RaushellKinetic mechanism of argininos ...Bos taurusArch. Biochem. Biophys.225979-9851983------4------3---1-2--2--------------------4-----------2--2---------------
1585RatnerArgininosuccinate synthetase o ...Bos taurusProc. Natl. Acad. Sci. USA795197-51991982---1-1--1-1--3-----21-11---------------1-1----1-1------21-11--------------
1583KimballPurification and properties of ...Homo sapiensBiochemistry19705-7091980-------4--1--2--1--21-21---------------------4--1----1-21-21--------------
1578MatsudaStudies on liver argininosucci ...Homo sapiensJ. Biochem.85191-1951979-----1-3--1--1-----1--1---2--------------1---3--1------1--1---2-----------
1579HilgerYeast argininosuccinate synthe ...Saccharomyces cerevisiae 1278b, Saccharomyces cerevisiaeEur. J. Biochem.94153-1631979------3---11-4--11--1221----22-------------3----11---1--1221----22--------
1580TakadaStudies on rat liver argininos ...Rattus norvegicusJ. Biochem.851309-13141979---1--7------2-----2--1----------------1---7-----------2--1---------------
1581O'BrienIsolation and characterization ...Homo sapiensBiochemistry185353-53561979-------3--1--6--1--21111---------------------3--1----1-21111--------------
1582TakadaStudies of rat liver argininos ...Rattus norvegicusJ. Biochem.861353-13591979-----116-----2--1--2--11--1-1------------1-1-6-------1-2--11--1-1---------
1576SahekiStudies of rat liver argininos ...Rattus norvegicusJ. Biochem.81687-6961977---1--66--2--1-----1-131----2----------1---6-6--2------1-131----2---------
1577RochovanskyBiosynthesis of urea. Molecula ...Bos taurusJ. Biol. Chem.2525287-52941977---1--21--1--1--1--11121---------------1---2-1--1----1-11121--------------
1575SahekiCrystallization and some prope ...Rattus norvegicusFEBS Lett.58314-3171975---1---3-----2--1--21-21----1----------1-----3-------1-21-21----1---------
1574RatnerEnzymes of arginine and urea s ...Bos taurusAdv. Enzymol. Relat. Areas Mol. Biol.391-901973---1--63--1--1---1-21-41----2----------1---6-3--1------21-41----2---------
1573Shargool-Purification of argininosuccin ...Pisum sativumPhytochemistry102029-20321971------1------1--1--11-1-----1--------------1---------1-11-1-----1---------