Anaerobic toluene-catabolic pathway in denitrifying Thauera aromatica: activation and beta-oxidation of the first intermediate, (R)-(+)-benzylsuccinate

Leutwein, C.; Heider, J.; Microbiology 145, 3265-3271 (1999)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Commentary (Nat. Sub.)	Natural Products	Commentary (Nat. Pro.)	Organism (Nat. Pro.)	Reversibility
toluene + fumarate	Thauera aromatica	highly stereospecific, enantiomer purity for (R-)-(+)-benzylsuccinate 99%	benzylsuccinate	-	Thauera aromatica	?

Organism

Organism	Primary Accession No. (UniProt)	Commentary	Textmining
Thauera aromatica	-	-	-

Substrates and Products (Substrate)

Substrates	Commentary Substrates	Literature (Substrates)	Organism	Products	Commentary (Products)	Literature (Products)	Organism (Products)	Reversibility
toluene + fumarate	highly stereospecific, enantiomer purity for (R-)-(+)-benzylsuccinate 99%	210661	Thauera aromatica	benzylsuccinate	-	210661	Thauera aromatica	?

Natural Substrates/ Products (Substrates) (protein specific)

Natural Substrates	Organism	Commentary (Nat. Sub.)	Natural Products	Commentary (Nat. Pro.)	Organism (Nat. Pro.)	Reversibility
toluene + fumarate	Thauera aromatica	highly stereospecific, enantiomer purity for (R-)-(+)-benzylsuccinate 99%	benzylsuccinate	-	Thauera aromatica	?

Substrates and Products (Substrate) (protein specific)

Substrates	Commentary Substrates	Literature (Substrates)	Organism	Products	Commentary (Products)	Literature (Products)	Organism (Products)	Reversibility
toluene + fumarate	highly stereospecific, enantiomer purity for (R-)-(+)-benzylsuccinate 99%	210661	Thauera aromatica	benzylsuccinate	-	210661	Thauera aromatica	?

See also following references to EC number 4.1.99.11 (sorted by year of publication):

No.	1st author	Pub Med	title	organims	journal	volume	pages	year	Activating Compound	Application	Cloned(Commentary)	Crystallization (Commentary)	Engineering	General Stability	Inhibitors	KM Value [mM]	Localization	Metals/Ions	Molecular Weight [Da]	Natural Substrates/ Products (Substrates)	Organic Solvent Stability	Organism	Oxidation Stability	Posttranslational Modification	Purification (Commentary)	Reaction	Renatured (Commentary)	Source Tissue	Specific Activity [micromol/min/mg]	Storage Stability	Substrates and Products (Substrate)	Subunits	Temperature Optimum [°C]	Temperature Range [°C]	Temperature Stability [°C]	Turnover Number [1/s]	pH Optimum	pH Range	pH Stability	Cofactor	Ki Value [mM]	pI Value	IC50 Value	Activating Compound (protein specific)	Application (protein specific)	Cloned(Commentary) (protein specific)	Cofactor (protein specific)	Crystallization (Commentary) (protein specific)	Engineering (protein specific)	General Stability (protein specific)	IC50 Value (protein specific)	Inhibitors (protein specific)	Ki Value [mM] (protein specific)	KM Value [mM] (protein specific)	Localization (protein specific)	Metals/Ions (protein specific)	Molecular Weight [Da] (protein specific)	Natural Substrates/ Products (Substrates) (protein specific)	Organic Solvent Stability (protein specific)	Oxidation Stability (protein specific)	Posttranslational Modification (protein specific)	Purification (Commentary) (protein specific)	Renatured (Commentary) (protein specific)	Source Tissue (protein specific)	Specific Activity [micromol/min/mg] (protein specific)	Storage Stability (protein specific)	Substrates and Products (Substrate) (protein specific)	Subunits (protein specific)	Temperature Optimum [°C] (protein specific)	Temperature Range [°C] (protein specific)	Temperature Stability [°C] (protein specific)	Turnover Number [1/s] (protein specific)	pH Optimum (protein specific)	pH Range (protein specific)	pH Stability (protein specific)	pI Value (protein specific)	Expression	General Information	General Information (protein specific)	Expression (protein specific)	KCat/KM [mM/s]	KCat/KM [mM/s] (protein specific)
715671	Hilberg		Identification of FeS clusters ...	Escherichia coli	J. Biol. Inorg. Chem.	17	49-56	2012	-	-	1	-	-	-	-	-	-	1	-	-	-	3	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	-	-	-	-	-	-	-	1	-	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
704111	Winderl		DNA-SIP identifies sulfate-red ...	Desulfosporosinus sp.	ISME J.	4	1314-1325	2010	-	-	-	-	-	-	-	-	-	-	-	-	-	4	-	-	-	-	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-	1	1	-	-	-
691008	Li		Subunit structure of benzylsuc ...	Thauera aromatica	Biochemistry	48	1284-1292	2009	-	-	1	-	-	-	-	-	-	-	4	1	-	4	-	-	1	-	1	-	-	-	1	2	-	-	-	-	-	-	-	1	-	-	-	-	-	1	1	-	-	-	-	-	-	-	-	-	4	1	-	-	-	1	1	-	-	-	1	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-
692107	Musat		Anaerobic degradation of napht ...	uncultured delta proteobacterium	Environ. Microbiol.	11	209-219	2009	-	-	-	-	-	-	-	-	-	-	-	-	-	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
702892	Salinero		Metabolic analysis of the soil ...	no activity in Dechloromonas aromatica RCB	BMC Genomics	10	351	2009	-	-	-	-	-	-	-	-	-	-	-	-	-	5	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
703741	Weelink		A strictly anaerobic betaprote ...	Georgfuchsia toluolica	FEMS Microbiol. Ecol.	70	575-585	2009	-	-	-	-	-	-	-	-	-	-	-	-	-	9	-	-	-	-	-	1	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	1	-	-	-	-	-	-	-	-	-	-	1	1	-	-	-
692113	Vogt		Evaluation of toluene degradat ...	Azoarcus sp., Blastochloris sulfoviridis, Desulfosarcina cetonica, Thauera aromatica	Environ. Sci. Technol.	42	7793-7800	2008	-	4	-	-	-	-	-	-	-	-	-	4	-	8	-	-	-	-	-	-	-	-	4	-	-	-	-	-	-	-	-	-	-	-	-	-	4	-	-	-	-	-	-	-	-	-	-	-	-	4	-	-	-	-	-	-	-	-	4	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
679528	Winderl		Detection of anaerobic toluene ...	Azoarcus sp., Desulfobacula toluolica, Desulfosarcina cetonica, Desulfotomaculum sp., Geobacter grbiciae, Geobacter sp., Thauera aromatica	Environ. Microbiol.	9	1035-1046	2007	-	7	-	-	-	-	-	-	-	-	-	7	-	11	7	-	-	-	-	-	-	-	7	-	-	-	-	-	-	-	-	-	-	-	-	-	7	-	-	-	-	-	-	-	-	-	-	-	-	7	-	7	-	-	-	-	-	-	7	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
677932	Bhandare		Site-directed mutagenesis of t ...	Thauera aromatica	Biochem. Biophys. Res. Commun.	346	992-998	2006	1	-	-	-	2	-	-	-	-	-	-	1	-	4	1	-	-	-	-	-	-	-	1	1	-	-	-	-	-	-	-	-	-	-	-	1	-	-	-	-	2	-	-	-	-	-	-	-	-	1	-	1	-	-	-	-	-	-	1	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-
678164	Li		Deuterium isotope effects in t ...	Thauera aromatica	Biochemistry	45	13932-13938	2006	-	-	-	-	-	-	-	-	-	-	-	1	-	2	1	-	1	1	-	-	2	-	1	1	-	-	-	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	1	-	1	-	-	2	-	1	1	-	-	-	2	-	-	-	-	-	-	-	-	-	-
665307	Qiao		Mechanism of benzylsuccinate s ...	Thauera aromatica	J. Am. Chem. Soc.	127	8608-8609	2005	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	-	-	-	1	-	-	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
663790	Verfürth		Substrate specificities and el ...	Azoarcus sp., Thauera aromatica	Arch. Microbiol.	181	155-162	2004	-	-	-	-	-	-	-	-	-	-	-	-	-	6	-	-	-	-	-	-	-	-	14	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	14	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
210658	Krieger		A stable organic free radical ...	Azoarcus sp.	J. Biol. Chem.	276	12924-12927	2001	-	-	-	-	-	-	-	-	-	-	-	1	-	4	-	-	-	1	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	-	-	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
210659	Beller		Anaerobic toluene activation b ...	Desulfotomaculum, Methanosaeta sp., Methanospirillum sp.	Appl. Environ. Microbiol.	66	5503-5505	2000	-	-	-	-	-	-	-	-	-	-	-	3	-	5	-	-	-	-	-	-	3	-	3	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	3	-	-	-	-	-	-	3	-	3	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
210660	Beller		Substrate range of benzylsucci ...	Azoarcus sp.	FEMS Microbiol. Lett.	178	147-153	1999	-	-	-	-	-	-	-	-	-	-	1	1	-	3	-	-	1	-	-	-	1	-	9	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	1	-	-	-	1	-	-	1	-	9	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-
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