Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate

Barends, T.R.; Domratcheva, T.; Kulik, V.; Blumenstein, L.; Niks, D.; Dunn, M.F.; Schlichting, I.; ChemBioChem 9, 1024-1028 (2008)

Data extracted from this reference:

Cloned(Commentary)

Commentary	Organism
-	Salmonella enterica subsp. enterica serovar Typhimurium

Crystallization (Commentary)

Crystallization	Organism
the crystal structure of tryptophan synthase is determined at 2.1 A resolution	Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Commentary (Nat. Sub.)	Natural Products	Commentary (Nat. Pro.)	Organism (Nat. Pro.)	Reversibility
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	Salmonella enterica subsp. enterica serovar Typhimurium	-	indole + D-glyceraldehyde 3-phosphate	-	-	?

Organism

Organism	Primary Accession No. (UniProt)	Commentary	Textmining
Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Purification (Commentary)

Commentary	Organism
-	Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates	Commentary Substrates	Literature (Substrates)	Organism	Products	Commentary (Products)	Literature (Products)	Organism (Products)	Reversibility
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	-	691784	Salmonella enterica subsp. enterica serovar Typhimurium	indole + D-glyceraldehyde 3-phosphate	-	-	-	?

Cloned(Commentary) (protein specific)

Commentary	Organism
-	Salmonella enterica subsp. enterica serovar Typhimurium

Crystallization (Commentary) (protein specific)

Crystallization	Organism
the crystal structure of tryptophan synthase is determined at 2.1 A resolution	Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates) (protein specific)

Natural Substrates	Organism	Commentary (Nat. Sub.)	Natural Products	Commentary (Nat. Pro.)	Organism (Nat. Pro.)	Reversibility
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	Salmonella enterica subsp. enterica serovar Typhimurium	-	indole + D-glyceraldehyde 3-phosphate	-	-	?

Purification (Commentary) (protein specific)

Commentary	Organism
-	Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate) (protein specific)

Substrates	Commentary Substrates	Literature (Substrates)	Organism	Products	Commentary (Products)	Literature (Products)	Organism (Products)	Reversibility
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	-	691784	Salmonella enterica subsp. enterica serovar Typhimurium	indole + D-glyceraldehyde 3-phosphate	-	-	-	?

See also following references to EC number 4.1.2.8 (sorted by year of publication):

No.	1st author	Pub Med	title	organims	journal	volume	pages	year	Activating Compound	Application	Cloned(Commentary)	Crystallization (Commentary)	Engineering	General Stability	Inhibitors	KM Value [mM]	Localization	Metals/Ions	Molecular Weight [Da]	Natural Substrates/ Products (Substrates)	Organic Solvent Stability	Organism	Oxidation Stability	Posttranslational Modification	Purification (Commentary)	Reaction	Renatured (Commentary)	Source Tissue	Specific Activity [micromol/min/mg]	Storage Stability	Substrates and Products (Substrate)	Subunits	Temperature Optimum [°C]	Temperature Range [°C]	Temperature Stability [°C]	Turnover Number [1/s]	pH Optimum	pH Range	pH Stability	Cofactor	Ki Value [mM]	pI Value	IC50 Value	Activating Compound (protein specific)	Application (protein specific)	Cloned(Commentary) (protein specific)	Cofactor (protein specific)	Crystallization (Commentary) (protein specific)	Engineering (protein specific)	General Stability (protein specific)	IC50 Value (protein specific)	Inhibitors (protein specific)	Ki Value [mM] (protein specific)	KM Value [mM] (protein specific)	Localization (protein specific)	Metals/Ions (protein specific)	Molecular Weight [Da] (protein specific)	Natural Substrates/ Products (Substrates) (protein specific)	Organic Solvent Stability (protein specific)	Oxidation Stability (protein specific)	Posttranslational Modification (protein specific)	Purification (Commentary) (protein specific)	Renatured (Commentary) (protein specific)	Source Tissue (protein specific)	Specific Activity [micromol/min/mg] (protein specific)	Storage Stability (protein specific)	Substrates and Products (Substrate) (protein specific)	Subunits (protein specific)	Temperature Optimum [°C] (protein specific)	Temperature Range [°C] (protein specific)	Temperature Stability [°C] (protein specific)	Turnover Number [1/s] (protein specific)	pH Optimum (protein specific)	pH Range (protein specific)	pH Stability (protein specific)	pI Value (protein specific)	Expression	General Information	General Information (protein specific)	Expression (protein specific)	KCat/KM [mM/s]	KCat/KM [mM/s] (protein specific)
691511	Kriechbaumer		Characterisation of the trypto ...	Zea mays	BMC Plant Biol.	8	1-11	2008	-	-	1	-	-	-	-	1	1	-	-	1	-	4	-	-	1	-	-	1	-	-	1	-	1	-	-	1	1	-	-	-	-	-	-	-	-	1	-	-	-	-	-	-	-	1	1	-	-	1	-	-	-	1	-	1	-	-	1	-	1	-	-	1	1	-	-	-	-	-	-	-	-	-
691784	Barends		Structure and mechanistic impl ...	Salmonella enterica subsp. enterica serovar Typhimurium	ChemBioChem	9	1024-1028	2008	-	-	1	1	-	-	-	-	-	-	-	1	-	1	-	-	1	-	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	1	-	-	-	-	-	-	-	-	-	1	-	-	-	1	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
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670511	Frey		Transcriptional activation of ...	Zea mays	Phytochemistry	65	1047-1055	2004	-	-	-	-	-	-	-	-	-	-	-	1	-	3	-	-	-	-	-	-	-	-	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	-	-	-	-	-	-	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
670717	Frey		An herbivore elicitor activate ...	Zea mays	Proc. Natl. Acad. Sci. USA	97	14801-14806	2000	1	-	1	-	-	-	-	1	-	-	-	1	-	4	-	-	-	-	-	1	-	-	2	-	-	-	-	1	-	-	-	-	-	-	-	1	-	1	-	-	-	-	-	-	-	1	-	-	-	1	-	-	-	-	-	1	-	-	2	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-
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670884	Frey		Analysis of a chemical plant d ...	Zea mays	Science	277	696-699	1997	-	-	-	-	-	-	-	-	-	-	-	1	-	2	-	-	-	-	-	1	-	-	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	-	-	-	1	-	-	2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
669170	Yanofsky		The enzymatic conversion of an ...	Escherichia coli	J. Biol. Chem.	223	171-184	1956	-	-	-	-	-	-	-	-	-	-	-	-	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-